UNITED STATES

                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549

                                    FORM 10-K

(Mark One)
(X)      Annual  Report  Pursuant  to  Section  13 or 15(d) of the  Securities
         Exchange Act of 1934. For the fiscal year ended December 31, 1995 or

( )      Transition  Report  Pursuant to Section 13 or 15(d) of the Securities
         Exchange Act of 1934. For the transition period from__________ to
         __________.

                         Commission file number 2-89283

                           IOWA FIRST BANCSHARES CORP.
             (Exact name of registrant as specified in its charter)

An Iowa Corporation  
42-1211285
(State or other jurisdiction of 
(I.R.S Employer incorporation or organization)
Identification No.)

300 East Second Street, Muscatine, Iowa 
52761
(Address of principal executive offices)
(Zip Code)

Registrant's telephone number, including area code   (319) 263-4221
Securities registered pursuant to Section 12(b) of the Act:  None
Securities registered pursuant to Section 12(g) of the Act:  None

Indicate by check mark whether the registrant (1) has filed all reports required
to be filed by Section 13 or 15(d) of the Securities Exchange Act of 1934 during
the  preceding 12 months (or for such  shorter  period that the  registrant  was
required  to file  such  reports),  and  (2) has  been  subject  to such  filing
requirements for the past 90 days.

                    X    Yes                     No

Indicate by check mark if disclosure of delinquent  filers  pursuant to Item 405
of Regulation  S-K is not contained  herein,  and will not be contained,  to the
best of registrant's  knowledge,  in definitive proxy or information  statements
incorporated by reference in Part III of this Form 10-K or any amendment to this
Form 10-K. (X)

The  aggregate  market  value of the voting stock held by  nonaffiliates  of the
registrant as of February 29, 1996,  was  $21,602,547.  As of February 29, 1996,
570,463 shares of the Registrant's common stock were outstanding.

Documents incorporated by reference:

Portions of the registrant's  1995Annual  Report are incorporated in Parts I and
II of this Form 10-K.  Portions of the registrant's  Proxy Statement dated March
22, 1996 are incorporated in Part III of this Form 10-K.

The Exhibit Index is located on page  .








                           ANNUAL REPORT ON FORM 10-K


                                TABLE OF CONTENTS

                                     PART I
                                                                            Page
                                                                             No.

Item  1.  Business                                                           
Item  2.  Properties                                                         
Item  3.  Legal Proceedings                                                   
Item  4.  Submission of Matters to a Vote of Security Holders                 
Table I.  Executive Officers of the Registrant                                

                                     PART II

Item 5.   Market  for the  Registrant's  Common  Equity and  Related  
          Stockholder Matters                                                  
Item 6.   Selected Financial Data                                              
Item 7.   Management's  Discussion and Analysis of Financial  
          Condition and Results of  Operations                                
Item 8.   Financial Statements and Supplementary  Data                         
Item 9.   Changes in and  Disagreements  with Accountants on 
          Accounting and Financial Disclosure                                 


                                    PART III

Item 10.  Directors and Executive Officers of the Registrant                  
Item 11.  Executive Compensation                                              
Item 12.  Security Ownership of Certain Beneficial Owners and Management      
Item 13.  Certain Relationships and Related Transactions                      


                                     PART IV

Item 14.  Exhibits, Financial Statement Schedules, and Reports on 
          Form 8-K                                                           
          Signatures                                                         
          Index of Exhibits                                                  







                           ANNUAL REPORT ON FORM 10-K

                                     PART I


ITEM 1.   BUSINESS.

Iowa  First  Bancshares  Corp.  (the  "Company"),  is  a  bank  holding  company
headquartered in Muscatine,  Iowa. The Company owns all the outstanding stock of
two national banks in Iowa,  First National Bank of Muscatine and First National
Bank in Fairfield.

On a full-time  equivalent  basis,  year-end  employment for the Company and its
subsidiary banks totaled 113 employees.

First  National  Bank of Muscatine  has a total of four  locations in Muscatine,
Iowa. First National Bank in Fairfield has one location in Fairfield, Iowa. Each
bank is engaged in the general  commercial  banking  business and provides  full
service banking to individuals and  businesses,  including  checking and savings
accounts,  commercial  loans,  consumer loans,  real estate loans,  safe deposit
facilities,  transmitting  of funds,  trust  services,  and such  other  banking
services as are usual and customary for commercial banks.

The commercial banking business is highly competitive.  Subsidiary banks compete
with other  commercial  banks and with other financial  institutions,  including
savings and loan associations, savings banks, mortgage banking companies, credit
unions and mutual funds.  In recent years,  competition  also has increased from
institutions  not subject to the same regulatory  restrictions as banks and bank
holding companies.

The operations of the Company and its subsidiary banks are affected by state and
federal legislative  changes and by policies of various regulatory  authorities.
The Company is a registered  bank holding company under the Bank Holding Company
Act of 1956 (the "Act") and is subject to the supervision of, and regulation by,
the Board of Governors of the Federal  Reserve System (the  "Board").  Under the
Act, a bank  holding  company  may engage in banking,  managing  or  controlling
banks,  furnishing or performing services for banks it controls,  and conducting
activities that the Board has determined to be closely related to banking.

National  banks are  subject to the  supervision  of, and are  examined  by, the
Office of the Comptroller of the Currency.  Both subsidiary banks of the Company
are members of the  Federal  Deposit  Insurance  Corporation,  and as such,  are
subject to examination thereby. In practice, the primary federal regulator makes
regular examinations of each subsidiary bank subject to its regulatory review or
participates in joint examinations with other federal regulators.  Areas subject
to regulation by these  authorities  include capital  levels,  the allowance for
possible  loan losses,  investments,  loans,  mergers,  issuance of  securities,
payment of  dividends,  establishment  of  branches,  and many other  aspects of
operations.

Statistical  information  called for by this Item is contained in the  Company's
1995 Annual Report to Shareholders  which is incorporated by reference.




ITEM 2.   PROPERTIES.

Since the Company commenced  business,  its principal  executive office has been
located at 300 East  Second  Street,  Muscatine,  Iowa,  which is the  principal
office of First National Bank of Muscatine, a national banking association and a
wholly owned subsidiary of the Company.

First National Bank of Muscatine conducts its operations from four
facilities  located in  Muscatine.  The main bank is located at 300 East  Second
Street and is a modern brick and steel building completed in 1979 containing
36,000  square  feet of floor  space on three  floors.  The bank  owns  both the
building and the underlying  real estate.  All  administrative  functions of the
bank are conducted at its main  offices.  Portions of the building are leased to
commercial tenants. The three-lane drive-up facility of the main bank is located
approximately  one block north of the main bank at Third and Cedar Streets.  The
bank owns the drive-up facility and the underlying real estate.

Two locations provide banking services outside the Muscatine  downtown area. The
office at the Muscatine Mall is  approximately  two miles  northeast of the main
bank.  The  facility  contains  2,304  square feet of floor space in a one-story
concrete  and steel  building.  The  facility  offers a walk-in  lobby and night
depository.   The  three-lane  drive-up  facility  of  this  branch  is  located
approximately  500 feet west of the branch at the parking  lot of the mall.  The
building,  drive-up  facilities,  and real  estate  are  leased  from Aetna Life
Insurance Company. The terms of the lease provide for monthly payments of $2,304
during the current 5-year term of the lease. This lease expires on May 31, 1999.

The  bank's  southside  office  at 608  Grandview  Avenue is  located  two miles
southwest of the main bank. The office contains 3,600 square feet of floor space
and is located in a one-story steel frame concrete block building.  The facility
offers a walk-in lobby and three drive-up  lanes as well as a night  depository.
The building and underlying  real estate are owned by the bank.  Portions of the
building are leased to commercial tenants.

First National Bank in Fairfield conducts its operations from a modern brick and
steel building  completed in 1968 containing 8,200 square feet of floor space on
two floors.  The bank owns both the  building  and the  underlying  real estate.
Portions  of the  building  are leased to  commercial  tenants.  The  three-lane
drive-up facility of the bank is located at the main bank.


The Company's  facilities are well maintained and are suitable for the Company's
business operations.



ITEM 3.   LEGAL PROCEEDINGS.

          The Company has no pending legal proceedings which are material.


ITEM 4.   SUBMISSION OF MATTERS TO A VOTE OF SECURITY HOLDERS.

          None.




                                 PART I, TABLE I
                      EXECUTIVE OFFICERS OF THE REGISTRANT




                                Family                            Position       Business Experience
Name                   Age   Relationship      Position          Held Since     During Past Five Years
- ----                   ---   ------------      --------          ----------     ----------------------
                                                                   


George A. Shepley      73        None      Chairman of the Board    1983        President of the Company,
                                           President                1989          January 1989 to present;
                                           Chief Executive Officer  1983          Chairman of the Board,
                                           Director                 1983          Chief Executive Officer of the Company, 1983 to
                                                                                  present; Chairman of the Board, 1987 to present;
                                                                                  President, 1963 to January 1989, First
                                                                                  National Bank of Muscatine; Chairman of
                                                                                  the Board, 1986 to present, First National
                                                                                  Bank in Fairfield 

Kim K. Bartling        38        None      Senior Vice President    1988        Senior Vice President,
                                           Chief Financial Officer  1988          Chief Financial Officer
                                           Treasurer                1988          and Treasurer of the
                                           Director                 1994          Company, April 1988
                                                                                  to Present; Director
                                                                                  First National Bank of Muscatine, to present;
                                                                                  Senior Vice President/Chief Financial Officer,
                                                                                  First National Bank of Muscatine, to present;
                                                                                  Vice President/Chief Financial Officer of the
                                                                                  Company, May to April 1988 

Patricia R             48       None       secretary                1986        Corporate Secretary of
Thirtyacre                                                                        the Company, October 1986 to present .........







                                     PART II

ITEM 5.  MARKET  FOR THE  REGISTRANT'S  COMMON  EQUITY AND  RELATED  STOCKHOLDER
         MATTERS


          A market for the Company's common stock is made by the brokerage firms
of  Piper  Jaffray  Inc.,  Howe  Barnes   Investments,   Inc.  and  The  Chicago
Corporation.

          High and low common stock prices and  dividends for the last two years
were:



1995 by                                                                                                                     Dividend
Quarters                                                                      High                   Low                   Per Share
- --------                                                                   ---------              ---------                ---------
                                                                                                                  

First .................................................                    $   41.50              $   39.25                 $   0.70
Second ................................................                        43.00                  41.50                     0.37
Third .................................................                        46.50                  43.00                     0.39
Fourth ................................................                        50.00                  45.50                     0.41


Total Dividend
Paid ..................................................                    $    1.87



1994 by  
Quarters  
- --------   

First .................................................                    $   34.75              $   34.00                 $   0.60
Second ................................................                        35.50                  34.50                     0.00
Third .................................................                        37.00                  34.50                     0.65
Fourth ................................................                        38.00                  36.50                     0.00

Total Dividend
Paid ..................................................                    $    1.25



          The  above  quotations  were  furnished  by  Piper  Jaffray  Inc.  The
quotations  represent  prices between  dealers and do not include retail markup,
markdown, or
commissions.

          Dividends  were  declared  and  paid  semi-annually   until  quarterly
dividend  declarations  began  in the  first  quarter  of 1995  with  the  first
quarterly dividend payment in the second quarter of 1995.

    Future dividends are dependent on future earnings,  regulatory  restrictions
(see Management's  Discussion and Analysis of Financial Condition and Results of
Operations; and Note 7 to the Company's  Consolidated Financial Statements in
the  Company's  1995 Annual  Report to  Shareholders  which is  incorporated  by
reference), capital requirements, and the Company's financial condition.

     As of February 29, 1996, the Company had  approximately 375 shareholders of
its outstanding class of common stock. The Iowa First Bancshares Corp.  Employee
Stock Ownership Plan with 401(k) Provisions is considered one shareholder as all
shares owned by this plan are voted by the trustees of said plan unless the vote
in  question  encompasses  approval  or  disapproval  of any  corporate  merger,
consolidation, dissolution, or similar transaction.




ITEM 6.   SELECTED FINANCIAL DATA.

          The information  called for by this Item is contained in the Company's
1995 Annual Report to  Shareholders  which is incorporated by reference.



ITEM 7. MANAGEMENT'S  DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS
        OF OPERATIONS.

          The information  called for by this Item is contained in the Company's
1995 Annual Report to Shareholders  which is incorporated by reference.



ITEM 8.   FINANCIAL STATEMENTS AND SUPPLEMENTARY DATA.

          The information  called for by this Item is contained in the Company's
1995 Annual Report to Shareholders  which is incorporated by reference.



ITEM  9.  CHANGES  IN AND  DISAGREEMENTS  WITH  ACCOUNTANTS  ON  ACCOUNTING  AND
          FINANCIAL DISCLOSURE.

          None.



ITEM 10.  DIRECTORS AND EXECUTIVE OFFICERS OF THE REGISTRANT

                          IOWA FIRST BANCSHARES CORP.

                                   DIRECTORS


                                                                                                        As of February 28, 1996
                                                                                                              Common Stock
                                                                                                        -----------------------
                                                                                                         Amount and
                         Position(s)                                                        Nominated    Nature of     Percent
                         Held with                                                 Director For Term     Beneficial      of
Nominees                 the Company                                         Age     Since  Expiring     Ownership      Class
- --------                 -----------                                         ---   -------- ---------   ------------   -------
                                                                                                     

Craig R. Foss            Director                                             46     1994     1999          820          *

Donald R Heckman         Director                                             57     1984     1999        6,020         1.06%

D. Scott Ingstad         Director, President and CEO, First National
                         Bank of Muscatine                                    45     1990     1999        5,764         1.01%

Beverly J. White         Director                                             56     1988     1999        6,008         1.05%



Continuing                                                                      Term
Directors                                                                       Expires
- ----------                                                                      -------

Kim K. Bartling          Director.  Senior Vice President, Chief Financial
                         Officer, and Treasurer                               38    1994      1997        9,435         1.65%

Roy J. Carver, Jr.       Director                                             52    1989      1998        7,468         1.31%

Larry L. Emmert          Director                                             54    1993      1997        3,650          *

Dean H. Holst            Director. President and CEO, First National
                         Bank in Fairfield                                    56    1985      1998        5,929         1.04%

Dr. Victor G.            Director                                             52    1994      1998        1,050          *
McAvoy

George A. Shepley        Chairman of the Board, President and CEO             73    1983      1997       34,639         6.07%

Carl J. Spaeth           Director                                             78    1984      1997       57,630        10.10%



*   Less than 1 percent of the outstanding stock of the Company.

Shares listed as beneficially owned include vested, but unexercised,  options to
purchase  shares of the Company's stock and, for Directors who are also officers
of the Company,  shares held in the Company's retirement plan for the benefit of
such individuals.



          Director Compensation

          The annual retainer that each outside Director of the Company received
in 1995 was $4,800. During 1995, each Director of the Company served as Director
and  member  of  committees  for  subsidiary  boards  and  committees,  with the
exception of Mr. Carver who served only as a Director of the Company. The annual
retainer fee paid to each outside subsidiary  Director was $3,600. Fees paid for
attendance at committee  meetings and special Board of Directors  meetings range
from $50 to $100 per meeting.  Executive officers who also serve on the Board of
Directors do not receive such retainer or committee fees.


ITEM 11.  EXECUTIVE COMPENSATION

         The  information  called for by this Item is contained in the Company's
1995 Proxy Statement which is incorporated by reference.


ITEM 12.  SECURITY OWNERHSIP OF CERTAIN BENEFICIAL OWNERS AND MANAGEMENT.

         The  information  called for by this Item is contained in the Company's
1995 Proxy Statement which is incorporated by reference.


ITEM 13.  CERTAIN RELATIONSHIPS AND RELATED TRANSACTIONS.

         Officers and  Directors of the Company and its  subsidiaries  have had,
and may have in the  future,  banking  transactions  in the  ordinary  course of
business  of  the  Company's   subsidiaries.   All  such   transactions  are  on
substantially the same terms,  including interest rates on loans and collateral,
as those prevailing at the time for comparable transactions with others, involve
no more than the normal risk of collectibility, and present no other unfavorable
features.




                                     PART IV

ITEM 14. EXHIBITS, FINANCIAL STATEMENT SCHEDULES, AND REPORTS ON FORM 8-K.

          (a) Documents Filed with This Report:

               (1) Financial Statements.  The following  consolidated  financial
           statements of the Company and its  subsidiaries  are  incorporated by
           reference from the 1995 Annual Report to Shareholders of the Company:

                                                                           Page

           Consolidated balance sheets -- dated December 31, 1995 
             and 1994.                                                       

           Consolidated statements of income -- years ended 
             December 31, 1995, 1994, and 1993.                              

           Consolidated statements of stockholders' equity -- 
             years ended December 31, 1995, 1994, and 1993.                  

           Consolidated statements of cash flows - years ended
             December 31, 1995, 1994, and 1993.                              

           Notes to consolidated financial statements.                       

           Opinion of independent accountants.                               

               (2)  Financial  Statement  Schedules.  All  schedules are omitted
           because they are not  applicable,  are not  required,  or because the
           required  information is included in the financial  statements or the
           notes thereto.

          (b)   Reports on Form 8-K.

                No reports on Form 8-K have been filed  during the last  quarter
                of the period covered by this report.

           (c)  Exhibits.  

                The  following  exhibits  are  attached  pursuant to Item 601 of
                Regulation S-K:

                  (10a)  Employment Agreement                                
                  (10b)  Change in Control Employment Agreement              
                  (11)   Statement re Computation of Per Share Earnings      
                  (13)   Registrant's 1995 Annual Report to Shareholders     
                  (20)   Registrant's Proxy Statement dated March 22, 1996   
                  (21)   Subsidiaries of the Registrant                      
                  (27)   Financial Data Schedule                             


        See  Exhibit  Index for a  complete  list of  management  contracts  and
arrangements  required by this item and all other Exhibits filed or incorporated
by reference as a part of this report.





                                   SIGNATURES

         Pursuant to the  requirements  of Section 13 or 15(d) of the Securities
Exchange Act of 1934, the registrant has duly caused this report to be signed on
its behalf by the undersigned, thereunto duly authorized.

                           IOWA FIRST BANCSHARES CORP.

Date:  March 15, 1996                                     /S/ George A. Shepley
       --------------                                     ----------------------
                                                          George A. Shepley
                                                          Chairman of the  Board

         Pursuant to the  requirements  of the Securities  Exchange Act of 1934,
this  report has been  signed  below by the  following  persons on behalf of the
registrant and in the capacities and on the dates indicated.



         Signature                                Title                                       Date
         ---------                                -----                                       ----
                                                                                       

/s/ George A. Shepley              Chairman of the Board,                                   March 15,1996
- ---------------------              President, Chief Executive
George A. Shepley                  Officer, and Director            
                                   (Principal Executive Officer)


/s/ Kim K. Bartling                Senior Vice President, Chief Financial Officer           March 15, 1996
- ----------------------             and Treasurer                                          
Kim K. Bartling                    (Principal Financial and Accounting Officer)


/s/ Roy J. Carver, Jr.             Director                                                 March 15, 1996
- ----------------------                                                                 
Roy J. Carver, Jr.

/s/ Larry L. Emmert                Director                                                 March 15, 1996
- -------------------                                                                    
Larry L. Emmert

/s/ Craig R. Foss                  Director                                                 March 15, 1996
- -----------------                                                                         
Craig R. Foss

/s/ Donald R. Heckman              Director                                                 March 15, 1996
- ---------------------                                                                   
Donald R. Heckman

/s/ Dean H. Holst                  Director                                                 March 15, 1996
- -----------------                                                                       
Dean H. Holst

/s/ D. Scott Ingstad               Director                                                 March 15, 1996
- --------------------                                                                   
D. Scott Ingstad

/s/ Victor G. McAvoy               Director                                                 March 15, 1996
- --------------------                                                                   

/s/ Carl J. Spaeth                 Director                                                 March 15, 1996
- ------------------                                                                       
Carl J. Spaeth

/s/ Beverly J. White               Director                                                 March 15, 1996
- --------------------                                                                   
Beverly J. White







                       ITEM 14 (a) (3) - INDEX OF EXHIBITS




         Exhibit                                                           Page

(10a)    Employment Agreement                                                

(10b)    Change in Control Employment Agreement                              

(10c)    Incentive Stock Option and Nonstatutory 
         Stock Option Plan                        Incorporated by reference to
                                                  Exhibit 99 to the registrant's
                                                  Annual Report on Form 10-K
                                                  for the fiscal year ended
                                                  December 31, 1993.

(11)    Statement re Computation of Per 
        Share Earnings                                                       

(13)    Registrant's 1995 Annual Report to Shareholders                      

(20)    Registrant's Proxy Statement Dated March 22, 1996                    

(21)    Subsidiaries of Registrant                                           

(27)    Financial Data Schedule