EXHIBIT 21 SUBSIDIARIES OF GREAT-WEST LIFE & ANNUITY INSURANCE COMPANY SUBSIDIARIES OF GREAT-WEST LIFE & ANNUITY INSURANCE COMPANY JURISDICTION OF INCORPORATION OR ORGANIZATION SUBSIDIARY Benefits Communication Corporation (1) Delaware BenefitsCorp Equities, Inc. Delaware Confed Admin Services, Inc. Delaware Financial Administrative Services Corporation (2) Colorado First Great-West Life & Annuity Insurance Company New York Great-West Benefit Services, Inc. Delaware Great-West Realty Investments, Inc. Delaware Greenwood Property Corporation Colorado GW Capital Management, LLC Colorado GWL Properties, Inc. Colorado Maxim Series Fund, Inc. Maryland One Corporation Colorado One Health Plan of Arizona, Inc. Arizona One Health Plan of California, Inc. California One Health Plan of Colorado, Inc. Colorado One Health Plan of Florida, Inc. Florida One Health Plan of Georgia, Inc. Georgia One Health Plan of Illinois, Inc. Illinois One Health Plan of Indiana, Inc. Indiana One Health Plan of Massachusetts, Inc. Massachusetts One Health Plan of North Carolina, Inc. North Carolina One Health Plan of Ohio, Inc. Ohio One Health Plan of Oregon, Inc. Oregon One Health Plan of Tennessee, Inc. Tennessee One Health Plan of Texas, Inc. Texas One Health Plan of Washington, Inc. Washington One Orchard Equities, Inc. Colorado Orchard Capital Management, LLC Colorado Orchard Series Fund Delaware (1) Also doing business as Benefits Insurance Services, Inc. (2) Also doing business as Financial Administrative Services Corporation of Colorado.