<ARTICLE> 5 <CIK> 0000765880 <NAME> HEALTH CARE PROPERTY INVESTORS, INC. <MULTIPLIER> 1,000 <PERIOD-TYPE> YEAR <FISCAL-YEAR-END> DEC-31-1998 <PERIOD-END> DEC-31-1998 <CASH> 4,504 <SECURITIES> 0 <RECEIVABLES> 0 <ALLOWANCES> 0 <INVENTORY> 0 <CURRENT-ASSETS> 0 <PP&E> 1,322,060 <DEPRECIATION> 190,941 <TOTAL-ASSETS> 1,356,612 <CURRENT-LIABILITIES> 0 <BONDS> 621,045 <PREFERRED-MANDATORY> 0 <PREFERRED> 187,847 <COMMON> 30,987 <OTHER-SE> 376,585 <TOTAL-LIABILITY-AND-EQUITY> 1,356,612 <SALES> 0 <TOTAL-REVENUES> 161,549 <CGS> 0 <TOTAL-COSTS> 43,116 <OTHER-EXPENSES> 8,566 <LOSS-PROVISION> 0 <INTEREST-EXPENSE> 36,753 <INCOME-PRETAX> 87,167 <INCOME-TAX> 0 <INCOME-CONTINUING> 87,167 <DISCONTINUED> 0 <EXTRAORDINARY> 0 <CHANGES> 0 <NET-INCOME> 87,167 <EPS-PRIMARY> 2.56 <EPS-DILUTED> 2.54