As filed with the Securities and Exchange Commission on November 3, 2000
                                                     Registration No. 333-45118
================================================================================
                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549

                         POST EFFECTIVE AMENDMENT NO. 1
                                       TO
                                    FORM S-8
                             REGISTRATION STATEMENT
                                      Under
                           THE SECURITIES ACT OF 1933
                            ------------------------

                                PMC-SIERRA, INC.
             (Exact name of registrant as specified in its charter)


              Delaware                                     94-2925073
(State of Incorporation)                   (I.R.S. Employer Identification No.)


                       900 East Hamilton Avenue, Suite 250
                           Campbell, California 95008
                    (Address of principal executive offices)
                            ------------------------

             Quantum Effect Devices, Inc. 1999 Equity Incentive Plan
   Quantum Effect Devices, Inc. 1999 Non-Employee Directors Stock Options Plan
         Quantum Effect Devices, Inc. 1999 Employee Stock Purchase Plan
                            (Full title of the plan)

                            ------------------------

                          The Corporation Trust Company
                               1209 Orange Street
                           Wilmington, Delaware 19801
                                 (800) 677-3394
            (Name, address and telephone number of agent for service)

                            ------------------------
                                    Copy to:
                                   Neil Wolff
                        Wilson Sonsini Goodrich & Rosati
                            Professional Corporation
                               650 Page Mill Road
                        Palo Alto, California 94304-1050
                                 (650) 493-9300

                         CALCULATION OF REGISTRATION FEE
================= ============== ============ ==================== =============
                                   Proposed          Proposed
    Title of                       Maximum           Maximum           Amount
   Securities          Amount      Offering         Aggregate            of
     to be             to be      Price Per          Offering       Registration
 Registered (1)      Registered     Share             Price             Fee
- ----------------- -------------- ----------- -------------------- ------------
 Common Stock,
 $0.001 par value  1,965,715 (2)  $26.08 (2)  $ 51,265,847.20 (2)  $13,534.10
================= ============== =========== ==================== ============
 Common Stock,
 $0.001 par value  1,050,358 (3) $236.03 (3)  $247,915,998.74 (3)  $65,449.40
================= ============== =========== ==================== ============
Totals             3,016,073                  $299,181,845.94 (3)  $78,983.50(4)
================= ============== =========== ==================== ============

   (1) Pursuant  to the  Acquisition  Agreement  dated as of July 11, 2000 among
       PMC-Sierra, Inc. ("PMC"), Penn Acquisition Corp., Quantum Effect Devices,
       Inc.("QED"),  PMC assumed,  effective  as of August 24, 2000,  all of the
       outstanding  options to purchase  common  stock of QED under the QED 1999
       Equity Incentive Plan, the QED 1999  Non-Employee  Directors Stock Option
       Plan and the QED  1999  Employee  Stock  Purchase  Plan and such  options
       became  exercisable  to  purchase  shares  of PMC's  common  stock,  with
       appropriate  adjustments  to the number of shares and  exercise  price of
       each assumed option.
   (2) Options  granted  pursuant to an employee  stock option  plan.  Estimated
       pursuant to Rule 457(h)(1)  under the Securities Act of 1933, as amended,
       solely for the purpose of calculating the registration  fee. Based on the
       price per share at which the options may be exercised.
   (3) Shares reserved for future  issuance.  Estimated  pursuant to Rule 457(c)
       under the Securities  Act of 1933, as amended,  solely for the purpose of
       calculating  the  registration  fee. Based on the average of the high and
       low prices of the common  stock on August 31,  2000,  as  reported on the
       Nasdaq National Market.
   (4) Registration  fee previously  paid under original S-8 dated  September 1,
       2000
================================================================================


                                     PART II
               INFORMATION REQUIRED IN THE REGISTRATION STATEMENT


Item 3.    Incorporation of Documents by Reference.
           ---------------------------------------

         The following  documents and information are  incorporated by reference
as filed with the Securities and Exchange Commission:

1.       PMC's Annual Report on Form 10-K for the fiscal year ended December 26,
         1999, as amended, excluding Item 6 "Selected Financial Data" and Item 8
         "Financial   Statements  and   Supplementary   Data"  which  have  been
         superceded by information  contained in the sections of Amendment No. 1
         to PMC's Registration  Statement on Form S-4, dated July 26, 2000 (File
         No. 333-41878), that are incorporated by reference below;

2.       Of Amendment No. 1 to PMC's  Registration  Statement on Form S-4, dated
         July 26, 2000 (File No.  333-41878),  only the  following  sections are
         incorporated  herein by reference:  "Selected  Historical  Consolidated
         Financial Data of PMC" on pages 5 and 6, "PMC's financial condition and
         results of  operations"  on pages 51 and 52, and "PMC annual  financial
         statements" in Annex E.

3.       PMC's  Quarterly  Reports on Form 10-Q for the quarters  ended June 25,
         2000 and March 26, 2000; and

4.       PMC's Current  Reports on Form 8-K dated October 3, 2000,  September 1,
         2000,  August 28, 2000,  July 25, 2000,  July 12, 2000,  June 30, 2000,
         June 20, 2000, April 12, 2000, and March 20, 2000, as amended.

         All  documents  subsequently  filed by PMC pursuant to Sections  13(a),
13(c), 14 and 15(d) of the Securities Exchange Act of 1934, as amended, prior to
the filing of a  post-effective  amendment  which  indicates that all securities
offered  have been  sold or which  deregisters  all  securities  then  remaining
unsold,  shall be deemed to be  incorporated  by reference in this  registration
statement and to be part hereof from the date of filing such documents.

Item 4.  Description of Securities.
         -------------------------

         Not applicable.

Item 5.  Interests of Named Experts and Counsel.
         --------------------------------------

         Certain legal matters with respect to the shares will be passed upon by
Wilson,  Sonsini,  Goodrich & Rosati,  a  Professional  Corporation,  Palo Alto,
California.

Item 6.  Indemnification of Directors and Officers.
         -----------------------------------------

         Section 145 of the Delaware General  Corporation Law generally provides
that a  corporation  is empowered to indemnify any person who is made a party to
any threatened, pending or completed action, suit or proceeding by reason of the
fact that he is or was a director, officer, employee or agent of the corporation
or is or  was  serving,  at  the  request  of the  corporation,  in any of  such
capacities  of  another  corporation  or  other  enterprise,  if such  director,
officer,  employee  or agent  acted in good faith and in a manner he  reasonably
believed to be in or not opposed to the best interests of the corporation,  and,
with respect to any criminal  action or proceeding,  had no reasonable  cause to
believe his conduct was unlawful.  This statute describes in detail the right of
PMC to indemnify any such person.

         PMC's Certificate of Incorporation  eliminates in certain circumstances
the  liability  of  directors  of PMC for  monetary  damages for breach of their
fiduciary duty as directors.  This provision does not eliminate the liability of
a  director  (i) for  breach of the  director's  duty of  loyalty  to PMC or its
stockholders,  (ii) for acts or  omissions  by the director not in good faith or
which involve  intentional  misconduct or a knowing  violation of law, (iii) for
willful or negligent  declaration  of an unlawful  dividend,  stock  purchase or
redemption or (iv) for transactions  from which the director derived an improper
personal benefit.




         PMC's  Certificate  of  Incorporation   also  provides   generally  for
indemnification  of all  directors  and  officers of PMC to the  fullest  extent
permitted by the General Corporation Law of the State of Delaware. Such right to
indemnification  shall be deemed to be a contract  right and includes  generally
the right to be paid by PMC the expenses  incurred in defending  any  proceeding
covered by this provision in advance of its final  disposition.  Individuals who
are entitled to  indemnification  may bring suit to seek recovery of amounts due
under the  foregoing  provisions  and to recover  the  expenses  of such suit if
successful.

         PMC has entered into indemnification agreements to such effect with its
officers and directors containing  provisions which are in some respects broader
than  the  specific   indemnification   provisions   contained  in  the  General
Corporation  Law of Delaware.  The  indemnification  agreements may require PMC,
among other things,  to indemnify  such officers and directors  against  certain
liabilities  that may arise by reason of their status or service as directors or
officers (other than liabilities  arising from willful  misconduct of a culpable
nature) and to advance  their  expenses  incurred as a result of any  proceeding
against them as to which they could be indemnified.


         PMC believes that it is the position of the Commission  that insofar as
the  foregoing  provisions  may be invoked to  disclaim  liability  for  damages
arising under the Securities  Act, such  provisions are against public policy as
expressed in the Security Act and are therefore unenforceable.

         PMC currently maintains an officers' and directors' liability insurance
policy which covers,  subject to the exclusions  and  limitations of the policy,
officers and directors of PMC against certain  liabilities which may be incurred
by them solely in such capacities.

Item 7.  Exemption from Registration Claimed.
         -----------------------------------
         Not applicable.

Item 8.  Exhibits.
         --------

         The Exhibits to this registration  statement are listed in the Index to
Exhibits on page II-5.

Item 9.  Undertakings.
         ------------

           (a)    PMC hereby undertakes:

                  (1)      To file,  during any period in which  offers or sales
                           are being made,  a  post-effective  amendment to this
                           registration   statement   to  include  any  material
                           information  with respect to the plan of distribution
                           not   previously   disclosed   in  the   registration
                           statement or any material change to such  information
                           in the registration statement.

                  (2)      That,  for the purpose of  determining  any liability
                           under the  Securities  Act, each such  post-effective
                           amendment  shall be deemed  to be a new  registration
                           statement relating to the securities offered therein,
                           and the  offering  of such  securities  at that  time
                           shall be deemed to be the initial bona fide  offering
                           thereof.

                  (3)      To   remove   from    registration    by   means   of
                           post-effective  amendment any of the securities being
                           registered  which remain unsold at the termination of
                           the offering.

         (b) PMC  hereby  undertakes  that,  for  purposes  of  determining  any
liability  under the Securities Act, each filing of PMC's annual report pursuant
to Section  13(a) or Section 15(d) of the Exchange Act (and,  where  applicable,
each filing of an employee  benefit  plan's  annual  report  pursuant to Section
15(d) of the Exchange Act) that is incorporated by reference in the registration
statement  shall be deemed to be a new  registration  statement  relating to the
securities  offered  therein,  and the offering of such  securities at that time
shall be deemed to be the initial bona fide offering thereof.

         (c)  Insofar  as  indemnification  for  liabilities  arising  under the
Securities Act may be permitted to directors,  officers and controlling  persons
of PMC pursuant to the Delaware  General  Corporation  Law, the  Certificate  of
Incorporation  or the Bylaws of PMC,  Indemnification  Agreements  entered  into
between PMC and its officers and directors,  or otherwise,  PMC has been advised
that in the opinion of the  Commission  such  indemnification  is against public
policy as expressed in the Securities Act and is, therefore,  unenforceable.  In
the event that a claim for indemnification  against such liabilities (other than
the payment by PMC in the successful defense of any action,  suit or proceeding)
is asserted by such director,  officer or controlling  person in connection with
the securities being registered  hereunder,  PMC will,  unless in the opinion of
its counsel the matter has been settled by  controlling  precedent,  submit to a
court of appropriate  jurisdiction the question whether such  indemnification by
it is against  public  policy as  expressed  in the  Securities  Act and will be
governed by the final adjudication of such issue.





                                   SIGNATURES

         Pursuant to the  requirements of the Securities Act, PMC certifies that
it has reasonable  grounds to believe that it meets all of the  requirements for
filing on Form S-8 and has duly caused this Registration  Statement or amendment
thereto  to  be  signed  on  its  behalf  by  the  undersigned,  thereunto  duly
authorized, in New York, New York on this Novmeber 3, 2000.

                               PMC-SIERRA, INC.

                               By:  /s/ John Sullivan
                                   ------------------------------------
                                   John W. Sullivan
                                   Vice President, Finance (Principal Financial
                                   and Accounting Officer)


 Signature                      Title                                Date
- --------------------------------------------------------------------------------

/s/ ROBERT L. BAILEY*      President, Chief Executive Officer   October __, 2000
- --------------------       (Principal Executive Officer) and
Robert L. Bailey           Chairman of the Board of Directors


/s/ JOHN W. SULLIVAN       Vice President, Finance (Principal   October __, 2000
- --------------------       Financial and Accounting Officer)
John Sullivan

/s/ JAMES DILLER*          Director                             October __, 2000
- ----------------
James Diller

/s/ ALEXANDRE BALKANSKI*   Director                             October __, 2000
- -----------------------
Alexandre Balkanski

/s/ COLIN BEAUMONT*        Director                             October __, 2000
- ------------------
Colin Beaumont

/s/ FRANK J. MARSHALL*     Director                             October __, 2000
- ---------------------
Frank J. Marshall


*By: /s/ JOHN SULLIVAN
John Sullivan
Attorney-in-Fact






INDEX TO EXHIBITS


  Exhibit Number                 Description

      4.1+      Quantum Effect Devices, Inc. 1999 Equity Incentive Plan

      4.2+      Form of Stock  Option  Agreement  and Stock  Option Grant Notice
                under Quantum Effect Devices, Inc. 1999 Equity Incentive Plan

      4.3+      Quantum Effect Devices, Inc. 1999 Non-Employee  Directors' Stock
                Option Plan

      4.4+      Form of Stock  Option  Agreement  and Stock  Option Grant Notice
                under Quantum Effect Devices, Inc. 1999 Non-Employee  Directors'
                Stock Option Plan

      4.5+      Quantum Effect Devices, Inc. 1999 Employee Stock Purchase Plan

      4.6+      Form of Enrollment  Form and Grant of Right under Quantum Effect
                Devices, Inc. 1999 Employee Stock Purchase Plan

      5.1       Opinion  of  Wilson  Sonsini  Goodrich  &  Rosati,  Professional
                Corporation

     23.1       Consent of Deloitte & Touche LLP,  Vancouver,  British Columbia,
                Canada Independent Auditors

     23.2       Consent  of  Deloitte  &  Touche  LLP,  San  Jose,   California,
                Independent Auditors

     23.3+      Consent of Counsel (Contained in Exhibit 5.1 above)

     24.1+      Power of Attorney (see page II-4)

 + Previously filed