SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 8-K CURRENT REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Date of report (Date of earliest event reported) April 30, 2001 ________________________ IGENE Biotechnology, Inc. ________________________________________________ (Exact Name of Registrant as Specified in Charter) Maryland 0-15888 52-230461 ____________________________ _____________ ____________________________ (State of Other Jurisdiction (Commission (IRS Employer of Incorporation) File Number) Identification No.) 9110 Red Branch Road, Columbia, Maryland 21045 ____________________________________________________________ (Address of Principal Executive Offices)		(Zip Code) Registrant's telephone number, including area code 410-997-2599 ____________________ N/A ___________________________________________________________ (Former Name or Former Address, if Changed Since Last Report) Item 4. Changes in Registrant's Certifying Accountant On April 30, 2001, Igene Biotechnology, Inc., (the "Company") dismissed Berenson & Company, LLP ("Berenson") as its certifying accountant. Berenson performed the audit of the Company's financial statements for the years ended December 31, 2000 and 1999. During these periods and for the period from January 1, 2001 to April 30, 2001, there were no disagreements, whether or not resolved, between the Company and Berenson on any matter of accounting principles or practices, financial statement disclosure, or auditing scope or procedure, which, if not resolved to Berenson's satisfaction, would have caused Berenson to make reference to the subject matter of the disagreement(s) in connection with its audit reports on the Company's financial statements. For each of the years ended December 31, 2000 and 1999, Berenson issued audit reports on the Company's financial statements. Neither audit report contained an adverse opinion or disclaimer of opinion, or was modified as to audit scope or accounting principles. However, the audit reports for each of the years ended December 31, 2000 and 1999 were modified as to uncertainty about the Company's ability to continue as a going concern due to the Company's recurring losses and limited capitalization. On April 30, 2001, the Company engaged the firm of Stegman & Company ("Stegman") to audit the Company's financial statements for fiscal year 2001 as its certifying accountant. The decision to change accountants and appoint Stegman was recommended by the Audit Committee of the Board of Directors on April 27, 2001. There were no consultations between the Company and Stegman regarding the application of accounting principles to any matter, or as to any type of opinion that might be issued on the Company's financial statements. Item 7. Financial Statements, Pro Forma Financial Information and Exhibits (a) Financial Statements of Businesses Acquired Not applicable. (b) Pro Forma Financial Information Not applicable. (c) Exhibits (16) Letter of Berenson & Company, LLP pursuant to Item 304(q)(3) of Regulation SB - Filed herewith. Signatures Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized. IGENE Biotechnology, Inc. ______________________________________ (Registrant) Date April 30, 2001 By /s/ Stephen F. Hiu ________________________ ______________________________________ Stephen F. Hiu President and Treasurer Exhibit 16 - Letter of Berenson & Company, LLP [Letterhead of Berenson & Company, LLP] April 30, 2001 Securities and Exchange Commission Mail Stop 11-3 450 5th Street Washington, DC 20549 Dear Sirs/Madams: We have read and agree with the comments in the first paragraph as presented in Item 4 of Form 8-K of IGENE Biotechnology, Inc. dated April 30, 2001 ("Form 8-K"). We have no basis to agree or disagree with the comments in second and third paragraphs in Item 4 of the Form 8-K. Respectfully, /s/ Berenson & Company, LLP