UNITED STATES

               SECURITIES AND EXCHANGE COMMISSION

                     Washington, D.C. 20549

                           FORM 12b-25

                   NOTIFICATION OF LATE FILING

                Commission File Number: 000-15888

(Check One):  [ ]  Form 10-KSB  [ ]  Form 20-F  [ ]  Form 11-K
              [X]  Form 10-QSB  [ ]  Form N-SAR [ ]  Form N-CSR

                For Period Ended:   June 30, 2007

     [ ]  Transition Report on Form 10-K and Form 10-KSB
     [ ]  Transition Report on Form 20-F
     [ ]  Transition Report on Form 11-K
     [ ]  Transition Report on Form 10-Q and Form 10-QSB
     [ ]  Transition Report on Form N-SAR

     For the Transition Period Ended: ____________________



     Nothing  in this form shall be construed to imply  that  the
Commission has verified any information contained herein.

     If  the  notification  relates to a portion  of  the  filing
checked  above,  identify the item(s) to which  the  notification
relates:  ________________________________________________



                             PART I
                     REGISTRANT INFORMATION

     Full Name of Registrant:    IGENE BIOTECHNOLOGY, INC.

     Former Name if Applicable:  NA

     Address of Principal Executive Office:  9110 RED BRANCH ROAD

     City, State and Zip Code:   COLUMBIA, MARYLAND 21045-2024


                               -1-


                             PART II
                     RULES 12b-25(b) AND (c)

     If   the   subject  report  could  not  be   filed   without
unreasonable  effort or expense and the registrant  seeks  relief
pursuant  to  Rule 12b-25(b), the following should be  completed.
(Check box if appropriate.)

            (a)   The  reasons described in reasonable detail  in
                  Part III of  this  form could not be eliminated
                  without unreasonable effort or expense;

            (b)   The  subject annual report, semi-annual report,
                  transition  report  on  Form  10-K,  Form 20-F,
                  Form 11-K, Form N-SAR or Form N-CSR, or portion
                  thereof,  will  be  filed  on  or  before   the
     [ ]          fifteenth calendar day following the prescribed
                  due  date;  or the  subject quarterly report or
                  transition  report  on  Form  10-Q, or  portion
                  thereof  will  be filed on  or before the fifth
                  calendar day following the prescribed due date;
                  and

            (c)   The  accountant's statement  or  other  exhibit
                  required by Rule 12b-25(c) has been attached if
                  applicable.


                            PART III
                            NARRATIVE

     State  below in reasonable detail the reasons why the  Forms
10-K, 20-F, 11-K, 10-Q, N-SAR, N-CSR, or the transition report or
portion  thereof, could not be filed within the  prescribed  time
period.

          Additional  time will be needed for the  Registrant  to
     complete the preparation of its Quarterly Report on Form 10-
     QSB (the "Form 10-QSB") for the quarter ended June 30, 2007.
     The  Registrant  was  informed on August  10,  2007  by  its
     independent  accountant, J.H. Cohn ("Cohn"),  in  connection
     with  its  review  of  Form 10-QSB  that  they  required  an
     independent  valuation of warrants associated  with  certain
     debt.   The Registrant will require additional time to  file
     the  Form  10-QSB in order to prepare the warrant  valuation
     and  determine  whether  any  corresponding  revaluation  of
     related  debt instruments is material.  Prior to  completion
     of  this determination, the Registrant is unable to file and
     certify the Form 10-QSB.

          Based   upon   its  current  schedule,  the  Registrant
     anticipates  that it will not be in a position to  file  its
     Form 10-QSB by the 5th calendar day following the prescribed
     due date of the Form 10-QSB.

                               -2-



                             PART IV
                        OTHER INFORMATION

(1)  Name and telephone number of person to contact in regard to
     this notification.

     Edward J. Weisberger                         (410) 997-2599
     ___________________________________________________________
     (Name)                       (Area Code) (Telephone Number)

(2)  Have  all  other periodic reports required under Section 13
     or  15(d) of the Securities Exchange Act of 1934 or Section
     30  of  the  Investment  Company  Act  of  1940  during the
     preceding  12  months  or  for such shorter period that the
     registrant was required to file such report(s) been  filed?
     If answer is no, identify report(s).
                                              [X]  Yes   [ ]  No

(3)  Is it anticipated that any significant change in results of
     operations  from  the  corresponding  period  for  the last
     fiscal year will be reflected by the earnings statements to
     be included in the subject report or portion thereof?
                                              [X]  Yes   [ ]  No

     If so, attach an explanation of the anticipated change, both
     narratively  and quantitatively, and, if appropriate,  state
     the  reasons why a reasonable estimate of the results cannot
     be made.


     The Registrant cannot provide a reasonable estimate until a
     valuation is prepared, nor be sure if a  significant change
     will result.

                    Igene Biotechnology, Inc.
          ____________________________________________
          (Name of Registrant as Specified in Charter)

     Has caused this notification to be signed on its behalf  by
the undersigned thereunto duly authorized.



     Date: August 14, 2007       By: /s/ EDWARD J. WEISBERGER
                                     ___________________________
                                         Edward J. Weisberger
                                         Chief Financial Officer