SECURITIES AND EXCHANGE COMMISSION
                     WASHINGTON, D.C. 20549

                            Form 8-K

                         CURRENT REPORT

               PURSUANT TO SECTION 13 OR 15(d) OF
               THE SECURITIES EXCHANGE ACT OF 1934

Date of Report (Date of earliest event reported): January 28,
2008

                   IGENE BIOTECHNOLOGY, INC.
    ______________________________________________________
    (Exact Name of Registrant as Specified in its Charter)

                           Maryland
______________________________________________________________
(State or Other Jurisdiction of Incorporation or Organization)

        0-15888                           52-1230461
      ___________                     ___________________
      (Commission                      (I.R.S. Employer
        File No.)                     Identification No.)


  9110 Red Branch Road, Columbia, Maryland        21045-2024
  ________________________________________        __________
  (Address of Principal Executive Offices)        (Zip Code)

                        (410) 997-2599
     ____________________________________________________
     (Registrant's Telephone Number, Including Area Code)

                               N/A
 _____________________________________________________________
 (Former Name or Former Address, if Changed Since Last Report)


     Check the appropriate box below if the Form  8-K  filing  is
intended to simultaneously satisfy the filing obligation  of  the
registrant under any of the following provisions:

     [ ] Written communications pursuant to Rule  425  under  the
         Securities Act (17 CFR 230.425)

     [ ] Soliciting material pursuant to Rule  14a-12  under  the
         Exchange Act (17 CFR 240.14a-12)

     [ ] Pre-commencement  communications  pursuant  to Rule 14d-
         2(b) under the Exchange Act (17 CFR 240.14d-2(b))

     [ ] Pre-commencement  communications  pursuant to Rule  13e-
         4(c) under the Exchange Act (17 CFR 240.13e-4(c))



ITEM 4.02 Non-Reliance  on Previously Issued Financial Statements
          or a Related Audit Report or Completed Interim Review.

     On  September  27, 2007, we determined there were errors  in
the  Company's financial statements resulting from the accounting
for  warrants  issued with certain of our debt  obligations.  The
financial statements included in the Annual report on Form 10-KSB
for the year ended December 31, 2006 and the Quarterly report  on
Form  10-QSB for the three months ended March 31, 2007 (prior  to
the  restatement as discussed below) should no longer  be  relied
upon.

     The Company historically, when valuing the shares underlying
the  warrants of the Company, has applied a discount to the value
of  the  shares based on the illiquidity of the shares,  applying
blockage  discounts  to the value of the shares.   Based  on  the
application  of  illiquidity  discounts,  the  Company  initially
believed  that it would be an immaterial adjustment to  record  a
valuation to the shares underlying the warrants.

     However,  the  Company subsequently determined it needed  to
value  the shares underlying the warrants in connection with  the
Company's issuance of promissory notes and convertible debentures
using  a  Black  Scholes  model and ignoring  any  discounts  for
illiquidity  of  shares or blockage discounts.  The  Company  has
historically reported the warrants issued in connection with  the
Notes as having zero value and has not recognized any discount on
the Notes but rather recorded the full face value of the Notes as
Long   Term   Debt  in  its  consolidated  financial  statements.
Applying  the  Black Scholes model of valuation to the  warrants,
original issue discount is now applied to the Notes in an  amount
corresponding to the valuation of the warrants.

     As  a   result  of  the above, the Registrant  restated  the
financial statements included in its annual report on Form 10-KSB
for the year ended December 31, 2006, and the Form 10-QSB for the
three months ended March 31, 2007.

     The management of the Company and the Audit Committee of the
Board  of Directors of the Company discussed the matter contained
herein   with   the   Company's  independent  registered   public
accounting firm.


                            Signature

     Pursuant to the requirements of the Securities Exchange Act
of 1934, the registrant has duly caused this report to be signed
on its behalf by the undersigned hereunto duly authorized.

                              IGENE BIOTECHNOLOGY, INC.



                              By: /S/ STEPHEN F. HIU
                                  ______________________________
                                      STEPHEN F. HIU
                                      President



Date:  February 7, 2008