SCHEDULE 14A INFORMATION
   Proxy Statement Pursuant to Section 14(a) of the Securities
                      Exchange Act of 1934

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                     IGENE Biotechnology, Inc.
        ________________________________________________
        (Name of Registrant as Specified in Its Charter)

                              N/A
  ____________________________________________________________
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                           Registrant)

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                    IGENE BIOTECHNOLOGY, INC.
                      9110 Red Branch Road
                    Columbia, Maryland 21045

            Notice of Annual Meeting Of Stockholders
                   To Be Held November 3, 2008

     NOTICE  IS  HEREBY  GIVEN that the 2008  Annual  Meeting  of
Stockholders of IGENE Biotechnology, Inc. (the "Company", "we" or
"us")  will be held at the offices of Kimelman & Baird, LLC,  100
Park  Avenue, 21st floor, New York, New York 10017 at 10:00  a.m.
local time on November 3, 2008 for the following purposes:

     1.   To  elect five (5) directors to serve for a term of one
          (1) year  and  until  their  successors are elected and
          qualified.

     2.   To  authorize  and approve an amendment to the Articles
          of  Incorporation  to increase the number of authorized
          shares   of    common    stock   from   750,000,000  to
          3,000,000,000 shares.

     3.   To   approve the amendment to the Company's 2001  Stock
          Incentive  Plan  to  increase  the  number  of   shares
          available from 55,000,000 to 300,000,000.

     4.   To  transact  such  other business as may properly come
          before the meeting, or any adjournment thereof.

      Stockholders of record at the close of business on  October
3,  2008  shall  be entitled to notice of, and to  vote  at,  the
meeting.

      All  stockholders  are  cordially  invited  to  attend  the
meeting.

                              By order of the Board of Directors,



                              /S/   STEPHEN F. HIU
                              ___________________________________
                                    STEPHEN F. HIU
                                    President

Dated:    Columbia, Maryland
          October 3, 2008


     IMPORTANT: PLEASE FILL IN, DATE, SIGN AND MAIL PROMPTLY  THE
ENCLOSED  PROXY IN THE POSTAGE-PAID ENVELOPE PROVIDED  TO  ASSURE
THAT YOUR SHARES ARE REPRESENTED AT THE MEETING.


                               -1-


                    IGENE BIOTECHNOLOGY, INC.
                      9110 RED BRANCH ROAD
                    COLUMBIA, MARYLAND 21045

                         PROXY STATEMENT

     The  accompanying  proxy  is  solicited  by  the  Board   of
Directors  (or  the  "Board")  of IGENE  Biotechnology,  Inc.,  a
Maryland  corporation (the "Company", "we" or "us"), for  use  at
our 2008 Annual Meeting of Stockholders, which we refer to as the
"meeting,"  to  be held on November 3, 2008, or  any  adjournment
thereof.  Holders of record of our common stock, par value  $.01,
and  our  Series A, 8% Cumulative Preferred Stock (the "Series  A
preferred  stock"), at the close of business on October  3,  2008
(the  "record  date"), shall be entitled to vote at the  meeting.
Proposals  of stockholders intended to be presented at  our  2009
Annual  Meeting of Stockholders must be received by us  no  later
than  5:00  P.M. local time on March 1, 2009, to be eligible  for
inclusion in our proxy statement and form of proxy to be used  in
connection with such meeting.

     The cost of solicitation of proxies will be borne by us.  We
may  use  the services of our directors, officers, employees  and
others   to   solicit  proxies,  personally  or   by   telephone.
Arrangements  may  also be made with brokerage houses  and  other
custodians, nominees, fiduciaries and stockholders of  record  to
forward  solicitation material to the beneficial owners of  stock
held  of record by such persons. We may reimburse such solicitors
for  reasonable  out-of-pocket  expenses  incurred  by  them   in
soliciting, but no compensation will be paid for their services.

     Each  proxy  executed and returned by a stockholder  may  be
revoked  at  any time before it is voted by timely submission  of
written  notice of revocation or by submission of a duly executed
proxy  bearing  a  later date (in either  case  directed  to  our
Corporate Secretary at the above address) or, if a stockholder is
present  at the meeting, the stockholder may elect to revoke  his
or  her  proxy  by  voting his or her shares  in  person  at  the
meeting.

     There is being mailed herewith to each stockholder of record
our  Annual  Report  on  Form 10-KSB for the  fiscal  year  ended
December 31, 2007 and our Quarterly Report on Form 10-Q  for  the
quarter  ended  June  30,  2008.  The  notice,  proxy  statement,
enclosed form of proxy, Form 10-KSB and Form 10-Q will be  mailed
to  stockholders  of  record  beginning  October  3,  2008.   The
Company's website address is www.igene.com.

     On  the record date, there were 110,337,072 shares of common
stock  outstanding  and  entitled to vote  with  respect  to  all
matters  to be acted upon at the meeting. Each holder  of  common
stock is entitled to one vote for each share of common stock held
by such holder.

     On  the record date, we also had 11,134 shares of our Series
A  preferred stock outstanding and entitled to vote with  respect
to  all  matters to be acted upon at the meeting. Each holder  of
our  Series A preferred stock is entitled to two votes  for  each
share of Series A preferred stock held by such holder. Holders of
record  of  our outstanding shares of common stock and  Series  A
preferred  stock will be entitled to vote together  as  a  single
class on all matters to be voted on at the meeting.

     Pursuant to the terms of our Series A preferred stock, as  a
consequence  of  the non-payment of dividends on such  stock  for
more  than the past four consecutive dividend payment dates,  the
holders of Series A preferred stock, voting together as a  single
class,  are  entitled to elect two directors, in accordance  with
the  procedures  set forth in our Articles of  Incorporation,  as
amended  (the "Articles of Incorporation") and bylaws.  To  date,
the  holders  of the Series A preferred stock have not  exercised
such right.

Voting Procedures

     The  presence of holders representing a majority of all  the
votes entitled to be cast at the meeting will constitute a quorum
at  the  meeting.  In accordance with Maryland law,  abstentions,
but not broker non-votes, are counted for purposes of determining
the  presence  or  absence of a quorum  for  the  transaction  of
business.

                               -2-

     The  plurality of votes cast at the meeting is  required  to
elect  each of our director nominees under Proposal No.  1.   The
affirmative  vote  of  holders of  at  least  two-thirds  of  the
outstanding voting power of the Company entitled to  be  cast  at
the  meeting is required to approve Proposal No. 2, the amendment
to  the  Articles  of  Incorporation  increasing  the  number  of
authorized   shares  of  common  stock  to  3,000,000,000.    The
affirmative vote of holders of at least a majority of  the  votes
cast  on  Proposal No. 3 is required to approve the amendment  to
the  2001  Plan to increase the number of shares available  under
the 2001 Plan to 300,000,000.  The votes will be tabulated by the
Company's  Corporate Secretary.  Abstentions and broker non-votes
are not counted in determining the votes cast with respect to any
of the matters submitted to a vote of stockholders.

                         PROPOSAL NO. 1:
                      ELECTION OF DIRECTORS

     Pursuant  to our bylaws and as permitted by our Articles  of
Incorporation,  as  amended, the Board has fixed  the  number  of
directors  at  eight.  It is proposed to elect five directors  at
this  meeting to hold office for a one-year term, until the  2009
annual  meeting  of  stockholders,  and  until  their  respective
successors  are  duly  elected and qualified.   The  Company  has
recommended fewer nominees for directorships than have been fixed
by  the  Board under our bylaws, as the Board has determined  the
current nominees are appropriate at this time.  The Board has not
yet  determined whether to fill such vacancies and may reduce the
size  of  the  Board to eliminate one or more of  the  vacancies.
Proxies  cannot  be  voted for more than five  directors  at  the
meeting.  Each of the persons listed below has been nominated for
election to our Board at the meeting.  All of the nominees listed
below   presently  serve  on  our  Board.   If  some   unexpected
occurrence  should make necessary, in the Board's  judgment,  the
substitution  of  some other person or persons  for  any  of  the
nominees,  shares  for which proxies have been  granted  will  be
voted  for such other person or persons as the Board may  select.
The Board is not aware that any current director, or nominee, may
be  unable  or  unwilling to serve as a director.  The  following
table contains certain information with respect to the nominees:



                                  NOMINEES FOR ELECTION
                            

Name                     Age      Position with Igene
____                     ___      ___________________

Michael G. Kimelman       69      Chairman of the Board of
                                  Directors<F1>

Thomas L. Kempner         80      Vice Chairman  of
                                  the Board of Directors <F2>

Stephen F. Hiu            51      Director, President, Chief
                                  Technical Officer,
                                  and Director of Research and
                                  Development

Patrick F. Monahan        57      Director, Vice-President,
                                  Secretary, and Director
                                  of Manufacturing

Sidney R. Knafel          77      Director <F2>

<FN>

<F1>  Member of the audit committee of the Board of Directors.
<F2>  Member of the compensation committee of the Board of
      Directors.
</FN>


     Each of our directors was elected for a one-year term at the
Company's  most recent annual meeting, held in July of 2006,  and
because  no  annual  stockholder meeting was  held  in  2007,  is
currently holding-over from his prior term.

MICHAEL  G. KIMELMAN has served as a director of the Company  and
as Chairman of the Board of Directors since 1991.  At the time of
his  election  as director and through the present, Mr.  Kimelman
has  been  a  founder and member of Kimelman  &  Baird,  LLC,  an
investment advisory firm.  Mr. Kimelman also serves on the  board
and the executive committee of the Hambletonian Society.

                               -3-

THOMAS L. KEMPNER is Vice Chairman of the Board of Directors  and
has  been a director of the Company since its inception in  1981.
He  also  has been Chairman and Chief Executive Officer  of  Loeb
Partners  Corporation,  investment bankers,  New  York,  and  its
predecessors since 1978.  Mr. Kempner is currently a director  of
CCC Information Services Group, Inc., Dyax Corporation, Fuel Cell
Energy,  Inc.,  Insight Communications Co., Inc.,  Intermagnetics
General  Corp.  and Intersections, Inc.  He is  also  a  director
emeritus of Northwest Airlines, Inc.

STEPHEN F. HIU has served as Chief Technical Officer since  2002,
and  has  served as President and Treasurer of the Company  since
1999.   Mr. Hiu has served as a director since 1990 and has  been
the  Company's  Director of Research and Development  since  1989
and,  prior  thereto, was Senior Scientist since  he  joined  the
Company  in 1985.  Mr. Hiu was a post-doctoral Research Associate
at  the  Virginia  Polytechnic  Institute  and  State University,
Blacksburg, Virginia, from January 1984 until December 1985.  Dr.
Hiu  holds  a  Ph.D.  degree in microbiology  from  Oregon  State
University  and  a  B.S. degree in biological sciences  from  the
University of California, Irvine.

PATRICK  F.  MONAHAN has served as Vice-President of the  Company
since 2002, and as Director of Manufacturing and as a director of
the Company since 1991.  Mr. Monahan has also served as Secretary
of the Company since September 1998 and has managed the Company's
fermentation pilot plant since 1982.  He received an Associate of
Arts  degree  in biology from Allegheny Community College  and  a
B.S.  degree in biology with a minor in Chemistry from  Frostburg
State College, Frostburg, Maryland.

SIDNEY  R.  KNAFEL has served as a director of the Company  since
1982.   He  has  also  been Managing Partner  of  SRK  Management
Company,  a private investment company located in New York  City,
since  1981 and has served as Chairman of Insight Communications,
Inc.  since  1985.  Mr. Knafel is also currently  a  director  of
General American Investors Company, Inc., as well as a number  of
private companies.

 OUR BOARD OF DIRECTORS RECOMMENDS A VOTE "FOR" THE ELECTION OF
                 EACH OF THE DIRECTOR NOMINEES.

Committees of the Board of Directors

     We  have  two standing committees of the board of directors,
our  audit committee and our compensation committee.   We do  not
have  a  standing  nominating  committee.   Since  the  Board  of
Directors consists of five persons, each director participates in
the  consideration of director nominees.  Given the size  of  the
Company  and  its  resources, the Board  believes  that  this  is
appropriate.    The  Company  has not adopted  a  formal  process
relating  to  director nominations, nor does  it  have  a  formal
policy  regarding  the consideration of any  director  candidates
recommended  by  stockholders or specific minimum  qualifications
for  director  nominees.  The Board believes this is  appropriate
since any such recommendations may be informally submitted to and
considered  by the Company's directors.  Stockholders wishing  to
communicate  with  the  Board should  send  their  communications
addressed to the Board at the principal executive offices of  the
Company.  The Board periodically reviews the performance of  each
Board  member  and  concludes whether or not  the  member  should
continue in their current capacity.  Since the Company only has a
limited number of employees, it has not adopted a code of ethics.

     Set forth below is a description of the functions of each of
our standing committees and the members of the board of directors
who serve on such committees.

Audit Committee

     The   responsibilities  of  the  audit   committee   include
recommending to the board of directors the independent  certified
public  accountants to conduct the annual audit of our books  and
accounts, reviewing the proposed scope of the audit and approving
the  audit  fees to be paid. The audit committee is charged  with
reviewing, with the independent certified public accountants  and
with  our  management,  the  adequacy and  effectiveness  of  our
internal  auditing,  accounting  and  financial  controls.    Mr.
Kimelman  served  as  the  sole member  of  the  audit  committee
throughout  2007.  Mr. Kimelman is not independent as defined  in
Rule  4200(a)(15) of the Nasdaq Marketplace Rules, based  on  his
ownership percentage of the Company's securities.  Please see the
section  of  this proxy statement titled "Security  Ownership  of
Certain  Beneficial Owners and Management" for  more  information

                             -4-

about  Mr.  Kimelman's holdings.   The audit committee charter is
attached as Appendix II.  The  audit committee held four meetings
in 2007 to review the Company's 2006 audited financial statements
and three quarterly unaudited financial statements.

Audit Committee Report

     The  audit  committee has reviewed and discussed the  fiscal
year  2007 and 2006 audited financial statements with management,
and  has  discussed  with the independent  auditors  the  matters
required  to be discussed by the statement on Auditing  Standards
No.  61, as amended, "Communication With Audit Committees" issued
by  the  Auditing  Standards Board of the American  Institute  of
Certified   Public   Accountants  ("AICPA"),   as   modified   or
supplemented, and has received the written disclosures   and  the
letter   from   the  independent  auditors  required   by   AICPA
Independence   Standards  Board  Standard  No.  1   "Independence
Discussions  with Audit Committees," as modified or supplemented,
and  has  discussed  with the independent auditor  the  auditors'
independence.

     Based  on  the  review and discussions referred  to  in  the
previous paragraph, the audit committee recommended to the  board
of directors that the audited financial statements be included in
our  annual report on Form 10-KSB for the year ended December 31,
2007.

     Michael G. Kimelman, the sole member of the audit committee.

Compensation Committee

     Our  compensation committee is responsible for approving the
salaries of all of our officers and certain other employees.   It
also supervises the administration of all benefit plans and other
matters  affecting  executive compensation,  subject  to  further
approval  of  our  board  of  directors.    The  members  of  the
compensation committee during 2007 were Messrs. Thomas L. Kempner
and  Sidney  R.  Knafel.   The compensation  committee  held  one
meeting  during  2007  for the purposes of  considering  employee
share grants.  The compensation committee does not have a written
charter.   Compensation of executives and  directors  is  at  the
discretion of the compensation committee.

Director and Committee Independence

     Since the Company is not a listed company, it has determined
to  apply  Rule  4200(a)(15) of the Nasdaq Marketplace  Rules  to
determine independence of its directors.  Based on such rule, the
Company   has   determined  that  none  of  its   directors   are
independent. Accordingly, the members of the Company's audit  and
compensation committees are not independent.

Board of Directors Meetings and Compensation

      The board of directors held one meeting in 2007.   None  of
our  directors  attended fewer than 75% of the  total  number  of
meetings held by the board and by all committees of the board  on
which  he served during 2007.  Board members are encouraged,  but
not required, to attend our annual meeting of stockholders.  Four
directors attended our last annual meeting held in 2006.

                              -5-

Executive Officers

     Our  executive  officers are listed  blow,  in  addition  to
Messrs.  Hui  and  Monahan,  who are  listed  above  as  director
nominees.  Our officers serve at the discretion of the  Board  of
Directors  and until their respective successors are elected  and
qualified.

Name                         Age     Position with Igene
____                         ___     ___________________

Edward J. Weisberger         44      Chief Financial Officer

EDWARD J. WEISBERGER has served as Chief Financial Officer of the
Company since 2001.  He is a CPA with multiple years of financial
experience  in the public and private sectors with  both  smaller
and Fortune 100 companies.


Executive Compensation

     The  following tables show the compensation paid or  accrued
by  the  Company  to  each of the three executive  officers  (the
"named  executive officers"). Other than the 2001 Stock Incentive
Plan  and  the  401k Retirement Plan, the Company has  no  profit
sharing or incentive compensation plans.




                                 Summary Compensation Table

                                                                     All Other
Name and                                               Stock Awards  Compensation
Principal Position               Year   Salary($)<F1>  ($)           ($)<F2>        Total ($)
______________________________   ____   _____________  ____________  ____________   _________
                                                                     
Stephen Hiu                      2007   $ 153,886      $         0   $   6,396      $ 160,282
President
                                 2006     142,580                0       6,575        149,155

Patrick Monahan                  2007     137,914           10,000 <F3>  5,968        153,882
Vice-President, Secretary
and Director of Manufacturing    2006     129,965                0       5,838        135,803
Manufacturing

Edward Weisberger                2007     132,793                0       5,712        138,505
Chief Financial Officer
                                 2006     125,817                0       5,750        131,567

<FN>
<F1> Gross Salary of the named executive officers listed.

<F2> Includes annual taxable compensation for health insurance
     premium and employer match of 401(k).

<F3> Includes issuance of 1,000,000 shares of the Company's
     common stock at $.01 per share value based on current stock
     price in addition to restriction and blockage discounts.

</FN>

There are no employment agreements or arrangements, written or
unwritten, for any of the executive officers.


                               -6-

     Outstanding Equity Awards at Fiscal Year-End

     The  following  table sets forth information concerning  the
outstanding equity awards of each of the named executive officers
as  of December 31, 2007.  All options reflected on the table are
fully vested.




Name                Number of Securities
                    Underlying Unexercised    Option Exercise    Option Expiration
                    Options(#) Exercisable    Price ($/Share)    Date
___________         ______________________    _______________    _________________
                                                        
Stephen Hiu                2,000,000               $  .10           04/16/2008
                           2,000,000                  .05           01/19/2010
                              45,000                 .065           01/02/2011
                           4,800,000                 .025           08/13/2012
                           5,000,000                  .10           06/25/2014

Patrick Monahan            1,050,000                  .10           04/16/2008
                           1,317,500                  .05           01/19/2010
                           2,900,000                 .025           08/13/2012
                           2,000,000                  .10           06/25/2014

Edward Weisberger          2,500,000                  .05           12/01/2011
                             500,000                  .10           06/25/2014
                           1,500,000                 .027           12/09/2015



     Retirement Benefits

     There are no retirement benefits or any contracts, plans  or
arrangements, written or unwritten, that provide payment to named
executive   officers   in  connection  with  their   resignation,
retirement or other termination.

     Director Compensation

     During  2007, no directors were compensated for their  Board
or committee activities.


Security Ownership of Certain Beneficial Owners and Management

     The  following table sets forth information as of  September
9,  2008  with respect to beneficial ownership of shares  of  the
Company's  outstanding common stock by (i) each person  known  to
the Company to own or beneficially own more than five percent  of
its  common stock or preferred stock, (ii) each director  of  the
Company,  and  (iii) each named executive officer, and  (iv)  all
directors  and  executive officers as a group.  On  September  9,
2008  there  were 110,337,072 shares of common stock  issued  and
outstanding.   Shares  of  common stock  subject  to  options  or
warrants currently exercisable or exercisable within 60  days  of
September 9, 2008 are deemed outstanding for computing the  share
ownership  and percentage of the person holding such options  and
warrants,  but  are  not  deemed outstanding  for  computing  the
percentage  of any other person.  Unless otherwise  noted  below,
each  beneficial owner listed on the table below has sole  voting
and  investment  power with respect to their shares  beneficially
owned.   No shares of preferred stock are beneficially  owned  by
the persons listed below.

                             -7-



                                                   Common Stock
                                    ________________________________________
                                       Number of
Name and Address                       Shares                  Percent(%)
______________________              _______________          _______________

Directors and officers
______________________
                                                       
Stephen F. Hiu                       14,993,633<F1>          12.07
  9110 Red Branch Road
  Columbia, MD  21045

Thomas L. Kempner                   147,804,528<F2>          61.53
  61 Broadway
  New York, NY  10006

Michael G. Kimelman                  50,197,723<F3>          31.52
  100 Park Avenue
  New York, NY  10017

Sidney R. Knafel                    145,777,554<F4>          61.27
  810 Seventh Avenue
  New York, NY  10019

Patrick F. Monahan                    9,315,033<F5>           7.92
  9110 Red Branch Road
  Columbia, MD  21045

Edward J. Weisberger                  4,570,000<F6>           3.98
  9110 Red Branch Road
  Columbia, MD  21045

All Directors and Officers          372,658,471<F7>          84.25
  as a Group (6 persons)

Others
______

Joseph C. Abeles                     17,954,407<F8>          14.23
  220 E. 42nd Street
  New York, NY  10017

Fraydun Manocherian                   7,905,135<F9>           7.13
  3 New York Plaza
  New York, NY  10004

Fermic                               20,000,000<F10>         18.13
  Col. San Nicolas Tolentino
  Iztapalapa 09850 Mexico, D.F.

<FN>
<F1>   Includes 1,148,633 shares held directly or indirectly by Dr.
       Hiu and 13,845,000 shares issuable upon exercise of options held
       by Dr. Hiu that are currently exercisable.

                                  -8-

<F2>   Includes  17,933,110 shares held directly or indirectly  by
       Mr. Kempner and 536,920 shares issuable upon exercise of warrants
       held  by  Mr.  Kempner  that are currently  exercisable.   Also
       includes  43,800,135 shares issuable upon conversion  of  notes
       issued by the Company and held by Mr. Kempner.  Also includes (i)
       41,582,728 shares issuable upon exercise of warrants held by  a
       trust under which Mr. Kempner is one of two trustees and the sole
       beneficiary,  which are currently exercisable, (ii)  41,561,125
       shares issuable upon exercise of warrants held by a trust under
       which Mr. Kempner is one of two trustees and one of his brothers
       is the sole beneficiary, which are currently exercisable, (iii)
       2,079,411  shares  issuable upon exercise of warrants  held  by
       trusts under which Mr. Kempner is one of two trustees and is  a
       one-third beneficiary, that are currently exercisable, and (iv)
       311,099 shares issuable upon exercise of warrants held by trusts
       under  which  Mr.  Kempner  is  executor  and  is  a  one-third
       beneficiary, that are currently exercisable.  Mr. Kempner shares
       voting and investment power with respect to the shares listed in
       (i)-(iv) above.

<F3>   Includes 1,264,360 shares held directly or indirectly by Mr.
       Kimelman, and 14,000,000 shares issuable upon exercise of options
       that are currently exercisable.  Also includes 17,680,341 shares
       issuable upon the conversion of notes issued by the Company, and
       17,253,022  shares issuable upon exercise of warrants,  all  of
       which are held by Mr. Kimelman and are currently exercisable or
       convertible.

<F4>   Includes  18,190,551 shares held directly or indirectly  by
       Mr.  Knafel, 42,619,509 shares issuable upon the conversion  of
       notes issued by the Company and held by Mr. Knafel and 84,967,494
       shares  issuable  upon  the exercise of  warrants  directly  or
       beneficially owned by Mr. Knafel that are currently exercisable.

<F5>   Includes 2,047,533 shares held directly or indirectly by Mr.
       Monahan  and  7,267,500 shares issuable upon  the  exercise  of
       options held by Mr. Monahan that are currently exercisable.

<F6>   Includes 70,000 shares held directly by Mr. Weisberger  and
       4,500,000  shares  issuable upon exercise of options  that  are
       currently exercisable.

<F7>   Includes  42,863,601  shares of  common  stock,  39,612,500
       shares  issuable  upon exercise of options that  are  currently
       exercisable, 110,823,687 shares issuable upon the conversion of
       notes issued by the Company and 197,313,091 shares issuable upon
       the exercise of warrants that are currently exercisable.

<F8>   Includes 2,128,294 shares held directly or indirectly by Mr.
       Abeles, 6,723,701 shares issuable upon the conversion of $311,663
       of  long-term notes issued by the Company, and 9,102,412 shares
       issuable upon exercise of warrants held by Mr. Abeles that  are
       currently exercisable.

<F9>   Includes 7,375,935 shares of common stock owned directly or
       indirectly by Mr. Manocherian and 529,200 shares issuable  upon
       the  exercise of warrants owned directly or indirectly  by  Mr.
       Manocherian that are currently exercisable.

<F10>  Includes 20,000,000 shares of common stock held directly by
       Fermic.

</FN>


Compensation Committee Interlocks and Insider Participation

     Thomas  L. Kempner and Sidney R. Knafel are members  of  our
compensation committee. Neither Mr. Kempner nor Mr. Knafel is, or
has previously served as, one of our officers or employees.  None
of  our executive officers serve, or has served as member of  the
board  of directors or compensation committee of any other entity
that  has had one or more executive officers serving on our Board
or compensation committee.

                               -9-

Certain Relationships and Transactions

      In  order to provide the Company with sufficient  funds  to
settle  the litigation with the holders of the convertible  notes
issued  by the Company in 2001, on February 15, 2007, the Company
issued and sold an aggregate principal amount of $762,000  in  5%
convertible  debentures, $381,000 to each of Thomas  Kempner  and
Sidney  Knafel,  directors of the Company.  These debentures  are
convertible into shares of the Company's common stock at $.02 per
share  based on the offer made to the original debenture  holders
as the market price of the Company's common shares as of February
2007.   As  of  September 1, 2008 these debentures  have  accrued
$58,240 of interest, and no payments have been made.

      In order to provide the Company with working capital as the
inventory received from the termination of the joint venture with
Tate  &  Lyle PLC  is sold and the receivables are collected,  on
December  12,  2007,  the Company issued and  sold  an  aggregate
principal  amount of $300,000 in 8.5% secured notes, $150,000  to
each  of  Thomas  Kempner  and Sidney Knafel.   These  notes  are
secured  by  the  accounts receivable  of  the  Company.   As  of
September  1,  2008 these notes have accrued $10,850of  interest,
and no payments have been made.

      On  October  15,  2007, Mr. Monahan,  the  Company's  Vice-
President,  Secretary and Director of Manufacturing,  was  issued
1,000,000  shares  of  the  Company's  common  stock,  valued  at
$21,000, in connection with his employment with, and services to,
the Company.  The shares of common stock were issued pursuant  to
the  exemption from registration provided under Section  4(2)  of
the Securities Act of 1933, as amended.

      As  discussed in the section of this proxy statement titled
"Proposal   No.   2:  Amendment  to  Articles  of   Incorporation
Increasing  Authorized  Shares  of  Common  Stock,"  the  Company
intends  to commence an exchange offering to, among other things,
reduce  its  current debt, if Proposal No. 2 is approved  by  the
stockholders at the meeting.  Michael Kimelman, Chairman  of  the
Board,  and  Thomas Kempner and Sidney Knafel, directors  of  the
Company,  own  in  the aggregate $3,815,337 principal  amount  of
outstanding  non-convertible notes issued by  the  Company.   The
Company  expects that Messrs. Kimelman, Kempner and  Knafel  will
exchange  all  of  their  outstanding non-convertible  notes  for
shares  of  common  stock if the Company commences  the  exchange
offers.  In addition, Messrs. Kimelman, Kempner and Knafel own an
aggregate of $4,897,474 of outstanding notes convertible into  an
additional  734,369,671 shares of our common stock.  The  Company
expects  that  these convertible notes will be exchanged  on  the
same  terms  as the proposed exchange offers.  Directors  of  the
Company  own  warrants  and options to purchase  390,612,879  and
35,112,500  shares, respectively, of the Company's common  stock.
Officers of the Company own options to purchase 25,612,500 shares
of  the  Company's  common stock.  The Company expects  that  the
options  and warrants held by the directors and officers will  be
exchanged  for  shares of common stock in the  proposed  exchange
offers.

Section 16(a) Beneficial Ownership Reporting Compliance

     Based  solely on a review of the Section 16(a) reports filed
with  the  Securities  and Exchange Commission  (the  "SEC")  and
written  representations provided to the Company by its  officers
and  directors, and holders of more than ten percent of any class
of the Company's registered securities, the Company believes that
during  fiscal  year 2007, all filing requirements applicable  to
its  reporting officers, directors and greater than  ten  percent
beneficial  owners  were timely satisfied except  one  delinquent
Form 4 filing by Thomas L. Kempner resulting in four transactions
being  untimely  reported, and one delinquent Form  4  filing  by
Michael  Kimelman resulting in four transactions  being  untimely
reported.


                              -10-

Audit Fees and Services

     The  accounting firm of McElravy, Kinchen & Associates, P.C.
("McElravy")  has been engaged to audit the financial  statements
of  the Company for the fiscal year 2008.  McElravy served as the
Company's  registered public accountants to audit  the  financial
statements for 2007.  J.H. Cohn LLP ("Cohn") originally served as
the auditor in 2007 and served as the Company's registered public
accountants to audit the restated financial statements  in  2006.
Berenson  LLP originally served as the auditor in 2006;  however,
in May 2007, J.H. Cohn LLP acquired Berenson LLP in a transaction
that was structured as an asset sale.  Each of J.H. Cohn LLP  and
McElravy has advised the Company that neither the accounting firm
nor  any  of  its members or associates has any direct  financial
interest  in  or any connection with the Company  other  than  as
independent public auditors.

     As  of  January 11, 2008, the Company dismissed Cohn as  its
independent registered public accounting firm as approved by  the
audit  committee  of the Board of Directors.   The  audit  report
issued  by Cohn on the consolidated financial statements  of  the
Company as of and for the years ended December 31, 2006 and 2005,
included  in the Company's amended Annual Report on Form 10-KSB/A
filed on December 21, 2007, did not contain an adverse opinion or
a disclaimer of opinion, and was not qualified or modified, as to
uncertainty,  audit  scope or accounting  principles,  except  as
follows:

    Cohn's   report  contains  an  explanatory  paragraph.    The
    paragraph  states  that  the Company has  suffered  recurring
    losses  from  operations since inception and  has  a  working
    capital  deficiency that raises substantial doubt  about  its
    ability  to  continue  as a going concern.  The  consolidated
    financial  statements  do not include  any  adjustments  that
    might result from the outcome of that uncertainty.

     During  the  years ended December 31, 2006 and 2005 and  the
interim  period  through  January 11, 2008,  the  date  of  their
dismissal,  there have been no disagreements between the  Company
and  Cohn  on  any matter of accounting principles or  practices,
financial  statement disclosure, or auditing scope or  procedure,
which disagreements, if not resolved to the satisfaction of Cohn,
would  have  caused Cohn to make reference to the subject  matter
thereof  in  its report on  the Company's consolidated  financial
statements for such periods other than as described below.

     There  was  a  disagreement related to the Company's initial
accounting  for warrants issued in connection with  certain  debt
that  arose  in  connection with Cohn's review of  the  Company's
Quarterly  Report on Form 10-QSB for the quarterly  period  ended
June  30, 2007.  The accounting treatment was discussed with  the
audit  committee  of the Board of Directors and resolved  to  the
satisfaction  of  Cohn.  As a result, the  Company  restated  the
financial statements included in its Annual Report on Form 10-KSB
for the year ended December 31, 2006, and the Form 10-QSB for the
three  months  ended March 31, 2007.  The Company has  authorized
Cohn  to  respond  fully to the inquiries of  McElravy,  if  any,
concerning the matter.

     During  the  years ended December 31, 2006 and 2005 and  the
interim  period  through  January  11, 2008, Cohn did not  advise
the  Company  of any reportable event under Item 304(a)(1)(v)  of
Regulation  S-K other than in connection with their audit of  the
Company's  consolidated financial statements for the years  ended
December 31, 2006 and 2005, Cohn advised the Company's management
and  the  audit  committee of the Board  of  Directors  that  the
Company did not have the internal controls necessary for the non-
routine  recording of warrants issued in connection with  certain
of the Company's debt obligations.


                              -11-

     The  Company  appointed  McElravy  as  its  new  independent
registered  public accounting firm effective as  of  January  15,
2008.    The  selection  of McElravy was approved  by  the  audit
committee of the Board of Directors of the Company on January 15,
2008.

     The following table shows the aggregate fees paid or accrued
by  the  Company  for  the audit and other services  provided  by
McElravy  and J.H. Cohn LLP for fiscal year 2007, and  by  J.  H.
Cohn LLP for fiscal year 2006:




                                   FY 2007           FY 2006
                                   ________          ________
                                               
          Audit Fees               $ 33,000          $100,844
          Audit-Related Fees              0                 0
          Tax Fees                        0             5,000
          All Other Fees                  0                 0
                                   ________          ________

          TOTAL                    $ 33,000          $105,844



     Audit services provided by McElravy and Cohn for fiscal year
2007, and by Cohn for fiscal year 2006 consisted of the audit  of
the  consolidated financial statements and quarterly  reviews  of
financial  statements.   "Tax  Fees"  include  charges  primarily
related  to  tax return preparation and tax consulting  services.
In  2003,  the  SEC adopted a rule pursuant to the Sarbanes-Oxley
Act  of  2002  that,  except with respect to certain  de  minimis
services  discussed below, requires audit committee  pre-approval
of  audit  and  non-audit  services  provided  by  the  Company's
independent  auditors.   The  audit committee  reviews  and  pre-
approves audit and non-audit services of the independent auditors
in  conformity with the requirements of Sarbanes-Oxley.   All  of
the  2007 and 2006 services described above were pre-approved  by
the  audit committee pursuant to this SEC rule.  A representative
of  McElravy is expected to be available by phone at the  meeting
with  the  opportunity to make a statement if such representative
so desires and to respond to appropriate questions.


                         PROPOSAL NO. 2:
  AMENDMENT TO ARTICLES OF INCORPORATION INCREASING AUTHORIZED
                     SHARES OF COMMON STOCK.

     The  Company  is  proposing to amend Article  Fifth  of  its
Articles  of  Incorporation to increase the number of  authorized
shares   of  common  stock,  par  value  $.01  per  share,   from
750,000,000 shares to 3,000,000,000 shares.  Pursuant to  Article
Fifth  of its Articles of Incorporation, the Company is presently
authorized to issue 750,000,000 shares of common stock, of  which
on   the   record  date  110,337,072  shares  were   issued   and
outstanding. Approximately 488,414,337 of the Company's  unissued
shares  are  reserved  for issuance upon  exercise  of  presently
outstanding stock options, exercisable warrants and conversion of
convertible securities.  The Company is also presently authorized
to  issue 1,500,000 shares of Series A preferred stock, par value
$.01  per share, of which on the record date, 11,134 shares  were
issued  and  outstanding.   The authorized number  of  shares  of
Series  A  preferred stock will not change as the result  of  the
proposed amendment.

     The  Company is proposing (the "Proposal") to amend  Article
Fifth  of its Articles of Incorporation in order to increase  the
authorized  number of shares of common stock of the Company  from
750,000,000  shares to 3,000,000,000 shares, par value  $.01  per
share, as follows:

                              -12-

                          ARTICLE FIFTH

     The total number of shares of stock of all classes which the
Corporation has authority to issue is Three Billion, One  Million
Five  Hundred Thousand (3,001,500,000) shares divided into  Three
Billion  (3,000,000,000) shares par value of One Cent ($.01)  per
share  of  Common Stock, having an aggregate par value  of  Three
Hundred  Million Dollars ($300,000,000.00) and One  Million  Five
Hundred Thousand (1,500,000) shares of the par value of One  Cent
($.01) per share of Preferred Stock having an aggregate par value
of Fifteen Thousand Dollars ($15,000.00). The aggregate par value
of  all shares of stock is Three Hundred Million Fifteen Thousand
Dollars ($300,015,000.00).

     In  order  to reduce our stockholders' deficit,  reduce  our
debt,  improve our balance sheet ratios and simplify our  capital
structure,  we  are  proposing  to  commence  an  exchange  offer
pursuant to which we will offer to exchange shares of our  common
stock  for our outstanding notes due March 31, 2009, we are  also
proposing  to exchange common stock for and our other outstanding
convertible notes and warrants presently held by directors of our
Company.   Our directors own an aggregate of $3,815,337 principal
amount  of non-convertible notes, $4,897,474 principal amount  of
convertible  notes.  Directors of the Company  own  warrants  and
options   to   purchase   390,612,879  and   35,112,500   shares,
respectively,  of the Company's common stock.   Officers  of  the
Company  own  options  to  purchase  25,612,500  shares  of   the
Company's common stock.  The Company expects that these directors
and   officers  will  exchange  all  of  their  outstanding  non-
convertible  notes, convertible notes, options and  warrants  for
shares  of common stock in the exchange offers.  See the sections
of  this  proxy statement titled "Security Ownership  of  Certain
Beneficial Owners and Management" and "Certain Relationships  and
Transactions" for more information about the directors'  security
holdings and their interests in the proposed exchange offers.

     We  presently anticipate commencing the exchange offer after
the  date of this proxy statement, but before the scheduled  date
for  the  meeting; however, any such exchange offer will  not  be
consummated  until  after the date of the  meeting  and  will  be
contingent  upon  stockholder approval of the  amendment  of  the
Articles  of  Incorporation increasing the number  of  authorized
shares.  If stockholder approval is not obtained then we will not
effectuate  the exchange.  Any exchange offer will only  be  made
pursuant  to documents or arrangements made with the  holders  of
the securities to be exchanged.

     This  proxy statement shall not constitute an offer to  sell
or  the  solicitation of any offer to buy nor shall there be  any
sales   of   securities  in  any  state  in  which  such   offer,
solicitation  or sale would be unlawful prior to registration  or
qualification under the securities laws of any state.

     This   proposal  also  will  enable  the  Company  to   have
sufficient  shares of common stock to be issued or  reserved  for
issuance   to   provide  flexibility  with  respect   to   future
transactions, including financing requirements or other  business
transactions where the Company would have the option to  use  its
common  stock (or securities convertible into or exercisable  for
common  stock) as consideration (instead of, or in  addition  to,
cash)  in  connection  with future growth,  financing  and  other
corporate purposes.

     The  Board  of  Directors of the Company  has  approved  the
adoption  of the Proposal.  The Board of Directors believes  that
it is in the best interests of the Company to amend Article Fifth
of  the Articles of Incorporation to give effect to the Proposal.
In  order to adopt the Proposal, the affirmative vote of  holders
of  at  least two-thirds of the outstanding voting power  of  the
Company entitled to be cast at this meeting is required.

     Stockholders  of  the Company will not have  any  preemptive
rights  with  respect to the additional shares  of  common  stock
being  authorized.  No further approval by stockholders would  be
necessary  prior  to  the issuance of any  additional  shares  of
common  stock, except as may be required by law.   The  Board  of
Directors  has  sole  discretion to issue  additional  shares  of
common  stock for such consideration as may be determined by  the
Board  of  Directors.  The issuance of any additional  shares  of
common  stock  may have the effect of diluting the percentage  of
stock  ownership of the present stockholders of  the  Company  or
could,  under  certain circumstances, be construed  as  an  anti-
takeover effect.

                              -13-

     Directors  of  the Company who hold approximately 65% of the
outstanding voting power of the Company have indicated that  they
intend to vote all their shares in favor of the proposal to amend
the Articles of Incorporation of the Company.

 OUR BOARD OF DIRECTORS RECOMMENDS A VOTE "FOR" THE AMENDMENT TO
                 THE ARTICLES OF INCORPORATION.


                         PROPOSAL NO. 3:
AMENDMENT TO THE COMPANY'S 2001 STOCK INCENTIVE PLAN TO INCREASE
 THE NUMBER OF SHARES AVAILABLE FROM 55,000,000 TO 300,000,000.

     The Company is proposing to amend and restate its 2001 Stock
Incentive Plan (the "2001 Plan") to increase the number of shares
available  under  the  2001 Plan from 55,000,000  to  300,000,000
shares of common stock and to make certain other changes designed
to  reflect changes in regulatory requirements affecting the Plan
and  is  seeking  stockholder approval of such  amendment.   This
amendment  would  also  increase in  the  same  proportion,  from
5,500,000  to  30,000,000, the number of shares of  common  stock
that  may be allocated to the stock options or stock appreciation
rights  that are granted to any individual participant under  the
2001 Plan who is an employee during any single taxable year.  The
affirmative vote of a majority of the votes cast on the  proposal
to amend the 2001 Plan is required for approval of the amendment.
We  have attached as Appendix I to this proxy statement the  form
of  2001 Plan as it would be amended and restated to reflect  the
new  shares  authorized  for issuance  assuming  we  receive  the
stockholder approval we are requesting.

     The  purpose  of the 2001 Plan is to further the  long  term
stability and financial success of the Company by attracting  and
retaining  employees  through the use of stock-based  incentives,
and to provide employees of the Company with additional incentive
to   promote   the  success  of  the  Company.    The   following
description of the material terms of the 2001 Plan is intended as
a  summary only and is qualified in its entirety by reference  to
the  text  of  the 2001 Plan (reflecting the proposed  amendment)
attached as Appendix I.

Eligibility

     All  present and future employees of the Company1  that  the
Board  determines  have contributed or who  can  be  expected  to
contribute  significantly  to the Company  will  be  eligible  to
receive  incentive awards under the 2001 Plan.   The  approximate
number of persons eligible to participate in the 2001 Plan is  13
as of August 27, 2008.

     The  Board  has the power and complete discretion to  select
eligible employees to receive awards, and to determine the  type,
terms  and  conditions of the awards.  The Board may delegate  to
the  compensation committee, if any, the power  to  select  which
employees will receive awards, the type of awards, the time  when
awards  are  granted,  the  number  of  shares  of  common  stock
allocated to awards and the terms of awards, except to the extent
that  such  a delegation would prevent compliance with applicable
federal  securities  or  tax laws, or other  applicable  laws  or
regulations.   The  Board  may also  delegate  to  the  Executive
Committee  of  the  Company's  officers,  or,  if  the  Executive
Committee  ceases to exist, to the President of the Company,  the
authority to select eligible employees to receive stock  options,
to  determine  the time or times at which stock options  will  be
awarded  to  eligible employees and to determine  the  terms  and
conditions  of  such  stock options, subject to  compliance  with
applicable law.  Action taken by the Executive Committee  or  the
President pursuant to such a delegation must be ratified  by  the
Board.

Amount of Stock Available for Awards

     The number of shares of the Company's common stock available
for  incentive awards under the Company's 1997 Stock Option  Plan
and  2001  Plan  was 75,000,000, 10% of the total number  of  the
Company's  common  shares  authorized,  of  which 55,000,000  are
currently   authorized  under  the  2001  Plan.   The   remaining
20,000,000 shares were authorized under the Company's 1997  Stock
Option  Plan,  which  has  now expired.   The  number  of  shares
available  under the 2001 Plan, the option exercise  prices,  the
terms  of  incentive awards and the number of shares  subject  to
outstanding options are proportionately adjusted by the Board for
stock  dividends,  stock   splits,  re-capitalization,   mergers,

                               -14-

combinations of shares and other changes affecting  the Company's
common stock.   As  of September  9,  2008, there were 40,525,000
shares of  our  common  stock  subject to outstanding options and
restricted stock awards under the 2001 Plan. The Company proposes
to increase the number of shares available under the 2001 Plan to
300,000,000  to  maintain  the  10%  ratio to the total number of
shares of common stock  authorized  to  be issued by the Company.
The  Company's  common stock is quoted on the OTC Bulletin Board.
The  last quoted price of the Company's common stock on September
5, 2008 was $.013.

     The  actual amount of awards that will be granted under  the
2001 Plan after its amendment and restatement will depend upon  a
number  of  factors, including the market value of the  Company's
common  stock  on future dates, the achievement of  one  or  more
performance goals by the employees and actual performance of  the
Company.   Since  these factors are not known at this  time,  the
amount of awards paid under the 2001 Plan after its amendment and
restatement,  and the market value of such awards,  are  not  yet
determinable. In addition, because of these unknown variables, it
is  not possible to determine the benefits that might be received
by  recipients  under  the  2001 Plan  after  its  amendment  and
restatement.   The Summary Compensation Table  on  page  6  above
shows  the  awards  that were made in 2007 under  the  2001  Plan
(prior  to  its amendment and restatement proposed  herein).   No
awards  were  made  under the 2001 Plan in 2007 to  non-executive
directors.

Stock Options and Stock Appreciation Rights

     The Board may grant stock options to eligible employees, and
establish  the  terms  and conditions for exercising  each  stock
option.  Stock  options  may be either  incentive  stock  options
(which  are subject to favorable tax treatment under Section  422
of the Internal Revenue Code of 1986, as amended (the "Code")) or
non-qualified  stock  options (which are  not  entitled  to  such
treatment).   Stock  appreciation  rights  may  be  granted  with
respect  to  all  or  any part of a stock option,  and  also  are
subject  to  terms  and  conditions  set  by  the  Board.   Stock
appreciation  rights may be granted in connection  with  a  stock
option or in a separate incentive award.

     The  exercise price of a stock option granted to an employee
must  be  at least 100% of (i) the closing price of the Company's
common  stock on the date of determination if the stock is traded
on  a  national  securities exchange  or  quoted  on  the  Nasdaq
National  Market, (ii) the average of the closing bid  and  asked
prices  per share for the Company's common stock on the  date  of
determination  if the stock is not listed on a national  exchange
or  quoted  on  the Nasdaq National Market, or  (iii)  the  value
determined  by  the Board using the reasonable application  of  a
reasonable  valuation method if none of the above are  applicable
(the  "Fair  Market Value").  The exercise price of an  incentive
stock  option must be at least 110% of Fair Market Value  in  the
case  of a grant to an employee who is a 10% stockholder  of  the
Company.   The Fair Market Value of incentive stock options  that
become  exercisable  by an employee for the  first  time  in  any
calendar year is limited to $100,000.

      In  order  to  exercise a stock option,  an  employee  must
provide  the  Company with written notice and  pay  the  exercise
price  of  the stock option in full in cash, unless the terms  of
the  stock option agreement permit the employee to deliver mature
shares  (shares  of common stock to which the employee  has  good
title, free and clear of all liens, which the employee has either
held  for  at least six months or purchased on the open  market),
valued at their Fair Market Value, in satisfaction of all or  any
part  of  the exercise price. Alternatively, an employee's  stock
option  agreement may permit the employee to conduct  a  "broker-
assisted" exercise.  A broker-assisted exercise occurs  when  the
employee  delivers the exercise notice, together with irrevocable
instructions to a broker to deliver to the Company, from the sale
or loan proceeds with respect to the sale of common stock that is
the  subject of the stock option or from a loan secured by common
stock  that  is  the  subject of the  stock  option,  the  amount
necessary to pay the exercise price and, if required by the terms
of the stock option, any applicable withholding taxes.

      Stock options may be exercised in whole or in part at  such
times  as  may  be  specified  in  the  employee's  stock  option
agreement,  subject  to  certain  limitations  with  respect   to
incentive  stock  options.   No incentive  stock  option  may  be
exercised after the first to occur of (x) ten years from the Date
of  Grant  (or  five years if the employee is a 10% shareholder),
(y)  three months following the date of the employee's retirement
or  termination of employment with the Company for reasons  other
than  disability or death, or (z) one year following the date  of
the employee's termination of employment on account of disability
or  death  (or, if the employee dies after terminating employment
while  the  option is still exercisable, one year  following  the
date of the employee's death).

                               -15-

     The Board may grant a stock appreciation right in connection
with all or any part of a stock option or as a separate award.  A
stock  appreciation  right entitles the employee  to  receive  an
amount  equal to the excess of (i) the Fair Market Value  of  the
common  stock covered by the stock appreciation right  over  (ii)
the  Fair  Market Value of the common stock on the  date  of  the
stock  appreciation  right was granted.  The  stock  appreciation
right can be paid in stock or cash, or both.

Restricted Stock

     The  Board  may also grant shares of common stock  that  are
subject  to certain terms and conditions.  Employees who  receive
restricted  stock  may not sell or transfer the restricted  stock
until the restrictions have been met, and if the restrictions are
not met, the restricted stock will be forfeited. Unless otherwise
provided  in  the  restricted  stock agreement,  a  stockholder's
agreement  or  any other agreement, a holder of restricted  stock
will  have  all the rights of a Company stockholder  holding  the
same class or series of common stock, including the right to vote
the shares and the right to receive dividends and distributions.

Federal Income Tax Consequences

     The  following is a brief and general summary of the federal
income tax consequences of transactions under the 2001 Plan based
on  federal  income tax laws in effect on January  1,  2008.  The
summary does not purport to be complete, and does not address the
tax consequences of a participant's death or the state, local and
foreign  tax  laws  that  may also be applicable  to  awards  and
transactions involving awards.

     A  participant generally will not incur federal  income  tax
when  he  or  she  is  granted a nonqualified  stock  option,  an
incentive  stock  option  or a stock  appreciation  right.   Upon
exercise  of  a nonqualified stock option or a stock appreciation
right,  the participant will be treated in most circumstances  as
having  received ordinary income equal to the difference  between
the  fair  market value of the common stock on the  date  of  the
exercise and the exercise price.

      This  income  is subject to income tax withholding  by  the
Company.  When a participant exercises an incentive stock option,
he or she generally will not recognize taxable income, unless the
participant is subject to the alternative minimum tax, subject to
satisfying applicable holding period requirements.

     A  participant will generally not incur federal  income  tax
when he or she is granted restricted stock. When the restrictions
imposed  on the restricted stock lapse, the participant  will  be
treated  as  having received ordinary income equal  to  the  fair
market value of the restricted stock on the date the restrictions
lapsed. A participant may make a special election under the  Code
to  be taxed on the fair market value of the restricted stock  at
the time the restricted stock is granted.  If such an election is
made,  the  participant  generally will not  be  taxed  when  the
restrictions   on  the  restricted  stock  later  lapse.   Income
recognized  by a participant in connection with restricted  stock
is subject to income tax withholding by the Company.

     The  Company usually will be entitled to a business  expense
deduction at the time and in the amount that the recipient of  an
award  recognizes ordinary income. As stated above, this  usually
occurs  upon  exercise of nonqualified stock  options  and  stock
appreciation  rights,  and  upon the  lapse  of  restrictions  on
restricted stock. No deduction is allowed in connection  with  an
incentive stock option unless the employee disposes of the common
stock  received  upon exercise in violation  of  certain  holding
period requirements.  There may be circumstances when a deduction
is  not allowed for certain transfers of common stock or payments
to  participants  upon the exercise of an  award  that  has  been
accelerated  as a result of a change of control.   Also,  Section
162(m)  of  the Code imposes a $1,000,000 limit on the amount  of
the  annual  compensation deduction allowable to a  publicly-held
company with respect to its PEO and each of its other three  most
highly compensated officers (other than the PFO), and the Company
will not be able to deduct the payment of compensation to any  of
these persons in excess of the $1,000,000 annual limit unless  it
qualifies for an applicable exclusion

                              -16-

     The  discussion above is subject to the general federal  tax
doctrines of constructive receipt and economic benefit and to the
applicable provisions of Code Section 409A.  If at any  time  the
2001  Plan,  any  incentive award under the  2001  Plan,  or  any
arrangement required to be aggregated with the 2001 Plan  or  any
incentive  award  under the 2001 Plan fails to  comply  with  the
applicable  requirements  of  Code  Section  409A,  all   amounts
(including  earnings) deferred under the 2001 Plan or  the  award
for  the  taxable  year and all preceding taxable  years  by  any
participant  with  respect  to  whom  the  failure  relates   are
includible  in  that participant's gross income for  the  taxable
year,  to the extent the amounts are not subject to a substantial
risk  of forfeiture and have not previously been included in  the
participant's gross income.  These amounts are also subject to an
additional  income  tax  equal to twenty percent  of  the  amount
required to be included in gross income and to interest equal  to
the  underpayment rate specified by the Internal Revenue  Service
plus  one  percentage  point, imposed on the  underpayments  that
would  have occurred had the compensation been included in income
for  the  taxable year when first deferred, or if later, when  no
longer subject to a substantial risk of forfeiture.

Administration

     The Board of Directors administers the 2001 Plan.  The Board
may,  however, delegate the responsibility for administering  the
2001  Plan  to the compensation committee of the Board,  provided
the  compensation  committee  consists  solely  of  non-employee,
outside  directors, as defined in Section 162(m) of the Code  and
Rule 16b-3 of the Exchange Act of 1934, as amended (the "Exchange
Act").   The 2001 Plan may be terminated, modified or amended  by
the stockholders of the Company.  The Board of Directors may also
terminate the 2001 Plan or modify or amend it in certain respects
as set forth in the 2001 Plan.

Plan Amendment and Termination

     The  Board  may  amend or terminate the 2001  Plan  in  such
respects  as  it shall deem advisable; however, if  the  Code  so
requires,  no change may be made that increases the total  number
of  shares  of  common  stock reserved for issuance  pursuant  to
incentive   awards  granted  under  the  2001  Plan  (except   in
connection with a business combination, re-capitalization,  stock
dividend  or  combination and the like), materially modifies  the
requirements  as  to eligibility for participation  in  the  2001
Plan,   or   materially  increases  the  benefits   accruing   to
participants under the 2001 Plan, unless the change is authorized
by  the  stockholders  of the Company.  The Board  may,  however,
amend the 2001 Plan and unilaterally amend incentive awards under
the  2001 Plan as it deems appropriate to ensure compliance  with
applicable  federal or state securities laws or  regulations,  or
any applicable NASDAQ or securities exchange listing requirement,
or to cause incentive stock options issued under the 2001 Plan to
meet  the  requirements  of the Code and applicable  regulations.
Except as indicated in this paragraph, a termination or amendment
of   the  2001  Plan  will  not,  without  the  consent  of   the
participant, detrimentally affect the participant's rights  under
an  incentive  award previously granted to the participant.   The
2001 Plan will terminate automatically on April 30, 2011.


 OUR BOARD OF DIRECTORS RECOMMENDS A VOTE "FOR" THE AMENDMENT OF
                 THE 2001 STOCK INCENTIVE PLAN.

Stockholder Proposals

     Any  stockholder  desiring  to present  a  proposal  to  the
stockholders at the 2009 Annual Meeting of Stockholders  and  who
desires  that  the  proposal  be  included  the  Company's  proxy
statement and proxy card relating to that meeting, must  transmit
the  proposal  to  the Secretary of the Company  so  that  it  is
received  at the Company's principal executive offices  no  later
than  5:00 p.m. local time on March 1, 2009.  All proposals  must
comply   with  applicable  SEC  regulations.  With   respect   to
stockholder  proposals  that  are  not  included  in  the   proxy
statement  for  the  2008  Annual Meeting  of  Stockholders,  the
persons  named in the proxy solicited by the Company's  board  of
directors  for  the 2008 Annual Meeting of Stockholders  will  be
entitled to exercise discretionary voting power conferred by  the
proxy  under  circumstances specified in Exchange Act  Rule  14a-
4(c), including with respect to proposals received by the Company
after  August  10,  2008. It is suggested that  the  proposal  be
submitted  by  certified mail, return receipt requested,  to  our
principal  executive  office  at  the  following  address:  IGENE
Biotechnology,  Inc.,  9110 Red Branch Road,  Columbia,  Maryland
21045, Attn:  Corporate Secretary.

                              -17-

Deliver to Stockholders Sharing Address

     We  are providing a copy of our Annual Report on Form 10-KSB
for  the  fiscal year ended December 31, 2007 and  our  Quarterly
Report  on  Form  10-Q  for  the  quarter  ended  June  30,  2008
simultaneously  with delivery of this Proxy  Statement.  You  may
obtain  additional  copies of the proxy  statement,  Form  10-KSB
and/or  Form  10-Q  filed  with  the  SEC  by  writing  to  IGENE
Biotechnology,  Inc.,  9110 Red Branch Road,  Columbia,  Maryland
21045, Attn:  Corporate Secretary or by calling (410) 997-2599.

     We  are delivering only one proxy statement, Form 10-KSB and
Form  10-Q to multiple stockholders sharing an address unless  we
have  received  contrary instructions from one  or  more  of  the
stockholders.  We  will promptly deliver  upon  written  or  oral
request a separate copy of this proxy statement, the Form  10-KSB
or the Form 10-Q to a stockholder at a shared address to which  a
single  copy  was sent. If you are a stockholder  residing  at  a
shared  address and would like to request an additional  copy  of
the proxy statement, Form 10-KSB or Form 10-Q now or with respect
to future mailings, or to request to receive only one copy of the
proxy  statement, Form 10-KSB or Form 10-Q if you  are  currently
receiving  multiple  copies, please send your  request  to  IGENE
Biotechnology,  Inc.,  9110 Red Branch Road,  Columbia,  Maryland
21045, Attn:  Corporate Secretary or call (410) 997-2599.

Other Business

     At  the date of this proxy statement, the only business that
the  board  of directors intends to present or knows that  others
will  present at the meeting is that hereinabove set  forth.   If
any  other  matter  or matters are properly  brought  before  the
meeting, or any adjournment thereof, it is the intention  of  the
persons named in the accompanying form of proxy to vote the proxy
on such matters in accordance with their judgment.

INCORPORATION BY REFERENCE

     The  SEC allows us to "incorporate by reference" information
into  this  proxy  statement. This means  that  we  can  disclose
important information about us and our financial condition to you
by  referring you to another document filed separately  with  the
SEC.  The information incorporated by reference is considered  to
be   part   of   this  proxy  statement.  This  proxy   statement
incorporates  by reference the information listed below  that  we
have  previously filed with the SEC. We incorporate by  reference
Items  6, 7 and 8 from Part II of the Company's Annual Report  on
Form  10-KSB  for the fiscal year ended December  31,  2007,  and
Items  1  and 2 from Part I of the Company's Quarterly Report  on
Form  10-Q for the quarterly period ended June 30, 2008  and  any
other items in that Quarterly Report expressly updating the above
referenced items from our Annual Report on Form 10-KSB.  You  can
read  and obtain copies of the information incorporated into this
proxy statement at the following SEC location:

                      Public Reference Room
                       100 F Street, N.E.
                     Washington, D.C. 20549

     You  may  obtain information on the operation of the  Public
Reference Room by calling the SEC at (800) SEC-0330. The SEC also
maintains  a  web  site that contains reports, proxy  statements,
information statements and other information about issuers,  like
IGENE Biotechnology, Inc., who file electronically with the  SEC.
The address of that web site is www.sec.gov.



                        /S/ STEPHEN F. HIU
                        _________________________________________
                            STEPHEN F. HIU
                            President and Chief Technical Officer

<PAGE<

                                                       APPENDIX I

                    IGENE BIOTECHNOLOGY, INC.

         AMENDED AND RESTATED 2001 STOCK INCENTIVE PLAN


     1.   PURPOSE.
          _______

          The  purpose  of  the  Amended  and Restated 2001 Stock
Incentive  Plan  (the  "Plan")  is  to  further  the  long   term
stability and financial success of IGENE Biotechnology, Inc.  and
its subsidiaries (collectively the "Company") by  attracting  and
retaining  employees  through the use of stock-based  incentives,
and  to provide employees with an additional incentive to promote
the  success  of the Company.  It is believed that  ownership  of
Company  Common  Stock  will  stimulate  the  efforts  of   those
employees  upon whose judgment and interests the Company  is  and
will  be  largely  dependent for the successful  conduct  of  its
business.   It is also believed that Incentive Awards granted  to
employees under this Plan will strengthen their desire to  remain
employed with the Company and will further the identification  of
employees'  interests  with those of the Company.   The  Plan  is
intended  to  operate  in  compliance  with  the  provisions   of
Securities and Exchange Commission Rule 16b-3.

     2.   DEFINITIONS.
          ___________

          As  used  in  the  Plan,  the  following terms have the
meanings indicated:

(a)  "ACT" means the Securities Exchange Act of 1934, as amended.

(b)  "APPLICABLE WITHHOLDING TAXES" means the aggregate amount of
     federal,  state  and local income and payroll taxes that the
     Company  is  required  by  applicable  law  to   withhold in
     connection  with  any  lapse  of  restrictions on Restricted
     Stock  or  any  exercise  of  a Nonstatutory Stock Option or
     Stock Appreciation Right.

(c)  "BOARD" means the Board of Directors of IGENE Biotechnology,
     Inc.

(d)  "CHANGE  OF  CONTROL"  means  the  occurrence  of any of the
     following events:

          (i)  The acquisition by a Group of Beneficial Ownership
     of  50%  or  more of the Common Stock or the Voting Power of
     the  Company,  but  excluding  for  this  purpose:   (A) any
     acquisition by the Company (or a Subsidiary of the Company),
     or  an  employee  benefit  plan  of  the  Company;   (B) any
     acquisition  of  Common  Stock of the Company  by management
     employees of the Company; (C) any acquisition by a member or
     members  of  the  Board  who  own  Common  Stock  as  of the
     effective  date  specified  in  Section  11  (the  "Existing
     Shareholders");     or  (D)  any  trusts,  partnerships   or
     corporations controlled by the Existing Shareholders.

         (ii)  Individuals  who  constitute the Board on the date
     immediately after the effective date set forth in Section 11
     (the  "Incumbent  Board")  cease  to  constitute  at least a
     majority  of  the  Board,  provided  that any director whose
     nomination was approved by a majority of the Incumbent Board
     shall  be  considered a member of the Incumbent Board unless
     such  individual's  initial  assumption  of  office  is   in

     connection with an actual or threatened election contest (as
     such  terms  are  used  in  Rule  14a-11  of  Regulation 14A
     promulgated under the Act).

        (iii)  Approval  by  the shareholders of the Company of a
     reorganization,  merger  or consolidation,  in each case, in
     which  the  owners  of  more than 50% of the Common Stock or
     Voting  Power  of  the  Company  do   not,  following   such
     reorganization,  merger  or consolidation, beneficially own,
     directly or indirectly, more than 50% of the Common Stock or
     Voting  Power  of  the  corporation  resulting   from   such
     reorganization, merger or consolidation.

         (iv)  A  complete  liquidation  or  dissolution  of  the
     Company  or  a  sale  or   other   disposition  of  all   or
     substantially all of the Company's assets.

(e)  "CODE" means the Internal Revenue Code of 1986, as amended.

(f)  "COMMITTEE"  means  the Compensation Committee of the Board,
     provided  that  each  member  of  the Compensation Committee
     qualifies  as  an  outside  director  for  purposes  of Code
     section 162(m), a non-employee director for purposes of Rule
     16b-3  and  an  independent  director  for  purposes  of the
     listing  standards  of  the NASDAQ or securities exchange on
     which the Common Stock may be listed.

(g)  "COMMON STOCK"  means  common  stock of IGENE Biotechnology,
     Inc., par value $.01 per share.  In the event of a change in
     the  capital  structure  of  IGENE  Biotechnology, Inc.  (as
     provided in  Section  13),  the shares resulting from such a
     change shall be deemed to be Common Stock within the meaning
     of the Plan.

(h)  "COMPANY"  means  IGENE  Biotechnology,  Inc.  and,  as  the
     context requires, its Subsidiaries.

(i)  "DATE  OF  GRANT"  means  (i) with respect to a Nonstatutory
     Stock  Option, the date on which the Committee completes the
     corporate action necessary to create a legally binding right
     constituting  the  Nonstatutory Option; or (ii) with respect
     to  an  Incentive  Stock  Option,  the  date  on  which  the
     Committee  completes  the  corporate  action constituting an
     offer  of  stock for sale to an employee under the terms and
     conditions  of  the  Incentive  Stock Option; and (iii) with
     respect  to  Restricted  Stock,  the date on which the Board
     grants  the  Incentive  Award.  With respect to an Incentive
     Award, the Committee may specify a future date on which  the
     grant is to be granted or become effective.

(j)  "DISABILITY"  or  "DISABLED" means, as to an Incentive Stock
     Option,  a  disability  within  the  meaning of Code section
     22(e)(3).  As to all other Incentive Awards, the Board shall
     determine whether a Disability exists and such determination
     shall be conclusive.

(k)  "FAIR  MARKET  VALUE"  means, as of any date, the value of a
     share of Common Stock, determined as follows:

          (i) if such Common Stock is  then  quoted on the NASDAQ
     National  Market,  its  closing price on the NASDAQ National
     Market on the date of determination, as reported in The Wall
     Street Journal;

         (ii) if  such  Common Stock is then listed on a national
     securities  exchange,  its  closing  price  on  the  date of
     determination on the principal  national securities exchange
     on which the Common Stock is  listed or admitted to trading,
     as reported in The Wall Street Journal;

        (iii) if  such  Common  Stock is not quoted on the NASDAQ
     National  Market  nor  listed  or  admitted  to trading on a
     national securities exchange, the average of the closing bid
     and  asked  prices on the date of determination, as reported
     in  The  Wall  Street Journal or by such other source as the
     Board may determine to be reliable;

         (iv) if  none  of  the  foregoing  is applicable, by the
     Board  using  the  reasonable  application  of  a reasonable
     valuation method.

(l)  "INCENTIVE   AWARD"  means,  collectively,   an   award   of
     Restricted  Stock, an Option, or a Stock Appreciation  Right
     granted under the Plan.

(m)  "INCENTIVE  STOCK  OPTION"  means an Option intended to meet
     the  requirements  of,  and  qualify  for  favorable federal
     income tax treatment under, Code section 422.

(n)  "MATURE  SHARES"  means shares of Common Stock for which the
     holder  thereof  has good title, free and clear of all liens
     and  encumbrances  and which such holder either (i) has held
     for  at  least six months, or (ii) has purchased on the open
     market.

(o)  "NONSTATUTORY  STOCK  OPTION"  means an Option that does not
     meet  the  requirements  of  Code  section  422, or, even if
     meeting  the  requirements  of  Code  section  422,  is  not
     intended  to  be  an  Incentive  Stock  Option  and  is   so
     designated.

(p)  "OPTION"  means  a  right  to  purchase Common Stock granted
     under the Plan, at a price determined in accordance with the
     Plan.

(q)  "PARTICIPANT" means any employee of the Company who receives
     an Incentive Award under the Plan.

(r)  "RESTRICTED STOCK" means Common Stock awarded upon the terms
     and subject to the restrictions set forth in Section 10.

(s)  "RULE 16B-3" means Rule 16b-3 of the Securities and Exchange
     Commission  promulgated  under  the  Act. A reference in the
     Plan  to  Rule  16b-3  shall  include  a  reference  to  any
     corresponding   rule   (or  number  redesignation)  of   any
     amendments to Rule 16b-3 enacted after the effective date of
     the Plan's adoption.

(t)  "STOCK  APPRECIATION RIGHT" means a right to receive amounts
     from the Company granted under Section 7.



(u)  "SUBSIDIARY"   means   (i)   for  purposes  of   determining
     eligibility  to  receive  a  Nonstatutory  Stock Option, any
     corporation  or  other  entity in a chain of corporations or
     other entities in which each corporation or other entity has
     a   controlling   interest  (within  the meaning of Treasury
     Regulations   section   1.409A-1(b)(5)(E)(1))  in    another
     corporation or other entity in the chain, beginning with the
     corporation  or  other  entity  in  which  the Company has a
     controlling interest; and (ii) for  all  other purposes, any
     corporation of which the Company owns at least 50 percent of
     the  combined  voting power of all classes of stock or which
     is  in  a  chain  of  corporations with the Company in which
     stock possessing at least 50% of the combined  voting  power
     of all classes of stock is owned by one or more corporations
     in the chain.

(v)  "TAXABLE YEAR" means the fiscal period used by the Company
     for reporting taxes on income under the Code.

     3.   GENERAL.

     The following types of Incentive Awards may be granted under
the  Plan: Options (Incentive Stock Options or Nonstatutory Stock
Options), Stock Appreciation Rights or Restricted Stock.

     4.   STOCK.

     Subject  to  Section 13 of the Plan, there shall be reserved
for issuance under the Plan an aggregate of Three Hundred Million
(300,000,000) shares of Common Stock, which shall be  authorized,
but  unissued, shares.  Shares allocable to Incentive  Awards  or
portions  thereof  granted  under  the  Plan  that  expire,   are
forfeited,  or  otherwise  terminate  unexercised  may  again  be
subjected  to  an Incentive Award under the Plan.  The  Board  is
expressly authorized to grant an Incentive Award to a Participant
conditioned  upon  the  surrender for cancellation  of  Incentive
Awards  previously  granted to such Participant.   No  more  than
Thirty  Million  (30,000,000)  shares  of  Common  Stock  may  be
allocated  to the Options or Stock Appreciation Rights  that  are
granted  to any individual Participant who is an employee  during
any  single Taxable Year.  For purposes of determining the number
of shares that are available for Incentive Awards under the Plan,
such number shall include the number of shares under an Incentive
Award surrendered by a Participant or retained by the Company  in
payment  of  Applicable Withholding Taxes.   All  the  shares  of
Common  Stock that may be issued under the Plan may be issued  as
Incentive Stock Options.

     5.   ELIGIBILITY.

(a)  All  present  and future employees of the Company  whom  the
     Board  determines to have contributed or who can be expected
     to contribute significantly to the Company shall be eligible
     to receive Incentive Awards under the Plan.  The Board shall
     have  the  power  and  complete  discretion,  as provided in
     Section   14,   to  select  eligible  employees  to  receive
     Incentive  Awards,  and  to  determine for each employee the
     terms  and  conditions,  the  nature  of  the award, and the
     number of shares to be allocated to each employee as part of
     each Incentive Award.

(b)  The grant of an Incentive Award shall not obligate the Board
     to pay an employee any particular amount of remuneration, to
     continue  the  employment of the employee after the grant or
     to  make  further  grants  to  the  employee  at  any   time
     thereafter.



     6.   OPTIONS.

(a)  The  Board  may make grants of Options to eligible employees
     hereunder.  Whenever the Board deems it appropriate to grant
     Options,  written  notice  shall be given to the Participant
     stating  the number of shares for which Options are granted,
     the  Option  price  per  share,  whether  the  Options   are
     Incentive Stock Options  or  Nonstatutory Stock Options, the
     extent  to  which  Stock Appreciation Rights are granted (as
     provided  in  Section  7),  and  the conditions to which the
     grant and exercise of the Options are  subject. This notice,
     when  duly  accepted  in  writing  by the Participant, shall
     become a stock option agreement.  The Board  may delegate to
     the  Executive  Committee  of  the  Company's  officers  the
     authority  to  select eligible employees to receive Options,
     to  determine  the  time  or  times at which Options will be
     awarded to eligible employees and to determine the terms and
     conditions of such Options, except to the extent that such a
     delegation  would  prevent  compliance with Rule 16b-3, Code
     section  162(m) or any  other  section of the Code, or other
     applicable law or regulation. Actions taken by the Executive
     Committee  of  the  Company's  officers  pursuant  to such a
     delegation of authority shall be  subject to ratification by
     the Board.  In the event that the Executive Committee ceases
     to exist, the delegation described  above may be made to the
     President of the Company.

(b)  The  exercise  price of shares of Common Stock covered by an
     Option  shall be not less than 100% of the Fair Market Value
     of  such  Common Stock on the Date of Grant (or 110% of Fair
     Market  Value  in  the case of a grant of an Incentive Stock
     Option to a 10% shareholder (as that term is defined in Code
     section 422)).

(c)  Options  may  be exercised in whole or in part at such times
     as  may be specified by the Board in the Participant's stock
     option agreement; provided that, the exercise provisions for
     Incentive  Stock  Options  shall  in  all events not be more
     liberal than the following provisions:

          (i)  No  Incentive  Stock Option may be exercised after
     the  first  to occur of (x) ten years from the Date of Grant
     (or five years from the Date of Grant in the case of a grant
     of  an  Incentive Stock Option to a 10% shareholder (as that
     term  is  defined  in  Code  section  422), (y) three months
     following  the  date  of  the  Participant's  retirement  or
     termination  of  employment  with  the  Company  and all its
     Subsidiaries for reasons other than  Disability or death, or
     (z) one  year  following  the  date  of  the   Participant's
     termination of employment on account of Disability  or death
     (or,  if  the  Participant  dies  following  termination  of
     employment  during  the time when the Incentive Stock Option
     is otherwise exercisable, one year from the date of death).

         (ii)  An  Incentive  Stock Option by its terms, shall be
     exercisable in any calendar year only to the extent that the
     aggregate  Fair  Market  Value  (determined  at  the Date of
     Grant) of the Common Stock  with  respect to which Incentive
     Stock Options are  exercisable for the first time during the
     calendar  year  does  not  exceed  $100,000 (the "Limitation
     Amount"). Incentive Stock Options granted under the Plan and
     all  other  plans  of  the  Company  shall be aggregated for
     purposes of determining whether the  Limitation  Amount  has
     been  exceeded.   The Board may impose such conditions as it



     deems  appropriate  on  an  Incentive Stock Option to ensure
     that the foregoing requirement is  met.   If Incentive Stock
     Options  that  first  become  exercisable in a calendar year
     exceed  the  Limitation  Amount,  the excess Options will be
     treated  as  Nonstatutory  Stock  Options  to   the   extent
     permitted by law.

(d)  The  Board  may  impose  such vesting conditions  and  other
     requirements  as  the Board deems appropriate, and the Board
     may  include  such provisions regarding Change of Control as
     the Board deems appropriate.

     7.   STOCK APPRECIATION RIGHTS.

(a)  Whenever  the Board deems it appropriate, Stock Appreciation
     Rights  may  be  granted  to an eligible employee.     Stock
     Appreciation Rights may be granted in connection with all or
     any part of an Option or in a separate Incentive Award.

(b)  The  following  provisions  apply  to all Stock Appreciation
     Rights that are granted in connection with Options:

          (i)  Stock  Appreciation   Rights  shall  entitle   the
     Participant, upon  exercise  of all or any part of the Stock
     Appreciation Rights, to surrender to the Company unexercised
     that portion  of  the underlying Option relating to the same
     number of shares of  Common Stock as is covered by the Stock
     Appreciation   Rights   (or   the   portion   of  the  Stock
     Appreciation Rights so exercised) and to receive in exchange
     from  the  Company  an amount equal to the excess of (x) the
     Fair  Market  Value  on  the  date of exercise of the Common
     Stock  covered  by the surrendered portion of the underlying
     Option,  over  (y)  the  exercise  price of the Common Stock
     covered by the surrendered portion of the underlying Option.
     The Board may limit the amount that the Participant will  be
     entitled  to  receive  upon  exercise  of Stock Appreciation
     Rights.

         (ii)  Upon  the  exercise  of a Stock Appreciation Right
     and  surrender  of  the  related  portion  of the underlying
     Option,  the  Option,  to  the extent surrendered, shall not
     thereafter be exercisable.

        (iii)  Subject  to  any  further conditions upon exercise
     imposed  by  the  Board, a Stock Appreciation Right shall be
     exercisable  only  to  the extent that the related Option is
     exercisable and a  Stock  Appreciation Right shall expire no
     later than the date on which the related Option expires.

         (iv)  A  Stock  Appreciation Right may only be exercised
     at  a  time  when  the Fair Market Value of the Common Stock
     covered by the Stock Appreciation Right exceeds the exercise
     price of the Common Stock covered by the underlying Option.

(c)  The  following  provisions apply to all  Stock  Appreciation
     Rights that are not granted in connection with Options:


          (i)  Stock   Appreciation   Rights  shall  entitle  the
     Participant,   upon exercise of all or any part of the Stock
     Appreciation Rights, to receive in exchange from the Company
     an  amount  equal to the excess of (x) the Fair Market Value
     on  the  date of exercise of the Common Stock covered by the
     surrendered  Stock  Appreciation  Right,  over  (y) the Fair
     Market Value of the Common Stock on the Date of Grant of the
     Stock  Appreciation  Right.   The Board may limit the amount
     that  the  Participant  will  be  entitled  to  receive upon
     exercise of Stock Appreciation Rights.

         (ii)  A  Stock  Appreciation Right may only be exercised
     at  a  time  when  the Fair Market Value of the Common Stock
     covered  by  the  Stock  Appreciation Right exceeds the Fair
     Market Value of the Common Stock on the Date of Grant of the
     Stock Appreciation Right.

(d)  The  manner  in which the Company's obligation arising  upon
     the  exercise  of  a  Stock Appreciation Right shall be paid
     shall  be  determined by the Board and shall be set forth in
     the  Incentive  Award.   The Incentive Award may provide for
     payment in Common   Stock or cash, or a fixed combination of
     Common Stock or cash, or the  Board may reserve the right to
     determine  the  manner  of   payment  at  the time the Stock
     Appreciation Right is exercised.     Shares  of Common Stock
     issued upon the exercise of a Stock Appreciation Right shall
     be  valued  at  their  Fair  Market  Value  on  the  date of
     exercise.

(e)  Stock  Appreciation  Rights  shall be evidenced by a written
     agreement  in such form as the Board shall from time to time
     approve  and  as  shall  be consistent with the terms of the
     Plan.

     8.   METHOD OF EXERCISE OF OPTIONS AND STOCK APPRECIATION
          RIGHTS.

(a)  Options  and  Stock Appreciation Rights may be exercised  by
     the Participant giving written notice of the exercise to the
     Company,  stating  the  number of shares the Participant has
     elected  to purchase under the Option or the number of Stock
     Appreciation Rights the Participant has elected to exercise.
     In the case of  the purchase of shares under an Option, such
     notice  shall  be  effective  only  if  accompanied  by  the
     exercise price in full in  cash;  provided, however, that if
     the  terms  of an Option  so permit, the Participant may (i)
     deliver Mature Shares (valued at their Fair Market Value) in
     satisfaction  of  all  or any part of the exercise price, or
     (ii) deliver a properly executed  exercise  notice  together
     with  irrevocable  instructions  to  a  broker  to   deliver
     promptly to the Company, from the sale or loan proceeds with
     respect  to  the  sale  of Common Stock or a loan secured by
     Common Stock, the amount necessary to pay the exercise price
     and,  if  required  by  the  terms of the Option, Applicable
     Withholding Taxes.

(b)  The Company may place on any certificate representing Common
     Stock  issued  upon  the  exercise  of  an Option or a Stock
     Appreciation  Right  any  legend  deemed  desirable  by  the
     Company's counsel to comply with federal or state securities
     laws,  and  the  Company  may  require  a  customary written
     indication of the Participant's investment intent. Until the



     Participant  has  made  any  required payment, including any
     Applicable   Withholding   Taxes,  and  has  had  issued   a
     certificate for the shares of Common Stock  acquired,  he or
     she shall possess no shareholder rights with  respect to the
     shares.

(c)  Each  Participant shall agree as a condition of the exercise
     of  an  Option  or  a Stock Appreciation Right to pay to the
     Company, or  make  arrangements  satisfactory to the Company
     regarding  the  payment  to  the  Company   of,   Applicable
     Withholding  Taxes.   Until  such  amount  has  been paid or
     arrangements satisfactory to the  Company have been made, no
     stock certificate shall be issued upon  the  exercise  of an
     Option   or   cash  paid  upon  the  exercise  of  a   Stock
     Appreciation Right.

(d)  As an alternative to making a cash payment to the Company to
     satisfy  Applicable  Withholding Taxes, if the Participant's
     Option  agreement  so provides, the Participant may elect to
     (i) deliver  Mature  Shares  (valued  at  their  Fair Market
     Value)  or  (ii)  to  have the Company retain that number of
     shares  of  Common Stock (valued at their Fair Market Value)
     that  would  satisfy  all  or  a  specified  portion  of the
     Applicable Withholding Taxes.

     9. TRANSFERABILITY OF OPTIONS AND STOCK APPRECIATION RIGHTS.

Nonstatutory Stock Options and Stock Appreciation Rights  may  be
transferable  by a Participant and exercisable by a person  other
than  the  Participant,  but  only  to  the  extent  specifically
provided  in  the  Incentive  Award  agreement.  Incentive  Stock
Options, by their terms, shall not be transferable except by will
or  by  the  laws  of  descent  and  distribution  and  shall  be
exercisable,  during  the Participant's  lifetime,  only  by  the
Participant.

     10.  RESTRICTED STOCK AWARDS.

(a)  The  Board  may make grants of Restricted Stock to  eligible
     employees.  Whenever the Board deems it appropriate to grant
     Restricted  Stock,  written notice shall  be  given  to  the
     Participant stating the number of shares of Restricted Stock
     granted and the terms and conditions to which the Restricted
     Stock  is subject.  This notice, when accepted in writing by
     the Participant  shall  become a grant agreement between the
     Company and the Participant. Restricted Stock may be awarded
     by the Board in its discretion without cash consideration.

(b)  No  shares  of  Restricted  Stock  may  be  sold,  assigned,
     transferred,  pledged, hypothecated, or otherwise encumbered
     or disposed of until the restrictions on such shares as  set
     forth  in  the  Participant's grant agreement have lapsed or
     been removed pursuant to paragraph (d) or (e) below.

(c)  Upon  the  acceptance  by  a  Participant  of  an  award  of
     Restricted  Stock,  such  Participant  shall, subject to the
     restrictions  set forth in paragraph (b) above, have all the
     rights  of  a  shareholder  with  respect  to such shares of
     Restricted  Stock,  including, but not limited to, the right
     to  vote  such  shares  of Restricted Stock and the right to
     receive all dividends and other distributions  paid thereon.
     Certificates representing Restricted  Stock  shall be issued
     to the Participant but shall  bear a legend referring to the
     restrictions  set  forth  in  the Plan and the Participant's
     award agreement.



(d)  The  Board  shall  establish  as to each award of Restricted
     Stock  the  terms and conditions upon which the restrictions
     set forth in paragraph (b) above shall lapse.  The terms and
     conditions  may  include, without limitation, the lapsing of
     such  restrictions  as  a result of the Disability, death or
     retirement of the Participant or the occurrence of a  Change
     of Control.

(e)  Notwithstanding  the  provisions of paragraph (b) above, the
     Board  may  at  any time, in its sole discretion, accelerate
     the  time  at  which  any  or all restrictions will lapse or
     remove any and all such restrictions.

(f)  Each  Participant  shall  agree  at  the time the Restricted
     Stock  is granted, and as a condition thereof, to pay to the
     Company,  or  make  arrangements satisfactory to the Company
     regarding  the  payment  to  the  Company  of,    Applicable
     Withholding  Taxes.    Until  such  amount  has been paid or
     arrangements   satisfactory  to the Employer have been made,
     no  stock  certificate  free  of  a  legend  reflecting  the
     restrictions  set  forth  in  paragraph  (b)  above shall be
     issued  to  such  Participant.   As an alternative to making
     a  cash  payment  to  the  Company  to  satisfy   Applicable
     Withholding Taxes, if the grant so provides, the Participant
     may elect to (i) to deliver Mature Shares (valued at   their
     Fair Market Value) or (ii) to have the Company  retain  that
     number  of  shares  of  Common  Stock  (valued at their Fair
     Market Value)  that would satisfy all or a specified portion
     of the Applicable Withholding Taxes.

     11.  EFFECTIVE DATE OF THE PLAN.

     The original effective date of the Plan was April 30,  2001.
The  effective date of the Plan (as amended and restated  herein)
is  September  12,  2008  (the "Amended  and  Restated  Effective
Date").   The  Plan  (as amended and restated  herein)  shall  be
submitted to the shareholders of the Company for approval.  Until
(i)  the  Plan (as amended and restated herein) has been approved
by  Company's  shareholders, and (ii)  the  requirements  of  any
applicable  Federal or State securities laws have  been  met,  no
Option or Stock Appreciation Right granted under the Plan  on  or
after   the  Amended  and  Restated  Effective  Date   shall   be
exercisable.

     12.  TERMINATION, MODIFICATION, CHANGE

(a)  If  not  sooner  terminated by the Board,  this  Plan  shall
     terminate  at  the  close of business on April 30, 2011.  No
     Options  or Restricted Stock shall be granted under the Plan
     after its termination.  The Board may amend or terminate the
     Plan in such  respects  as it shall deem advisable; provided
     that, if and to the  extent  required by the Code, no change
     shall be  made  that increases the total number of shares of
     Common  Stock  reserved  for  issuance pursuant to Incentive
     Awards  granted  under  the Plan (except pursuant to Section
     13), materially  modifies the requirements as to eligibility
     for participation in the Plan, or   materially increases the
     benefits  accruing  to  Participants  under the Plan, unless
     such  change  is  authorized  by  the  shareholders  of  the
     Company.  Notwithstanding the foregoing, the Board may amend
     the Plan and unilaterally amend Incentive Awards as it deems
     appropriate  to  ensure  compliance  with applicable federal
     or state  securities  laws or regulations thereunder, or any
     applicable    NASDAQ    or    securities  exchange   listing
     requirement,  and  to  cause Incentive Stock Options to meet
     the  requirements  of  the Code and  regulations thereunder.
     Except as provided in the  preceding sentence, a termination



     or amendment of the Plan shall  not,  without the consent of
     the Participant, detrimentally affect a Participant's rights
     under   an   Incentive   Award  previously  granted  to  the
     Participant.

(b)  Notwithstanding the provisions of subsection (a) above, this
     subsection  (b) will apply if the Company is involved in any
     merger  or  similar  transaction that the Company intends to
     treat  as  a  "pooling  of interest" for financial reporting
     purposes.  In such a case, the Board may amend the terms  of
     any  Incentive  Award  or of the Plan to the extent that the
     Company's independent accountants determine that such  terms
     would preclude the use of "pooling  of interest" accounting.
     The  authority  of  the  Board  to  amend  the  terms of any
     Incentive Award or of the Plan includes, without limitation,
     the  right  (i)  to  rescind  or  suspend any terms that are
     contingent on a Change in Control, such as the  acceleration
     of vesting or provisions for special payments to an optionee
     or participant; (ii) to modify Incentive  Awards  to  comply
     with prior practices of the Company as to terms of Incentive
     Awards; (iii) to provide for payment to the Participant   of
     Common  Stock or stock of the other party to the transaction
     equal  to the fair value of the Incentive Award; and (iv) to
     suspend  any provisions for payment of an Incentive Award in
     cash.  The  authority of the Board under this section may be
     exercised in the Board's sole and complete discretion.

(c)  No  modification (within the meaning of Section 424(h)(3) of
     the  Code) shall be made with respect to any Incentive Stock
     Option  without  the Participant's consent.  No modification
     (within  the  meaning of Section 1.409A-1(b)(5)(v)(B) of the
     Treasury  Regulations)  shall  be  made  with respect to any
     Nonstatutory  Option  or  Stock  Appreciation  Right if such
     modification  would  result  in  the  Option  constituting a
     deferral  of  compensation,  and  no  extension  (within the
     meaning  of  Section 1.409A-1(b)(5)(v)(C)  of  the  Treasury
     Regulations) shall be made with  respect to any Nonstatutory
     Stock  Option  if  such extension would result in the Option
     having  an  additional  deferral  feature  from  the Date of
     Grant, in each case without the Participant's consent.

     13.  CHANGE IN CAPITAL STRUCTURE.

(a)  In the event of a stock dividend, stock split or combination
     of  shares,  recapitalization or merger in which the Company
     is  the  surviving  corporation  or  other  change  in   the
     Company's capital  stock (including, but not limited to, the
     creation  or  issuance  to shareholders generally of rights,
     options  or  warrants  for  the  purchase of common stock or
     preferred  stock  of  the  Company),  the number and kind of
     shares of stock or securities of the Company to  be  subject
     to  the Plan and to Incentive  Awards then outstanding or to
     be  granted  thereunder, the  maximum  number  of  shares or
     securities  which  may  be  delivered  under  the  Plan, the
     maximum  number  of shares or securities that can be granted
     to  an individual  Participant under Section 4, the exercise
     price,  the  terms  of  Incentive  Awards and other relevant
     provisions  shall  be proportionately adjusted by the Board,
     whose determination shall  be  binding on all persons.    If
     the adjustment would produce fractional shares or fractional
     cents with respect to any unexercised Option or its exercise
     price, the Board shall decrease the number of shares covered
     by the Option so as to   eliminate the fractional shares and
     shall  increase  the  fractional cent so as to eliminate the
     fractional cent.




(b)  If  the Company is a party to a consolidation or a merger in
     which  the  Company  is  not  the  surviving  corporation, a
     transaction that results in the acquisition of substantially
     all of the Company's outstanding stock by a single person or
     entity,  or  a  sale or transfer of substantially all of the
     Company's  assets,  the  Board  may  take  such actions with
     respect to outstanding  Incentive  Awards as the Board deems
     appropriate.

(c)  Notwithstanding  anything  in  the Plan to the contrary, the
     Board  may take the foregoing actions without the consent of
     any  Participant,  and  the  Board's  determination shall be
     conclusive and binding on all persons for all purposes.

     14.  ADMINISTRATION OF THE PLAN.

(a)  Subject  to the provisions of Section 16(b) of the  Act  and
     Rule 16b-3, the Plan shall be administered by the Board. The
     Board  shall have general authority to impose any limitation
     or condition upon an Incentive Award that  the  Board  deems
     appropriate to achieve the objectives of the Incentive Award
     and  the  Plan  and,  without  limitation and in addition to
     powers set forth elsewhere in the Plan, shall have the power
     and  complete  discretion  to  determine: (i) which eligible
     employees  shall  receive Incentive Awards and the nature of
     each  Incentive  Award, (ii) whether  all  or any part of an
     Incentive  Award  shall  be  accelerated  upon  a  Change of
     Control, (iii) the number of shares   of  Common Stock to be
     covered by each Incentive Award, (iv)  whether Options shall
     be Incentive Stock Options or Nonstatutory   Stock  Options,
     (v) when, whether and to what  extent  Stock    Appreciation
     Rights shall be granted, (vi) the  time  or  times  when  an
     Incentive Award shall be granted, (vii) whether an Incentive
     Award  shall become vested over a period of time and when it
     shall  be  fully  vested, (viii)  when  Options  and   Stock
     Appreciation  Rights  may  be  exercised,   (ix)  whether  a
     Disability exists and   whether a Participant that cannot be
     located shall be treated as   having died, (x) the manner in
     which payment will be made upon  the  exercise of Options or
     Stock Appreciation Rights,  (xi)  conditions relating to the
     length of time before disposition of   Common Stock received
     upon the exercise of Options or Stock Appreciation Rights is
     permitted, (xii) whether to authorize a   Participant (A) to
     deliver  Mature  Shares  to  satisfy  Applicable Withholding
     Taxes or (B) to have the Company withhold from the shares to
     be  issued  upon the exercise of a Nonstatutory Stock Option
     or  Stock  Appreciation Right the number of shares necessary
     to  satisfy  Applicable  Withholding Taxes, (xiii) the terms
     and conditions applicable to Restricted Stock awards,  (xiv)
     the   terms  and  conditions  on  which  restrictions   upon
     Restricted Stock shall lapse, (xv) whether to accelerate the
     time  at  which  any  or  all  restrictions  with respect to
     Restricted  Stock  will  lapse  or be  removed, (xvi) notice
     provisions  relating  to the sale of Common  Stock  acquired
     under the Plan, (xvii) the extent to which information shall
     be provided to Participants about available  tax  elections,
     (xviii)  when  Incentive  Awards may be forfeited or expire,
     and (xix) any additional requirements relating  to Incentive
     Awards that the Board deems appropriate. Notwithstanding the
     foregoing,  no  "tandem  stock  options"  (where  two  stock
     options are issued together and the exercise of one   option
     affects  the  right  to  exercise  the  other option) may be
     issued in connection with Incentive Stock Options. The Board
     shall  have  the  power  to  amend  the  terms of previously
     granted  Incentive  Awards that were granted by the Board so
     long  as  the terms as amended are consistent with the terms
     of the Plan and provided that the consent of the Participant
     is  obtained  with  respect  to  any amendment that would be



     detrimental to him or her, except that such consent will not
     be  required  if   such  amendment is  for  the  purpose  of
     complying with Rule  16b-3  or  any  requirement of the Code
     applicable to the Incentive Award.

(b)  The  Board  may adopt rules and regulations for carrying out
     the  Plan  with respect to Participants.  The interpretation
     and  construction  of any provision of the Plan by the Board
     shall be  final  and  conclusive as to any Participant.  The
     Board may  consult  with  counsel, who may be counsel to the
     Company, and  shall  not  incur any liability for any action
     taken in good faith in reliance upon the advice of counsel.

(c)  A  majority  of  the members of the Board shall constitute a
     quorum,  and  all  actions  of the Board shall be taken by a
     majority of  the members present. Any action may be taken by
     a written  instrument  signed by all of the members, and any
     action so taken  shall  be fully effective as if it had been
     taken at a meeting.

(d)  Subject  to  the  provisions of Section 16(b) of the Act and
     Rule  16b-3  and  the  Maryland General Corporation Law, the
     Board   may   delegate   its   rights,   duties   and  other
     responsibilities hereunder to the Committee, in which case a
     majority of the members of the Committee shall constitute  a
     quorum, and all actions of the Committee shall be taken by a
     majority of the members present. Any action by the Committee
     may be taken by a  written  instrument  signed by all of the
     members, and any action so taken shall be fully effective as
     if it had been taken at a meeting.  The  Board  from time to
     time may appoint members  previously  appointed and may fill
     vacancies, however caused, in the Committee.   The Committee
     shall  have,  in  connection  with the administration of the
     Plan, the powers possessed by the Board, including the power
     to  delegate  to  a  subcommittee  any of the administrative
     powers  the  Committee  is  authorized to exercise, subject,
     however,  to  such  resolutions,  not  inconsistent with the
     provisions  of the Plan, as may be adopted from time to time
     by the Board.

     15.  NOTICE.

     All  notices  and other communications required or permitted
to  be  given  under  this  Plan shall be in writing and shall be
deemed to  have been duly given if delivered personally or mailed
first class, postage prepaid, as follows (a) if to the Company -
at the principal business address of the Company to the attention
of the President of the Company; and (b) if to any Participant -
at the last address of the Participant known to the sender at the
time the notice or other communication is sent.

     16.  SHAREHOLDER RIGHTS.

     No  Participant  shall  be deemed to be the holder of, or to
have any of  the  rights of a holder with respect to, any  shares
of Common Stock subject  to  an  Option  unless  and  until  such
Participant   has   exercised  the  Option  and   satisfied   all
requirements  under  the  terms of  the  Option.   A  Participant
holding shares of Restricted Stock shall be a shareholder of  the
Company  with respect to such shares for all purposes,  including
dividend  and  voting  rights,  subject  to  the  terms  of   the
Restricted Stock award.

     17.  NO EMPLOYMENT OR OTHER SERVICE RIGHTS

     Nothing in the Plan or any instrument executed or  Incentive
Award  granted  under the Plan shall confer upon any  Participant
any  right  to continue to serve the Company in the  capacity  in



effect  at  the  time the Incentive Award was  granted  or  shall
affect the right of the Company to terminate the employment of an
employee with or without notice and with or without cause.

     18.  INTERPRETATION.

     The terms of this Plan shall be governed by the laws  of the
State  of  Maryland,  without  regard  to  the  conflict  of  law
provisions  of  any jurisdiction.  The terms  of  this  Plan  are
subject to all present and future regulations and rulings of  the
Secretary  of  the  Treasury  or his  delegate  relating  to  the
qualification of Incentive Stock Options under the Code.  If  any
provision  of  the  Plan conflicts with any  such  regulation  or
ruling, then that provision of the Plan shall be void and  of  no
effect.

     19.  SECURITIES  LAW COMPLIANCE.  If at any time counsel  to
the Company shall be of the opinion that any sale or delivery  of
Common  Stock pursuant to an Incentive Award is or may be in  the
circumstances  unlawful  or result in the  imposition  of  excise
taxes  on the Company or any Subsidiary under the statutes, rules
or  regulations of any applicable jurisdiction, the Company shall
have no obligation to make such sale or delivery, or to make  any
application  or  to  effect or to maintain any  qualification  or
registration under the Federal securities laws or otherwise  with
respect  to  Common Stock, and the right to exercise  any  Option
shall  be  suspended until, in the opinion of such counsel,  such
sale  or  delivery  shall be lawful or will  not  result  in  the
imposition  of  excise taxes on the Company  or  any  Subsidiary.
Upon  termination of any period of suspension under this  Section
19,  any Option affected by such suspension which shall not  then
have  expired or terminated shall be reinstated as to all  shares
available before such suspension and as to the shares which would
otherwise  have  become  available  during  the  period  of  such
suspension,  but  no  suspension shall extend  the  term  of  any
Option.



                                                      APPENDIX II

IGENE BIOTECHNOLOGY, INC.
AUDIT COMMITTEE CHARTER

1.   PURPOSE.   The primary function of the Audit Committee  (the
     "Committee") of Igene Biotechnology, Inc. (the "Company") is
     to   monitor  management's  and  the  independent  auditor's
     participation  in  the financial reporting  process  and  to
     otherwise   review  and  evaluate  the  audit  efforts   and
     independence of the independent accountants.

2.   COMPOSITION.

     A.   The  Committee  shall be comprised  of  three  or  more
          independent  directors as determined by  the  Company's
          Board of Directors (the "Board").

     B.   Each  member of the Committee shall be, in the  opinion
          of  the  Board, financially literate, and at least  one
          member   must  have  accounting  or  related  financial
          management expertise.  No member of the Committee shall
          have   any  relationship  to  the  Company  that  might
          interfere  with  such  member's independence  from  the
          Company and its management.  In addition, the following
          restrictions  shall  apply  to  every  member  of   the
          Committee:

          (i)  No   individual  who  is  either  an  employee  or
               executive  officer of the Company or  any  of  its
               affiliates  (or an immediate family member  of  an
               employee or executive officer of the Company)  may
               serve  on  the Committee until at least three  (3)
               years  following the termination of such  person's
               employment; and

          (ii) No individual who either is a partner, controlling
               shareholder,   or   executive   officer   of    an
               organization that has a business relationship with
               the   Company   or  who  has  a  direct   business
               relationship  with the Company may  serve  on  the
               Committee  unless  the Board determines  that  the
               relationship does not interfere with the  exercise
               of  such  member's independent judgment; provided,
               however,  that  the  Board  need  not  make   such
               determination  if at least three  (3)  years  have
               elapsed    since   the   termination    of    such
               disqualifying relationship; and

          (iii) No  individual  may  serve  on the  Committee  if
               such person is employed as an executive of another
               corporation whose compensation committee  includes
               any of the executive officers of the Company.

     C.   The  members of the Committee shall be subject to  such
          further or different restrictions and requirements  for
          qualification as may be required from time to  time  by
          the  Securities and Exchange Commission and  any  stock
          exchange which lists the Company's securities.



     D.   The  members of the Committee shall be elected  by  the
          Board at the annual meeting of the Board or until their
          successors  shall be duly elected and qualified.   Term
          of  membership of the Committee is at the discretion of
          the Board, but maintenance of continuity while bringing
          a  fresh  perspective  is to be considered.   Unless  a
          Chair is elected by the full Board, the members of  the
          Committee may designate a Chair by majority vote of the
          full membership.

3.   MEETINGS.  The Committee shall meet at least twice annually,
     or more frequently as circumstances dictate.

4.   RESPONSIBILITIES    AND    DUTIES.      To    fulfill    its
     responsibilities and duties the Committee shall:

     A.   Documents/Report Review

          (i)  Review  and  update this Charter periodically,  at
               least annually, as conditions dictate.

          (ii) Cause  the  Company's independent  accountants  to
               review,  prior  to  filing, any interim  financial
               statements  of the Company to be included  in  its
               quarterly reports on Form 10-Q.

          (iii) Discuss with  management  any  significant issues
               raised   by  the  independent   accountants   with
               respect to the quality of the Company's accounting
               principles and financial reporting processes.

          (iv) Prepare  and  submit  an  audit  committee  report
               to   be set forth in the Company's proxy statement
               which sets forth whether:

               (a)  the  Committee has reviewed and discussed the
                    Company's  audited financial statements  with
                    management;

               (b)  the   Committee   has  discussed   with   its
                    independent accountants the matters  required
                    to be discussed by SAS 61; and

               (c)  the    Committee    has   received    written
                    disclosures and a letter from its independent
                    accountants  required by ISB Standard  No.  1
                    and  has  discussed with its accountants  the
                    accountants' independence; and

               (d)  the   Committee's   recommendation   to   the
                    Company's  Board  that the audited  financial
                    statements  be  included  in  the   Company's
                    annual report on Form 10-K.

          (v)  Cause   the  Company  to  disclose  in  its  proxy
               statement   whether  the  Committee  members   are
               independent,  the  standard used  in  making  such
               determination,   and  disclosure  of   information
               regarding any member of the Committee who  is  not
               independent.



     B.   Independent Accountants.

          (i)  Have  the  authority  and  responsibility with the
               Board  for  the  selection  and  evaluation of the
               Company's   independent   accountants   and    the
               selection and appointment of their successors. The
               Company's independent accountants ultimately shall
               be accountable to the Committee and the Board.

          (ii) Recommend  to  the  Board  the  selection  of  the
               independent  accountants.   The  Committee   shall
               require  the  Company's independent accountants to
               prepare and submit to the  Committee on a periodic
               basis a formal written statement   delineating all
               relationships or services between said independent
               accountants  and the Company.  The Committee shall
               review  and  discus all relationships disclosed by
               the  Company's  independent  accountants which may
               impact upon their objectivity and independence and
               shall   be   responsible   for recommending to the
               Company's  Board  any appropriate action to ensure
               the independence of such accountants.

          (iii) Review   the   performance   of  the  independent
               accountants  and approve any proposed discharge of
               the  independent  accountants  when  circumstances
               warrant.

     C.   Ethical and Legal Compliance.

          (i)  Perform any other activities consistent with  this
               Charter, the Company's Bylaws and governing law as
               the  Committee  or  the Board  deem  necessary  or
               appropriate.

          (ii) Cause  the  Company to provide  each  exchange  on
               which  any of the Company's securities are listed,
               if  any,  on  at  least an annual basis  and  with
               respect to any changes to the composition  of  the
               Committee, with written confirmation regarding:

               (a)  any   determination  made the Company's Board
                    concerning the independence of its auditors;

               (b)  the   financial  literacy  of  the  Committee
                    members;

               (c)  the   determination  that   at   least    one
                    member  of  the  Committee has accounting  or
                    related financial management expertise; and



               (d)  the  annual  review and reassessment  of  the
                    adequacy of this Charter;

          (iii) Cause   the   Company   to   disclose   in    its
               proxy   statements   whether   the  Committee  has
               adopted  and  the  Board has  approved  a  written
               charter  for  the  Committee and,  if  applicable,
               include  a  copy of such charter a an appendix  to
               the  company's proxy statement at least once every
               three years.

           The  foregoing Charter of the Audit Committee  of  the
Board  of  Directors  of Igene Biotechnology,  Inc.,  a  Maryland
corporation, was adopted by the Audit Committee on the 1st day of
February,  2001, and approved by the Board of Directors  of  said
corporation on the 1st day of February, 2001.

Igene Biotechnology, Inc.

By: /S/ MICHAEL G. KIMELMAN
      -------------------------------
        MICHAEL G. KIMELMAN
        Secretary






                                                     APPENDIX III
                          FORM OF PROXY

IGENE BIOTECHNOLOGY, INC.

2008 Annual Meeting of Stockholders - November 3, 2008

   THIS PROXY IS SOLICITED ON BEHALF OF THE BOARD OF DIRECTORS

     The undersigned stockholder of IGENE BIOTECHNOLOGY, INC.,  a
Maryland corporation, hereby appoints Stephen F. Hiu, Michael  G.
Kimelman  and Thomas L. Kempner, and each of them the proxies  of
the  undersigned with full power of substitution to vote  at  the
2008 Annual Meeting of Stockholders of the Company to be held  at
10:00  a.m.  on  November  3, 2008, and  at  any  adjournment  or
adjournments  thereof (the "Meeting"), with all the  power  which
the undersigned would have if personally present, hereby revoking
any  proxy  heretofore given. The undersigned hereby acknowledges
receipt of the proxy statement for the Meeting and instructs  the
proxies to vote as directed on the reverse side.

     THE   BOARD  OF  DIRECTORS  RECOMMENDS  A  VOTE  "FOR"   ALL
PROPOSALS.

     CONTINUED  AND  TO  BE SIGNED ON REVERSE  SIDE--SEE  REVERSE
SIDE.  THIS  PROXY, WHEN PROPERLY SIGNED, WILL BE  VOTED  IN  THE
MANNER DIRECTED. IF NO SPECIFICATION IS MADE, THIS PROXY WILL  BE
VOTED  "FOR"  ALL PROPOSALS, AND IN THE DISCRETION OF  THE  PROXY
HOLDERS  AS  TO ANY OTHER MATTERS WHICH MAY PROPERLY COME  BEFORE
THE MEETING.

                 (To Be Signed on Reverse Side)

X     Please mark your votes as in this example.

1.   Election of Directors

FOR                         WITHHOLD AUTHORITY
all nominees listed below   to vote for all nominees listed below
_______________             _______________

     Nominees:   Stephen  F. Hiu, Thomas L. Kempner,  Michael  G.
                 Kimelman, Sidney R. Knafel, Patrick F. Monahan

     (Instruction:   To  withhold  authority  to  vote  for   any
     individual nominee, write that nominee's name below)
     _______________________________________

2.   To  authorize  and approve an amendment to the  Articles  of
     Incorporation  of  the  Company  to  increase  the number of
     authorized  shares  of  common  stock  from  750,000,000  to
     3,000,000,000 shares.

                    FOR            AGAINST        ABSTAIN
                    __________     __________     __________


3.   To  authorize  and amend the Company's 2001 Stock  Incentive
     Plan  to  increase  the number of shares available under the
     Plan from 55,000,000 to 300,000,000.

                    FOR            WITHHOLD       ABSTAIN
                    __________     __________     __________



4.   To  transact such other business as may properly come before
     the meeting, or any adjournment thereof.



PLEASE   RETURN  THE  PROXY  CARD  PROMPTLY  USING  THE  ENCLOSED
ENVELOPE.

Signature: ________________________          Date: _____________

Signature: ________________________          Date: _____________
           (SIGNATURE IF HELD JOINTLY)

Note:   Please sign exactly as name appears on stock certificate.
When  shares  are held by joint tenants both should  sign.   When
signing   as   attorney,  executor,  administrator,  trustee   or
guardian,  please  give full title as such.   If  a  corporation,
please  sign  in  full  corporate  name  by  President  or  other
authorized  officer.   If a partner, please sign  in  partnership
name by authorized person.