SECURITIES AND EXCHANGE COMMISSION ---------------------------------- WASHINGTON, D.C. 20549 ___________________ FORM 8-K CURRENT REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Date of Report (Date of earliest event reported): January 28, 2000 Cistron Biotechnology, Inc. --------------------------- (Exact name of registrant as specified in charter) Delaware 0-15271 22-2487972 (State or other jurisdiction (Commission File (IRS Employer of incorporation) Number) Identification No.) 10 Bloomfield Avenue, Pine Brook, New Jersey 07058 (Address of principal executive offices) (Zip Code) Registrant's telephone number, including area code: (973) 575-1700 Not Applicable (Former name or former address, if changed since last report) 2 Item 4.	Changes in Registrant's Certifying Accountant. ---------------------------------------------- On January 28, 2000, Cistron Biotechnology, Inc. (the "Company") dismissed the firm of Deloitte & Touche, LLP ("Deloitte") as certifying accountants. In their place, the Company has engaged the firm of Wiss and Company to act as certifying accountants for the fiscal year ended June 30, 2000. The Company's Board of Directors unanimously approved the dismissal of Deloitte & Touche, LLP and the engagement of Wiss and Company. For the prior two fiscal years, the opinions of Deloitte have been unqualified with respect to uncertainty, audit scope and accounting principle. Further, during those two prior fiscal years and the interim portion of the current fiscal year, there have been no disagreements with Deloitte on any matter of accounting principle or practice, financial statement disclosure, audit scope or audit procedure which disagreements, if not resolved to the satisfaction of Deloitte, would have caused it to make reference to the subject matter of the disagreements in connection with its report. Deloitte has been provided with a copy of the foregoing statements in respect to Item 304(a) and its letter of response has been attached hereto as an exhibit. Item 7.	Financial Statements, Pro Forma Financial Information and Exhibits. ----------------------------------------------------- (c) Exhibits. The following exhibit is filed herewith: No. DESCRIPTION --- ----------- 16.1 Letter from Deloitte & Touche dated February 3, 2000. 3 SIGNATURES ---------- Pursuant to the requirements of the Securities Exchange Act of 1934, as amended, the Registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized. Cistron Biotechnology, Inc. (Registrant) By: /s/ISIDORE S. EDELMAN ------------------------- Isidore S. Edelman Chairman & CEO Dated: February 3, 2000 4 EXHIBIT INDEX ------------- Exhibit Number Description - - -------------- ----------- 16.1 Letter from Deloitte & Touche dated February 3, 2000.