Exhibit 21 THERMO INSTRUMENT SYSTEMS INC. Subsidiaries of the Registrant As of February 20, 1998, the Registrant owned the following subsidiaries: STATE OR JURISDICTION PERCENT NAME OF OF INCORPORATION OWNERSHIP Analytical Instrument Development, Inc. Pennsylvania 100 Eberline Instrument Company Limited United Kingdom 100 Eberline Instrument Corporation New Mexico 100 Epsilon Industrial Inc. Texas 100 ESM Eberline Instruments Strahlen Germany 100 - und Umweltmesstechnik GmbH Fisons Instruments Vertriebs GmbH Germany 100 Gebruder Haake GmbH Germany 100 Gas Tech Inc. California 100 Gas Tech Australia, Pty. Ltd. Australia 50* Gas Tech Partnership California 50* Gastech Instruments Canada Ltd. Canada 100 Life Sciences International Limited United Kingdom 100 Comdate Services Limited England 100 Lipshaw Limited England 100 Luckham Limited England 100 Phicom Limited England 100 Shandon Scientific Limited England 100 Southions Investments Limited England 100 Sungel Puntar Rubber Estate Limited England 100 Westions Limited England 100 Whale Scientific Limited England 100 Helmet Securities Limited England 100 Life Sciences International GmbH Germany 100 Life Sciences International Kft Hungary 100 Life Sciences International SNC France 100 Life Sciences International France 100 (France) SA Shandon SA France 100 Life Sciences International, Inc. Pennsylvania 100 LSI North America Service Inc. Delaware 100 Shandon, Inc. Pennsylvania 100 Alko Diagnostic Corporation Massachusetts 100 E-C Apparatus Corporation Florida 100 Whale Scientific, Inc. Colorado 100 Life Sciences International Holdings BV Netherlands 100 Biosystems Oy Finland 100 Life Sciences International Poland 100 (Poland) SP z O.O Angela Scientific Instruments Limited England 100 Britlowes Limited England 100 PAGE 1 THERMO INSTRUMENT SYSTEMS INC. Subsidiaries of the Registrant STATE OR JURISDICTION PERCENT NAME OF OF INCORPORATION OWNERSHIP Commendstar Limited England 100 Consumer & Video Holdings Limited England 100 Video Communications Limited England 100 Greensecure Projects Limited England 100 Labsystems Europe GA Spain 100 Labsystems Ges mbH Austria 100 LSI (US) Inc. Delaware 100 Omnigene Limited England 59 Shandon Southern Instruments Limited England 100 Shenbridge Limited England 100 Southern Instruments Holdings Limited England 100 Metrika Systems Corporation Delaware 60** Eberline Radiometrie GmbH Germany 100 Eberline Radiometrie S.A. France 100 Gamma-Metrics California 100 Gamma-Metrics International F.S.C. Inc. Guam 100 Radiometrie U.S.A., Inc. California 100 Thermo Instrument Systems Limited United Kingdom 100 National Nuclear Corporation California 100 ONIX Systems Inc. Delaware 87** Brandt Instruments, Inc. Delaware 100 CAC Inc. Delaware 100 Flow Automation Inc. Texas 100 Thermo Instrument Controls de Mexico, Mexico 100 S.A. de C.V. (1% of which shares are owned directly by ONIX Systems Inc.) VG Gas Analysis Systems Inc. Massachusetts 100 Houston Atlas Inc. Texas 100 ONIX Holdings Limited England 100 CAC Limited United Kingdom 100 Flow Automation (UK) Limited United Kingdom 100 VG Gas Analysis Limited United Kingdom 100 Peek Measurement Limited England 100 Peek Environmental Limited England 100 Sarasota Data Products Limited England 100 Sarasota Instrumentation Limited England 100 Peek Measurement, Inc. Texas 100 TN Spectrace Europe B.V. Netherlands 100 TN Technologies Inc. Texas 100 Kay-Ray/Sensall, Inc. Delaware 100 TN Technologies Canada Inc. Canada 100 Westronics Inc. Texas 100 Optek-Nicolet Holdings Inc. Wisconsin 100 PAGE 2 THERMO INSTRUMENT SYSTEMS INC. Subsidiaries of the Registrant STATE OR JURISDICTION PERCENT NAME OF OF INCORPORATION OWNERSHIP Thermo Optek Corporation Delaware 91** (additionally, 1.47% of the shares are owned directly by The Thermo Electron Companies Inc.) Spectronic Instruments, Inc. Delaware 100 SLM International Inc. Illinois 100 Thermo Jarrell Ash Corporation Massachusetts 100 ARL Applied Research Laboratories Switzerland 100 S.A. Fisons Instruments (Proprietary) South Africa 100 Limited Thermo Optek Wissenschaftliche Austria 100 Gerate GesmbH Baird Do Brazil Representacoes Ltda. Brazil 100 Beijing Baird Analytical Instrument China 100 Technology Co. Limited Cahn Instrument Corporation Wisconsin 100 Mattson Instruments Limited United Kingdom 100 Thermo Elemental Limited United Kingdom 100 Thermo Optek Limited United Kingdom 100 Unicam Limited United Kingdom 100 Unicam Export Limited United Kingdom 100 Unicam Analytical Technology Netherlands 100 Netherlands B.V. Unicam Italia SpA Italy 100 Unicam S.A. Belgium 100 Fisons Instruments Nordic AB Sweden 100 Nicolet Instrument Corporation Wisconsin 100 Nicolet Japan K.K. Japan 100 Spectra-Tech, Inc. Wisconsin 100 Spectra-Tech, Europe Limited United Kingdom 100 Nicolet Instrument GmbH Germany 100 Optek Securities Corporation Massachusetts 100 Planweld Holding Limited United Kingdom 100 Nicolet Instrument Limited United Kingdom 100 Planweld Limited United Kingdom 100 Hilger Analytical Limited United Kingdom 100 Thermo Electron Limited United Kingdom 100 Thermo Instrument Systems Japan Delaware 100 Holdings, Inc. Nippon Jarrell-Ash Company, Ltd. Japan 100 Thermo Instruments (Canada) Inc. Canada 100 Eberline Instruments (Canada) Ltd. Canada 100 Fisons Instruments Inc. Canada 100 PAGE 3 THERMO INSTRUMENT SYSTEMS INC. Subsidiaries of the Registrant STATE OR JURISDICTION PERCENT NAME OF OF INCORPORATION OWNERSHIP Unicam Analytical Inc. Canada 100 Thermo Optek France S.A. France 100 Thermo Optek Holding B.V. Netherlands 100 Baird Europe B.V. Netherlands 100 Baird France S.A.R.L. France 100 Thermo Group B.V. Netherlands 100 Thermo Optek Materials Analysis (S.E.A.) Singapore 100 Pte Limited VG Systems Limited United Kingdom 100 ThermoSpectra Corporation Delaware 77** (additionally, 6.23% of the shares are owned directly by The Thermo Electron Companies Inc.) Diametrix Detectors, Inc. Delaware 50 Gould Instrument Systems, Inc. Ohio 100 Kevex Instruments Inc. Delaware 100 Kevex X-Ray Inc. Delaware 100 Neslab Instruments Europa BV Netherlands 100 Neslab Instruments, Inc. New Hampshire 100 Neslab Instruments Limited England 100 Nicolet Instrument Technologies Inc. Wisconsin 100 NORAN Instruments Inc. Wisconsin 100 Park Scientific Instruments Corporation California 100 Park Scientific S.A. Switzerland 100 PSI Virgin Islands Incorporated U.S. Virgin 100 Islands Sierra Research and Technology, Inc. Delaware 100 ThermoSpectra B.V. Netherlands 100 Nicolet Technologies B.V. Netherlands 100 Bakker Electronics Limited United Kingdom 100 NORAN Instruments B.V. Netherlands 100 ThermoSpectra GmbH Germany 100 Gould Nicolet Messtechnik GmbH Germany 100 NORAN Instruments GmbH Germany 100 ThermoSpectra Limited United Kingdom 100 Nicolet Technologies Ltd. United Kingdom 100 Thermo Spectra S.A. France 100 Nicolet Technologies S.A.R.L. France 100 Quest-Finnigan Holdings Inc. Virginia 100 Quest-TSP Holdings Inc. Delaware 100 PAGE 4 THERMO INSTRUMENT SYSTEMS INC. Subsidiaries of the Registrant STATE OR JURISDICTION PERCENT NAME OF OF INCORPORATION OWNERSHIP ThermoQuest Corporation Delaware 88** (43.9% of which shares are owned directly by Quest-Finnigan Holdings Inc.) (additionally, .12% of the shares are owned directly by The Thermo Electron Companies Inc.) Denley Instruments Limited England 100 E-C Apparatus Limited England 100 Finnigan FT/MS Inc. Delaware 100 Finnigan Corporation Delaware 100 Finnigan Instruments, Inc. New York 100 Finnigan International Sales, Inc. California 100 Finnigan MAT China, Inc. California 100 Finnigan MAT (Delaware), Inc. Delaware 100 Finnigan MAT Instruments, Inc. Nevada 100 Finnigan MAT International Sales, California 100 Inc. Finnigan MAT (Nevada), Inc. Nevada 100 Finnigan MAT Canada, Ltd. Canada 100 Finnigan MAT GmbH Germany 100 Finnigan MAT S.R.L. Italy 100 Thermo Separation Products Italy 100 S.R.L. Masslab Limited United Kingdom 100 Thermo Instruments Australia Pty. Australia 100 Limited ThermoQuest Ltd. United Kingdom 100 Finnigan MAT Ltd. United Kingdom 100 Finnigan MAT AB Sweden 100 Thermo Separation Products Ltd. United Kingdom 100 Finnigan Properties, Inc. California 100 Forma Scientific, Inc. Delaware 100 Forma Ohio Inc. Ohio 100 International Equipment Company Delaware 100 International Equipment Company England 100 Limited Savant Instruments, Inc. New York 100 Forma Scientific Limited England 100 Hypersil Inc. Delaware 100 Hypersil Limited England 100 Life Sciences International Hong Kong 100 (Hong Kong) Limited Life Sciences International, Inc. Pennsylvania 100 PAGE 5 THERMO INSTRUMENT SYSTEMS INC. Subsidiaries of the Registrant STATE OR JURISDICTION PERCENT NAME OF OF INCORPORATION OWNERSHIP Life Sciences International England 100 (Europe) Limited Life Sciences International England 100 (UK) Limited Kenbury Limited England 100 Savant Instruments Limited England 100 ThermoQuest B.V. Netherlands 100 Thermo Separation Products B.V. Netherlands 100 Thermo Separation Products Belgium 100 B.V. B.A. ThermoQuest France S.A. France 100 Finnigan Automass S.A. France 100 Finnigan MAT S.A.R.L. France 100 Thermo Separation Products S.A. France 100 ThermoQuest Italia S.p.A. Italy 100 ThermoQuest Spain S.A. Spain 100 ThermoQuest Wissenschaftliche Austria 100 Gerate GmbH Thermo Separation Products AG Switzerland 100 Thermo Separation Products Inc. Delaware 100 ThermoQuest GmbH Germany 100 Thermo Separation Products GmbH Germany 100 ThermoQuest K.K. Japan 100 RealFlex Systems Inc. Texas 100 SID Instruments Inc. Delaware 100 FI Instruments Inc. Delaware 100 FI S.A. France 100 Fisons Instruments BV Netherlands 100 Fisons Instruments NV Belgium 100 Fisons Instruments K.K. Japan 100 HB Instruments Inc. Delaware 100 NK Instruments Inc. Delaware 100 Thermo Capillary Electrophoresis Inc. Delaware 100 Thermo Haake Ltd. United Kingdom 100 Thermo Haake (U.K.) Limited United Kingdom 100 Thermo Instrumentos Cientificos S.A. Spain 100 Spectrace Instruments Inc. California 100 PAGE 6 THERMO INSTRUMENT SYSTEMS INC. Subsidiaries of the Registrant STATE OR JURISDICTION PERCENT NAME OF OF INCORPORATION OWNERSHIP Thermo BioAnalysis Corporation Delaware 70** (4.1% of which shares are owned directly by Quest-TSP Holdings Inc. and 1.8% of which shares are owned directly by Quest-Finnigan Holdings Inc. (Additionally, 7.12% of the shares are owned directly by The Thermo Electron Companies Inc.) Denley Instruments Inc. North Carolina 100 Fastighets AB Skrubba Sweden 100 Dynatech Laboratories spol. s.r.o. Czech Republic 100 DYNEX Technologies (Asia) Inc. Delaware 100 DYNEX Technologies Inc. Virginia 100 Hybaid BV Netherlands 100 Hybaid Limited England 100 Labsystems Espana SA Spain 100 Labsystems Inc. Delaware 100 Labysystems Japan K.K. Japan 100 Labsystems OY Finland 100 Labsystems (Hong Kong) Limited Hong Kong 99 Labsystems BTD China 33 Labsystems LHD China 33 Labsystems Lenpipette Russia 95 Labsystems Pakistan (Private) Ltd Pakistan 34 Labsystems Sweden AB Sweden 100 Labsystems (UK) Limited England 100 Life Sciences International(Benelux) B.V. Netherlands 100 Thermo BioAnalysis GmbH Germany 100 DYNEX Technologies GmbH Germany 100 Thermo LabSystems Vertriebs GmbH Germany 100 Thermo BioAnalysis (Guernsey) Ltd. Channel 100 Islands Thermo BioAnalysis Holding, Limited United Kingdom 100 Affinity Sensors Limited United Kingdom 100 Dynex Technologies Limited United Kingdom 100 Thermo BioAnalysis Limited United Kingdom 100 Thermo LabSystems Limited United Kingdom 100 Thermo BioAnalysis S.A. France 100 Thermo LabSystems S.A.R.L. France 100 Thermo LabSystem (Australia) Pty Limited Australia 100 Thermo LabSystems Inc. Massachusetts 100 Thermo Environmental Instruments Inc. California 100 PAGE 7 THERMO INSTRUMENT SYSTEMS INC. Subsidiaries of the Registrant STATE OR JURISDICTION PERCENT NAME OF OF INCORPORATION OWNERSHIP Thermo Instruments do Brasil Ltda. Brazil 100 (1% of which shares are owned directly by Thermo Jarrell Ash Corporation) Van Hengel Holding B.V. Netherlands 100 ESM Eberline Instruments Strahlen Germany 100 - und Umweltmesstechnik GmbH Fisons Instruments Vertriebs GmbH Germany 100 Gebruder Haake GmbH Germany 100 Thermo Instrument Systems B.V. Netherlands 100 Euroglas B.V. Netherlands 100 Thermo Automation Services (ThAS) B.V. Netherlands 100 This Analytical B.V. Netherlands 100 This Gas Analysis B.V. Netherlands This Lab Systems B.V. Netherlands 100 This Scientific B.V. Netherlands 100 Thermo Instruments GmbH Germany 100 Thermo Jarrell Ash, S.A. Spain 100 Thermo Vision Corporation Delaware 78** (additionally, 1.27 % of the shares are owned directly by The Thermo Electron Companies Inc.) CID Technologies Inc. New York 100 Centro Vision Inc. Delaware 100 Hilger Crystals Limited United Kingdom 100 Laser Science, Inc. Delaware 100 Oriel Instruments Corporation Delaware 100 Oriel Foreign Sales Corp. U.S. Virgin 100 Islands * Joint Venture/Partnership ** As of 1/3/98 PAGE 8