EXHIBIT 10.43

NEITHER THIS WARRANT NOR THE SHARES OF COMMON STOCK ISSUABLE UPON EXERCISE 
HEREOF HAVE BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED, OR 
ANY APPLICABLE STATE SECURITIES LAWS.  NO SALE OR DISPOSITION OF THIS WARRANT 
OR OF ANY SHARES OF COMMON STOCK ISSUED PURSUANT HERETO MAY BE EFFECTED 
WITHOUT (i) AN EFFECTIVE REGISTRATION STATEMENT RELATED THERETO, OR (ii) AN 
OPINION OF COUNSEL FOR THE HOLDER, REASONABLY SATISFACTORY IN FORM AND CONTENT 
TO THE COMPANY, THAT SUCH REGISTRATION IS NOT REQUIRED. 


                   BIOJECT MEDICAL TECHNOLOGIES INC.

                 SERIES "K" WARRANT TO PURCHASE SHARES
                            OF COMMON STOCK

THIS CERTIFIES THAT, for value received, Elan International Services, Ltd., a 
Bermuda corporation, or its affiliates or assigns or any other holder of this 
Warrant, as permitted herein (each, a "Holder"), is entitled to subscribe 
for and purchase up to 1,750,000 shares as adjusted pursuant to Section 4 
hereof(as so adjusted,  the "Shares") of the fully paid and nonassessable 
common stock without par value (the "Common Stock"), of Bioject Medical 
Technologies Inc., an Oregon corporation (the "Company"), at the price of 
$2.50 per share (such price, and such other price as shall result, from time 
to time, from the adjustments specified in Section 4 below, the "Warrant 
Price"), subject to the provisions and upon the terms and conditions 
hereinafter set forth.

1. Term.  The purchase right represented by this Warrant is exercisable, in 
whole or in part, at any time, and from time to time, from and after the date 
hereof and until 5:00 p.m. New York City Time October 15, 2002.  To the extent 
not exercised at 5:00 p.m. New York City Time on October 15, 2002, this 
Warrant shall completely and automatically terminate and expire, and 
thereafter it shall be of no force or effect whatsoever. 

2. Method of Exercise; Payment; Issuance of New Warrant. (a) The purchase 
right represented by this Warrant may be exercised by the Holder(s), in whole 
or in part and from time to time, by the surrender of this Warrant (with the 
notice of exercise form attached hereto as Annex A duly executed) at the 
principal office of the Company and by the payment to the Company of an 
amount, in cash or other immediately available funds, equal to the then 
applicable Warrant Price per Share multiplied by the number of Shares then 
being purchased.

(b)  The person or persons in whose name(s) any certificate(s) representing 
shares of Common Stock shall be issuable upon exercise of this Warrant shall 
be deemed to have become the holder(s) of record of, and shall be treated for 
all purposes as the record holder(s) of, the Shares represented thereby (and 
such Shares shall be deemed to have been issued) immediately prior to the 
close of business on the date or dates upon which this Warrant is exercised.  
Upon any exercise of the rights represented by this Warrant, certificates for 
the Shares purchased shall be delivered to the Holder(s) hereof as soon as 
possible and in any event within 10 business days of receipt of such notice 
and payment, and unless this Warrant has been fully exercised or expired, a 
new Warrant representing the portion of Shares, if any, with respect to which 
this Warrant shall not then have been exercised, shall also be issued to the 
holder hereof as soon as possible and in any event within such 30-day period.

3.  Stock Fully Paid, Reservation of Shares.  All Shares that may be issued 
upon the exercise of the rights represented by this Warrant will, upon 
issuance, be duly authorized, fully paid and nonassessable, and will be free 
from all taxes, liens and charges with respect to the issue thereof.  During 
the period within which the rights represented by this Warrant may be 
exercised, the Company will at all times have authorized, and reserved for the 
purpose of the issue upon the exercise of the purchase rights evidenced by 
this Warrant, a sufficient number of shares of its Common Stock to provide for 
the exercise of the rights represented by this Warrant.

4.  Adjustment of Warrant Price and Number of Shares.  The number and kind of 
securities purchasable upon the exercise of this Warrant and the Warrant Price 
shall be subject to the adjustment from time to time upon the occurrence of 
certain events, as follows:

(a)   Reclassification, Merger, Etc.  In case of (i) any reclassification, 
reorganization, change or conversion of securities of the class issuable upon 
exercise of this Warrant (other than a change in par value, or from par value 
to no par value), or (ii) any consolidation of  the Company with or into 
another corporation (other than a merger or consolidation with another 
corporation in which the Company is the acquiring and the surviving 
corporation and which does not result in any reclassification or change of 
outstanding securities issuable upon exercise of this Warrant), or (iii) any 
sale of all or substantially all of the assets of the Company, then the 
Company, or such successor or purchasing corporation, as the case may be, 
shall duly execute and deliver to the holder of this Warrant a new Warrant or 
a supplement hereto (in form and substance reasonably satisfactory to the 
holder of this Warrant), so that the holder of this Warrant shall have the 
right to receive, at a total purchase price not to exceed that payable upon 
the exercise of the unexercised portion of this Warrant, and in lieu of the 
shares of Common Stock theretofore issuable upon the exercise of this Warrant, 
the kind and amount of shares of stock, other securities, money and property 
receivable upon such reclassification, reorganization, change, conversion, 
merger or consolidation by a holder of the number of shares of Common Stock 
then purchasable under this Warrant.  Such new Warrant shall provide for 
adjustments that shall be as nearly equivalent as may be practicable to the 
adjustments provided for in this Section 4.  The provisions of this Section 
4(a) shall similarly attach to successive reclassifications, reorganizations, 
changes, mergers, consolidations and transfers.

(b)   Subdivision or Combination of Shares.  If the Company at any time during 
which this Warrant remains outstanding and unexpired shall subdivide or 
combine its Common Stock, (i) in the case of a subdivision, the Warrant Price 
shall be proportionately decreased and the number of Shares purchasable 
hereunder shall be proportionately increased, and (ii) in the case of a 
combination, the Warrant Price shall be proportionately increased and the 
number of Shares purchasable hereunder shall be proportionately decreased.

(c)   Stock Dividends; Etc.  If the Company at any time while this Warrant is 
outstanding and unexpired shall (i) pay a dividend with respect to Common 
Stock payable in Common Stock (or rights, options or warrants in respect 
thereof (collectively, "Options")), or (ii) issue any warrants, other than 
those currently outstanding or which the Company, prior to the date hereof has 
obligated itself to issue, or Options, other than up to 3,650,000 shares of 
Common Stock pursuant to a duly authorized and constituted stock option plan, 
to officers, directors, employees or consultants to the Company, having an 
exercise price (on a per-share basis) below the fair market value of a share 
of Common Stock on the date of authorization or grant of such Options, or 
(iii) make any other distribution with respect to Common Stock (except any 
distribution specifically provided for in Sections 4(a) and (b) above), the 
price at which the holder of this Warrant shall be able to purchase Shares 
shall be adjusted by multiplying the Warrant Price in effect immediately prior 
to such date of determination of the holders of securities entitled to receive 
such distribution, by a fraction (A) the numerator of which shall be the total 
number of shares of Common Stock outstanding immediately prior to such 
dividend or distribution, and (B) the denominator of which shall be the total 
number of shares of Common Stock outstanding immediately after such dividend 
or distribution, as if all of such Options had been exercised and the Company 
received the consideration payable in respect thereof.  Upon each adjustment 
in the Warrant Price pursuant to this Section  4(c), the number of Shares of 
Common Stock purchasable hereunder shall be adjusted, to the nearest whole 
share, to the product obtained by multiplying the number of Shares purchasable 
immediately prior to such adjustment in the Warrant Price by a fraction, the 
numerator of which shall be the Warrant Price immediately prior to such 
adjustment and the denominator of which shall be the Warrant Price immediately 
thereafter.

(d)   Repurchases or Redemptions of Common Stock or Options.  If the Company 
at any time while this Warrant is outstanding and unexpired shall repurchase 
or redeem any outstanding shares of Common Stock or any Options, other than 
its shares of Series C Preferred Stock, at a price which is greater than the 
then-current Market Price (for purposes hereof, Market Price shall be defined 
as the average closing price of the Common Stock for the 10 trading days 
ending on the day that is two business days prior to the date upon which the 
Company shall purchase or redeem any outstanding shares of Common Stock), the 
Warrant Price shall thereupon be adjusted by multiplying the Warrant Price in 
effect at the time of such repurchase by a fraction (i) the numerator of which 
shall be Warrant Price in effect immediately prior to such repurchase or 
redemption and (ii) the denominator of which shall be the fair market value of 
the consideration paid for the shares of Common Stock and/or Options at the 
time of purchase.  Upon each adjustment in the Warrant Price pursuant to this 
Section 4(d), the number of Shares of Common Stock purchasable hereunder shall 
be adjusted, to the nearest whole share, to the product obtained by 
multiplying the number of Shares purchasable immediately prior to such 
adjustment in the Warrant Price by a fraction, the numerator of which shall be 
the Warrant Price immediately prior to such adjustment and the denominator of 
which shall be the Warrant Price immediately thereafter.

(e)    No Impairment.  The Company will not, by amendment of its charter or 
bylaws or through any reorganization, recapitalization, transfer of assets, 
consolidation, merger, dissolution, issue or sale of securities or any other 
voluntary action, avoid or seek to avoid the observance or performance of any 
of the terms to be observed or performed hereunder by the Company, but will at 
all times in good faith assist in the carrying out of all the provisions of 
this Section 4 and in the taking of all such action as may be necessary or 
appropriate in order to protect the rights of the holder of this Warrant 
against impairment.

(f)    Notice of Adjustments.  Whenever the Warrant Price or the number of 
Shares purchasable hereunder shall be adjusted pursuant to this Section 4, the 
Company shall prepare a certificate setting forth, in reasonable detail, the 
event requiring the adjustment, the amount of the adjustment, the method by 
which such adjustment was calculated.  Such certificate shall be signed by its 
chief financial officer and shall be delivered to the holder of this Warrant.

(g)   Fractional Shares.  No fractional shares of Common Stock will be issued 
in connection with any exercise hereunder, but in lieu of such fractional 
shares the Company shall make a cash payment therefor based on the fair market 
value of the Common Stock on the date of exercise as reasonably determined in 
good faith by the Company's Board of Directors.

(h) Registration Requirement.  This Warrant may not be exercised by or for the 
account or benefit of any person other than Elan International Services, Ltd., 
or a transferee permitted hereunder, unless (i) the exercise transaction is 
covered by an effective registration statement under the Securities Act of 
1933, as amended (the "Act") and any applicable state securities laws; or 
(ii) registration under the Act, or any applicable state securities laws is 
not required, and the Company has received an opinion of counsel to such 
effect, in form and content satisfactory to the Company.

(i) Transferrability.   This Warrant shall be non-transferrable prior to 
February 1, 1998 and thereafter shall be transferrable only to (i) affiliates 
of the Holder or (ii) five non-affiliates thereof who are accredited 
institutions (as defined under Regulation D of the Securities Exchange Act of 
1934, as amended).

5.  Compliance with Securities Act; Disposition of Warrant or Shares of Common 
Stock.(a)  The holder of this Warrant, by acceptance hereof, agrees that this 
Warrant and the Shares to be issued upon exercise hereof are being acquired 
for investment and that such holder will not offer, sell or otherwise dispose 
of this Warrant or any Shares to be issued upon exercise hereof except under 
circumstances which will not result in a violation of applicable securities 
laws.  This Warrant and all Shares issued upon exercise of this Warrant 
(unless registered under the Act) shall be stamped or imprinted with a legend 
in substantially the following form:

"THIS SECURITY HAS NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS 
AMENDED, OR ANY APPLICABLE STATE SECURITIES LAWS.  NO SALE OR DISPOSITION MAY 
BE EFFECTED WITHOUT (i) AN EFFECTIVE REGISTRATION STATEMENT UNDER SUCH ACT AND 
APPLICABLE STATE SECURITIES LAWS RELATED THERETO OR (ii) AN OPINION OF COUNSEL 
FOR THE HOLDER, IN FORM AND CONTENT SATISFACTORY TO THE COMPANY, THAT SUCH 
REGISTRATION IS NOT REQUIRED. 

(b) With respect to any offer, sale or other disposition of this Warrant or 
any Shares acquired pursuant to the exercise of this Warrant prior to 
registration of such Shares, the holder hereof and each subsequent holder of 
this Warrant agrees to give written notice to the Company prior thereto, 
describing briefly the manner thereof, together with a written opinion of such 
holder's counsel in form and content satisfactory to the Company, if requested 
by the Company, to the effect that such offer, sale or other disposition may 
be effected without registration or qualification (under the Act as then in 
effect or any federal or state law then in effect) of this Warrant or such 
Shares and indicating whether or not under the Act certificates for this 
Warrant or such Shares to be sold or otherwise disposed of require any 
restrictive legend as to applicable restrictions on transferability in order 
to ensure compliance with the Act.  Promptly upon receiving such written 
notice and satisfactory opinion, if so requested, the Company, as promptly as 
practicable, shall notify such holder that such holder may sell or otherwise 
dispose of this Warrant or such Shares, all in accordance with the terms of 
the notice delivered to the Company.  Notwithstanding the foregoing, this 
Warrant or such Shares may be offered, sold or otherwise disposed of in 
accordance with Rule 144 as promulgated under the Act ("Rule 144"), provided 
that the Company shall have been furnished with such information as the 
Company may reasonably request to provide a reasonable assurance that the 
provisions of Rule 144 have been satisfied.  Each certificate representing 
this Warrant or the Shares thus transferred (except a transfer pursuant to 
Rule 144) shall bear a legend as to the applicable restrictions on 
transferability in order to insure compliance with the Act, unless in the  
aforesaid opinion of counsel for the holder, such legend is not required in 
order to insure compliance with the Act.  The Company may issue stop transfer 
instructions to its transfer agent in connection with such restrictions.

The shares issuable upon exercise of this Warrant are entitled to the benefit 
of certain registration rights as set forth in a Registration Rights Agreement 
dated as of the date hereof between the Company and the initial Holder named 
herein.

6.  Rights as Shareholders.  No holder of this Warrant, as such, shall be 
entitled to vote or receive dividends or be deemed the holder of Shares or any 
other securities of the Company which may at any time be issuable on the 
exercise hereof for any purpose, nor shall anything contained herein be 
construed to confer upon the holder of this Warrant, as such, any right to 
vote for the election of directors or upon any matter submitted to 
shareholders at any meeting thereof, or to receive notice of meetings, or to 
receive dividends or subscription rights or otherwise until this Warrant shall 
have been exercised and the Shares purchasable upon the exercise hereof shall 
have become deliverable, as provided herein.

7.  Representations and Warranties.  The Company represents and warrants to 
the holder of this Warrant as follows:

(a)  This Warrant has been duly authorized and executed by the Company and is 
a valid and binding obligation of the Company enforceable in accordance with 
its terms;

(b)  The Shares have been duly authorized and reserved for issuance by the 
Company and, when issued in accordance with the terms hereof, will be validly 
issued, fully paid and nonassessable; and

(c)  The execution and delivery of this Warrant are not, and the issuance of 
the Shares upon exercise of this Warrant in accordance with the terms hereof 
will not be, inconsistent with the Company's charter or bylaws, as amended, or 
by-laws, and do not and will not constitute a default under, any indenture, 
mortgage, contract or other instrument of which the Company is a party or by 
which it is bound.

8.  Miscellaneous.  (a) This Warrant and any provision hereof may be changed, 
waived, discharged or terminated only by an instrument in writing signed by 
both the Company and the holders of warrants that are outstanding at the time 
to purchase a majority of the shares of Common Stock issuable upon exercise of 
this Warrant remaining on the date of the action taken.

(b)  Any notice, request or other document required or permitted to be given 
or delivered to the holder hereof or the Company shall (i) be in writing, (ii) 
be delivered personally or sent by mail or overnight courier to the intended 
recipient to each such holder at its address as shown on the books of the 
Company or to the Company at the address indicated therefor on the signature 
page of this Warrant, unless the recipient has given notice of another 
address, and (iii) be effective on receipt if delivered personally, tw 
business days after dispatch if mailed, and one business day after dispatch if 
sent by overnight courier service.

(c)   Subject to the satisfaction of all of the provisions of this Warrant, 
the holder hereof may transfer all or any portion of this Warrant at any time 
to (i) an affiliate of the Holder initially namd herein and (ii) an aggregate 
of five non-affiliated institutions or investment vehicles, who are accredited 
investors (as that term is defined under Regulation D of the Securities Act of 
1933).

(d)  The Company covenants to the holder hereof that upon receipt of evidence 
reasonably satisfactory to the Company of the loss, theft, destruction, or 
mutilation of this Warrant and, in the case of any such loss, theft or 
destruction, upon receipt of a bond or indemnity reasonably satisfactory to 
the Company, or in the case of any such mutilation upon surrender and 
cancellation of such Warrant, the Company will make and deliver a new Warrant, 
of like tenor, in lieu of the lost, stolen, destroyed or mutilated Warrant.

(e)  The descriptive headings of the several sections and paragraphs of this 
Warrant are inserted for convenience only and do not constitute a part of this 
Warrant.

(f)  This Warrant shall be construed and enforced in accordance with, and the 
rights of the parties shall be governed by, the laws of the State of New York.


[Signature page follows]

IN WITNESS WHEREOF, Bioject Medical Technologies Inc. has executed this 
Warrant as of the date set forth below.

Bioject Medical Technologies Inc.


By:/s/ James C. O'Shea
Name:  James C. O'Shea
Title: President

Dated: October 15, 1997

 
                                                                  Annex A

NOTICE OF EXERCISE


To:  Bioject Medical Technologies Inc.


1.The undersigned hereby elects to purchase ____________ shares of Common 
Stock of Bioject Medical Technologies Inc. pursuant to the terms of the 
attached Warrant, and tenders herewith full payment of the purchase price of 
such shares, in cash or other immediately available funds.

2.Please issue a certificate or certificates representing said shares in the 
name of the undersigned or in such other name or names as are specified below:


                                                              
_____________________________________(Name)
                                                              

 (Address)                                           

3.The undersigned represents that the aforesaid shares are being acquired for 
the account of the undersigned for investment and not with a view to, or for 
resale in connection with, the distribution thereof and that the undersigned 
has no present intention of distributing or reselling such shares.

Signature:__________________________

Name:_____________________________

Address:___________________________

        ___________________________

        ___________________________

Social Security or taxpayer identification number:________________________