UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 FOR THE QUARTERLY PERIOD ENDED DECEMBER 31, 1998 Commission File Number 0-15609 AGOURON PHARMACEUTICALS, INC. (Exact name of registrant as specified in its charter) CALIFORNIA 33-0061928 (State or other jurisdiction of (I.R.S. Employer Identification No.) incorporation or organization) 10350 North Torrey Pines Road, La Jolla, California 92037-1020 (Address of principal executive offices) (Zip Code) (619) 622-3000 (Registrant's telephone number, including area code) NONE (Former name, former address and former fiscal year, if changed since last report) Indicate by check mark whether the registrant (1) has filed all reports required to be filed by Section 13 or 15(d) of the Securities Exchange Act of 1934 during the preceding 12 months (or for such shorter period that the registrant was required to file such reports), and (2) has been subject to such filing requirements for the past 90 days: Yes X No ___ Indicate the number of shares outstanding of each of the issuer's classes of common stock, as of the latest practicable date: As of February 3, 1999, the registrant had approximately 31,947,000 shares of Common Stock, no par value, outstanding. AGOURON PHARMACEUTICALS, INC. INDEX PAGE NO. -------- PART I. Financial Information ITEM 1. Financial Statements Consolidated Balance Sheet - 3 December 31, 1998 and June 30, 1998 Consolidated Statement of Income - 4 Three and Six Months Ended December 31, 1998 and 1997 Consolidated Statement of Cash Flows- 5 Six Months Ended December 31, 1998 and 1997 Notes to Consolidated Financial Statements 6 ITEM 2. Management's Discussion and Analysis of Financial 10 Condition and Results of Operations PART II. Other Information ITEM 1. Legal Proceedings 14 ITEM 2. Changes in Securities 14 ITEM 3. Defaults Upon Senior Securities 14 ITEM 4. Submission of Matters to a Vote of Security Holders 15 ITEM 5. Other Information 16 ITEM 6. Exhibits and Reports on Form 8-K 16 Signature 17 2 PART I. FINANCIAL INFORMATION ITEM 1. FINANCIAL STATEMENTS AGOURON PHARMACEUTICALS, INC. CONSOLIDATED BALANCE SHEET (Dollars in thousands) December 31, June 30, 1998 1998 ------------ -------- ASSETS (unaudited) Current assets: Cash and cash equivalents $ 34,547 $ 19,098 Short-term investments 39,187 68,025 Accounts receivable, net 68,560 51,341 Inventories 104,419 103,706 Current deferred tax assets 594 564 Other current assets 2,552 5,247 -------------- ------------- Total current assets 249,859 247,981 Property and equipment, net of accumulated depreciation and amortization of $30,431and $24,321 46,557 47,212 Deferred tax assets 71,680 64,644 Purchased intangibles 3,200 3,500 -------------- ------------- $ 371,296 $ 363,337 ============== ============= LIABILITIES AND STOCKHOLDERS' EQUITY Current liabilities: Accounts payable $ 24,858 $ 44,393 Accrued liabilities 43,577 35,356 Deferred revenue and advances 17,017 23,563 Current deferred tax liabilities 2,447 1,139 Loan payable and current portion of long-term debt 7,880 15,802 -------------- ------------- Total current liabilities 95,779 120,253 -------------- ------------- Long-term liabilities: Long-term debt, less current portion 6,375 5,892 Accrued rent 864 1,023 -------------- ------------- Total long-term liabilities 7,239 6,915 -------------- ------------- Stockholders' equity: Common stock, no par value, 75,000,000 shares authorized, 31,738,847 and 31,053,380 shares issued and outstanding 366,626 348,482 Accumulated other comprehensive income (expense) (161) 384 Accumulated deficit (98,187) (112,697) -------------- ------------- Total stockholders' equity 268,278 236,169 -------------- ------------- $ 371,296 $ 363,337 ============== ============= See accompanying notes to consolidated financial statements. 3 AGOURON PHARMACEUTICALS, INC. CONSOLIDATED STATEMENT OF INCOME (Unaudited) (In thousands, except per share amounts) Three Months Ended Six Months Ended -------------------------- -------------------------- December 31, December 31, -------------------------- -------------------------- 1998 1997 1998 1997 ----------- ----------- ----------- ----------- Revenues: Product sales $ 158,193 $ 91,800 $ 292,063 $ 171,302 Contracts 5,416 12,462 11,433 22,465 Royalties and license fees 7,100 400 12,150 2,752 ----------- ----------- ----------- ---------- 170,709 104,662 315,646 196,519 ----------- ----------- ----------- ---------- Operating expenses: Cost of product sales 74,241 37,942 131,286 72,015 Research and development 39,345 30,322 76,709 57,254 Selling, general and administrative 20,701 14,045 37,843 26,591 Royalties 28,085 15,432 53,978 28,808 ----------- ----------- ----------- ---------- 162,372 97,741 299,816 184,668 ----------- ----------- ----------- ---------- Operating income 8,337 6,921 15,830 11,851 ----------- ----------- ----------- ---------- Other income (expenses): Interest and other income 851 1,488 1,887 2,769 Interest expense (223) (206) (646) (367) ----------- ----------- ----------- ---------- 628 1,282 1,241 2,402 ----------- ----------- ----------- ---------- Income before income taxes 8,965 8,203 17,071 14,253 Income tax provision 1,345 3,281 2,561 5,701 ----------- ----------- ----------- ---------- Net income $ 7,620 $ 4,922 $ 14,510 $ 8,552 =========== =========== =========== ========== Earnings per share: Basic $ .24 $ .16 $ .46 $ .28 =========== ========== =========== ========== Diluted $ .22 $ .15 $ .43 $ .26 =========== ========== =========== ========== Shares used in calculation of: Basic 31,410 30,520 31,269 30,242 Diluted 34,237 33,238 33,661 33,298 See accompanying notes to consolidated financial statements. 4 AGOURON PHARMACEUTICALS, INC. CONSOLIDATED STATEMENT OF CASH FLOWS (Unaudited) (Dollars in thousands) Six Months Ended -------------------------- December 31, -------------------------- 1998 1997 ---------- ----------- Cash flows from operating activities: Cash received from product sales, contracts, royalties and license fees $ 291,881 $ 197,268 Cash paid to suppliers, employees and service providers (302,271) (173,520) Interest received 1,859 2,819 Interest paid (646) (367) ----------- ----------- Net cash provided (used) by operating activities (9,177) 26,200 ----------- ----------- Cash flows from investing activities: Proceeds from maturities/sales of short-term investments 44,053 56,824 Purchases of short-term investments (15,760) (105,707) Purchases of property and equipment (6,053) (9,313) ----------- ------------ Net cash provided (used) by investing activities 22,240 (58,196) ----------- ----------- Cash flows from financing activities: Net proceeds from issuance of common stock 9,825 9,417 Proceeds from credit line 30,000 12,600 Principal payments on credit line, long-term debt and capital leases (37,439) (12,972) ----------- ----------- Net cash provided (used) by financing activities 2,386 9,045 ----------- ----------- Net increase (decrease) in cash and cash equivalents 15,449 (22,951) Cash and cash equivalents at beginning of period 19,098 52,484 ----------- ----------- Cash and cash equivalents at end of period $ 34,547 $ 29,533 =========== =========== Reconciliation of net income to net cash provided (used) by operating activities: Net income $ 14,510 $ 8,552 Depreciation and amortization 7,008 3,968 Provision for deferred income taxes 2,561 5,701 Net (increase) decrease in accounts receivable and other current assets (14,524) (12,373) Net (increase) decrease in inventories (713) (20,119) Net increase (decrease) in accounts payable, accrued liabilities, deferred revenue and advances, and other liabilities (18,019) 40,471 ----------- ----------- Net cash provided (used) by operating activities $ (9,177) $ 26,200 =========== =========== See accompanying notes to consolidated financial statements. 5 AGOURON PHARMACEUTICALS, INC. NOTES TO CONSOLIDATED FINANCIAL STATEMENTS (December 31, 1998) NOTE 1 - THE COMPANY AND ITS SIGNIFICANT ACCOUNTING POLICIES THE COMPANY Agouron Pharmaceuticals, Inc. ("Agouron" or the "Company") was organized and incorporated in California in June 1984. Agouron is an integrated pharmaceutical company committed to the discovery, development, manufacturing and marketing of innovative therapeutic products engineered to inactivate proteins which play key roles in cancer, AIDS and other serious diseases. The Company, through its own sales and marketing organization, is currently marketing in the United States its first drug, VIRACEPT(R) (nelfinavir mesylate) for treatment of HIV infection. The Company is also conducting pivotal phase II/III clinical trials for AG3340 for treatment of lung and prostate cancer. In addition, Agouron has initiated a phase II/III pivotal clinical trial of REMUNE(TM) (AG1661), an immune-based therapeutic agent for treatment of HIV infection and AIDS being co-developed by Agouron and The Immune Response Corporation ("IRC"). Further, the Company has a number of programs in progress for discovery or development of other new drugs in the fields of cancer, viral disease and other serious diseases. The Company is also using the proprietary core drug discovery technology of Alanex Corporation ("Alanex"), a wholly-owned subsidiary of the Company, to accelerate the steps necessary to discover small-molecule drug candidates, from the initial identification of compounds that exhibit activity against selected biological targets to the progression of these compounds to drug candidates for human clinical trials. PRINCIPLES OF CONSOLIDATION The consolidated financial statements include the accounts of the Company and its wholly-owned subsidiaries. All significant intercompany accounts and transactions have been eliminated. FINANCIAL STATEMENTS AND ESTIMATES The consolidated balance sheet as of December 31, 1998 and the consolidated statements of income and cash flows for the three and six-month periods ended December 31, 1998 and 1997 have been prepared by the Company and have not been audited. Such financial statements, in the opinion of management, include all adjustments necessary for their fair presentation in conformity with generally accepted accounting principles. These financial statements should be read in conjunction with the financial statements and notes thereto included in the Company's June 30, 1998 Annual Report on Form 10-K. Certain information and footnote disclosures normally included in financial statements prepared in accordance with generally accepted accounting principles have been condensed or omitted pursuant to the Securities and Exchange Commission rules and regulations. Interim results are not necessarily indicative of results for the full year. 6 The preparation of financial statements in conformity with generally accepted accounting principles requires management to make estimates and assumptions that affect the reported amounts of assets, liabilities, revenues and expenses and related disclosures as of the date of the financial statements. Actual results could differ from such estimates. INVENTORIES The inventories consist of the following components: December 31, June 30, 1998 1998 ------------- ------------- Raw materials and work in process $ 99,100 $ 95,517 Finished goods 5,319 8,189 ------------- ------------- $ 104,419 $ 103,706 ============= ============= PRODUCT SALES The Company has the exclusive right to market its anti-HIV drug VIRACEPT in the United States and Canada. Accordingly, the Company ships VIRACEPT to wholesalers throughout the United States and certain provinces of Canada, and recognizes sales revenue upon shipment. Sales are reported net of discounts, rebates, chargebacks and product returns. Also included in product sales for the three and six-month periods ended December 31, 1998 are approximately $45,593,000 and $72,276,000 of sales (at cost plus contractually determined mark-ups) to F. Hoffmann-La Roche Ltd ("Roche") of clinical and commercial drug supplies to be used by Roche in its licensed territory. For the three and six-month periods ended December 31, 1997, sales to Roche were approximately $7,292,000 and $11,420,000. The Company receives a royalty on Roche's subsequent commercial sales of such drug supplies. ROYALTIES AND LICENSE FEES Royalty revenues are recognized based on estimated and actual sales of licensed products in licensed territories. For the three and six-month periods ended December 31, 1998, the Company has accrued and/or received royalties of approximately $6,800,000 and $11,725,000 resulting from estimated and actual net sales of VIRACEPT by Roche within its licensed territory. For the three and six-month periods ended December 31, 1997, Roche royalties were approximately $400,000 and $752,000. License fees are recognized as revenue when earned as generally evidenced by certain factors including: receipt of such fees, satisfaction of any performance obligations and the non-refundable nature of such fees. In August 1998, the Company and JT granted Roche certain exclusive rights to VIRACEPT in Mexico. For such rights, the Company realized as revenue a license fee of $125,000 from Roche. In December 1998, the Company granted to Zarix 7 Limited, a biopharmaceutical development company, certain exclusive rights to THYMITAQ, an anti-cancer drug. For such rights, the Company realized as revenue a license fee of $300,000. INCOME TAX PROVISION The Company records a provision for current and deferred income taxes using the liability method. EARNINGS PER SHARE Basic earnings per share is based upon the weighted average number of common shares outstanding during a period. Diluted earnings per share is based upon the weighted average number of common shares outstanding and dilutive common stock equivalents during a period. Common stock equivalents are options under the Company's stock option plans which are included in the earnings per share computation under the treasury stock method and common shares expected to be issued under the Company's employee stock purchase plan. Common stock equivalents of approximately 2,827,000 and 2,392,000 shares for the three and six-month periods ended December 31, 1998 were used to calculate diluted earnings per share. For the three and six-month periods ended December 31, 1997, common stock equivalents of approximately 2,718,000 and 3,056,000 shares were used to calculate diluted earnings per share. There are no reconciling items in calculating the numerator for basic and diluted earnings per share for any of the periods presented. CERTAIN CONCENTRATIONS A portion of the Company's research and development expenditures are related to programs funded in part by corporate partners. The termination of such collaborative research and development programs could result in the absence of any prospective funding for such programs and the need to evaluate the level of future program spending, if any. NOTE 2 - COMPREHENSIVE INCOME As of July 1, 1998, the Company adopted Statement of Financial Accounting Standards No. 130 ("FAS 130"), "Reporting Comprehensive Income," which establishes new rules for the reporting and display of comprehensive income and its components. FAS 130 requires unrealized gains and losses on the Company's available-for-sale securities to be included in other comprehensive income. The Company presents such information in its statement of stockholders' equity on an annual basis and in a footnote in its quarterly reports. During the three and six-month periods ended December 31, 1998, total comprehensive income was $7,227,000 and $13,965,000, respectively. During the three and six-month periods ended December 31, 1997, total comprehensive income was $4,922,000 and $8,552,000. 8 NOTE 3 - SUBSEQUENT EVENT On January 26, 1999, the Company announced that it had signed a definitive agreement to merge with Warner-Lambert Company, a worldwide company devoted to discovering, developing, manufacturing, and marketing quality pharmaceuticals, consumer healthcare, and confectionary products. Warner-Lambert employs more than 40,000 people worldwide. The proposed merger, which is subject to approval by Agouron's shareholders and federal regulators, will be treated as a "pooling of interests" for accounting purposes. If approved, each share of Agouron common stock will be converted into the right to receive that number of shares of Warner-Lambert common stock equal to $60.00 divided by an average closing sales price of Warner-Lambert common stock prior to the effective date of the merger, except that such ratio will not be less than .8108 or more than .9300. 9 ITEM 2. MANAGEMENT'S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS When used in this discussion, the words "believes," "anticipates" and similar expressions are intended to identify forward-looking statements. Such statements are subject to certain risks and uncertainties (including those associated with continued growth of VIRACEPT sales, the impact of competitive products and regulatory approvals) which could cause actual results to differ materially from those projected. See "Important Factors Regarding Forward-Looking Statements" attached as Exhibit 99 to the Company's Annual Report on Form 10-K for the year ended June 30, 1998 and incorporated herein by reference. Readers are cautioned not to place undue reliance on these forward-looking statements which speak only as of the date hereof. The Company undertakes no obligation to publicly release the result of any revisions to these forward-looking statements which may be made to reflect events or circumstances after the date hereof or to reflect the occurrence of unanticipated events. OVERVIEW The Company is committed to the discovery, development, manufacturing and marketing of human pharmaceuticals targeting cancer, AIDS, and other serious diseases. Operations to date have been principally funded from the Company's equity-derived working capital, various collaborative arrangements and, most recently, from the gross margin contribution of VIRACEPT. The net income reported in the three and six-month periods ended December 31, 1998 and 1997 is principally due to the commercialization of VIRACEPT while the Company's prior net operating losses reflect primarily the result of its independent research and substantial investment in the clinical and commercial development of VIRACEPT and certain anti-cancer compounds. In March 1997, VIRACEPT was approved for marketing in the United States. In January 1998, March 1998 and August 1998, VIRACEPT was approved for marketing in Europe, Japan and Canada, respectively. For the three and six-month periods ended December 31, 1998, due principally to the increasing product contribution from VIRACEPT sales, license fees and royalties, the Company realized a net income of $7,620,000 and $14,510,000. RESULTS OF OPERATIONS PRODUCT SALES Product sales for the three and six-month periods ended December 31, 1998 were approximately $158,193,000 and $292,063,000, which included sales in North America of $112,600,000 and $219,787,000, respectively. The Company anticipates that VIRACEPT sales in North America will meet or exceed $440,000,000 in fiscal 1999. 10 CONTRACT REVENUES Collaborative research and development agreements with Japan Tobacco Inc. ("JT"), Hoffmann-La Roche Inc. and F. Hoffmann-La Roche Ltd (collectively "HLR") accounted for substantially all of the Company's contract revenues for the three and six-month periods ended December 31, 1998 and 1997. Total contract revenues for the three and six-month periods decreased approximately 57% and 49% due principally to termination of the HLR collaboration in fiscal 1998. ROYALTIES AND LICENSE FEES Royalty revenues of approximately $6,800,000 and $11,725,000 have been recognized in the three and six-month periods ended December 31, 1998 based on estimated and actual Roche sales of VIRACEPT in its licensed territory. Royalties for the three and six-month periods increased from the prior year periods due to growth in European market share and sales volume. COST OF PRODUCT SALES The aggregate cost of product sales as a percentage of product sales was approximately 47% and 45% for the three and six-month periods ended December 31, 1998. The aggregate cost of product sales as a percentage of product sales was approximately 41% and 42% for the three and six-month periods ended December 31, 1997. Gross margins on North America commercial sales were approximately 72% and 71% for the three and six-month periods ended December 31, 1998. The Company anticipates that gross margins on North America sales will approximate 72% for fiscal 1999. RESEARCH AND DEVELOPMENT Research and development spending for the current three and six-month periods increased 30% and 34% from the prior year periods due generally to costs associated with increasing average staff levels and staff related spending, and increasing expenses associated with the clinical development of certain of the Company's anti-viral and anti-cancer compounds. In fiscal 1997, the Company acquired Alanex Corporation ("Alanex", a research company) and recorded a write-off of $57,500,000 (or 92% of the purchase price, including transaction costs), representing the values determined by management to be attributable to the in-process technology purchased. Of the amount written off, approximately 95% was attributed to and supported by a discounted cash flow analysis of three drug discovery programs which anticipated revenues beginning in 2003. Approximately 40% of the value was attributed to a compound with obesity and cardiovascular indications, 30% for compounds with depression and anxiety indications and 25% for a program to treat endometriosis and sex-hormone dependent tumors. The Company believes that the allocations and aggregate values attributable to these programs were reasonable and appropriate based on the commercial potential, beginning in 2003, of these three drug discovery programs, which remain the subject of research or development efforts at December 31, 1998. 11 SELLING, GENERAL AND ADMINISTRATIVE Selling, general and administrative costs for the current three and six-month periods increased by 47% and 42% from the prior year periods due principally to increasing sales and marketing activities and the support of VIRACEPT phase IV marketing studies. ROYALTIES The Company's obligation to share VIRACEPT profits with JT is reflected in royalty expense for the three and six-month periods ended December 31, 1998 and represents approximately 25% of North America product sales. Royalty expense in the prior year periods was approximately 20% of North America product sales. INCOME TAX PROVISION The income tax provision in the current quarter has been computed using an effective, combined federal and state rate of 15%. The cash obligation of such provision has been mostly offset by the utilization of deductions generated by the exercise of stock options and/or the utilization of deferred tax benefits (comprised mostly of net operating loss carryforwards and research tax credits). YEAR 2000 The Year 2000 issue results from computer programs and systems that were created to accept only two digit dates. Such systems may not be able to distinguish 20th century dates from 21st century dates. This could result in miscalculations and system failures that could inhibit a company's ability to engage in normal business activities. The Company has established a Year 2000 project team and is utilizing a multi-phased approach to address this issue. The phases included in the Company's plan are the awareness, assessment, remediation, testing, implementation, and contingency planning phases. The Company has completed the awareness and assessment phases and has begun to correct and replace those systems that are not Year 2000 compliant. The Company expects to complete internal remediation efforts by the end of fiscal year 1999, and to complete the validation and contingency phases by the end of calendar 1999. The Company has initiated communications with all of its significant external business partners to determine the extent to which the Company is vulnerable to their failures and to ascertain Year 2000 compliance and risk. The Company intends to monitor the progress of these significant business partners and will develop contingency plans in the event that a significant exposure is identified. While the Company is not presently aware of any such significant exposure, there can be no guarantee that the systems of the third-parties on which the Company relies will be Year 2000 compliant, or, that a failure to remediate by another company would not have a material adverse effect on the Company. 12 The Company estimates that the total cost of its Year 2000 project will not exceed $1,000,000, including costs already incurred. The anticipated cost of the project and the dates on which the Company expects to complete major milestones are based on management's best estimates using information that is currently available. Based on its current estimates, the Company does not anticipate that the costs associated with the Year 2000 project will have a material adverse effect on the Company's business, financial position, or results of operation. LIQUIDITY AND CAPITAL RESOURCES Prior to fiscal 1998, the Company has relied principally on equity financings and corporate collaborations to fund its operations and capital expenditures. Beginning in fiscal 1998, the gross margin from commercial sales of VIRACEPT contributed significantly to the Company's overall working capital requirements. Commercial sales of VIRACEPT for the three and six-month periods ended December 31, 1998 resulted in gross margins of approximately $83,952,000 and $160,777,000. At December 31, 1998, the Company had net working capital of approximately $154,080,000, an increase of $26,352,000 over June 30, 1998 levels due principally to the Company's pre-tax profit of $17,071,000 and $9,825,000 in proceeds from the issuance of common stock. Individual working capital components significantly impacted by the commercialization of VIRACEPT include trade accounts receivable (an increase of $11,639,000), inventories (an increase of $713,000), accounts payable (a decrease of $19,535,000) and accrued liabilities (an increase of $8,221,000, primarily due to accrued royalties payable to JT). It is anticipated that these working capital components and cash and short-term investments will continue to be significantly impacted by VIRACEPT sales. At December 31, 1998, the Company had cash, cash equivalents and short-term investments of approximately $73,734,000. The Company believes that its current capital resources, existing contractual commitments and anticipated VIRACEPT product sales are sufficient to maintain its current operations through fiscal 1999. This belief is based on current research and clinical development plans, anticipated working capital requirements associated with the expanding commercialization of VIRACEPT, the current regulatory environment, historical industry experience in the development of therapeutic drugs and general economic conditions. The Company believes that additional financing may be required to meet the planned operating needs after fiscal 1999 if significant and increasing positive cash flows are not generated from commercial activities. Such needs would include the expenditure of substantial funds to continue and expand research and development activities, conduct existing and planned preclinical studies and human clinical trials and to support the increasing working capital requirements of a growing commercial infrastructure including manufacturing, sales and marketing capabilities. As a result, the Company anticipates pursuing various financing alternatives such as collaborative arrangements and additional public offerings or private placements of securities. If such alternatives are not available, the Company may be required to defer or restrict certain commercial activities, delay or eliminate expenditures for certain of its potential products under development, cancel licenses from third parties or to license third parties to commercialize products or technologies that the Company would otherwise seek to develop or commercialize itself. 13 PART II. OTHER INFORMATION ITEM 1. Legal Proceedings: The Company is involved in certain legal or administrative proceedings generally incidental to its normal business activities. While the outcome of any such proceedings cannot be accurately predicted, the Company does not believe the ultimate resolution of any such existing matters should have a material adverse effect on its financial position or results of operations. On January 27, 1999, an action entitled Ruben v. Agouron Pharmaceuticals, Inc., et. al. was filed in San Diego Superior Court against the Company, members of its board of directors, and Warner-Lambert Company. The complaint, which purports to be a class action filed on behalf of the Company's shareholders, alleges that the board breached fiduciary duties in connection with the decision to enter into the Agreement and Plan of Merger among the Company, WLC Acquisition Corporation and Warner-Lambert Company, dated as of January 26, 1999. The complaint purports to seek various forms of relief, including a preliminary and permanent injunction against consummation of the transaction with Warner-Lambert Company and/or money damages. The Company believes the allegations are without merit. ITEM 2. Changes in Securities: None ITEM 3. Defaults Upon Senior Securities: None. 14 ITEM 4. Submission of Matters to a Vote of Security Holders: The Company held its Annual Meeting of Shareholders on December 16, 1998. The following actions were taken at the meeting: 1. Shareholders elected nine directors to serve until the next annual meeting. Of the 31,282,508 shares of Common Stock of the Company outstanding as of the October 19, 1998 record date for the Annual Meeting (the "Outstanding Shares"), the number of votes cast for and the number of votes withheld or voted against each nominee for director were as follows: Votes Votes Against or For Withheld Peter Johnson 27,904,017 127,489 Gary E. Friedman 27,903,517 127,989 John N. Abelson 27,901,277 130,229 Patricia M. Cloherty 27,602,377 429,129 A. E. Cohen 27,602,877 428,629 Michael E. Herman 27,607,127 424,379 Irving S. Johnson 27,605,663 425,843 Antonie T. Knoppers 27,603,209 428,297 Melvin I. Simon 27,904,147 127,359 2. A proposal (the "Divisional Stock Proposal") was approved. The proposal approved the amendment and restatement of the Company's Articles of Incorporation to (i) increase the number of shares of authorized Common Stock to 150,000,000 shares, of which 75,000,000 shares would initially be designated as Agouron Pharmaceuticals Stock and 25,000,000 shares would initially be designated as Oncology Division ("Oncoceutics") Common Stock, (ii) provide authorization to the Board to designate and issue any undesignated shares in one or more additional series of Common Stock, to determine the number of shares, rights, preferences, privileges and restrictions of any such series, and to increase or decrease the number of shares of any existing series, and (iii) convert each share of the Company's existing Common Stock into one share of Agouron Pharmaceuticals Stock and 0.5 shares of Oncoceutics Stock. 21,535,439 shares were voted in favor of the proposal, 5,530,848 shares were voted against the proposal, 138,535 shares abstained and 4,077,686 shares were not voted or were broker non-votes. 3. A proposal to amend the Company's 1996 Stock Option Plan to increase the number of shares available for issuance under such plan by 1,000,000 shares was approved. 22,165,340 shares were voted in favor of the proposal, 4,640,301 shares were voted against the proposal, 399,181 shares abstained and 826,684 shares were not voted or were broker non-votes. 15 4. A proposal to amend the Company's Employee Stock Purchase Plan to increase the number of shares available for purchase under such plan by 200,000 shares was approved. 25,820,930 shares were voted in favor of the proposal, 1,020,130 shares were voted against the proposal, 363,762 shares abstained and 826,684 shares were not voted or were broker non-votes. 5. The selection of PricewaterhouseCoopers LLP as the Company's independent accountants was ratified. 27,857,821 shares were voted in favor of the proposal, 66,419 shares were voted against the proposal, 107,266 shares abstained and 0 shares were not voted or were broker non-votes. ITEM 5. Other Information: None ITEM 6. Exhibits and Reports on Form 8-K: a. Exhibits: 4.1(1) Amended and Restated Rights Agreement dated as of November 10, 1998 between Agouron Pharmaceuticals, Inc. and ChaseMellon Shareholder Services, L.L.C. 10.1(2) Amended and Restated 1996 Stock Option Plan. 10.2(2) Amended and Restated Employee Stock Purchase Plan. 10.3(3) Amended 1998 Employee Stock Option Plan. 10.4 Agreement and Plan of Merger dated as of January 26, 1999 among Warner-Lambert Company, WLC Acquisition Corporation and Agouron Pharmaceuticals, Inc. 10.5 Stock Option Agreement dated as of January 26, 1999, by and between Agouron Pharmaceuticals, Inc. and Warner-Lambert Company. 10.6 Form of Employment Agreement dated January 26, 1999 executed with Peter Johnson, Marvin R. Brown, Gary E. Friedman, Barry D. Quart and R. Kent Snyder (named executive officers in Proxy Statement dated November 12, 1998). 27. Financial Data Schedule for the quarter ended December 31, 1998. b. Reports on Form 8-K: None. - ------------------ (1) Incorporated by reference to Form 8-K filed January 19, 1999. (2) Incorporated by reference to Form S-4 filed August 13, 1998. (3) Incorporated by reference to Form S-8 filed January 19, 1999. 16 SIGNATURE Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned thereunto duly authorized. AGOURON PHARMACEUTICALS, INC. Date: February 5, 1999 /s/ Steven S. Cowell --------------------------------------- Steven S. Cowell Corporate Vice President, Finance Chief Financial Officer Chief Accounting Officer 17