EMPLOYMENT AGREEMENT


         THIS AGREEMENT is made June 1, 1996, by and between BioTime,  Inc. (the
"Company"), and Judith Segall (the "Employee").

                              W I T N E S S E T H:

         WHEREAS,  the  Company  desires to employ  Employee,  and  Employee  is
willing  to  accept  such  employment,  all  on the  terms  and  subject  to the
conditions hereinafter set forth;

         NOW,   THEREFORE,   in   consideration  of  the  terms  and  conditions
hereinafter set forth, the parties hereto agree as follows:


         1. Employment. The Company hereby employs Employee, and Employee hereby
accepts  employment  with the  Company  on the terms and  conditions  herein set
forth.

         2. Term of Agreement. This Agreement shall commence on June 1, 1996 and
shall continue in effect until December 31, 2000 (the "Expiration Date"), unless
terminated pursuant to the express provisions of this Agreement.

         3.  Renewal.  This  Agreement  shall be  renewed  automatically  for an
additional  one (1) year  period  on  January  1,  2001 and on each  anniversary
thereof,  unless one party gives the other advance written notice of non-renewal
at least sixty (60) days prior to such date. Either party may elect not to renew
this Agreement with or without cause.

         4.  Position;  Duties.  Employee  shall be employed in the position and
shall  perform  the  duties  and  functions  set  forth on  EXHIBIT  A, and such
additional duties and functions as are normally carried out by an executive in a
comparable position with a developer of pharmaceutical or medical products,  and
as the Board of Directors or a duly authorized officer of the Company shall from
time to  time  reasonably  determine.  Employee  shall  devote  his or her  best
efforts,  skills  and  abilities,  on a  full-time  basis,  exclusively  to  the
Company's  business  pursuant to, and in accordance  with,  reasonable  business
policies and procedures, as fixed from time to time by the Board of Directors of
the Company (the "Board of Directors"). Employee covenants and agrees that he or
she will faithfully  adhere to and fulfill such policies as are established from
time to time by the Board of Directors.

         5. Compensation

                  5.1 Salary and Bonuses. During the term of this Agreement, the
Company shall pay to the Employee:

                         5.1.1 Base  Salary.  A base  annual  salary  (the "Base
Salary") in the following amounts: Eighty-Five Thousand Dollars ($85,000) during
the calendar year beginning

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January 1, 1996;  Ninety-Two Thousand Dollars ($92,000) during the calendar year
beginning  January 1, 1997;  Ninety-Nine  Thousand Dollars  ($99,000) during the
calendar  year  beginning  January 1, 1998;  One  Hundred Six  Thousand  Dollars
($106,000)  during the calendar year beginning  January 1, 1999; and One Hundred
Thirteen Thousand Dollars  ($113,000) during the calendar year beginning January
1, 2000. The Base Salary shall be payable in equal semi-monthly  installments or
in such other  installments as may be agreed upon between the parties.  The Base
Salary  may be  increased  from time to time in the  discretion  of the Board of
Directors.

                         5.1.2  Financing   Bonus.   Employee  shall  receive  a
one-time cash bonus in the amount of Twenty-Five  Thousand Dollars  ($25,000) if
the  Company  receives  at least  One  Million  Dollars  ($1,000,000)  of equity
financing from a pharmaceutical  company. Such bonus shall be paid within thirty
(30) days after the Company has  received  such  $1,000,000.  For the purpose of
this paragraph the following  provisions shall apply: (a) all payments made by a
pharmaceutical company on an installment basis, or upon the exercise of options,
warrants or other rights will be aggregated; and (b) in the event of an exchange
or conversion of any debt security or evidence of  indebtedness  for or into any
equity  security of the  Company,  the  indebtedness  so  converted or exchanged
(including  all  principal  and  accrued  interest)  shall be deemed paid to the
Company as equity financing on the date of such exchange or conversion. The term
"equity  financing" means the payment of cash to the Company for the purchase of
(a)  shares  of  capital  stock of any  class  of the  Company  (whether  or not
convertible  into another class of capital  stock of the  Company),  and (b) any
option,  warrant or other  security  (other than a debt  security or  instrument
evidencing indebtedness of the Company) entitling the holder thereof to purchase
or otherwise acquire capital stock.

                         5.1.3 Other Bonuses.  The Company may pay Employee such
bonuses, if any, as the Board of Directors may, from time to time determine.

                  5.2 Benefit  Plans.  Employee shall be eligible (to the extent
he or she qualifies) to participate in any retirement,  pension,  life,  health,
accident and disability  insurance,  stock option plan or other similar employee
benefit  plans  which may be adopted by the  Company  (or any other  member of a
consolidated group of which the Company is a part) for its executive officers or
other employees; provided, that Employee shall not be eligible to participate in
the  Company's  1992 Stock  Option  Plan (or any similar  stock  option or stock
purchase plan) so long as Employee is a member of the Stock Option Committee (or
other committee governing such stock option or stock purchase plan) appointed by
the Board of Directors.

                  5.3  Expense   Reimbursement.   The  Company  shall  reimburse
Employee for all reasonable expenses incurred by Employee in connection with the
performance of his or her employment  duties,  subject to the Company's policies
and procedures in effect from time to time,  and provided that Employee  submits
supporting vouchers.

                  5.4 Vacation;  Sick Leave.  Employee shall be entitled to four
weeks of vacation, without reduction in compensation, during each calendar year.
Such vacation shall be taken at

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such time as is  consistent  with the needs and  policies  of the  Company.  All
vacation  days shall  accrue based upon days of service.  The Company may,  from
time to time,  adopt policies  governing the disposition of unused vacation days
remaining at the end of the  Company's  fiscal year;  which  policies may govern
whether unused vacation days will be paid, lost, or carried over into subsequent
fiscal  years.  Employee  shall also be  entitled  to leave  from work,  without
reduction in  compensation,  due to illness to the extent allowed by the Company
consistent  with its policies and  procedures  and subject to the  provisions of
this Agreement governing termination due to disability, sickness or illness.

         6. Termination.  This Agreement shall terminate prior to the Expiration
Date upon the happening of any of the following events:

                  6.1 Death.  Automatically and without notice upon the death of
Employee;

                  6.2 Voluntary Termination by Employee. By Employee voluntarily
leaving  the employ of the  Company  with or without  the consent of the Company
(which Employee shall be entitled to do upon thirty (30) days written notice);

                  6.3  Disability.  Upon written notice of termination  from the
Company  to  Employee,  after  Employee  becomes  disabled,  either  totally  or
partially,  for a period of ninety (90) days during any one hundred  fifty (150)
day period,  so that he or she is prevented from performing his or her principal
duties pursuant to this Agreement;  provided,  that the Company's  obligation to
pay the  compensation due under Section 5 shall continue until this Agreement is
so terminated.

                  6.4 For Cause. Upon discharge of Employee,  on written notice,
by the Board of  Directors  on grounds  of: (i)  conviction  of a crime of moral
turpitude;  (ii) deliberate failure to carry out the reasonable  policies of the
Board  of  Directors,  as they  may  relate  to  Employee's  duties  under  this
Agreement;  (iii) chronic  alcohol or drug abuse;  (iv) fraud,  embezzlement  or
misappropriation  of Company assets; (v) disloyal,  dishonest or illegal conduct
in the course of his or her employment;  or (vi) a material default or breach of
any of the  covenants  made by Employee in this  Agreement.  The written  notice
delivered by the Board of Directors shall specify the ground for termination and
shall be supported by a statement of all relevant facts  constituting  cause for
termination.   Any  termination  under  this  Section  6.4  shall  be  deemed  a
termination for "cause".

                  6.5 Notice and  Opportunity to Cure. If the Company intends to
terminate this Agreement under clause (ii) or (vi) of Section 6.4, and if all of
Employee's acts or omissions giving rise to such determination to terminate this
Agreement  are,  in the  reasonable  determination  of the  Board of  Directors,
susceptible to substantially complete cure by Employee within a period of thirty
(30) days,  the written  notice given to Employee  pursuant to Section 6.4 shall
state that the effective date of termination  shall be thirty (30) days from the
date of such notice,  and such notice  shall be rescinded if Employee  effects a
substantially complete cure within such thirty (30) day period.

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                  6.6  Payment  of  Compensation  After  Termination  . Upon the
occurrence of any events set forth in Sections 6.1 through 6.4 hereof or Section
6.8, the Company shall be obligated to pay to Employee (or Employee's  estate in
the event of Employee's death) (i) the compensation due him or her under Section
5.1.1 up to the date of termination; (ii) any unpaid bonus previously awarded by
the Board of  Directors;  and  (iii)  compensation  for any  earned  but  unused
vacation,  which compensation shall be paid at the Base Salary rate in effect at
the time such unused vacation accrued.

                  6.7 Payment Upon  Termination by the Company Without Cause. In
the event this  Agreement is  terminated  by the Company for a reason other than
one of those set forth in Section 6.3 or Section 6.4 or Section 6.8, the Company
shall be required to continue to pay Employee,  as severance  compensation,  the
compensation  due him or her under Section 5.1.1, for the unexpired term of this
Agreement  (without regard to Section 3). Such severance  compensation  shall be
paid for a period equal to the number of weeks  remaining in the unexpired  term
of this Agreement  (without  regard to Section 3). Employee may elect to receive
the severance  compensation (or such part of the severance compensation as shall
then remain  unpaid) in a lump sum. Such election may be made by written  notice
to the Company,  and if such  election is made the lump sum shall be paid by the
Company within ten (10) days after such notice.

                  6.8 Change of  Control.  Notwithstanding  the  foregoing,  the
Company or its  successor,  or Employee may terminate  this  Agreement,  with or
without  cause,  in connection  with a Change of Control of the Company.  In the
event of such a  termination,  the  Company  shall pay  Employee  on the date of
termination a lump sum payment equal to the greater of (a) 2.99 times Employee's
"Base  Amount" and (b) the  compensation  due him or her under Section 5.1.1 for
the unexpired term of this Agreement (without regard to Section 3). Such payment
shall be in addition to any unpaid  amounts  otherwise  then due Employee  under
Section  5  of  this  Agreement.  Any  termination  of  this  Agreement,  except
termination  under  Sections 6.1 through 6.4,  within twelve months after either
(i) the  earliest  date on which the  Company  enters  into a letter of  intent,
memorandum of agreement,  or similar document leading to a Change of Control, or
(ii) the effective date of a Change of Control,  shall be deemed conclusively to
be a termination in connection  with a Change of Control.  If the Company or its
successor  causes  a  material  reduction  in  Employee's   responsibilities  or
compensation  after a Change of Control,  then Employee may at Employee's option
terminate  this  Agreement  under Section 6.2 any time within one hundred eighty
(180)  days  after  such  reduction,  and such  resignation  shall  be  deemed a
termination  by the  Company in  connection  with a Change of Control  and shall
entitle  Employee to the  benefits of this  Section  6.8.  For  purposes of this
Agreement, the following definitions shall apply.

                         6.8.1 "Change of Control" means (i) the  acquisition of
Voting  Securities of the Company by a Person or an Affiliated  Group  entitling
the  holder  thereof  to  elect a  majority  of the  directors  of the  Company;
provided,  that an increase in the amount of Voting  Securities held by a Person
or Affiliated Group who previously held sufficient  Voting Securities to elect a
majority  of the  directors  shall  not  constitute  a Change  of  Control;  and
provided, further, that an

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acquisition of Voting Securities by one or more Persons acting as an underwriter
in connection with a sale or distribution  of such Voting  Securities  shall not
constitute  a Change of Control  under this clause (i);  (ii) the sale of all or
substantially  all  of  the  assets  of  the  Company;  or  (iii)  a  merger  or
consolidation of the Company with or into another corporation or entity in which
the stockholders of the Company  immediately before such merger or consolidation
do not own, in the aggregate,  Voting Securities of the surviving corporation or
entity (or the ultimate parent of the surviving corporation or entity) entitling
them,  in the  aggregate  (and  without  regard to whether  they  constitute  an
Affiliated  Group) to elect a  majority  of the  directors  or  persons  holding
similar powers of the surviving corporation or entity (or the ultimate parent of
the surviving corporation or entity); provided,  however, that in no event shall
any  transaction  described in clauses (i), (ii) or (iii) be a Change of Control
if all of the Persons  acquiring  Voting  Securities or assets of the Company or
merging or  consolidating  with the  Company  are one or more direct or indirect
subsidiary or parent corporations of the Company.

                         6.8.2 "Voting Securities" means shares of capital stock
or other equity  securities  entitling the holder  thereof to regularly vote for
the election of directors  (or for person  performing a similar  function if the
issuer is not a  corporation),  but does not  include the power to vote upon the
happening of some condition or event which has not yet occurred.

                         6.8.3   "Person"   means  any  natural  person  or  any
corporation,  partnership,  limited  liability  company,  trust,  unincorporated
business association or other entity.

                         6.8.4 "Affiliated  Group" means (i) a Person and one or
more other Persons in control of,  controlled  by, or under common  control with
such Person;  and (ii) two or more Persons who, by written agreement among them,
act in concert to acquire Voting  Securities  entitling them to elect a majority
of the directors of the Company.

         7. Renegotiation.  Employee shall be entitled to seek a modification of
this Agreement prior to the Expiration Date if the market value of the Company's
outstanding  capital stock exceeds  $75,000,000.  The Company will  negotiate in
good faith with Employee in connection with any such request by the Employee for
such a modification of this Agreement.

         8.  Intellectual  Property  Agreement.  Employee  acknowledges that the
Intellectual  Property Agreement  previously  executed and delivered by Employee
shall remain in effect and shall not be affected by the terms of this  Agreement
or the termination of this Agreement.

         9. Entire  Agreement.  The provisions of this Agreement,  including the
exhibits  attached to this Agreement,  constitute the entire  agreement  between
Employee and the Company with respect to the subject  matter of this  Agreement,
and  supersede  any prior oral  understanding.  No  modification,  supplement or
discharge of this Agreement shall be effective unless in writing and executed on
behalf of the party to be charged.


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         10.  Waiver.  No  waiver  by  either  party of any  condition,  term or
provision of this Agreement  shall be deemed to be a waiver of any proceeding or
succeeding  breach of the same or of any other  condition,  term or provision of
this Agreement.

         11.  Assignability.  This Agreement,  and the rights and obligations of
the parties under this Agreement,  may not be assigned by Employee.  The Company
may  assign  any of its  rights and  obligations  under  this  Agreement  to any
successor or surviving corporation resulting from a merger, consolidation,  sale
of assets or stock, or other corporate  reorganization,  upon condition that the
assignee  shall  assume,  either  expressly  or by  operation of law, all of the
Company's obligations under this Agreement.

         12.   Counterparts.   This   Agreement   may  be  executed  in  several
counterparts,  each of  which  shall  be  deemed  an  original  but all of which
together shall constitute one and the same instrument.

         13. Construction.  This Agreement shall be construed in accordance with
the laws of the State of California.

         14.  Survival.  This  Section  14  and  the  covenants  and  agreements
contained in Sections  5.3, 6.6,  6.7, and 6.8 of this  Agreement  shall survive
termination of Employee's employment.

         15. Notices.  Any notices or other communication  required or permitted
to be given under this Agreement shall be in writing and shall be sent by United
States mail, first class certified or registered postage prepaid, return receipt
requested, or personally delivered to the parties at the following addresses:

         To the Company:                    BioTime, Inc.
                                            935 Pardee Street
                                            Berkeley, California 94710
                                            Attention:  President

         To Employee:                       Judith Segall
                                            935 Pardee Street
                                            Berkeley, California 94710

A notice sent by certified or registered  mail shall be deemed  delivered on the
fourth  day after  deposit in the  United  States  mail,  postage  prepaid,  and
addressed  as  aforesaid.  Any party may change its address for notice by giving
notice to the other party in the manner provided in this Section.

         16. Unenforceable  Provisions. If all or part of any one or more of the
provisions  contained  in this  Agreement  is for any reason held to be invalid,
illegal,  or  unenforceable  in any  respect,  the  invalidity,  illegality,  or
unenforceability shall not affect any other provisions, and this

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Agreement  shall be  equitably  construed  as if it did not contain the invalid,
illegal, or unenforce able provision.

         17. Section  Headings.  Section headings are for the convenience of the
parties and do not form a part of this Agreement.

         18.  Section and Other  References.  References  in this  Agreement  to
Sections,  subsections,  and Exhibits are references to sections and subsections
in this  Agreement  and exhibits  attached to this  Agreement  unless  specified
otherwise.


         IN WITNESS WHEREOF,  the parties hereto have executed this Agreement on
the day and year first above written.

                              /s/ Judith Segall
EMPLOYEE:                    ___________________________
                                  Judith Segall


COMPANY:                           BIOTIME, INC.

                              /s/ Victoria Bellport
                         By: __________________________

                             Chief Financial Officer
                         Title: _______________________

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                                    EXHIBIT A


                           DUTIES AND RESPONSIBILITIES


         The  Corporate  Secretary  shall be  responsible  for the  keeping  the
corporate  records as specified in the bylaws of the Company.  In such capacity,
she shall keep, or cause to be kept, at the  principal  executive  office of the
Company,  a book of minutes of all meetings of directors and shareholders,  with
the time and place of holding,  whether regular of special,  and if special, how
authorized,  the notice  thereof  given or the  waivers of notice,  the names of
those  present  at  directors'  meetings,   the  number  of  shares  present  or
represented at shareholders'  meetings and proceedings  thereof. She shall keep,
or cause to be kept, at the principal executive office of the Company, or at the
office of the Company's  transfer agent, a share  register,  as specified in the
Company's  bylaws.  She shall also keep,  or cause to be kept,  at the principal
executive office of the Company, the original or a copy of the bylaws as amended
or otherwise  altered to date,  certified by her. She shall give, or cause to be
given, notice of all meetings of shareholders and directors required to be given
by law or the bylaws.  She shall have charge of the seal of the Company and have
such other  powers  and  perform  such other  duties as may from time to time be
prescribed by the board or the bylaws.

         She will  also  serve  as the Vice  President  of  Technology.  In such
capacity,  and subject to the ultimate authority of the Board of Directors,  she
will be involved in the procurement,  development, management and maintenance of
Company-operated  facilities,  laboratories,  offices  and  equipment.  She will
participate  in the  acquisition  and use of new apparatus and  instrumentation,
including those areas of communications and computer  sciences.  She will attend
scientific  meetings,  present  scientific  papers and discussions and interface
with the mass and professional media. She will participate in and manage company
experimentation,  scientific services, and product manufacturing,  especially in
the areas of  clinical  and  nutritional  chemistry,  electronics  and  computer
sciences. She will work with technical and non-technical management in designing
company policy and direction.  She will participate in the design and activities
of the Company's marketing programs.

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