AMENDMENT TO EMPLOYMENT AGREEMENT THIS AGREEMENT is made as of April 1, 1999, by and between BioTime, Inc. (the "Company"), and Ronald S. Barkin (the "Employee"). W I T N E S S E T H: WHEREAS, Employee and the Company desire to amend Employee's Employment Agreement dated April 1, 1997 ("Employment Agreement"); NOW, THEREFORE, in consideration of the terms and conditions hereinafter set forth, the parties hereto agree as follows: Section 5.1.1 of the Employment Agreement is amended to provide that the Base Salary shall be One Hundred Seventeen Thousand Dollars ($117,000) during the nine months beginning April 1, 1999; and One Hundred Sixty-Three Thousand Dollars ($163,000) during the calendar year beginning January 1, 2000. IN WITNESS WHEREOF, the parties hereto have executed this Amendment to Employment Agreement as of the day and year first above written. /s/Ronald S. Barkin EMPLOYEE: _______________________________ Ronald S. Barkin COMPANY: BIOTIME, INC. /s/Paul Segall By: ___________________________ Paul Segall, Chief Executive Officer /s/Judith Segall By: ___________________________ Judith Segall, Secretary