EXHIBIT 11.1 INCYTE PHARMACUETICALS, INC. STATEMENT RE: COMPUTATION OF EARNINGS (LOSS) PER SHARE (in thousands, except per share amounts) THREE MONTHS ENDED NINE MONTHS ENDED SEPTEMBER 30, SEPTEMBER 30, ----------------- ----------------- 1997 1996 1997 1996 ------- -------- ------- -------- Primary Earnings (Loss) Per Share - ------------------------------------------ Weighted average common shares outstanding during the period. . . . . . 22,881 20,358 21,609 20,212 Adjustment for dilutive effect of outstanding stock options. . . . . . . . 1,915 - 1,915 - Weighted average common and common stock equivalent shares used for primary earnings (loss) per share. . . . 24,796 20,358 23,524 20,212 ======= ======== ======= ======== Net income (loss). . . . . . . . . . . . . $ 3,044 $(3,352) $ 5,967 $(6,987) ======= ======== ======= ======== Net income (loss) per share. . . . . . . . $ 0.12 $ (0.16) $ 0.25 $ (0.35) ======= ======== ======= ======== Fully Diluted Earnings (Loss) Per Share - ------------------------------------------ Weighted average common shares outstanding during the period. . . . . . 22,881 20,358 21,609 20,212 Adjustment for dilutive effect of outstanding stock options. . . . . . . . 2,146 - 2,057 - Weighted average common and common stock equivalent shares used for fully diluted earnings (loss) per share. 25,027 20,358 23,666 20,212 ======= ======== ======= ======== Net income (loss). . . . . . . . . . . . . $ 3,044 $(3,352) $ 5,967 $(6,987) ======= ======== ======= ======== Net income (loss) per share. . . . . . . . $ 0.12 $ (0.16) $ 0.25 $ (0.35) ======= ======== ======= ======== <FN> Note: Fully diluted earnings (loss) per share is not presented separately on the face of the Statement of Operations as the dilution of the outstanding stock options does not differ materially.