UNITED STATES
                      SECURITIES AND EXCHANGE COMMISSION
                           WASHINGTON, D. C.  20549

                                 ____________


                                   FORM 8-K



                                CURRENT REPORT



                    PURSUANT TO SECTION 13 OR 15(D) OF THE
                        SECURITIES EXCHANGE ACT OF 1934


                       DATE OF REPORT:  JANUARY 22, 1998
                       (Date of earliest event reported)


                         INCYTE PHARMACEUTICALS, INC.
            (Exact name of registrant as specified in its charter)


           DELAWARE                0-27488                    94-3136539
(State or other jurisdiction     (Commission                (IRS Employer
      of  incorporation)         File  Number)          Identification  No.)


                               3174 PORTER DRIVE
                         PALO ALTO, CALIFORNIA, 94304
                   (Address of principal executive offices)


                                (650) 855-0555
             (Registrant's telephone number, including area code)

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Item  2.          Acquisition  or  Disposition  of  Assets.
                  ----------------------------------------

     On  January 22, 1998, Bond Acquisition Corporation ("Merger Subsidiary"),
a Delaware corporation and a wholly owned subsidiary of the Registrant, Incyte
Pharmaceuticals,  Inc.  ("Incyte"),  was  merged  with  and into Synteni, Inc.
("Synteni"),  a  Delaware  corporation,  pursuant to the Agreement and Plan of
Merger,  dated  as  of December 23, 1997, among Incyte, Merger Subsidiary, and
Synteni  (the  "Agreement").    The  merger of Merger Subsidiary with and into
Synteni (the "Merger") became effective at the time of filing of a certificate
of  merger  with  the  Delaware  Secretary  of  State on January 22, 1998 (the
"Effective  Time").    At  the Effective Time, (i) Merger Subsidiary ceased to
exist,  (ii)  Synteni,  as  the  surviving corporation in the Merger, became a
wholly  owned  subsidiary  of  Incyte, and (iii) each share of Synteni capital
stock  (a "Synteni Share") outstanding immediately prior to the Effective Time
was  converted  into  the  right to receive 0.1246 of a share of Common Stock,
$.001  par  value,  of  Incyte  ("Incyte  Common  Stock").

     In  addition,  pursuant to the Agreement, each option to purchase Synteni
Shares granted under Synteni's 1996 Equity Incentive Plan (the "Synteni Plan")
outstanding  immediately  prior  to  the  Effective Time was converted into an
option  to  purchase  Incyte  Common  Stock  and  Incyte  assumed  each  such
outstanding  Synteni  stock option in accordance with the terms of the Synteni
Plan  and  the  stock option agreement by which it is evidenced.  By virtue of
the  assumption  by  Incyte  of such Synteni stock options, from and after the
Effective  Time:  (i)  each  Synteni  stock  option  assumed  by Incyte may be
exercised  solely for Incyte Common Stock; (ii) the number of shares of Incyte
Common  Stock subject to each such Synteni stock option is equal to the number
of  Synteni  Shares  subject to such Synteni stock option immediately prior to
the  Effective  Time  multiplied by 0.1246 (the exchange ratio in the Merger),
rounded down to the nearest whole number of shares of Incyte Common Stock; and
(iii) the per share exercise price for each such Synteni stock option is equal
to  the  quotient  obtained  by  dividing the exercise price per share of such
stock  option immediately prior to the Effective Time by 0.1246, rounded up to
the  nearest  whole cent.  Pursuant to the Merger Agreement, 10% of the shares
of  Incyte  Common  Stock  to  be issued to former Synteni stockholders in the
Merger  will  be  placed in escrow as security for any losses Incyte incurs or
reasonably  anticipates  incurring  by  reason  of  breaches  by  Synteni  of
covenants,  representations  or  warranties contained in the Merger Agreement.

     The  former  stockholders  of  Synteni  are  receiving  approximately 2.3
million  shares  of  Incyte  Common Stock in the Merger (which amount includes
shares  that  continue  to  be  subject  to repurchase in the event of certain
events,  such  as  termination  of  the holder's employment with Synteni).  In
addition,  approximately  0.3  million  shares  of  Incyte Common Stock may be
issued  in  connection  with  the exercise of Synteni stock options assumed by
Incyte  pursuant  to  the  Merger.

     The Merger is intended to qualify as a tax-free reorganization within the
meaning  of  Section  368(a) of the Internal Revenue Code of 1986, as amended,
and  to  be  accounted  for  as  a  pooling  of  interests.

     Incyte  has  entered  into  a  registration rights agreement, dated as of
December  23, 1997, with the former stockholders of Synteni (the "Registration
Rights  Agreement")  pursuant to which Incyte has agreed to use its reasonable
efforts  to  file, and cause to become effective on or before July 21, 1998, a
registration  statement  with  the Securities and Exchange Commission covering
the  resale of up to 45% of the shares of Incyte Common Stock issued to former
stockholders  of  Synteni  pursuant  to  the  Merger.

     Synteni  has  developed  and  commercialized  technology  for  generating
microarrays  and  related  software and services.  Synteni provides microarray
services non-exclusively to the pharmaceutical, biotechnology and agricultural
industries.

     The  foregoing  descriptions  of  the  Merger  Agreement and Registration
Rights  Agreement  are  qualified  in  their entirety to the full text of such
Agreements,  copies  of  which  are  attached hereto as exhibits and which are
incorporated  herein  by  reference.


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Item  7.            Financial  Statements  and  Exhibits.
                    ------------------------------------

     (a)          Financial  Statements  of  Business  Acquired.

          It  is  impractical  to provide the required financial statements at
the time of the filing of this Current Report on Form 8-K.  Required financial
statements will be filed on a Form 8-K/A as soon as practicable after the date
hereof,  but  not  later  than  April  7,  1998.

     (b)          Pro  Forma  Financial  Information.

          It  is  impractical  to  provide  the  required  pro forma financial
statements  at  the  time  of  the  filing of this Current Report on Form 8-K.
Required  pro forma financial statements will be filed on a Form 8-K/A as soon
as  practicable  after  the  date  hereof,  but  not later than April 7, 1998.

     (c)          Exhibits

     2.1          Agreement and Plan of Merger, dated as of December 23, 1997,
among  Incyte Pharmaceuticals, Inc., Bond Acquisition Corporation and Synteni,
Inc.

     4.1         Registration Rights Agreement, dated as of December 23, 1997,
among  Incyte  Pharmaceuticals,  Inc.  and the former stockholders of Synteni,
Inc.  listed  therein.



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     SIGNATURE


     Pursuant  to the requirements of the Securities Exchange Act of 1934, the
registrant  has  duly  caused  this  report  to be signed on its behalf by the
undersigned  hereunto  duly  authorized.


     Dated:    February  5,  1998


                                      INCYTE  PHARMACEUTICALS,  INC.



                                       By:    /s/  Denise  M.  Gilbert
                                              -------------------------------

                                       Name:  Denise  M.  Gilbert
                                              -------------------------------

                                       Title: Executive  Vice  President  and
                                              -------------------------------
                                                  Chief  Financial  Officer
                                              -------------------------------