<HTML><head><TITLE>Notice of Annual Meeting</TITLE></head><table width="500" border="0" align="center" height="470">  <tr>     <td height="469">       <p align="center"><b><font size="5">PARACELSIAN, INC </font></b></p>      <p align="center"><b><i>222
Langmuir Laboratories <br>        Cornell Technology Park <br>        Ithaca, New York 14850 <br>        Telephone: (607) 257-4224 </i></b></p>      <hr width="350" noshade>      <p align="center">NOTICE OF ANNUAL MEETING OF SHAREHOLDERS <br>        Thursday, June 15, 2000 </p>
      <hr width="350" noshade>      <p align="left">&nbsp;</p>      <p align="left">To the Shareholders:</p>      <p align="left">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Notice         is hereby given that the Annual Meeting of the
Shareholders (the "Meeting")         of Paracelsian, Inc. (the "Corporation") will be held at 10:00 a.m., local         time, on Thursday, June 15, 2000, at the Ramada Inn, 2310 North Triphammer         Road, Ithaca, New York, or at any adjournment
thereof, for the following         purposes:</p>      <p align="left"> &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;1.         &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;To elect three directors to serve three         year terms until the Annual Meeting of Shareholders in the year 2003,
and one director to serve a one year term until the Annual Meeting of         Shareholders in the year 2001, or until their successors have been elected         and qualified.</p>      <p align="left">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;2.         &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;To transact such other businesses as may         properly come before the meeting or any adjournment or adjournments thereof.</p>
      <p align="left"> &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Only         shareholders of record of the common stock of the Corporation at the close         of business on May 12, 2000 are entitled to notice of, and to vote, at         the
meeting and any adjournment or adjournments thereof. The Corporation's         stock transfer books will not be closed. At least ten days prior to the         Meeting, a complete list of the shareholders entitled to vote will be         available for
inspection by any shareholder, for any purpose germane to         the Meeting, during ordinary business hours, at the Office of the Corporation         listed above. Please fill in, date and sign the enclosed Proxy, which         is solicited by the Board
of Directors of the Corporation, and mail it         promptly in the enclosed envelope. In the event you decide to attend the         Meeting in person, you may, if you desire, revoke the Proxy and vote your         shares in person.     </td>  </tr><br><table width="500" border="0" align="center">  <tr>     <td width="213">&nbsp;</td>    <td width="277">By order of the Board of Directors,</td>  </tr>  <tr>     <td width="213">&nbsp;</td>    <td width="277">&nbsp;</td>  </tr>  <tr>
     <td width="213">&nbsp;</td>    <td width="277"><b>T. Colin Campbell</b></td>  </tr>  <tr>     <td width="213">&nbsp;</td>    <td width="277">President</td>  </tr><br><table width="500" border="0" align="center">  <tr>     <td>       <p>Dated: May
18, 2000</p>      <p align="center"><b>IMPORTANT </b></p>      <p><b>The return of your signed Proxy as promptly as possible will facilitate         arrangements for the Meeting. No postage is required if the Proxy is returned         in the enclosed envelope and
mailed in the United States. </b></p>    </td>  </tr><p>&nbsp;</p><table width="500" border="0" align="center">  <tr>     <td>       <p align="center"><b><font size="5">PARACELSIAN, INC </font></b></p>      <p align="center"><b><i>222 Langmuir Laboratories, <br>
Cornell Technology Park<br>        Ithaca, New York 14850 </i><br>        </b></p>      <p align="center"><b>Appointment of Proxy Solicited on Behalf of <br>        The Board of Directors for the Annual Meeting to Be Held June 15, 2000         </b></p>      <p align="left">
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;The         undersigned shareholder of Paracelsian, Inc. (the "Corporation"), hereby         constitutes and appoints Gary Chabot and Jenny Bore, or either of them         (the "Proxies"),
proxies with full power of substitution to act and vote         all shares of common stock of the undersigned at the Annual Meeting of         Shareholders of the Corporation to be held at 10:00 a.m., local time,         on June 15, 2000, at the Ramada
Inn, 2310 North Triphammer Road, Ithaca,         New York, or at any adjournment thereof, in the election of directors         and upon the proposals set forth herein and described in the Proxy Statement,         and in their discretion with respect to
such other matters that may properly         be brought before the meeting or any adjournment thereof, hereby revoking         any proxies heretofore given. </p>      <p align="left"> &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;This         appointment of proxy when properly executed will be voted in the manner         directed herein. The Board of Directors recommends a vote "FOR" the
election         of the director nominees specified herein. </p>      <p align="left"><b>1. &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Election of Directors:         [Instruction: To withhold authority to vote for any nominee(s), strike         a line through the nominee's name(s) in the list below.]</b></p>
<blockquote>         <p>--&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; FOR the nominees listed below (except           as marked to the contrary below). </p>        <p>-- &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;WITHHOLD authority to vote for all           the nominees listed below. </p>
</blockquote>    </td>  </tr><br><table width="450" border="0" align="center">  <tr>     <td colspan="3"><b>Class II Directors - Three Year Term Expiring in 2003</b></td>  </tr>  <tr>     <td>&nbsp;</td>    <td>&nbsp;</td>    <td>&nbsp;</td>  </tr>  <tr>     <td>
Lianping He</td>    <td>Thomas D. Livingston </td>    <td>Dr. Mac Shaibe</td>  </tr>  <tr>     <td>&nbsp;</td>    <td>&nbsp;</td>    <td>&nbsp;</td>  </tr>  <tr>     <td colspan="3"><b>Class III Director - One Year Term Expiring in 2001</b></td>  </tr>  <tr>
     <td>&nbsp;</td>    <td>&nbsp;</td>    <td>&nbsp;</td>  </tr>  <tr>     <td>Noriyoshi Inoue</td>    <td>&nbsp;</td>    <td>&nbsp;</td>  </tr><br><table width="500" border="0" align="center">  <tr>     <td><b>2.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
&nbsp; In their discretion, upon any       other business that may properly come before the meeting or any adjournment       thereof.</b></td>  </tr><p>&nbsp;</p><p align="center"><font face="CG Times, Times New Roman"><i><br>  </i></font></p><div align="center">   <table width="500" border="0" height="1051">    <tr>       <td height="1047">         <div align="center">
 <p><font size="5"><b>PARACELSIAN, INC</b></font><br>          </p>          <p><i><b>222 Langmuir Laboratories<br>            Cornell Technology Park<br>            Ithaca, New York 14850 <br>            Telephone: (607) 257-4224 </b></i></p>        </div>
        <p align="center">&nbsp;</p>        <p align="center"><b>PROXY STATEMENT </b></p>        <p align="center"><b>ANNUAL MEETING</b></p>        <p> &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;The Board           of Directors (the "Board") of
Paracelsian, Inc. (the "Corporation"),           the principal executive offices of which are located at 222 Langmuir           Laboratories, Cornell Technology Park, Ithaca, Tomkins County, New York           14850, hereby solicits your appointment of
proxy, in the form enclosed           with this statement, for use at the Annual Meeting of Shareholders to           be held at 10:00 a.m., local time, on Thursday, June 15, 2000, at the           Ramada Inn, 2310 North Triphammer Road, Ithaca, New York,
or at any           adjournment thereof, for the purposes stated in the accompanying Notice           of Annual Meeting of Shareholders. The Board has fixed the close of           business on May 12, 2000, as the record date for the determination of
    shareholders entitled to notice of and to vote at the Annual Meeting.           Included with these proxy materials is the Corporation's 1999 Annual           Report to Shareholders. </p>        <p align="center"><b>VOTING OF APPOINTMENTS OF PROXY</b></p>        <p>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Shares can be           voted at the meeting only if the shareholder is represented by proxy           or present in
person. The persons named as proxies in the enclosed appointment           of proxy, who are referred to herein as the Proxy Committee, are Gary           Chabot and Jenny Bore (the "Proxies"), whom the Board has designated           as management
Proxies. When appointments of proxy in the enclosed form           are returned, properly executed and in time for the meeting, the shares           represented thereby will be voted at the meeting in accordance with           the directions indicated
thereon. If no directions are given, the appointment           of proxy will be voted FOR the nominees for director in Proposal 1 described           herein. If, at or before the time of the Annual Meeting, any nominee           named in Proposal 1 has
become unavailable for any reason, the Proxies           will have the discretion to vote for a substitute nominee. On such other           matters as may properly come before the meeting, the Proxies will be           authorized to vote shares
represented by appointments of proxy in accordance           with their best judgement.</p>        <p align="center"><b>REVOCATION OF APPOINTMENT OF PROXY</b></p>        <p> &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;A shareholder           giving an appointment of proxy in the accompanying form may revoke the
appointment at any time prior to the actual voting by notifying the           Corporation's Secretary in writing, or by executing another appointment           of proxy bearing a later date and filing it with the Secretary (Gary           Chabot,
Secretary, 222 Langmuir Laboratories, Cornell Technology, Ithaca,           New York 14850). In addition, if a shareholder attends the meeting in           person, the shareholder may vote his or her shares without returning           the enclosed
appointment of proxy. Even if the shareholder has returned           the appointment of proxy, the shareholder may still attend the meeting           and, after notifying the Secretary of his or her preference, vote in           person. If the shareholder
votes in person, the returned appointment           of proxy will be disregarded. </p>        <p align="center"><b>EXPENSES OF SOLICITATION</b> </p>        <p>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;In addition           to solicitation by mail, the Corporation's directors, officers and regular           employees
may solicit appointments of proxy in person or by telephone.           The Corporation will bear the cost of solicitation. Brokerage houses,           nominees, custodians, and fiduciaries are requested to forward these           proxy soliciting
materials to the beneficial owners of the Corporation's           stock held of record by such persons, and the Corporation will reimburse           their reasonable expenses in this regard. The Corporation anticipates           mailing this Proxy
Statement on or about May 18, 2000. </p>        <p align="center"><b>VOTING SECURITIES</b></p>        <p> &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;At the           close of business on May 1, 2000, there were 20,838,154 shares of common           stock, par value $0.01
per share (the "Shares"), issued and outstanding           and entitled to vote at the Annual Meeting. The Corporation is authorized           to issue 35,000,000 shares of common stock and 1,000,000 shares of preferred           stock. The voting rights
of the preferred stock are to be set by the           Board at the time such stock is issued. The Board has authorized and           issued three classes of preferred stock but did not authorize any voting           rights for the issued preferred stock.
As of the voting record date,           there were approximately 5,000 shareholders of record of the Corporation's           common stock. </p>        <p align="center"><b>VOTING PROCEDURE</b></p>        <p> &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Each share           is entitled to one vote for each matter submitted for a vote and, in           the election of directors,
for each director to be elected. In the election           of directors under Proposal 1, the four nominees receiving the highest           number of votes will be elected. Any Shares not voted or proxies marked           "Withhold Authority" will not be
counted. In instances where brokers           are prohibited from exercising discretionary authority for beneficial           owners who have not returned proxies (referred to as "broker nonvotes"),           those Shares will also not be included in vote
totals and will have           no effect on the vote under Proposal 1. </p>        <p align="center"><b>QUORUM</b> </p>        <p>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;The Corporation's           Bylaws provide that the presence, in person or by proxy, of the holders           of a majority of the
Corporation's outstanding Shares, shall constitute           a quorum at the Annual Meeting, and that if there is no quorum present           at the opening of the Meeting, the Annual Meeting may be adjourned from           time to time by the vote of a
majority of the Shares voting on the motion           to adjourn. </p>        <p align="center"><b>BENEFICIAL OWNERSHIP OF SECURITIES</b></p>        <p> &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;To the           Corporation's knowledge, as of May 1, 2000, listed below are the only
shareholders of the Corporation that owned more than five percent of           the Shares. The following table sets forth certain information as to           these shareholders:       </td>    </tr>  </div><font face="CG Times, Times New Roman"><br></font> <table width="450" border="0" align="center" cellpadding=0 cellspacing="3">  <tr>     <td width="170" height="29" valign="bottom">       <div align="left">Name of Shareholder
</div>    </td>    <td width="15" height="29">&nbsp;</td>    <td width="90" height="29" valign="bottom">       <div align="center">Shares Currently <br>        Beneficially Owned </div>    </td>    <td width="15" height="29">&nbsp;</td>    <td width="95"
height="29" valign="bottom">       <div align="center">Percent of Shares <br>        Beneficially Owned(2) </div>    </td>  </tr>  <tr>     <td width="170">       <hr noshade>    </td>    <td width="15">&nbsp;</td>    <td width="90">       <hr noshade>    </td>    <td width="15">
&nbsp;</td>    <td width="95">       <hr noshade>    </td>  </tr>  <tr>     <td width="170">&nbsp;</td>    <td width="15">&nbsp;</td>    <td width="90">&nbsp;</td>    <td width="15">&nbsp;</td>    <td width="95">&nbsp;</td>  </tr>  <tr>     <td width="170">
Biosignia, Inc<br>      100 Europa Drive, Suite 599 <br>      Chapel Hill, NC 27514 <br>    </td>    <td width="15">&nbsp;</td>    <td width="90">       <div align="right">5,713,565&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;</div>    </td>    <td width="15">&nbsp;</td>
 <td width="95">       <div align="right">27.42% </div>    </td>  </tr>  <tr>     <td width="170">&nbsp;</td>    <td width="15">&nbsp;</td>    <td width="90">&nbsp;</td>    <td width="15">&nbsp;</td>    <td width="95">&nbsp;</td>  </tr>  <tr>     <td
width="170">T. Colin Campbell<br>      100 Europa Drive, Suite 599 <br>      Chapel Hill, NC 27514 </td>    <td width="15">&nbsp;</td>    <td width="90">       <div align="right">5,753,600 (1) </div>    </td>    <td width="15">&nbsp;</td>    <td width="95">
<div align="right">27.61% </div>    </td>  </tr>  <tr>     <td width="170">&nbsp;</td>    <td width="15">&nbsp;</td>    <td width="90">&nbsp;</td>    <td width="15">&nbsp;</td>    <td width="95">&nbsp;</td>  </tr>  <tr>     <td width="170">T. Nelson Campbell<br>      100
Europa Drive, Suite 599<br>      Chapel Hill, NC 27514 <br>    </td>    <td width="15">&nbsp;</td>    <td width="90">       <div align="right">6,043,897 (1)</div>    </td>    <td width="15">&nbsp;</td>    <td width="95">       <div align="right">29.00%</div>    </td>  </tr>
<font face="CG Times, Times New Roman"><br></font> <table width="500" border="0" align="center">  <tr>     <td>       <p align="left">(1)&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Dr. Campbell and Mr. Campbell         are the principal shareholders of BioSignia, Inc.
and their total &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;shares         beneficially owned include the Shares owned by BioSignia. </p>      <p align="left">(2)&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;The calculation of the         percentage of class beneficially owned is based on the 20,838,154 Shares         &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;which were
issued and outstanding at May 1, 2000.<br>        &nbsp;&nbsp;</p>      <p align="left">&nbsp;&nbsp;&nbsp;&nbsp;The following table shows, as of         May 1, 2000 the number of Shares owned by each director and by all directors         and principal officers of the Corporation as a group.
The address of each         of the named individuals below is c/o Paracelsian, Inc., 222 Langmuir         Laboratories, Cornell Technology Park, Ithaca, New York 14850.</p>    </td>  </tr><font face="CG Times, Times New Roman"><br></font> <table width="450" border="0" cellspacing="3" align="center" height="315">  <tr>     <td width="183" valign="bottom">Name of Beneficial Ownner</td>    <td width="12">&nbsp;</td>
    <td width="107">       <div align="center">Shares Currently <br>        Beneficially Owned</div>    </td>    <td width="11">&nbsp;</td>    <td width="115">       <div align="center">Percent of Shares <br>        Beneficially Owned(2) </div>    </td>  </tr>
  <tr>     <td width="183">       <hr noshade>    </td>    <td width="12">&nbsp;</td>    <td width="107">       <hr noshade align="right">    </td>    <td width="11">&nbsp;</td>    <td width="115">       <hr noshade>    </td>  </tr>  <tr>     <td width="183">
&nbsp;</td>    <td width="12">&nbsp;</td>    <td width="107">&nbsp;</td>    <td width="11">&nbsp;</td>    <td width="115">&nbsp;</td>  </tr>  <tr>     <td width="183">T. Colin Campbell</td>    <td width="12">&nbsp;</td>    <td width="107">       <div align="right
">5,753,600</div>    </td>    <td width="11">&nbsp;</td>    <td width="115">       <div align="right">27.61%</div>    </td>  </tr>  <tr>     <td width="183">&nbsp;</td>    <td width="12">&nbsp;</td>    <td width="107">       <div align="right"></div>    </td>
    <td width="11">&nbsp;</td>    <td width="115">       <div align="right"></div>    </td>  </tr>  <tr>     <td width="183">T. Nelson Capbell</td>    <td width="12">&nbsp;</td>    <td width="107">       <div align="right">6,043,897</div>    </td>    <td
width="11">&nbsp;</td>    <td width="115">       <div align="right">29.00%</div>    </td>  </tr>  <tr>     <td width="183">&nbsp;</td>    <td width="12">&nbsp;</td>    <td width="107">       <div align="right"></div>    </td>    <td width="11">&nbsp;</td>    <td
width="115">       <div align="right"></div>    </td>  </tr>  <tr>     <td width="183">Hira Gurtoo</td>    <td width="12">&nbsp;</td>    <td width="107">       <div align="right">35,464</div>    </td>    <td width="11">&nbsp;</td>    <td width="115">       <div
align="right">*</div>    </td>  </tr>  <tr>     <td width="183">&nbsp;</td>    <td width="12">&nbsp;</td>    <td width="107">       <div align="right"></div>    </td>    <td width="11">&nbsp;</td>    <td width="115">       <div align="right"></div>    </td>  </tr>  <tr>
     <td width="183">Lianping He</td>    <td width="12">&nbsp;</td>    <td width="107">       <div align="right">10,646</div>    </td>    <td width="11">&nbsp;</td>    <td width="115">       <div align="right">*</div>    </td>  </tr>  <tr>     <td width="183"
height="14">&nbsp;</td>    <td width="12" height="14">&nbsp;</td>    <td width="107" height="14">       <div align="right"></div>    </td>    <td width="11" height="14">&nbsp;</td>    <td width="115" height="14">       <div align="right"></div>    </td>  </tr>  <tr>
    <td width="183">Thomas D. Livingston</td>    <td width="12">&nbsp;</td>    <td width="107">       <div align="right">245,582</div>    </td>    <td width="11">&nbsp;</td>    <td width="115">       <div align="right">1.18%</div>    </td>  </tr>  <tr>
<td width="183">&nbsp;</td>    <td width="12">&nbsp;</td>    <td width="107">       <div align="right"></div>    </td>    <td width="11">&nbsp;</td>    <td width="115">       <div align="right"></div>    </td>  </tr>  <tr>     <td width="183">All Directors and Principal
Officers as a Group (8 persons)     </td>    <td width="12">&nbsp;</td>    <td width="107">       <div align="right">6,375,624</div>    </td>    <td width="11">&nbsp;</td>    <td width="115">       <div align="right">30.60%</div>    </td>  </tr>  <tr>     <td width="422" colspan="5"
valign="bottom">&nbsp;</td>  </tr>  <tr>     <td width="422" colspan="5" valign="bottom">* Denotes beneficial ownership       of less than one percent of the Shares. </td>  </tr><br><table width="500" border="0" align="center">  <tr>     <td>       <p>(1)&nbsp;
&nbsp;&nbsp;&nbsp;&nbsp;To the Corporations's knowledge, each         person has sole voting and investment power over the Shares shown as beneficially         owned by such person, except for the following Shares which the individual         indicates
that he or she shares voting and/or investment power: Dr. Colin         Campbell - 5,753,600 Shares; Mr. Nelson Campbell - 6,043,897 Shares; and         directors and principal officers as a group - 6,472,482 Shares. Dr. Campbell         and Mr. Campbell
are the principal shareholders of BioSignia and their         total shares beneficially owned include the Shares owned by BioSignia.</p>      <p>(2)&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;The calculation of the percentage of         class beneficially owned is based on the 20,838,154 Shares which were         issued and outstanding at May 1, 2000, plus the number of Shares capable         of
being issued to that individual (if any) and to directors and principal         officers as a group within 60 days of the voting record date upon the         exercise of stock options held by each of them (if any) and by the group,         respectively. </p>      <p align="center"><b>PROPOSAL 1: ELECTION OF DIRECTORS</b></p>      <p align="left">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;The         Corporation's Bylaws provide that the Board shall be divided into three         classes,
each containing as nearly equal a number of directors as possible,         each elected to staggered three-year terms of office and thereafter directors         elected to succeed those directors in each class shall be elected for         a term of office
of three years. The Board has set the number of directors         at seven.</p>      <p align="left"> &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;The         Board has nominated three individuals to be elected as directors at this         Annual Meeting to serve a three year term until the Annual Meeting of
  Shareholders in 2003 ("Class II Directors") and one director to serve         a one year term until the Annual Meeting of Shareholders in the year 2001         ("Class III Directors"), or until their successors are elected and qualified.
Nominees He and Livingston are current Board members who were appointed         to the Board following BioSignia's investment in the Corporation on January         14, 1998. Nominees Shaibe and Inoue were appointed to the Board in February         and
April 2000 respectively. The four nominees receiving the highest number         of votes will be elected. </p>      <p align="left"> &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;In         the absence of any contrary specification, the Proxy Committee will vote         for the election of the three nominees listed below as Class II Directors
     and the one nominee listed below as a Class III Director by casting an         equal number of votes for each nominee. If, at or before the meeting time,         any of the nominees listed below has become unavailable for any reason,         the
Proxy Committee has the discretion to vote for a substitute nominee.         Management currently has no reason to anticipate that any nominee listed         below will become unavailable. </p>      <p align="left"> &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Listed         below are the names of the nominees for election as Class II Directors         and the Class III Director, together with their ages at December 31, 1999,
        and their principal occupations during the past five years. </p>    </td>  </tr><br><table width="450" border="0" cellspacing="3" align="center">  <tr>     <td width="123">Name and Age </td>    <td width="29" align="center" valign="top">&nbsp;</td>    <td width="277">Principal Occupation Over Last Five Years
</td>  </tr>  <tr>     <td width="123">       <hr noshade>    </td>    <td width="29" align="center" valign="top">&nbsp;</td>    <td width="277">       <hr noshade>    </td>  </tr>  <tr>     <td width="123"><i>Class II Directors:</i></td>    <td width="29"
align="center" valign="top">&nbsp;</td>    <td width="277">&nbsp;</td>  </tr>  <tr>     <td width="123">&nbsp;</td>    <td width="29" align="center" valign="top">&nbsp;</td>    <td width="277">&nbsp;</td>  </tr>  <tr>     <td width="123" valign="top">Lianping He</td>    <td
width="29" valign="top" align="center">52</td>    <td width="277">President, Chinese Service Center for Scholarly Exchange,Inc.       and Executive President, New York Service Center forChinese Study Fellows,       Inc. since 1995; prior to that, Director, Chinese Education Association
for International Exchange and Vice President, Chinese Service Center for       Scholarly Exchange, both of Beijing, China </td>  </tr>  <tr>     <td width="123">&nbsp;</td>    <td width="29" align="center" valign="top">&nbsp;</td>    <td width="277">&nbsp;</td>  </tr>  <tr>     <td width="123" valign="top">Thomas D. Livingston</td>    <td width="29" align="center" valign="top">
47</td>    <td width="277">President and Co-founder, TLC Management Corp.; also, Chief       Financial Officer, BioSignia, Inc., Chapel Hill, North Carolina since 1997.     </td>  </tr>  <tr>     <td width="123">&nbsp;</td>    <td width="29" align="center"
valign="top">&nbsp;</td>    <td width="277">&nbsp;</td>  </tr>  <tr>     <td width="123" valign="top">Dr. Mac Shaibe</td>    <td width="29" align="center" valign="top">66</td>    <td width="277">Chairman of the ReGenesis Foundation and President and Chief
Executive Officer of Technology Transfer International.</td>  </tr>  <tr>     <td width="123"><i>Class III Director:</i></td>    <td width="29" align="center" valign="top">&nbsp;</td>    <td width="277">&nbsp;</td>  </tr>  <tr>     <td width="123">&nbsp;</td>    <td width="29" align="center" valign="top">&nbsp;
</td>    <td width="277">&nbsp;</td>  </tr>  <tr>     <td width="123" valign="top">Noriyoshi Inoue</td>    <td width="29" align="center" valign="top">52</td>    <td width="277">Consultant; prior to that, Deputy General Manager and International       Marketing
Manager, Kubota corporation, New York, NY since 1997; prior to       that, International Business Manager and General Manager of Export Department,       Tokoyo, Japan.</td>  </tr><br><table width="500" border="0" cellspacing="3" align="center">  <tr>     <td>       <p>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;The Board         of Directors Recommends That The Shareholders Vote For The Election
of         Each of The Nominees For Director Listed Above. The Four Nominees Receiving         The Highest Number of Votes Will Be Elected.</p>      <p align="center"><b>MANAGEMENT OF THE CORPARATION</b></p>      <p align="left"><b>Board of Directors</b></p>      <p align="left"> &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Listed         below are the names of the Class I
Directors, who were elected at the         1999 Annual Meeting to serve until the Annual Meeting in 2002, together         with their ages at December 31, 1999, and their principal occupations         during the past five years. </p>    </td>  </tr><br><table width="450" border="0" cellspacing="3" align="center">  <tr>     <td width="123">Name and Age </td>    <td width="29" align="center" valign="top">&nbsp;</td>    <td width="277">Principal Occupation Over Last Five Years
</td>  </tr>  <tr>     <td width="123">       <hr noshade>    </td>    <td width="29" align="center" valign="top">&nbsp;</td>    <td width="277">       <hr noshade>    </td>  </tr>  <tr>     <td width="123">&nbsp;</td>    <td width="29" align="center"
valign="top">&nbsp;</td>    <td width="277">&nbsp;</td>  </tr>  <tr>     <td width="123" valign="top">T. Nelson Campbell</td>    <td width="29" valign="top" align="center">34</td>    <td width="277">Chairman, BioSignia, Inc. Chapel Hill, North Carolina since
1996; prior to that, Vice President, Paracelsian, Inc. from 1995 to 1996;       prior to that, President, Pacific Liaisons, Ithaca, NY (until its merger       into Paracelsian in 1995).</td>  </tr>  <tr>     <td width="123" valign="top">&nbsp;</td>    <td width="29" valign="top" align="center">&nbsp;</td>    <td width="277">&nbsp;</td>  </tr>  <tr>     <td width="123" valign="top">Hira Gurtoo</td>    <td width="29" valign="top"
align="center">60</td>    <td width="277">President, Professional Financial Advisers, Inc., Amherst,       New York; also, Cancer Research Scientist, Roswell Park Cancer Institute,       Buffalo, New York until February 1998.</td>  </tr><p align="center">&nbsp;
</p><table width="500" border="0" align="center">  <tr>     <td>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Listed below       is the name of the other Class III Director, who was elected at the 1998       Annual Meeting to serve until the
Annual Meeting in 2001, together with       his age at December 31, 1999, and his principal occupation during the past       five years. </td>  </tr><br><table width="450" border="0" cellspacing="3" align="center">  <tr>     <td width="123">Name and Age </td>    <td width="29" align="center" valign="top">&nbsp;</td>    <td width="277">Principal Occupation Over Last Five Years</td>
</tr>  <tr>     <td width="123">       <hr noshade>    </td>    <td width="29" align="center" valign="top">&nbsp;</td>    <td width="277">       <hr noshade>    </td>  </tr>  <tr>     <td width="123">&nbsp;</td>    <td width="29" align="center" valign="top">
&nbsp;</td>    <td width="277">&nbsp;</td>  </tr>  <tr>     <td width="123" valign="top">T. Colin Campbell</td>    <td width="29" valign="top" align="center">64</td>    <td width="277">President and Chief Executive Officer, Paracelsian, since       January 2000;
 also, Jacob Gould Schurman Professor of Nutritional Sciences,       Cornell University, Ithaca. NY; Founder and Director, Pacific Health Laboratories       (Nasdaq Symbol PHLI) since 1995; Founder and Director, BioSignia, Inc.,       Chapel Hill, North
Carolina. </td>  </tr><p align="left">&nbsp;</p><table width="500" border="0" align="center">  <tr>     <td>       <p>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Other than         Dr. Campbell and Mr. Campbell, who are father and son, no
proposed director         or principal officer is related to another director or officer. Other         than Dr. Campbell, no proposed director is a director of any company with         a class of securities registered pursuant to Section 12 of the
Securities         Exchange Act of 1934, as amended (the "Exchange Act").</p>      <p><b>Reports of Beneficial Ownership</b></p>      <p> &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Directors         and principal officers of the Corporation are required by federal law         to file reports with the
Securities Exchange Commission regarding the         amount of and changes in their beneficial ownership of the Shares. To         the Corporation's knowledge, all such required reports have been timely         filed.</p>      <p><b>Board Attendance, Fees and Committees</b></p>      <p>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;During the         fiscal year ended September 30, 1999 ("Fiscal Year 1999"), the Board had         held ten meetings, two
requiring personal attendance and eight telephone         meetings. All the directors were present for at least seventy-five percent         of these meetings except director He, who attended one of the meetings.         During Fiscal Year 1999, the
non-employee members of the Board of Directors         received $3,000 per meeting requiring personal attendance and $750 per         meeting by telephone. All fees were paid in Shares. For Fiscal Year 2000,         the fees will remain the same. The
Board has only established an Executive         Committee to date. The Executive Committee, between Board meetings and         subject to such limitations as may be required by law or imposed by Board         resolution, may exercise all of the Board's
authority. The Executive Committee         also performs the functions of a nominating committee. The Executive Committee's         nominating committee functions include, among other things, recommending         annually to the Board the names of persons
to be considered for nomination         and election by the Corporation's shareholders and, as necessary, recommending         to the Board the names of persons to be elected to the Board to fill vacancies         as they occur between annual meetings. In
identifying prospects for the         Board, the Committee will consider individuals recommended by shareholders.         Names and resumes of nominees should be forwarded to the Corporate Secretary         who will submit them to the Executive Committee
for consideration. The         Executive Committee held one meetings during Fiscal Year 1999. The Executive         Committee presently consists of directors Nelson Campbell, Dr. Colin Campbell,         and Thomas Livingston</p>      <p>&nbsp;</p>    </td>  </tr><p align="left">&nbsp;</p><p align="center">&nbsp;</p><p align="center">&nbsp;</p><p align="center">&nbsp;</p><p align="center">&nbsp;</p><p align="center">&nbsp;</p><p align="center">&nbsp;</p><p align="center
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