SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON, D.C. 20549

                                    FORM 10-K


   X     ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES 
         EXCHANGE ACT OF 1934 FOR THE FISCAL YEAR ENDED DECEMBER 31, 1997, OR

         TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES
         EXCHANGE ACT OF 1934 FOR THE TRANSITION PERIOD FROM ____________ TO
         _____________.


                         Commission File Number: 0-20199

                              EXPRESS SCRIPTS, INC.
             (Exact name of registrant as specified in its charter)

            DELAWARE                                 43-1420563
  (State or other jurisdiction          (I.R.S. employer identification no.)
  incorporation or organization)

14000 RIVERPORT DR., MARYLAND HEIGHTS, MISSOURI                  63043
(Address of principal executive offices)                       (Zip Code)

       Registrant's telephone number, including area code: (314) 770-1666

           Securities registered pursuant to Section 12(b) of the Act:

                                      None

           Securities registered pursuant to Section12(g) of the Act:

                      CLASS A COMMON STOCK, $0.01 PAR VALUE
                                (Title of Class)

     Indicate  by check mark  whether the  registrant  (1) has filed all reports
required to be filed by Section 13 or 15(d) of the  Securities  Exchange  Act of
1934  during  the  preceding  12 months  (or for such  shorter  period  that the
registrant was required to file such reports),  and (2) has been subject to such
filing requirements for the past 90 days. Yes X No___

     Indicate by check mark if disclosure of delinquent  filers pursuant to Item
405 of Regulation of S-K is not contained herein, and will not be contained,  to
the  best  of  Registrant's   knowledge,  in  definitive  proxy  or  information
statements  incorporated  by  reference  in Part  III of this  Form  10-K or any
amendment to this Form 10-K. [X]

     The  aggregate   market  value  of   Registrant's   voting  stock  held  by
non-affiliates  as of March 6, 1998,  was  $752,939,788  based on 9,238,525 such
shares held on such date by non-affiliates and the last sale price for the Class
A Common Stock on such date of $81.50 as reported on the Nasdaq National Market.
Solely for purposes of this  computation,  the  Registrant  has assumed that all
directors  and  executive  officers  of the  Registrant  and  NYLIFE  HealthCare
Management, Inc. are affiliates of the Registrant.

Common stock outstanding as of March 9, 1998:    9,269,270  Shares Class A
                                                 7,510,000  Shares Class B

                       DOCUMENTS INCORPORATED BY REFERENCE

     Part  III  incorporates  by  reference  portions  of the  definitive  proxy
statement for the  Registrant's  1998 Annual Meeting of  Stockholders,  which is
expected to be filed with the Securities and Exchange  Commission not later than
120  days  after  the   registrant's   fiscal  year  ended  December  31,  1997.



                                     PART I

                                   THE COMPANY

ITEM 1 - BUSINESS

     INFORMATION  INCLUDED OR INCORPORATED BY REFERENCE IN THIS ANNUAL REPORT ON
FORM 10-K, AND INFORMATION THAT MAY BE CONTAINED IN OTHER FILINGS BY THE COMPANY
WITH THE  SECURITIES AND EXCHANGE  COMMISSION  (THE  "COMMISSION")  AND RELEASES
ISSUED OR STATEMENTS MADE BY THE COMPANY, CONTAIN OR MAY CONTAIN FORWARD-LOOKING
STATEMENTS,  INCLUDING BUT NOT LIMITED TO  STATEMENTS  OF THE  COMPANY'S  PLANS,
OBJECTIVES,   EXPECTATIONS  OR  INTENTIONS.   SUCH  FORWARD-LOOKING   STATEMENTS
NECESSARILY  INVOLVE RISKS AND  UNCERTAINTIES.  THE COMPANY'S ACTUAL RESULTS MAY
DIFFER  SIGNIFICANTLY  FROM THOSE PROJECTED OR SUGGESTED IN ANY  FORWARD-LOOKING
STATEMENTS. FACTORS THAT MIGHT CAUSE SUCH A DIFFERENCE TO OCCUR INCLUDE, BUT ARE
NOT LIMITED TO: HEIGHTENED COMPETITION, INCLUDING INCREASED PRICE COMPETITION IN
THE  PHARMACY  BENEFIT  MANAGEMENT  BUSINESS;  THE POSSIBLE  TERMINATION  OF THE
COMPANY'S  CONTRACTS  WITH CERTAIN KEY  CLIENTS;  CHANGES IN PRICING OR DISCOUNT
PRACTICES  OF  PHARMACEUTICAL  MANUFACTURERS;  THE  ABILITY  OF THE  COMPANY  TO
CONSUMMATE CONTRACT  NEGOTIATIONS WITH PROSPECTIVE  CLIENTS;  COMPETITION IN THE
BIDDING  AND  PROPOSAL  PROCESS;  ADVERSE  RESULTS  IN  CERTAIN  LITIGATION  AND
REGULATORY  MATTERS;  THE ADOPTION OF ADVERSE  LEGISLATION  OR  REGULATIONS OR A
CHANGE IN THE INTERPRETATION OF EXISTING LEGISLATION OR REGULATIONS;  THE IMPACT
OF INCREASES IN HEALTH CARE COSTS AND  UTILIZATION  PATTERNS;  RISKS  ASSOCIATED
WITH THE DEVELOPMENT OF NEW PRODUCTS;  RISKS ASSOCIATED WITH THE CONSUMMATION OF
ACQUISITIONS,  INCLUDING THE ABILITY TO SUCCESSFULLY INTEGRATE THE OPERATIONS OF
ACQUIRED  BUSINESSES  WITH THE  EXISTING  OPERATIONS  OF THE  COMPANY  AND RISKS
INHERENT IN THE ACQUIRED  ENTITIES  OPERATIONS;  AND OTHER RISKS  DESCRIBED FROM
TIME TO TIME IN THE COMPANY'S FILINGS WITH THE COMMISSION.  THE COMPANY DOES NOT
UNDERTAKE   ANY   OBLIGATION   TO  RELEASE   PUBLICLY  ANY   REVISIONS  TO  SUCH
FORWARD-LOOKING  STATEMENTS TO REFLECT  EVENTS OR  CIRCUMSTANCES  AFTER THE DATE
HEREOF OR TO REFLECT THE OCCURRENCE OF UNANTICIPATED EVENTS.

COMPANY OVERVIEW

     Express  Scripts,  Inc.  ("ESI" or the  "Company")  is a leading  specialty
managed  care  company  and  one of the  largest  independent  pharmacy  benefit
managers ("PBMs") in North America,  providing a broad range of pharmacy benefit
management ("PBM") services to health benefit plan sponsors,  with approximately
12.3 million health plan members  currently  enrolled in ESI's PBM programs.  In
addition  to its  PBM  services,  the  Company  offers  (i)  disease  management
services,  (ii) informed decision counseling services through its Express Health
LineSM division ("Health Line"), (iii) medical information  management services,
which  include  provider  profiling,  disease  management  support  services and
outcomes  assessments,  through its  Practice  Patterns  Science,  Inc.  ("PPS")
subsidiary,  (iv)  pharmaceuticals  for and the  provision  of infusion  therapy
services  through  its IVTx  division  ("IVTx"),  and (v)  managed  vision  care
programs through its Express Scripts Vision Corporation subsidiary ("Vision").

     The  Company  was  incorporated  in Missouri  in  September  1986,  and was
reincorporated  in Delaware in March 1992. The Company has two classes of common
stock,  Class A Common Stock and Class B Common Stock. Each share of the Class B
Common  Stock is  entitled  to ten  votes,  and each share of the Class A Common
Stock is entitled to one vote. All of the issued and  outstanding  shares of the
Class B Common Stock are owned by NYLIFE  HealthCare  Management,  Inc. ("NYLIFE
HealthCare"),  which  is an  indirect  subsidiary  of New  York  Life  Insurance
Company,  a mutual life insurance  company organized and existing under the laws
of the State of New York ("New York Life").  The Company's  principal  executive
offices are located at 14000 Riverport Drive, Maryland Heights,  Missouri 63043,
and its telephone number is (314) 770-1666.

     To date,  the Company's  internal  growth has been  primarily the result of
sales to new clients, sales of new services to existing clients, and the general
growth  of  existing  clients,  as the  Company's  PBM  revenues  are  driven by
increased  network and mail  pharmacy  claim volume.  On February 20, 1998,  the
Company  announced  that it had  executed a  definitive  agreement  to  purchase
ValueRx,  the PBM  business of  Columbia/HCA  Healthcare  corporation,  for $445
million.  When completed,  the Company  believes that it will be the largest PBM
that  is  independent  of  pharmaceutical   manufacturer   ownership.   As  more
particularly  discussed  herein in Item 7,  consummation  of the  transaction is
subject to customary closing conditions and regulatory approval, but is expected
to occur during the second quarter of 1998.

PRODUCTS AND SERVICES

PHARMACY BENEFIT MANAGEMENT SERVICES

     The Company's PBM service involves the systematic  management of outpatient
prescription  drug usage to foster high quality,  cost-effective  pharmaceutical
care through the application of managed care principles and advanced information
technologies. The Company offers core and advanced PBM services to its customers
in the U.S. and Canada.  Core PBM services  consist of retail  pharmacy  network
administration;   formulary  administration;   electronic  point-of-sale  claims
processing;  drug utilization review ("DUR"); mail pharmacy service; and benefit
plan  design  consultation.  Approximately  79.6% of the  members  served by the
Company  have access to  prescription  drugs both  through one of the  Company's
retail pharmacy  networks and through its mail pharmacy  facilities,  reflecting
the Company's emphasis on providing fully integrated pharmacy services.  As part
of its ongoing commitment to provide cost containment solutions for its clients,
the Company also offers advanced PBM services. Advanced PBM services include the
development  of  advanced  formulary  compliance  and  therapeutic  substitution
programs;  therapy  management  services  such as prior  authorization,  therapy
guidelines,  step therapy protocols, and disease management  interventions;  and
sophisticated management information reporting and analytic services.

     CORE PHARMACY BENEFIT MANAGEMENT SERVICES

     The Company contracts with retail pharmacies to provide  prescription drugs
to members of the pharmacy  benefit plans  managed by the Company.  In the U.S.,
these pharmacies  typically  discount the price at which they will provide drugs
to members in return for designation as a network pharmacy.  The Company manages
three  nation-wide  networks in the U.S. and one  nation-wide  network in Canada
that are  responsive  to client  preferences  related  to cost  containment  and
convenience  of access  for  members.  The  Company  also  manages  networks  of
pharmacies  that are under  direct  contract  with its managed  care  clients or
networks that ESI has designed to meet the specific  needs of some of its larger
clients.

     The Company uses on-line  electronic claims processing to provide effective
PBM services to its clients.  All retail  pharmacies in the  Company's  pharmacy
networks  communicate  with the  Company  on-line  and in real  time to  process
prescription  drug  claims.  When  a  member  of a  plan  presents  his  or  her
identification  card at a network  pharmacy,  the network  pharmacist  sends the
specified  claim  data in an  industry  standard  format  to the  Company  which
processes  the claim and responds to the pharmacy,  typically  within one or two
seconds. The electronic processing of the claim involves confirming the member's
eligibility  for  benefits  under the  applicable  health  benefit  plan and the
conditions to or  limitations  of coverage,  such as the amount of copayments or
deductibles  the member must pay;  performing  a  concurrent  DUR  analysis  and
alerting the pharmacist to possible drug  interactions  or other  indications of
inappropriate  prescription drug usage;  updating the member's prescription drug
claim record; and, if the claim is accepted,  confirming to the pharmacy that it
will receive payment for the drug dispensed.

     The Company  integrates its pharmacy network benefits with its mail service
pharmacy  benefits  provided  to its  clients.  It  operates  two  mail  service
pharmacies,  one located in  Missouri  and the other in  Arizona,  that  provide
members  with  convenient  access to  maintenance  medications,  and  enable the
Company and its clients to control drug costs through operating efficiencies and
economies  of scale.  In  addition,  through its mail  service  pharmacies,  the
Company is able to be directly  involved with the prescriber and member,  and is
generally   able  to  achieve  a  higher   level  of  generic  and   therapeutic
substitutions  than can be achieved through the retail pharmacy  network,  which
further reduces the client's costs.

     Core PBM  services  also  involve  benefit  plan  design  and  consultation
services.  The Company offers  consultation and financial  modeling  services to
assist the customer in selecting a benefit plan design that meets the customer's
needs for member  satisfaction and cost control.  The most common benefit design
options offered by the Company are member  financial  incentives and limitations
on the drugs covered by the plan, including drug formularies;  copayments, which
may be a flat dollar  amount or a  percentage  of the cost of the  prescription;
deductibles or annual benefit  maximum;  generic drug  substitution  incentives;
incentives or  requirements  to use only network  pharmacies or to order certain
drugs only by mail; and  limitations on the number of days supply of a drug that
can be obtained.  The  selected  benefit  design is entered  into the  Company's
electronic  claims processing  system,  which enforces the plan design as claims
are  submitted  and enables the Company and its clients to monitor the financial
performance of the plan.

     During 1997, 67.4% of the Company's net revenues were derived from pharmacy
network and claims administration  services,  compared to 67.0% and 66.2% during
1996 and 1995,  respectively.  The  number of claims  processed  by the  Company
through its pharmacy  networks has  increased  from  approximately  18.3 million
claims in 1993 to  approximately  73.2 million  claims in 1997.  During 1996 and
1995,  the Company  processed  57.8  million and 42.9 million  pharmacy  network
claims,  respectively.  During 1997,  28.6% of the  Company's  net revenues were
derived from mail pharmacy services, compared to 28.7% and 29.7% during 1996 and
1995, respectively.  The number of mail prescriptions processed by the Company's
mail pharmacy  service has increased from  approximately  1.2 million in 1993 to
3.9 million in 1997. During 1996 and 1995, the Company processed 2.8 million and
2.1 million mail pharmacy prescriptions, respectively.

     ADVANCED PHARMACY BENEFIT MANAGEMENT SERVICES

     The Company provides advanced PBM services to its clients which involve the
application  of clinical  expertise  and  sophisticated  management  information
systems to manage the pharmacy benefit. An important PBM service provided by the
Company is the  enhancement of formulary  compliance.  Formularies  are lists of
drugs for which coverage is provided under the applicable  plan; they are widely
used in managed  healthcare  plans and,  increasingly,  by other healthcare risk
managers.  The Company  administers  a number of different  formularies  for its
clients that often identify  preferred drugs whose use is encouraged or required
through  various  benefit  design  features.  Historically,  many  clients  have
selected a plan design which  includes an open  formulary in which all drugs are
covered by the plan and preferred  drugs, if any, are merely  recommended.  More
advanced  formularies  consist  of  restricted  formularies,  in  which  various
financial or other  incentives  exist for the selection of preferred  drugs over
their non-preferred  counterparts,  or closed formularies, in which benefits are
available only for drugs listed on the formulary.  Formulary  preferences can be
encouraged by  restricting  the formulary  through plan design  features such as
tiered  copayments,  which  require  the  member  to pay a higher  amount  for a
nonpreferred drug; through prescriber  education programs,  in which the Company
or the managed care client  actively seek to educate the  prescribers  about the
formulary  preferences;  and  through  the  Company's  ExpressPreferenceSM  drug
therapy  management  program,  which actively  promotes  therapeutic and generic
interchanges    to   reduce    drug    costs.    The    Company    also   offers
ExpressTherapeuticsSM,  an innovative  proprietary DUR and clinical intervention
program,  to assist  clients in managing  compliance  with the  prescribed  drug
therapy and inappropriate prescribing practices.

     ESI's  National  Pharmacy and  Therapeutics  Committee  (the  "Committee"),
composed of physicians and pharmacists,  evaluates drugs to determine whether it
is clinically appropriate to give formulary preference to one drug over another.
If clinical appropriateness is established to the Committee's satisfaction,  the
Committee  also  considers the  cost-effectiveness  of drugs in the same therapy
class. Once a client adopts a formulary,  the Company  administers the formulary
through the electronic claims processing system,  which alerts the pharmacist if
the prescriber  has not  prescribed the preferred  drug. The pharmacist can then
contact the prescriber to attempt to obtain the  prescriber's  consent to switch
the prescription to the preferred product.

     Through  the   development   of   increasingly   sophisticated   management
information and reporting  systems,  the Company manages the  prescription  drug
benefit more effectively. The Company has developed an on-line prescription drug
decision  support  tool  called  RxWorkbenchTM  that  enables the Company or the
client to analyze  prescription drug data to identify cost trends and budget for
expected drug costs,  to assess the financial  impact of plan design changes and
to  identify  costly  utilization  patterns.  These  systems  permit a medically
sophisticated  user,  such  as  a  clinical  pharmacist  employed  by  a  health
maintenance organization ("HMO"), to analyze prescription drug data on-line.

     The  Company's  electronic  claims  processing  system  also  enables it to
implement sophisticated intervention programs to assist in managing prescription
drug utilization.  The system can be used to alert the pharmacist to generic and
therapeutic  substitution  opportunities and formulary  compliance issues, or to
administer prior authorization and step-therapy  protocol programs at the time a
claim is submitted for processing.  The Company's claims  processing system also
creates a database of drug utilization  information that can be accessed both at
the time the  prescription  is dispensed  and also on a  retrospective  basis to
analyze   utilization  trends  and  prescribing   patterns  for  more  intensive
management of the drug benefit.

OTHER SERVICES

     In addition to PBM services,  the Company also provides disease  management
services,  informed decision counseling services, medical information management
services, infusion therapy services and vision care services to its clients. Net
revenues to the Company from non-PBM services  represented  approximately  $49.7
million in 1997, $33.1 million in 1996, and $22.2 million in 1995.

     DISEASE MANAGEMENT SERVICES

     In late 1997, the Company began  offering  disease  management  programs to
assist health benefit plans in managing the total  healthcare  costs  associated
with  certain  diseases,  such as asthma,  diabetes  and  cardiovascular.  These
programs are based upon the premise  that  patient and provider  behavior can be
positively  influenced  to  improve  health and reduce  overall  medical  costs.
Patient  identification  can be  accomplished  through  claim data  analysis  or
self-enrollment,  and risk  stratification  surveys are conducted to establish a
plan of care for individual program participants. Patient education is primarily
effected  through a series of telephone and written  communications  from nurses
and  pharmacists,  and both providers and patients receive progress reports on a
regular basis. Outcome surveys are conducted and results are compiled to analyze
the clinical, humanistic and economic impact of the program.

     INFORMED DECISION COUNSELING SERVICES - EXPRESS HEALTH LINESM

     The Company began offering  healthcare decision counseling services through
its Express  Health LineSM  division  during the second  quarter of 1997, and by
year-end  was  providing   service  to   approximately   1.3  million   members.
Specifically,  this service allows a member to call a toll-free telephone number
and discuss a  healthcare  matter with a care  counselor  who  utilizes  on-line
decision support  protocols and other  guidelines to provide  information to the
member to allow the member to make an informed  decision in seeking  appropriate
treatment. Records of each call are maintained on-line for future reference. The
service  is  available  24 hours  per  day,  365  days  per  year.  Multilingual
capabilities  and service  for the  hearing  impaired  are also  available.  The
counselors  provide follow-up service to members to determine if their situation
was  resolved or if the  counselor  may provide  additional  assistance.  Member
satisfaction and outcome  assessment are tracked by the use of member surveys, a
quality assurance plan and system reports.

     MEDICAL INFORMATION MANAGEMENT - PRACTICE PATTERNS SCIENCE, INC. ("PPS")

     The success of the Company's disease  management  programs will continue to
depend,  in part, on the development of sophisticated  information  systems that
can identify  members for  participation  in such  programs and then measure the
results of the  program.  PPS,  the  Company's  medical  information  management
subsidiary,  offers provider profiling, disease management support services, and
outcomes assessments, and has developed proprietary software to process and sort
medical claim,  prescription drug claim, and clinical laboratory data to produce
comprehensive  information  about  treatment  of  patients  that  can be used by
managed care  organizations and other companies  involved in disease  management
programs (including pharmaceutical  manufacturers and medical care providers) to
treat a  particular  disease in a quality,  cost  effective  manner.  By linking
together  all  services  provided to a  particular  member to treat a particular
medical condition and comparing such data to data in PPS's normative  databases,
PPS can assess the  effectiveness  of treatment and calculate the total costs of
that treatment.

     Clients  of PPS,  including  the  Company,  will  use the  information  PPS
develops to monitor the effectiveness of disease management programs and compute
and manage total healthcare costs, including prescription drug costs, for health
plan sponsors. The information can also be used to analyze the practice patterns
of healthcare providers and develop empirically-based "best practice" protocols,
which recommend a treatment regimen for specific diseases.

     OUTPATIENT INFUSION THERAPY SERVICES - IVTX

     Infusion therapy services involve the  administration of prescription drugs
and other  products to a patient by  catheter,  feeding  tube or  intravenously.
IVTx's   clients,   which  include  managed  care   organizations,   third-party
administrators,  insurance  companies,  case  management  companies,  unions and
self-insured  employers,  benefit  from  outpatient  infusion  therapy  services
because the length of  hospital  stays can be  reduced.  Rather  than  receiving
infusion  therapy in a hospital,  IVTx can provide  infusion therapy services to
patients at home, in a physician's office or in a free-standing  center operated
by a managed care  organization  or other entity.  IVTx provides  antimicrobial,
cardiovascular,    hematologic,   nutritional,   analgesic,    chemotherapeutic,
hydration,  endocrine,  respiratory and AIDS management  treatments to patients.
IVTx  typically   prepares  the  treatments  in  one  of  its  infusion  therapy
pharmacies,  which are licensed  independently  of the  Company's  mail services
pharmacies.  The treatments  are either  administered  under the  supervision of
IVTx's staff of registered nurses or licensed vocational nurses who are employed
at one of the IVTx sites or, in areas  where IVTx does not have a  facility,  it
contracts for services of registered  nurses  employed or otherwise  retained by
nursing  agencies,  who administer  the  treatment.  IVTx may also contract with
physicians to provide medical  director  services to its sites, and contract for
pharmacy services for patients who live in outlying areas.

     The Company has facilities  supporting its infusion  therapy  operations in
Houston, Texas; Dallas, Texas; Columbia,  Maryland;  Maryland Heights, Missouri;
Northvale,  New Jersey;  Tempe, Arizona and West Chester,  Pennsylvania.  IVTx's
information  system maintains  patient profiles and documents doses and supplies
dispensed, and its DUR component accesses ESI's prescription records for members
receiving  both infusion and oral drug  therapies from the Company to screen for
drug interactions, incompatibilities and allergies.

     VISION CARE SERVICES

     The  Company  offers a managed  vision  care  program  through a network of
approximately 9,000 vision care providers,  consisting primarily of optometrists
and a smaller number of  ophthalmologists.  Several  providers  offer service at
multiple locations, thereby allowing members to access the Company's vision care
product at approximately 8,500 locations in 49 states. The providers have agreed
to  provide,  at  specific  rates  or  discount  schedules,   a  routine  vision
examination and eyewear (including contact lenses),  to members of the Company's
managed vision care plans. In addition to administering the network, the Company
grinds and edges lenses and assembles eyeglasses, and distributes eyeglasses and
contact  lenses from its vision lab located in Earth  City,  Missouri,  near the
Company's headquarters.

     The Company  generally  sends its eyeglasses and contact lenses directly to
the local optometrist after  fabrication.  The quality of eyewear  fabricated at
the Company's optical lab meets or exceeds the standard for prescription eyewear
set by the Food and  Drug  Administration  according  to the  American  National
Standards  Institute's  policy for prescription  tolerance.  The Company manages
vision care benefits through its management  information  system which maintains
member  eligibility  information,  verifies  covered  benefits  and charges plan
participants  in accordance  with the provisions of the applicable  vision plan.
Additionally,  the system is used to bill clients and  provides  reports to help
clients manage the optical benefit.

SUPPLIERS

     The Company  maintains an extensive  inventory  in its mail  pharmacies  of
brand and generic pharmaceuticals.  If a pharmaceutical is not in its inventory,
the Company can generally  obtain it from a supplier  within one to two business
days.  The  Company   purchases  its   pharmaceuticals   either   directly  from
manufacturers or through  wholesalers.  During 1997,  approximately 66.0% of the
Company's  pharmaceutical  purchases were through one wholesaler,  most of which
were brand name pharmaceuticals. Generic pharmaceuticals are generally purchased
directly from  manufacturers.  The Company believes that alternative  sources of
supply for both generic and brand name pharmaceuticals are readily available.

CLIENTS

     The  Company  is a major  provider  of PBM  services  to the  managed  care
industry,  including  several large U.S.  HMOs.  Some of the  Company's  largest
managed care clients include NYLCare Health Plans, Inc. ("NYLCare") and Coventry
Corporation  ("Coventry").  As of January 1,  1998,  approximately  46.4% of the
members  receiving  ESI's PBM  services  are members of HMOs.  The Company  also
markets its PBM services  through  preferred  provider  organizations  ("PPOs"),
group  purchasing   organizations   ("GPOs"),   health   insurers,   third-party
administrators of health plans ("TPAs"),  employers and union-sponsored  benefit
plans.

     In 1994,  the Company  entered  into a  strategic  alliance  with  Coventry
Corporation   ("Coventry"),   an  operator  of  HMOs  located  in  Pennsylvania,
Tennessee, Mississippi, and Missouri. Coventry received 25,000 shares of Class A
Common Stock at the time it entered into an exclusive  three-year  agreement for
PBM services that commenced January 1, 1995. In December,  1997, the Company and
Coventry  agreed to a two year extension of their  agreement (with an additional
one year  extension upon the  occurrence of certain  conditions),  in connection
with which the Company issued, as an advance discount,  a seven-year  warrant to
purchase an  additional  25,000  shares of the  Company's  Class A Common Stock,
exercisable  at a price of $52.9088 per share (90% of the per share market value
at  the  time  of  renewal).  See  Note 2 of  Notes  to  Consolidated  Financial
Statements in Item 8 herein for additional discussion concerning Coventry.

     On December 31, 1995, the Company  entered into a series of agreements with
American  HealthCare  Systems  Purchasing  Partners,  L.P. (now known as Premier
Purchasing  Partners,  L.P.; the  "Partnership"),  a healthcare group purchasing
organization  affiliated with APS Healthcare,  Inc. (now known as Premier, Inc.;
"Premier").  Premier is the largest voluntary  healthcare  alliance in the U.S.,
formed as a result of the mergers in late 1995 of three  predecessor  alliances,
American HealthCare Systems, Premier Health Alliance and SunHealth Alliance. The
Premier alliance includes more than 240 integrated  healthcare  systems that own
or operate  approximately  750 hospitals and are  affiliated  with another 1,080
hospitals. Among other things, the agreements designate the Company as Premier's
exclusive  preferred  provider of  outpatient  PBM services to  shareholders  of
Premier and their  affiliated  healthcare  entities,  plans and facilities which
participate in the Partnership's  purchasing programs. The term of the agreement
is ten years,  subject to early  termination  by the  Partnership at five years,
upon payment of an early termination fee to the Company.  Premier is required to
promote the Company as the preferred PBM provider.  An individual Premier member
or affiliated  managed care plan is not required to enter into an agreement with
the  Company,  but if it does so,  the term of the  agreement  would be for five
years.

     As a result of the number of Premier plan members that receive PBM services
from the Company and the outcome of certain joint drug  purchasing  initiatives,
the Company issued 227,273 shares of its Class A Common Stock to the Partnership
in May, 1996.  The  Partnership  could also become  entitled to receive up to an
additional   2,250,000   shares,   depending   on  the   number  of  members  in
Premier-affiliated  managed  care  plans that  contract  for the  Company's  PBM
services. If the Partnership earns stock totaling over 5% of the Company's total
voting stock, it is entitled to have its designee  nominated for election to the
Board.  Under the terms of the agreements with the Partnership,  the Company now
provides  service  to a number  of  Premier  affiliates.  See Note 2 of Notes to
Consolidated  Financial  Statements in Item 8 herein for  additional  discussion
concerning Premier.

     In January,  1996,  the Company  acquired  the  pharmacy  claim  processing
business of Eclipse  Claims  Services,  Inc.,  one of the largest  processors of
prescription  drug claims in Canada.  In connection with this  acquisition,  the
Company  entered into five-year  exclusive  contracts to provide PBM services in
Canada to both Prudential  Insurance  Company of America's  Canadian  Operations
("Prudential")  and  Aetna  Life  Insurance  Company  of  Canada  ("Aetna").  In
addition,  the Company also entered into a ten-year  strategic alliance with The
Manufacturers Life Insurance Company ("Manulife"), the largest provider of group
health  insurance  policies  in  Canada,  pursuant  to which the  Company is the
exclusive  provider of PBM services to Manulife.  As a result of this  alliance,
Manulife can earn up to  approximately  237,000  shares of Class A Common Stock,
depending on its  achievement  of certain  pharmacy  claim  volumes from 1996 to
2000.  If Manulife  does not terminate the agreement in either year 6 or year 10
of the  agreement on each such occasion it will receive a warrant to purchase up
to 118,000  shares of Class A Common Stock  exercisable  at 85% of the then fair
market  value of such  shares.  The  actual  number  of  shares  entitled  to be
purchased  will depend upon claims volume in such years.  See Note 2 of Notes to
Consolidated  Financial  Statements in Item 8 herein for  additional  discussion
concerning Manulife. In addition,  the Company continues to provide PBM services
in Canada to Crown Life Insurance Company.

     The assets of Prudential were previously  acquired by London Life Insurance
Company ("London Life"),  with whom the Company reached an agreement whereby the
Company would be the exclusive  provider of PBM services to London Life. In late
1997, London Life was acquired by Great-West Lifeco.  Inc.  ("Great-West"),  who
receives  PBM  services  from  one  of  the  Company's  competitors  in  Canada.
Great-West  has  indicated  its  intention  not to continue to use the Company's
services,  and the parties are discussing a transition  period and settlement at
this time.

     The Company  also  provides  PBM  services,  informed  decision  counseling
services,  managed  vision care services and infusion  therapy  services to HMOs
owned or managed by NYLCare,  which is an indirect  subsidiary of New York Life,
and provides PBM services to insurance plans  underwritten  and  administered by
NYLCare (these plans were  underwritten  and administered by New York Life prior
to its internal reorganization pursuant to which it transferred all of its group
life and  health  insurance  business,  along  with its PBM  agreement  with the
Company,  to NYLCare;  the  "Indemnity  PBM  Services").  Of the  Company's  net
revenues from PBM services in 1997,  15.7% was for services  provided to members
of HMOs  owned or  managed by NYLCare  or  insurance  policies  administered  by
NYLCare.  Of the  Company's  net  revenues  for managed  vision  care,  informed
decision  counseling  and  infusion  therapy  services,  56.6% was for  services
provided to members of HMOs owned or managed by NYLCare and  insurance  policies
administered  by  NYLCare.  See  Note  3  of  Notes  to  Consolidated  Financial
Statements in Item 8 herein for additional  discussion  concerning NYLCare.  New
York Life recently announced its sale of NYLCare to Aetna U.S. HealthCare,  Inc.
("Aetna"),  and, in connection therewith,  the parties have reached agreement to
extend the HMO PBM and infusion  therapy  agreements  through December 31, 2003,
with new pricing to take effect after  December  31,  1999.  The vision care and
informed decision counseling agreements will continue through December 31, 1999,
and the Company  will also  continue  to provide PBM  services to members of the
NYLCare  indemnity  programs until such members are converted to Aetna policies.
See Item 7 herein for additional disclosures concerning this matter.

COMPANY OPERATIONS

     SALES AND MARKETING;  CLIENT SERVICE.  The Company markets its PBM services
in  the  United  States  through  an  internal   staff  of  national   marketing
representatives and sales personnel and through  independent  regional marketing
representatives  located in certain  cities  across  the  United  States.  These
marketing   representatives   are  supported  by  a  staff  of  client   service
representatives  located in the Company's Missouri and Arizona  facilities.  The
Company's sales and marketing  personnel and client service  representatives are
organized  by type of business  served  (i.e.,  managed  care group,  commercial
client   group,   etc.).   Marketing   in  Canada  is   conducted  by  marketing
representatives  located in Mississaugua,  Ontario,  who are assisted by Company
personnel  based in the U.S. Each of the Company's  U.S.  facilities  contains a
mail service  pharmacy,  client  service,  member service and pharmacy help desk
capabilities,  and  full  electronic  pharmacy  claim  processing  capabilities,
including pharmacy payment capabilities.  At its Canadian facility,  the Company
has client  services and pharmacy help desk  capabilities.  IVTx, PPS and Vision
also employ their own sales and marketing and client  service  personnel to take
advantage of individual market opportunities.

     MEMBER SERVICES. The Company believes that client satisfaction is dependent
upon member  satisfaction.  Members can call the Company  toll-free,  six days a
week, to obtain  information  about their  prescription  drug plan.  The Company
employs  member  service  representatives  who are  trained to respond to member
inquiries.

     PROVIDER  RELATIONS.  The Company's Provider Relations group is responsible
for contracting and administering  the Company's  networks of over 50,000 retail
pharmacies.  To participate in the Company's pharmacy networks,  pharmacists are
periodically  required to represent to the Company that their  applicable  state
licensing  requirements are being maintained and that they are in good standing.
Pharmacies  can contact the Company's  pharmacy help desks  toll-free,  24 hours
every day, for information and assistance in filling  prescriptions for members.
The  Company's  Provider  Relations  group  also  periodically  audits  selected
pharmacies in the pharmacy  networks to determine  compliance  with the terms of
the contract with the Company or its clients.

     CLINICAL  SUPPORT.  The Company's  Health  Management  Services  Department
employs clinical pharmacists, data analysts and outcomes researchers who provide
technical support for the Company's  advanced PBM services.  These staff members
assist in providing  high level  clinical  pharmacy  services  such as formulary
development,  drug information programs, clinical interventions with physicians,
development of drug therapy guidelines and the evaluation of drugs for inclusion
in  clinically  sound  therapeutic  switching  programs.  The Health  Management
Services Department also analyzes and prepares reports on clinical pharmacy data
for  clients   and   conducts   specific   data   analyses   to   evaluate   the
cost-effectiveness of certain drug therapies.

     MANAGEMENT   INFORMATION  SYSTEMS.  The  Company's  Management  Information
Systems department  supports the Company's pharmacy claims processing system and
other  management  information  systems  which are  essential  to the  Company's
operations.  Because  uninterrupted  point-of-sale  electronic  pharmacy  claims
processing is a significant  operational requirement for the Company, the claims
processing  systems located in the Company's Missouri and Arizona facilities are
designed to be redundant,  enabling the Company to do  substantially  all claims
processing  in one facility if the other  facility is unable to process  claims.
The  Company  has  substantial  capacity  for  growth in its  claims  processing
facilities.

     The Company's operations rely heavily on information systems technology. In
1995, the Company began addressing the "Year 2000" issue which, in short, refers
to the inability of certain computer systems to recognize  calendar dates beyond
December 31,  1999.  This arises as a result of systems  having been  programmed
with two-digits  rather than  four-digits to define the applicable year in order
to conserve  computer  storage space,  reduce the complexity of calculations and
produce  better  performance.  The  two-digit  system  may  cause  computers  to
interpret the years "00" as "1900" rather than as "2000", which may cause system
failures  or  produce  incorrect   results  when  dealing  with   date-sensitive
information beyond the year 1999.

     The Company has performed a self-assessment  and has developed a compliance
plan that addresses (i) internally developed application  software,  (ii) vendor
developed  application software,  (iii) operating system software,  (iv) utility
software,  (v) vendor/trading  partner-supplied  files, (vi) externally provided
data or  transactions,  and (vii)  adherence to applicable  industry  standards.
Progress  in  each  area  is  monitored   and   management   reports  are  given
periodically.  In  addition,  all new  internally  developed  software  is being
created to be Year 2000 compliant.  The Company  believes that, with appropriate
modifications  to  existing  computer  systems,  updates by vendors  and trading
partners, and conversion to new software in the ordinary course of its business,
the Year 2000 problem  will not pose  significant  operational  problems for the
Company.  However,  if such conversions are not completed in a proper and timely
manner by all  affected  parties,  the Year 2000  issue  could  have a  material
adverse impact on the business and  operations of the Company,  and there can be
no  assurance  that the  Company's  efforts,  or those of  vendors  and  trading
partners,  to address the Year 2000 issue will be successful.  See Item 7 herein
for additional information concerning the Year 2000 issue.

COMPETITION

     The Company  believes that the primary  competitive  factors in each of its
businesses are price, quality of service and breadth of available services.  The
Company  also  believes  that its  larger  PBM  competitors  offer  all core and
advanced PBM services,  and that most of the Company's smaller competitors offer
only core PBM services and some, but not all, advanced PBM services. The Company
considers its principal  competitive  advantages  to be  independence  from drug
manufacturer  ownership,  a strong managed care customer base which supports the
development of advanced PBM services,  and commitment to providing  flexible and
distinctive service to its customers. This service commitment led to the Company
being ranked first in overall customer  satisfaction for the second  consecutive
year, and receiving the highest average overall ranking, in the Pharmacy Benefit
Management  Institute  Customer  Satisfaction  Survey,  which is an  independent
survey of employers and managed care organizations.

     There are a large  number of  companies  offering  PBM services in the U.S.
Most of these companies are smaller than the Company and offer their services on
a local or regional basis. As a full service, national pharmacy benefit manager,
the Company competes with a number of large, national companies, including Merck
Medco Managed  Care,  Inc. (a  subsidiary  of Merck & Co.,  Inc.),  PCS, Inc. (a
subsidiary of Eli Lilly & Company), Diversified Pharmaceutical Services, Inc. (a
subsidiary of SmithKline Beecham), and Caremark International Inc. (a subsidiary
of MedPartners,  Inc.), as well as numerous insurance and Blue Cross/Blue Shield
plans,   certain   HMOs  and  retail  drug  chains  which  have  their  own  PBM
capabilities. Many of these other companies have greater financial and marketing
resources than the Company.

     Consolidation is a critical factor in the pharmaceutical industry generally
and  in  the  pharmacy  benefit  management  segment  in  particular.   Vertical
integration   has  resulted  in  significant   movements  in  market  share,  as
competitors that are owned by manufacturers may have pricing advantages that are
unavailable  to the Company and other  independent  PBMs.  However,  the Company
believes  that  independence  from drug  manufacturer  ownership is important to
clients in certain market segments.

     The  Company  announced  on  February  20,  1998,  that it had  executed  a
definitive  agreement  to purchase  ValueRx,  the PBM  business of  Columbia/HCA
Healthcare corporation,  for $445 million. When completed,  the Company believes
that  it will be the  largest  PBM  that  is  independent  of drug  manufacturer
ownership.  As more particularly  discussed herein in Item 7 consummation of the
transaction is subject to customary closing conditions and regulatory  approval,
but is expected to occur during the second quarter of 1998.

     The Company's disease management product offerings compete with those being
offered by  pharmaceutical  manufacturers,  other PBMs and  specialized  disease
management  companies.  The  Company's  informed  decision  counseling  service,
Express Health LineSM,  competes with several national  vendors,  such as Access
Health,  Inc.,  CareWise,  Inc.,  Optum and  National  Health  Enhancement.  The
Company's medical information management subsidiary,  PPS, competes with various
information   service   providers  and  software  vendors  who  offer  competing
information and software  products.  With respect to its vision care plans,  the
Company   competes   primarily   against   Vision  Service  Plan,  a  California
not-for-profit  corporation,  and  certain  other  plans  that  provide  optical
services  on a  discounted  basis  and a large  number  of  regional  and  local
providers.  With respect to infusion therapy services, the Company competes with
a number of large national companies as well as with local providers.

GOVERNMENT REGULATION

     Various  aspects of the  Company's  businesses  are governed by federal and
state laws and  regulations.  Since  sanctions may be imposed for  violations of
these laws, compliance is a significant operational requirement for the Company.
The Company  believes  that it is in  substantial  compliance  with all existing
legal requirements material to the operation of its businesses.

     PHARMACY  BENEFIT  MANAGEMENT  REGULATION  GENERALLY.  Certain  federal and
related state laws and regulations affect or may affect aspects of the Company's
PBM business. Among these are the following:

     FDA REGULATION. The U.S. Food and Drug Administration ("FDA") generally has
authority to regulate drug promotional materials that are disseminated "by or on
behalf of" a drug  manufacturer.  In  October,  1995,  the FDA held  hearings to
determine  whether and to what extent the activities of PBM companies  should be
subject to FDA  regulation.  At this hearing,  FDA officials  expressed  concern
about the  efforts  of PBMs that are  owned by drug  manufacturers  to engage in
therapeutic  switching  programs and about the  criteria  used by such PBMs that
govern the inclusion and exclusion of particular  drugs in formularies.  Various
parties,  including the Company, submitted written comments to the FDA regarding
the basis for FDA regulation of PBM  activities.  It was the Company's  position
that,  while the FDA may have  jurisdiction  to regulate  PBMs that are owned by
drug  manufacturers,  the  prescription  drug  benefit  programs  developed  and
implemented by independent  PBMs do not constitute the distribution of materials
that promote particular drugs "on behalf of" any  pharmaceutical  manufacturers,
and therefore, these programs are not subject to FDA regulation. The FDA did not
publish any proposed rules on the regulation of PBMs at that time.

     In January,  1998, the FDA issued a Notice and Draft Guidance regarding its
intent to regulate  certain drug promotion and switching  activities of pharmacy
benefit  managers  that  are  controlled,   directly  or  indirectly,   by  drug
manufacturers.  The  position  taken by the FDA in the  Draft  Guidance  is that
promotional  materials  used  by an  independent  PBM  may  be  subject  to  FDA
regulation  depending  upon  the  circumstances,  including  the  nature  of the
relationship  between  the PBM  and  the  manufacturer.  Comments  to the  Draft
Guidance are due April 6, 1998 There can be no  assurance  that the FDA will not
continue  to assert  jurisdiction  over  certain  aspects of the  Company's  PBM
business,  and in such event the impact could  materially  adversely  affect the
Company's operations.

     ANTI-REMUNERATION  LAWS.  Medicare and Medicaid law prohibits,  among other
things,  an entity from paying or receiving,  subject to certain  exceptions and
"safe harbors," any  remuneration to induce the referral of Medicare or Medicaid
beneficiaries  or the  purchase (or the  arranging  for or  recommending  of the
purchase)  of items or services  for which  payment may be made under  Medicare,
Medicaid, or other  federally-funded  state healthcare programs.  Several states
also have similar  laws which are not limited to services for which  Medicare or
Medicaid  payment  may be made.  State  laws  vary and  have  been  infrequently
interpreted  by courts or regulatory  agencies.  Sanctions  for violating  these
federal and state anti-remuneration laws may include imprisonment,  criminal and
civil  fines,  and  exclusion  from  participation  in the Medicare and Medicaid
programs.

     The federal statute has been interpreted  broadly by courts,  the Office of
Inspector  General  (OIG)  within the  Department  of Health and Human  Services
(HHS), and administrative  bodies. Because of the federal statute's broad scope,
federal  regulations  establish  certain  "safe  harbors" from  liability.  Safe
harbors exist for certain  properly  reported  discounts  received from vendors,
certain  investment  interests,  and certain properly disclosed payments made by
vendors to group purchasing organizations. HHS has recently announced a proposed
safe harbor that would protect certain discount and payment arrangements between
PBMs and HMO risk contractors  serving Medicaid and Medicare members. An interim
final rule in  anticipated  in Spring,  1998,  on this  matter.  Nonetheless,  a
practice  that does not fall within a safe harbor is not  necessarily  unlawful,
but may be subject to scrutiny and  challenge.  In the absence of an  applicable
exception or safe harbor,  a violation of the statute may occur even if only one
purpose of a payment  arrangement is to induce  patient  referrals or purchases.
Among the practices that have been identified by the OIG as potentially improper
under the statute are certain  "product  conversion  programs" in which benefits
are given by drug  manufacturers  to  pharmacists  or physicians  for changing a
prescription  (or  recommending  or  requesting  such a change) from one drug to
another. Such laws have been cited as a partial basis, along with state consumer
protection laws discussed below, for investigations and multi-state  settlements
relating  to  financial  incentives  provided  by drug  manufacturers  to retail
pharmacies in connection with such programs.

     To the  Company's  knowledge,  these  anti-remuneration  laws have not been
applied to prohibit  PBMs from  receiving  amounts  from drug  manufacturers  in
connection  with  drug  purchasing  and  formulary   management   programs,   to
therapeutic  substitution  programs  conducted by  independent  PBMs,  or to the
contractual  relationships  such as those the  Company  has with  certain of its
customers.  The Company  believes that it is in substantial  compliance with the
legal  requirements  imposed  by such  laws  and  regulations,  and the  Company
believes that there are material  differences  between  drug-switching  programs
that have been  challenged  under  these  laws and the  programs  offered by the
Company to its  customers.  However,  there can be no assurance that the Company
will not be subject to scrutiny or challenge under such laws or regulations,  or
that any such  challenge  would  not have a  material  adverse  effect  upon the
Company.

     ERISA  REGULATION.  The  Employee  Retirement  Income  Security Act of 1974
("ERISA")  regulates  certain  aspects of employee  pension  and health  benefit
plans,  including  self-funded corporate health plans with which the Company has
agreements to provide PBM services. The Company believes that the conduct of its
business is not subject to the fiduciary  obligations of ERISA, but there can be
no  assurance  that the U.S.  Department  of  Labor,  which is the  agency  that
enforces ERISA, would not assert that the fiduciary  obligations  imposed by the
statute apply to certain aspects of the Company's operations.

     PROPOSED CHANGES IN CANADIAN  HEALTHCARE  SYSTEM. In Canada, the provincial
health plans  provide  universal  coverage for basic  healthcare  services,  but
prescription  drug coverage under the government  plans is provided only for the
elderly and the indigent. A proposal was made by a Federal government healthcare
task force to include  coverage  for  prescription  drugs  under the  provincial
health  insurance plans,  which report was endorsed by the Federal  government's
Health  Minister.  This report was advisory in nature,  and not binding upon the
Federal  or  provincial  governments.  The  Company is unable to  determine  the
likelihood of adoption of the proposal at this time.

     Numerous  state laws and  regulations  also affect aspects of the Company's
PBM business. Among these are the following:

     COMPREHENSIVE  PBM  REGULATION.  Although  no state has passed  legislation
regulating PBM activities in a comprehensive  manner,  such legislation has been
introduced  on two  occasions in  California.  Such  legislation,  if enacted in
California or another state in which the Company has a significant concentration
of business, could adversely impact the Company's operations.

     CONSUMER  PROTECTION  LAWS. Most states have consumer  protection laws that
have been the basis for investigations and multi-state  settlements  relating to
financial  incentives  provided by drug  manufacturers  to retail  pharmacies in
connection with drug switching programs.  In addition,  pursuant to a settlement
agreement  entered into with seventeen  states on October 25, 1995,  Merck Medco
Managed Care, Inc. ("Medco"), the PBM subsidiary of pharmaceutical  manufacturer
Merck & Co.,  agreed to have  pharmacists  affiliated  with Medco  mail  service
pharmacies  disclose to  physicians  and  patients the  financial  relationships
between  Merck,  Medco,  and the mail  service  pharmacy  when such  pharmacists
contact  physicians  seeking to change a prescription  from one drug to another.
The Company believes that its contractual  relationships with drug manufacturers
and  retail  pharmacies  do  not  include  the  features  that  were  viewed  by
enforcement authorities as problematic in these settlement agreements.  However,
no  assurance  can be given that the Company  will not be subject to scrutiny or
challenge under one or more of these laws.

     NETWORK  ACCESS  LEGISLATION.  A  majority  of states now have some form of
legislation  affecting  the ability of the Company to limit access to a pharmacy
provider  network or from  removing  network  providers.  Such  legislation  may
require the Company or its client to admit any retail  pharmacy  willing to meet
the  plan's  price  and other  terms for  network  participation  ("any  willing
provider" legislation); or may provide that a provider may not be removed from a
network   except  in  compliance   with  certain   procedures   ("due   process"
legislation).  The Company has not been  materially  affected by these  statutes
because it maintains a large network of over 50,000 retail  pharmacies  and will
admit any licensed  pharmacy that meets the Company's  credentialling  criteria,
involving  such  matters  as  adequate  insurance  coverage,  minimum  hours  of
operation,  and the  absence  of  disciplinary  actions  by the  relevant  state
agencies.

     LEGISLATION  IMPOSING  PLAN DESIGN  RESTRICTIONS.  Some states have enacted
legislation   that  prohibits  the  plan  sponsor  from   implementing   certain
restrictive  design  features,  and many states have  introduced  legislation to
regulate various aspects of managed care plans, including provisions relating to
the pharmacy benefit. For example,  some states provide that members of the plan
may not be required to use network providers,  but must instead be provided with
benefits even if they choose to use non-network  providers  ("freedom of choice"
legislation).  Other states have enacted legislation  purporting to prohibit the
health plan from offering  members  financial  incentives  for use of mail order
pharmacies.  Legislation  has been  introduced  in some  states to  prohibit  or
restrict  therapeutic  substitution,  or to require coverage of all FDA approved
drugs.  Other states mandate  coverage of certain  benefits or conditions.  Such
legislation does not generally apply to the Company, but it may apply to certain
of the Company's customers (HMOs and health insurers).  If such legislation were
to become  widespread  and broad in scope,  it could have the effect of limiting
the economic benefits achievable through pharmacy benefit management.

     LICENSURE LAWS.  Many states have licensure or registration  laws governing
certain types of ancillary healthcare  organizations,  including PPOs, TPAs, and
companies  that provide  utilization  review  services.  The scope of these laws
differs  significantly  from state to state, and the application of such laws to
the activities of pharmacy  benefit  managers often is unclear.  The Company has
registered  under such laws in those states in which the Company has  concluded,
after discussion with the appropriate  state agency,  that such  registration is
required.

     LEGISLATION  AFFECTING  DRUG PRICES.  Some states have adopted  legislation
providing that a pharmacy  participating in the state Medicaid program must give
the state the best price that the  pharmacy  makes  available to any third party
plan ("most favored nation" legislation).  Such legislation may adversely affect
the  Company's  ability  to  negotiate  discounts  in the  future  from  network
pharmacies.  Other  states have enacted  "unitary  pricing"  legislation,  which
mandates that all wholesale purchasers of drugs within the state be given access
to the same discounts and incentives.  Such  legislation has been introduced but
not yet  enacted in Missouri  and  Arizona,  where the  Company's  mail  service
pharmacies  are located.  Such  legislation,  if enacted in either state,  could
adversely affect the Company's ability to negotiate discounts on its purchase of
prescription drugs to be dispensed by its mail service pharmacies.

     REGULATION OF FINANCIAL RISK PLANS. Fee-for-service prescription drug plans
are generally not subject to financial regulation by the states. However, if the
PBM  offers to  provide  prescription  drug  coverage  on a  capitated  basis or
otherwise  accepts  material  financial  risk in providing the benefit,  laws in
various  states may regulate  the plan.  Such laws may require that the party at
risk establish reserves or otherwise demonstrate financial responsibility.  Laws
that may apply in such cases include insurance laws, HMO laws or limited prepaid
health  service plan laws.  In those cases in which the Company has contracts in
which it is  materially  at risk to provide the  pharmacy  benefit,  the Company
believes that it has complied with all applicable laws.

     Many of these  state  laws may be  preempted  in whole or in part by ERISA,
which provides for comprehensive  Federal  regulation of employee benefit plans.
However,  the  scope  of  ERISA  preemption  is  uncertain  and  is  subject  to
conflicting  court rulings,  and in any event the Company  provides  services to
certain customers,  such as governmental  entities,  that are not subject to the
preemption  provisions of ERISA.  Other state laws may be invalid in whole or in
part as an unconstitutional  attempt by a state to regulate interstate commerce,
but the  outcome  of  challenges  to  these  laws on this  basis  is  uncertain.
Accordingly,  compliance  with  state  laws  and  regulations  is a  significant
operational requirement for the Company.

     MAIL PHARMACY REGULATION. The Company's mail service pharmacies are located
in Missouri and Arizona and the Company is licensed to do business as a pharmacy
in  each  such  state.  Many of the  states  into  which  the  Company  delivers
pharmaceuticals have laws and regulations that require out-of-state mail service
pharmacies to register with, or be licensed by, the board of pharmacy or similar
regulatory  body in the state.  These states  generally  permit the mail service
pharmacy to follow the laws of the state within which the mail service  pharmacy
is  located,  although  one  state  also  requires  that  the  Company  employ a
pharmacist  licensed in that state. The Company has registered in every state in
which, to the Company's knowledge, such registration is required.

     One state has a statute that purports to prohibit  residents from obtaining
prescription  drugs by mail if the mail order business of the company dispensing
the drugs  represents  more than a specified  percentage of the company's  total
volume of pharmacy business.  The statute is ambiguous in certain respects,  but
the  Company  does not  believe  its mail order  volume  exceeds  the  threshold
percentage.  The Company is licensed as a pharmacy in that state. No enforcement
action  has been  taken  under  the  statute  against  the  Company,  and to the
Company's knowledge,  no such enforcement action is contemplated.  Approximately
2.6% of the Company's  revenues come from mail  delivery of  prescription  drugs
into that state.  If an  enforcement  action  against the Company were commenced
under  that  statute,  the  Company  would  consider  all of  its  alternatives,
including challenging the validity of the statute.

     Other   statutes  and   regulations   affect  the  Company's  mail  service
operations.  Federal  statutes and regulations  govern the labeling,  packaging,
advertising  and  adulteration  of  prescription  drugs  and the  dispensing  of
controlled substances.  The Federal Trade Commission requires mail order sellers
of goods  generally  to engage in truthful  advertising,  to stock a  reasonable
supply of the product to be sold, to fill mail orders within thirty days, and to
provide  customers  with  refunds when  appropriate.  The United  States  Postal
Service has  statutory  authority  to  restrict  the  transmission  of drugs and
medicines  through the mail to a degree that could have an adverse effect on the
Company's mail service  operations.  The U.S.  Postal Service has exercised such
statutory  authority  only with respect to  controlled  substances.  Alternative
means of delivery are available to the Company.

     REGULATION OF INFORMED DECISION COUNSELING AND DISEASE MANAGEMENT SERVICES.
The Company's  healthcare  decision  support  counseling and disease  management
programs are affected by many of the same types of state laws and regulations as
the Company's other activities. In addition, all states regulate the practice of
medicine and the practice of nursing.  The Company does not believe its informed
decision  counseling  or disease  management  activities  constitute  either the
practice  of  medicine or the  practice  of  nursing.  However,  there can be no
assurance  that a  regulatory  agency  in one or more  states  may not  assert a
contrary  position,  and there is no controlling legal precedent for services of
this kind.

     REGULATION  OF MANAGED  VISION  CARE.  The  Company's  managed  vision care
program is subject  to many of the same or  similar  state laws and  regulations
affecting the Company's PBM business. The Company offers its vision care program
on a fee-for-service  and capitated basis. The Company has determined that it is
required to obtain an HMO or equivalent license to offer its vision care program
on a capitated  basis in several  states.  Unless it obtains such licenses,  the
Company  will offer its vision care  program to  customers  based in such states
only on a fee-for-service basis.

     REGULATION OF INFUSION  THERAPY  SERVICES.  The Company's  infusion therapy
services  business  is  subject  to many of the same or  similar  state laws and
regulations  affecting the Company's pharmacy management business.  In addition,
some states require that providers of infusion therapy services be licensed. The
Company  is  licensed  as a home  health  agency  and  pharmacy  in Texas,  as a
residential  service  agency and pharmacy in Maryland,  and as a pharmacy in New
Jersey,  Missouri,  Arizona and Pennsylvania.  The Company is also licensed as a
non-resident  pharmacy in various  states.  The Company  believes  that it is in
substantial compliance with such licensing requirements.

         The Joint Commission on Accreditation of Healthcare Organizations
("JCAHO"), a non-profit, private organization, has established written standards
for healthcare organizations and home care services, including standards for
services provided by home infusion therapy companies. All of the Company's
infusion therapy facilities have received JCAHO accreditation, which allows the
Company to market infusion therapy services to Medicare and Medicaid programs.
If the Company expands its home infusion therapy services to other states or to
Medicare or Medicaid programs, it may be required to comply with other
applicable laws and regulations.

     PRIVACY AND CONFIDENTIALITY  LEGISLATION.  Most of the Company's activities
involve the receipt or use by the Company of confidential,  medical  information
concerning  individual  members,  including  the  transfer  of the  confidential
information to the member's  health benefit plan. In addition,  the Company uses
aggregated (anonymized) data for research and analysis purposes. Legislation has
been proposed at the federal level and in several states to restrict the use and
disclosure of confidential medical information. To date, no such legislation has
been  enacted  that  adversely  impacts  the  Company's  ability to provide  its
services,  but there can be no assurance that federal or state  governments will
not enact legislation,  impose restrictions or adopt interpretations of existing
laws that could have a material adverse effect on the Company's operations.

     FUTURE  REGULATION.  The  Company  is unable  to  predict  accurately  what
additional Federal or state legislation or regulatory initiatives may be enacted
in the future  relating  to the  businesses  of the  Company  or the  healthcare
industry in general,  or what effect any such  legislation or regulations  might
have on the Company. There can be no assurance that federal or state governments
will not impose  additional  restrictions or adopt  interpretations  of existing
laws that  could have a  material  adverse  effect  the  Company's  business  or
financial position.

SERVICE MARKS AND TRADEMARKS

     The Company and its subsidiaries have registered the service marks "Express
Scripts",   "PERx",   "ExpressComp",    "ExpressReview",   "IVTx",   "PERxCare",
"PERxComp",  "RxWizard"  and "PTE" with the United  States  Patent and Trademark
Office. The Company's rights to these marks will continue so long as the Company
complies with the usage, renewal filing and other legal requirements relating to
the renewal of service  marks.  The  Company is in the  process of applying  for
registration  of several other  trademarks and service marks.  If the Company is
unable to obtain any additional registrations,  the Company believes there would
be no material adverse effect on the Company.

INSURANCE

     The  dispensing of  pharmaceutical  products by the Company's  mail service
pharmacies,  the services  rendered in  connection  with the  Company's  disease
management and informed decision counseling  services,  the fabrication and sale
of eyewear by the Company,  and the products and services provided in connection
with the Company's  infusion therapy programs  (including the associated nursing
services),  may subject the Company to litigation and liability for damages. The
Company  believes  that its  insurance  protection  is adequate  for its present
business operations, but there can be no assurance that the Company will be able
to maintain its professional  and general  liability  insurance  coverage in the
future or that such insurance  coverage will be available on acceptable terms or
adequate to cover any or all potential product or professional liability claims.
A successful product or professional  liability claim in excess of the Company's
insurance coverage could have a material adverse effect upon the Company.

EMPLOYEES

     As of March 1, 1998, the Company and its  subsidiaries  employed a total of
1,519 employees in the U.S. and 51 employees in Canada.

EXECUTIVE OFFICERS OF THE REGISTRANT

     Pursuant to General Instruction G(3) of the Annual Report on Form 10-K, the
information  regarding executive officers of the Company required by Item 401 of
Regulation S-K is hereby included in Part I of this report.

     The  executive  officers of the Company and their ages as of March 1, 1998,
are as follows:

         NAME             AGE               POSITION
Howard L. Waltman         65    Chairman of the Board
Barrett A. Toan           50    President, Chief Executive
                                Officer and Director
Stuart L. Bascomb         56    Executive Vice President
Thomas M. Boudreau        46    Senior Vice President of
                                Administration, General Counsel
                                and Secretary
Robert W. (Joe) Davis     51    Senior Vice President and Chief
                                Information Systems Officer
Linda L. Logsdon          50    Senior Vice President of Health
                                Management Services
David A. Lowenberg        48    Senior Vice President and
                                Director of Site Operations
George Paz                42    Senior Vice President and Chief
                                Financial Officer
Kurt D. Blumenthal        53    Vice President of Finance
Joseph W. Plum            50    Vice President and Chief
                                Accounting Officer

     Mr. Waltman was elected Chairman of the Board of the Company in March 1992.
Mr.  Waltman has been a director of the Company since its inception in September
1986.  From 1983 until September 1992, Mr. Waltman was Chairman of the Board and
Chief  Executive  Officer of Sanus Corp.  Health  Systems,  now known as NYLCare
Health  Plans,  Inc.,  and a wholly  owned  subsidiary  of New York  Life.  From
September  1992 to December 31, 1995,  Mr. Waltman served as the Chairman of the
Board of Sanus/NYLCare.

     Mr. Toan was elected  Chief  Executive  Officer in March 1992 and President
and a director in October 1990.  Mr. Toan has been an executive  employee of the
Company since May 1989.

     Mr.  Bascomb was elected  Executive  Vice President of the Company in March
1989, and also served as Chief  Financial  Officer and Treasurer from March 1992
until May 1996.

     Mr.  Boudreau  was  elected  Senior  Vice  President,  General  Counsel and
Secretary of the Company in October  1994.  He has served as General  Counsel of
the Company since June 1994.  From September 1984 until June 1994, Mr.  Boudreau
was a partner in the St. Louis law firm of Husch & Eppenberger.

     Mr. Davis was elected Senior Vice President and Chief  Information  Systems
Officer of the  Company in  September  1997.  Mr.  Davis  served as  Director of
Technical  Services and Computer  Operations of the Company from July 1993 until
July 1995, and as Vice President and General Manager of St. Louis  Operations of
the Company from July 1995 until  September  1997. From March 1992 until joining
the  Company,  Mr.  Davis  served  as Vice  President  and  General  Manager  of
Systemhouse, LTD, an international systems integration firm.

     Ms. Logsdon was elected Senior Vice President of Health Management Services
in May, 1997, and served as Vice President of Demand and Disease Management from
November  1996 until that time.  Prior to joining the Company in November  1996,
Ms. Logsdon served as Vice President of Corporate  Services and Chief  Operating
Officer  of  United  HealthCare's  Midwest  Companies-GenCare/Physicians  Health
Plan/MetraHealth,  a  St.  Louis-based  health  maintenance  organization,  from
February 1995 to October 1996, and as Deputy Director/Vice  President of GenCare
Health Systems,  Inc., also a St. Louis-based  health maintenance  organization,
from June 1992 to February 1995.

     Mr.  Lowenberg  was elected  Senior  Vice  President  and  Director of Site
Operations of the Company in October,  1994 and Vice President of the Company in
November  1993.  Mr.  Lowenberg  also  served as  General  Manager  of the Tempe
facility from March 1993 until January 1995. From August 1992 to March 1993, Mr.
Lowenberg was President of HealthCare  Development  Consulting,  which  provided
managed care organization and financial  analysis services to private healthcare
organizations  and  government  healthcare  agencies.  From  1985 to  1992,  Mr.
Lowenberg  was Deputy  Director  of the  Arizona  Health  Care Cost  Containment
System,  the state  agency  responsible  for ensuring  quality  service and cost
containment for Medicaid recipients.

     Mr. Paz joined the Company and was elected  Senior Vice President and Chief
Financial  Officer in January 1998. Prior to joining the Company,  Mr. Paz was a
partner  in the  Chicago  office  of  Coopers & Lybrand  from  December  1995 to
December  1997,  and served as  Executive  Vice  President  and Chief  Financial
Officer of Life Partners  Group,  Inc., a life insurance  company,  from October
1993 until  December  1995.  Mr. Paz was also a partner of Coopers & Lybrand for
the period of February 1988 to October 1993.

     Mr.  Blumenthal  was elected  Vice  President  of Finance in May 1995,  and
served  as Acting  Chief  Financial  Officer  of the  Company  from July 1996 to
January 1998.  From August 1993 to February 1995, Mr.  Blumenthal  served as the
Chief Financial  Officer of President  Baking Co. From November 1981 to December
1992, Mr. Blumenthal held several positions at Wetterau,  Inc., including Senior
Vice President and Chief Financial Officer from and after March 1989.

     Mr. Plum was elected Vice President in October 1994 and has served as Chief
Accounting Officer since March 1992 and Corporate Controller since March 1989.

ITEM 2 - PROPERTIES

     The Company operates its U.S. PBM business out of leased facilities located
in Maryland Heights,  Missouri,  and Tempe,  Arizona. In addition,  the Missouri
facility  houses the  Company's  corporate  offices.  The  Canadian PBM business
operates  out  of  leased  facilities  in  Mississaugua,  Ontario,  Canada.  The
Company's  Health Line division and its PPS  subsidiary are also operated out of
the Company's  Missouri site. The Company's vision care business operates out of
leased  facilities  located in Earth City,  Missouri,  from which it distributes
contact  lenses,  grinds and edges lenses and assembles  eyeglasses.  The leased
facilities  supporting the infusion  therapy  operations are located in Maryland
Heights,  Missouri,  Dallas, Texas; Houston, Texas; Columbia,  Maryland;  Tempe,
Arizona; Northvale, New Jersey and West Chester, Pennsylvania.  IVTx's corporate
offices are located at the Company's Maryland Heights, Missouri site.

     The Company believes its facilities have been generally well maintained and
are in good operating condition.  The Company is currently evaluating its future
requirements for additional space.

     The Company owns computer  systems for both the Missouri and Arizona sites.
The Company's software for DUR and other products has been developed  internally
by the Company or purchased under  perpetual,  nonexclusive  license  agreements
with third parties.  The Company's computer systems at each site are extensively
integrated  and share  common files  through  local and wide area  networks.  An
uninterruptable   power  supply  and  diesel   generator  allows  the  Company's
computers,  telephone  systems  and mail  pharmacy  at each site to  continue to
function  during a power  outage.  To protect  against loss of data and extended
downtime,  the Company stores  software and redundant  files at both on-site and
off-site  facilities on a regular basis and has  contingency  operation plans in
place.

ITEM 3 - LEGAL PROCEEDINGS

     In the  ordinary  course of  business,  there  have  arisen  various  legal
proceedings,  investigations  or claims  pending  against  the  Company  and its
subsidiaries.  The effect of these  actions on future  financial  results is not
subject to reasonable  estimation because considerable  uncertainty exists about
the  outcomes.   Nevertheless,  in  the  opinion  of  management,  the  ultimate
liabilities  resulting  from any such  lawsuits,  investigations  or claims  now
pending will not materially affect the consolidated financial position,  results
of operations or cash flows of the Company.

    Over 100 separate  lawsuits  have been filed by retail  pharmacies  against
drug manufacturers and certain pharmacy benefit managers  challenging brand drug
pricing  practices  under various state and federal  antitrust  laws.  The suits
allege,  among other things,  that the manufacturers  have offered,  and certain
pharmacy benefit managers have knowingly accepted, discriminatory discounts that
violate the Robinson-Patman  Act. The plaintiffs have also filed claims against
the drug manufacturers and certain drug wholesalers, alleging price fixing of
pharmaceutical drugs in violation of Section 1 of the Sherman Act.  Some of 
these claims are in the form of a nationwide class action, which will commence
trial in September 1998.  Other plaintiffs have opted out of the class and will
try their claims separately.  Some of the drug manufacturers have settled both
the price fixing and the Robinson Patman claims.  These settlements provide that
the manufacturers will not refuse to pay retrospective discounts to retail 
pharmacies based on their status as such. 

     The Company is not a party to any of these proceedings.  However,  if these
discounts and rebates are determined to have violated the  Robinson-Patman  Act,
then the availability to the Company of certain discounts, rebates and fees that
it  presently  receives  could be adversely  affected.  No date has been set for
trial of the Robinson-Patman claims, and the Company can give no assurance as to
the ultimate outcome.

ITEM 4 - SUBMISSION OF MATTERS TO A VOTE OF SECURITY HOLDERS

     No matters were  submitted to a vote of security  holders during the fourth
quarter of 1997.



                                     PART II


ITEM 5 - MARKET FOR REGISTRANT'S COMMON EQUITY AND RELATED STOCKHOLDER MATTERS

  MARKET PRICE OF AND DIVIDENDS ON THE REGISTRANT'S COMMON EQUITY AND RELATED
                              STOCKHOLDER MATTERS

     MARKET  INFORMATION.  The Company's Class A Common Stock has been traded on
the Nasdaq National Market  ("Nasdaq") tier of The Nasdaq Stock Market under the
symbol "ESRX" since June 9, 1992. Prior to that time, there was no public market
for the  Company's  Common  Stock.  The high and low prices,  as reported by the
Nasdaq, are set forth below for the periods indicated.

                               Fiscal Year 1997            Fiscal Year 1996
   Class A Common Stock        High         Low           High           Low
     First Quarter             $ 38.25      $ 31.25       $ 58.00        $ 44.50
     Second Quarter              49.00        32.75         52.00          38.50
     Third Quarter               54.50        41.50         45.00          26.50
     Fourth Quarter              64.75        50.625        39.25          26.50

     The  Company's  Class B Common  Stock  has no  established  public  trading
market, but those shares will automatically convert to Class A Common Stock on a
share for share basis upon  transfer  thereof to any entity  other than New York
Life Insurance Company or one of its affiliates.

     HOLDERS.  As of March 6, 1997, there were 202 stockholders of record of the
Company's  Class A Common  Stock,  and 1 holder  of record of the Class B Common
Stock.  The  Company   estimates  there  are   approximately   8,500  beneficial
stockholders of the Class A Common Stock.

     DIVIDENDS.  The Board of Directors  has not declared any cash  dividends on
the  Company's  common  stock since the initial  public  offering.  The Board of
Directors  does not  currently  intend  to  declare  any cash  dividends  in the
foreseeable future.

     RECENT SALES OF UNREGISTERED SECURITIES

     EMPLOYEE  STOCK OPTIONS.  During 1997,  the Company issued 141,500  options
(the "Options") to acquire an equivalent  number of shares of its Class A Common
Stock (the  "Common  Stock") to certain  of its key  employees  pursuant  to the
Company's  Amended  and  Restated  1992 Stock  Option  Plan and its  Amended and
Restated 1994 Stock Option Plan  (collectively,  the "Plans").  The Compensation
Committee of the Company's Board of Directors (the "Committee")  administers the
Plans.  As a condition to receipt of the Options,  the  Committee  required that
each recipient  execute and deliver an agreement  prohibiting  the employee from
competing  with the  company  or  soliciting  the  employment  of the  Company's
employees  for  specified  periods  after most  terminations  of the  employee's
employment  with the Company.  The exercise  prices of the Options were equal to
the market values on their respective dates of grant, as described in the Plans.
The Committee has  discretion to determine the vesting  schedule for each Option
grant. Generally, the Committee has made grants that become exercisable in equal
amounts over five years,  and in most cases the employee must be employed by the
Company at the time of vesting to exercise their  Options.  Reference is made to
the text of the  Plans,  which  are  filed  with the  Commission,  for  detailed
information  on the  terms  thereof.  The  Option  issuances  were  exempt  from
registration  under the Securities Act of 1933, as amended,  pursuant to Section
4(2)  thereof and Rule 506 of  Regulation  D  thereunder,  based on, among other
factors,  the  limited  number of the Option  acquirers,  the type and amount of
information  available to the Option  acquirers,  and the absence of any general
solicitation or advertising in connection with the issuance.



ITEM 6 - SELECTED FINANCIAL DATA

SELECTED FINANCIAL AND OPERATING DATA


(IN THOUSANDS EXCEPT PER SHARE,                        Year Ended December 31,
                                                                                                     
OPERATING AND NON-FINANCIAL DATA)                   1997            1996            1995            1994           1993
- -----------------------------------------------------------------------------------------------------------------------
STATEMENT OF OPERATIONS DATA:

Net revenues                                $  1,230,634    $    773,615    $    544,460    $    384,504   $    264,868
                                          -----------------------------------------------------------------------------
Costs and expenses:
    Cost of revenues                           1,119,167         684,882         478,283         338,151        236,398
    Selling, general and administrative           62,617          49,103          37,300          25,882         15,591
                                          -----------------------------------------------------------------------------
                                               1,181,784         733,985         515,583         364,033        251,989
                                          -----------------------------------------------------------------------------
Operating income                                  48,850          39,630          28,877          20,471         12,879
Other income, net                                  5,856           3,450             757             305            165
                                          -----------------------------------------------------------------------------
Income before income taxes                        54,706          43,080          29,634          20,776         13,044
Provision for income taxes                        21,277          16,932          11,307           8,053          4,945
                                          -----------------------------------------------------------------------------
Net income                                $       33,429    $     26,148    $     18,327    $     12,723     $    8,099
                                          =============================================================================
Basic earnings per share(1)               $         2.04    $       1.63    $       1.23    $       0.86     $     0.55
Diluted earnings per share(1)             $         2.02    $       1.60    $       1.20    $       0.84     $     0.55
- -----------------------------------------------------------------------------------------------------------------------
BALANCE SHEET DATA:
Total current assets                       $     363,968    $    263,149    $    144,415   $      93,826  $      64,230
Total assets                                     402,508         300,425         164,088         108,922         76,144
Total current liabilities                        197,906         134,890          85,762          55,744         37,467
Working capital                                  166,062         128,259          58,653          38,082         26,763
Stockholders' equity                             203,701         164,090          77,379          52,485         38,273

- -----------------------------------------------------------------------------------------------------------------------
OPERATING DATA:
Analysis of Results:
    Gross margin                                    9.1%           11.5%           12.2%           12.0%          10.8%
    Operating margin                                4.0%            5.1%            5.3%            5.3%           4.9%
    Pretax margin                                   4.4%            5.6%            5.4%            5.4%           5.0%
    Net margin                                      2.7%            3.4%            3.3%            3.3%           3.1%
    Return on assets                               11.1%           15.9%           16.8%           16.7%          17.8%
    Return on equity                               20.4%           33.8%           34.9%           33.2%          27.3%

- -----------------------------------------------------------------------------------------------------------------------
NON-FINANCIAL DATA:
Pharmacy network
    claims processed                          73,164,000      57,838,000      42,871,000      26,323,000     18,296,000
Mail pharmacy
    prescriptions filled                       3,899,000       2,770,000       2,129,000       1,594,000      1,233,000
Number of pharmacies in
    pharmacy network                              50,200          48,300          46,500          36,900         32,900
Pharmacy benefit
    covered lives                             12,600,000       9,900,000       8,100,000       5,700,000      4,200,000

- -----------------------------------------------------------------------------------------------------------------------


(1)Earnings  per share have been restated in accordance with FASB Statement
128,  "Earnings  Per  Share," to provide  basic and diluted  earnings  per share
information.



ITEM 7 - MANAGEMENT'S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS
OF OPERATIONS

OVERVIEW

     The  Company  primarily  derives  its  revenues  from the sale of  pharmacy
benefit  management  ("PBM")  services  in the  United  States and  Canada.  The
Company's  net  revenues  include   administrative   and  dispensing  fees  plus
ingredient cost of pharmaceuticals  dispensed to members of health benefit plans
sponsored by the  Company's  clients by pharmacies  participating  in one of the
networks  of  retail  pharmacies  maintained  by  the  Company  or by one of the
Company's  mail  service  pharmacies.  Where the Company  only  administers  the
contracts between its clients and their own retail pharmacy  networks,  or where
the Company dispenses  pharmaceuticals from its mail service pharmacies that are
supplied by one of the  Company's  clients,  the Company  records as net revenue
only the administrative or dispensing fees it receives from its activities.  The
Company also derives  revenue from (i) the sale of  pharmaceuticals  for and the
provision of infusion therapy services through its IVTx division ("IVTx"),  (ii)
the sale of  eyeglasses  and  contact  lenses and  related  administrative  fees
through its Express Scripts Vision Corporation  subsidiary  ("ESVC"),  (iii) the
sale of informed decision  counseling services through its Express Health LineSM
division,  and (iv) the sale of medical information  management services,  which
include provider  profiling,  disease  management  support services and outcomes
assessments,  through its Practice Patterns Science,  Inc. ("PPS") subsidiary or
Health Management Services division ("HMS").

RESULTS OF OPERATIONS

     The following  table sets forth certain  financial  data of the Company for
the periods  presented as a percentage of net revenues and the percentage change
in the dollar  amounts of such financial data for 1997 compared to 1996 and 1996
compared to 1995.



                                                        Percentage of Net Revenues                   % Increase
                                                          Year Ended December 31,               1997             1996
                                                    1997            1996           1995       Over 1996       Over 1995
                                                                                                     
                                ---------------------------------------------------------------------------------------
Net revenues:
Unrelated clients                                  83.1%           80.3%          80.2%           64.6%           42.3%
Related clients(1)                                 16.9%           19.7%          19.8%           36.6%           41.2%
                                -------------------------------------------------------
Total net revenues                                100.0%          100.0%         100.0%           59.1%           42.1%
                                -------------------------------------------------------

Costs and expenses:
    Cost of revenues                               90.9%           88.5%          87.8%           63.4%           43.2%
    Selling, general & administrative               5.1%            6.4%           6.9%           27.5%           31.6%
                                -------------------------------------------------------
                                                   96.0%           94.9%          94.7%           61.0%           42.4%
                                -------------------------------------------------------

Operating Income                                    4.0%            5.1%           5.3%           23.3%           37.2%

Other income, net                                   0.5%            0.5%           0.1%           69.7%          355.7%
                                -------------------------------------------------------
Income before income taxes                          4.5%            5.6%           5.4%           27.0%           45.4%
Provision for income taxes                          1.8%            2.2%           2.1%           25.7%           49.7%
                                -------------------------------------------------------                                       
Net income                                          2.7%            3.4%           3.3%           27.9%           42.7%
                                =======================================================


(1)Related  clients consist of NYLCare Health Plans,  Inc.  ("NYLCare") and
New  York  Life  Insurance  Company.  See  note  3  to  the  December  31,  1997
consolidated financial statements for further discussion.



YEAR ENDED DECEMBER 31, 1997, COMPARED TO 1996

     NET  REVENUES.  Net revenues  for 1997  increased  $457,019,000,  or 59.1%,
compared to 1996. Net revenues from the Company's claims processing services and
mail pharmacy  services  increased 59.5% in 1997,  compared to 1996. The primary
reason for this  increase was a  $311,195,000,  or a 60.0%  increase in revenues
from  pharmacy  claims  processed  reflecting a 26.5%  increase in the number of
claims processed,  and a 26.6% increase in average revenue per claim compared to
1996. Revenue from the Company's mail pharmacy services increased  $129,273,000,
or 58.2%, reflecting a 40.8% increase in the number of prescriptions  dispensed,
and a 12.4%  increase in the average  revenue per  prescription  dispensed.  The
increase in average  revenue per pharmacy claim processed is due to two factors:
(1) a  shift  in the  mix  of  customers  towards  utilizing  pharmacy  networks
established by the Company (for which the drug ingredient costs,  dispensing fee
and administrative fees are included as revenues), rather than networks arranged
by its clients (for which the Company records only its administrative fee as net
revenue);  and (2)  higher  drug  ingredient  costs  resulting  from  changes in
therapeutic  mix and dosage,  new drugs  introduced  into the  marketplace,  and
increased pricing. The increase in average revenue per prescription dispensed by
the mail  service  pharmacies  is  primarily  the result of: (1) the higher drug
ingredient costs  attributable to the foregoing  factors;  and (2) the fact that
two of the Company's  larger clients  switched from programs in which they would
provide drug inventory to replace drugs used by the Company to fill mail service
prescriptions  (for which the Company only  includes its  dispensing  fee as net
revenue) to the Company's  standard  program in which the Company  purchases the
inventory used to fill the prescriptions  (and therefore includes the ingredient
cost as well as the dispensing  fee in net revenue).  This switch had the effect
of  increasing  both the mail  pharmacy  services  revenue  and cost of  revenue
compared to 1996,  but the overall  effect on the Company's  reported net income
for the year was not  material.  Increases  in revenue  from the  factors  cited
herein were partially offset by lower pricing offered by the Company in response
to continued competitive pressures.

     The  increase  in the  number of claims  processed  and the  number of mail
service  pharmacy  prescriptions  dispensed  reflects  a 27.3%  increase  in the
average number of members served from  approximately  9.9 million members served
at December 31, 1996 to  approximately  12.6 million  members served at December
31, 1997.  The percentage  increase in claims  processing  revenue  continues to
exceed the percentage increase in mail service revenues, as the price difference
between  mail  pharmacy   prescriptions   and  network  pharmacy   prescriptions
decreases.  Management  expects this trend to potentially  reverse by the end of
1998 as a result of the loss of the FHP  business  as  discussed  in the  "Other
Matters"  section and as the mail service  benefit is used more  frequently by a
larger  number of members.  Of the  Company's  net revenues from PBM services in
1997,  15.7% was for  services  provided  to members of HMOs owned or managed by
NYLCare or insurance policies administered by NYLCare.

     Net revenues from the Company's other business units,  IVTx, ESVC,  Express
Health Line, PPS and HMS, increased 50.0%,  compared to 1996, as a result of the
growth in the number of members  and/or clients who receive these  services.  Of
the Company's net revenues for IVTx, ESVC and Express Health Line, 56.6% was for
services  provided to members of HMOs owned or managed by NYLCare and  insurance
policies administered by NYLCare

     COST OF REVENUES.  Cost of revenues  for 1997  increased  $434,285,000,  or
63.4%,  compared to 1996. The  percentage  increase in cost of revenues was 4.3%
greater than the  increase in revenues,  resulting in a decrease in gross profit
margins. For claims processing services,  the cost of revenue as a percentage of
net claims revenue increased by 2.7% due to both the increase in the utilization
of the Company's networks,  as opposed to those arranged by its clients,  and to
lower prices  offered in response to competitive  pressures in the  marketplace.
The mail  pharmacy  gross margin  decreased by 2.5% as a result of the switch by
certain clients away from the  replenishment  program  described above and lower
prices being offered by the Company in response to competitive conditions in the
pharmacy benefit  management  business.  The Company also experienced an overall
reduction  as a  percentage  of net  revenues  in the fees  received  from  drug
manufacturers  in connection  with the Company's  drug  purchasing and formulary
management programs.  The decrease in gross margin in both the claims processing
and mail pharmacy services was partially offset by lower direct processing costs
due to the economies of scale for both these operations. The cost of revenue for
vision and infusion  therapy services  increased 39.6%  principally due to costs
related to the  continued  expansion  of vision  and  infusion  therapy  service
operations.

     SELLING,  GENERAL AND ADMINISTRATIVE.  Selling,  general and administrative
expenses, measured as a percentage of net revenues,  decreased from 6.4% in 1996
to 5.1% for 1997,  reflecting  overall  economies  of scale and expense  control
measures  in these areas of the  Company's  operations.  In  addition  increased
utilization of the Company's pharmacy networks, rather than networks arranged by
its clients,  resulted in higher reported net revenues,  which had the affect of
lowering the selling, general and administrative expenses as a percentage of net
revenues.  Selling,  general and  administrative  expenses increased in absolute
terms by $13,514,000,  or 27.5%,  compared to 1996, which reflects the Company's
increased  revenues  and its  continuing  commitment  to enhance  its ability to
manage the  pharmacy  benefit by investing in  information  systems,  additional
clinical programs, increased marketing effort and operational and administrative
support functions, and provide for future growth and enhanced service levels.

     OTHER INCOME,  NET. Other income, net was $5,856,000 for 1997,  compared to
$3,450,000  for 1996,  primarily as a result of higher  interest rates on larger
invested cash balances.

     PROVISION  FOR INCOME  TAXES.  The  provision for income taxes for the year
ended  December 31, 1997 was  $21,277,000,  compared to $16,932,000 in the prior
year. The effective tax rate was 38.9% in 1997 compared to 39.3% for 1996.

     NET  INCOME.  As a result of the  foregoing,  net income for the year ended
December 31, 1997, increased $7,281,000, or 27.9%, compared to 1996.

     EARNINGS PER SHARE("EPS").  The Company reported basic EPS of $2.04 in 1997
compared to $1.63 in 1996,  a 25.2%  increase.  The weighted  average  number of
shares used in the  calculations  was 16,356,000 in 1997 and 16,080,000 in 1996.
Diluted EPS was $2.02 in 1997 compared to $1.60 for 1996, a 26.3% increase.  The
weighted  average  number of shares  used in the  diluted  EPS  calculation  was
16,561,000 in 1997 and 16,350,000 in 1996.

YEAR ENDED DECEMBER 31, 1996, COMPARED TO 1995

     NET  REVENUES.  Net revenues  for 1996  increased  $229,155,000,  or 42.1%,
compared to 1995. Net revenues from the Company's claims processing services and
mail pharmacy  services  increased 41.8% in 1996,  compared to 1995. The primary
reason for this increase was a $157,609,000, or 43.7%, increase in revenues from
pharmacy  claims  processed  reflecting a 34.9% increase in the number of claims
processed,  and a 6.5% increase in average  revenue per claim  compared to 1995.
Revenue from the Company's  mail pharmacy  services  increased  $60,628,000,  or
37.5%, reflecting a 30.1% increase in the number of prescriptions dispensed, and
a 5.7% increase in the average revenue per prescription dispensed. The increases
in average revenue per claim and per prescription dispensed are primarily due to
increases in the ingredient costs of drugs for customers utilizing the Company's
pharmacy networks and mail pharmacy services,  partially offset by lower pricing
offered by the Company in response to continued competitive pressures.

     The  increase  in the  number of claims  processed  and the  number of mail
service  pharmacy  prescriptions  dispensed  reflects  a 22.2%  increase  in the
average number of members served from  approximately  8.1 million members served
at December 31, 1995 to approximately 9.9 million members served at December 31,
1996. The percentage  increase in claims processing  revenue continues to exceed
the  percentage  increase  in mail  service  revenues,  as the price  difference
between  mail  pharmacy   prescriptions   and  network  pharmacy   prescriptions
decreases.  Net revenues from the Company's vision and infusion therapy services
increased  41.0%,  compared to 1995,  as a result of the growth in the number of
members who receive these services. The Company's medical information management
subsidiary,  Practice Patterns Science,  Inc., also contributed to the Company's
progress in 1996.

     COST OF REVENUES.  Cost of revenues  for 1996  increased  $206,599,000,  or
43.2%,  compared to 1995. The  percentage  increase in cost of revenues was 1.1%
more  than the  increase  in  revenues,  thus  gross  profit  margins  decreased
slightly.  For both claims and mail pharmacy  services,  gross margin  decreased
slightly due to scheduled fee reductions  under the Company's  amended  contract
with NYLCare and as a result of competitive pressures. These factors were offset
by an increase as a percentage  of net revenues in the fees  received  from drug
manufacturers  in connection  with the Company's  drug  purchasing and formulary
management  programs and economies of scale in direct processing costs. The cost
of revenue for vision and infusion  therapy services  increased 46.2%,  which is
5.2% above the increase in revenues from these services,  compared to 1995. This
was  principally  due to costs related to the continued  expansion of vision and
infusion therapy service operations in order to serve a larger client base.

     SELLING,  GENERAL AND ADMINISTRATIVE.  Selling,  general and administrative
expenses  increased  $11,803,000,  or 31.6%,  for 1996,  compared  to 1995.  The
primary  reason for the increase  was the  additional  expenditures  incurred to
expand the Company's marketing capabilities, together with increases in expenses
for information systems, additional clinical programs and added costs for client
and  administrative  support  functions  to enhance  management  of the pharmacy
benefit.  The Company is continuing  its  commitment to expand its capability to
provide for future growth and enhance the level of service for its members.

     OTHER INCOME,  NET. Other income, net was $3,450,000 for 1996,  compared to
$757,000 for 1995,  primarily as a result of the investment of the proceeds from
the sale of 1,150,000  shares of Class A Common  Stock in April 1996,  increased
cash flow from  operations  and higher  interest rates on invested cash balances
compared to 1995.

     PROVISION  FOR INCOME  TAXES.  The  provision for income taxes for the year
ended  December 31, 1996, was  $16,932,000  compared to $11,307,000 in the prior
year. The effective tax rate was 39.3% in 1996 compared to 38.2% for 1995.

     NET  INCOME.  As a result of the  foregoing,  net income for the year ended
December 31, 1996 increased $7,821,000, or 42.7%, compared to 1995.

     EARNINGS  PER  SHARE.  The  Company  reported  basic  EPS of  $1.63 in 1996
compared to $1.23 in 1995,  a 32.5%  increase.  The weighted  average  number of
shares used in the  calculations  was 16,080,000 in 1996 and 14,871,000 in 1995,
or an increase of 8.1%.  The increase was  primarily due to the April 1996 stock
offering of 1,150,000  shares and the April 1996  issuance of 227,273  shares in
connection with the  contractual  agreement with Premier,  Inc.  Diluted EPS was
$1.60 in 1996 compared to $1.20 in 1995, a 33.3% increase.  The weighted average
number of shares used in the diluted EPS  calculation was 16,350,000 in 1996 and
15,293,000 in 1995.

LIQUIDITY AND CAPITAL RESOURCES

     The Company's  continued growth has resulted in an increase in the level of
cash flow  during  each of the last three  years of  operations.  Cash flow from
operations  totaled $52.5  million,  $29.9  million,  and $11.5 million in 1997,
1996,  and  1995,  respectively.  Management  expects  to  continue  to  fund  a
substantial  portion of its future  anticipated  capital  expenditures and other
normal  operating  cash needs with  operating  cash flow.  The Company also sold
1,150,000  shares of Class A Common  Stock in April  1996,  the net  proceeds of
which  were  $52,592,000.  These  funds and the  interest  received  to date are
currently  invested in  short-term  investments  and are  available  for general
corporate  purposes and for strategic  acquisitions or affiliations as discussed
below.

     The Company maintains a $25 million line of credit with the Mercantile Bank
National  Association,  which  was  renewed  for one year on May 29,  1997.  The
Company  has  allowed a second  line of credit in the  amount of $25  million to
lapse while it negotiates  new terms for a larger credit line (see Post Year-End
Events). Upon consummation of such larger credit facility, the Company will also
terminate the  Mercantile  Bank facility.  At December 31, 1997 and 1996,  there
were no borrowings outstanding.

     As of December 31,  1997,  the Company had  repurchased  a total of 237,500
shares  of its  Class A Common  Stock  under the  open-market  stock  repurchase
program  announced by the Company on October 25, 1996.  The  Company's  Board of
Directors  approved the repurchase of up to 850,000 shares,  and placed no limit
on the  duration  of the  program.  Future  purchases,  if any,  will be in such
amounts and at such times as the Company deems appropriate based upon prevailing
market and  business  conditions.  Management  believes  the  Company's  capital
resources are sufficient to fund this program.

     The  Company  has  reviewed  and  currently  intends  to  review  potential
acquisitions  and affiliation  opportunities  (see Other  Matters).  The Company
believes that available cash resources including the proceeds of the offering of
the Company's  common stock referred to above,  bank financings and the issuance
of  additional  common  stock  could be used to  finance  such  acquisitions  or
affiliations.  Although  the Company  entered  into a  definitive  agreement  to
acquire  Value  Health,  Inc. on February 20, 1998 (see Post  Year-End  Events),
there  can  be  no  assurance  the  Company  will  make  other  acquisitions  or
affiliations in 1998.

OTHER MATTERS

     The Company typically reports  membership both at January 1 and December 31
of each year. As many of the Company's  clients start or terminate their service
arrangements  with the Company on January 1, measurement of members on this date
is  important.  As of January 1, 1998 the Company  reported  membership  of 12.3
million  members,  a reduction of  approximately  300,000  members from the 12.6
million  members  reported on December 31, 1997.  The net  reduction  takes into
account the loss of  approximately  900,000 lives from FHP  International,  Inc.
("FHP"),  offset in part by new members  from  clients  whose  service  began on
January 1, 1998.

     On March 13, 1997,  the Company  announced that it had reached an agreement
with RightCHOICE Managed Care, Inc. ("RightCHOICE"),  a publicly held subsidiary
of Blue Cross and Blue Shield of  Missouri,  whereby the  Company  will  provide
pharmaceutical  benefit  management  services  to  RightCHOICE.  The three  year
agreement  became  effective  March 17, 1997, and covers  approximately  500,000
members.  The  agreement  also  offers the Company  the  opportunity  to provide
service to an  additional  1.4 million  members  enrolled in plans  sponsored or
administered by organizations affiliated with RightCHOICE.

     PacifiCare Health Systems, Inc. ("PacifiCare") completed its acquisition of
FHP during 1997. The Company's  contract to provide pharmacy benefit services to
FHP's members  expired  December 31, 1997. By agreement the Company will process
pharmacy claims for FHP through April 1, 1998 as FHP transitions the business to
a PBM owned by PacifiCare.  As of January 1, 1998,  approximately  900,000 lives
were  transferred to PacifiCare's  PBM. It is anticipated  another 900,000 lives
will be transferred  out by April 1, 1998.  While FHP was the Company's  largest
single client in terms of membership,  its  contribution  to the net revenues in
1997 was less than 2.25% (due to the fact that the  Company  only  recorded  the
fees related to administering  FHP's network  prescriptions and, prior to May 1,
1997,  dispensing  mail pharmacy  prescriptions),  and its  contribution  to the
Company's earnings is substantially less than the relationship of FHP membership
to total  membership.  The Company amortized the remaining amount of the advance
discount on the Class A Common Stock previously issued to FHP during 1997.

     During the third quarter of 1997,  the Company  announced  that ESI Canada,
Inc.,  the  Company's  Canadian  subsidiary,  will provide PBM services to First
Canadian  Health  Management  Corporation,  Inc.,  a  subsidiary  of Aetna  Life
Insurance  Company of Canada.  The program for which  services  will be provided
covers 640,000 registered Indians and Inuit in Canada, and will commence on July
1, 1998 and run through June 30, 2003.

     The  Company  also  announced  it had renewed its  contract  with  Coventry
Corporation for a period of two years through 1999.

     In June 1997 the FASB issued  Statement of Financial  Accounting  Standards
Statement  131  "Disclosures   about  Segments  of  an  Enterprise  and  Related
Information" ("FAS 131"). The statement requires that the Company report certain
information if specific  requirements  are met about  operating  segments of the
Company including information about services,  geographic areas of operation and
major  customers.  FAS 131 is effective for years  beginning  after December 15,
1997.  The  Company  is  reviewing  the  applicability  of FAS 131 on its future
reporting requirements.

POST YEAR-END EVENTS

     On  February  20,  1998  the  Company  announced  that  it had  executed  a
definitive  agreement  to purchase  ValueRx,  the PBM  business of  Columbia/HCA
Healthcare Corporation  ("Columbia").  Under terms of the agreement, the Company
will pay cash in the amount of $445 million for the stock of Value Health,  Inc.
and  Managed  Prescription  Network,  Inc.,  the sole assets of which at closing
shall be various subsidiaries each now or formerly conducting business as a PBM,
including   ValueRx   Pharmacy   Program,   Inc.  The  Company  expects  to  use
approximately  $100  million of its own cash and  finance the  remainder  of the
purchase  price  through a five  year  bank  facility.  In 1997,  the  unaudited
combined  revenue  of the two  companies  was in  excess  of $2.7  billion.  The
acquisition  will be  accounted  for as a purchase  and is subject to  customary
closing conditions  including required  governmental  approvals and consummation
and funding of the bank credit facility. The Company anticipates the transaction
will close in the second quarter of 1998.

     On March 16, 1998, the Company  announced that, in connection with New York
Life's sale of NYLCare to Aetna U.S. HealthCare,  Inc. ("Aetna"),  Aetna and the
Company  reached an  agreement  to extend  the  Company's  HMO PBM and  infusion
therapy  agreements  through December 31, 2003. The existing contract pricing is
effective through December 31, 1999, and thereafter certain pricing  adjustments
(which  the  Company  believes  reflect an  appropriate  market  price)  will be
instituted  for the year 2000 and subsequent  periods.  The Company will provide
PBM services to 1.4 million HMO members after the  acquisition  is  consummated,
which is approximately equal to the NYLCare HMO membership base currently served
by the Company. The infusion therapy agreements are extended under their current
terms until December 31, 2000, and thereafter limited price adjustments may take
effect under certain  circumstances.  The existing agreements for managed vision
care and informed  decision  counseling will continue through December 31, 1999.
The Company will also continue to provide PBM services to members of the NYLCare
indemnity  programs  until such members are  converted  to new health  insurance
policies.  The impact of this  arrangement on earnings per share is not expected
to be material in 1998 or 1999.

YEAR 2000 INFORMATION SYSTEMS ISSUES

     As discussed in Item 1 herein,  the Company has developed a plan to address
the Year 2000 issue and, in doing so, will incur internal staff costs as well as
external  consulting and other expenses related to  infrastructure  enhancements
necessary  to prepare its systems for the new  century.  Although the Company is
still  evaluating the overall costs  associated with the Year 2000 issue,  which
are  being  expensed  as  incurred,  the  Company  does not  believe  the  costs
associated  therewith  are or will  be  material  to the  Company's  results  of
operations or financial condition.  However,  there can be no assurance that the
Company's efforts to address the Year 2000 problem will be entirely  successful,
and the failure to fully  address  associated  issues  could  result in material
adverse  financial  consequences  to the Company.  In addition,  there can be no
assurance that the systems of other companies on which the Company's systems and
other  operations  rely will become Year 2000 compliant in a timely manner,  and
any such failure could have a material  adverse effect on the Company's  systems
and operations.

IMPACT OF INFLATION

     Changes  in  prices   charged  by   manufacturers   and   wholesalers   for
pharmaceuticals  affect the Company's net revenues and cost of revenues. To date
the Company has been able to recover price  increases from its clients under the
terms of its agreements.  As a result, changes in pharmaceutical prices have not
had a significant adverse affect on the Company.

ITEM 7A.  QUANTITATIVE AND QUALITATIVE DISCLOSURES ABOUT MARKET RISK.

Not Applicable.



ITEM 8 - CONSOLIDATED FINANCIAL STATEMENTS AND SUPPLEMENTARY DATA

                        REPORT OF INDEPENDENT ACCOUNTANTS

To the Board of Directors and
Stockholders of Express Scripts, Inc.

     In our opinion,  the consolidated  financial statements listed in the index
appearing under Item 14(a)(1) and (2) on page 42 present fairly, in all material
respects the financial position of Express Scripts, Inc. and its subsidiaries at
December 31, 1997 and 1996,  and the results of their  operations and their cash
flows for each of the three years in the period  ended  December  31,  1997,  in
conformity  with  generally  accepted  accounting  principles.  These  financial
statements   are  the   responsibility   of  the   Company's   management;   our
responsibility  is to express an opinion on these financial  statements based on
our audits.  We conducted  our audits of these  statements  in  accordance  with
generally accepted auditing standards which require that we plan and perform the
audit to obtain reasonable  assurance about whether the financial statements are
free of material  misstatement.  An audit includes  examining,  on a test basis,
evidence  supporting the amounts and  disclosures  in the financial  statements,
assessing the  accounting  principles  used and  significant  estimates  made by
management,  and evaluating the overall  financial  statement  presentation.  We
believe  that our audits  provide a reasonable  basis for the opinion  expressed
above.

/s/  Price Waterhouse LLP
St. Louis, Missouri
February 6, 1998, except for Note 13,
which is as of February 20, 1998



CONSOLIDATED BALANCE SHEET


                                                                                                     December 31,
(IN THOUSANDS, EXCEPT SHARE DATA)                                                              1997                1996
                                                                                                              
- -----------------------------------------------------------------------------------------------------------------------
Assets
Current assets:
    Cash and cash equivalents                                                            $   64,155          $   25,211
    Short-term investments                                                                   57,938              54,388
    Receivables, less allowance for doubtful
        accounts of $4,802 and  $2,335, respectively
            Unrelated parties                                                               194,061             144,963
            Related parties                                                                  16,230              18,842
    Inventories                                                                              28,935              17,491
    Deferred taxes and prepaid expenses                                                       2,649               2,254
                                                                                  --------------------------------------
            Total current assets                                                            363,968             263,149
Property and equipment, less accumulated depreciation and amortization                       26,821              21,447
Other assets                                                                                 11,719              15,829
                                                                                  -------------------------------------
            Total assets                                                                  $ 402,508           $ 300,425
                                                                                  =====================================

Liabilities and Stockholders' Equity Current liabilities:
    Claims payable                                                                        $ 153,051           $  98,865
    Accounts payable                                                                         17,979              16,347
    Accrued expenses                                                                         26,876              19,678
                                                                                  -------------------------------------
            Total current liabilities                                                       197,906             134,890
                                                                                  -------------------------------------
Deferred rents and taxes                                                                        901               1,445
                                                                                  -------------------------------------
Commitments and Contingencies (Notes 2 and 6)

Stockholders' equity:
    Preferred stock, $.01 par value, 5,000,000 shares
        authorized, and no shares issued and outstanding
    Class A Common Stock, $.01 par value, 30,000,000 shares authorized,
        9,238,000 and 8,974,000 shares issued and outstanding, respectively                      93                  90
    Class B Common Stock, $.01 par value, 22,000,000 shares authorized,
        7,510,000 shares issued and outstanding                                                  75                  75
    Additional paid-in capital                                                              106,901              98,958
    Foreign currency translation adjustments                                                   (27)                 (2)
    Retained earnings                                                                       103,648              70,219
                                                                                  -------------------------------------
                                                                                            210,690             169,340
    Class A Common Stock in treasury at cost,
        237,500 shares and 182,500 shares, respectively                                     (6,989)             (5,250)
                                                                                  -------------------------------------
            Total stockholders' equity                                                      203,701             164,090
                                                                                  -------------------------------------
            Total liabilities and stockholders' equity                                    $ 402,508           $ 300,425
                                                                                  =====================================

See accompanying Notes to Consolidated Financial Statements.



CONSOLIDATED STATEMENT OF OPERATIONS




                                                                                     Year Ended December 31,
(IN THOUSANDS, EXCEPT PER SHARE DATA)                                       1997                1996               1995
                                                                                                        
- -----------------------------------------------------------------------------------------------------------------------
Net revenues (INCLUDING $208,118, $152,311 AND
    $107,838, RESPECTIVELY FROM RELATED PARTIES)                     $ 1,230,634         $   773,615       $    544,460
                                                              ---------------------------------------------------------
Cost and expenses:
    Cost of revenues                                                   1,119,167             684,882            478,283
    Selling, general and administrative                                   62,617              49,103             37,300
                                                              ---------------------------------------------------------
                                                                       1,181,784             733,985            515,583
                                                              ---------------------------------------------------------
Operating income                                                          48,850              39,630             28,877
                                                              ---------------------------------------------------------
Other income (expense):
    Interest income                                                        6,081               3,509                843
    Interest expense                                                       (225)                (59)               (86)
                                                              ---------------------------------------------------------
                                                                           5,856               3,450                757
                                                              ---------------------------------------------------------
Income before income taxes                                                54,706              43,080             29,634
Provision for income taxes                                                21,277              16,932             11,307
                                                              ---------------------------------------------------------
Net income                                                           $    33,429         $    26,148        $    18,327
                                                              =========================================================
Basic earnings per share                                             $      2.04         $      1.63        $      1.23
                                                              =========================================================
Weighted average number of common shares
    outstanding during the period - Basic EPS                             16,356              16,080             14,871
                                                              =========================================================
Diluted earnings per share                                           $      2.02          $     1.60         $     1.20
                                                              =========================================================
Weighted average number of common shares outstanding
    during the period - Diluted EPS                                       16,561              16,350             15,293
                                                              =========================================================
See accompanying Notes to Consolidated Financial Statements.





CONSOLIDATED CHANGES IN STOCKHOLDERS' EQUITY



                                Number of Shares                                    Amount
                               -------------------     ------------------------------------------------------------------------
                                                                                               Foreign
                                Class A    Class B        Class A     Class B    Additional    Currency
                                 Common     Common        Common      Common      paid-in    Translation   Retained    Treasury
(IN THOUSANDS)                   Stock      Stock         Stock       Stock       capital     Adjustment   Earnings      Stock
                                                                                                    
- --------------------------------------------------     ------------------------------------------------------------------------
Balance at December 31, 1994      4,242     10,500            $42        $105    $26,594           -       $25,744          -
    Net income                        -          -              -           -          -           -        18,327          -
    Issuance of Class A
        Common Stock                 25          -              -           -        684           -             -          -
    Exercise of stock options       272          -              3           -      2,308           -             -          -
    Tax benefit relating to
      employee stock options          -          -              -           -      3,572           -             -          -
                              ------------------------------------------------------------------------------------------------
Balance at December 31, 1995      4,539     10,500             45         105     33,158           -        44,071          -
    Net income                        -          -              -           -          -           -        26,148          -
    Conversion of Class B
        Common Stock to
        Class A Common Stock      2,990    (2,990)             30        (30)          -           -             -          -
    Issuance of Class A
        Common Stock
            Contractual agreement   227          -              2           -     11,250           -             -          -
            Public offering       1,150          -             12           -     52,580           -             -          -
    Exercise of stock options        68          -              1           -      1,309           -             -          -
    Tax benefit relating to
        employee stock options        -          -              -           -        661           -             -          -
    Treasury Stock acquired           -          -              -           -          -           -             -     $(5,250)
    Foreign currency transalation
         adjustment                   -          -              -           -          -        $(2)             -          -
                              -------------------------------------------------------------------------------------------------
Balance at December 31, 1996      8,974      7,510             90          75     98,958         (2)        70,219      (5,250)
    Net income                        -          -              -           -          -           -        33,429          -
    Exercise of stock options       264          -              3           -      4,769           -             -          -
    Tax benefit relating to
        employee stock options        -          -              -           -      3,174           -             -          -
    Treasury Stock acquired           -          -              -           -          -           -             -      (1,739)
    Foreign currency translation      -          -              -           -          -                         -          -
        adjustment                                                                               (25)
                              -------------------------------------------------------------------------------------------------
Balance at December 31, 1997      9,238      7,510            $93         $75   $106,901        $(27)     $103,648     $(6,989)
                              =================================================================================================


See accompanying Notes to Consolidated Financial Statements.



CONSOLIDATED STATEMENT OF CASH FLOWS




                                                                                     Year Ended December 31,
(IN THOUSANDS)                                                              1997                1996               1995
                                                                                                           
- -----------------------------------------------------------------------------------------------------------------------
 Cash flows from operating activities:
    Net income                                                          $ 33,429            $ 26,148           $ 18,327
    Adjustments to reconcile net income to net
    cash provided by operating activities:
        Depreciation and amortization                                     10,470               6,707              4,381
        Tax benefit relating to employee stock options                     3,174                 661              3,572
        Changes in operating assets and liabilities:
            Receivables                                                 (46,486)            (46,693)           (39,304)
            Inventories                                                 (11,444)             (3,638)            (4,904)
            Prepaid expenses and other assets                                888             (2,787)              (844)
            Claims payable                                                54,186              37,950             22,206
            Accounts payable and accrued expenses                          8,286              11,515              8,066
                                                              ---------------------------------------------------------
Net cash provided by operating activities                                 52,503              29,863             11,500
                                                              ---------------------------------------------------------

Cash flows from investing activities:
    Acquisition of new business                                                -               (940)                 -
    Short-term investments                                               (3,550)            (54,388)                 -
    Purchases of property and equipment                                 (13,017)             (9,480)            (8,047)
                                                              ---------------------------------------------------------
Net cash (used in) investing activities                                 (16,567)            (64,808)            (8,047)
                                                              ---------------------------------------------------------

Cash flows from financing activities:
    Proceeds from stock offering                                               -              52,592                  -
    Acquisition of Treasury Stock                                        (1,739)             (5,250)                  -
    Exercise of stock options                                              4,772               1,310              2,311
                                                              ---------------------------------------------------------
Net cash provided by financing activities                                  3,033              48,652              2,311
                                                              ---------------------------------------------------------

Effect of foreign currency translation adjustment                           (25)                 (2)                  -
                                                              ---------------------------------------------------------

Net increase in cash and cash equivalents                                 38,944              13,705              5,764
Cash and cash equivalents at beginning of year                            25,211              11,506              5,742
                                                              ---------------------------------------------------------
Cash and cash equivalents at end of year                                $ 64,155            $ 25,211          $  11,506
                                                              =========================================================


See accompanying Notes to Consolidated Financial Statements.



NOTES TO CONSOLIDATED FINANCIAL STATEMENTS

    1. SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES

     The significant  accounting policies followed by Express Scripts,  Inc. are
described below. The policies  utilized by the Company in the preparation of the
financial  statements conform to generally accepted accounting  principles,  and
require  management to make estimates and  assumptions  that affect the reported
amounts of assets and  liabilities  at the date of the financial  statements and
the  reported  amounts of revenues  and expenses  during the  reporting  period.
Actual amounts could differ from those estimates and assumptions.

     PRINCIPLES OF CONSOLIDATION.  The consolidated financial statements include
the accounts of the Company and all majority owned subsidiaries. All significant
inter-company accounts and transactions have been eliminated.

     FOREIGN CURRENCY TRANSLATION. Adjustments resulting from the translation of
financial  statements  are  reflected as a separate  component of  stockholders'
equity.

     ORGANIZATION AND OPERATIONS.  The Company currently derives the majority of
its revenues,  including claims processing fees, principally from domestic sales
of  prescription  drugs by its mail  pharmacies  and pharmacies in the Company's
nationwide  networks.  Effective in January 1996,  the Company began  processing
claims for clients of its wholly-owned  Canadian  subsidiary,  ESI Canada,  Inc.
("ESI  Canada").  The Company also derives  revenues from (i) informed  decision
counseling services through its Express Health LineSM division, (ii) the sale of
pharmaceuticals  for and the provision of infusion  therapy services through its
IVTx division,  (iii) medical  information  management  services,  which include
provider profiling, disease management support services and outcomes assessments
through  its  Practice  Patterns  Science,  Inc.  subsidiary,  and (iv) sales of
eyeglasses and contact lenses and associated administrative fees to participants
in the Company's  managed  vision  programs  operated by Express  Scripts Vision
Corporation.

     In March 1992, the Company,  which was originally  incorporated in Missouri
in 1986,  was  reincorporated  in Delaware and issued an aggregate of 10,500,000
shares  of Class B Common  Stock to Sanus  Corp.  Health  Systems  ("Sanus")  in
exchange for the outstanding  shares of its common stock. Sanus at that time was
an  indirect  subsidiary  of New York  Life.  In April  1992,  as a result  of a
reorganization,  both the Company and Sanus became direct subsidiaries of NYLIFE
HealthCare  Management,  Inc.  ("NYLIFE").  Sanus has since  changed its name to
NYLCare  Health  Plans,  Inc.  ("NYLCare").  In  April  1996,  NYLIFE  converted
2,990,000  Class B shares  to Class A Common  Stock and sold  those  shares in a
public offering.  NYLIFE continues to own all the remaining  outstanding Class B
Common Stock of the Company (see Note 9).

     CONTRACTUAL  AGREEMENTS.  The Company enters into corporate  alliances with
certain of its clients  whereby shares of the Company's Class A Common Stock are
awarded as advance  discounts  to the  clients.  The Company  accounts for these
agreements as follows:

     PRIOR TO DECEMBER 15, 1995 - For agreements  consummated  prior to December
15, 1995, the stock is valued  utilizing the quoted market value at the date the
agreement is consummated  if the number of shares to be issued is known.  If the
number  of  shares to be issued  is  contingent  upon the  occurrence  of future
events,  the stock is valued  utilizing  the quoted market value at the date the
contingency is satisfied and the number of shares is determinable.

     BETWEEN  DECEMBER 15, 1995 AND NOVEMBER 20, 1997 - For  agreements  entered
into between  these dates,  the Company  utilizes  the  provisions  of Financial
Accounting   Standards   Board   Statement  123   "Accounting   for  Stock-Based
Compensation"  ("FAS 123") which requires that all stock issued to  nonemployees
be accounted  for based on the fair value of the  consideration  received or the
fair value of the equity  instruments  issued  instead  of the  intrinsic  value
method  utilized for stock issued or to be issued under  alliances  entered into
prior to  December  15,  1995.  The Company has adopted FAS 123 as it relates to
stock issued or to be issued under the Premier and Manulife  alliances  based on
fair value at the date the agreement was consummated.

     SUBSEQUENT  TO NOVEMBER 20, 1997 - In November  1997,  the Emerging  Issues
Task Force reached a consensus that the value of equity  instruments  issued for
consideration other than employee services should be initially determined on the
date on which a "firm  commitment" for performance  first exists by the provider
of goods or services.  Firm  commitment  is defined as a commitment  pursuant to
which  performance  by a provider of goods or  services  is probable  because of
sufficiently  large  disincentives  for  nonperformance.  The consensus  must be
applied for all new  arrangements  and  modifications  of existing  arrangements
entered into from November 20, 1997.  The consensus only addresses the date upon
which fair value is  determined  and does not change the  accounting  based upon
fair value as prescribed by FAS 123. No such arrangements have been entered into
by the Company subsequent to November 20, 1997.

     Shares  issued  on the  effective  date of the  contractual  agreement  are
considered  outstanding  and  included in basic and diluted  earnings  per share
computations  when issued.  Shares  issuable  upon the  satisfaction  of certain
conditions  are  considered  outstanding  and included in the earnings per share
computation  as discussed  in the  "Earnings  per share" note.  The value of the
shares of stock awarded as advance  discounts is recorded as a deferred cost and
included in Other Assets.  The deferred  cost is recognized in Selling,  General
and Administrative expenses over the period of the contract.

     CASH AND CASH EQUIVALENTS.  Cash and cash equivalents  include cash on hand
and  temporary  investments  in money market  funds.  Due to the nature of these
instruments, the carrying amount approximates fair value.

     SHORT-TERM INVESTMENTS.  Short-term investments consists of debt securities
with a maturity of less than one year that the Company has the  positive  intent
and  ability to hold to  maturity  and are  reported at  amortized  cost,  which
approximates fair market value.

     INVENTORIES. Inventories consist of prescription drugs, vision supplies and
medical  supplies  that are stated at the lower of  first-in  first-out  cost or
market.

     PROPERTY AND  EQUIPMENT.  Property and  equipment is carried at cost and is
depreciated using the straight-line  method over estimated useful lives of seven
years for furniture,  five years for equipment and purchased  computer  software
and three years for personal computers.  Leasehold improvements are amortized on
a  straight-line  basis  over the term of the  lease or the  useful  life of the
asset,  if shorter.  Expenditures  for  repairs,  maintenance  and  renewals are
charged to income as incurred. Expenditures which improve an asset or extend its
estimated useful life are capitalized.  When properties are retired or otherwise
disposed of, the related cost and accumulated  depreciation are removed from the
accounts and any gain or loss is included in income.

     SOFTWARE DEVELOPMENT COSTS. Research and development  expenditures relating
to the  development  of software  to be  marketed to clients,  or to be used for
internal  purposes,  are charged to expense until  technological  feasibility is
established.  Thereafter, the remaining software production costs up to the date
of general  release to  customers,  or to the date placed into  production,  are
capitalized and included as Property and Equipment.  During 1997, 1996 and 1995,
$1,982,000,  $1,898,000,  and  $1,084,000  in  software  development  costs were
capitalized,  respectively.  Capitalized  software development costs amounted to
$5,269,000  and  $3,377,000  at  December  31,  1997  and  1996,   respectively.
Amortization of the capitalized amounts commences on the date of general release
to  customers,  or  the  date  placed  into  production,  and is  computed  on a
product-by-product  basis  using the  straight-line  method  over the  remaining
estimated economic life of the product but not more than five years. Reductions,
if any, in the carrying  value of  capitalized  software costs to net realizable
value are also  included  in  amortization  expense.  Amortization  expense  was
$622,000 in 1997 and $136,000 in 1996. No  amortization  expense was recorded in
1995.

     GOODWILL.  Goodwill is  amortized on a  straight-line  basis over a fifteen
year period.  Amortization expense was $42,000 for each of the three years ended
December 31, 1997, 1996 and 1995.

     IMPAIRMENT OF LONG LIVED ASSETS.  The Company  evaluates whether events and
circumstances have occurred that indicate the remaining estimated useful life of
long lived assets may warrant revision or that the remaining balance of an asset
may not be recoverable.  The measurement of possible  impairment is based on the
ability to recover the balance of assets from  expected  future  operating  cash
flows on an undiscounted basis. In the opinion of management, no such impairment
existed as of December 31, 1997 or 1996.

     REVENUE   RECOGNITION.    Revenues   from   dispensing   prescription   and
non-prescription medical products from the Company's mail service pharmacies are
recorded upon shipment.  Revenue from sales of prescription  drugs by pharmacies
in the Company's  nationwide network and pharmacy claims processing revenues are
recognized   when  the  claims  are  processed.   When  the  Company   dispenses
pharmaceuticals  to members of health  benefit plans  sponsored by the Company's
clients or has an independent contractual obligation to pay its network pharmacy
providers  for  benefits  provided to members of its clients'  pharmacy  benefit
plans,  the Company  includes  payments from plan sponsors for these benefits as
net revenue and ingredient costs or payments to these pharmacy providers in cost
of revenues.  If the Company is only  administering  the plan sponsors'  network
pharmacy contracts, or where the Company dispenses  pharmaceuticals  supplied by
one of the Company's  clients,  the Company records only the  administrative  or
dispensing  fees derived from the Company's  contracts with the plan sponsors as
net revenue.

     COST OF REVENUES.  Cost of revenues includes product costs, pharmacy claims
payments and other direct costs  associated  with dispensing  prescriptions  and
non-prescription  medical products and claims processing  operations,  offset by
fees received from pharmaceutical manufacturers in connection with the Company's
drug purchasing and formulary management programs.

     INCOME TAXES.  The Company accounts for income taxes in accordance with the
provisions of Statement of Financial  Accounting  Standards No. 109, "Accounting
for Income  Taxes"  ("FAS 109").  Under FAS 109,  the deferred tax  provision is
determined under the liability  method.  Under this method,  deferred assets and
liabilities  are recognized  based on temporary  differences  between  financial
statement basis and tax basis of assets and liabilities  using presently enacted
tax rates.

     EARNINGS PER SHARE.  In February 1997, the Financial  Accounting  Standards
Board issued  Statement 128  "Earnings Per Share" ("FAS 128").  The terms of FAS
128 are effective for all earnings per share disclosures  subsequent to December
15,  1997 and  requires  all prior  period  earnings  per share  disclosures  be
restated  to  conform  with FAS 128.  FAS 128  requires a  presentation  of both
"Basic"  earnings per share and "Diluted"  earnings per share.  "Basic" earnings
per share  computes  per share  earnings  using the weighted  average  number of
common shares outstanding during the period,  while "Diluted" earnings per share
computes  per share  earnings in the same manner as "Basic"  earnings  per share
plus the number of additional common shares that would have been outstanding for
the period if the dilutive  potential  common  shares had been issued.  The only
difference  between the number of weighted  average shares used in the basic and
diluted  calculation for all years is stock options granted by the Company using
the "treasury stock" method,  amounting to 205,000, 270,000 and 422,000 in 1997,
1996 and 1995,  respectively.  The Company  has  adopted  FAS 128  listing  both
"Basic"  earnings  per  share  and  "Diluted"  earnings  per share for all years
presented in the financial statements.

     Shares  issuable  upon  the   satisfaction  of  conditions  are  considered
outstanding  and included in the computation of - BASIC EARNINGS PER SHARE as of
the date that all necessary  conditions  have been satisfied - DILUTED  EARNINGS
PER SHARE - if all necessary  conditions  have been  satisfied by the end of the
period - if all necessary  conditions  have not been satisfied by the end of the
period, the number of shares included are based on the number of shares, if any,
that would be  issuable if the end of the  reporting  period were the end of the
contingency period and if the result would be dilutive.

     EMPLOYEE STOCK-BASED COMPENSATION.  The Company accounts for employee stock
options  in  accordance  with  Accounting  Principles  Board No. 25 ("APB  25"),
"Accounting  for Stock Issued to Employees."  Under APB 25, the Company  applies
the intrinsic  value method of  accounting  and,  therefore,  does not recognize
compensation expense for options granted,  because options are only granted at a
price equal to market value at the time of grant.  During  1996,  FAS 123 became
effective for the Company.  FAS 123 prescribes the  recognition of  compensation
expense  based on the fair  value  of  options  determined  on the  grant  date.
However,  FAS 123 grants an exception that allows companies  currently  applying
APB 25 to continue  using that method.  The Company has,  therefore,  elected to
continue  applying the intrinsic  value method under APB 25. For companies  that
choose to continue applying the intrinsic value method, FAS 123 mandates certain
pro forma  disclosures  as if the fair value method had been  utilized (see Note
10).

     2. CONTRACTUAL AGREEMENTS

     On  December  31,  1995,  the  Company  entered  into a ten-year  corporate
alliance with Premier Purchasing Partners,  L.P. (formerly,  American Healthcare
Systems Purchasing Partners, L.P., the "Partnership"),  an affiliate of Premier,
Inc.  ("Premier").  Premier is the alliance of healthcare systems resulting from
the merger in 1995 of American Healthcare  Systems,  Premier Health Alliance and
SunHealth Alliance. Under the terms of the transaction, the Company is Premier's
preferred   vendor  of  pharmacy  benefit   management   services  to  Premier's
shareholder  systems and their managed care  affiliates and will issue shares of
its Class A Common Stock as an  administrative  fee to the Partnership  based on
the  attainment  of  certain  benchmarks,  principally  related to the number of
members receiving the Company's pharmacy benefit  management  services under the
arrangement,  and to the  achievement  of certain  joint  purchasing  goals.  In
accordance with the terms of the agreement, the Company issued 227,273 shares of
Class A Stock to Premier in May,  1996,  and may be  required  to issue up to an
additional  2,250,000  shares to the  Partnership  over a period up to the first
five years of the  agreement  if the  Partnership  exceeds all  benchmarks.  The
shares  issued  were  valued at  $11,250,000  and are being  amortized  over the
remaining term of the agreement.  Amortization expense amounted to $1,164,000 in
1997 and $776,000 in 1996. Except for certain exemptions from registration under
the 1933 Act, any shares issued to the  Partnership  cannot be traded until they
have been  registered  under the  Securities  Act of 1933, as amended (the "1933
Act") and any applicable state securities laws. No stock was issued in 1997.

     Effective January 1, 1996, the Company executed a multi-year  contract with
The Manufacturers  Life Insurance Company  ("Manulife"),  to introduce  pharmacy
benefit  management  services  in Canada.  Manulife's  Group  Benefits  Division
continues to work with ESI Canada to provide these services.  Under the terms of
the  agreement,  the  Company  will be the  exclusive  third-party  provider  of
pharmacy benefit management services to Manulife's Canadian clients. The Company
also will issue  shares of its Class A Common  Stock as an advance  discount  to
Manulife based upon  achievement of certain volumes of Manulife  pharmacy claims
processed by the  Company.  No shares will be issued until after the fourth year
of the agreement based on volumes reached in years two through four. The Company
anticipates  issuing no more than 237,000 shares to Manulife over a period up to
the  first  six years of the  agreement.  Except  for  certain  exemptions  from
registration  under the 1933 Act, any shares issued to Manulife cannot be traded
until  they have been  registered  under the 1933 Act and any  applicable  state
securities  laws. In accordance  with the terms of the  agreement,  no stock was
issued in 1997 or 1996.

     If Manulife has not exercised an early termination option at the end of the
sixth or tenth year of the  agreement,  the Company  will issue at each of those
times a ten-year  warrant as an advance discount to purchase up to approximately
118,000  additional  shares of the Company's Class A Common Stock exercisable at
85% of the market  price at those times.  The actual  number of shares for which
such warrant is to be issued is based on the volume of Manulife  pharmacy claims
processed by the Company in year six and year ten, respectively.

     Pursuant to an agreement with Coventry  Corporation,  an operator of health
maintenance  organizations  located principally in Pennsylvania and Missouri, on
January 3, 1995,  the Company issued 25,000 shares of Class A Common Stock as an
advance discount to Coventry in a private placement. These shares were valued at
$27.38 per share,  the per share  market value of the  Company's  Class A Common
Stock on November 22, 1994, which was the date the agreement was consummated and
the  obligation  of  the  parties  became  unconditional.  No  revision  of  the
consideration for the transaction occurred between November 22, 1994 and January
3, 1995.  The shares  issued to  Coventry  are being  amortized  over a six-year
period.  Amortization  expense  was  $114,000  for each of the three years ended
December  31,  1997,  1996  and  1995.   Except  for  certain   exemptions  from
registration  under the 1933 Act,  these shares cannot be traded until they have
been registered  under the 1933 Act and any applicable  state  securities  laws.
Effective  January 1, 1998,  Coventry  renewed the agreement for a two-year term
through December 31, 1999. As part of the agreement, the Company issued warrants
as an advance discount to purchase an additional  25,000 shares of the Company's
Class A Common  Stock,  exercisable  at 90% of the  market  value at the time of
renewal.

     On October 13, 1992, the Company entered into a five-year  arrangement with
FHP,  Inc.  ("FHP")  pursuant  to which the Company  agreed to provide  pharmacy
benefit  services  to  FHP  and  its  members.  FHP  is an  operator  of  health
maintenance  organizations,   principally  in  the  western  United  States.  In
accordance with the agreement,  the Company commenced providing pharmacy benefit
services to FHP and its members on January 4, 1993. On the commencement date and
pursuant to the  agreement,  the Company  issued  200,000  shares of its Class A
Common Stock as advance  discounts to FHP in a private  placement.  These shares
were  valued at $8.25 per share,  the per share  market  value of the  Company's
Class A shares  on  October  13,  1992,  which  was the date the  agreement  was
consummated and the obligations of the parties became unconditional. No revision
of the consideration  for the transaction  occurred between October 13, 1992 and
January  4,  1993.  In  February   1997,   PacifiCare   Health   Systems,   Inc.
("PacifiCare") completed the acquisition of FHP. As a result of the acquisition,
PacifiCare  informed  the  Company  that it would  not  enter  into a  long-term
extension  of the  agreement  and has reached an  agreement  with the Company to
phase-out  membership  beginning July 1997 and continuing  until April 1998. The
cost of the shares issued to FHP was amortized over a five-year  period.  Due to
the  termination  of the  agreement,  the  unamortized  balance of $990,000  was
written off in 1997. Amortization expense was $165,000 in 1996 and 1995.

     3. RELATED PARTY TRANSACTIONS

     The Company has agreements to provide claims  processing  services and mail
pharmacy  prescription  services  for  NYLCare,  in return for which it receives
processing fees and reimbursement for the contracted cost of the claims. Cost of
revenues from related parties were $176,761,000, $122,157,000 and $82,903,000 in
1997, 1996 and 1995, respectively.

The  amount  receivable  from or (due to)  related  parties  comprised  the
following:



                                                                           December 31,
(IN THOUSANDS)                                                      1997                    1996
                                                                                       
- ------------------------------------------------------------------------------------------------
Receivable from NYLCare                                         $ 23,709                $ 23,083
Due to NYLCare                                                   (7,479)                 (4,241)
                                                  ----------------------------------------------
Total related party receivable                                  $ 16,230                $ 18,842
                                                  ==============================================

Changes in amounts due to NYLCare are summarized as follows:



(IN THOUSANDS)                                                      1997                    1996                   1995
                                                                                                           
- -----------------------------------------------------------------------------------------------------------------------
Beginning balance, January 1                                    $  4,241               $   5,578             $    4,328
Formulary fees                                                    11,690                   7,636                  5,895
Other, net                                                             -                       -                    968
Payments                                                         (8,452)                 (8,973)                (5,613)
                                                  ---------------------------------------------------------------------
Ending balance, December 31                                     $  7,479                $  4,241              $   5,578
                                                  =====================================================================


     The  Company is the  exclusive  provider  of  pharmacy  benefit  management
services  to  NYLCare's  managed  healthcare  subsidiaries,  subject  to certain
exceptions.  Currently,  the Company's agreement with NYLCare also provides that
fees  from  drug  manufacturers   whose  products  are  used  in  the  Company's
formularies  related  to  NYLCare  subsidiaries  will be  allocated  100% to the
Company up to $400,000 and 75% to NYLCare and 25% to the Company thereafter. The
Company  is also the  non-exclusive  provider  of  pharmacy  benefit  management
services for insurance  plans  underwritten  and  administered by NYLCare (these
plans were  underwritten and administered by New York Life prior to its internal
reorganization pursuant to which it transferred all of its group life and health
insurance business,  along with its PBM agreement with the Company, to NYLCare).
In 1996  fees  from  drug  manufacturers  with  respect  to this  business  were
allocated  100% to the Company.  Effective  January 1, 1997,  the Company shared
such fees with NYLCare on a fixed per script  amount which  approximates  40% of
the total of such fees.

     Such fees allocated to NYLCare were $11,690,000,  $7,636,000 and $5,895,000
in 1997, 1996 and 1995,  respectively.  The Company's  portion of such fees were
$5,803,000,  $3,064,000 and $2,553,000 in 1997, 1996 and 1995, respectively. The
portion  of the  fees  retained  by  the  Company  has  been  classified  in the
accompanying  consolidated  statement  of  operations  as a reduction of cost of
revenues.

     4. PROPERTY AND EQUIPMENT

Property and equipment, at cost, consists of the following:


                                                                             December 31,
(IN THOUSANDS)                                                      1997                    1996
                                                                                       
- ------------------------------------------------------------------------------------------------
Furniture                                                      $   4,362               $   3,203
Equipment                                                         28,924                  21,837
Computer software                                                 12,011                   8,656
Leasehold improvements                                             3,934                   2,699
                                                  ----------------------------------------------
                                                                  49,231                  36,395
Less accumulated depreciation and
    amortization                                                  22,410                  14,948
                                                  ----------------------------------------------
                                                                $ 26,821                $ 21,447
                                                  ==============================================



     5. INCOME TAXES

The income tax provision consists of the following:



                                                                                Year Ended December 31,
(IN THOUSANDS)                                                      1997                    1996                   1995
                                                                                                           
- -----------------------------------------------------------------------------------------------------------------------
Current provision:
    Federal                                                     $ 19,048              $   13,945                $ 9,951
    State                                                          2,779                   2,480                  1,656
    Foreign                                                          284                     190                      -
                                                  ---------------------------------------------------------------------
        Total current provision                                   22,111                  16,615                 11,607
Deferred:
    Federal                                                        (714)                     267                  (259)
    State                                                          (120)                      50                   (41)
                                                  ---------------------------------------------------------------------
                                                                $ 21,277                $ 16,932               $ 11,307
                                                  =====================================================================
Effective tax rate                                                 38.9%                   39.3%                  38.2%



The  effective  tax rate is  comprised  of a federal rate of 35.0% in 1997,
1996 and 1995,  state taxes net of federal  benefit of 3.8%,  4.3%,  and 3.5% in
1997, 1996 and 1995,  respectively;  and all other items  comprising 0.1%, 0.0%,
and (0.3%) in 1997, 1996 and 1995, respectively.  The effect of foreign taxes on
the effective tax rate for 1997 and 1996 is immaterial.



The deferred tax assets and deferred tax liabilities recorded in the
consolidated balance sheet are as follows:




                                                                             December 31,
(IN THOUSANDS)                                                      1997                    1996
                                                                                       
- ------------------------------------------------------------------------------------------------
Deferred Tax Assets:
   Inventory costing capitalization and reserves              $      675               $     624
   Allowance for bad debts                                         1,578                     969
   Employee compensation                                             512                       -
   Other                                                              79                      34
                                                  ----------------------------------------------
       Gross deferred tax assets                                   2,844                   1,627
                                                  ----------------------------------------------
Deferred Tax Liabilities:
   Depreciation and property differences                         (1,166)                 (1,169)
   Other                                                            (91)                   (217)
                                                  ----------------------------------------------
       Gross deferred tax liabilities                            (1,257)                 (1,386)
                                                  ----------------------------------------------

Net deferred tax assets                                         $  1,587                $    241
                                                  ==============================================



The Company made cash payments for federal and state income taxes of
$20,691,000, $14,544,000 and $7,548,000 in 1997, 1996 and 1995, respectively.

    6. COMMITMENTS AND CONTINGENCIES

     The Company leases office and  distribution  facility space under operating
leases.  The primary  leases are for office and  distribution  facilities in St.
Louis,  Missouri,  and Tempe, Arizona. The St. Louis facility is under a 16-year
lease  which  commenced  November  1992,  and the  facility  in Tempe is under a
15-year lease which commenced  November 1993. The Company also leases  satellite
offices for certain other Company  operations for varying periods up to 5 years.
The  aggregate  minimum lease  commitment  is $1,883,000 in 1998,  $1,863,000 in
1999,   $1,859,000  in  2000,  $1,785,000  in  2001,  $1,600,000  in  2002,  and
$10,169,000 in years thereafter.

     For the year ended December 31, 1997,  approximately 66.0% of the Company's
pharmaceutical purchases were through one wholesaler.  The Company believes that
other alternative sources are readily available.

     In the  ordinary  course of  business,  there  have  arisen  various  legal
proceedings,  investigations  or claims  pending  against  the  Company  and its
subsidiaries.  The effect of these  actions on future  financial  results is not
subject to reasonable  estimation because considerable  uncertainty exists about
the  outcomes.   Nevertheless,  in  the  opinion  of  management,  the  ultimate
liabilities  resulting  from any such  lawsuits,  investigations  or claims  now
pending will not materially affect the consolidated financial position,  results
of operations or cash flows of the Company.

     7. CREDIT AGREEMENT

     The  Company  maintains  a  $25,000,000  unsecured  line of credit with the
Mercantile Bank National  Association  which was renewed for one year on May 29,
1997.  The  Company  has  allowed a second  line of credit in the  amount of $25
million to lapse as of October 31,  1997.  Terms of the  Mercantile  Bank credit
agreement  are  as  follows:   interest  is  charged  on  the  principal  amount
outstanding  at a rate equal to any of the following  options which the Company,
at its option shall select:  (i) the bank's  "prime rate",  (ii) a floating rate
equal to the Bank's  cost of funds rate plus 50 basis  points,  or (iii) a fixed
rate for periods of 30, 60, 90 or 180 days equal to the LIBOR rate plus 50 basis
points.  Fees under this  agreement  on any unused  portion  are  charged at ten
one-hundredths  of one percent  per year.  At  December  31, 1997 and 1996,  the
Company had no outstanding  borrowings  under this agreement,  nor did it borrow
any amounts under these agreements during 1997.



     8. RETIREMENT PLAN

     The Company offers all of its full-time employees a retirement savings plan
under Section 401(k) of the Internal Revenue Code.  Employees may elect to enter
into a written salary  deferral  agreement under which a maximum of 10% of their
salary,  subject to aggregate  limits required under the Internal  Revenue Code,
may be  contributed  to the plan. In 1994,  the Company began matching the first
$1,000 of the employee's  contribution for the year.  Effective January 1, 1996,
the  Company's  match  was  increased  to the  first  $2,000  of the  employee's
contribution  for the year. For the year ended December 1997, 1996 and 1995, the
Company made  contributions  of approximately  $909,000,  $639,000 and $332,000,
respectively.

     9. COMMON STOCK

     The  holders  of Class A Common  Stock  have  one vote per  share,  and the
holders of Class B Common  Stock  have ten votes per  share.  NYLIFE is the sole
holder of Class B Common  Stock.  Class B Common  Stock  converts  into  Class A
Common Stock on a  share-for-share  basis upon transfer  (other than to New York
Life or its  affiliates) and is convertible at any time in the discretion of the
holder.  At December  31,  1997,  NYLIFE and the holders of Class A Common Stock
have control over approximately 89.1% and 10.9%,  respectively,  of the combined
voting power of all classes of Common Stock.

     In April 1996, NYLIFE converted 2,990,000 shares of Class B Common Stock to
Class A Common  Stock  and sold the  Class A shares  in a public  offering.  The
Company did not receive any proceeds from the sale of these shares.  The Company
sold an  additional  1,150,000  Class A shares in the same  stock  offering  and
received  net  proceeds of  $52,592,000  after  deducting  expenses  incurred in
connection with the offering.

     As of December 31, 1997,  2,754,000  shares of the Company's Class A Common
Stock have been  reserved for issuance to  organizations  with which the Company
has signed contractual agreements (see Note 2).

     10. STOCK OPTION PLANS

     At December 31, 1997, the Company has three fixed stock-based  compensation
plans, which are described below.

     In April 1992,  the Company  adopted a stock  option plan  amended in 1995,
which provides for the grant of  nonqualified  stock options and incentive stock
options  to  officers  and  key  employees  of  the  Company   selected  by  the
Compensation  Committee  of the Board of  Directors.  Initially,  a  maximum  of
700,000  shares of Class A Common  Stock  could be issued  under the plan.  That
amount increases  annually each January 1, from January 1, 1993 to and including
January 1, 1999 by 70,000,  to a maximum of 1,190,000  shares. In June 1994, the
Board of Directors  adopted the Express  Scripts,  Inc.  1994 Stock Option Plan,
also amended in 1995 and 1997. The plan was approved by the stockholders in June
1995. A total of 460,000  shares of the Company's  Class A Common Stock has been
reserved for issuance  under this plan. In January 1998,  the Board of Directors
of the Company  approved an amendment to such stock option plan  providing  that
the total number of shares  reserved for issuance under the plan be increased to
960,000,  subject to approval by the Company's  shareholders  at the 1998 Annual
Meeting of  Shareholders.  Under either plan,  the exercise price of the options
may not be less than the fair  market  value of the shares at the time of grant.
The Committee may establish  vesting terms in its discretion,  and has typically
provided  that  options  vest  over a  five  year  period.  The  options  may be
exercised,  subject  to a  ten-year  maximum,  over a period  determined  by the
Committee.

     In April  1992,  the  Company  also  adopted a stock  option plan which was
amended  in 1995 and 1996  and  provides  for the  grant of  nonqualified  stock
options to purchase 24,000 shares to each director who is not an employee of the
Company or its  affiliates.  A maximum of 192,000 shares of Class A Common Stock
may be issued  under this plan at a price equal to fair market value at the date
of grant. Options vest over a five-year period from the date of grant.

     The Company  applies APB 25 and related  interpretations  in accounting for
its plans.  Accordingly,  no compensation cost has been recognized for its stock
option plans. Had compensation  cost for the Company's stock based  compensation
plans  been  determined  based on the fair  value at the grant  dates for awards
under  those  plans  consistent  with the  method  prescribed  by FAS  123,  the
Company's  net income and  earnings per share would have been reduced to the pro
forma amounts  indicated below. Note that due to the adoption of the methodology
prescribed by FAS 123, the pro forma results shown below only reflect the impact
of options granted in 1997, 1996 and 1995. Because future options may be granted
and vesting typically occurs over a five year period, the pro forma impact shown
for  1997,  1996 and 1995 is not  necessarily  representative  of the  impact in
future years.




                                   1997             1996           1995
                                                            
                           ---------------------------------------------
Net income
   As reported              $33,429,000      $26,148,000     $18,327,000
   Pro forma                 32,034,000       25,235,000      18,220,000

Basic earnings per share
   As reported                    $2.04            $1.63          $1.23
   Pro forma                       1.96             1.58           1.23

Diluted earnings per share
   As reported                    $2.02            $1.60          $1.20
   Pro forma                       1.94             1.56           1.20



The fair value of options  granted  (which is amortized to expense over the
option vesting period in determining the pro forma impact),  is estimated on the
date of grant using the  Black-Scholes  multiple  option-pricing  model with the
following weighted average assumptions:




                                          1997         1996           1995
                                                                  
                                  ---------------------------------------------
Expected life of option                 2-7 years    1-6 years       1-6 years
Risk-free interest rate                  5.7-6.6%      5-6.5%        5.5-6.9%
Expected volatility of stock               40%         30-50%         30-50%
Expected dividend yield                    None         None           None



The actual  value of the  options  will  depend on the excess of the market
price of the  shares  over the  exercise  price  on the  date  the  options  are
exercised,  and may vary  significantly from the theoretical values estimated by
the Black-Scholes model.

A summary of the status of the Company's  three fixed stock option plans as
of December  31,  1997,  1996 and 1995,  and changes  during the years ending on
those dates is presented below.





                                        1997                                      1996                               1995
                                     --------------------------------------------------------------------------------------
                                                   Weighted-Average            Weighted-Average            Weighted-Average
                                                     Exercise                    Exercise                    Exercise
FIXED OPTIONS                        Shares            Price          Shares       Price          Shares       Price
                                                                                               
                                     --------------------------------------------------------------------------------------
Outstanding at beginning of year          838,315     $25.12          723,240    $ 20.60          931,960    $ 15.95
Granted                                   301,150     45.56           320,825      39.70           77,000      34.37
Exercised                               (264,795)     17.60          (65,700)      19.95        (272,080)       8.48
Forfeited/canceled                       (23,825)     35.12         (140,050)      37.59         (13,640)      22.57
                                     -------------               -------------               -------------
Outstanding at end of year                850,845     34.42           838,315      25.12          723,240      20.60
                                     =============               =============               =============

Options exercisable at year end           320,645                     377,760                     282,980
Weighted-average fair value of
  options granted during the year          $19.82                      $13.14                      $13.39





The  following  table  summarizes  information  about fixed  stock  options
outstanding at December 31, 1997:




                                     Options Outstanding                                    Options Exercisable
                     ---------------------------------------------------------  ---------------------------------------
                           Number         Weighted-Average                                Number       
     Range of          Outstanding at        Remaining         Weighted-Average         Exercisable    Weighted-Average
  Exercise Prices         12/31/97        Contractual Life      Exercise Price          at 12/31/97     Exercise Price
                                                                                              
- -----------------------------------------------------------------------------------------------------------------------
 $   6.50 - 21.50           190,900             5.2                 $ 14.24                 173,400         $ 13.76
    26.75 - 31.50           182,670             7.6                   29.58                  47,970           29.90
    32.50 - 34.00           171,500             8.4                   33.66                  45,400           33.11
   41.625 - 50.50           235,275             8.9                   48.34                  53,875           46.98
            57.00            70,500             9.9                   57.00
                     ===============                                                  ==============
     6.50 - 57.00           850,845             7.8                   34.42                 320,645           24.50
                     ===============                                                  ==============



     11. ACQUISITION

     Effective January 1, 1996, the Company and its wholly owned subsidiary, ESI
Canada,  Inc.,  acquired  certain  assets,  software  licenses  and  the  claims
processing business of Eclipse Claims Services,  Inc.  ("Eclipse") for $940,000.
Eclipse was a processor of Canadian  pharmacy  claims and was owned by Manulife,
the   Prudential    Insurance    Company   of   America   Canadian    Operations
("Prudential-Canada"),  Aetna Life Insurance Company of Canada  ("Aetna-Canada")
and Metropolitan Life Insurance Company.  The acquisition has been accounted for
under the purchase  method of accounting.  The purchase price has been allocated
to the assets  acquired,  based on their  estimated  fair  values at the date of
acquisition.  Effective  January 1, 1996, and in connection with the acquisition
of certain  assets and  software  licenses of Eclipse  described  above,  and in
addition to the agreement between the Company and Manulife, ESI Canada signed an
agreement with each of Aetna and Prudential-Canada, pursuant to which ESI Canada
will  provide  electronic  drug  claim  processing  and other  pharmacy  benefit
management  services  in  Canada  for a  period  of  five  years.  Subsequently,
Prudential-Canada was acquired by London Life Insurance Company ("London"),  and
London in turn was acquired by Great-West Lifeco.  Inc. In addition,  ESI Canada
is providing services to Crown Life Insurance Company.

     12. QUARTERLY FINANCIAL DATA (UNAUDITED)

     The following table  summarizes the quarterly  financial data for the years
ended December 31, 1997 and 1996:



                                                           Selling,
                                Net          Cost of       General &       Operating      Net        Earnings Per Share
  (IN THOUSANDS)              Revenues       Revenues    Administrative     Income      Income       Basic      Diluted
                                                                                               
- -------------------------------------------------------------------------------------------------------------------------
1997
March 31, 1997                   $261,990     $237,298        $13,298        $11,394      $7,641      $0.47        $0.46
June 30, 1997                     300,515      274,906         13,733         11,876       8,131       0.50         0.50
September 30, 1997                319,937      291,590         15,758         12,589       8,613       0.52         0.52
December 31, 1997                 348,192      315,373         19,828         12,991       9,044       0.55         0.54
- -------------------------------------------------------------------------------------------------------------------------
1996
March 31, 1996                   $168,389     $148,985        $10,387        $ 9,017      $5,580      $0.37        $0.36
June 30, 1996                     184,724      162,797         12,255          9,672       6,403       0.40         0.39
September 30, 1996                194,324      172,316         11,668         10,340       7,014       0.42         0.42
December 31, 1996                 226,178      200,784         14,793         10,601       7,151       0.44         0.43





     13. SUBSEQUENT EVENT - POTENTIAL ACQUISITION

     On  February  20,  1998  the  Company  announced  that  it had  executed  a
definitive  agreement  to purchase  ValueRx,  the PBM  business of  Columbia/HCA
Healthcare Corporation  ("Columbia").  Under terms of the agreement, the Company
will pay cash in the amount of $445 million for the stock of Value Health,  Inc.
and  Managed  Prescription  Network,  Inc.,  the sole assets of which at closing
shall be various subsidiaries each now or formerly conducting business as a PBM,
including   ValueRx   Pharmacy   Program,   Inc.  The  Company  expects  to  use
approximately  $100  million of its own cash and  finance the  remainder  of the
purchase price through a five year bank facility. In 1997 the unaudited combined
revenue of the two companies was in excess of $2.7 billion. The acquisition will
be accounted  for as a purchase and is subject to customary  closing  conditions
including  required  governmental  approvals and consummation and funding of the
bank credit facility.  The Company anticipates the transaction will close in the
second quarter of 1998.


ITEM 9 - CHANGES IN AND  DISAGREEMENTS  WITH  ACCOUNTANTS ON ACCOUNTING AND
FINANCIAL DISCLOSURE

         None.


                                    PART III


ITEM 10 - DIRECTORS AND EXECUTIVE OFFICERS OF THE REGISTRANT

     The  information  required by this item will be  incorporated  by reference
from the Company's  definitive  Proxy  Statement for its 1998 Annual  Meeting of
Stockholders  to be filed  pursuant to  Regulation  14A (the "Proxy  Statement")
under the heading "I.  Election of  Directors";  provided that the  Compensation
Committee Report on Executive  Compensation and the performance  graph contained
therein shall not be deemed to be incorporated herein; and further provided that
the information  regarding the Company's executive officers required by Item 401
of Regulation S-K has been included in Part I of this report.


ITEM 11 - EXECUTIVE COMPENSATION

     The  information  required by this item will be  incorporated  by reference
from  the  Proxy  Statement  under  the  headings   "Directors'   Compensation,"
"Compensation  Committee  Interlocks and Insider  Participation"  and "Executive
Compensation."


ITEM 12 - SECURITY OWNERSHIP OF CERTAIN BENEFICIAL OWNERS AND MANAGEMENT

     The  information  required by this item will be  incorporated  by reference
from the Proxy  Statement  under the  headings  "Security  Ownership  of Certain
Beneficial Owners and Management."


ITEM 13 - CERTAIN RELATIONSHIPS AND RELATED TRANSACTIONS

     The  information  required by this item will be  incorporated  by reference
from the Proxy Statement under the heading  "Certain  Relationships  and Related
Transactions."




                                     PART IV

ITEM 14 - EXHIBITS, FINANCIAL STATEMENT SCHEDULES AND REPORTS ON FORM 8-K

(a)  Documents filed as part of this Report

     (1)  Financial Statements

     The  following  report  of  independent  accountants  and the  consolidated
financial  statements  of the Company are  contained  in this Report on the page
indicated

                                               Page No. In
                                                Form 10-K

Report of Independent Accountants                25

Consolidated Balance Sheet as of
  December 31, 1997 and 1996                     26

Consolidated Statement of Operations
  for the years ended December 31, 1997,
  1996 and 1995                                  27

Consolidated Statement of Changes in
  Stockholders' Equity for the years ended
  December 31, 1997, 1996 and 1995               28

Consolidated Statement of Cash Flows for
  the years ended December 31, 1997,
  1996 and 1995                                  29

Notes to Consolidated Financial Statements       30

     (2) The following  financial statement schedule is contained in this Report
on the page indicated.

                                                      Page No. In
Financial Statement Schedule:                          Form 10-K

  VIII.  Valuation and Qualifying Accounts
         and Reserves for the years ended
         December 31, 1997, 1996 and 1995                 45

     All other  schedules  are omitted  because they are not  applicable  or the
required  information is shown in the consolidated  financial  statements or the
notes thereto.

     (3)  List of Exhibits

                  See Index to Exhibits on pages 46 - 53.

(b)  Reports on Form 8-K

     On  November  4,  1997,  the  Company  filed a  Current  Report on Form 8-K
regarding a press release issued on behalf of the Company.



                                                    SIGNATURES

     Pursuant  to the  requirements  of  Section  13 or 15(d) of the  Securities
Exchange Act of 1934, the registrant has duly caused this report to be signed on
its behalf by the undersigned thereunto duly authorized.

                              EXPRESS SCRIPTS, INC.


March 26, 1998                By:/s/ Barrett A. Toan
                                 Barrett A. Toan, President
                                 and Chief Executive Officer

     Pursuant to the  requirements of the Securities  Exchange Act of 1934, this
report  has  been  signed  below  by the  following  persons  on  behalf  of the
registrant and in the capacities and on the dates indicated.

SIGNATURE                     TITLE                           DATE


/s/ Barrett A. Toan        President,                     March 26, 1998
Barrett A. Toan            Chief Executive
                           Officer and Director

/s/ George Paz             Senior Vice President and      March 25, 1998
George Paz                 Chief Financial Officer

/s/ Joseph W. Plum         Vice President and             March 25, 1998
Joseph W. Plum             Chief Accounting Officer

/s/ Howard I. Atkins       Director                       March 18, 1998
Howard I. Atkins

/s/ Judith E. Campbell     Director                       March 25, 1998
Judith E. Campbell

/s/ Richard M. Kernan, Jr. Director                       March 25, 1998
Richard M. Kernan, Jr.

/s/ Richard A. Norling     Director                       March 25, 1998
Richard A. Norling

/s/ Frederick J. Sievert   Director                       March 25, 1998
Frederick J. Sievert

/s/ Stephen N. Steinig    Director                       March 25, 1998
Stephen N. Steinig

/s/ Seymour Sternberg      Director                       March 25, 1998
Seymour Sternberg

/s/ Howard L. Waltman      Director                       March 25, 1998
Howard L. Waltman

/s/ Norman Zachary         Director                       March 25, 1998
Norman Zachary






                              EXPRESS SCRIPTS, INC.
              Schedule VIII - Valuation and Qualifying Accounts and
                  Reserves Years Ended December 31, 1995, 1996
                                    and 1997


       COL. A            COL. B                      COL. C                   COL. D           COL. E
- ---------------------   ---------          ---------------------------      -----------       ---------
                                                    Additions
                                           ---------------------------
                         Balance            Charges           Charges                           Balance
                            at              to Costs          to Other                          at End
                        Beginning             and                and                              of
    Description         Of Period           Expenses          Accounts       (Deductions)       Period
                                                                                          
- ---------------------   ---------           ---------         --------       ------------      --------  
Allowance for Doubtful
Accounts Receivable

Year Ended 12/31/95     $1,201,161         $1,688,453                         $   615,677      $2,273,937
Year Ended 12/31/96     $2,273,937         $1,456,130                         $1,394,922       $2,335,145
Year Ended 12/31/97     $2,335,145         $3,680,409                         $1,213,991       $4,801,563







                                INDEX TO EXHIBITS
            (Express Scripts, Inc. - Commission File Number 0-20199)



Exhibit
Number         Exhibit

2.1            Stock  Purchase  Agreement by and among  Columbia/HCA  Healthcare
               Corporation,  VH Holdings, Inc., Galen Holdings, Inc. and Express
               Scripts, Inc., dated as of February 19, 1998, and certain related
               Schedules,  incorporated  by  reference to Exhibit No. 2.1 to the
               Company's Current Report on Form 8-K filed March 2, 1998.

3.1            Certificate  of  Incorporation,   incorporated  by  reference  to
               Exhibit No. 3.1 to the Company's  Registration  Statement on Form
               S-1  filed  June  9,  1992  (No.   33-46974)  (the  "Registration
               Statement").

3.2            Certificate of Amendment of the Certificate of  Incorporation  of
               the Company, incorporated by reference to Exhibit No. 10.6 to the
               Company's  Quarterly  Report on Form 10-Q for the quarter  ending
               June 30, 1994.

3.3            Second Amended and Restated Bylaws,  incorporated by reference to
               Exhibit No. 3.3 to the  Company's  Quarterly  Report on Form 10-Q
               for the quarter ending September 30, 1997.

4.1            Form of  Certificate  for Class A Common Stock,  incorporated  by
               reference to Exhibit No. 4.1 to the Registration Statement.

10.1+          Stock Agreement  (Initial Shares) entered into as of December 31,
               1995,  between  the Company and  American  Healthcare  Purchasing
               Partners, L.P., incorporated by reference to Exhibit No. 10.61 to
               the  Company's  Annual  Report on Form  10-K for the year  ending
               1995.

10.2+          Stock Agreement  (Membership  Shares) entered into as of December
               31, 1995, between the Company and American Healthcare  Purchasing
               Partners, L.P., incorporated by reference to Exhibit No. 10.62 to
               the  Company's  Annual  Report on Form  10-K for the year  ending
               1995.

10.3+          Amended  and  Restated  Agreement  entered  into as of March  29,
               1995,  between  the  Company  and  Sanus  Corp.  Health  Systems,
               incorporated  by reference  to Exhibit No. 10.1 to the  Company's
               Annual Report on Form 10-K for the year ending 1995.

10.4+          Form of Amended and Restated  Managed  Prescription  Drug Program
               Agreement entered into as of March 29, 1995,  between the Company
               and each of the  following  parties:  Health  Plus,  Inc.,  Sanus
               Health Plan of New Jersey,  Inc.,  Sanus Texas Health Plan, Inc.,
               Sanus/New  York Life  Health  Plan,  Inc.,  Sanus  Health Plan of
               Illinois,  Inc. and Sanus Health Plan of Greater New York,  Inc.,
               incorporated  by reference  to Exhibit No. 10.2 to the  Company's
               Annual Report on Form 10-K for the year ending 1995.

10.5+          Managed Prescription Drug Program Agreement dated as of May 1,
               1996 by and between the Company and NYLCare Health Plans of
               Maine, Inc., incorporated by reference to Exhibit No. 10.3 to the
               Company's Quarterly Report on Form 10-Q for the quarter ending
               March 31, 1997.

10.6+          Managed Prescription Drug Program Agreement dated as of December
               31, 1995 by and between the Company and WellPath Community Health
               Plan, Inc., incorporated by reference to Exhibit No. 10.2 to the
               Company's Quarterly Report on Form 10-Q for the quarter ending
               March 31, 1997.

10.7+          Form of Amended and Restated Vision Program Sponsor Agreement
               entered into as of March 29, 1995, between the Company and each
               of the following parties: Health Plus, Inc., Sanus Health Plan of
               New Jersey, Inc., Sanus Texas Health Plan, Inc., Sanus/New York
               Life Health Plan, Inc., Sanus Health Plan of Illinois, Inc. and
               Sanus Health Plan of Greater New York, Inc., incorporated by
               reference to Exhibit No. 10.3 to the Company's Annual Report on
               Form 10-K for the year ending 1995.

10.8+          Form of Amended and Restated Infusion Therapy Agreement entered
               into as of March 29, 1995, between the Company and each of the
               following parties: Health Plus, Inc., Sanus Texas Health Plan,
               Inc., Sanus/New York Life Health Plan, Inc., and Sanus Health
               Plan of Illinois, Inc., incorporated by reference to Exhibit No.
               10.4 to the Company's Annual Report on Form 10-K for the year
               ending 1995.

10.9+          Form of Infusion Therapy  Agreement  entered into as of March 29,
               1995,  between  the Company  and each of the  following  parties:
               Sanus  Health Plan of New Jersey,  Inc.  and Sanus Health Plan of
               Greater New York, Inc.,  incorporated by reference to Exhibit No.
               10.5 to the  Company's  Annual  Report  on Form 10-K for the year
               ending 1995.

10.10          First Amendment to Vision Program Sponsor Agreement entered into
               as of September 1, 1995, between the Company and Sanus Health
               Plan of New Jersey, Inc., incorporated by reference to Exhibit
               No. 10.6 to the Company's Annual Report on Form 10-K for the year
               ending 1995.

10.11          First  Amendment  to the  Amended  and  Restated  Vision  Program
               Sponsor  Agreement  entered into as of November 1, 1995,  between
               the Company and Sanus Texas Health Plan,  Inc.,  incorporated  by
               reference to Exhibit No. 10.7 to the  Company's  Annual Report on
               Form 10-K for the year ending 1995.

10.12          Agreement  dated  January 1, 1989,  as amended May 31, 1989,  and
               January 1, 1991,  between the Company and New York Life Insurance
               Company,  incorporated  by  reference to Exhibit No. 10.20 to the
               Registration Statement.

10.13          Third  Amendment  dated as of July  30,  1993,  to the  Agreement
               dated as of January 1, 1989,  by and  between the Company and New
               York Life Insurance Company, incorporated by reference to Exhibit
               No. 10.16 to the Company's  Quarterly Report on Form 10-Q for the
               quarter ending September 30, 1993.

10.14          Amended and Restated Managed  Prescription Drug Program Agreement
               entered into as of September 1, 1995, between the Company and New
               York Life Insurance Company, incorporated by reference to Exhibit
               No.  10.24 to the  Company's  Annual  Report on Form 10-K for the
               year ending 1995.

10.15+         First  Amendment to Amended and Restated  Managed  Prescription
               Drug  Program  Agreement  and Consent to  Assignment  dated as of
               January  1,  1997,  by and  between  the  Company,  New York Life
               Insurance Company and NYLCare Health Plans, Inc., incorporated by
               reference to Exhibit No. 10.1 to the Company's  Quarterly  Report
               on Form 10-Q for the quarter ending March 31, 1997.

10.16          Quota-Share Reinsurance Agreement executed as of August 15, 1994,
               between New York Life Insurance Company and Great Plains
               Reinsurance Company, incorporated by reference to Exhibit 10.1 to
               the Company's Quarterly Report on Form 10-Q for the quarter
               ending September 30, 1994.

10.17          Amendment No. 1 to Quota-Share Reinsurance Agreement dated as of
               September 13, 1994, between New York Life Insurance Company and
               Great Plains Reinsurance Company, incorporated by reference to
               Exhibit 10.2 to the Company's Quarterly Report on Form 10-Q for
               the quarter ending September 30, 1994.

10.18          Joint Research  Agreement dated June 28, 1994, by and between the
               Company,  Sanus Corp.  Health  Systems and Schering  Corporation,
               incorporated  by  reference  to  Exhibit  10.4  to the  Company's
               Quarterly  Report on Form 10-Q for the quarter  ending  September
               30, 1994.

10.19          Amendment  Number  Four to the  Home  Infusion  Therapy  Services
               Agreement  made and entered into as of November 15, 1993,  by and
               between  IVTx of Houston,  Inc. and Sanus  Preferred  Physicians,
               Inc.,  incorporated  by  reference  to Exhibit  No.  10.36 to the
               Company's Form 10-K for the year ending 1993.

10.20          Letter  Agreement  dated April 1, 1992,  between IVTx of Houston,
               Inc.  and  Sanus  Preferred  Physicians,  Inc.,  incorporated  by
               reference to Exhibit No. 10.13 to the Registration Statement.

10.21          Affiliate Provider  Participation  Agreement dated April 1, 1992,
               as amended  November 25, 1992,  between IVTx of Dallas,  Inc. and
               Sanus Preferred  Physicians,  Inc.,  incorporated by reference to
               Exhibit No. 10.28 to the Company's Annual Report on Form 10-K for
               the year ending 1992.

10.22          Amendment  Two to  the  Sanus  Preferred  Physicians,  Inc.  Home
               Infusion  Therapy  Services  Agreement  entered into as of May 1,
               1993,   between  IVTx  of  Dallas,   Inc.  and  Sanus   Preferred
               Physicians,  Inc.,  incorporated by reference to Exhibit No. 10.2
               to the Company's Form 10-Q for the quarter ending June 30, 1993.

10.23          Amendment Three to the Home Infusion Therapy  Services  Agreement
               entered into as of June 1, 1993, between IVTx of Dallas, Inc. and
               Sanus Preferred  Physicians,  Inc.,  incorporated by reference to
               Exhibit No. 10.3 to the Company's  Quarterly  Report on Form 10-Q
               for the quarter ending June 30, 1993.

10.24          Amendment Four to the Home Infusion  Therapy  Services  Agreement
               entered  into as of July 1, 1993,  by and between IVTx of Dallas,
               Inc.  and  Sanus  Preferred  Physicians,  Inc.,  incorporated  by
               reference to Exhibit No. 10.9 to the Company's  Quarterly  Report
               on Form 10-Q for the quarter ending September 30, 1993.

10.25          Home  Infusion  Therapy  Services  Agreement  dated May 1,  1991,
               between Sanus/Passport  Preferred Services, Inc. and the Company,
               incorporated   by   reference   to  Exhibit  No.   10.19  to  the
               Registration Statement.

10.26          Amendment One to the Home  Infusion  Therapy  Services  Agreement
               entered  into as of July 1, 1993,  by and between the Company and
               Sanus/Passport   Preferred   Services,   Inc.,   incorporated  by
               reference to Exhibit No. 10.3 to the Company's  Quarterly  Report
               on Form 10-Q for the quarter ending September 30, 1993.

10.27          Amendment Two to the Home Infusion Therapy Services Agreement
               entered into as of July 1, 1993, by and between the Company and
               Sanus/Passport Preferred Services, Inc., incorporated by
               reference to Exhibit No. 10.4 to the Company's Quarterly Report
               on Form 10-Q for the quarter ending September 30, 1993.

10.28          Amendment Four to the Home Infusion Therapy Services Agreement
               entered into as of July 1, 1993, by and between the Company and
               Sanus/Passport Preferred Services, Inc., incorporated by
               reference to Exhibit No. 10.5 to the Company's Quarterly Report
               on Form 10-Q for the quarter ending September 30, 1993.

10.29          Agreement  dated May 7, 1992,  between  the  Company and New York
               Life Insurance Company,  incorporated by reference to Exhibit No.
               10.26 to the Registration Statement.

10.30          Affiliate  Provider  Participation  Agreement  dated September 1,
               1991,  between IVTx, Inc. and Sanus Preferred  Physicians,  Inc.,
               incorporated   by   reference   to  Exhibit  No.   10.12  to  the
               Registration Statement

10.31          Amendment   dated  January   1993,  to  the  Affiliate   Provider
               Participation Agreement dated September 1, 1991, between IVTx and
               Sanus  Preferred  Physicians,  Inc.  incorporated by reference to
               Exhibit No. 10.22 to the Company's Annual Report on Form 10-K for
               the year ending 1992.

10.32          Amendment  Three to the Sanus  Preferred  Physicians,  Inc.  Home
               Infusion  Therapy  Services  Agreement  entered into as of May 1,
               1993,   between  IVTx  of  Dallas,   Inc.  and  Sanus   Preferred
               Physicians,  Inc.,  incorporated by reference to Exhibit No. 10.8
               to the  Company's  Quarterly  Report on Form 10-Q for the quarter
               ending June 30, 1993.

10.33          Lease Agreement dated March 3, 1992, between Riverport,  Inc. and
               Douglas Development  Company--Irvine Partnership in commendam and
               the  Company,  incorporated  by reference to Exhibit No. 10.21 to
               the Registration Statement.

10.34          First Amendment to Lease dated as of December 29, 1992,  between
               Sverdrup/MDRC  Joint  Venture and the  Company,  incorporated  by
               reference to Exhibit No. 10.13 to the Company's  Quarterly Report
               on Form 10-Q for the quarter ending June 30, 1993.

10.35          Second  Amendment  to  Lease  dated as of May 28,  1993,  between
               Sverdrup/MDRC  Joint  Venture and the  Company,  incorporated  by
               reference to Exhibit No. 10.14 to the Company's  Quarterly Report
               on Form 10-Q for the quarter ending June 30, 1993.

10.36          Third Amendment to Lease entered into as of October 15, 1993, by
               and between Sverdrup/MDRC Joint Venture and the Company,
               incorporated by reference to Exhibit No. 10.69 to the Company's
               Annual Report on Form 10-K for the year ending 1993.

10.37          Fourth  Amendment  to Lease  dated as of March 24,  1994,  by and
               between Sverdrup/MDRC Joint Venture and the Company, incorporated
               by reference to Exhibit No. 10.70 to the Company's  Annual Report
               on Form 10-K for the year ending 1993.

10.38          Fifth  Amendment  to Lease made and entered  into June 30,  1994,
               between Sverdrup/MDRC Joint Venture and the Company, incorporated
               by reference to Exhibit 10.1 to the Company's Quarterly Report on
               Form 10-Q for the quarter ending June 30, 1994.

10.39          Sixth Amendment to Lease made and entered into January 31, 1995,
               between Sverdrup/MDRC Joint Venture and the Company, incorporated
               by reference to Exhibit No. 10.70 to the Company's Annual Report
               on Form 10-K for the year ending 1994.

10.40          Guaranty  Agreement  dated  March 3, 1992,  between  Sanus  Corp.
               Health Systems, Inc. and Riverport,  Inc. and Douglas Development
               Company--Irvine   Partnership  in  commendam,   incorporated   by
               reference to Exhibit No. 10.22 to the Registration Statement.

10.41          Confirmation of Guaranty entered into as of June 17, 1993,
               between Sverdrup/MDRC Joint Venture and NYLIFE HealthCare
               Management, Inc., incorporated by reference to Exhibit No. 10.15
               to the Company's Quarterly Report on Form 10-Q for the quarter
               ending June 30, 1993.

10.42          Release of Guaranty of NYLIFE HealthCare Management, Inc.,
               Guarantor of the Company's Obligations under its Lease with
               Riverport, Inc. and Douglas Development Company, dated May 8,
               1996, incorporated by reference to Exhibit No. 10.2 to the
               Company's Quarterly Report on Form 10-Q for the quarter ending
               June 30, 1996.

10.43          Single-Tenant  Lease-Net  entered  into  as  of  June  30,  1993,
               between James M. Chamberlain, Trustee of Chamberlain Family Trust
               dated  September  21,  1979,  and the  Company,  incorporated  by
               reference to Exhibit No. 10.16 to the Company's Form 10-Q for the
               quarter ending June 30, 1993.

10.44          First  Amendment to  Single-Tenant  Lease-Net  entered into as of
               November 12, 1993, by and between James M.  Chamberlain,  Trustee
               of Chamberlain  Family Trust,  and the Company,  incorporated  by
               reference to Exhibit No. 10.74 to the Company's  Annual Report on
               Form 10-K for the year ending 1993.

10.45          Guaranty Agreement entered into as of June 30, 1993, between
               NYLIFE HealthCare Management, Inc. and James M. Chamberlain,
               Trustee of Chamberlain Family Trust dated September 21, 1979,
               incorporated by reference to Exhibit No. 10.17 to the Company's
               Quarterly Report on Form 10-Q for the quarter ending June 30,
               1993.

10.46          Release  of  Guaranty  of  NYLIFE  HealthCare  Management,  Inc.,
               Guarantor  of the  Company's  Obligations  under its  Lease  with
               Kenneth  H. Dart , Trustee  of Trust B of Dart  Family  Revocable
               Estate Trust,  dated June 21, 1996,  incorporated by reference to
               Exhibit No. 10.3 to the Company's  Quarterly  Report on Form 10-Q
               for the quarter ending June 30, 1996.

10.47          Earth City Industrial  Office/Warehouse  Lease Agreement dated as
               of  August  19,  1996,  by and  between  the  Company  and  Louis
               Siegfried  Corporation,  incorporated by reference to Exhibit No.
               10.1 to the  Company's  Quarterly  Report  on Form  10-Q  for the
               quarter ending September 30, 1996.

10.48          Revolving  Loan  Agreement  dated  as of May  21,  1993,  between
               Mercantile Bank of St. Louis N. A. and the Company,  incorporated
               by  reference  to Exhibit  No.  10.1 to the  Company's  Quarterly
               Report on Form 10-Q for the quarter ending June 30, 1993.

10.49          Amendment to Revolving Loan Agreement made as of May 31, 1994,
               between the Company and Mercantile Bank of St. Louis N.A.,
               incorporated by reference to Exhibit No. 10.5 to the Company's
               Quarterly Report on Form 10-Q for the quarter ending June 30,
               1994.

10.50          Second  Amendment to Revolving  Loan Agreement made as of May 30,
               1995,  between the Company and Mercantile Bank of St. Louis N.A.,
               incorporated  by  reference  to  Exhibit  10.1  to the  Company's
               Quarterly  Report on Form 10-Q for the  quarter  ending  June 30,
               1995.

10.51          Third  Amendment to Revolving  Loan  Agreement made as of May 29,
               1996, by and between the Company and Mercantile Bank of St. Louis
               National  Association,  incorporated  by reference to Exhibit No.
               10.1 to the  Company's  Quarterly  Report  on Form  10-Q  for the
               quarter ending June 30, 1996.

10.52          Fourth Amendment to Revolving Loan Agreement made as of May 29,
               1997, by and between the Company and Mercantile Bank National
               Association, formerly known as Mercantile Bank of St. Louis
               National Association, incorporated by reference to Exhibit No.
               10.1 to the Company's Quarterly Report on Form 10-Q for the
               quarter ending June 30, 1997.

10.53+         Agreement dated October 9, 1992, among the Company,  FHP, Inc.,
               FHP of Utah,  Inc., FHP of New Mexico,  Inc. and Employees Choice
               Health Option,  incorporated by reference to Exhibit No. 10.42 to
               the  Company's  Annual  Report on Form  10-K for the year  ending
               1992.

10.54          Joinder  Agreement  entered into as of December 31, 1994,  by and
               between the Company and FHP of Colorado,  Inc.,  incorporated  by
               reference to Exhibit No. 10.84 to the Company's  Annual Report on
               Form 10-K for the year ending 1994.

10.55          Joinder  Agreement  entered into as of December 31, 1994,  by and
               between the Company and TakeCare Health Plan, Inc.,  incorporated
               by reference to Exhibit No. 10.86 to the Company's  Annual Report
               on Form 10-K for the year ending 1994.

10.56          Joinder  Agreement  entered into as of December 31, 1994,  by and
               between   the  Company  and   TakeCare   of   California,   Inc.,
               incorporated  by reference to Exhibit No. 10.86 to the  Company's
               Annual Report on Form 10-K for the year ending 1994.

10.57          Joinder  Agreement  entered into as of December 31, 1994,  by and
               between the Company and TakeCare  Health Plan of Illinois,  Inc.,
               incorporated  by reference to Exhibit No. 10.87 to the  Company's
               Annual Report on Form 10-K for the year ending 1994.

10.58          Joinder  Agreement  entered into as of December 31, 1994,  by and
               between  the  Company and  TakeCare  Health  Plan of Ohio,  Inc.,
               incorporated  by reference to Exhibit No. 10.88 to the  Company's
               Annual Report on Form 10-K for the year ending 1994.

10.59          Joinder Agreement and Amendment (Great States Workers'
               Compensation Plans) entered into as of December 1, 1995, among
               the Company, Great States Insurance Company, and Great States
               Administrators, Inc., incorporated by reference to Exhibit No.
               10.59 to the Company's Annual Report on Form 10-K for the year
               ending 1995.

10.60#         Express Scripts, Inc. 1992 Stock Option Plan, incorporated by 
               reference to Exhibit No.10.23 to the Registration Statement.

10.61#         Express Scripts, Inc. Stock Option Plan for Outside Directors, 
               incorporated by reference to Exhibit No. 10.24 to the 
               Registration Statement.

10.62#         Express Scripts, Inc. 1994 Stock Option Plan, incorporated by 
               reference to Exhibit No. 10.4 to the Company's Quarterly Report 
               on Form 10-Q for the quarter ending June 30, 1994.

10.63#         Amended and Restated Express Scripts, Inc. 1992 Employee Stock 
               Option Plan, incorporated byreference to Exhibit No. 10.78 to 
               the Company's Annual Report on Form 10-K for the year 
               ending 1994.

10.64#         Amended and Restated Express Scripts, Inc. Stock Option Plan for
               Outside Directors, incorporated by reference to Exhibit No. 10.79
               to the Company's Annual Report on Form 10-K for the year ending 
               1994.

10.65#         First Amendment to Express Scripts, Inc. Amended and Restated 
               1992 Stock Option Plan for Outside Directors incorporated by 
               reference to Exhibit A to the Company's Proxy Statement
               dated April 9, 1996.

10.66#         Amended and Restated Express Scripts, Inc. 1994 Stock Option 
               Plan incorporated by reference to Exhibit No. 10.80 to the 
               Company's Annual Report on Form 10-K for the year
               ending 1994.

10.67#         First Amendment to Express  Scripts,  Inc. Amended and Restated
               1994 Stock Option Plan  incorporated by reference to Exhibit A to
               the Company's Proxy Statement dated April 16, 1997.

10.68#         Employment  Agreement dated April 30, 1992, between the Company
               and Barrett A. Toan (including form of Non-Qualified Stock Option
               Agreement), incorporated by reference to Exhibit No. 10.25 to the
               Registration Statement.

10.69#         Letter Agreement amending  Employment  Agreement dated February
               28, 1996,  from the Company to Barrett A. Toan,  incorporated  by
               reference to Exhibit No. 10.51 to the Company's  Annual Report on
               Form 10-K for the year ending 1995.

10.70#*        Form of  Severance  Agreement  dated as of January  27,  1998,
               between the Company and each of the following individuals: Stuart
               L.  Bascomb,  Thomas  M.  Boudreau,  Robert  W.  Davis,  Linda L.
               Logsdon, David A. Lowenberg, and George Paz.

21.1*          List of Subsidiaries.

23.1*          Consent of Price Waterhouse LLP.

27.1*          Financial  Data  Schedule  (provided for the  information  of the
               U.S. Securities and Exchange Commission only).



*    Filed herein.
+   Confidential treatment granted for certain portions of these exhibits.
#    Management contract or compensatory plan or arrangement.