AMENDMENT NO. 1 TO MANAGEMENT AGREEMENT

                                      AMONG

                            INTEGRAMED AMERICA, INC.

                                       AND

                        MPD MEDICAL ASSOCIATES (MA), P.C.

                                       AND

                             PATRICIA MCSHANE, M.D.


         THIS AMENDMENT NO. 1 TO MANAGEMENT AGREEMENT ("Amendment No. 1"),
is dated as of  November  18,  1998 by and among  IntegraMed  America,  Inc.,  a
Delaware corporation, with its principal place of business at One Manhattanville
Road, Purchase,  New York 10577 ("Management  Company"),  MPD Medical Associates
(MA), P.C., a Massachusetts  professional corporation,  with its principal place
of business at Deaconess-Waltham  Hospital, Hope Avenue, Waltham,  Massachusetts
02254 ("PC") and Patricia  McShane,  MD, the sole shareholder of PC, residing at
124 Washington Street,  Wellesley,  Massachusetts 02181 (hereinafter referred to
as "McShane" or "Shareholder").

                                    RECITALS:

         Management Company and PC entered into a management  agreement dated as
of October 1, 1997 (the  "Management  Agreement")  pursuant to which  Management
Company agreed to provide certain management and administrative services;

         Management  Company is willing  to grant to each of  McShane,  Isaac Z.
Glatstein,  MD and Samuel  Pang,  MD,  physician-employees  of PC,  warrants  to
acquire shares of Management Company's Common Stock, based on McShane causing PC
to agree to this amendment so as to extend the term from 10 years to 25 years;

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         PC, based on McShane's  approval,  is willing to extend the  Management
Agreement for fifteen (15) years so as to expire twenty-five (25) years from the
Effective Date; and

         Management  Company and PC desire to, in addition to extending the term
of the Management Agreement, amend other provisions thereof.

         NOW THEREFORE,  in consideration of the mutual covenants and agreements
herein contained and other good and valuable  consideration,  the parties hereto
agree as follows:

         1. Section 6.3.3 of the  Management  Agreement is hereby deleted in its
entirety and the following hereby substituted therefor, effective July 1, 1998:

         "6.3.3 Commencing July 1, 1998, the outstanding  Advances owed by PC to
Management  Company from 1996 in the amount of $106,372.00  (One Hundred and Six
Thousand Three-Hundred and Seventy-Two Dollars) (the "Debt") will be repaid from
PDE available to PC in excess of the current $595,000 (Five-Hundred  Ninety-Five
Thousand Dollars) aggregate salary draw of McShane, Samuel Pang, MD ("Pang") and
Isaac  Glatstein,  MD  ("Glatstein")  (the aggregate  draw of McShane,  Pang and
Glatstein is referred to as "Threshold PDE" and McShane,  Pang and Glatstein are
jointly referred to as  "Physicians").  PDE in excess of PC's Threshold PDE will
be distributed 50% to PC as additional PDE for Physicians,  as determined by PC,
and 50% to Management Company as payment of the Debt.

         2. Section 7.2 of the  Management  Agreement  is hereby  deleted in its
entirety and the following hereby substituted therefor, effective July 1, 1998:

         "7.2  PDE shall be  allocated  between  Management  Company  and PC, as
follows:

                  7.2.1    PDE between  $0.00 (zero  dollars)  and $2.5  million
                           shall  be  allocated  forty  percent  (40%) to PC and
                           sixty percent (60%) to Management Company.


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                  7.2.1    PDE in  excess  of $2.5  million  shall be  allocated
                           seventy-five  percent  (75%)  to PC  and  twenty-five
                           percent (25%) to Management Company.

         3. Section 7.3 of the  Management  Agreement  is hereby  deleted in its
entirety and the following hereby substituted therefor, effective July 1, 1998:

         "7.3  Management  Company shall provide  certain funding to PC, for the
purpose of Physician draws against PDE, as follows:

                  7.3.1  During  the  period  July 1,  1998 to  June  30,  2002,
Management Company shall make Advances, as necessary, pursuant to Section 6.3 of
this Agreement, to enable PC to fund bi-weekly draws against PDE for (i) McShane
based on an aggregate  annualized  salary of not less than $110,  000, (ii) Pang
based on an  aggregate  annualized  salary of not less than  $110,000  and (iii)
Glatstein based on an aggregate annualized salary of not less than $110,000,  so
long as each such Physician shall be employed by PC.

                  7.3.2  Commencing  July 1, 2002  Management  Company  will not
provide any Advances to PC for the purpose of Physician draws against PDE."

         4. A new Section 7.4 is added to the Management Agreement as follows:

                  "7.4 Dan Tulchinsky,  MD  ("Tulchinsky") , though eligible for
draws against PDE, will not be eligible to share in any excess PDE.  Tulchinsky,
effective  July 1,  1998,  will  be  entitled  to a  salary  draw  of  $125,000.
Additionally, based on specific Revenue-based milestones, Dr. Tulchinsky will be
eligible for an additional $50,000 annually,  payable in $10,000 increments,  as
more fully set forth in Tulchinsky's employment agreement with PC."

         5. A new Section 7.5 is added to the Management Agreement as follows:


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                  "7.5     PC INCENTIVES.

                           7.5.1    Physicians   will  be  given  five  (5)-year
warrants (the  "Warrants")  to purchase  shares of Management  Company's  Common
Stock in accordance with the terms and provisions of the Warrants.

                           7.5.2    McShane  agrees that in the event PC retains
a full-time Medical Director who commences  employment with PC on or before July
1, 1999 ("Medical  Director  Milestone") and PC achieves PDE of $2.5 million for
PC's 1998 fiscal year ("PDE Milestone") or as an alternative, PC achieves PDE of
either, at least (A) $625,000 for the 4th quarter of 1998,  $637,500 for the 1st
quarter of 1999 and $650,000 for the 2nd quarter  1999  ("First  Substitute  PDE
Milestone")  or  (B)   $1,912,500  in  the  aggregate  for  the   aforementioned
three-quarter  period ("Second  Substitute PDE  Milestone"),  McShane will grant
equity  positions  in PC to (i) the Medical  Director  equivalent  to 20%,  (ii)
Glatstein  equivalent  to 10% and (iii) Pang  equivalent  to 10%.  McShane  will
become a 60% equity owner as a result of such grants.  Thereafter,  in the event
the Medical  Director  Milestone and either the PDE Milestone,  First Substitute
PDE Milestone or Second Substitute PDE Milestone are achieved,  on July 1, 2000,
July 1, 2001 and July 1, 2002, an additional  3.33% of McShane's equity interest
in PC shall be  granted to each of the  Medical  Director,  Glatstein  and Pang.
Effective,  July 1,  2002,  McShane  will own a 30% equity  interest  in PC, the
Medical  Director will own a 30% equity interest in PC, Glatstein will own a 20%
equity  interest  in PC and Pang will own a 20% equity  interest  in PC provided
that PC continues to achieve annual total PDE of $ 2.5 million or above."

                           7.5.3    The Medical Director will be eligible for an
initial 20% equity interest in PC irrespective of Glatstein and Pang.

                           7.5.4    In the event that the PC achieves either the
PDE  Milestone,   First  Substitute  PDE  Milestone  or  Second  Substitute  PDE
Milestone,  yet a  Medical  Director  mutually  acceptable  to the  PC  and  the
Management Company has not been hired, if both the PC and the Management Company
have used their reasonable best efforts in the search for a Medical Director,

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the Medical Director Milestone requirement referred to in 7.5.2 and 7.5.3 may be
waived upon mutual agreement of both the PC and the Management Company.

         6. The first  sentence of Section 8.1 of the  Management  Agreement  is
deleted in its entirety and the following substituted therefor:

         "8.1 The term of this Agreement shall begin October 1, 1997 ("Effective
Date") and shall expire  twenty-five  (25) years after such date unless  earlier
terminated pursuant to Article 9 below."

         7. All other  provisions  of the  Management  Agreement not in conflict
with this Amendment No. 1 remain in full force and effect.

         8. This  Amendment  No. 1 may be  executed  in any  number of  separate
counterparts,  each of  which  shall be  deemed  an  original,  but all of which
together shall constitute one and the same instrument.

         IN WITNESS WHEREOF, the parties have signed this Amendment No. 1 as the
date first above written.


INTEGRAMED AMERICA, INC.                          SHAREHOLDER:

By:/s/Gerardo Canet                               /s/Patricia McShane
   ------------------------                       ------------------------
   Gerardo Canet, President                          Patricia McShane, MD


MPD MEDICAL ASSOCIATES (MA), P.C.

By:  /s/Patricia
        -----------------------------
        Patricia McShane, MD, President

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