MANAGEMENT AGREEMENT

                                      AMONG

                            INTEGRAMED AMERICA, INC.

                                       AND

              REPRODUCTIVE ENDOCRINE & FERTILITY CONSULTANTS, P.A.

                                       AND

                MIDWEST FERTILITY FOUNDATIONS & LABORATORY, INC.





         THIS MANAGEMENT  AGREEMENT  ("Agreement"),  dated as of May 1, 1999, by
and among IntegraMed America,  Inc., a Delaware corporation,  with its principal
place  of  business  at  One  Manhattanville  Road,  Purchase,  New  York  10577
("Management Company"),  Reproductive Endocrine & Fertility Consultants, P.A., a
Kansas professional  association,  having its principal place of business at Two
Brush  Creek,  Suite 500,  Kansas  City,  Missouri  64112  ("PA"),  and  Midwest
Fertility  Foundations  &  Laboratory,  Inc., a Kansas  corporation,  having its
principal place of business at Two Brush Creek, Suite 500, Kansas City, Missouri
64112  ("Midwest").  PA and  Midwest  are  collectively  referred  to  herein as
"Providers" and PA, Midwest and Management Company are collectively  referred to
as "Parties" and individually, as a "Party."

                                    RECITALS:

         PA  is  a  medical  practice  ("Medical   Practice")   specializing  in
gynecological  services,   treatment  of  human  infertility   encompassing  the
provision of in vitro  fertilization  and other assisted  reproductive  services
("Infertility Services").

         Midwest is a licensed clinical reference laboratory (the "Lab").

         Management  Company is in the  business  of owning  certain  assets and
providing  management and  administrative  services  ("Management  Services") to
medical  practices  specializing in the provision of Infertility  Services,  and
furnishing  such medical  practices  with the necessary  facilities,  equipment,
personnel, supplies and support staff.

         This  Agreement  is made  with  reference  to that  certain  management
agreement  by and among the  Parties  dated  November  1,  1995,  as  amended by
agreements  dated  May 22,  1997 and July 1,  1998,  and  that  certain  interim
agreement  by and among the  Parties  dated  January  25,  1999,  as  amended by
agreement dated March 26, 1999 (collectively,  "Former Agreements").  All Former
Agreements,  upon execution of this Agreement are canceled, null, void and of no
further  legal  effect.  Any  obligation  of a  Party  contained  in the  Former
Agreements not specifically set forth herein is deemed canceled.

         Management  Company  will  provide  Management  Services and the use of
certain  Facilities,  as defined  herein,  on the terms and conditions  provided
herein for use by PA for conducting its Medical Practice, and Midwest to operate
the  Lab,   which   Facilities   and   Management   Services  will  be  provided
simultaneously to other entities providing Infertility Services.

         PA desires to utilize  the  services of  Management  Company to perform
management and administrative  functions,  on its behalf, to permit PA to devote
its  efforts  on a  concentrated  and  continuous  basis  to  the  rendering  of
Infertility Services to its patients; and Midwest desires to obtain the services
of Management Company to manage and administer the Lab.

         NOW THEREFORE, in consideration of the above recitals which the parties
incorporate  into this  Agreement,  the mutual  covenants and agreements  herein
contained and other good and valuable  consideration , Management Company agrees
to  provide  the  Management  Services  and  the  Facilities  on the  terms  and
conditions provided herein.



                                   ARTICLE 1

                                   DEFINITIONS

1.1 DEFINITIONS.  For the purposes of this Agreement,  the following definitions
shall apply:

                  1.1.1   "Assets"  shall  mean  those  fixed  assets  owned  by
         Management Company and utilized in connection with the operation of the
         Medical  Practice  and the Lab,  including,  but not limited to,  fixed
         assets and leasehold improvements.

                  1.1.2   "Adjustments"  shall  mean  adjustments  for  refunds,
         discounts,  contractual adjustments,  professional courtesies and other
         activities  that  do not  generate  a  collectible  fee  as  reasonably
         determined by Management Company and Providers.

                  1.1.3 "Facilities" shall mean the medical offices and clinical
         spaces  of  Providers,   including  any  satellite  locations,  related
         businesses and all medical group  business  operations of PA, which are
         provided by Management Company and utilized by Providers.

                  1.1.4 "Fiscal Year" shall mean the 12-month  period  beginning
         January 1 and ending December 31 of each year.

                  1.1.5   "Infertility   Services"   shall  mean   gynecological
         services,  treatment of human infertility encompassing the provision of
         in  vitro  fertilization,  and  other  assisted  reproductive  services
         provided by PA, Midwest or any Physician  Employee,  Other Professional
         Employee, or Technical Employee.

                  1.1.6 "Lab  Revenue"  shall mean all fees earned and  actually
         recorded each month (net of Adjustments) based on the accrual method of
         accounting  pursuant  to  generally  accepted   accounting   principles
         ("GAAP") by or on behalf of Midwest as a result of laboratory  services
         furnished by Lab.

                  1.1.7 "Other Professional Employee" shall mean a non-physician
         individual  who  provides   services  to  Providers,   including  nurse
         anesthetists, physician assistants, nurse practitioners, psychologists,
         and  other  such  professional   employees  who  generate  professional
         charges, but shall not include Technical Employees.

                  1.1.8  "RMC  Receivables"  shall  mean,  and  include,   those
         receivables  for  services  rendered  by PA to  RMC  patients  as  more
         particularly  defined in Section 4.3 of that  certain  agreement  among
         Management  Company,  PA and Research Medical Center ("RMC") dated July
         15,  1998  ("RMC  Agreement").  RMC  Receivables  shall not  mean,  and
         excludes,  those  receivables  under  the RMC  Agreement  for  services
         rendered by Management Company to RMC under the RMC Agreement.

                  1.1.9 "PDE" shall mean an amount equal to a) Revenue,  less b)
         the amount  calculated  under Section 7.1.1 plus the amount  calculated
         under Section 7.1.2.

                  1.1.10  "Physician-Employee"  shall mean an individual, who is
         an employee of PA or is  otherwise  under  contract  with PA to provide
         professional  services  to  PA  patients  and  is  duly  licensed  as a
         physician in the state of Missouri.

                  1.1.11 "Physician and Other  Professional  Revenue" shall mean
         all fees earned,  and actually recorded each month (net of Adjustments)
         in  accordance  with  GAAP,  by or on  behalf  of  PA  as a  result  of
         professional medical services personally furnished to patients of PA by
         Physician-Employees or Other Professional Employees,  and other fees or
         income earned in their capacity as  professionals,  whether rendered in
         an  inpatient  or  outpatient  setting,  including  but not limited to,
         medical  director  fees  or  technical  fees  from  medical   ancillary
         services,  consulting fees and ultrasound fees from businesses owned or
         operated by  Physician-Stockholders.  In addition,  Physician and Other
         Professional  Revenue  shall  include  all fees  earned,  and  actually
         recorded each month (net of  Adjustments) in accordance with GAAP, as a
         result of professional  medical services performed by PA for RMC at the
         Facilities   pursuant  to  the  RMC  Agreement.   Physician  and  Other
         Professional  Revenues shall not include (i) board  attendance fees and
         other  compensation  in connection with board  memberships,  (ii) other
         services  where a  Physician-Employee  does  not  provide  professional
         medical    services   such   as   testimony   and    consultation   for
         litigation-related   proceedings,    lectures,   passive   investments,
         fundraising,  or writing ("Permitted Services"),  the compensation from
         which  Permitted  Services such  Physician-Employee  may retain without
         limit,  and (iii)  compensation  resulting from a  Physician-Employee's
         affiliation  with an academic  institution in a teaching  capacity.  PA
         agrees  that  not  less  than 14  days  prior  to a  Physician-Employee
         engaging in an affiliation  with an academic  institution in a teaching
         capacity,  PA  and  the   Physician-Employee   will  obtain  Management
         Company's consent,  which shall not be unreasonably  withheld,  to such
         activities.


                  1.1.12  "Providers'  Receivables"  shall mean and  include all
         rights to  payment  for  services  rendered  or goods  sold,  accounts,
         receivables, contract rights, chattel paper, documents, instruments and
         other evidence of patient  indebtedness to PA or Midwest,  policies and
         certificates of insurance relating to any of the foregoing,  all rights
         to payment,  reimbursement  or settlement or insurance or other medical
         benefit  payments  assigned to PA or Midwest by patients or pursuant to
         any Preferred  Provider,  HMO, capitated payment  agreements,  or other
         agreements between PA and/or a payer, and all of PA's rights to payment
         for  services  rendered  by PA for RMC  patients at the  Facilities  in
         accordance  with  the  RMC  Agreement,  recorded  each  month  (net  of
         Adjustments) in accordance with GAAP. Providers'  Receivables shall not
         include any Medicare or Medicaid receivables.

                  1.1.13   "Receivables"   shall  mean  the  sum  of  Providers'
         Receivables and RMC Receivables.

                  1.1.14  "Revenue"  shall mean the sum of  Physician  and Other
         Professional Revenue, and Lab Revenue.

                  1.1.15  "Technical  Employees"  shall mean technicians such as
         embryologists  and other laboratory  personnel,  ultrasonographers  and
         phlebotomists who provide services to Providers.


                                   ARTICLE 2

                                COST OF SERVICES

2.1 "Cost of  Services"  shall  mean all  ordinary  and  necessary  expenses  of
Providers and all direct ordinary and necessary operating expenses of Management
Company  incurred  in  connection  with the  management  of  Providers,  and the
provision of Facilities,  unless expressly provided otherwise herein,  including
but not limited to:

                  2.1.1 Salaries,  benefits, payroll taxes and other direct cost
         of all Management Company employees working at the Facilities;

                  2.1.2  Expenses  incurred  in the  recruitment  of  additional
         physicians  for PA,  including,  but not limited to  employment  agency
         fees, relocation and interviewing expenses and any actual out-of-pocket
         expenses,  provided  such  out-of-pocket  expenses  are agreed  upon by
         Management  Company  and PA  prior  to being  incurred,  of  Management
         Company  personnel or any  Physician-Employee  in connection  with such
         recruitment effort;

                  2.1.3 Direct marketing expenses of PA, such as direct costs of
         printing marketing materials prepared by Management Company;

                  2.1.4 Any sales and use taxes  assessed  against PA related to
         the operation of PA's medical practice;


                  2.1.5  Lease  payments,   depreciation   expense   (determined
         according  to  GAAP),  taxes  and  interest  directly  relating  to the
         Facilities  and  equipment,   and  other  expenses  of  the  Facilities
         described in Section 3.2 below;

                  2.1.6 Legal fees paid by  Management  Company or PA to outside
         counsel in connection with matters specific to the operation of PA such
         as regulatory  approvals  required as a result of the parties  entering
         into this  Agreement;  provided,  however,  legal fees  incurred by the
         parties  relative to completion  of this  Agreement or as a result of a
         dispute   between  the  parties  under  this  Agreement  shall  not  be
         considered a Cost of Services;

                  2.1.7 All  insurance  necessary to operate PA including  fire,
         theft,    general    liability    and    malpractice    insurance   for
         Physician-Employees of the PA;

                  2.1.8 Professional licensure fees and board certification fees
         of  Physician-Employees,  and Other  Professional  Employees  rendering
         Infertility Services on behalf of PA;

                  2.1.9  Membership in professional  associations and continuing
         professional education for  Physician-Employees  and Other Professional
         Employees;

                  2.1.10 Quality  Improvement  Program  described in Section 3.8
         herein;

                  2.1.11 Cost of filing fictitious name permits pursuant to this
         Agreement;

                  2.1.12 Cost of supplies,  medical and administrative,  and all
         direct general and administrative expenses of PA;

                  2.1.13    $10,000   in   the    aggregate,    annually,    per
         Physician-Employee   for  travel  and   entertainment   expenses,   car
         allowances  (including car leases),  dues and  subscriptions,  cellular
         telephone and other business related expenses relative to PA;

                  2.1.14    $9,000    in   the    aggregate,    annually,    per
         Physician-Employee for health, life and long-term disability insurance;
         and

                  2.1.15  Such other  costs and  expenses  directly  incurred by
         Management Company necessary for the management or operation of PA.

2.2      Management   Company  covenants  and  represents  that  any  management
         agreement  consummated  between  Management  Company and a  Co-Occupant
         shall include a definition  of cost of services  that is  substantially
         the same as the  definition  of Cost of  Services in Section 2.1 of the
         Agreement.

2.3      "Facilities  Cost of  Services"  shall  mean the costs  incurred  under
         Section  2.1 of this  Agreement  plus  the  costs  incurred  under  the
         definition of cost of services  contained in each management  agreement
         consummated between Management Company and a Co-Occupant.

2.4      The amount paid to Management Company monthly by PA pursuant to Section
         7.1.1  hereof  shall cover the Cost of Services  identified  in Section
         2.1.  To the extent that PA requires  services  or  equipment  over and
         above those provided for in, and covered by, Section 2.1, PA shall bear
         the cost of such  services  or  additional  expenses,  which  costs and
         additional  expenses  shall be excluded from  determination  of the PDE
         calculation defined in Section 1.1.9.  Management Company shall have no
         obligation to make any payments for such costs and additional expenses,
         and PA agrees not to incur any such costs or additional expenses in the
         name of Management Company.





                                   ARTICLE 3

                DUTIES AND RESPONSIBILITIES OF MANAGEMENT COMPANY

3.1      MANAGEMENT SERVICES AND ADMINISTRATION.

                  3.1.1  The PA and  Midwest  acknowledge  and  agree  that  the
         Management  Services and Facilities  will be provided to PA and Midwest
         on a  non-exclusive  basis and that such  Management  Services  and the
         Facilities may be shared by other entities and/or medical practices who
         have   signed  a   management   agreement   with   Management   Company
         ("Co-Occupants").  Management  Company will allocate  resources and its
         personnel's time so as to fulfill its obligations under this Agreement.
         Notwithstanding  anything herein to the contrary,  nothing herein shall
         obligate  Management  Company  to devote  all of its  personnel  at the
         Facilities and Management Services to PA, Midwest and Co-Occupants,  to
         the exclusion of anyone of them.

                  3.1.2   Providers   hereby  appoint   Management   Company  as
         Providers' sole and exclusive manager and administrator of all of their
         day-to-day  business  functions  and grant  Management  Company all the
         necessary  authority to carry out, with Providers'  advice and consent,
         its duties and responsibilities pursuant to the terms of this Agreement
         to provide the  Management  Services  on a  non-exclusive  basis.  Only
         Physician-Employees or their designees,  whose credentials are reviewed
         and  approved by  Management  Company  prior to  rendering  any medical
         functions at the Facilities,  will perform the medical functions of the
         Medical Practice.  Management Company will have no authority,  directly
         or indirectly, to perform, and will not perform, any medical function.

                  3.1.3  Management  Company  will, on behalf of PA and Midwest,
         and in  accordance  with  applicable  laws,  bill  patients  and  other
         responsible  persons and  third-party  payors and collect  professional
         fees for  Infertility  Services  rendered by  Providers  to  Providers'
         patients  at  the   Facilities,   outside  the   Facilities   for  PA's
         hospitalized  patients, and for all other Infertility Services rendered
         by any Physician- Employee,  Other Professional  Employee, or Technical
         Employee.  Providers  hereby  appoint  Management  Company for the term
         hereof to be their true and lawful attorney-in-fact,  for the following
         purposes:  (i) to bill patients in Providers' name and on their behalf;
         (ii) to collect  Receivables  resulting from such billing in Providers'
         name and on their  behalf;  (iii) to receive  payments  from  insurance
         companies,  prepayments  received from health care plans, and all other
         third-party  payors; (iv) to take possession of and endorse in the name
         of  Providers  (and/or in the name of any  Physician-Employee  or Other
         Professional Employee rendering Infertility Services to patients of PA)
         any notes,  checks,  money orders,  and other  instruments  received in
         payment of  Receivables;  and (v) to initiate the  institution of legal
         proceedings  in the  name of  Providers,  with  Providers'  advice  and
         consent,  to collect  any  accounts  and monies owed to  Providers,  to
         enforce the rights of either Provider as creditor under any contract or
         in  connection  with  the  rendering  of any  service,  and to  contest
         adjustments  and  denials  by  governmental  agencies  (or  its  fiscal
         intermediaries) as third-party payors.

                  3.1.3.1  Prior to  referring  any  Receivable  to a collection
         agency,  or sending any  letter,  other than a standard  billing  cycle
         statement,  or commencing litigation,  Management Company shall provide
         Providers  with thirty (30) days' written  notice of its intent to take
         such action. If within said period, Providers advise Management Company
         that  Providers  do not want (i) a  particular  Receivable  or any part
         thereof referred to a collection  agency, or (ii) any letter other than
         a standard billing cycle statement sent or (iii) litigation  commenced,
         then Providers will repurchase the Receivable  from Management  Company
         within  thirty  (30) days of such notice from  Management  Company.  If
         Providers  fail to  repurchase  the  Receivable  within the thirty (30)
         days,  Management Company will proceed with such collection efforts, as
         it deems appropriate.






                  3.1.4  Management  Company  will  provide  the  administrative
         services   function  of  supervising  and  maintaining  (on  behalf  of
         Providers)  all files and  records  relating to the  operations  of the
         Facilities,  including  but  not  limited  to  accounting  and  billing
         records,  including for billing purposes,  patient medical records, and
         collection  records.  Patient medical records shall at all times be and
         remain the  property of PA and, if  applicable,  Midwest,  and shall be
         located at the Facilities  and be readily  accessible for patient care.
         Management  Company's  management of all files and records shall comply
         with all applicable state and federal laws and  regulations,  including
         without  limitation,  those  pertaining to  confidentiality  of patient
         records.  The medical records of each patient shall be expressly deemed
         confidential  and shall not be made available to any third party except
         in  compliance  with  all  applicable   laws,  rules  and  regulations.
         Management  Company  shall  have  access  to such  records  in order to
         provide  the  Management   Services   hereunder,   to  perform  billing
         functions, and to prepare for the defense of any lawsuit in which those
         records may be relevant. The obligation to maintain the confidentiality
         of such records shall survive termination of this Agreement.  Providers
         shall have  access,  on  reasonable  notice,  to all of their  records,
         including but not limited to  documentation  of any expense incurred by
         Management Company as Cost of Services,  whether on behalf of Providers
         or, to the extent  Providers  share  payment of the expense,  Providers
         and/or other Co-Occupants, at all times.

                  3.1.5   Management   Company  will  supply  to  Providers  all
         reasonably  necessary  clerical,  accounting,  bookkeeping and computer
         services,   printing,   postage  and  duplication   services,   medical
         transcribing   services,   and  any  other   necessary  or  appropriate
         administrative   services   reasonably   necessary  for  the  efficient
         operation of Providers' businesses at the Facilities.

                  3.1.6   Management   Company,   subject  to  Providers'  prior
         approval,  shall design and assist Providers with the implementation of
         an appropriate marketing and public relations program, with appropriate
         emphasis  on  public  awareness  of  the  availability  of  Infertility
         Services  from PA and the services of Midwest.  The Parties  agree that
         the public  relations  program  shall be conducted in  compliance  with
         applicable  laws and regulations  governing  advertising by the medical
         profession.  Recognizing that Providers'  participation in carrying any
         marketing and public  relations  program is essential,  Providers shall
         participate in developing  advertising  and marketing  strategies,  and
         approve  collateral  materials,  relative to any  marketing  and public
         relations program.

                  3.1.7 Management  Company,  upon request of PA, will assist PA
         in recruiting  additional  physicians,  including  such  administrative
         functions as  advertising  for and  identifying  potential  candidates,
         checking credentials,  and arranging interviews;  provided, however, PA
         shall interview and make the ultimate decision as to the suitability of
         any physician to become associated with PA. All physicians recruited by
         Management  Company  and  accepted  by  PA  shall  be  employees  of or
         independent contractors to PA.

                  3.1.8 Management  Company will assist Providers in negotiating
         any managed care, PPO, HMO and other provider contracts to which either
         Provider   desires  to  become  a  party.   Decisions   regarding   the
         establishment,   maintenance  or  termination  of  relationships   with
         institutional   health  providers  shall  be  made  by  Providers,   in
         consultation with Management  Company.  Management Company will provide
         administrative  assistance to Providers in fulfilling  their respective
         obligations  under any such  contract.  In  connection  with  assisting
         Providers in negotiating  any managed care, PPO, HMO and other provider
         contracts,  Management  Company  will use its best efforts to safeguard
         the confidentiality of Providers' Confidential  Information,  as herein
         defined, as well as to avoid use of Providers' Confidential Information
         for anti-competitive purposes.

                  3.1.9  Management  Company will arrange for legal  services as
         may  be  reasonably  required  in the  ordinary  course  of  Providers'
         operations,  including  the cost of enforcing  any  physician  contract
         containing  restrictive   covenants,   but  excluding  personal  legal,
         accounting and tax services to any Physician-Employee.

                  3.1.10  Management   Company  will  negotiate  for  and  cause
         premiums  to be paid with  respect  to the  insurance  provided  for in
         Article 11.

                  3.1.11  Management  Company  will take such  other  reasonable
         actions to collect fees and pay expenses of the  Facilities in a timely
         manner as are deemed reasonably  necessary to facilitate the operations
         of Providers at the Facilities.






3.2      FACILITIES.  Management Company will provide the Facilities  identified
         in Exhibit 3.2 hereto,  on a  non-exclusive  basis,  necessary  for the
         operation  of the  Medical  Practice  and the  Lab,  including  but not
         limited to, the use of the  Facilities,  all  furniture,  equipment and
         furnishings  necessary  for the proper and  efficient  operation of the
         Facilities, all repairs,  maintenance and improvements thereto, utility
         (telephone,   electric,  gas,  water)  services,  customary  janitorial
         services,  refuse disposal and all other services reasonably  necessary
         in conducting the Facilities' physical  operations.  Management Company
         will  provide  for  the  cleanliness  of  the  Facilities,  and  timely
         maintenance and cleanliness of the equipment, furniture and furnishings
         located therein.

3.3      EXECUTIVE DIRECTOR AND OTHER PERSONNEL.

                  3.3.1  EXECUTIVE  DIRECTOR.  Management  Company will hire and
         appoint a  manager,  subject  to the  approval  of the Joint  Practices
         Management  Board,  to  manage  and  administer  all of the  day-to-day
         business  functions of the Facilities  ("Executive  Director/Manager").
         Management  Company shall determine  salary and fringe benefits paid to
         the  Executive  Director/Manager.  At the  direction,  supervision  and
         control of Management Company, the Executive Director/Manager,  subject
         to the terms of this Agreement, will implement the policies agreed upon
         by the Joint Practices  Management Board and will generally perform the
         administrative  duties  assigned to the Executive  Director/Manager  by
         Management Company.

                  3.3.2  PERSONNEL.  Management  Company will employ and provide
         Other  Professional   Employees,   Technical  Employees,   support  and
         administrative  personnel,  clerical,   secretarial,   bookkeeping  and
         collection  personnel  reasonably necessary for the efficient operation
         of the Providers at the Facilities.  Management Company shall determine
         and cause to be paid the salaries  and  benefits of all such  personnel
         who will be under the direction,  supervision and control of Management
         Company,  with  Technical  Employees and Other  Professional  Employees
         subject  to the  professional  supervision  of PA.  Management  Company
         agrees that Other Professional  Employees and Technical  Employees will
         comply  with  the  reasonable   instructions   of   Physician-Employees
         supervising  such  personnel.  If Providers are  dissatisfied  with the
         services of any person  employed by  Management  Company and working at
         the  Facilities,   Providers  will  consult  with  Management  Company.
         Management Company shall in good faith determine whether the employment
         of that employee  warrants  termination.  The overriding  principle and
         goal of facilitating  the Providers'  provision of high quality medical
         care  and  laboratory   services  will  govern   Management   Company's
         obligations to personnel described herein.  Personnel assignments shall
         be made to ensure consistent and continued rendering of quality support
         services  in the  Facilities  and to  ensure  prompt  availability  and
         accessibility    of    individual     medical    support    staff    to
         Physician-Employees in order to develop constant, familiar, and routine
         working  relationships  between  individual   Physician-Employees   and
         individual  members of the support staff. If Providers disagree with an
         assignment  Providers  may appeal  such  assignment  to the  Management
         Company.  Management  Company shall make every effort  consistent  with
         sound  business  practices to honor the specific  requests of Providers
         with regard to the  assignment of Management  Company's  employees.  In
         addition,  Management  Company,  upon PA's request for nursing or other
         personnel  in excess of such  covered by PA's share of Cost of Services
         as  provided  for in  Section  7.1.1,  shall  assist  PA in  recruiting
         additional  nursing and/or other  personnel  specific or unique to PA's
         Medical Practice.  All recruiting costs, salaries and benefits for such
         personnel shall be borne by PA from PA's share of PDE.






                  3.3.1 OTHER  PROFESSIONAL  EMPLOYEES AND TECHNICAL  EMPLOYEES.
         Management  Company will ensure that each Other  Professional  Employee
         and Technical Employee:

                  3.3.3.1 Maintains a current,  valid,  unrestricted  license or
         other applicable authorization to practice his or her profession in the
         State of Missouri,  and  maintains  good  standing  with the  authority
         responsible for such licensure or authorization;

                  3.3.3.2  Performs  professional  services at the Facilities in
         accordance   with   applicable  laws  and  regulations  and  prevailing
         standards of care in the medical  community and in accordance  with the
         reasonable direction and/or instructions of a Physician-Employee.

                  3.3.3.3  Maintains  his or  her  professional  skills  through
         continuing education and training; and

                  3.3.3.4   Maintains   eligibility   for  insurance  under  the
         professional   liability  policy  or  policies  carried  by  Management
         Company.

3.4  FINANCIAL  PLANNING AND GOALS.  Management  Company will  prepare,  for the
approval of Providers,  an annual  capital and operating  budget (the  "Budget")
reflecting  the  anticipated  Revenue and Cost of Services,  sources and uses of
capital  for  growth  of PA's  practice  and for the  provision  of  Infertility
Services  at the  Facilities.  Management  Company  will  present  the Budget to
Providers for approval at least sixty (60) days prior to the commencement of the
Fiscal Year.  Management  Company will  indicate the targeted  profit margin for
Providers which will be reflected in the Budget. If the parties can not agree on
the Budget for PA for any Fiscal  Year  during the term of this  Agreement,  the
Budget for the preceding Fiscal Year will serve as the Budget until such time as
the dispute can be resolved.

3.5  FINANCIAL  STATEMENTS.  Management  Company will prepare and deliver to the
representative  of each  Provider  provided  for in the  notice  section of this
Agreement an annual management report within sixty (60) days of the close of the
Fiscal Year ("Annual  Management  Report").  Management Company will prepare and
deliver  to the  representative  of each  Provider  provided  for in the  notice
section of this Agreement a monthly management report within twenty (20) days of
the close of each month ("Monthly  Management  Report").  Each Annual or Monthly
Management Report will contain a balance sheet,  statement of operations showing
Revenue and Costs of Services,  and Receivables aging schedule.  The Receivables
aging  schedule  will  indicate  Receivables  aging  for 30,  90 and  120  days.
Providers  have the right to request  from  Management  Company  and inspect all
billing  statements,  original  receipts,  and other  documents  relating to the
management of Providers under this Agreement.

3.6 TAX PLANNING AND TAX RETURNS. Management Company will not be responsible for
any tax  planning or tax return  preparation  for  Providers,  but will  provide
support  documentation  in connection with the same. Such support  documentation
will not be destroyed without Providers consent.




3.7  INVENTORY  AND  SUPPLIES.  Management  Company  shall  order  and  purchase
inventory and supplies, and such other materials that are requested by Providers
to enable PA Midwest to deliver  Infertility  Services in a cost-effective  high
quality manner.

3.8 QUALITY  IMPROVEMENT.  Management  Company shall assist PA in fulfilling its
obligations to maintain a Quality  Improvement  Program and in meeting the goals
and standards of such program.  Management  Company will also establish policies
and  procedures  for  assisting  Providers in offering  Infertility  Services to
patients  under  financial  arrangements  arranged  through third  parties,  and
assisting patients in determining  eligibility for Infertility Services coverage
through patients' medical carriers.

3.9 RISK MANAGEMENT.  Management Company shall assist PA in the development of a
Risk Management Program and in meeting the standards of such Program.

3.10  PERSONNEL  POLICIES  AND  PROCEDURES.  Management  Company  shall  develop
personnel  policies,  procedures  and  guidelines,  to govern  office  behavior,
protocol and procedures, designed to insure that the Facilities observe all laws
and guidelines related to employment and human resources management.

3.11 LICENSES AND PERMITS.  Management  Company  shall,  on behalf of Providers,
coordinate and assist Providers in its application for and efforts to obtain and
maintain all federal,  state and local licenses,  certifications  and regulatory
permits required for or in connection with the operations of PA and Midwest, and
equipment located at the Facilities, including those relating to the practice of
medicine or the administration of drugs by Physician-Employees.

3.12  PRODUCTION  REPORTS.  Within  thirty  (30) days of the  execution  of this
Agreement, Management Company and Providers will mutually agree upon appropriate
periodic  production  reports  that will provide  Providers  with the number and
types of procedures performed by  Physician-Employees,  and the charges for each
such  procedures,  and the  number of  patients  who have  received  Infertility
Services at the Facilities over the applicable  period and the aggregate charges
for all such services. Such production reports shall be produced on no less than
a monthly basis.

                                   ARTICLE 4

                  DUTIES AND RESPONSIBILITIES OF PA AND MIDWEST

4.1 PROFESSIONAL  SERVICES.  PA shall cause its  Physician-Employees  to provide
Infertility  Services to PA's  patients in  compliance at all times with ethical
standards,  laws and  regulations  applying  to the  practice of medicine in the
applicable  jurisdiction  which  such  Physician-Employee  provides  Infertility
Services on behalf of PA. Such  obligation  of PA shall  include  ensuring  that
adequate  patient  coverage is provided at all times for its patients.  PA shall
ensure that each Physician-Employee, any Other Professional Employee employed by
PA, and any other professional  provider  associated with PA is duly licensed to
provide  the  Infertility  Services  being  rendered  within  the  scope of such
provider's practice.  In addition,  PA shall require each  Physician-Employee to
maintain a DEA number and appropriate  medical staff privileges as determined by
PA during the term of this Agreement. In the event that any disciplinary actions
or medical malpractice actions are initiated against any  Physician-Employee  or
other   professional   provider,   PA  shall   promptly   inform  the  Executive
Director/Manager  and provide the  underlying  facts and  circumstances  of such
action,  and the  proposed  course of action to  resolve  the  matter.  Periodic
updates, but not less than monthly, shall be provided to Management Company.

4.2 MEDICAL PRACTICE. PA shall use and occupy the Facilities exclusively for the
purpose of providing  gynecologic services,  Infertility  Services,  and related
services  and shall  comply with all  applicable  laws and  regulations  and all
applicable  standards  of medical  care,  including,  but not limited to,  those
established  by the  American  Society of  Reproductive  Medicine.  The  Medical
Practice  conducted  at the  Facilities  by PA  shall  be  conducted  solely  by
Physician-Employees, and Other Professional Employees employed by PA, Midwest or
Management  Company, as applicable.  No other physician or medical  practitioner
shall be permitted  to use or occupy the  Facilities  without the prior  written
consent of Management  Company,  except in the case of a medical  emergency,  in
which event,  notification shall be provided to Management Company as soon after
such use or occupancy as possible.



4.3 EMPLOYMENT OF PHYSICIAN-EMPLOYEES  AND OTHER PROFESSIONAL  EMPLOYEES. In the
event PA shall  determine that  additional  physicians  are necessary,  PA shall
undertake and use its best efforts to locate  physicians  who, in PA's judgment,
possess  the  credentials  and  expertise  necessary  to enable  such  physician
candidates to become affiliated with PA for the purpose of providing Infertility
Services.  PA shall cause each  Physician-Employee  to enter into an  employment
agreement in a form that is mutually  acceptable  to PA and  Management  Company
("Physician-Employment  Agreement"),  which acceptance shall not be unreasonably
withheld by either party. As long as Elwyn M. Grimes, MD ("Dr. Grimes"), remains
the sole shareholder and  Physician-Employee of PA, Management Company shall not
withhold acceptance of Dr. Grimes'  Physician-Employment  Agreement on the basis
that it lacks a non-compete provision.  Except as otherwise provided in Sections
4.6.4  and  5.2.8 of this  Agreement,  PA shall  have  complete  control  of and
responsibility  for  the  hiring,  compensation,  supervision,  evaluation,  and
termination  of  its  Physician-Employees,   although  at  the  request  of  PA,
Management Company shall consult with PA respecting such matters.

4.4 CONTINUING MEDICAL EDUCATION.  PA shall require its  Physician-Employees  to
participate in such  continuing  medical  education as PA deems to be reasonably
necessary for such  physicians to remain current in the provision of Infertility
Services.

4.5 PROFESSIONAL  INSURANCE  ELIGIBILITY.PA shall cooperate in the obtaining and
retaining   of   professional   liability   insurance   by  assuring   that  its
Physician-Employees  and  Other  Professional  Employees,  if  applicable,   are
insurable  and  participating  in an on-going  Risk  Management  Program,  under
Management Company's directions.

4.6 DIRECTION OF PRACTICE. PA, as a continuing condition of Management Company's
obligations  under  this  Agreement,  shall at all time  during  the Term be and
remain  legally  organized  and  operated to provide  Infertility  Services in a
manner consistent with state and federal laws. In furtherance of which:

                  4.6.1 PA shall  operate and maintain at the  Facilities,  on a
         non-exclusive  basis, a full-time practice of medicine  specializing in
         the provision of  Infertility  Services and shall  maintain and enforce
         the  Physician-Employment  Agreements.  PA covenants  that it shall not
         employ any physician,  or have any physician as a  shareholder,  unless
         said physician  shall sign a Physician  Employment  Agreement  prior to
         assuming the status as employee and/or shareholder of PA.

                  4.6.2  PA  shall   not,   except   in   accordance   with  the
         Physician-Employment Agreement or as otherwise stated herein, terminate
         any    Physician-Employment    Agreement,    amend   or   modify    any
         Physician-Employment  Agreement  in  any  material  manner,  waive  any
         material rights of the PA thereunder without the prior written approval
         of  Management  Company,   which  approval  will  not  be  unreasonably
         withheld.  PA may amend or modify the  Physician-Employment  Agreements
         without Management Company's consent in order to comply with applicable
         law.  In  addition,  in  the  exercise  of  Management  Company's  sole
         discretion, if PA fails to pursue the enforcement of its rights against
         a Physician-Employee,  Management Company shall have the right, but not
         the obligation,  to direct,  initiate,  or join in a lawsuit to enforce
         the  provisions  of any  Physician  Employment  Agreement  and PA shall
         assign its rights and remedies against such Physician-Employee upon the
         request of Management Company.

                  4.6.3  Recognizing  that  Management  Company  would  not have
         entered into this  Agreement  but for the PA's covenant to maintain and
         enforce the Physician-Employment Agreements, subject to the limitations
         stated in Section  4.6.2,  and in reliance upon a  Physician-Employee's
         observance and performance of all of the obligations  under a Physician
         Employment Agreement,  any damages,  liquidated damages,  compensation,
         payment,  or  settlement  received  by the PA  from a  physician  whose
         employment  is  terminated,  shall  be paid to  Management  Company  in
         proportion to Management Company's loss or damages.

                  4.6.4 PA shall  retain that number of  Physician-Employees  as
         are  reasonably   necessary  and   appropriate  for  the  provision  of
         Infertility  Services.  However,  PA agrees  that it will not hire more
         physicians  than consented to by the Joint Practice  Management  Board,
         which  shall  not  be   unreasonable   in  giving  its  consent.   Each
         Physician-Employee  shall hold and  maintain  a valid and  unrestricted
         license to practice medicine in the applicable  jurisdiction where such
         Physician-Employee  provides  Infertility Services on behalf of PA, and
         shall be board eligible in the practice of gynecology, with training in
         the subspecialty of infertility and assisted reproductive  medicine. PA
         shall be  responsible  for paying the  compensation  and  benefits,  as
         applicable,  for  all  Physician-Employees,  and  for  withholding,  as
         required  by law,  any sums for  income  tax,  unemployment  insurance,
         social security,  or any other withholding  required by applicable law.
         Management  Company  may,  on  behalf of the PA,  and at PA's  request,
         administer the compensation with respect to such Physician-Employees in
         accordance  with  the  written   agreement  between  the  PA  and  each
         Physician-Employee. Management Company shall neither control nor direct
         any Physician in the performance of Infertility  Services for patients,
         and  Management  Company  will  not  unreasonably  interfere  with  the
         employer-employee relationship between PA and its Physician-Employees.



                  4.6.5 PA shall insure that Physician-Employees provide patient
         care and clinical backup as required to insure the proper  provision of
         Infertility  Services to patients of the PA at the Facilities set forth
         in Exhibit 3.2,  and/or such other location as shall be mutually agreed
         to  by  PA  and   Management   Company.   PA  shall   insure  that  its
         Physician-Employees  devote  substantially  all of  their  professional
         time,  effort and ability to PA's practice,  including the provision of
         Infertility  Services and the  development of such  practice.  PA shall
         insure that  Physician-Employees  timely  (within 24 hours of rendering
         services) note in all patient charts, any and all procedures  performed
         and  services   rendered  so  that  proper   billing  of  patients  and
         third-party payors can be performed by Management Company.

                  4.6.6 PA  covenants to obtain  necessary  licenses and operate
         clinical  laboratory  and tissue bank services in  accordance  with all
         applicable laws and regulations. PA agrees that any Medical Director(s)
         or  Tissue  Bank  Director(s)  shall  be  Physician-Employees  or Other
         Professional  Employees,  if  applicable,   of  the  PA  who  meet  the
         qualifications required by applicable State law or regulation, and that
         should there be a vacancy in any such  position,  PA will cause another
         Physician-Employee or Other Professional  Employee,  if applicable,  to
         fill such vacancy in accordance with applicable State law.

                  4.6.7 PA acknowledges that it bears all medical obligations to
         patients  treated at the  Facilities  and PA and Midwest  covenant that
         they are responsible for all tissue,  specimens,  embryos or biological
         material  ("Biological  Materials") kept at the Facilities on behalf of
         the patients (or former  patients) of PA or Midwest.  In the event of a
         termination or dissolution of PA or Midwest, or the termination of this
         Agreement  for any reason,  PA and Midwest will have the  obligation to
         account to its  patients  and to arrange for the storage or disposal of
         such  Biological  Materials in accordance  with patient consent and the
         ethical  guidelines of the American  Society of  Reproductive  Medicine
         ("Relocation Program"). Management Company, in such event, will, at the
         request  of the PA,  assist  in the  administrative  details  of such a
         Relocation Program.  These obligations shall survive the termination of
         this Agreement.

                  4.6.8  Except for  circumstances  outside the control of PA or
         Shareholders  of PA, PA  covenants  not to  terminate  or dissolve as a
         professional  services  corporation  except on six months prior written
         notice to Management  Company.  In the event that such  termination  or
         dissolution  occurs, for a reason other than the death or disability of
         all of the shareholders,  or any successor entity fails to continue the
         medical practice of PA  substantially in the form  contemplated by this
         Agreement,  PA  and  its  individual   shareholders,   shall  indemnify
         Management  Company  for:  (a) the  actual  costs  of  maintaining  the
         Facilities and any reasonably  necessary Other  Professional  Employees
         during a  Relocation  Program  (Section  4.6.7);  and (b) any  damages,
         costs,  liabilities,  including reasonable attorneys fees, arising from
         claims, suits, causes of action or proceedings, brought by a patient of
         the PA having  an  interest  in any  Biological  Materials  kept at the
         Facilities.  These  obligations  shall survive the  termination of this
         Agreement.



4.7      PHYSICIAN-EMPLOYEES,  SUPERVISION OF OTHER  PROFESSIONAL  AND TECHNICAL
         EMPLOYEES. PA will ensure that each Physician-Employee:

                  4.7.1  Maintains  a current,  valid,  unrestricted  license or
         other applicable authorization to practice his or her profession in the
         State of Missouri,  and maintains good and  unrestricted  standing with
         the authority responsible for such licensure or authorization;

                  4.7.2  Performs  professional  services at the  Facilities  in
         accordance   with   applicable  laws  and  regulations  and  prevailing
         standards of care in the community;

                  4.7.3  Maintains  his  or  her  professional   skills  through
         continuing education and training;

                  4.7.4 Maintains eligibility for insurance; and

                  4.7.5 Does not ask or direct any Management  Company  employee
         to engage in any conduct that violates any federal,  local or state law
         or  regulation,  or ask or direct any  Management  Company  employee to
         engage in conduct for which said employee is not licensed to perform or
         engage.

4.8 PRACTICE DEVELOPMENT,  COLLECTION EFFORTS AND NETWORK INVOLVEMENT. PA agrees
that during the term of this Agreement, PA covenants for itself and will use its
best efforts to cause its Physician-Employees to:

                  4.8.1 Execute such  documents  and take such steps  reasonably
         necessary  to  assist  billing  and  collecting  for  patient  services
         rendered by PA, Midwest and Physician-Employees;

                  4.8.2 Promote PA's medical practice and Midwest's  Infertility
         Services and participate in marketing  efforts  developed by Management
         Company, and approved by PA and the Joint Practices Management Board.

                  4.8.3 Participate in Management Company  Reproductive  Science
         Center  Network  activities  and  programs  such as the  Physician  and
         Scientist Council.

4.9   PERSONNEL   POLICIES.   PA  covenants   for  itself  and  will  cause  its
Physician-Employees  and any other employees to comply with reasonable personnel
policies and guidelines  developed for the PA and Midwest by Management  Company
and/or the Joint Practice  Management Board, which shall include  administrative
protocols and policies  designed to insure that the  Facilities  comply with all
applicable laws and regulations, federal, state and local.

4.10 MIDWEST.  Midwest shall provide clinical laboratory services to patients in
compliance  at all  times  with  all  applicable  ethical  standards,  laws  and
regulations.




                                   ARTICLE 5

                        JOINT DUTIES AND RESPONSIBILITIES

5.1 FORMATION  AND OPERATION OF JOINT  PRACTICES  MANAGEMENT  BOARD.  Management
Company,  PA and Co-Occupants will establish a joint practices  management board
("Joint  Practices  Management  Board") which will be responsible for developing
management  and  administrative  policies  for  the  overall  operation  of  the
Facilities.  The Joint  Practices  Management  Board will consist of  designated
management  representatives from Management Company, one representative from PA,
one from each Co-Occupant, and the Executive Director/ Manager. It is the intent
and  objective  of  Management  Company  and PA that they  agree on the  overall
operations of the Facilities. In the case of any matter requiring a formal vote,
PA shall  have one (1) vote,  each  Co-Occupant  shall  have one (1)  vote,  and
Management  Company  shall  have one (1) vote.  The  desire  is that  Management
Company,  PA and  Co-Occupants  agree on matters of operations and that, if they
disagree, they will have to work cooperatively to resolve any disagreement.

5.2 DUTIES AND  RESPONSIBILITIES  OF THE JOINT PRACTICES  MANAGEMENT  BOARD. The
Joint Practices  Management Board shall have, among others, the following duties
and responsibilities:

                  5.2.1 ANNUAL BUDGETS AND PROFITABILITY. All annual capital and
         operation  budgets  prepared by Management  Company for the  Facilities
         shall be subject to the review, amendment, approval, and disapproval of
         the Joint Practices  Management Board.  Providers covenant and agree to
         use their best efforts to agree upon the budgets, in place from time to
         time. Providers and Management Company agree that,  recognizing changes
         in circumstances,  annual budgets and forecast are subject to revisions
         and, accordingly,  they will cause the Joint Practices Management Board
         to modify the annual budgets, as needed,  including without limitation,
         staff  reductions,  to ensure that  Providers  operate in a  profitable
         mode, subject to Management Company's duties and responsibilities under
         this Agreement.

                  5.2.2 CAPITAL IMPROVEMENTS AND EXPANSION.  Except as otherwise
         provided  herein,  any  renovation  and  expansion  plans,  and capital
         equipment expenditures with respect to the Facilities shall be reviewed
         and approved by the Joint Practices Management Board and shall be based
         upon the best interests of all  occupants,  and shall take into account
         capital   priorities,   economic   feasibility,    physician   support,
         productivity and then current market and regulatory conditions.

                  5.2.3  ADVERTISING  BUDGET.  All annual  advertising and other
         marketing  budgets for the  Facilities  prepared by Management  Company
         shall be subject to the review, amendment,  approval and disapproval of
         the Joint Practices Management Board.

                  5.2.4 PATIENT FEES. Providers, in their sole discretion, shall
         determine an  appropriate  fee schedule for all physician and ancillary
         services rendered by Providers at the Facilities.

                  5.2.5 ANCILLARY SERVICES. The Joint Practices Management Board
         shall approve ancillary services rendered at the Facilities.

                  5.2.6 STRATEGIC PLANNING. The Joint Practices Management Board
         shall,  to the extent  permitted by applicable law,  develop  long-term
         strategic plans, from time to time.

                  5.2.7 PHYSICIAN HIRING.  The Joint Practices  Management Board
         shall, in conjunction  with PA and  Co-Occupants,  determine the number
         and type of  physicians  required  for the  efficient  operation of the
         Facilities.



                  5.2.8 EXECUTIVE DIRECTOR AND KEY PERSONNEL.

                  (a)   The   selection   and   retention   of   the   Executive
         Director/Manager  pursuant to Section 3.3.1 by Management Company shall
         be  subject to the  recommendation  of the Joint  Practices  Management
         Board.  If PA  is  dissatisfied  with  the  services  provided  by  the
         Executive  Director/Manager,  PA shall consult with Management  Company
         who shall,  in good faith,  determine  whether the  performance  of the
         Executive  Director/Manager  could  be  brought  to  acceptable  levels
         through   counsel   and   assistance,    or   whether   the   Executive
         Director/Manager should be terminated.

                  (b) Management Company shall follow the recommendations of the
         Joint   Practices   Management   Board  with  respect  to  the  hiring,
         terminating, or relocating of key personnel at the Facilities, provided
         such  recommendations  do not cause  Management  Company to violate any
         federal, state or local laws or regulations.

5.3 FEE  SCHEDULES.  PA  understands  and agrees  that each  Co-Occupant  of the
Facilities may establish and publish its own separate and distinct fee schedule,
and  nothing  herein  shall  obligate  PA to  share  its  fee  schedule  with  a
Co-Occupant or utilize the schedule of a Co-Occupant.  Upon request of patients,
third parties,  or governmental  agencies,  Management Company personnel will be
permitted to disclose PA's fee schedule.

                                   ARTICLE 6

                       LICENSE OF MANAGEMENT COMPANY NAME

6.1 GRANT OF LICENSE. Management Company hereby grants to Providers a revocable,
non-exclusive and  non-assignable  license for the term of this Agreement to use
the name  REPRODUCTIVE  SCIENCE  ASSOCIATES and a revocable,  non-exclusive  and
non-assignable  license with respect to any other service names, trademark names
and logos of  Management  Company (the "Trade  Names") in  conjunction  with the
provision of Infertility Services at the Facilities.

6.2 FICTITIOUS NAME PERMIT. If necessary,  PA and Midwest shall file or cause to
be filed  an  original,  amended  or  renewal  application  with an  appropriate
regulatory agency to obtain a fictitious name permit which allows PA and Midwest
to  practice  at the  Facilities  under the Trade Names and shall take any other
actions  reasonably  necessary to procure  protection  of or protect  Management
Company's  rights to the Trade Names.  Management  Company  shall  cooperate and
assist PA and  Midwest  in  obtaining  any such  original,  amended  or  renewal
fictitious name permit.

6.3  RIGHTS  OF  MANAGEMENT  COMPANY.  PA  and  Midwest  acknowledge  Management
Company's  exclusive  right,  ownership,  title and interest in and to the Trade
Names  and  will  not at any  time  do or  cause  to be done  any  act or  thing
contesting  or in any way impairing or tending to impair any part of such right,
title  and  interest.  In  connection  with the use of the Trade  Names,  PA and
Midwest shall not in any manner represent that it has any ownership  interest in
the  Trade  Names,  and PA's and  Midwest's  use  shall  not  create in PA's and
Midwest's  favor any right,  title,  or  interest in or to the Trade Names other
than the right of use granted  hereunder,  and all such uses by PA Midwest shall
inure  to the  benefit  of  Management  Company.  PA and  Midwest  shall  notify
Management  Company  immediately upon becoming aware of any claim, suit or other
action brought against it for use of the Trade Names or the  unauthorized use of
the Trade Names by a third party. PA and Midwest shall not take any other action
to protect  the Trade  Names  without the prior  written  consent of  Management
Company.  Management  Company,  if it so desires,  may commence or prosecute any
claim  or suit in its own name or in the  name of PA or  Midwest  or join PA and
Midwest as a party  thereto.  PA and Midwest  shall not have any rights  against
Management Company for damages or other remedy by reason of any determination of
Management Company not to act or by reason of any settlement to which Management
Company may agree with  respect to any  alleged  infringements,  imitations,  or
unauthorized use by others of the Trade Names, nor shall any such  determination
of  Management  Company or such  settlement  by  Management  Company  affect the
validity or enforceability of this Agreement.



6.4      RIGHTS UPON TERMINATION.

                  6.4.1  Upon  termination  of this  Agreement,  PA and  Midwest
         shall:  (i) within 30 days of the  termination,  cease  using the Trade
         Names in all  respects  and refrain  from making any  reference  on its
         letterhead or other  publicly-disseminated  information  or material to
         its former relationship with Management Company;  and (ii) take any and
         all actions  required to make the Trade Names  available for use by any
         other person or entity designated by Management Company.

                  6.4.2 PA's or Midwest's failure (except as otherwise  provided
         herein) to cease using the Trade Names at the termination or expiration
         of this  Agreement will result in immediate and  irreparable  damage to
         Management  Company  and to the rights of any  licensee  of  Management
         Company.  There is no adequate  remedy at law for such failure.  In the
         event  of  such  failure,  Management  Company  shall  be  entitled  to
         equitable  relief by way of injunctive  relief and such other relief as
         any court with  jurisdiction  may deem just and  proper.  Additionally,
         pending  such a hearing and the  decision on the  application  for such
         permanent  injunction,  Management  Company  shall  be  entitled  to  a
         temporary  restraining  order,  without  prejudice  to any other remedy
         available to Management  Company.  All such remedies hereunder shall be
         at the expense of PA and Midwest and shall not be a Cost of Services.





                                   ARTICLE 7

                             FINANCIAL ARRANGEMENTS

7.1 COMPENSATION.  The compensation set forth in this Article 7 is being paid to
Management  Company in  consideration  of the  substantial  commitment  made and
services  to be  rendered  by  Management  Company  hereunder  and is  fair  and
reasonable. Management Company shall be paid the following amounts (collectively
"Compensation"):

                  7.1.1 Based on Providers' current staffing and operations, for
         the first 12  months of this  Agreement,  $75,000  per month  ("Initial
         Monthly  Cost of  Services")  for all Cost of Services  provided for in
         Section 2.1  (whether  incurred  by  Management  Company or  Providers)
         accrued by Management  Company pursuant to the terms of this Agreement.
         Beginning  with the 13th  month of this  Agreement  and on a  quarterly
         basis thereafter, the Initial Monthly Cost of Services will be adjusted
         and,  as  adjusted,  will  equal the  product  of (i)  Revenue  for the
         previous 3 months  divided by total  revenue for all  medical  services
         provided at the  Facilities  for the previous 3 months,  multiplied  by
         (ii) Facilities  Cost of Services for the previous 3 months  ("Adjusted
         Monthly  Cost of  Services").  Notwithstanding  the above,  neither the
         Initial  Monthly  Cost of Services  nor the  Adjusted  Monthly  Cost of
         Services for the 36-month period beginning May 1, 1999 and ending April
         30, 2002, shall exceed $75,000 per month.

                  7.1.1.1  Notwithstanding  the provisions of Section 7.1.1,  in
         the event that  Co-Occupants  begin utilizing the Facilities during the
         first 12 months of this Agreement,  cost of services paid to Management
         Company by all occupants,  including Providers, for the first 12 months
         of this Agreement, in excess of the Facilities Cost of Services for the
         first 12 months of this Agreement shall be remitted to Providers within
         60 days after the first 12 months of this Agreement.

                  7.1.1.2 PA and Management  Company recognize and agree that it
         is in their mutual best interests to cooperate in bringing Co-Occupants
         into the  Facility.  Accordingly,  Providers  agree to use  their  best
         efforts  to  assist  Management  Company  in  consummating   management
         agreements with other  Co-Occupants  as soon as possible.  In the event
         Management Company successfully consummates a management agreement with
         a Co-Occupant  on or before October 31, 1999,  Management  Company will
         pay  $7,500.00  to PA. In the  event  Management  Company  successfully
         consummates  a management  agreement  with a second  Co-Occupant  on or
         before October 31, 1999,  Management  Company will pay PA an additional
         $15,000.00.  All  payments  under  this  Section  will be paid to PA as
         follows:  one-third of the total on the effective  date of the relevant
         management agreement between Management Company and a Co-Occupant,  and
         the remaining  two-thirds in two equal monthly  payments 30 days and 60
         days after the  effective  date of the relevant  management  agreement.
         This offer  expires at  midnight,  October  31,  1999,  except that any
         payments due  thereafter  based on  management  agreements  consummated
         prior  to  that  date  will be paid in  accordance  with  the  schedule
         provided for in this Section 7.1.1.2.

                  7.1.2 During each year of this  Agreement,  a Base  Management
         Fee, paid monthly but reconciled to annual Revenues, of an amount equal
         to six percent (6%) of Revenues;

                  7.1.3  During  each  year of  this  Agreement,  an  Additional
         Management Fee, paid monthly but reconciled to annual operating results
         of PA, equal to 20% of PDE; provided,  however,  the first $8,333.33 of
         monthly PDE and the first $100,000 of annual PDE shall inure to PA;

                  7.1.4 In the event that Section 7.1.2 and/or  Section 7.1.3 of
         this  Agreement is found to be illegal,  unenforceable,  against public
         policy,  or forbidden by law, by any local,  state or federal agency or
         department, or any court of competent jurisdiction  ("Findings"),  then
         Section 7.1.2 and/or 7.1.3 and the Base  Management  Fee and Additional
         Management Fee shall be replaced, effective immediately and retroactive
         tot he date of  this  Agreement,  by a  fixed  annual  Management  Fee,
         payable in equal monthly installments  ("Alternate  Management Fee") on
         or  before  the  15th  business  day  of  each  month.  Said  Alternate
         Management Fee shall be an amount mutually  agreed upon,  within thirty
         (30) day's  time from the  Findings,  between  Management  Company  and
         Providers;  however,  pending such agreement,  the Alternate Management
         Fee shall be $96,700 per annum.  In the event of a Finding which causes
         the Alternate  Management Fee to become  operative,  the parties shall,
         within  sixty (60) days of the Finding,  account for all payments  made
         prior to the date of the Finding, and recalculate such amounts pursuant
         to the  formula  provided  for in the  Alternate  Management  Fee.  Any
         overpayment to Management  Company resulting from the prior application
         of Sections 7.1.2 and/or 7.1.3 shall be applied so as to satisfy 50% of
         each future  monthly  Alternate  Management  Fee until the aggregate of
         such overpayment is fully paid by Management Company.  Any underpayment
         to Management  Company resulting from the prior application of Sections
         7.1.2 and/or 7.1.3 shall be paid to  Management  Company  commencing on
         the first day of the next full month following the date of the Finding,
         in eighteen (18) equally monthly installments.



                  7.1.5 The right of  termination  provided for in Section 9.1.3
         of this Agreement,  if based on the fact that Section 7.1.2 and Section
         7.1.3 of this Agreement  have been found to be illegal,  unenforceable,
         void,  against  public  policy  or  forbidden  by  law,  shall  only be
         exercisable  in the event  that both (i)  Sections  7.1.2 and 7.1.3 and
         (ii) the Alternate  Management Fee have been so found by a local, state
         or federal agency or department, or a court of competent jurisdiction.

7.2      MONTHLY NET INCOME.

                  7.2.1  On or  before  the  15th  business  day of each  month,
         Management  Company shall calculate the Receivables  arising during the
         previous  calendar  month.  Subject to the terms and conditions of this
         Agreement,  PA and Midwest hereby sell and assign to Management Company
         as absolute  owner,  and  Management  Company hereby agrees to purchase
         from PA and Midwest all such Receivables following their calculation by
         Management  Company  as  above.  All  Receivables  are  sold  on a full
         recourse basis. PA and Midwest shall cooperate with Management  Company
         and execute all necessary documents in connection with the purchase and
         assignment of such  Receivables to Management  Company or at Management
         Company's  option,  to its lenders.  All collections in respect of such
         Receivables  shall be deposited in a bank account at a bank  designated
         by  Management  Company.  To  the  extent  PA  or  Midwest  comes  into
         possession  of any  payments  in  respect of such  Receivables,  PA and
         Midwest shall direct such payments to Management Company for deposit in
         bank accounts designated by Management Company.

                  7.2.2  Each  month  during  the  term  of  the  Agreement,  in
         consideration for Providers' transfer and sale of the previous calendar
         month's  Receivables to Management  Company in accordance  with Section
         7.2.1,  Management  Company shall pay to PA the sum of the  Receivables
         for the previous  calendar  month,  less  Compensation  due  Management
         Company for the previous  calendar month  calculated in accordance with
         Section 7.1  ("Monthly  Net  Income") on the first and third  Friday of
         each  calendar  month,  with the first  payment  of each month to equal
         $7,500 and the second payment of each month to equal Monthly Net Income
         for the previous calendar month less $7,500.  For the month of May 1999
         only, both payments shall equal $7,500.





7.3 PRIOR DEBT AND COVENANT BY PHYSICIAN.  PA and Management Company acknowledge
and agree that effective as the date hereof PA is indebted to Management Company
in the amount set forth on Exhibit  7.3(A) ("PA Debt") as a result of the Former
Agreements.  Management Company  acknowledges that it has no right to payment of
PA Debt from Midwest. PA hereby covenants and represents that the obligation for
payment of the PA Debt is PA's. PA and Management Company agree that the PA Debt
will be evidenced by a note (the "Note") in the form attached  hereto as Exhibit
7.3(B).

                  7.3.1 On the  anniversary  date of this  Agreement  during the
         term of the Agreement,  Management Company will deduct $166,953.60 from
         the PA Debt.  This  provision  shall  survive the  termination  of this
         Agreement if Dr. Grimes  continues to provide  Infertility  Services at
         the Facilities.

                  7.3.2 In the event this  Agreement  terminates  for any reason
         prior to the satisfaction of the Note and Dr. Grimes no longer provides
         Infertility  Services  at the  Facilities,  PA agrees to pay the unpaid
         balance of the Note within 90 days of the termination.


                                  ARTICLE 8

                       EXCLUSIVE MANAGEMENT RIGHT AND TERM

8.1 In consideration of the considerable  investment of time and resources in PA
and Midwest expected by Management  Company,  PA and Midwest grant to Management
Company the  exclusive  right to manage PA and  Midwest  during the term of this
Agreement (the "Exclusive Management Right").

8.2 The term of this Agreement  shall begin May 1, 1999 (the  "Effective  Date")
and shall expire May 1, 2004 (the "Term") unless earlier terminated  pursuant to
Article 9, below.  This Agreement may be renewed by either party,  if within the
period of 180 days prior to the  expiration  date one party gives  notice to the
other of its  intention  to  continue  this  Agreement  under the same terms and
conditions as set forth herein or under such  different  terms and conditions as
particularly  set forth in the  written  notice and further  providing  that the
other party has 30 days from the date of notice to accept,  reject or modify the
offer.  If within 30 days, the other party does not respond or by written notice
accepts,  this  Agreement  shall  continue for an  additional 10 years under the
terms and conditions as provided in the notice.

8.3 PA and  Midwest  acknowledge  and  agree  that they  have  been  advised  by
Management Company,  that Management Company is currently negotiating with other
parties, the names of which have been disclosed to them, that may result in such
other parties utilizing and having access to the Facilities. Although Management
Company has not finalized such negotiations,  PA and Midwest understand that the
results of such  negotiations  may impact  this  Agreement.  Management  Company
intends to  continue  with such  negotiations  and will use its best  efforts to
preserve the economic benefits anticipated by PA and Midwest hereunder.



                                   ARTICLE 9

                          TERMINATION OF THE AGREEMENT

9.1      TERMINATION

         Either  party  in  the  event  of  the  following  may  terminate  this
Agreement:

                  9.1.1 Insolvency. If a receiver,  liquidator or trustee of any
         party shall be appointed by court  order,  or a petition to  reorganize
         shall be filed against any party under any bankruptcy,  reorganization,
         or  insolvency  law, and shall not be dismissed  within 90 days, or any
         party shall file a voluntary  petition in bankruptcy or make assignment
         for the  benefit  of  creditors,  then  either  Management  Company  or
         Providers  may  terminate  this  Agreement  upon 10 days prior  written
         notice to the other parties.

                  9.1.2 MATERIAL BREACH. If either party shall materially breach
         its  obligations  hereunder,  then the other party may  terminate  this
         Agreement by providing 30 days prior  written  notice to the  breaching
         party  detailing  the nature of the breach and  providing the breaching
         party with the  opportunity  to cure the  breach.  If the breach is not
         cured  within such  30-day  period,  this  Agreement  shall  terminate,
         provided  that if the breach is not curable  within such 30-day  period
         and the breaching party is making  diligent  efforts to cure the breach
         during such 30-day period, this Agreement shall not terminate. If after
         the exercise of diligent  efforts,  the breaching party shall be unable
         to cure the breach  within 60 days from the  notice of breach  from the
         non-breaching party, the non-breaching party in its sole discretion may
         extend  the  time in  which to cure the  breach,  upon  request  of the
         breaching party. In the event the  non-breaching  party does not extend
         the time in which to cue the breach,  this  Agreement will terminate at
         the  expiration of 60 days from the original  notice of breach from the
         non-breaching party.

                  9.1.3  ILLEGALITY.  Any party  may  terminate  this  Agreement
         immediately  upon  receipt  of  notification  by any local,  state,  or
         federal  agency or court of  competent  jurisdiction  that the  conduct
         contemplated  by this  Agreement is forbidden by law;  except that this
         Agreement  shall not  terminate  during  such  period of time as to any
         party which  contests such  notification  in good faith and the conduct
         contemplated  by this  Agreement  is allowed to  continue  during  such
         contest.  If any governing  regulatory agency asserts that the services
         provided by  Management  Company  under this  Agreement are unlawful or
         that the practice of medicine by PA as  contemplated  by this Agreement
         requires a certificate of need, and any such assertion is not contested
         (or if  contested,  the agency's  assertion is found to be correct by a
         court of  competent  jurisdiction  and no appeal  is  taken,  or if any
         appeals are taken and the same are unsuccessful),  this Agreement shall
         thereupon terminate with the same force as if such termination date was
         the date  originally  specified in this  Agreement as the date of final
         expiration of the terms of this Agreement.

9.2  TERMINATION  BY  MANAGEMENT  COMPANY This  Agreement  may be  terminated by
Management Company for the following reasons:

                  9.2.1  FOR  PROFESSIONAL  DISCIPLINARY  ACTIONS.  PA  shall be
         obligated  to suspend a  Physician-Employee  whose  license to practice
         medicine in Missouri is suspended,  revoked, or not renewed. Management
         Company may terminate  this Agreement upon 10 days prior written notice
         to  PA  if a  Physician-Employee's  license  to  practice  medicine  is
         suspended,  revoked,  or not renewed and PA has failed to suspend  such
         Physician-Employee;  provided,  however,  such  action may not be taken
         until  PA  has  been  given  30  days  to  resolve   such   physician's
         authorization  to  practice  medicine  in  Missouri.  PA  shall  notify
         Management   Company   within   five  (5)  days  of  a  notice  that  a
         Physician-Employee's  license  to  practice  medicine  in  Missouri  is
         suspended,  revoked,  or not renewed or that formal disciplinary action
         has been taken  against a physician  which could  reasonably  lead to a
         suspension, revocation, or non-renewal of a physician's license.

9.3 TERMINATION BY PA OR MIDWEST.  PA or Midwest may terminate this Agreement in
the event that a Physician-Employee who is also a shareholder in PA and Midwest,
and is the only Physician-Employee, dies or becomes disabled.

9.4 TERMINATION WITHOUT CAUSE. Either party may terminate this Agreement without
cause by notifying the other party in writing 90 days before the effective  date
of the termination.






                                   ARTICLE 10

                  PURCHASE OF ASSETS - OBLIGATIONS AND OPTIONS

10.1 TERMINATION BY MANAGEMENT  COMPANY.  If Management  Company terminates this
Agreement due to the insolvency of PA or Midwest (Section 9.1.1), for a material
breach  by  PA  or  Midwest   (Section   9.1.2),   or  PA  fails  to  suspend  a
Physician-Employee  whose license is suspended,  revoked or not renewed (Section
9.2.1),  PA and/or Midwest  agree,  within 90 days of the date of termination of
this  Agreement,  at Management  Company's  option,  to purchase from Management
Company the Assets as more fully set forth in Sections  10.1.1 and 10.1.3  below
if there is no Co-Occupant.

                  10.1.1 The  purchase  price of the Assets will be the net book
         value determined in accordance with GAAP,  consistently  applied, as at
         the date of the termination.

                  10.1.2 In addition to purchasing the Assets,  PA shall satisfy
         any remaining obligations under the Note.

                  10.1.3 If a purchase is completed under Section 10.1, PA shall
         assume all leases for  offices  and  equipment  used  directly  for the
         management  and  operation of Providers'  businesses  and may hire such
         employees from Management Company as Providers chose. In such event, PA
         shall be  obligated  to  indemnify  Management  Company for any and all
         severance or termination  obligations to Management  Company  employees
         utilized  directly  in  providing  Management  Services  whom  are  not
         subsequently hired by PA or Midwest.

10.2 TERMINATION BY PA. In the event PA terminates this Agreement as a result of
the insolvency of Management  Company  (9.1.1) or material  breach by Management
Company (9.1.2),  PA's obligations under the Note shall continue to be satisfied
in accordance with the Note.




                                   ARTICLE 11

                                    INSURANCE

11.1  Management  Company  shall use its best  efforts to cause PA to be made an
additional insured under Management Company's  professional  liability coverage;
provided,  however, conditions for being made an additional insured shall be (i)
PA utilizing  patient  informed  consent forms  supplied by Management  Company,
provided such forms are  consistent  with law and any  guidelines  issued by the
American   Society  of   Reproductive   Medicine  and  (ii)  PA  complying  with
requirements of Management Company's insurance company. Management Company shall
also carry a policy of public  liability  and  property  damage  insurance  with
respect to the Facilities under which the insurer agrees to indemnify Management
Company  and PA against all cost,  expense  and/or  liability  arising out of or
based upon any and all  claims,  accidents,  injuries  and  damages  customarily
included  within the  coverage  of such  policies  of  insurance  available  for
Management  Company.  The minimum limits of liability of such insurance shall be
$1 million  combined  single limit covering  bodily injury and property  damage.
Certificates of Insurance evidencing such policies and additional insured status
shall be  presented  to PA  within  thirty  (30) days  after  such  coverage  is
effected.

11.2 In the  event  Management  Company  is  unable  to  cause  PA to be made an
additional insured under Management Company's  professional  liability coverage,
PA  shall  procure  and  maintain   throughout  the  Term  of  this   Agreement,
professional  liability  insurance  covering itself and its employees  providing
Infertility  Services  pursuant to this  Agreement  in the minimum  amount of $1
million per incident,  $3 million in the aggregate.  If possible under the terms
of such coverage,  PA shall use its best efforts to cause Management  Company to
be named an additional insured.  Evidence of such coverage shall be presented to
Management Company within 30 days of the execution of this Agreement.

11.3 PA and  Management  Company  shall provide  written  notice to the other at
least  thirty  (30) days in  advance  of the  effective  date of any  reduction,
cancellation  or  termination  of the  insurance  required to be carried by each
hereunder.




                                   ARTICLE 12

                                  MISCELLANEOUS

12.1 INDEPENDENT CONTRACTOR.  Management Company, PA and Midwest are independent
contracting parties. In this regard, the parties agree that:

                  12.1.1 The relationship between Management Company, and PA and
         Midwest is that of an independent  supplier of non-medical services and
         a medical practice and provider of laboratory  services,  respectively,
         and, unless otherwise provided herein,  nothing in this Agreement shall
         be  construed  to  create  a  principal-agent,   employer-employee,  or
         master-servant  relationship  between  Management  Company  and  PA and
         Midwest;

                  12.1.2  Notwithstanding  the  authority  granted to Management
         Company  herein,  Management  Company and PA agree that PA shall retain
         the full  authority  to direct all of the  medical,  professional,  and
         ethical aspects of its medical practices;

                  12.1.3  Any powers of  Providers  not  specifically  vested in
         Management  Company by the terms of this  Agreement  shall  remain with
         Providers;

                  12.1.4   PA   shall,   at   all   times,    employ   the   (i)
         Physician-Employees,  and (ii) Other Professional Employees required by
         law to be employees of PA. The parties shall be solely  responsible for
         the payment of all applicable  federal,  state, or local withholding or
         similar taxes and  provision of workers'  compensation  and  disability
         insurance for their respective employees;

                  12.1.5 No party  shall  have the right to  participate  in any
         benefits,  employment programs or plans sponsored by the other party on
         behalf of the other party's employees,  including,  but not limited to,
         workers' compensation,  unemployment insurance, tax withholding, health
         insurance,  life  insurance,  pension  plans,  or  any  profit  sharing
         arrangement;

                  12.1.6 In no event  shall any party be liable for the debts or
         obligations  of  any  other  party  except  as  otherwise  specifically
         provided in this Agreement; and

                  12.1.7 Matters involving the internal  agreements and finances
         of  Providers,  including  but  not  limited  to  the  distribution  of
         professional fee income among  Physician-Employees  and, if applicable,
         Other Professional Employees who are providing professional services to
         patients of Providers, and other employees of Providers, disposition of
         Providers  property  and  stock,  accounting,   tax  preparation,   tax
         planning,  and pension and investment  planning (and expenses  relating
         solely  to these  internal  business  matters),  hiring  and  firing of
         Physician-Employees,  decisions  and contents of reports to  regulatory
         authorities  governing  Providers and licensing,  shall remain the sole
         responsibility of Providers and the individual  Physician-Employees who
         are  Shareholders  of  Providers,  except with respect to the number of
         Physician-Employees  the  Providers  hire  which  will  be  based  upon
         recommendations of the Joint Practices Management Board.

12.2 FORCE MAJEURE. No party shall be liable to the other parties for failure to
perform any of the  services  required  under this  Agreement  in the event of a
strike,  lockout,  calamity,  act of God,  unavailability of supplies,  or other
event over which such party has no control,  for so long as such event continues
and for a reasonable period of time thereafter, and in no event shall such party
be  liable  for  consequential,  indirect,  incidental  or like  damages  caused
thereby.



12.3 EQUITABLE RELIEF.  Without limiting other possible remedies  available to a
non-breaching party for the breach of the covenants contained herein,  including
the right of Management Company to cause PA to enforce any and all provisions of
the Physician Employment Agreements described in Section 4.3 hereof,  injunctive
or other equitable  relief shall be available to enforce those  covenants,  such
relief to be without the  necessity of posting bond,  cash or otherwise.  If any
restriction contained in said covenants is held by any court to be unenforceable
or  unreasonable,  a lesser  restriction  shall be  enforced  in its  place  and
remaining restrictions therein shall be enforced independently of each other.

12.4  PRIOR  AGREEMENTS;   AMENDMENTS.   This  Agreement  supersedes  all  prior
agreements  and  understandings,  including the Former  Agreements,  between the
parties as to the subject matter covered  hereunder,  and this Agreement may not
be amended,  altered,  changed or terminated  orally. No amendment,  alteration,
change or  attempted  waiver of any of the  provisions  hereof  shall be binding
without the written  consent of all  parties,  and such  amendment,  alteration,
change,  termination  or  waiver  shall in no way  affect  the  other  terms and
conditions of this  Agreement,  which in all other respects shall remain in full
force.

12.5 ASSIGNMENT;  BINDING EFFECT.  This Agreement and the rights and obligations
hereunder may not be assigned  without the prior  written  consent of all of the
parties,  and any attempted assignment without such consent shall be void and of
no force and effect, except that Management Company may assign this Agreement to
any affiliate, which for purposes of this Agreement, shall include any parent or
subsidiary of Management  Company,  without the consent of PA. The provisions of
this  Agreement  shall be  binding  upon and shall  inure to the  benefit of the
parties'  respective  heirs,  legal  representatives,  successors  and permitted
assigns.

12.6 WAIVER OF BREACH.  The failure to insist upon strict compliance with any of
the terms,  covenants or conditions  herein shall not be deemed a waiver of such
terms,  covenants or conditions,  nor shall any waiver or  relinquishment of any
right at any one or more  times be  deemed a waiver  or  relinquishment  of such
right at any other time or times.

12.7  GOVERNING  LAW.  This  Agreement  shall be  governed by and  construed  in
accordance with the laws of the State of Missouri, irrespective of the principal
place of business  of the  parties  hereto.  Any and all  claims,  disputes,  or
controversies arising under, out of, or in connection with this Agreement or any
breach  thereof,  except for equitable  relief sought pursuant to Section 6.4 or
Section 12.3 hereof,  shall be determined by binding arbitration in the State of
Missouri,  City of Kansas City  (hereinafter  "Arbitration").  The party seeking
determination shall subject any such dispute, claim or controversy to either (i)
JAMS/Endispute or (ii) the American  Arbitration  Association,  and the rules of
commercial  arbitration  of the selected  entity shall govern.  The  Arbitration
shall be  conducted  and  decided by three (3)  arbitrators,  unless the parties
mutually agree, in writing at the time of the Arbitration, to fewer arbitrators.
In reaching a decision,  the  arbitrators  shall have no  authority to change or
modify  any  provision  of this  Agreement,  including  any  liquidated  damages
provision.  Each party shall bear its own expenses and one-half the expenses and
costs of the  arbitrators.  Any  application to compel  Arbitration,  confirm or
vacate an arbitral award or otherwise enforce this Paragraph shall be brought in
the Courts of the State of Missouri or the United States  District Court for the
District of Missouri,  to whose jurisdiction for such purposes PA and Management
Company hereby irrevocably consent and submit.

12.8  SEPARABILITY.  If any portion of the provisions hereof shall to any extent
be invalid or unenforceable, the remainder of this Agreement, or the application
of such portion or provisions in  circumstances  other than those in which it is
held invalid or unenforceable,  shall not be affected thereby,  and each portion
or provision of this Agreement shall be valid and enforced to the fullest extent
permitted  by law, but only to the extent the same  continues to reflect  fairly
the intent and understanding of the parties expressed by this Agreement taken as
a whole.

12.9 HEADINGS. Section and paragraph headings are not part of this Agreement and
are included  solely for convenience and are not intended to be full or accurate
descriptions of the contents thereof.

12.10  NOTICES.  Any notice or other  communication  required by or which may be
given  pursuant to this Agreement  shall be in writing and mailed,  certified or
registered  mail,  postage  prepaid,  return  receipt  requested,  or  overnight
delivery  service,  such as FedEx or  Airborne  Express,  prepaid,  and shall be
deemed given when postmarked or when placed with any such delivery service.  Any
such notice or communication shall be sent to the address set forth below:




                  12.10.1 If for Management Company:

                  Gerardo Canet, President
                  IntegraMed America, Inc.
                  One Manhattanville Road
                  Purchase, New York 10577

                  With copies to:

                  Claude E. White, Esq.
                  General Counsel
                  IntegraMed America Inc.
                  One Manhattanville Road
                  Purchase, New York 10577

                12.10.2

                If for PA:

                Elwyn M. Grimes, MD, President
                Reproductive Endocrine & Fertility Consultants, P.A.
                Two Brush Creek
                Suite 500
                Kansas City, Missouri 64112

                With copies to:

                Douglas M. Salaway, Esq.
                Polsinelli, White, Vardeman & Shalton, P.C.
                West 47th Street, Suite 1000
                Kansas City, Missouri 64112

12.10.3         If for Midwest:

                 Elwyn M. Grimes, MD, President
                 Midwest Fertility Foundations & Laboratory, Inc.
                 Two Brush Creek
                 Suite 500
                 Kansas City, Missouri 64112

                 With copies to:

                 Douglas M. Salaway, Esq.
                 Polsinelli, White, Vardeman & Shalton, P.C.
                 West 47th Street, Suite 1000
                 Kansas City, Missouri 64112

         Any party hereto,  by like notice to the other  parties,  may designate
such other address or addresses to which notice must be sent.

12.11 ENTIRE AGREEMENT.  This Agreement and all attachments hereto represent the
entire  understanding  of the parties  hereto with respect to the subject matter
hereof  and  thereof,   and  cancel  and  supersede  all  prior  agreements  and
understandings among the parties hereto,  whether oral or written,  with respect
to such subject matter.

12.12 NO MEDICAL  PRACTICE BY MANAGEMENT  COMPANY.  Management  Company will not
engage in any activity that  constitutes  the practice of medicine,  and nothing
contained  in this  Agreement  is intended to  authorize  Management  Company to
engage in the practice of medicine or any other licensed profession.






12.13    CONFIDENTIAL INFORMATION.

                  12.13.1  During the initial  term and any  renewal  term(s) of
         this  Agreement,  the parties  may have access to or become  acquainted
         with each other's trade secrets and other  confidential  or proprietary
         knowledge  or  information  concerning  the conduct and details of each
         party's business ("Confidential Information").  At all times during and
         after the  termination  of this  Agreement,  no party shall directly or
         indirectly,   communicate,  disclose,  divulge,  publish  or  otherwise
         express to any individual or governmental or non-governmental entity or
         authority  (individually  and collectively  referred to as "Person") or
         use for its own benefit,  except in connection  with the performance or
         enforcement  of  this  Agreement,  or the  benefit  of any  Person  any
         Confidential  Information,  no matter how or when acquired,  of another
         party.  Each party shall cause each of its  employees  to be advised of
         the Confidential  nature of such Confidential  Information and to agree
         to abide by the confidentiality terms of this Agreement. No party shall
         photocopy  or  otherwise  duplicate  any  Confidential  Information  of
         another  party without the prior  express  written  consent of the such
         other  party  except as is  required  to  perform  services  under this
         Agreement. All such Confidential Information shall remain the exclusive
         property of the  proprietor  and shall be  returned  to the  proprietor
         immediately upon any termination of this Agreement.

                  12.13.2 Confidential Information shall not include information
         which (i) is or becomes known through no fault of a party hereto;  (ii)
         is learned by a party from a third-party  legally  entitled to disclose
         such information;  or (iii) was already known to a party at the time of
         disclosure by the disclosing party.

                  12.13.3 In order to minimize  any  misunderstanding  regarding
         what   information  is  considered  to  be  Confidential   Information,
         Management  Company or Providers will designate at each other's request
         the  specific   information  which  Management   Company  or  Providers
         considers to be Confidential Information.






12.14    INDEMNIFICATION.

                  12.14.1  Management  Company  agrees  to  indemnify  and  hold
         harmless PA, its,  shareholders,  directors,  officers,  employees  and
         servants  from any  suits,  claims,  actions,  losses,  liabilities  or
         expenses  (including  reasonable  attorney's fees) arising out of or in
         connection with any act or failure to act by Management Company related
         to the  performance  of its  duties  and  responsibilities  under  this
         Agreement.  The  obligations  contained in this Section  12.14.1  shall
         survive termination of this Agreement.

                  12.14.2 PA agrees to indemnify  and hold  harmless  Management
         Company, its shareholders,  directors, officers, employees and servants
         from any  suits,  claims,  actions,  losses,  liabilities  or  expenses
         (including  reasonable attorney's fees) arising out of or in connection
         with any act or failure to act by PA related to the  performance of its
         duties and  responsibilities  under  this  Agreement.  The  obligations
         contained in this Section  12.14.2  shall survive  termination  of this
         Agreement.






         IN WITNESS  WHEREOF,  this  Agreement  has been executed by the parties
hereto as of the day and year first above written.


INTEGRAMED AMERICA, INC.


By: /s/Donald S. Wood
    ---------------------------------------------
    DONALD S. WOOD, PH.D., SENIOR VICE PRESIDENT
    & CHIEF OPERATING OFFICER

REPRODUCTIVE ENDOCRINE & FERTILITY CONSULTANTS, P.A.


BY: /s/Elwyn M. Grimes
    ---------------------------------------------
    ELWYN M. GRIMES, MD, PRESIDENT

MIDWEST FERTILITY FOUNDATIONS & LABORATORY, INC.


BY:/s/Elwyn M. Grimes
   ----------------------------------------------
   ELWYN M. GRIMES, MD, PRESIDENT





                                   EXHIBIT 3.2

                              OFFICE AND FACILITIES
               TO BE PROVIDED BY MANAGEMENT COMPANY TO PA AND LAB




             Two Brush Creek, Suite 500, Kansas City, Missouri 64112





                                 EXHIBIT 7.4(A)


                        PA DEBT (AS OF DECEMBER 31, 1998)


$   923,101       Advances balance as of December 31, 1998
    175,000       Note Balance at December 31, 1998 ($250,000 Original Amount)
   --------

$ 1,098,101       Balance Due IntegraMed America Inc. as of December 31, 1998

    263,333       Unpaid Right to Manage Fees
  =========
$   834,768       Balance of PA Debt owed to IntegraMed America Inc.

























                                 EXHIBIT 7.4 (B)

                                 PROMISSORY NOTE




                                 [See attached]