Among

                    INTEGRAMED PHARMACEUTICAL SERVICES, INC.,

                         IVP PHARMACEUTICAL CARE, INC.,

                                       And

                            INTEGRAMED AMERICA, INC.

         THIS MANAGEMENT  AGREEMENT  ("Agreement"),  dated effective as of April
21,  1999  (the  "Effective  Date"),  is made  and  entered  into  by and  among
IntegraMed Pharmaceutical Services, Inc., a Texas corporation with its principal
place of business at 2833 Trinity  Square Drive,  Suite 170,  Carrollton,  Texas
75006 ("IPSI"),  IVP  Pharmaceutical  Care,  Inc., a Texas  corporation with its
principal place of business at 2833 Trinity Square Drive, Suite 105, Carrollton,
Texas 75006 ("IVP"),  and IntegraMed America,  Inc., a Delaware corporation with
its principal place of business at One Manhattanville Road,  Purchase,  New York
10577 ("IntegraMed").

                                    RECITALS

         0.1 WHEREAS,  IVP is a licenced  pharmacy  specializing  in  dispensing
ingestable,  injectable,  and  infusion  drugs,  pharmaceuticals,  and  products
related to the treatment of human infertility, pursuant to the prescription of a
duly licensed and authorized physician ("Pharmaceutical  Products"), to end-user
patients ("Customers");

         0.2 WHEREAS,  IntegraMed has developed,  and may develop in the future,
relationships with certain Reproductive Science Centers in the United States and
the infertility medical practices associated therewith,  as set forth on Exhibit
0.2 attached hereto,  as may be amended from time to time (such existing and any
future Reproductive Science Centers and associated infertility medical practices
shall hereinafter be referred to collectively as the "Medical Practices");

         0.3 WHEREAS,  IPSI is a for-profit  corporation formed by IntegraMed to
be engaged in the retail distribution of Pharmaceutical Products to Customers of
the Medical Practices ("Pharmaceutical Services");

         0.4 WHEREAS,  IntegraMed owns all of the  outstanding  capital stock of
IPSI and has agreed to provide advertising,  promotional, and marketing services
to IPSI  under  the terms  and  conditions  set  forth  herein  (the  "Marketing
Services");

         0.6 WHEREAS,  IntegraMed desires to cause IPSI to engage IVP to provide
such  management,  administrative,   business,  and  pharmacy  services  as  are
necessary  and  appropriate  for the conduct and  day-to-day  administration  of
IPSI'S Pharmaceutical Services (the "Management Services"); and

         0.7  WHEREAS,  IVP has agreed to be  retained  by IPSI to  perform  the
Management Services, under the terms and conditions set forth herein;

          0.8 NOW, THEREFORE,  in consideration of the foregoing premises and of
the mutual  covenants and obligations set forth herein,  and for such other good
and  valuable  consideration  the  receipt and  sufficiency  of which are hereby
acknowledged,  the  parties  to this  Agreement  hereby  covenant  and  agree as
follows:


                                    ARTICLE 1

                                   DEFINITIONS

         1.1  DEFINITIONS.  For the purposes of this  Agreement,  the  following
definitions shall apply:

                  1.1.1  "Cost of  Operations"  shall mean a monthly fee paid by
         IPSI to IVP on the first day of each month for the items  described  in
         Section 2.1 below.  Cost of Operations  shall equal that  percentage of
         the Net  Revenues of IPSI  realized or accrued  during the  immediately
         preceding month as set forth on Exhibit 1.1.1 attached  hereto,  as may
         be amended from time to time.

                  1.1.2 "Cost of Pharmaceutical Products" shall mean the cost of
         Pharmaceutical  Products sold on behalf of IPSI to Customers of Medical
         Practices and shall equal IVP's wholesale cost for such  Pharmaceutical
         Products,  as set forth on Exhibit  1.1.2  attached  hereto,  as may be
         amended from time to time.

                  1.1.3  "Collections" shall mean all payments actually received
         by or on  behalf  of  IPSI  from  the  distribution  of  Pharmaceutical
         Products and the provision of Pharmaceutical Services.

                  1.1.4 "Cycle Kit" shall mean the packaging  format and patient
         education  materials that IVP supplies to Customers under the tradename
         "Cycle Kit(TM)."

                  1.1.5  "Dedicated  Assets"  shall  mean  those  fixed  assets,
         including  equipment,  furniture,  and  systems,  purchased by IPSI and
         dedicated exclusively to the provision of Pharmaceutical Services by or
         on behalf of IPSI.

                  1.1.6   "Direct   Costs"   shall  mean  the  cost  of  outside
         accountants and attorneys who provide services directly to IPSI.

                  1.1.7  "Employees"   shall  mean  such  accounting,   nursing,
         pharmacy,  secretarial,   receptionist,  and  billing  and  collections
         personnel necessary for IPSI to provide Pharmaceutical  Services.  Such
         Employees may be employees exclusively of IPSI,  exclusively of IVP, or
         may be independent contractors or leased employees.

                  1.1.8  "Facilities" shall initially mean the office and space,
         including  furniture and fixtures,  situated  initially at 2833 Trinity
         Square Drive,  Suite 170,  Carrollton,  Texas 75006, or such additional
         facilities  determined  by  the  JOB to be  necessary  to  conduct  the
         Pharmaceutical Services.

                  1.1.9 "Fiscal Year" shall mean the 12-month  period  beginning
         January 1 and ending December 31 of each year.

                  1.1.10  "GAAP"  shall  mean  generally   accepted   accounting
         principles applied to public companies in the United States.

                  1.1.11 "JOB" shall mean the Joint Operating Board described in
         Section 5.1 below.

                  1.1.12  "Just-in-time  basis"  shall mean that  Pharmaceutical
         Products shall be delivered to IPSI at a point in time  contemporaneous
         with the time for distribution by IPSI to Customers; provided, however,
         a minimal  inventory,  not to exceed  the  dollar  amount  set forth on
         Exhibit 1.1.12  attached  hereto,  as may be amended from time to time,
         may be  maintained  at the  Facilities  at all times during the Term of
         this Agreement (as defined in Section 8.2 below).

                  1.1.13 "month" shall mean a calendar month.

                  1.1.14  "Net  Revenues"  shall  mean gross  revenues  that are
         earned and  recorded in  accordance  with GAAP less  contractual  sales
         discounts.



                                    ARTICLE 2

                COST OF OPERATIONS AND ADDITIONAL MANAGEMENT FEE

         2.1 OPERATIONS. Operations shall include, and Costs of Operations shall
reimburse,  cover,  and  fully  compensate  IVP for,  the  following  costs  and
expenses, which shall be paid on behalf of IPSI to IVP:

                  2.1.1  Salaries,  fringe  benefits,  payroll taxes,  and other
costs of employing or retaining Employees.

                  2.1.2  Expenses  incurred in the  recruitment of Employees for
         IPSI, including,  but not limited to employment agency fees, relocation
         and interviewing expenses, and any actual out-of-pocket expenses of IVP
         personnel in connection with such recruitment effort;

                  2.1.3 Any sales and use taxes assessed  against IVP related to
         the operation of IPSI'S business;

                  2.1.4 Lease  payments,  depreciation  expense  (determined  in
         accordance with GAAP),  interest,  and property taxes directly relating
         to the  Facilities  and equipment,  utilities,  waste removal,  and all
         other expenses of the Facilities described in Section 3.2 below;

                  2.1.5 Professional and regulatory licensure fees;

                  2.1.6  Insurance  premiums  that are paid with  respect to the
         insurance delineated in Article 11 below.

                  2.1.7 Such other costs and expenses  actually  incurred by IVP
         reasonably necessary for the provision of the Management Services under
         this Agreement.

         2.2 Notwithstanding  anything to the contrary contained herein, Cost of
Operations shall not include the following:

                  2.2.1 Direct Costs;

                  2.2.2 The Additional Management Fee;

                  2.2.3 Any federal or state income or  franchise  taxes of IPSI
         or IVP; or

                  2.2.4 Cost of Pharmaceutical Products.

                                    ARTICLE 3

                       DUTIES AND RESPONSIBILITIES OF IVP

         3.1 MANAGEMENT SERVICES AND  ADMINISTRATION.  IVP agrees to provide the
Management  Services  provided  for in this  Section  3.1, all of which shall be
covered by and included in the Cost of Operations and the Additional  Management
Fee, if any.



                  3.1.1 IPSI hereby  appoints  IVP as IPSI'S sole and  exclusive
         manager  and  administrator  of all of its  day-to-day  operations  and
         business functions and grants IVP all the necessary  authority to carry
         out its  duties  and  responsibilities  pursuant  to the  terms of this
         Agreement.

                  3.1.2 IVP shall,  on behalf of IPSI, bill patients and collect
         fees for  Pharmaceutical  Products supplied to Customers of the Medical
         Practices.  IPSI hereby  appoints IVP during the Term of this Agreement
         to be its true and lawful attorney-in-fact, for the following purposes:
         (a) to bill  patients in IPSI'S name and on its behalf;  (b) to collect
         accounts  receivable  resulting from such billing in IPSI'S name and on
         its  behalf;   (c)  to  receive  payments  from  insurance   companies,
         prepayments  received from health care plans, and all other third-party
         payors;  (d) to open in the name of IPSI such  savings,  checking,  and
         other accounts at such financial institutions as IVP deems appropriate;
         (e) to take  possession  of and  endorse in the name of IPSI any notes,
         checks,  money  orders,  and other  instruments  received in payment of
         accounts  receivable;  and (f) with  the  consent  of  IPSI,  not to be
         unreasonably withheld, to initiate the institution of legal proceedings
         in the name of IPSI,  to collect any  accounts and monies owed to IPSI,
         to enforce  the rights of IPSI as  creditor  under any  contract  or in
         connection   with  the  rendering  of  any  service,   and  to  contest
         adjustments  and  denials  by  governmental  agencies  (or  its  fiscal
         intermediaries) as third-party payors.

                  3.1.3 IVP shall supervise and maintain (on behalf of IPSI) all
         files  and  records  relating  to the  operations  of  the  Facilities,
         including,   but  not  limited  to,  accounting  and  billing  records,
         prescription  records,  and collection  records.  Prescription  records
         shall at all  times be and  remain  the  property  of IVP and  shall be
         located at the  Facilities  and be readily  accessible  to IPSI.  IVP's
         management  of all files and records  shall comply with all  applicable
         state and federal laws and regulations,  including, without limitation,
         those pertaining to  confidentiality  of patient  records.  The records
         relating to patients shall be expressly  deemed  confidential and shall
         not be made available to any third party except in compliance  with all
         applicable laws,  rules, and regulations.  IVP may utilize such records
         in  order  to  provide  the  services  hereunder,  to  perform  billing
         functions, and to prepare for the defense of any lawsuit in which those
         records may be relevant. The obligation to maintain the confidentiality
         of such records shall survive termination of this Agreement. IPSI shall
         have unrestricted access to all of such records at all times.

                  3.1.4  IVP  shall  supply  to IPSI  all  reasonably  necessary
         management,  administrative,  supervisory, nursing, pharmacy, clerical,
         accounting  and  bookkeeping  Employees  necessary to provide,  and IVP
         shall provide,  quality and competent pharmacy services to Customers of
         IPSI. IVP shall provide such computer services,  printing,  postage and
         duplication   services,   and  any  other   necessary  or   appropriate
         administrative  services  reasonably  necessary  for the  operation  of
         IPSI'S Pharmaceutical  Services.  IVP shall have the responsibility for
         hiring,  supervising,   promoting,  reprimanding,   suspending,  and/or
         reinstating  and  terminating  all  Employees   consistent  with  IVP's
         policies and procedures applicable to IVP's own employees.

                  3.1.5 IVP shall arrange for such legal and accounting services
         as may be  reasonably  required  in the  ordinary  course of the IPSI'S
         operation;  provided,  however,  that IVP shall  have no  authority  to
         arrange  for any legal or  accounting  services  to the extent that the
         interests  of IVP and IPSI in the matter in question  shall be adverse.
         IVP will  provide  IPSI  with all  bookkeeping  services  necessary  to
         support IPSI'S Pharmaceutical Services,  including, without limitation,
         maintenance,  custody, and supervision of all business records, papers,
         documents,   ledgers,   journals  and  reports,  and  the  preparation,
         distribution,  and recordation of all bills and statements for services
         rendered by IPSI,  including the billing and  completion of reports and
         forms required by insurance companies,  governmental agencies, or other
         third-party payors.

                  3.1.6 IVP shall open  appropriate bank accounts in the name of
         IPSI and shall deposit the proceeds of all Capitalization Loans and all
         Collections in such bank accounts and pay Costs of Operations, Costs of
         Pharmaceutical  Products,  Direct Costs, the Additional Management Fee,
         if  any,  taxes,  the  repayment  of  Capitalization   Loans,  and  the
         distribution of Net Profits from such bank accounts.

                  3.1.7 In connection with any  Pharmaceutical  Products sold to
         IPSI, IVP shall provide CycleKits and any patient educational materials
         in  the  same  manner  as it  provides  such  to  Customers  purchasing
         Pharmaceutical Products directly from IVP.



         3.2      FACILITIES.

                  3.2.1  IVP  shall  arrange  for  such  Facilities   reasonably
         necessary for the proper operation of IPSI'S  Pharmaceutical  Services.
         IVP shall  arrange for and ensure that all  repairs,  maintenance,  and
         improvements  thereto,   utility  (telephone,   electric,  gas,  water)
         services, customary janitorial services, refuse disposal, and all other
         services  reasonably  necessary in conducting the Facilities'  physical
         operations.  IVP shall ensure the  cleanliness of the  Facilities,  and
         timely  maintenance  and cleanliness of the equipment,  furniture,  and
         furnishings located therein.  IVP shall consult with IPSI regarding the
         condition,  use,  and needs for the  Facilities,  including  equipment,
         services, and improvements thereto. The Facilities may be rented and/or
         purchased  and may be  designated  for IPSI'S  sole and  exclusive  use
         and/or  may be  shared  with  IVP or  with  any  person  or  entity.  A
         description  of the initial  Facilities  are set forth on Exhibit 3.2.1
         attached hereto.

                  3.2.2  In  the  reasonable   judgment  of  the  JOB  based  on
         recommendations  of IVP, IVP and the IPSI may  establish  such other or
         additional Facilities for the operation of the business of IPSI.

                  3.2.3 IVP (a) shall  purchase  for its own  account at its own
         cost,   and   shall   maintain   in  its  own   inventory,   sufficient
         Pharmaceutical  Products  as may be  necessary  from  time  to  time to
         satisfy IPSI'S  Pharmaceutical  Services in a timely fashion; (b) shall
         sell  to  IPSI,  at the  Cost of  Pharmaceutical  Products,  only  such
         Pharmaceutical  Products  as  are  necessary  to  fill  the  orders  of
         Customers of the Medical  Practices on a  just-in-time  basis;  and (c)
         shall  distribute  such  Pharmaceutical  Products to  Customers  of the
         Medical   Practices  in  accordance   with  all  applicable   laws  and
         regulations and as prescribed by physicians associated with the Medical
         Practices. Cost of Pharmaceutical Products shall be paid by IPSI to IVP
         under the following schedule:  Pharmaceutical  Products sold during the
         first  15 days of a month  shall  be paid  for on the  25th day of such
         month; Pharmaceutical Products sold during the 16th day through the end
         of the  month  shall  be  paid  on  the  10th  day  of the  immediately
         succeeding month.

         3.3 FINANCIAL  PLANNING AND GOALS.  IVP shall prepare an annual capital
and operating  budget for IPSI reflecting the anticipated  revenues and expenses
and sources and uses of capital for growth of IPSI'S business at the Facilities.
IVP shall  present the budget to the JOB for its approval at least 30 days prior
to the  commencement of the Fiscal Year. If the JOB does not agree on the budget
or any aspect thereof for any Fiscal Year, the budget,  or portion of the budget
in  disagreement,  for the preceding Fiscal Year shall serve as the budget until
such time as a budget is the subject of agreement.

         3.4      FlNANCIAL STATEMENTS.

                  3.4.1 IVP shall arrange for the  preparation of, and within 30
         days following the end of each Fiscal Year shall present to IPSI, (a) a
         balance sheet, dated as of the last day of such Fiscal Year; (b) a cash
         flow statement  showing the cash flows for the month and for the entire
         Fiscal Year then concluded;  and (c) a statement showing the income and
         expenses  of IPSI for the month  and for the  entire  Fiscal  Year then
         concluded. At the election of IntegraMed expressed in writing to IVP at
         least  90  days  prior  to the  end of a  Fiscal  Year,  the  financial
         statements  referred  to in  this  Section  3.4  shall  be  audited  by
         PriceWaterhouseCoopers  or other  independent  certified public account
         approved  by  the  JOB.  IVP's  failure  to  present  annual  financial
         statements to IPSI in accordance with this Section 3.4.1 within 45 days
         following the end of the Fiscal Year shall be deemed a material  breach
         subject to Section 9.1.2 below.

                  3.4.2 IVP shall prepare, and within six days following the end
         of each month shall present to IPSI,  (a) an unaudited  balance  sheet,
         dated as of the  last  day of such  month;  (b) a cash  flow  statement
         showing  the cash flow for the month and for the  Fiscal  Year to date;
         and (c) a statement  showing  the income and  expenses of IPSI for such
         month and for the Fiscal Year to date.

         3.5 INVENTORY AND SUPPLIES.  IVP shall order and purchase inventory and
supplies,  other than Pharmaceutical  Products governed by Section 3.2.3 of this
Agreement,  and such other  materials that are  reasonably  requested by IPSI to
enable  IPSI'S  Pharmaceutical  Services  to be  conducted  in a  cost-effective
manner.

         3.6 LICENSES AND  PERMITS.  IVP shall,  on behalf of and in the name of
IVP or, at the election of IVP, in the name of IPSI, coordinate and maintain all
pharmacy and other licenses,  permits,  and certificates of authority  necessary
for the conduct of IPSI'S Pharmaceutical Services.



                                    ARTICLE 4

               DUTIES AND RESPONSIBILITIES OF INTEGRAMED AND IPSI

         4.1 USE OF FACILITIES.  IntegraMed  shall take such reasonable steps as
are  necessary  to cause IPSI to use and occupy,  and IPSI shall use and occupy,
the Facilities exclusively for the purpose of providing  Pharmaceutical Services
to Customers of Medical Practices.

         4.2 LICENCES AND PERMITS.  IntegraMed and IPSI covenant to use diligent
efforts to cooperate with IVP in order to obtain  necessary  licenses,  permits,
and  certificates  of  authority  necessary  for IPSI to conduct  Pharmaceutical
Services.

         4.3  PARTICIPATION  IN MANAGEMENT.  IPSI,  while  delegating all of the
day-to-day operations of its business through this Management  Agreement,  shall
nonetheless actively participate in such management through its participation in
the JOB and the presence of its Employees at the Facilities.  IntegraMed, as the
sole shareholder of IPSI,  shall  participate in the supervision of IPSI through
(a)  its  election  of its  representative  to the  JOB;  and  (b)  its  review,
supervision,  and/or  audit  of the  Management  Services  provided  under  this
Agreement. IntegraMed hereby agrees that all compensation,  expenses, and travel
costs for its  officers,  directors,  employees,  and  consultants,  other  than
Employees, shall be paid by IntegraMed.

         4.4  COOPERATION  WITH IVP. IPSI and  IntegraMed  agree that during the
Term of this Agreement, they will use their best efforts to cause their officers
and employees to execute such documents, agreements, notifications, and consents
and take such  steps  reasonably  necessary  to  assist  IVP in  conducting  its
Management  Services  under this  Agreement  and in billing and  collecting  for
Pharmaceutical Products sold.

         4.5 SALES AND MARKETING.  Marketing Services on behalf of IPSI shall be
performed  exclusively  by IntegraMed  at its sole cost and expense.  IntegraMed
shall  prepare  an  annual  sales  and  marketing  plan for IPSI  detailing  its
anticipated activities in such regard.  IntegraMed shall present the plan to the
JOB for its  approval at least 45 days prior to the  commencement  of the Fiscal
Year. If the JOB does not agree on the plan or any aspect thereof for any Fiscal
Year, the plan, or portion of the plan in disagreement, for the preceding Fiscal
Year  shall  serve as the  plan  until  such  time as a plan is the  subject  of
agreement.

         4.6 ADDITIONAL COVENANTS OF IPSI AND INTEGRAMED.  IPSI hereby covenants
that,  during the Term of this  Agreement,  it will not do any of the following:
(a) except  with the consent of the JOB,  enter into any line of business  other
than the sale of Pharmaceutical Products and Pharmaceutical Services pursuant to
this  Agreement;  (b) incur any  indebtedness  except  as  contemplated  in this
Agreement;  or (c) merge,  consolidate,  liquidate, or sell all or substantially
all of its assets.  IntegraMed  hereby  covenants that,  during the Term of this
Agreement,  it will not sell,  assign,  convey,  or transfer  its stock in IPSI.
Either of IPSI'S or  IntegraMed's  breach of this  Section 4.6 shall be deemed a
material breach subject to Section 9.1.2 below.



                                    ARTICLE 5

                        JOINT DUTIES AND RESPONSIBILITIES

         5.1  FORMATION  AND  OPERATION  OF  JOINT  OPERATIONS  BOARD.  IVP  and
IntegraMed  shall  establish a Joint  Operations  Board ("JOB"),  which shall be
responsible  for  developing  management  and  administrative  policies  for the
overall  operation of IPSI.  IntegraMed  and IVP shall each be entitled to elect
two members to the JOB, provided, however, that each party shall be allowed only
one vote on each matter  submitted to the JOB for its vote. The  representatives
of IntegraMed and IVP on the JOB shall be either directors or executive officers
of their respective parties.

         5.2      DUTIES AND RESPONSIBILITIES OF THE JOB. The JOB shall have the
following duties and responsibilities:

                  5.2.1 ANNUAL BUDGETS AND MARKETING  PLANS.  All annual capital
         and  operation  budgets  prepared  by IVP,  and all  sales,  marketing,
         advertising,  and promotions  plans  prepared by  IntegraMed,  shall be
         subject to the review,  amendment,  approval, and/or disapproval of the
         JOB. Approval shall not be unreasonably withheld.

                  5.2.2 CAPITAL IMPROVEMENTS AND EXPANSION.  Except as otherwise
         provided  herein,   any  capital   improvements  with  respect  to  any
         Facilities  and expansion  plans with respect to IPSI shall be reviewed
         and  approved by the JOB and shall be based upon the best  interests of
         IPSI,  and  shall  take  into  account  capital  priorities,   economic
         feasibility,  productivity  and  then  current  market  and  regulatory
         conditions.

                  5.2.3 CAPITALIZATION  LOANS. The JOB shall have the sole power
         to authorize and direct Capitalization Loans.

                  5.2.4  STRATEGIC  PLANNING.  The JOB shall  develop  long-term
         strategic plans, from time to time.

                  5.2.5 RETAIL PRICING POLICIES.  The JOB shall establish retail
         pricing policies.

                  5.2.6  PROVIDER  CONTRACT.  The JOB shall have veto  authority
         over all managed  care,  PPO,  HMO,  Medicare  risk and other  provider
         contracts.



                                    ARTICLE 6

                                      FEES

         6.1      IVP's FEES. IVP shall be paid the following for its Management
Services rendered pursuant to this Agreement:

                  6.1.1             The Cost of Operations; and

                  6.1.2 An Additional  Management Fee, accrued and paid monthly,
         but reconciled to IPSI'S annual results of operations,  equal to 50% of
         the net  income  before tax  (determined  in  accordance  with GAAP and
         without reference to the Additional Management Fee), provided, however,
         that at any time during  which  Capitalization  Loans are  outstanding,
         payment (but not  accrual) of the  Additional  Management  Fee shall be
         limited to Net Available  Cash of IPSI.  "Net  Available  Cash" of IPSI
         shall  mean the amount  resulting  from (a) all  Collections  and other
         income actually  received during the preceding  month;  less the sum of
         (b) all Costs of  Pharmaceutical  Products;  (c) all Cost of Operations
         for such month;  (d) Direct  Costs for such  month;  (e) the payment of
         interest and the repayment, if any, of the current principal portion of
         all  Capitalization  Loans during such month; and (f) a reserve,  in an
         amount determined by the JOB, for anticipated expenses,  capital needs,
         or contingencies of IPSI and for the payment of all applicable  income,
         franchise,   property,  and  payroll  taxes  of  IPSI  for  such  month
         (calculated  after  deduction of expenses of the Additional  Management
         Fee).

         6.2 PRIORITY OF PAYMENTS.  IVP,  IntegraMed,  and IPSI hereby  covenant
that  all  payments  from  accounts  of  IPSI  shall  be paid by IPSI to IVP and
IntegraMed  in the  following  order of  priority:  (a) the  payment of Costs of
Pharmaceutical Products; (b) the payment of Costs of Operations; (c) the payment
of Direct Costs;  (d) the payment or reserve for payment of interest  accrued on
Capitalization  Loans to IVP and IntegraMed (or other lender),  pari passu;  (e)
the payment or reserve for payment of the current portion of the  Capitalization
Loans to IVP and IntegraMed (or other lender),  pari passu;  and (f) the payment
of the  Additional  Management  Fee to IVP  and  the  payment  of  dividends  to
IntegraMed  (not to exceed the  amount of the  Additional  Management  Fee) pari
passu.

                                    ARTICLE 7

                              CAPITALIZATION LOANS

         7.1      CAPITALIZATION LOANS.

                  7.1.1 IVP hereby  covenants  and  agrees to lend to IPSI,  and
         IntegraMed  covenants  and agrees to lend to or to  securing  financing
         from another  source to lend to IPSI,  within five days  following  the
         first meeting of the JOB, 50% of the aggregate funds  determined by the
         JOB  to be  sufficient  and  necessary  to  secure  the  IPSI  pharmacy
         licensure  in the  States in which  the JOB  intends  IPSI to  transact
         business,  to provide initial operating  capital,  and to finance other
         start-up costs identified by the Board (the "Initial Loans"). IVP shall
         have no obligation to transfer such funds to IPSI unless and until IPSI
         delivers  to IVP proof of receipt  of a  matching  amount of funds from
         IntegraMed or another source.  Such Initial Loans shall be evidenced by
         Promissory  Notes  substantially  in the form of Exhibit 7.1.1 attached
         hereto.

                  7.1.2 In the event that, from time to time, the JOB determines
         that IPSI requires  additional  capital to finance  operating  deficits
         and/or capital expenditures of IPSI, IVP hereby covenants and agrees to
         lend to IPSI,  and  IntegraMed  covenants  and  agrees to lend to or to
         securing  financing  from another  source to lend to IPSI,  within five
         days following the meeting of the JOB  authorizing  such loans,  50% of
         the  aggregate  funds  determined  by  the  JOB  to be  sufficient  and
         necessary   to  finance  such   operating   deficits   and/or   capital
         expenditures  ("Subsequent  Loans").  IVP shall have no  obligation  to
         transfer such funds to IPSI unless and until IPSI delivers to IVP proof
         of  receipt of a matching  amount of funds from  IntegraMed  or another
         source.  Such loan shall be evidenced by Promissory Notes substantially
         in the form of Promissory Notes representing the Initial Loans.

                  7.1.3 The  Initial  Loans  and all  Subsequent  Loans,  if any
         (collectively,  the "Capitalization Loans"), shall bear interest at the
         30-Year  Treasury Note rate, and interest shall be paid by IPSI no less
         than annually.  All Capitalization Loans shall be unsecured obligations
         of IPSI,  without a fixed term, and the principal thereon shall be paid
         solely out of Net Profits of IPSI. "Net Profits" of IPSI shall mean the
         amount resulting from the following: (a) all Collections, together with
         other income actually  received,  during the preceding  Fiscal Year (or
         other such other period determined by the JOB); less the sum of (b) all
         costs of  Pharmaceutical  Products sold to IPSI'S Customers during such
         period;  (c) all Cost of  Operations  for such  period;  (d) all Direct
         Costs  for  such   period;   (e)  the   payment  of   interest  on  all
         Capitalization Loans during such period; (f) the payment of, or reserve
         for, all  applicable  income,  property,  and payroll taxes of IPSI for
         such period; and (g) a reserve, in an amount determined by the JOB, for
         anticipated expenses, capital needs, or contingencies of IPSI.



                                    ARTICLE 8

                  EXCLUSIVE MANAGEMENT RIGHT, TERM AND RENEWAL

         8.1 IPSI grants IVP the exclusive  right to manage IPSI during the Term
of this Agreement.

         8.2 The term of this  Agreement  shall begin on the  Effective  Date of
this  Agreement  and shall  expire on the date 10 years after such date  (unless
this  Agreement is renewed from time to time as provided in this Section 8.2) or
on any earlier date if this Agreement is terminated  pursuant to Article 9 below
(the Effective Date through the date of final expiration or termination shall be
referred to as the "Term of this  Agreement").  This Agreement may be renewed by
either party,  if within the period of 180 days prior to the date of expiration,
one party gives notice to the other of its intention to continue this  Agreement
under the same terms and  conditions as set forth herein or under such different
terms and conditions as particularly set forth in the written notice and further
providing  that the other  party has 30 days from the date of notice to  accept,
reject,  or modify the offer. If within 30 days the other party does not respond
or by written notice accepts, this Agreement shall continue for an additional 10
years under the terms and conditions as provided in the notice. In the event the
offer is not accepted, the parties agree to negotiate,  in good faith, a renewal
of this Agreement.






                                    ARTICLE 9

                          TERMINATION OF THE AGREEMENT

         9.1 TERMINATION.  This Agreement may be terminated by any party to this
Agreement in the event of the following, provided, however, that no party having
the right to terminate this Agreement shall be obligated to exercise such right:

                  9.1.1 INSOLVENCY. If a receiver, liquidator, or trustee of any
         party shall be appointed by court  order,  or a petition to  reorganize
         shall be filed against any party under any bankruptcy,  reorganization,
         or insolvency law, and shall not be dismissed within 90 days, or if any
         party shall file a voluntary  petition in bankruptcy or make assignment
         for the  benefit of  creditors,  then  either of the other  parties may
         terminate this Agreement upon 10 days prior written notice to the other
         parties.

                  9.1.2 MATERIAL BREACH.  If any party shall  materially  breach
         its  obligations  hereunder,  then  either  of the  other  parties  may
         terminate  this  Agreement by providing 30 days prior written notice to
         the breaching party  detailing the nature of the breach,  provided that
         the breaching  party shall not have cured the breach within such 30-day
         period,  or, with respect to breaches that are not curable  within such
         30-day period, shall not have commenced to cure such breach within such
         30-day period and  thereafter  shall not have cured the breach with the
         exercise  of due  diligence.  It  shall  be a  material  breach  of the
         obligation to provide Management Services for IVP to provide Management
         Services  in  a  manner  inconsistent  with  the  generally  prevailing
         standard of care in the delivery of pharmacy services to Customers,  or
         to provide Management Services in a commercially unreasonable manner or
         in a manner that wastes or destroys the assets or  reputation  of IPSI.
         IntegraMed  and/or  IPSI shall have the burden of proving  that IVP has
         failed to provide  Management  Services  in a  commercially  reasonable
         manner  or has  destroyed  the  assets  or  reputation  of  IPSI  in an
         arbitration proceeding or court of competent jurisdication.

                  9.1.3  ILLEGALITY.  Any party  may  terminate  this  Agreement
         immediately  upon  receipt  of  notification  by any local,  state,  or
         federal  agency or court of  competent  jurisdiction  that the  conduct
         contemplated  by this  Agreement is forbidden by law;  except that this
         Agreement  shall not  terminate  during  such  period of time as to any
         party that  contests  such  notification  in good faith and the conduct
         contemplated  by this  Agreement  is allowed to  continue  during  such
         contest.  If any governing  regulatory agency asserts that the services
         provided  by any party  under  this  Agreement  are  unlawful  and such
         assertion is not contested by such party (or if contested, the agency's
         assertion is found to be correct by a court of  competent  jurisdiction
         and no appeal is taken,  or if any  appeals  are taken and the same are
         unsuccessful),  this Agreement shall thereupon  terminate with the same
         force as if such termination date was the date originally  specified in
         this  Agreement  as the date of final  expiration  of the terms of this
         Agreement. Notwithstanding this paragraph, the parties acknowledge that
         this  Agreement  serves the interests of all of the parties.  For these
         reasons, the parties agree to make such amendments to this Agreement as
         are  necessary to conform to the  opinions,  reviews,  and/or orders of
         regulatory and/or administrative agencies of any jurisdiction,  such as
         to preserve the legality of this Agreement,  provided that such are not
         to the material financial detriment of any party.

                  9.1.4  TERMINATION  UPON LOSS OF LICENSE.  IPSI may  terminate
         this  Agreement  upon 10 days prior written  notice to IVP should IVP's
         license to practice pharmacy,  in any jurisdiction where Pharmaceutical
         Services are provided to Customers of Medical Practices,  is suspended,
         revoked,  or not  renewed.  Any loss,  revocation,  or failure to renew
         licenses of IVP shall be deemed a material  breach of this Agreement by
         the party or parties  whose  negligence,  fault,  or failure to provide
         necessary information is the primary cause of such loss, revocation, or
         non-renewal.

                  9.1.5 TERMINATION UPON UNPROFITABILITY.  In the event that, at
         any time following the date nine months from the Effective Date of this
         Agreement,  IPSI does not have net income determined in accordance with
         GAAP for any  period  of six  consecutive  months,  then any  party may
         terminate this Agreement upon 30 days prior written notice to the other
         parties.

                  9.1.6  Terminations  pursuant to Sections  9.1.1 through 9.1.3
         and the second  sentence  of Section  9.1.4  inclusive  shall be deemed
         termination for cause  ("Termination for Cause"),  and shall be made by
         delivering a termination notice, detailing the reasons therefor, to the
         non-terminating  party, and providing the opportunity to cure under the
         provisions of Section 9.1.2 above.  Terminations  pursuant to the first
         sentence of Section  9.1.4 or pursuant to Section 9.1.5 shall be deemed
         termination without cause ("Termination without Cause").




                                   ARTICLE 10

                             RIGHTS UPON TERMINATION

         10.1 If this  Agreement is Terminated  for Cause by IPSI or IntegraMed,
then:

                  10.1.1 IPSI shall have the right,  but not the obligation,  to
         sell to IVP (and if exercised by IPSI, IVP shall have the obligation to
         purchase  from  IPSI) all  Dedicated  Assets,  at their net book  value
         determined in accordance with GAAP as of the date of termination.

                  10.1.2 IPSI shall have the right,  but not the obligation,  to
         assume all leases for  Facilities  and Dedicated  Assets (to the extent
         that such leases are not in the name of IPSI),  or if the assumption is
         not permitted, to make all payments to IVP called for under such leases
         and to enjoy uninterrupted use of such Facilities and Dedicated Assets.

                  10.1.3 IPSI shall elect its course of action,  with respect to
         Sections 10.1.1 and 10.1.2 above, by the service of a written notice on
         IVP 30 days prior to the date of termination.

                  10.1.4  Any  and  all  Capitalization  Loans  payable  to IVP,
         outstanding at the date of  termination,  shall be deemed paid in full,
         and no further  payments of interest  and/or  principal shall be due or
         payable thereon.

                  10.1.5 The  provisions  of Articles 11 and 12.1 shall be of no
         force and effect.

                  10.1.6 The license granted by Article 13 shall cease, and IPSI
         shall cease to use any such  Tradename and cease to utilize any written
         materials,  for  delivery  to  Customers  of  Pharmaceutical  Products,
         supplied by IVP.

         10.2     If this Agreement is Terminated for Cause by IVP, then:

                  10.2.1 IVP shall have the right,  but not the  obligation,  to
         purchase  from IPSI  (and if  exercised  by IVP,  IPSI  shall  have the
         obligation  to sell to IVP),  all  Dedicated  Assets  at their net book
         value determined in accordance with GAAP as of the date of termination.

                  10.2.2 IVP shall have the right,  but not the  obligation,  to
         assume  all leases  for  Facilities  and  Dedicated  Assets,  or if the
         assumption  is not  permitted,  to make all payments to IPSI called for
         under such leases and to enjoy uninterrupted use of such Facilities and
         Dedicated Assets.

                  10.2.3 IVP shall elect its course of action,  with  respect to
         Sections 10.2.1 and 10.2.2 above, by the service of a written notice on
         IPSI 30 days prior to the date of termination.

                  10.2.4  Any  and  all  Capitalization  Loans  payable  to IVP,
         outstanding  at the  date  of  termination,  shall  be  paid by IPSI or
         IntegraMed immediately.

                  10.2.5 The  provisions  of Articles 11 and 12.2 shall be of no
         force and effect.

                  10.2.6 The license granted by Article 13 shall cease, and IPSI
         shall cease to use any such  Tradename and cease to utilize any written
         materials,  for  delivery  to  Customers  of  Pharmaceutical  Products,
         supplied by IVP.



         10.3 If this Agreement is Terminated without Cause by any party, then:

                  10.3.1 If IVP is the non-terminating party, then (a) IVP shall
         be  entitled  to  the  immediate   payment  of  any   outstanding   IVP
         Capitalization Loans; (b) the provisions of Section 12.1 shall continue
         to apply for the periods specified therein; and (c) the license granted
         by  Article  13  shall  cease,  and  IPSI  shall  cease to use any such
         Tradename and cease to utilize any written  materials,  for delivery to
         Customers of Pharmaceutical Products, supplied by IVP.

                  10.3.2 If IPSI and IntegraMed are the non-terminating parties,
         then (a) IPSI shall be entitled,  as liquidated  damages,  to an amount
         equal to the aggregate amount of any and all outstanding Capitalization
         Loans (other than IVP's  Capitalization  Loans);  (b) the provisions of
         Section 12.2 shall continue to apply for the periods specified therein;
         and (c) the license  granted by Article 13 shall cease,  and IPSI shall
         cease to use any  such  Tradename  and  cease to  utilize  any  written
         materials,  for  delivery  to  Customers  of  Pharmaceutical  Products,
         supplied by IVP.

                  10.3.3 The terminating  party shall waive the right to payment
         for any outstanding  Capitalization  Loans (or if Capitalization  Loans
         are provided by a source other than  IntegraMed,  a termination by IPSI
         or  IntegraMed  shall  waive the right to payment  for any  outstanding
         Capitalization Loans for such other source).

                  10.3.4 The terminating party shall bear any (a) accounting and
         bookkeeping;  and (b)  severance/vacation  costs  associated  with  any
         Employees which directly result from the termination.



         10.4 In the event that this  Agreement  is  terminated  for any reason,
then IVP shall cease dispensing  Pharmaceutical Products to Customers of IPSI as
of the date of notice of termination, and IVP and IPSI covenant to utilize their
best  efforts,  for a period 90 days prior to the  termination  date and 30 days
thereafter,  or, if the required notice of termination be only 30 days, then for
the notice  period and 90 days  post-termination,  to fully  cooperate  so as to
effect a transition  of the  operation to IPSI,  the  collection of all accounts
receivable  earned as of the  termination  date and the payment of all trade and
accounts  payable  as  of  the  termination  date,  including,   if  applicable,
Capitalization Loans (the "Transition Period"). For any services provided by IVP
during a Transition Period that extend beyond the termination date, IVP shall be
paid a  reasonable  fee to be agreed upon  between  the IVP and IPSI,  but in no
event  shall  such  amount be less than the Cost of  Operations  and  Additional
Management Fee, if any, that would have been earned by IVP during the Transition
Period had the Agreement not so terminated.

                                   ARTICLE 11

                                    INSURANCE

         11.1 IVP, at its own cost, shall secure and carry  insurance,  covering
itself and its employees  providing services under this Agreement in the minimum
amount of $1 million per incident, $3 million in the aggregate, for professional
negligence and general liability.  Such insurance shall name IPSI and IntegraMed
as additional named insureds.  IVP shall also carry a policy of public liability
and property  damage  insurance with respect to the  Facilities  under which the
insurer   agrees  to  indemnify  IPSI  and   IntegraMed,   subject  to  ordinary
deductibles, against all cost, expense, and/or liability arising out of or based
upon any and all claims,  accidents,  injuries, and damages customarily included
within the coverage of such policies of insurance available for IVP. The minimum
limits of liability of such insurance shall be $1 million  combined single limit
covering  bodily  injury  and  property  damage.  IPSI and  IntegraMed  shall be
additional  named  insureds  under  the  terms of such  insurance  coverages.  A
certificate  of insurance  evidencing  such policies  shall be presented to IPSI
within 30 days after the  execution of this  Agreement.  Failure to provide such
certificate(s)  with such  period  shall  constitute  a  material  breach by IVP
hereunder subject to the procedures of Section 9.1.2 above.

         11.2 IVP shall  provide IPSI with written  notice,  at least 10 days in
advance of the Effective Date, of any reduction,  cancellation or termination of
the insurance required to be carried by each hereunder.

                                   ARTICLE 12

                      NON-SOLICITATION AND NON-COMPETITION

         12.1 During the Term of this  Agreement,  and for a period of two years
after the termination thereof (except as provided in Section 10 above),  neither
IntegraMed  nor IPSI shall,  either  individually  or through an affiliate,  (a)
enter into any agreement with another  independent person or entity,  other than
IVP, to provide  Management  Services  substantially  similar to the  Management
Services required under this Agreement;  (b) market or sell any  pharmaceuticals
to any end-user  patients except through IPSI during the Term of this Agreement;
or (c) employ or solicit  for  employment  any  employee  of IVP, or contact any
employee  of IVP for the  purpose of  encouraging  such  employees  to leave the
employment of IVP.






         12.2 During the Term of this  Agreement,  and for a period of two years
after the  termination  thereof  (except as provided  in Section 10 above),  IVP
shall not, either  individually or through an affiliate,  (a) market or sell any
Pharmaceutical  Products to any patients of the Medical Practices except through
IPSI (and subject to the terms of this Agreement),  provided, however, that this
prohibition shall not apply to the Medical Practices  identified on Exhibit 12.2
attached  hereto who had Customers  that had purchased  Pharmaceutical  Products
from IVP prior to the Effective Date of this Agreement; or (b) employ or solicit
for  employment  any Employee of IPSI (other than Employees who are employees of
or shared employees with IVP or independent  contractors),  IntegraMed, or their
affiliates ("IPSI Employees"),  or contact any IPSI Employees for the purpose of
encouraging such employees to leave their employment.

                                   ARTICLE 13

                      Licenses and Confidential Information

          13.1 GRANT OF LICENSE.  During the Term of this Agreement,  IVP hereby
grants  to  IPSI  a  nonexclusive,  personal,  nonassignable,   nontransferable,
royalty-free  license to use the "Cycle Kit" tradename  ("Tradename")  in IPSI'S
business. IPSI hereby acknowledges IVP's exclusive ownership of the Tradename.

         13.2 TRADE SECRETS,  PROPRIETARY  AND  CONFIDENTIAL  INFORMATION.  IPSI
hereby  acknowledges  that it shall  have  access to and  become  familiar  with
certain  management  information  systems,  trade secrets,  and  proprietary and
confidential  information  of IVP, as  described  and  scheduled on Exhibit 13.2
("Confidential Information"). IPSI hereby acknowledges IVP's exclusive ownership
of Confidential  Information and agrees not to use or disclose such Confidential
Information  without  the prior  written  consent of IVP,  which  consent may be
withheld by IVP in its sole and absolute discretion. IPSI shall not photocopy or
otherwise  duplicate any  Confidential  Information of another party without the
prior express  written  consent of the such other party except as is required to
perform services under this Agreement.  All such Confidential  Information shall
remain the  exclusive  property of IVP and shall be  returned to the  proprietor
immediately upon any termination of this Agreement.

                                   ARTICLE 14

                                  MISCELLANEOUS

         14.1  FURTHER  ASSURANCES.  Each party  hereto  agrees to  perform  any
further  acts and to execute  and  deliver  any  further  documents  that may be
reasonably necessary to carry out the provisions of this Agreement.






         14.2 PRIOR AGREEMENTS;  AMENDMENTS. This Agreement and the accompanying
exhibits  represent the entire agreement and understanding of the parties hereto
and supersedes all prior agreements and understandings between the parties as to
the subject  matter  covered  hereunder,  and this Agreement may not be amended,
altered,  changed or  terminated  orally.  No amendment,  alteration,  change or
attempted  waiver of any of the provisions  hereof shall be binding  without the
written  consent  of  all  parties,  and  such  amendment,  alteration,  change,
termination  or waiver shall in no way affect the other terms and  conditions of
this Agreement, which in all other respects shall remain in full force.

         14.3  ASSIGNMENT;  BINDING  EFFECT.  This  Agreement and the rights and
obligations  hereunder may not be assigned  without the prior written consent of
all of the parties,  and any attempted  assignment without such consent shall be
void and of no force and effect. Subject to such limitations on assignment,  the
provisions  of this  Agreement  shall be  binding  upon and  shall  inure to the
benefit of the parties' respective heirs, legal representatives,  successors and
permitted assigns.

         14.4 WAIVER OF BREACH.  The  failure to insist  upon strict  compliance
with any of the terms,  covenants  or  conditions  herein  shall not be deemed a
waiver  of such  terms,  covenants  or  conditions,  nor  shall  any  waiver  or
relinquishment  of any  right  at any one or more  times be  deemed a waiver  or
relinquishment of such right at any other time or times.

         14.5 GOVERNING  LAW. This Agreement  shall be governed by and construed
in  accordance  with the  laws of the  State of New  York.  Any and all  claims,
disputes,  or  controversies  arising under,  out of, or in connection with this
Agreement or any breach thereof,  shall be determined by binding  arbitration in
Washington,  D.C. (hereinafter  "Arbitration").  The party seeking determination
shall subject any such dispute, claim or controversy to the American Arbitration
Association,  Washington,  D.C., and the rules of commercial  arbitration of the
selected entity shall govern.  The Arbitration shall be conducted and decided by
three arbitrators,  unless the parties mutually agree, in writing at the time of
the Arbitration,  to fewer arbitrators.  In reaching a decision, the arbitrators
shall have no  authority to change or modify any  provision  of this  Agreement,
including  any  liquidated  damages  provision.  Each  party  shall bear its own
expenses and one-half the expenses and costs of the arbitrators. Any application
to compel Arbitration, confirm, or vacate an arbitral award or otherwise enforce
this  Section  shall be brought  only in the Courts of the States of New York or
Texas or the United States District Courts for the Southern District of New York
or the Northern District of Texas, to whose jurisdiction for such purposes IPSI,
IntegraMed, and IVP hereby irrevocably consent and submit.

         14.6 SEPARABILITY. If any portion of the provisions hereof shall to any
extent be invalid or  unenforceable,  the  remainder of this  Agreement,  or the
application of such portion or provisions in  circumstances  other than those in
which it is held invalid or unenforceable,  shall not be affected  thereby,  and
each portion or provision of this  Agreement  shall be valid and enforced to the
fullest  extent  permitted by law, but only to the extent the same  continues to
reflect  fairly the intent and  understanding  of the parties  expressed by this
Agreement take as a whole.

         14.7  HEADINGS.  Section and  paragraph  headings  are not part of this
Agreement  and are included  solely for  convenience  and are not intended to be
full or accurate descriptions of the contents thereof.

         14.8 NOTICES.  Any notice hereunder shall have been deemed to have been
given only if in writing and either  delivered in hand or sent by  registered or
certified mail, return receipt requested,  postage prepaid,  or by United States
Express Mail or other commercial  expedited  delivery service,  with all postage
and delivery charges prepaid, to the addresses set forth below:

                  14.8.1            If for IPSI:

                                    Gerardo Canet, President & CEO
                                    IntegraMed Pharmaceutical Services, Inc.
                                    One Manhattanville Road
                                    Purchase, NY 10577-2100

                  14.8.2            If for IVP:

                                    Von L. Best, President & CEO
                                    IVP Pharmaceutical Care, Inc.
                                    2833 Trinity Square Drive
                                    Suite 105
                                    Carrollton, TX 75006

                  14.8.3            If for IntegraMed:

                                    Gerardo Canet, President & CEO
                                    IntegraMed America Inc.
                                    One Manhattanville Road
                                    Purchase, NY 10577-2100


         Either party hereto, by like notice to the other parties, may designate
such other address or addresses to which notice must be sent.

         14.9     INDEMNIFICATION.

                  14.9.1  IVP agrees to  indemnify  and hold  harmless  IPSI and
         IntegraMed,  their  shareholders,  directors,  officers,  employees and
         servants  from any  suits,  claims,  actions,  losses,  liabilities  or
         expenses (including  reasonable  attorney's fees and costs) arising out
         of or in  connection  with any act or failure to act by IVP  related to
         the  performance  of  its  duties  and   responsibilities   under  this
         Agreement.  The  obligations  contained  in this  Section  14.9.1 shall
         survive termination of this Agreement.

                  14.10.2 IPSI and  IntegraMed  each agree to indemnify and hold
         harmless  IVP, its  shareholders,  directors,  officers,  employees and
         servants  from any  suits,  claims,  actions,  losses,  liabilities  or
         expenses (including  reasonable  attorney's fees and costs) arising out
         of or in  connection  with  any  act  or  failure  to act  by  IPSI  or
         IntegraMed   related   to   the   performance   of   its   duties   and
         responsibilities  under this Agreement.  The  obligations  contained in
         this Section 14.9.2 shall survive termination of this Agreement.

         14.11 In the  event of any  claims or suits in which  IVP,  IntegraMed,
and/or IPSI and/or their directors,  officers, employees and servants are named,
each of IVP,  IntegraMed,  and IPSI for their  respective  directors,  officers,
employees  agree  to  cooperate  in the  defense  of such  suit or  claim;  such
cooperation  shall include,  by way of example but not limitation,  meeting with
defense counsel (to be selected by the respective party hereto),  the production
of any documents in his/her possession for review, response to subpoenas and the
coordination of any individual  defense with counsel for the respective  parties
hereto. The respective party shall, as soon as practicable, deliver to the other
copies of any summonses,  complaints, suit letters, subpoenas or legal papers of
any kind,  served  upon such party,  for which such party seeks  indemnification
hereunder.  This  obligation  to  cooperate in the defense of any such claims or
suits shall survive the termination, for whatever reason. of this Agreement.

         14.12 Promptly after the receipt by IPSI or IntegraMed of notice of any
claim or  commencement  of any action or proceeding  subject to  indemnification
delineated in Section 14.9.1 ("asserted liability"),  IPSI or IntegraMed, as the
case may be, will demand such  indemnification  from IVP and proffer the defense
to IVP.  IVP may  thereafter,  at its  option,  assume  such  defense at its own
expense and by its own  counsel.  IVP shall  provide  written  notice to IPSI or
IntegraMed, as the case may be, within 20 days, of its assumption or declination
of such defense. If IVP shall undertake to compromise any asserted liability, it
shall promptly  notify IPSI or IntegraMed,  as the case may be, of its intention
to do so and IPSI or IntegraMed,  as the case may be, agrees to cooperate  fully
and  promptly  with IVP and its  counsel in the  compromise  and  defense of any
asserted  liability.  IVP  shall  not  enter  into any  non-monetary  settlement
hereunder  without the prior written consent of IPSI or IntegraMed,  as the case
may be. Notwithstanding the foregoing,  IPSI or IntegraMed,  as the case may be,
shall have the right to participate in the compromise or defense of any asserted
liability with its own counsel and at its own expense.



         14.13  Promptly  after  the  receipt  by IVP of  notice of any claim or
commencement of any action or proceeding subject to  indemnification  delineated
in Section 14.9.2 ("asserted  liability"),  IVP will demand such indemnification
from IPSI or  IntegraMed,  as the case may be, and  proffer  the defense to such
party. Such party may thereafter,  at its option, assume such defense at its own
expense and by its own counsel.  Such party shall provide written notice to IVP,
within 20 days, of its  assumption or  declination  of such defense.  If IPSI or
IntegraMed,  as the case may be,  shall  undertake  to  compromise  any asserted
liability,  it shall  promptly  notify the IVP of its intention to do so and IVP
agrees  to  cooperate  fully  and  promptly  with  IVP  and its  counsel  in the
compromise  and defense of any asserted  liability.  Neither IPSI nor IntegraMed
shall enter into any non-monetary settlement hereunder without the prior written
consent  of IVP.  Notwithstanding  the  foregoing,  IVP shall  have the right to
participate in the compromise or defense of any asserted  liability with its own
counsel and at its own expense.

         14.14 CONSTRUCTION.  Each party and its counsel have participated fully
in the review and revision of this Agreement.  In construing this Agreement,  it
shall be deemed to have been drafted jointly.


         IN WITNESS  WHEREOF,  this  Agreement  has been executed by the parties
hereto as of the day and year first above written.

IVP PHARMACEUTICAL CARE, INC.



By:      /s/Von L. Best
         -------------------------------
         Von L. Best, President and CEO


INTEGRAMED PHARMACEUTICAL SERVICES, INC.



By:      /s/ Gerardo Canet
         --------------------------------
         Gerardo Canet, President and CEO


INTEGRAMED AMERICA, INC.



By:      /s/Gerardo Canet
         --------------------------------  
         Gerardo Canet, President and CEO





                                   EXHIBIT 0.2

IntegraMed America Inc. Reproductive Science Centers Network

1. Reproductive Science Center of Boston
2. Reproductive Science Associates- Mineola, New York and Stoney Brook, New York
3. Reproductive Science Center of the Bay Area Fertility and Gynecology
   Medical Group
4. Reproductive Science Associates- Kansas City, Missouri
5. Reproductive Science Center at the Walter Reed Army Medical Center
6. Institute of Reproductive Medicine and Science of Saint Barnabas
   Medical Center
7. Fertility Centers of Illinois
8. Shady Grove Fertility Centers





                                  EXHIBIT 1.1.1

                              Cost of Operations
                              (% of Net Revenue)



   --------------------------------------------------------------------------
                Monthly                             Cost Of
              Net Revenue                          Operations
   --------------------------------------------------------------------------
   
             $25,000 Or Below                        22.84%
             $50,000 Or Below                        17.15%
            $100,000 Or Below                        14.30%
            $200,000 Or Below                        12.86%
            $400,000 Or Below                        12.16%
            $800,000 Or Below                        11.81%
          $1,250,000 Or Below                        11.68%
          $1,500,000 Or Below                        11.64%






                                  EXHIBIT 1.1.2

                         Cost of Pharmaceutical Products

         IVP will  purchase  Pharmaceutical  Products and will use its wholesale
license  to  resell to IPSI on a  just-in-time  basis.  IVP will pass  along its
utilization and market-share  rebates to IPSI; however,  IVP will not pass along
its 2% Gonal F special  rebate,  its trade  discounts  received as incentive for
timely  payment,  or its  discounts on bulk  purchases as defined  below.  These
guidelines yield the following rebate structure as of the Effective Date of this
Agreement:

Qualifying Rebates (Passed along to IPSI):
1. The variable Serono market-share rebates and the Serono Gonal F Sales Force
   rebate.
2. The Organon utilization rebates.
3. The Ferring market-share rebates.

Non-Qualifying Rebates (Kept by IVP):
1. All rebates given as incentive for timely payment (e.g., 2% 30/ Net 31).
2. The Serono 2% Gonal F special rebate.

Other Issues:
1. A few manufacturers,  e.g., TAP, do not offer any rebates, and IVP buys
   at Wholesale  Acquisition Cost (WAC).  These products will be billed at
   net invoice +2%.
2. From  time  to  time,  IVP  may  receive   additional   discounts  from
   manufacturers for committing to bulk purchases.  The quantities usually
   represent a three- to 12-month  supply,  and the value of the discounts
   is  partially  offset by IVP's  cost of  capital,  storage  costs,  and
   property taxes. These discounts will not be passed along to IPSI.
3. WAC  will be the  basis  by  which  all  products  are  sold  to  IPSI.
   Qualifying  rebates  that are taken by IVP at time of  payment  will be
   passed to IPSI on IVP's invoice.  Qualifying  rebates that are received
   via check from the  manufacture  at a later time will be estimated  and
   accrued in the IPSI monthly financials.






                                 EXHIBIT 1.1.12

                    Pharmaceutical Products Kept On The Shelf
                                ($15,000 Maximum)

                              2x2  Nonsterile  Gauze
                              Alcohol  Prep Pads
                              Amoxil Cap 500mg
                              Aygestin Tab 5mg
                              Climara Dis 0.05mg
                              Climara Dis 0.1mg
                              Clomid 50mg
                              Clomiphene  Citrate  50mg
                              Demulen 1/35 28 Tabs
                              Dexamethasone Tab 0.25mg
                              Dexamethasone Tab 0.5mg
                              Dexamethasone Tab 0.5mg
                              Doxycycline   Hyclate   Cap  100mg
                              Estrace Tab 0.5mg
                              Estrace Tab 1mg
                              Estrace Tab 2mg
                              Estraderm Dis 0.1mg
                              Estradiol Tab 0.5mg
                              Estradiol  Tab  1mg
                              Estradiol  2mg
                              Folic Acid Tab 1mg
                              Heparin  Sodium DCU Inj 20000ml
                              Heparin Sodium Inj 10000ml
                              Medrol Tab 16mg
                              Medrol  Tab 4mg
                              Medrol  Tab 8mg
                              Methylprednisolone   Tab  4mg
                              Ortho-Novum 1/35 21  Tabs
                              Ortho-Novum  7/7/7  28 Tabs
                              Ovcon 35/21 Tabs
                              Ovu Quick 9 day
                              Ovu Quick 6 day
                              Parlodel Tab 2.5mg
                              Prednisone  Tab 10mg
                              Prednisone  Tab 20mg
                              Prednisone Tab 5mg
                              Prenate  Ultra Tab
                              Serophene Tab 50mg
                              Stuartnatal  Plus  Tab  Plus
                              Synarel  Sol 2mg/ml
                              Tetracycline HCL Cap 500mg
                              Vivelle Dis 0.1mg





                                  EXHIBIT 3.2.1

                        [floor plan to be inserted here]





                                  EXHIBIT 7.1.1

           Form of Promissory Notes Representing Capitalization Loans

                         NON-NEGOTIABLE PROMISSORY NOTE

BORROWER:                      IntegraMed Pharmaceutical Service, Inc.
                                     2833 Trinity Square Drive
                                     Suite 170
                                     Carrollton, Texas 75006

LENDER:                        ________________________________________
                               ________________________________________
                               ________________________________________

                             
PRINCIPAL AMOUNT:              $150,000.00

INDEX:                         30-Year Treasury Bill Rate

INITIAL RATE:                  5.25%

DATE OF NOTE:                  April __, 1999


PROMISE  TO PAY.  Borrower  promises  to pay to Lender,  in lawful  money of the
United  States of America,  the principal  amount of One Hundred Fifty  Thousand
Dollars and Zero Cents ($150,000.00) or so much as may be outstanding,  together
with interest on the unpaid outstanding  principal balance, on December 31, 2009
(the "Maturity Date"), or earlier as provided herein.

DESCRIPTION OF NOTE. This Note represents a  Capitalization  Loan, as defined in
that certain  Management  Agreement  dated April ___, 1999, by and among,  inter
alia, Borrower and Lender (the "Management Agreement").

CHOICE OF USUARY  CEILING AND INTEREST  RATE. The interest rate on this Note has
been  implemented  under the "Indicated  Rate Ceiling" as referred to in Article
5069-1.04(a)(1) of Vernon's Texas Civil Statutes, as amended  ("V.T.C.S.").  The
terms,  including  the rate,  or index,  formula,  or  provision  of law used to
compute  the rate,  on the Note,  will be subject to  revision as to current and
future  balances,  from time to time, by notice from Lender in  compliance  with
Article 5069-1.04(i) V.T.C.S.

PAYMENT.  Except as provided herein, Borrower shall pay this loan in one payment
of all  outstanding  principal plus all accrued unpaid  interest on the Maturity
Date. Borrower shall make regular yearly payments of accrued but unpaid interest
beginning December 31, 1999, and all subsequent interest payments are due on the
same day of each year thereafter. Interest on this Note is computed on a 365/360
simple interest  basis;  i.e., by applying the ratio of the annual interest rate
over a year  of 360  days,  multiplied  by the  outstanding  principal  balance,
multiplied by the actual number of days the  principal  balance is  outstanding,
unless such calculation  would result in a usurious rate, in which case interest
shall be  calculated  on a per diem  basis of a year of 365 or 366 days,  as the
case may be. Borrower will pay Lender at Lender's address shown above or at such
other place as Lender may designate in writing.

MANDATORY  PREPAYMENT.  Borrower shall make mandatory  prepayments  from time to
time equal to a portion of the "Net Profits" of Borrower,  as defined in Section
7.1.3 of the Management  Agreement,  for such periods as Borrower and Lender may
mutually agree from time to time,  such portion to equal the percentage that the
outstanding principal amount of the Capitalization Loan represented by this Note
bears to the outstanding principal amount of all Capitalization Loans subject to
the Management  Agreement.  This Note is also subject to  acceleration,  or this
Note may be deemed paid in full, upon the occurrence of certain events described
in Article 10 of the Management Agreement.

OPTIONAL PREPAYMENT.  Borrower may pay without penalty all or any portion of the
amount owed prior to the Maturity  Date. All  prepayments  will be applied first
against accrued but unpaid  interest and then against the outstanding  principal
balance.



VARIABLE  INTEREST RATE. The interest rate on this Note may be subject to change
from time to time  based on  changes in the  coupon  rate for new  issuances  of
30-Year U.S.  Treasuries  (the  "Index").  Lender  shall inform  Borrower of the
current Index rate upon  Borrower's  request.  The interest rate change will not
occur more frequently than once in any three-month  period.  The Index currently
is 5.25% per annum.  The interest  rate to be applied prior to the Maturity Date
to the unpaid  principal  balance of this Note initially will be at a rate equal
to the  Index,  resulting  in an  Initial  Rate of 5.25%  per  annum,  and shall
thereafter be equal to the greater of the Initial Rate or the Index, adjusted if
necessary for the maximum rate  limitation  described  below.  NOTICE:  Under no
circumstances  will the interest rate on this Note be more than the maximum rate
allowed by applicable  law. For purposes of this Note, the "maximum rate allowed
by  applicable  law"  means  the  lesser  of (a) the  maximum  rate of  interest
permitted under federal or other law applicable to the indebtedness evidenced by
this  Note;  or (b) the  "Indicated  Rate  Ceiling"  as  referred  to in Article
5069-1.04(a)(1) V.T.C.S.

POST-MATURITY DATE RATE. The Post-Maturity Date Rate on this Note is the maximum
rate  allowed by  applicable  law.  Borrower  shall pay interest on all sums due
after the Maturity Date at the Post-Maturity Date Rate.

DEFAULT.  Borrower  will be in default,  unless  waived or deferred by Lender in
writing,  upon the occurrence of any of the following events: (a) Borrower fails
to make any payment when due; (b) Borrower  breaches any  covenant,  obligation,
representation,  or warranty  Borrower has made to Lender,  or Borrower fails to
perform promptly at the time and strictly in the manner provided in this Note or
any agreement  related to this Note, or in any other  agreement or loan Borrower
has with Lender,  including the Management Agreement;  (c) any representation or
statement  made or  furnished to Lender by Borrower or on  Borrower's  behalf is
false or misleading in any material respect;  or (d) Borrower becomes insolvent,
a receiver is appointed for any part of Borrower's  property,  Borrower makes an
assignment for the benefit of creditors,  or any proceeding is commenced  either
by Borrower or against Borrower under any bankruptcy or insolvency laws.

If any  default,  other than a default in payment,  is curable,  it may be cured
(and no event of default  shall have  occurred)  if  Borrower,  after  receiving
written notice from Lender demanding cure of such default: (a) cures the default
within  15 days;  or (b) if the cure  requires  more  than 15 days,  immediately
initiates  steps that  Lender  deems in  Lender's  reasonable  discretion  to be
sufficient  to cure the default  and  thereafter  continues  and  completes  all
reasonable  and  necessary  steps  sufficient  to produce  compliance as soon as
reasonably practical.

LENDER=S  OBLIGATIONS;  THIRD-PARTY  CURE AND  SUBSTITUTION.  In the  event of a
default  in  payment  that is not  waived by  Lender,  or any other  default  by
Borrower  that is not cured  pursuant to the  immediately  preceding  paragraph,
Lender  shall give  written  notice to the  Company,  attention  Gerardo  Canet,
specifying  the type and,  in the case of a default in  payment,  amount of such
default. The Company shall have the right, within 10 days following such written
notice, to cure such default and succeed to all of the rights and obligations of
Borrower under this Note.

LENDER'S RIGHTS. Upon default by Borrower, Lender may, subject to the Management
Agreement,  declare  the entire  indebtedness,  including  the unpaid  principal
balance on this Note, all accrued unpaid interest, and all other amounts, costs,
and  expenses  for which  Borrower is  responsible  under this Note or any other
agreement with Lender pertaining to this loan,  immediately due, without notice,
and Borrower  must pay such amount.  Lender may hire an attorney to help collect
this Note if Borrower  does not pay, and Borrower  will pay Lender's  reasonable
attorneys'  fees.  Borrower  also will pay  Lender  all other  amounts  actually
incurred  by  Lender as court  costs,  lawful  fees for  filing,  recording,  or
releasing to any public office any instrument securing this loan; the reasonable
costs  actually  expended for  repossessing,  storing,  preparing for sale,  and
selling  any  security;  and  fees  for  noting  a  lien  on or  transferring  a
certificate of title to any titled collateral offered as security for this loan,
or premiums or  identifiable  charges  received in  connection  with the sale of
authorized  insurance.  This Note has been  delivered  to Lender and accepted by
Lender in the  State of Texas.  If there is a  lawsuit,  and if the  transaction
evidenced by this Note occurred in Dallas County,  Borrower agrees upon Lender's
request to submit to the jurisdiction of the courts of Dallas County,  the State
of Texas.  Lender and  Borrower  hereby waive the right to any jury trial in any
action, proceeding, or counterclaim brought by either Lender or Borrower against
the other.  This Note shall be governed by and construed in accordance  with the
laws of the State of Texas and applicable federal laws.



GENERAL PROVISIONS.  If any part of this Note cannot be enforced, this fact will
not affect  the  enforceability  of the rest of the Note.  In  particular,  this
provision  means (among other  things) that Borrower does not agree or intend to
pay, and Lender does not agree or intend to contract for, charge, collect, take,
reserve,  or receive  (collectively  referred to herein as "charge or collect"),
any  amount in the nature of  interest  or in the nature of a fee for this loan,
which would in any way or event (including demand,  prepayment, or acceleration)
cause  Lender to  charge or  collect  more for this loan than the  maximum  rate
allowed by applicable law. Any such excess  interest or unauthorized  fee shall,
instead of  anything  stated to the  contrary,  be  applied  first to reduce the
principal balance of this loan, and when the principal has been paid in full, be
refunded to Borrower.  The right to accelerate all sums due under this Note does
not include the right to accelerate any interest that has not otherwise  accrued
on the date of such  acceleration,  and  Lender  does not  intend  to  charge or
collect any  unearned  interest in the event of  acceleration.  All sums paid or
agreed to be paid to Lender for the use,  forbearance,  or detention of sums due
hereunder  shall,  to the extent  permitted  by  applicable  law, be  amortized,
prorated,  allocated,  and spread throughout the full term of the loan evidenced
by this Note  until  payment in full so that the rate or amount of  interest  on
account  of the loan  evidence  hereby  does not exceed  the  applicable  usuary
ceiling. Lender may delay or forgo enforcing any of its rights or remedies under
this Note  without  losing  them.  Borrower  and any  other  person  who  signs,
guarantees,  or  endorses  this  Note,  to the  extent  allowed  by  law,  waive
presentment,  demand for payment,  protest, notice of dishonor, notice of intent
to  accelerate  this Note,  and notice of  acceleration  of this Note.  Upon any
change in the terms of this  Note,  and  unless  otherwise  expressly  stated in
writing,   no  party  who  signs  this  Note,   whether  as  maker,   guarantor,
accommodation  maker, or endorser,  shall be released from  liability.  All such
parties agree that Lender may renew or extend  (repeatedly and for any length of
time) this loan,  or release any party or  guarantor or  collateral;  or impair,
fail to realize upon, or perfect  Lender's  security  interest in the collateral
without the consent or notice to anyone. All such parties also agree that Lender
may modify this loan  without the consent of or notice to anyone  other than the
party with whom the modification is made.

SECURITY.  This Note is unsecured.

       IN  WITNESS  WHEREOF,  I have set my hand  hereto  as of the  date  first
written above.

                                          BORROWER:



                                          /s/Gerardo Canet
                                          --------------------------------
                                          Gerardo Canet, President and CEO





                                  EXHIBIT 12.2

                IVP's Prior Relationships with Medical Practices


1.       Reproductive Science Center of Boston
2.       Shady Grove Reproductive Science Centers, Inc.
3.       Institute of Reproductive Medicine and Science of Saint
         Barnabas Medical Center






                                  EXHIBIT 13.2

         IVP's Trade Secrets, Proprietary, and Confidential Information


1.    All information related to IVP that is not directly related to IPSI.
2.    IVP retail pricing structure.
3.    All internal policies and procedures used by IVP.
4.    IVP's rebate structure with all pharmaceutical drug manufacturers
      and distributors.
5.    IVP's business plans and strategies.
6.    IVP's customer relationships,  referral sources,  payors, and patients. 7.
      IVP's  dispensing  and drug  utilization  data.  8. IVP's  trade names and
      programs developed for its direct-to-patient distribution services. 9. Any
      other material, programs, or systems that IVP deems as confidential.