EXHIBIT 99.1

                  SECTION 906 CERTIFICATION OF PERIODIC REPORT

I, Michael A. Martino, President and Chief Executive Officer of Sonus
Pharmaceuticals, Inc. (the "Company"), certify, pursuant to Section 906 of the
Sarbanes-Oxley Act of 2002, 18 U.S.C. Section 1350, that:

(1)    the Quarterly Report on Form 10-Q of the Company for the quarterly period
       ended March 31, 2003 (the "Report") fully complies with the requirements
       of Section 13(a) or 15(d) of the Securities Exchange Act of 1934 (15
       U.S.C. 78m or 780(d)); and

(2)    the information contained in the Report fairly presents, in all material
       respects, the financial condition and results of operations of the
       Company.

Dated: May 14, 2003

                                           /s/ Michael A. Martino
                                           -------------------------------------
                                           Michael A. Martino
                                           President and Chief Executive Officer