Exhibit 4


                           EMMET, MARVIN & MARTIN, LLP

                               COUNSELLORS AT LAW


                                                         177 MADISON AVENUE
                              120 BROADWAY          MORRISTOWN, NEW JERSEY 07960
                                                           (973) 538-5600
WRITER'S DIRECT DIAL    NEW YORK, NEW YORK 10271         FAX: (973) 538-6448
                                 _____
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                                 _____          STAMFORD, CONNECTICUT 06902-4543
                                                           (203) 425-1400
                          FAX: (212) 238-3100            FAX: (203) 425-1410
                      http://www.emmetmarvin.com


                                                June 7, 2004

The Bank of New York
  as Depositary
101 Barclay Street
New York, New York, 10286

Re:   American Depositary Receipts for Ordinary Shares, Nominal Value 2 Euro per
      Share, of Sanofi-Synthelabo


Ladies and Gentlemen:

         We refer to the  registration  statement  to be filed on Form F-6 under
the  Securities Act of 1933 (the  "Registration  Statement") by the legal entity
created by the  agreement  (the  "Deposit  Agreement")  for issuance of American
Depositary Shares ("ADSs")  evidenced by American  Depositary  Receipts ("ADRs")
ordinary shares,  nominal value 2 euro per share, of Sanofi-Synthelabo for which
you propose to act as Depositary.

         We are  of the  opinion  that  the  ADSs  covered  by the  Registration
Statement,  when issued in accordance  with the terms of the Deposit  Agreement,
will,  when sold, be legally issued and will entitle the holders  thereof to the
rights specified in the Deposit Agreement and the ADRs.

         This  opinion  may be used  by you as an  exhibit  to the  Registration
Statement.

                                                Very truly yours,

                                                /s/ EMMET, MARVIN & MARTIN, LLP
                                                -------------------------------

                                                EMMET, MARVIN & MARTIN, LLP