UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549

                                    FORM 8-K

                                 CURRENT REPORT
     Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934

       Date of Report (Date of earliest event reported): November 8, 2004

                                  Icoria, Inc.
             (Exact name of registrant as specified in its charter)

           Delaware                  0-30365                     56-2047837
(State or other jurisdiction       (Commission                (I.R.S. Employer
      of incorporation)            File Number)              Identification No.)

                 108 T.W. Alexander Drive,
         Research Triangle Park, North Carolina                   27709
        (Address of principal executive offices)                  (Zip Code)

       Registrant's telephone number, including area code: (919) 425-3000

                             Paradigm Genetics, Inc.
          (Former name or former address, if changed since last report)

Check  the  appropriate  box  below  if the  Form  8-K  filing  is  intended  to
simultaneously  satisfy the filing obligation of the registrant under any of the
following provisions (see General Instruction A.2. below):

|_|   Written  communications  pursuant to Rule 425 under the Securities Act (17
      CFR 230.425)

|_|   Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR
      240.14a-12)

|_|   Pre-commencement  communications  pursuant  to  Rule  14d-2(b)  under  the
      Exchange Act (17 CFR 240.14d-2(b))

|_|   Pre-commencement  communications  pursuant  to  Rule  13e-4(c)  under  the
      Exchange Act (17 CFR 240.13e-4(c))



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ITEM 2.02 RESULTS OF OPERATIONS AND FINANCIAL CONDITION.

      On November 8, 2004,  Icoria,  Inc. (the "Company" or "ICOR") Nasdaq(R) NM
issued a press release  announcing  its financial  results for the third quarter
ended  September  30, 2004. A copy of the press  release is furnished as Exhibit
99.1 to this report and is incorporated herein by reference.

      This  information  shall not be deemed to be "filed"  for the  purposes of
Section 18 of the Securities  and Exchange Act of 1934 (the "Exchange  Act") and
shall not be deemed incorporated by reference in any filing under the Securities
Act of 1933 or the  Exchange  Act,  except as  expressly  set forth by  specific
reference in such a filing.


ITEM 5.02   DEPARTURE OF DIRECTORS OR PRINCIPAL OFFICERS; ELECTION OF
            DIRECTORS; APPOINTMENT OF PRINCIPAL OFFICERS.

      (b) On November 8, 2004,  Philip R. Alfano,  the Company's Vice President,
Finance, Chief Financial Officer and Treasurer announced,  for personal reasons,
his intention to step down from his current position with the Company  effective
December 31, 2004.  Until the  effective  date,  Mr. Alfano will continue in his
current role with the Company.  Thereafter,  both he and the Company intend that
he remain  employed  on a  part-time  basis,  as Special  Assistant  to the CEO,
involved in special projects.

ITEM 7.01 REGULATION FD DISCLOSURE.


      On the  November  8, 2004  conference  call,  the  Company  discussed  its
contract with Bayer AG ("Bayer"),  and the Company's  belief that Bayer is going
to  exercise  its  right to wind the  contract  down in early in 2005 due to the
availability of their internal  resources for assay  development.  The impact of
this potential development was discussed in more detail on that call.

      This  information  shall not be deemed to be "filed"  for the  purposes of
Section 18 of the Securities  and Exchange Act of 1934 (the "Exchange  Act") and
shall not be deemed incorporated by reference in any filing under the Securities
Act of 1933 or the  Exchange  Act,  except as  expressly  set forth by  specific
reference in such a filing.


ITEM 9.01. FINANCIAL STATEMENTS AND EXHIBITS

      (c)   Exhibits:

            99.1  Press Release of Icoria, Inc. dated November 8, 2004


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                                   SIGNATURES

Pursuant  to the  requirements  of the  Securities  Exchange  Act of  1934,  the
registrant  has duly  caused  this  report  to be  signed  on its  behalf by the
undersigned hereunto duly authorized.

                                                 ICORIA, INC.

                                                 (Registrant)

Dated: November 9, 2004                      By: /s/ Philip R. Alfano
                                                 ------------------------------
                                                 Philip R. Alfano
                                                 Vice President, Finance, Chief
                                                 Financial Officer and Treasurer


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                                  EXHIBIT INDEX


Exhibit
  No.        Description
- -------      -----------
99.1         Press Release of Icoria, Inc. dated November 8, 2004


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