As filed with the Securities and Exchange Commission on November 13, 1998 Registration No. 33-95894 ================================================================================ SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 --------------- POST EFFECTIVE AMENDMENT NO. 1 TO FORM S-8 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 IMCLONE SYSTEMS INCORPORATED (Exact name of registrant as specified in its charter) Delaware 04-2834797 (State or other jurisdiction of (I.R.S. Employer incorporation or organization) Identification No.) 180 Varick Street New York, New York 10014 (Address of Principal Executive Offices) (Zip Code) ImClone Systems Incorporated 1986 Non-Qualified Stock Option Plan, As Amended ImClone Systems Incorporated 1986 Incentive Stock Option Plan Certain Warrants to Purchase Shares of Common Stock (Full title of the plan) --------------------------- John B. Landes, Esq. Vice President, Business Development and General Counsel ImClone Systems Incorporated 180 Varick Street New York, New York 10014 (Name and address of agent for service) (212) 645-1405 (Telephone number, including area code, of agent for service) Copy to: Lawrence A. Darby III, Esq. Kaye, Scholer, Fierman, Hays & Handler, LLP 425 Park Avenue New York, New York 10022-3598 ================================================================================ On August 24, 1995, ImClone Systems Incorporated (the "Company") filed a registration statement on Form S-8 (Registration No. 33-95894) with the Securities and Exchange Commission. The registration statement registered a total of 4,090,220 shares of the Company=s Common Stock issuable under options issued or issuable under the ImClone Systems Incorporated 1986 Incentive Stock Option Plan, the ImClone Systems Incorporated 1986 Non-Qualified Stock Option Plan, and under certain stand-alone warrants issued by the Company to certain persons (the "Warrants"). The Company hereby requests that 751,500 of the shares that remain subject to the Warrants be deregistered. 2 SIGNATURES Pursuant to the requirements of the Securities Act of 1933, the Registrant certifies that it has reasonable grounds to believe that it meets all of the requirements for filing on Form S-8 and has duly caused this Registration Statement to be signed on its behalf by the undersigned, thereunto duly authorized, in the City of New York, State of New York, on the 13th day of November, 1998. IMCLONE SYSTEMS INCORPORATED By:________________________________*_ Samuel D. Waksal President and Chief Executive Officer Pursuant to the requirements of the Securities Act of 1933, this Registration Statement has been signed below by the following persons in the capacities and on the dates indicated. Signature Title Date --------- ----- ---- _________________________* Chairman of the Board November 13, 1998 Robert F. Goldhammer and Director _________________________* President, Chief Executive November 13, 1998 Samuel D. Waksal Officer and Director (Principal Executive Officer) _________________________* Executive Vice President, Chief November 13, 1998 Harlan W. Waksal Operating Officer and Director _________________________ Vice President of Finance and November 13, 1998 Carl Goldfischer Chief Financial Officer (Principal Financial and Accounting Officer) _________________________* Director November 13, 1998 Jean Carvais _________________________* Director November 13, 1998 Vincent T. DeVita, Jr. _________________________* Director November 13, 1998 Paul B. Kopperl _________________________ Director November 13, 1998 William R. Miller _________________________ Director November 13, 1998 David M. Kies _________________________ Director November 13, 1998 Richard Barth _________________________ Director November 13, 1998 John Mendelsohn * By: /s/ John B. Landes ------------------- John B. Landes Attorney-In-Fact