SECURITIES AND EXCHANGE COMMISSION

                             Washington, D.C. 20549

                                    FORM 8-K

                                 CURRENT REPORT

     Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934

         Date of Report (Date of earliest event reported) June 21, 2001

                                   ENZON, INC.
             (Exact name of registrant as specified in its charter)

          Delaware                      0-12957                    22-2372868
(State or other jurisdiction          (Commission                 (IRS Employer
      of incorporation)               File Number)               Identification)


                20 Kingsbridge Road, Piscataway, New Jersey 08854
               (Address of principal executive offices) (Zip Code)



       Registrant's telephone number, including area code: (732) 980-4500



                                       NA
          (Former name or former address, if changed since last report





Item 5. Other Events

     Enzon, Inc. announced today the private placement of $400 million principal
amount of 4 1/2% Convertible  Subordinated  Notes due 2008. The offering,  which
was made through initial purchasers to qualified institutional buyers under Rule
144A of the Securities Act of 1933, as amended, is expected to close on June 26,
2001.  Enzon has also granted the initial  purchasers  of the notes an option to
purchase up to an additional $60 million in principal  amount of the notes.  The
notes are convertible  into Enzon common stock, at a conversion  price of $70.98
per share,  subject to adjustment in certain events.  Enzon has agreed to file a
registration statement for the resale of the notes and the common stock issuable
upon conversion of the notes within 90 days after the closing of the offering.

     Enzon  intends  to use the  proceeds  of the  sale  for  general  corporate
purposes,  including  its internal  discovery and  development  programs and the
development of new  technologies,  general  working  capital and possible future
acquisitions.

     The securities have not been  registered  under the Securities Act of 1933,
as amended, and, unless so registered,  may not be offered or sold in the United
States,  except  pursuant  to an  applicable  exemption  from  the  registration
requirements  of the  Securities Act of 1933, as amended,  and applicable  state
securities laws.

     This shall not constitute an offer to sell or the  solicitation of an offer
to buy  any of  these  securities.  This  is  being  issued  pursuant  to and in
accordance with Rule 135c under the Securities Act of 1933, as amended.

     Except for the historical information herein, the matters discussed in this
Form 8-K include  forward-looking  statements that may involve a number of risks
and uncertainties.  Actual results may vary significantly based upon a number of
factors which are described in the Company's Form 10-K, Form 10-K/A,  Form 10-Qs
and Form  8-Ks on file  with the SEC,  including  without  limitation,  risks in
obtaining  and  maintaining  regulatory  approval for  indications  and expanded
indications, market acceptance of and continuing demand for Enzon's products and
the impact of competitive products and pricing.





                                   SIGNATURES

     Pursuant to the  requirements  of the Securities  Exchange Act of 1934, the
Registrant  has duly  caused  this  report  to be  signed  on its  behalf by the
undersigned hereunto duly authorized.

Dated: June 21, 2001

                                                    ENZON, INC.
                                     -------------------------------------------
                                                   (Registrant)




                                 By:  /s/ KENNETH J. ZUERBLIS
                                     -------------------------------------------
                                     Kenneth J. Zuerblis
                                     Vice President, Finance and Chief Financial
                                        Officer