================================================================================

                                  UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549

                                    FORM 11-K

               [X] ANNUAL REPORT PURSUANT TO SECTION 15(d) OF THE
                         SECURITIES EXCHANGE ACT OF 1934

                   For the fiscal year ended December 31, 2000

                                       OR

          [ ] TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE
                         SECURITIES EXCHANGE ACT OF 1934

                         Commission file number 0-23975

A.   FULL TITLE OF THE PLAN AND THE ADDRESS OF THE PLAN, IF DIFFERENT  FROM THAT
     OF THE ISSUER NAMED BELOW:

                         First Niagara Bank 401(k) Plan
                      6950 South Transit Road P.O. Box 514
                          Lockport, New York 14095-0514

B.   NAME OF THE  ISSUER OF THE  SECURITIES  HELD  PURSUANT  TO THE PLAN AND THE
     ADDRESS OF ITS PRINCIPAL EXECUTIVE OFFICE:

                       First Niagara Financial Group, Inc.
                      6950 South Transit Road P.O. Box 514
                          Lockport, New York 14095-0514

REQUIRED INFORMATION

      The First  Niagara  Bank 401(k) Plan (the  "Plan") is subject to ERISA and
      therefore is filing the  financial  statements  and  schedule  prepared in
      accordance with the financial  reporting  requirements of ERISA, as of and
      for the years  ended  December  31,  2000 and 1999,  as an exhibit to this
      report. Such Plan financial statements and schedule include an Independent
      Auditors' Report thereon.

EXHIBIT INDEX

     23   Consent of KPMG LLP

     99   First Niagara Bank 401(k) Plan Financial Statements and Schedule as of
          and for the years ended December 31, 2000 and 1999,  with  Independent
          Auditors' Report thereon.

SIGNATURES

      Pursuant to the  requirements of the Securities  Exchange Act of 1934, the
      Compensation Committee of the Board of Directors of First Niagara Bank (as
      administrator  of the Plan) has caused this annual  report to be signed on
      its behalf by the undersigned hereunto duly authorized.

                                          First Niagara Bank 401(k)


Date:  June 27, 2001                      By:/s/  Kathleen P. Monti
     ---------------------------             -----------------------------------
                                                  Kathleen P. Monti
                                                  Executive Vice President
                                                  Chief Administrative Officer

================================================================================