SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. __ ) Filed by the Registrant [X] Filed by a Party other than the Registrant [ ] Check the appropriate box: [ ] Preliminary Proxy Statement [X] Definitive Proxy Statement [ ] Definitive Additional Materials [ ] Soliciting Material pursuant to Rule 14a-11(c) or Rule 14a-12 ENZON, INC. (Name of Registrant as Specified In Its Charter) KEVIN T. COLLINS,ESQ. (Name of Person(s) filing Proxy Statement) Payment of Filing Fee (Check the appropriate box): [ ] $125 per Exchange Act Rules 0-11(c)(1)(ii), 14a-6(I)(1), or 14a-6(j)(2). [ ] $500 per each party to the controversy pursuant to Exchange Act Rule 14a-6(I)(3). [ ] Fee computed on table below per Exchange Act Rules 14a-6(I)(4) and 0-11. (1) Title of each class of securities to which transaction applies: ---------------------------------------------------------------------- (2) Aggregate number of securities to which transaction applies: ---------------------------------------------------------------------- (3) Per unit price or other underlying value of transaction computed pursuant to Exchange Act Rule 0-11: (4) Proposed maximum aggregate value of transaction: ---------------------------------------------------------------------- Set forth the amount on which the filing fee is calculated and state how it was determined. [ ] Check box if any part of the fee is offset as provided by Exchange Act rule 0-11(a)(2) and identify the filing for which the offsetting fee was paid previously. Identify the previous filing by registration statement number, or the Form or Schedule and the date of its filing. 1) Amount Previously Paid: ---------------------------------------------------------------------- 2) Form, Schedule or Registration Statement No.: ---------------------------------------------------------------------- 3) Filing Party: ---------------------------------------------------------------------- 4) Date Filed: ---------------------------------------------------------------------- [LOGO] ENZON, INC. 20 Kingsbridge Road Piscataway, New Jersey 08854 (732) 980-4500 NOTICE OF ANNUAL MEETING OF STOCKHOLDERS TO BE HELD DECEMBER 1, 1998 To our Stockholders: You are hereby notified that the annual meeting of stockholders (the "Annual Meeting") of Enzon, Inc., a Delaware corporation ("Enzon" or the "Company") will be held at the Embassy Suites Hotel, 121 Centennial Avenue, Piscataway, New Jersey on Tuesday, December 1, 1998 at 10:00 a.m. local time, for the following purposes: 1. To elect two Class III directors, each for a term of three years in accordance with the Company's Certificate of Incorporation and By-Laws (Proposal No. 1); 2. To vote on a proposal to approve amendments to the Company's Non-Qualified Stock Option Plan, as amended (Proposal No. 2); 3. To ratify the selection of KPMG Peat Marwick LLP, independent certified public accountants, to audit the consolidated financial statements of the Company for the fiscal year ending June 30, 1999 (Proposal No. 3); and 4. To transact such other matters as may properly come before the Annual Meeting or any adjournment thereof. Only holders of record of the Company's Common Stock, par value $.01 per share, and Series A Cumulative Convertible Preferred Stock, par value $.01 per share, at the close of business on October 27, 1998 are entitled to notice of, and to vote at the Annual Meeting. Enzon hopes that as many stockholders as possible will personally attend the Annual Meeting. WHETHER OR NOT YOU PLAN TO ATTEND THE ANNUAL MEETING, YOUR PROXY VOTE IS IMPORTANT. TO ASSURE YOUR REPRESENTATION AT THE MEETING, PLEASE COMPLETE, SIGN AND DATE THE ENCLOSED PROXY CARD AND RETURN IT PROMPTLY IN THE ENCLOSED ENVELOPE. Sending in your proxy will not prevent you from voting in person at the Annual Meeting. By order of the Board of Directors, John A. Caruso, Secretary Piscataway, New Jersey October 28, 1998 ENZON, INC. ------- PROXY STATEMENT ------- This Proxy Statement is furnished in connection with the solicitation of proxies for use at the annual meeting of stockholders (the "Annual Meeting ") to stockholders of record of Enzon, Inc. ("Enzon" or the "Company") to be held on Tuesday, December 1, 1998 and at any adjournment thereof. The accompanying proxy is solicited by the Board of Directors of the Company and is revocable by the stockholder any time before it is voted. For more information concerning the procedure for revoking the proxy see "General." This Proxy Statement was first mailed to stockholders of the Company on or about November 2, 1998, accompanied by the Company's Annual Report to Stockholders for the fiscal year ended June 30, 1998. The principal executive offices of the Company are located at 20 Kingsbridge Road, Piscataway, New Jersey 08854, telephone (732) 980-4500. OUTSTANDING SHARES AND VOTING RIGHTS Only holders of the Company's common stock, par value $.01 per share (the "Common Stock" or "Common Shares") and Series A Cumulative Convertible Preferred Stock, $.01 per share (the "Series A Preferred Stock" or "Series A Preferred Shares") outstanding at the close of business on October 27, 1998 (the "Record Date") are entitled to receive notice of and vote at the Annual Meeting. As of the Record Date, the number and class of stock that was outstanding and will be entitled to vote at the meeting were 35,409,969 Common Shares and 107,000 Series A Preferred Shares. Each Common Share and Series A Preferred Share is entitled to one vote on all matters. No other class of securities will be entitled to vote at the Annual Meeting. There are no cumulative voting rights. To be elected, a director must receive a plurality of the votes of the Common Shares and Series A Preferred Shares, voting as a single class, present in person or represented by proxy at the Annual Meeting and entitled to vote on the election of directors. The affirmative vote of at least a majority of the Common Shares and Series A Preferred Shares, present in person or represented by proxy at the Annual Meeting and entitled to vote thereon, voting together as a single class, is necessary for approval of Proposal No. 2 and Proposal No. 3. A quorum is representation in person or by proxy at the Annual Meeting of at least one-third of the combined Common Shares and Series A Preferred Shares outstanding as of the Record Date. Pursuant to the Delaware General Corporation Law, only votes cast "For" a matter constitute affirmative votes. Proxy cards which are voted by marking "Withheld" or "Abstain" on a particular matter are counted as present for quorum purposes and for purposes of determining the outcome of such matter, but since they are not cast "For" a particular matter, they will have the same effect as negative votes or votes cast "Against" a particular matter. If a validly executed proxy card is not marked to indicate a vote on a particular matter and the proxy granted thereby is not revoked before it is voted, it will be voted "For" such matter. Where brokers are prohibited from exercising discretionary authority for beneficial owners who have not provided voting instructions (commonly referred to as "broker non-votes"), such broker non-votes will be treated as shares that are present for purposes of determining the presence of a quorum; however, with respect to proposals which require the affirmative vote of a percentage of shares present at the Annual Meeting for approval, such broker non-votes will be treated as not present for purposes of determining the outcome of any such matter. With respect to proposals which require the affirmative vote of a percentage of the outstanding shares for approval, since such broker non-votes are not cast "For" a particular matter, they will have the same effect as negative votes or votes cast "Against" such proposals. 1 PROPOSAL NO. 1 - ELECTION OF DIRECTORS Pursuant to the provisions of the Company's Certificate of Incorporation and By-laws, the Board of Directors is comprised of three classes of directors, designated Class I, Class II and Class III. One class of directors is elected each year to hold office for a three-year term and until successors of such directors are duly elected and qualified. Two Class III directors will be elected at this year's Annual Meeting. The nominees for election to the office of director, and certain information with respect to their backgrounds and the backgrounds of non-nominee directors, are set forth below. It is the intention of the persons named in the accompanying proxy card, unless otherwise instructed, to vote to elect the nominees named herein as Class III directors. Each of the nominees named herein presently serves as a director of the Company. In the event any of the nominees named herein is unable to serve as a director, discretionary authority is reserved to the Board of Directors to vote for a substitute. The Board of Directors has no reason to believe that any of the nominees named herein will be unable to serve if elected. Nominees for Election to the Office of Director at the 1998 Annual Meeting Director Nominee Age Since Position with the Company - ------- --- ----- ------------------------- Rolf A. Classon(2) 53 1997 Director Robert LeBuhn(2)(3) 66 1994 Director Non-Nominee Directors Continuing to Serve in the Office of Director After the 1998 Annual Meeting Director Nominee Age Since Position with the Company - ------- --- ----- ------------------------- Peter G. Tombros(1)(4) 56 1994 President and Chief Executive Officer Randy H. Thurman(1)(5) 49 1993 Chairman of the Board Dr. Rosina B. Dixon(2)(4) 55 1994 Director Dr. David W. Golde(5) 58 1998 Director A.M. "Don" MacKinnon(1)(3)(5) 73 1990 Director (1) Member of the Executive Committee (2) Member of the Compensation Committee (3) Member of the Audit Committee (4) Class I director serving until the 1999 Annual Meeting (5) Class II director serving until the 2000 Annual Meeting 2 BUSINESS EXPERIENCE OF DIRECTORS Nominee Class III Directors for Election at the 1998 Annual Meeting Rolf A. Classon has served as a Director of the Company since January 1997. Mr. Classon is currently an Executive Vice President of Bayer Corporation and President of Bayer Diagnostics. From 1991 to 1995, Mr. Classon was an Executive Vice President in charge of Bayer Diagnostics' Worldwide Marketing, Sales and Service operations. From 1990 to 1991, Mr. Classon was President and Chief Operating Officer of Pharmacia Biosystems A.B. Prior to 1991, Mr. Classon served as president of Pharmacia Development Company Inc. and Pharmacia A.B. Hospital Products Division. Robert LeBuhn has served as a Director of the Company since August 1994. Mr. LeBuhn was chairman of Investor International (U.S.), Inc., a subsidiary of Investor A.B., part of Sweden's Wallenberg Group from June 1992 until his retirement in September 1994, and was its president from August 1984 through June 1992. Mr. LeBuhn is a director of US Airways Group, Inc., Acceptance Insurance Companies, Inc. and Cambrex Corporation. He is president and a trustee of the Geraldine R. Dodge Foundation. The Board of Directors recommends a vote FOR Mr. Classon and Mr. LeBuhn as Class III Directors (Proposal No. 1 on the Proxy Card). Non-Nominee Class I Directors Serving Until the 1999 Annual Meeting Peter G. Tombros has served as President and Chief Executive Officer of the Company and a member of the board since April 1994. Prior to joining Enzon, Mr. Tombros spent 25 years with Pfizer Inc., a research based, global healthcare company headquartered in New York City. From 1986 to March 1994, he served as a vice president of Pfizer Inc. in the following areas: executive vice president of Pfizer Pharmaceuticals, a division of Pfizer Inc., corporate strategic planning and investor relations. From 1980 to 1986, Mr. Tombros served as senior vice president of Pfizer Pharmaceuticals and general manager for the Roerig division of Pfizer Inc. Mr. Tombros currently serves on the Board of Trustees of Cancer Care and the National Cancer Care Foundation, Dominican College and Fisk University. From 1980 to 1992, he was a director of the American Foundation of Pharmaceutical Education and served as Chairman for three of those years. Mr. Tombros serves on the Board of Directors of NPS Pharmaceuticals Inc. and Alpharma Inc. Dr. Rosina B. Dixon has served as a Director of the Company since August 1994. Dr. Dixon has been a consultant to the pharmaceutical industry since 1987. Prior to such time she held senior positions at Ciba-Geigy Pharmaceuticals, a division of Ciba-Geigy Corporation, and Schering-Plough Corporation. She received her M.D. from Columbia University, College of Physicians and Surgeons and is certified by the National Board of Medical Examiners and the American Board of Internal Medicine. She is a member of the American College of Clinical Pharmacology, American Society for Clinical Pharmacology and Therapeutics and the National Association of Corporate Directors and currently serves as a director of Church & Dwight Co., Inc. and Cambrex Corporation. Non-Nominee Class II Director Serving Until the 2000 Annual Meeting Randy H. Thurman has served as the Chairman of the Board of the Company since April 1996 and as a Director of the Company since April 1993. Mr. Thurman is Chairman and Chief Executive Officer of Strategic Reserves, LLC, a company he founded in 1996. Mr. Thurman is the founder and has been Chairman of the Board of Health Care Strategies 2000, a global healthcare consulting firm, since 1995. During 1996, Mr. Thurman also served as a principal of Spencer Stuart Inc. From 1993 to 1995, Mr. Thurman served as Chairman and Chief Executive Officer of Corning Life Sciences. From 1985 to 1993, Mr. Thurman served as Corporate Executive Vice President and a Director of Rhone-Poulenc Rorer, Inc. and President of Rhone-Poulenc Rorer Pharmaceuticals, Inc. He also serves on the Board of Directors of Closure Medical, Inc. 3 A.M. "Don" MacKinnon has served as a Director of the Company since 1990. Mr. MacKinnon was president and chief operating officer of Ciba-Geigy Corporation from 1980 until his retirement in 1986. He was a member of the Board of Directors of Ciba-Geigy Corporation from 1970 until he reached the mandatory retirement age in December 1994. Over the last nine years, Mr. MacKinnon has served on the Board of Directors of several biopharmaceutical companies. Dr. David W. Golde has served as a Director of the Company since March 1998. Dr. Golde has been the Physician-In-Chief at Memorial Sloan-Kettering Cancer Center since 1996. From 1991 to 1996, Dr. Golde served as Head of the Division of Hematology and Oncology at Memorial Sloan-Kettering Cancer Center. Prior to 1991, Dr. Golde was a professor of medicine and Chief of the Division of Hematology and Oncology at UCLA, Director of the UCLA AIDS Center and Director of the UCLA Clinical Research Center. DIRECTORS' COMPENSATION Directors' Cash Compensation During the fiscal year ended June 30, 1998, the Company paid Randy H. Thurman $100,000 in consideration for serving as Chairman of the Board. The Company did not pay cash compensation to its remaining directors for acting as directors or as members of committees of the Board of Directors, other than reimbursement of reasonable expenses incurred by the directors in attending board and committee meetings. Directors' Stock Options In December 1993, the Board of Directors adopted, and the stockholders approved, an amendment to the Non-Qualified Stock Option Plan, as amended, (the "Plan") providing for automatic grants of options ("Automatic Grants") under a formula (the "Formula") to non-executive members of the Board of Directors ("Independent Directors"). Under the Formula, Independent Directors automatically receive an option to purchase 60,000 shares of Common Stock on each of the following dates: January 2, 1994, January 2, 1997, January 2, 2000 and January 2, 2003 (the "Regular Grants"). On the date of each Independent Director's initial election to the board, pursuant to a vote of the Company's stockholders or the board, such newly-elected Independent Director automatically receives (i) an option to purchase such Independent Director's pro rata share of the Regular Grant, which equals the product of 1,666 multiplied by the number of whole months remaining in the relevant three year period until the next Regular Grant (the "Pro Rata Grant"); and (ii) an option to purchase 10,000 shares of Common Stock (the "Initial Election Grant"). Each option granted to an Independent Director pursuant to a Regular Grant vests and becomes exercisable as follows: as to 20,000 shares one year after the date of grant; as to 20,000 shares two years after the date of grant, and as to the remaining 20,000 shares three years after the date of grant. Those options granted pursuant to a Pro Rata Grant vest and become exercisable as to that number of shares equal to the product of 1,666 multiplied by the number of whole months remaining in the first calendar year in which the Independent Director is elected initially to the board on the January 1st following such Independent Director's initial election to the board; and as to any remaining shares in accordance with the schedule for options granted pursuant to a Regular Grant. Those options granted pursuant to an Initial Election Grant vest and become exercisable as to 5,000 shares one year after the date of grant; and as to 5,000 shares two years after the date of grant. The per share exercise price of options granted pursuant to the Formula is equal to the fair market value of the Common Stock on the date of grant. An option granted to an Independent Director pursuant to the Formula will not become exercisable as to the relevant shares unless such Independent Director has served continuously on the board during the year preceding the date on which such options are scheduled to vest and become exercisable, or from the date such Independent Director joined the board until the end of such year should such Independent Director have joined the board during such year; provided, however, that if an Independent Director does not fulfill such continuous service requirement due to such Independent Director's death or disability all options granted under the Formula and held by such Independent Director nonetheless vest and become exercisable as though such Independent Director fulfilled the continuous 4 service requirement. An option granted to an Independent Director pursuant to the Formula remains exercisable for a period of ten years from the date of grant. For a discussion of proposed amendments to the Plan, which will affect options granted to Independent Directors, see Proposal No. 2 Independent Directors' Stock Plan The Company's 1996 Independent Directors' Stock Plan (the "Independent Directors' Stock Plan") provides compensation to Independent Directors serving on the board which is paid in the form of the Company's Common Stock. Other than the Chairman of the Board, Independent Directors are not currently entitled to receive cash compensation. Under the Independent Directors' Stock Plan, each Independent Director is entitled to compensation in the form of shares of common stock of the Company with a value equal to $2,500 per quarter and $500 for each meeting attended by the board member. The number of shares issued will be based on the last reported sale price of a share of Common Stock on the NASDAQ National Market at the end of the quarter for which fees are payable. During the year ended June 30, 1998, the Company recorded $71,834 in Independent Directors' fees. The following is a summary of compensation paid to the Independent Directors under the Independent Director's Stock Plan: Value of Number Consideration of Shares ------------- --------- Randy H. Thurman $13,500 2,325 Rolf A. Classon 12,000 2,058 Dr. Rosina Dixon 14,000 2,404 David W. Golde 4,334 672 Robert LeBuhn 14,000 2,404 A.M. "Don" MacKinnon 14,000 2,404 Section 16(a) Beneficial Ownership Reporting Compliance Ownership of and transactions in the Company's stock by executive officers and directors of the Company and owners of 10% or more of the Company's outstanding Common Stock are required to be reported to the Securities and Exchange Commission pursuant to Section 16(a) of the Securities Exchange Act of 1934, as amended. During the year ended June 30, 1998, all such reports were filed in a timely manner. INFORMATION CONCERNING BOARD AND COMMITTEE MEETINGS AND COMMITTEES OF THE BOARD Eight meetings of the Company's Board of Directors were held during the fiscal year ended June 30, 1998. Rolf A. Classon attended four of the eight Board of Directors meetings held. With the exception of Mr. Classon, each incumbent director attended at least 75% of the total number of meetings of the Board of Directors. All incumbent directors attended at least 75% of the total number of meetings of any committees of the Board of Directors, of which such director was a member, held during the fiscal year. As of June 30, 1998, the only standing committees of the Company's Board of Directors were the Audit Committee, Compensation Committee and Executive Committee. The Audit Committee is comprised of Robert LeBuhn, Chairman, and A.M. "Don" MacKinnon. The primary functions of the Audit Committee are to meet with the Company's independent auditors to discuss and review audit procedures and issues, meet with management on matters concerning the Company's financial condition, internal controls and year-end audit and report to the board on such matters. The Audit Committee held two meetings during the fiscal year ended June 30, 1998. 5 The Compensation Committee is comprised of Dr. Rosina B. Dixon, Chairperson, Rolf A. Classon and Robert LeBuhn. The primary functions of the Compensation Committee are to administer the Company's Non-Qualified Stock Option Plan, determine the compensation of the Company's officers and senior management and review compensation policy. There were four meetings of the Compensation Committee during the fiscal year ended June 30, 1998. The Executive Committee, comprised of A.M. "Don" MacKinnon, Chairman, Peter G. Tombros, and Randy H. Thurman, was established to review and make decisions concerning matters which would otherwise come before the Board, as permitted by Delaware General Corporate Law and the Company's by-laws. Given the relatively small size of the Company's current Board of Directors, the Company determined that efficiencies were not being realized from meetings of the Executive Committee and therefore suspended regular meetings of the Executive Committee in September 1994. There were no meetings of the Executive Committee during the fiscal year ended June 30, 1998. COMPENSATION COMMITTEE INTERLOCKS AND INSIDER PARTICIPATION As of the date hereof, the members of the Board of Directors serving on the Compensation Committee of the Board of Directors are Dr. Rosina B. Dixon, Chairperson, Dr. Rolf A. Classon and Robert LeBuhn, all of whom are non-employee directors of the Company. BUSINESS EXPERIENCE OF EXECUTIVE OFFICERS Set forth below is certain information regarding the executive officers of the Company who do not serve on the Board of Directors. John A. Caruso, 53, has served as Vice President, Administration since May 1998, General Counsel of the Company since July 1994 and as Secretary of the Company since July 1989. From January 1991 to May 1998, Mr. Caruso served as Vice President of Business Development. From January 1991 to July 1994, Mr. Caruso served as Vice President, Legal Affairs of the Company. From the time he joined the Company in September 1987 through December 1990, Mr. Caruso served as Corporate Counsel to the Company. From 1979 through 1987, Mr. Caruso was employed at Baxter Travenol Laboratories in Deerfield, Illinois as corporate counsel. Kenneth J. Zuerblis, 39, has served as Chief Financial Officer since January 1996 and as Vice President, Finance since April 1994. From July 1991 to April 1994, Mr. Zuerblis served as the Company's Controller. From January 1982 to July 1991, Mr. Zuerblis was employed by KPMG Peat Marwick LLP. He became a certified public accountant in 1985. 6 SUMMARY COMPENSATION TABLE The following table provides a summary of cash and non-cash compensation for each of the last three fiscal years ended June 30, 1998, 1997 and 1996 with respect to Enzon's Chief Executive Officer and the other executive officers serving during the fiscal year ended June 30, 1998 (the "Named Executive Officers"). Annual Compensation Long-Term ------------------------------- Compensation Awards ----------- Securities Name and Other Annual Underlying All Other Principal Position Year Salary($) Bonus($) Compensation($)(1) Options(#) Compensation($)(2) ------------------ ---- --------- -------- ------------------ ---------- ------------------ Peter G. Tombros 1998 $336,000 $ 70,560 $ -- 78,000(5) $ 5,000 President and Chief 1997 307,626 50,000(4) -- 420,000 4,729 Executive Officer 1996 300,000 -- 36,000(3) 60,000 950 John A. Caruso 1998 171,642 $ 26,025 -- 90,000(5) -- Vice President, Administration, 1997 170,000 25,000 -- 80,000 163 General Counsel and Secretary 1996 163,651 39,100 -- 40,000 -- Kenneth J. Zuerblis 1998 154,692 $ 33,600 -- 110,000(5) 3,775 Vice President, Finance and 1997 148,052 40,000 -- 90,000 5,395 Chief Financial Officer 1996 132,813 24,871 -- 40,000 1,989 (1) Excludes perquisites and other personal benefits that in the aggregate do not exceed 10% of the Named Executive Officer's total annual salary and bonus. (2) Consists of annual Company contributions to a 401(k) plan. (3) Consists of auto and living allowance. As of April 5, 1997, the Company ceased paying Mr. Tombros an auto and living allowance. (4) The payment of Mr. Tombros' bonus, earned for the year ended June 30, 1997, was deferred at his option. (5) Includes stock options granted during July 1998, which represent a portion of the Named Executive Officer's total bonus earned for the year ended June 30, 1998. 7 OPTION GRANTS IN LAST FISCAL YEAR The following table contains information concerning the grant of stock options under the Company's Non-Qualified Stock Option Plan to the Named Executive Officers during the fiscal year ended June 30, 1998. Individual Grants ------------------------------------------------ Number of Potential Realizable Value at Assumed Securities % of Total Annual Rates of Stock Price Underlying Options Granted Appreciation for Option Term (3) Options to Employees Exercise or Base Expiration ------------------------------------ Name Granted (1) in Fiscal Year Price ($/Share) Date 0%($) 5%($) 10%($) - ---- ----------- -------------- --------------- ---- ----- ----- ------ John A. Caruso 40,000(2) 7.07% $6.00 12/02/07 0 $150,935 $382,498 Kenneth J. Zuerblis 40,000(2) 7.07% 6.00 12/02/07 0 150,935 382,498 (1) All options were granted at an exercise price that equaled or exceeded the fair market value of the Common Stock on the date of grant, as determined by the last sale price as reported on the NASDAQ National Market. The options will become exercisable as to all shares immediately upon a "change in control" of the Company as defined in certain agreements between the executive officers and the Company. See "Employment and Termination Agreements". (2) These options will vest and become exercisable as to 50% of the shares granted on December 2, 1998 and 50% on December 2, 1999, provided that the Named Executive Officer is employed by the Company on the vesting date. (3) The amounts set forth in the three columns represent hypothetical gains that might be achieved by the optionees if the respective options are exercised at the end of their terms. These gains are based on assumed rates of stock price appreciation of 0%, 5% and 10% compounded annually from the dates the respective options were granted. The 0% appreciation column is included because the options were granted with exercise prices which equaled or exceeded the market price of the underlying Common Stock on the date of grant, and thus will have no value unless the Company's stock price increases above the exercise prices. 8 OPTION EXERCISES AND FISCAL YEAR-END VALUES The following table sets forth the information with respect to the Named Executive Officers concerning the exercise of options during the fiscal year ended June 30, 1998 and unexercised options held as of June 30, 1998. Number of Securities Value of Unexercised Underlying Unexercised In-the-Money Options Options at FY-End (#) at FY-End ($)(1) Shares Acquired Value ----------------------------- ------------------------------ Name On Exercise (#) Realized($) Exercisable Unexercisable Exercisable Unexercisable ---- ---------------- ----------- ----------- ------------- ----------- ------------- Peter G. Tombros -- $ -- 909,000 160,000 $2,669,063 $590,000 John A. Caruso 30,000 117,813 190,992 80,000 565,813 162,500 Kenneth J. Zuerblis 30,000 117,813 165,000 85,000 499,375 180,313 (1) Based upon a market value of $6.38 as determined by the last sale price as reported on the NASDAQ National Market on June 30, 1998. If the exercise price is equal to or greater than such last sale price, the option is deemed to have no value. EMPLOYMENT AND TERMINATION AGREEMENTS The Company has a three-year employment agreement with Mr. Tombros, which terminates in April 2000, pursuant to which he receives an annual base salary of $336,000. In the event Mr. Tombros' employment is terminated for any reason, except if such employment is terminated (i) voluntarily by Mr. Tombros (other than in response to the Company's prior material breach of the employment agreement), (ii) by the Company "for cause" (as defined in the employment agreement) or (iii) as a result of Mr. Tombros' death or disability, Mr. Tombros will be entitled to receive his base salary for one year after such termination. In the event Mr. Tombros' employment is terminated due to his death or disability his base salary will be paid for six months subsequent to such termination. Pursuant to his employment agreement, Mr. Tombros was granted a ten-year option under the Company's Non-Qualified Stock Option Plan to purchase 300,000 shares of the Company's Common Stock at a per share exercise price of $2.69, the fair market value of the Company's Common Stock on the date of grant. The vesting and exercisability of the options granted accelerated in 100,000 share increments when the closing stock price of the Company's common stock, exceeded $4, $5 and $6 per share, for at least twenty consecutive trading days as reported by the NASDAQ National Market. Mr. Tombros' employment agreement also requires him to maintain the confidentiality of Company information and assign inventions to the Company. Mr. Tombros is precluded from competing with the Company during the term of his employment agreement and for two years after his employment is terminated if his employment is terminated by the Company for cause or by Mr. Tombros voluntarily (except in response to the Company's prior material breach of the employment agreement). The Company has agreements with each of its executive officers which provide for payment to each executive officer of three years of compensation and benefits (as defined in such agreements) following a change in control of the Company (as defined in such agreements), including the provision for such payment in the event such executive officer's employment with the Company is terminated under certain circumstances following such change in control. Upon a change in control of the Company, all options held by such executive officers shall vest immediately, notwithstanding any vesting provisions in the option certificates or any plan covering such options. The term of these agreements is for three years. Prior to a change in control of the Company, the agreements automatically renew on each successive anniversary for an additional three years, unless the Company gives the executive officer 60 days notice prior to the anniversary date that it does not plan to renew such contracts. 9 REPORT OF THE COMPENSATION COMMITTEE OF THE BOARD OF DIRECTORS The Compensation Committee of the Board of Directors consists of three non-employee directors and determines all compensation paid or awarded to the Company's executive officers, including the Named Executive Officers in the Summary Compensation Table. As with many other biotechnology companies, Enzon's current level of development and the highly volatile nature of biotechnology stocks in general makes executive compensation which is based on sales and earnings goals or stock performance impracticable. The Compensation Committee believes that an important factor in Enzon's success is the continued development and maintenance of a culture focused on team-oriented performance. In this context, compensation has been based on the accomplishment of a blend of mutually shared and individual goals. The Compensation Committee has reviewed the executive compensation of other biotechnology companies with comparable levels of stockholders' equity and development and has designed the Company's total executive compensation to be targeted at the median of executive compensation levels of these companies. The compensation of the Company's executive officers consist of three principal components: (i) base salary and benefits, (ii) a bonus based on individual contributions evaluated against annual goals and (iii) long-term incentives in the form of stock option grants. For the fiscal year ended June 30, 1998, the Compensation Committee instituted a formal Performance Incentive Program for its executive officers and other members of senior management. The structure and design of the program was based on a detailed study of compensation programs provided at comparable biotechnology companies. Under the program, Mr. Tombros can earn a cash bonus of up to a maximum of 35% of his base salary and receive stock option grants to purchase Common Stock of up to a maximum of 130,000 shares. The other executive officers, Mr. Caruso and Mr. Zuerblis, can each earn a cash bonus of up to a maximum of 30% of their base salary and stock option grants to purchase Common Stock of up to a maximum of 100,000 shares of Common Stock. The amount of bonus paid and options granted under the plan is based upon the achievement of predetermined corporate and individual objectives. Stock options granted under the plan are granted with exercise prices equal to the fair market value of the Company's Common Stock on the date of grant. The annual salary of $336,000 and the bonus awarded to the Company's President and Chief Executive Officer for the fiscal year ended June 30, 1998 were based on Mr. Tombros' extensive prior experience as a senior executive of a major multinational pharmaceutical firm and the compensation paid to chief executive officers with similar credentials at comparable biotech companies. The bonus paid to Mr. Tombros under the Company's Performance Incentive Program was based on many factors including the strengthening of the Company's financial position, increasing the awareness of the Company to the financial community, as well as the progress made by the Company and its partners on products in the Company's development pipeline. During the fiscal year ended June 30, 1998, the Compensation Committee awarded cash bonuses under the plan described above to the Company's other executive officers, Messrs. Caruso and Zuerblis. The bonuses were based on the executives' contributions to the improvement of the Company's financial position. The Company also adjusted the salary level of Mr. Caruso and Mr. Zuerblis. The salary adjustments were based on a detailed compensation study of executives with similar credentials at comparable biotechnology companies. In addition to the option granted under the Performance Incentive Program, described above, during the fiscal year ended June 30, 1998, the Compensation Committee granted options to purchase an aggregate of 80,000 shares of Common Stock to Messrs. Caruso and Zuerblis. These options were granted for the purpose of encouraging these executive officers to remain with the Company and to provide a long-term performance incentive to such officers. The options were granted with exercise prices that equaled or exceeded the fair market value of the Company's Common Stock on the date of grant. The options generally require the executive officers to remain with the Company for two years in order for the options to be fully exercisable. THE COMPENSATION COMMITTEE Dr. Rosina B. Dixon, Chairperson Rolf A. Classon Robert LeBuhn 10 STOCKHOLDER RETURN PERFORMANCE GRAPH The graph below summarizes the total cumulative return experienced by the Company's stockholders from June 30, 1993 through June 30, 1998, compared to the NASDAQ National Market Index and a Peer Group index consisting of: Isis Pharmaceuticals, Inc., Repligen Corp., Celgene Corp., Gensia Pharmaceuticals Inc., Collagen Corp., Liposome Inc., Cytel Corp., Cytogen Corp., DNAP Holding Corp., (formerly DNA Plant Technology Corp.) and Cephalon Inc. (the "Peer Group"). The Company and the companies comprising the Peer Group are biotechnology companies which are all traded on the NASDAQ National Market. The Peer Group used for the stockholder return performance graph does not include Synergen Inc., Cambridge Biotech Corporation, or Calgene, Inc. which were included in the Peer Group in prior years. Synergen Inc., and Calgene, Inc. were acquired and are no longer publicly traded. Cambridge Biotech Corporation is no longer traded on the NASDAQ National Market. The changes for the periods shown in the graph and table below are based on the assumption that $100 had been invested in Enzon, Inc. Common Stock and in each index below on June 30, 1993. COMPARISON OF FIVE YEAR CUMULATIVE TOTAL RETURN AMONG ENZON, INC., THE NASDAQ NATIONAL MARKET-US INDEX AND A PEER GROUP [THE FOLLOWING TABLE WAS REPRESENTED BY A LINE CHART IN THE PRINTED MATERIAL.] Fiscal year ending June 30, ------------------------------------------------ 1993 1994 1995 1996 1997 1998 ---- ---- ---- ---- ---- ---- Enzon, Inc. 100 56 49 72 46 131 Peer Group 100 58 71 96 60 47 NASDAQ Stock Market-US 100 101 135 173 210 278 11 SECURITY OWNERSHIP OF CERTAIN BENEFICIAL OWNERS AND MANAGEMENT The following table sets forth certain information concerning stock ownership of all persons known by the Company to own beneficially 5% or more of the outstanding shares of the Company's voting stock, each Director, each Executive Officer named in the Summary Compensation Table and all Executive Officers and Directors of the Company as a group as of October 19, 1998: Percentage of Directors, Officers or Number of Voting Stock 5% Stockholders(1) Shares(2) Outstanding(3) ------------------ --------- -------------- Peter G. Tombros 1,066,300 (4) 2.9% Randy H. Thurman 224,937 (5) * Rolf A. Classon 30,175 (6) * Dr. Rosina B. Dixon 101,680 (7) * Dr. David W. Golde 110,272 (8) * Robert LeBuhn 106,798 (9) * A.M. "Don" MacKinnon 161,616(10) * John A. Caruso 231,292(11) * Kenneth J. Zuerblis 211,600(12) * Clearwater Fund IV Ltd. 2,832,831(13) 7.9% P.O. Box 662 Tortola, British Virgin Islands State of Wisconsin 2,521,000(14) 7.1% Investment Board P.O. Box 7842 Madison, Wisconsin 53707 All Executive Officers and Directors 2,244,670(15) 5.9% as a group (nine persons) - ---------- * Less than one percent. (1) The address of all current Executive Officers and Directors listed above is in the care of the Company. (2) All shares listed are Common Stock. Except as discussed below, none of these shares are subject to rights to acquire beneficial ownership, as specified in Rule 13d-3(d)(1) under the Securities Exchange Act of 1934, as amended, and the beneficial owner has sole voting and investment power, subject to community property laws where applicable. (3) Gives effect to 35,409,969 shares of Common Stock and 108,000 shares of Series A Preferred Stock which were issued and outstanding as of October 19, 1998. Generally, the Series A Preferred Stock and Common Stock will vote as one class of stock. Each share of Common Stock and each share of Series A Preferred Stock is entitled to one vote. The percentage of voting stock outstanding for each stockholder is calculated by dividing (i) the number of shares deemed to be beneficially held by such stockholder as of October 19, 1998 by (ii) the sum of (A) the number of shares of Common Stock outstanding as of October 19, 1998 plus (B) the number of shares of Series A Preferred Stock outstanding as of October 19, 1998 plus (C) the number of shares issuable upon exercise of options or warrants held by such stockholder which were exercisable as of October 19, 1998 or which will become exercisable within 60 days after October 19, 1998. (4) Includes 1,039,000 shares subject to options which were exercisable as of October 19, 1998 or which will become exercisable within 60 days after October 19, 1998. 12 (5) Consists of 200,000 shares subject to options which were exercisable as of October 19, 1998 or which will become exercisable within 60 days after October 19, 1998. (6) Includes 25,000 shares subject to option which were exercisable as of October 19, 1998 or which will become exercisable within 60 days after October 19, 1998. (7) Includes 76,664 shares subject to options which were exercisable as of October 19, 1998 or which will become exercisable within 60 days after October 19, 1998. (8) Includes 72,800 shares held by a separate corporation for Dr. Golde's retirement, 2,800 shares held by three separate trusts for Dr. Golde's children and 1,000 shares beneficially owned by Dr. Golde's wife. (9) Includes 76,664 shares subject to options which were exercisable as of October 19, 1998 or which will become exercisable within 60 days after October 19, 1998. (10) Includes 132,000 shares subject to options which were exercisable as of October 19, 1998 or which will become exercisable within 60 days after October 19, 1998 and 11,800 shares beneficially owned by Mr. MacKinnon's wife. Mr. MacKinnon disclaims beneficial ownership as to the shares owned by his wife. (11) Consists of 230,992 shares subject to options which were exercisable as of October 19, 1998 or which will become exercisable within 60 days after October 19, 1998. (12) Includes 210,000 shares subject to options which were exercisable as of October 19, 1998 or which will become exercisable within 60 days after October 19, 1998 and 600 shares owned by Mr. Zuerblis' IRA. (13) Includes warrants to purchase 273,723 shares of the Company's Common Stock at $4.11 per share and warrants to purchase 200,000 shares at $5.63 per share. The information concerning the Stock ownership of the Clearwater Fund IV Ltd. was obtained from a schedule 13D filed with the Securities and Exchange Commission dated February 28, 1997. (14) The information concerning the stock ownership of the State of Wisconsin Investment Board was obtained from a schedule 13F filed by the State of Wisconsin Investment Board with the Securities and Exchange Commission for the period ended June 30, 1998. (15) Includes all shares owned beneficially by the directors and executive officers named in the Summary Compensation table. 13 PROPOSAL NO. 2 - APPROVAL OF AMENDMENT TO THE NON-QUALIFIED STOCK OPTION PLAN In November 1987, the Company's Board of Directors adopted the Non-Qualified Stock Option Plan (the "Plan") in order to enable the Company to attract and retain qualified employees, directors and independent consultants. Subject to stockholder approval, the Board of Directors has approved an amendment to the Plan to reflect changes described below. The following summary description of the Plan is qualified in its entirety by the full text of the Plan which may be obtained by the Company's stockholders upon request to the Secretary of the Company. The last sale price of a share of the Company's Common Stock as reported by the NASDAQ National Market on October 19, 1998 was $6.00. Basic Terms Under the Plan, directors, officers and employees of the Company and independent consultants to the Company have been, and will be, eligible for grants of options to purchase shares of Common Stock. To date, all options granted under the Plan have been awarded at the discretion of the Board of Directors or a committee thereof or pursuant to the formulas described below. Currently, the Compensation Committee of the Board of Directors determines who will receive options under the Plan, the number of shares of Common Stock which will be issuable upon exercise of options which are granted under the Plan and the terms of the options granted under the Plan to the extent the terms are not otherwise set forth in the Plan. Currently, no option granted under the Plan may be transferred by the optionee, otherwise than by will or the laws of descent and distribution and, generally, during the optionee's lifetime, the option may be exercised only by the optionee. The exercise price of the options must be at least equal to the fair market value of the underlying Common Stock as of the date of grant. Either the Compensation Committee of the Board of Directors or the Board of Directors may, in its discretion, provide that an option may not be exercised in whole or in part for any specified period or periods of time. No option may be exercised prior to six months from the date of grant except immediately prior to the dissolution or liquidation of the Company or a merger or consolidation where the Company is not the surviving corporation, in which case all outstanding options become immediately exercisable. Options expire no later than the tenth anniversary of the date of grant. Automatic Awards To Independent Directors The Plan provides that Independent Directors receive option grants pursuant to a formula (the "Formula"). The Formula provides that on each of January 2, 1994, January 2, 1997, January 2, 2000 and January 2, 2003, each of the Company's Independent Directors will automatically receive an option to purchase 60,000 shares of Common Stock (the "Regular Grant"). On the date of each Independent Director's initial election to the board, pursuant to a vote of the Company's stockholders or the board, such newly-elected Independent Director will automatically receive (i) an option to purchase such Independent Director's pro rata share of the Regular Grant, which will equal the product of 1,666 multiplied by the number of whole months remaining in the relevant three year period until the next Regular Grant (the "Pro Rata Grant"); and (ii) an option to purchase 10,000 shares of Common Stock (the "Initial Election Grant"). Each option granted to an Independent Director pursuant to the Formula will vest and become exercisable as follows: those options granted pursuant to a Regular Grant will vest and become exercisable as to 20,000 shares one year after the date of grant; as to 20,000 shares two years after the date of grant; and as to the remaining 20,000 shares three years after the date of grant. Those options granted pursuant to a Pro Rata Grant will vest and become exercisable as to that number of shares equal to the product of 1,666 multiplied by the number of whole months remaining in the first calendar year in which the Independent Director is elected initially to the board on the January 1st following such Independent Director's initial election to the board; and as to any remaining shares in accordance with the schedule for options granted pursuant to a Regular Grant. Those options granted pursuant to an Initial Election Grant will vest and become exercisable as to 5,000 shares one year after the date of grant; and as to 5,000 shares two years after the date of grant. 14 An option granted to an Independent Director pursuant to the Formula will not become exercisable as to the relevant shares unless such Independent Director has served continuously on the board during the year preceding the date on which such options are scheduled to vest and become exercisable, or from the date such Independent Director joined the board until the end of such year should such Independent Director have joined the board during such year; provided, however, that if an Independent Director does not fulfill such continuous service requirement due to such Independent Director's death or disability, all options granted under the Formula and held by such Independent Director shall nonetheless vest and become exercisable as though such Independent Director fulfilled the continuous service requirement. An option granted to an Independent Director pursuant to the Formula will remain exercisable for a period of ten years from the date of grant. Administration The Plan is to be administered by either the Board of Directors or a committee of at least two directors appointed by the board. The Plan is currently administered by the Compensation Committee. Amendments and Termination Currently, no options may be granted under the Plan beyond November 21, 2007. The Compensation Committee or the Board of Directors may terminate, amend, or revise the Plan with respect to any shares as to which options have not been granted, but may not alter any previously granted options without the optionee's consent. Termination of the Plan will not affect previously granted options. Subject to the foregoing restriction relating to outstanding options, the Board can amend the Plan without stockholder approval unless stockholder approval is required by applicable law or the rules of Nasdaq or any stock exchange on which the Company's shares are then traded. Capital Adjustments The aggregate number of shares of Common Stock available for options, the shares subject to any option, and the price per share, will all be proportionately adjusted for any increase or decrease in the number of issued shares of Common Stock resulting from (1) a subdivision or consolidation of shares or any other capital adjustment, (2) the payment of a stock dividend on the Company's Common Stock, or (3) other increase or decrease in such shares effected without receipt of consideration by the Company. If the Company shall be the surviving corporation in any merger or consolidation, any option outstanding under the Plan shall pertain, apply, and relate to the securities to which a holder of the number of shares of Common Stock subject to the option would have been entitled after the merger or consolidation. Upon dissolution or liquidation of the Company, or upon a merger or consolidation in which the Company is not the surviving corporation, all options outstanding under the Plan shall terminate; except that each optionee shall have the right, immediately prior to such dissolution or liquidation, or such merger or consolidation, to exercise the options that such optionee holds in whole or in part. Tax Consequences An optionee will not recognize taxable income for Federal income tax purposes upon the receipt of an option under the Plan, and the Company will not be entitled to a deduction upon the grant of an option. Upon exercise of an option, the optionee will recognize ordinary income equal to the excess of the fair market value on the date of exercise of the Common Stock received upon exercise over the exercise price for such Common Stock. However, any such optionee who is subject to the trading restrictions of Section 16(b) of the Exchange Act would, unless the optionee elected to recognize ordinary income on the date of exercise, recognize ordinary income on the date such trading restrictions terminate (the "Deferred Date"). The amount of such income would equal the excess of the fair market value on the Deferred Date of the Common Stock received upon exercise of the option over the exercise price for such Common Stock, and the holding period for long-term capital gain treatment would not begin until the Deferred Date. The Company will be entitled to a deduction equal to the amount of ordinary income recognized by any optionee at the same time that such optionee recognized such income. 15 Eligible Participants As of October 19, 1998, there were approximately 100 persons eligible to participate in the Plan. Of these eligible participants, seven are members of the Board of Directors (six of whom are Independent Directors), six are members of the Company's Scientific Advisory Board who are not board members, two are executive officers who are not board members and the remainder are employees of the Company who are not executive officers and consultants. Proposed Amendments to the Plan The Board is proposing two amendments to the Plan. These amendments are designed to provide greater flexibility to participants in the Plan, thereby enhancing the Plan's incentive to participants. Under the Plan, as currently in force, options may not be transferred other than under the laws of decent or distribution. This restriction on transferability of options was required based on previous regulations promulgated under Section 16(b) of the Securities Exchange Act of 1934, as amended. Due to changes in such regulations, however, options may now be transferred by participants in stock option plans. The first proposed amendment would align the Plan with current regulations and provide greater flexibility to participants by removing the current restriction on the transferability of options granted under the Plan, to permit the exercise of options, at the discretion of the Compensation Committee, by transferees or beneficiaries who are family members or spouses of an optionee. If approved, this proposed amendment would permit an optionee to, in a manner established by the Compensation Committee, transfer options or designate a family member or spouse as beneficiary or beneficiaries to exercise the rights of the Plan participant and receive any property distributable with respect to any option granted under the Plan. Notwithstanding this proposed amendment, no option may be pledged, alienated, attached or otherwise encumbered, and any purported pledge, alienation, attachment of encumbrance thereof shall be void and unenforceable against the Company. In addition, under the current Plan, participants who exercise stock options must pay the Company such exercise price in cash on the delivery of the underlying shares of Common Stock then owned by the optionee. The second amendment would permit, at the discretion of the Compensation Committee, the "cashless exercise" of options under the Plan by permitting optionees who exercise an option to surrender that number of shares of Common Stock of the Company subject to such option with an aggregate fair market value equivalent to the aggregate exercise price of the exercised option in lieu of cash payment of the exercise price. For information concerning options granted under the Plan to directors, the Chief Executive Officer and the Named Executive Officers see "Directors' Compensation - Directors' Stock Options," "Summary Compensation Table" and "Option Grants In Last Fiscal Year." The Board of Directors recommends a vote FOR approval of the proposed amendments to the Non-Qualified Stock Option Plan (Proposal No. 2 on the Proxy Card). PROPOSAL NO. 3 - RATIFICATION OF AUDITORS On October 20, 1998, the Audit Committee of the Board of Directors, pursuant to authority granted by the Board of Directors, approved the retention of KPMG Peat Marwick LLP ("KPMG"), independent certified public accountants, to audit the consolidated financial statements of the Company for the fiscal year ending June 30, 1999. KPMG served as auditor of the consolidated financial statements of the Company for the fiscal years ended June 30, 1998, June 30, 1997, and June 30, 1996. Representatives of KPMG are expected to be present at the Annual Meeting and will have the opportunity to make a statement should they desire to do so. Such representatives are also expected to be available to respond to questions. The Board of Directors recommends a vote FOR ratification of the selection of KPMG Peat Marwick LLP, independent certified public accountants, to audit the consolidated financial statements of the Company for the fiscal year ending June 30, 1999 (Proposal No. 3 on the Proxy Card). 16 ANNUAL REPORT TO STOCKHOLDERS The Company's Annual Report to Stockholders for the fiscal year ended June 30, 1998 accompanies this Proxy Statement. STOCKHOLDERS' PROPOSALS It is anticipated that the Company's fiscal 1999 Annual Meeting of Stockholders will be held on or about December 7, 1999. Stockholders who intend to present proposals at such Annual Meeting of Stockholders must submit their proposals to the Secretary of the Company on or before July 3, 1999. GENERAL The cost of soliciting proxies will be borne by the Company. In addition to mailing, proxies may be solicited by personal interview, telephone and telegraph, and by directors, officers and regular employees of the Company, without special compensation therefor. The Company expects to reimburse banks, brokers and other persons for their reasonable out-of-pocket expenses in handling proxy materials for beneficial owners of the Company's Common Stock. Unless contrary instructions are indicated on the proxy card, all Common Shares or Series A Preferred Shares represented by valid proxies received pursuant to this solicitation (and not revoked before they are voted) will be voted FOR the election of the nominees for directors named herein and FOR Proposal No. 2 and Proposal No. 3. Any proxy given pursuant to this solicitation may be revoked by the person giving it at any time before it is voted. Proxies may be revoked by filing with the Secretary of the Company written notice of revocation bearing a later date than the proxy, by duly executing a subsequent proxy relating to the same Common Shares or Series A Preferred Shares or by attending the Annual Meeting and voting in person. Attendance at the Annual Meeting will not in and of itself constitute revocation of a proxy unless the stockholder votes his or her Common Shares or Series A Preferred Shares in person at the Annual Meeting. Any notice revoking a proxy should be sent to the Secretary of the Company, John A. Caruso, at Enzon, Inc., 20 Kingsbridge Road, Piscataway, New Jersey 08854. The Board of Directors knows of no business other than that set forth above to be transacted at the meeting, but if other matters requiring a vote of the stockholders arise, the persons designated as proxies will vote the Common Shares or Series A Preferred Shares represented by the proxies in accordance with their judgment on such matters. If a stockholder specifies a different choice on the proxy, his or her Common Shares or Series A Preferred Shares will be voted in accordance with the specification so made. Please complete, sign and date the enclosed proxy card, which is revocable as described herein, and mail it promptly in the enclosed postage-paid envelope. IT IS IMPORTANT THAT PROXIES BE RETURNED PROMPTLY. WE URGE YOU TO FILL IN, SIGN AND RETURN THE ACCOMPANYING PROXY CARD, NO MATTER HOW LARGE OR SMALL YOUR HOLDINGS MAY BE. By order of the Board of Directors, John A. Caruso, Secretary Piscataway, New Jersey October 28, 1998 17 Proxy Card ENZON, INC. Annual Meeting of Stockholders December 1, 1998 This Proxy Is Solicited on Behalf of the Board of Directors Peter G. Tombros and John A. Caruso and each of them, as proxies, with full power of substitution in each of them, are hereby authorized to represent and to vote, as designated below and on the reverse side, on all proposals and in the discretion of the proxies on such other matters as may properly come before the annual meeting of stockholders of Enzon, Inc. (the "Company") to be held on December 1, 1998 or any adjournment(s), postponement(s), or other delay(s) thereof (the "Annual Meeting"), all shares of stock of the Company to which the undersigned is entitled to vote at the Annual Meeting. UNLESS OTHERWISE DIRECTED, THIS PROXY WILL BE VOTED "FOR" PROPOSALS 1, 2 and 3 AND WILL BE VOTED IN THE DISCRETION OF THE PROXIES ON SUCH OTHER MATTERS AS MAY PROPERLY COME BEFORE THE ANNUAL MEETING. THE BOARD OF DIRECTORS RECOMMENDS THAT STOCKHOLDERS VOTE "FOR" PROPOSALS 1, 2 and 3. (1) Election of the following nominees as Class III Directors to serve in such capacities until their successors are duly elected and qualified: ROLF A. CLASSON ROBERT LEBUHN (Authority to vote for any nominee(s) may be withheld by lining through the name(s) of any such nominee(s).) / / FOR all nominees / / WITHHOLD authority for all (2) Proposal to approve amendments to the Company's Non-Qualified Stock Option Plan, as set forth in the Company's Proxy Statement dated October 28, 1998. / / FOR / / AGAINST / / ABSTAIN (3) Ratification of the selection of KPMG Peat Marwick LLP to audit the consolidated financial statements of the Company for the fiscal year ending June 30, 1999. / / FOR / / AGAINST / / ABSTAIN / / Please check this box if you expect to attend the Annual Meeting in person. (Please sign exactly as name appears to the left, date and return. If shares are held by joint tenants, both should sign. When signing as attorney, executor, administrator, trustees or guardian, please give full title as such. If a corporation, please sign in full corporate name by president or other authorized officer. If a partnership, please sign in partnership name by authorized person.) Date: ------------------------------------------------------- ------------------------------------------------------- Sign Here ------------------------------------------------------- Signature (if held jointly) ------------------------------------------------------- Capacity (Title or Authority, i.e. Executor, Trustee) PLEASE SIGN, DATE AND MAIL YOUR PROXY TODAY.