THIS WARRANT AND THE SHARES OF COMMON STOCK ISSUED UPON ITS
                   EXERCISE ARE SUBJECT TO THE RESTRICTIONS ON
                 TRANSFER SET FORTH IN SECTION 4 OF THIS WARRANT


Warrant No. 5                                          Number of Shares: 150,000
                                                         (subject to adjustment)
Date of Issuance:  March 11, 1999


                                    IGI, INC.


                          Common Stock Purchase Warrant

                          (Void after October 1, 2004)


     IGI, Inc., a Delaware  corporation  (the  "Company"),  for value  received,
hereby  certifies that Fleet  Bank-N.H.,  a banking and trust company  organized
under the laws of New  Hampshire,  or its  registered  assigns (the  "Registered
Holder"),  is entitled,  subject to the terms set forth below,  to purchase from
the Company, at any time or from time to time on or after the 60th day after the
date of  issuance  and on or before  October 1, 2004 at not later than 5:00 p.m.
(Boston, Massachusetts time), 150,000 shares of Common Stock, $.01 par value per
share (the "Common  Stock"),  of the Company,  at a Exercise  Price of $2.00 per
share. The shares issuable upon exercise of this Warrant, and the Exercise Price
per share, each as adjusted from time to time pursuant to the provisions of this
Warrant,  are hereinafter  referred to as the "Warrant Shares" and the "Exercise
Price," respectively.

     1. Certain Definitions.  As used in this Warrant, the following terms shall
have the following respective meanings:

     "Commission"  means the  Securities and Exchange  Commission,  or any other
Federal agency at the time administering the Securities Act.

     "Registration  Statement"  means  a  registration  statement  filed  by the
Company  with the  Commission  for a public  offering  and sale of Common  Stock
(other  than a  registration  statement  on  Form  S-8 or  Form  S-4,  or  their
successors, or any other form for a similar limited purpose, or any registration
statement  covering  only  securities  proposed  to be  issued in  exchange  for
securities or assets of another corporation).


                                       -1-



     "Registrable  Shares"  means  (i) the  Warrant  Shares,  and (ii) any other
shares of Common  Stock  issued in  respect  of such  shares  (because  of stock
splits,  stock  dividends,  reclassifications,   recapitalizations,  or  similar
events);  provided,  however,  that shares of Common Stock which are Registrable
Shares  shall  cease to be  Registrable  Shares (i) upon any sale  pursuant to a
Registration  Statement  or Rule 144 under the  Securities  Act or (ii) upon any
sale in any manner to a person or entity which,  by virtue of Section 13 of this
Warrant, is not entitled to the rights provided by this Warrant.

     "Securities Act" means the Security Act of 1933, as amended, or any similar
Federal  statute,  and the rules and regulations of the Commission  issued under
such Act, as they each may, from time to time, be in effect.

     2. Exercise.

     (a) This Warrant may be exercised by the Registered  Holder, in whole or in
part, by  surrendering  this Warrant,  with the purchase form appended hereto as
Exhibit I duly executed by such Registered Holder or by such Registered Holder's
duly authorized  attorney,  at the principal  office of the Company,  or at such
other office or agency as the Company may  designate,  accompanied by payment in
full,  in lawful money of the United  States,  of the Exercise  Price payable in
respect of the number of Warrant Shares issued upon such exercise.

     (b) The Registered  Holder may, at its option,  elect to pay some or all of
the Exercise  Price  payable  upon an exercise of this  Warrant by  cancelling a
portion of this  Warrant  exercisable  for such  number of Warrant  Shares as is
determined  by dividing (i) the total  Exercise  Price payable in respect of the
number of Warrant  Shares being issued upon such  exercise by (ii) the excess of
the Fair  Market  Value per share of Common  Stock as of the  effective  date of
exercise,  as determined pursuant to subsection 2(c) below (the "Exercise Date")
over the Exercise Price per share.  If the Registered  Holder wishes to exercise
this  Warrant  pursuant  to this method of payment  with  respect to the maximum
number of Warrant Shares  issuable  pursuant to this method,  then the number of
Warrant Shares so issuable shall be equal to the total number of Warrant Shares,
minus the product obtained by multiplying (x) the total number of Warrant Shares
by (y) a fraction,  the numerator of which shall be the Exercise Price per share
and the  denominator of which shall be the Fair Market Value per share of Common
Stock as of the Exercise  Date.  The Fair Market Value per share of Common Stock
shall be determined as follows:

               (i) If the  Common  Stock  is  listed  on a  national  securities
          exchange,  the Nasdaq  Stock Market or another  nationally  recognized
          exchange or trading  system as of the Exercise  Date,  the Fair Market
          Value per share of Common  Stock  shall be deemed to be the average of
          the last reported sale price per share of


                                       -2-



Common  Stock  thereon for the ten  consecutive  trading  days ending on the day
immediately prior to the Exercise Date;

               (ii) If the Common  Stock is not listed on a national  securities
          exchange,  the Nasdaq  Stock Market or another  nationally  recognized
          exchange or trading  system as of the Exercise  Date,  the Fair Market
          Value per share of Common  Stock shall be deemed to be the amount most
          recently  determined  in good  faith  by the  Board  of  Directors  to
          represent  the  fair  market  value  per  share  of the  Common  Stock
          (including without limitation a determination for purposes of granting
          Common Stock options or issuing Common Stock under an employee benefit
          plan of the Company);  and, upon request of the Registered Holder, the
          Board of Directors (or a representative thereof) shall promptly notify
          the  Registered  Holder of the Fair  Market  Value per share of Common
          Stock.  Notwithstanding  the foregoing,  if the Board of Directors has
          not made such a determination  within a forty-five day period prior to
          the Exercise Date,  then (A) the Fair Market Value per share of Common
          Stock shall be the amount next  determined  in good faith by the Board
          of  Directors  to  represent  the fair  market  value per share of the
          Common  Stock  (including   without  limitation  a  determination  for
          purposes of granting  Common  Stock  options or issuing  Common  Stock
          under an  employee  benefit  plan of the  Company),  (B) the  Board of
          Directors shall make such a determination  within 15 days of a request
          by the  Registered  Holder that it do so, and (C) the exercise of this
          Warrant  pursuant to this  subsection 2(b) shall be delayed until such
          determination is made.

     (c) Each  exercise of this  Warrant  shall be deemed to have been  effected
immediately  prior to the close of  business  on the day on which  this  Warrant
shall have been surrendered to the Company as provided in subsection 2(a) above.
At such time, the person or persons in whose name or names any  certificates for
Warrant  Shares shall be issuable  upon such  exercise as provided in subsection
2(d) below shall be deemed to have become the holder or holders of record of the
Warrant Shares represented by such certificates.

     (d) As soon as practicable after the exercise of this Warrant in full or in
part, and in any event within 10 days thereafter,  the Company,  at its expense,
will cause to be issued in the name of, and delivered to, the Registered Holder,
or as such  Registered  Holder  (upon  payment by such Holder of any  applicable
transfer taxes) may direct:

               (i) a certificate or certificates  for the number of full Warrant
          Shares to which such  Registered  Holder  shall be entitled  upon such
          exercise  plus,  in  lieu  of  any  fractional  share  to  which  such
          Registered  Holder  would  otherwise  be  entitled,  cash in an amount
          determined pursuant to Section 4 hereof; and

               (ii) in case such  exercise  is in part  only,  a new  warrant or
          warrants  (dated  the  date  hereof)  of like  tenor,  calling  in the
          aggregate on the face or


                                       -3-



faces thereof for the number of Warrant Shares equal  (without  giving effect to
any  adjustment  therein) to the number of such shares called for on the face of
this  Warrant  minus the sum of (a) the number of such shares  purchased  by the
Registered  Holder upon such exercise plus (b) the number of Warrant  Shares (if
any) covered by the portion of this Warrant cancelled in payment of the Exercise
Price payable upon such exercise pursuant to subsection 2(b) above.

     (e)  Notwithstanding  the foregoing,  the Warrant shall become  immediately
exercisable  by the  Registered  Holder upon (i) the  occurrence  of an Event of
Default (as defined in the Second  Extension  Agreement  dated March 11, 1999 by
and among the Registered Holder, Fleet Bank-N.H., the Company and certain of its
subsidiaries  (the "Second  Extension  Agreement"))  or (ii) the mailing date of
written  notice by the  Company of its  intention  to  exercise  its right under
Section 8 to redeem Available Warrant Shares (as defined under subsection 8(a)).

     3. Adjustments.

     (a) General. The Exercise Price shall be subject to adjustment from time to
time pursuant to the terms of this Section 3.

     (b) Diluting Issuances.

               (i) Special  Definitions.  For purposes of this subsection  3(b),
          the following definitions shall apply:

                    (A)  "Option"  shall mean  rights,  options or  warrants  to
               subscribe  for,  purchase or  otherwise  acquire  Common Stock or
               Convertible  Securities,  excluding  options  described in clause
               (II) of subsection 3(b)(i)(D) below.

                    (B) "Original  Issue Date" shall mean the date on which this
               Warrant was first issued.

                    (C)  "Convertible  Securities"  shall mean any  evidences of
               indebtedness,  shares or other securities  directly or indirectly
               convertible into or exchangeable for Common Stock.

                    (D)  "Additional  Shares of  Common  Stock"  shall  mean all
               shares  of  Common  Stock  issued  (or,  pursuant  to  subsection
               3(b)(iii)  below,  deemed to be issued) by the Company  after the
               Original Issue Date,  other than shares of Common Stock issued or
               issuable:

               (I)  by reason of a  dividend,  stock  split,  split-up  or other
                    distribution on shares of Common Stock that are


                                       -4-



                    excluded from the definition of Additional  Shares of Common
                    Stock by this clause (I); or

               (II) to employees or directors of, or consultants to, the Company
                    pursuant to a plan  adopted by the Board of Directors of the
                    Company.

               (ii) No  Adjustment  of Exercise  Price.  No  adjustments  to the
          Exercise  Price  shall be made  unless  the  consideration  per  share
          (determined pursuant to subsection 3(b)(v)) for an Additional Share of
          Common Stock issued or deemed to be issued by the Company is less than
          the Exercise Price in effect on the date of, and immediately prior to,
          the issue of such Additional Shares.

               (iii) Issue of Securities  Deemed Issue of  Additional  Shares of
          Common  Stock.  If the  Company at any time or from time to time after
          the  Original  Issue  Date  shall  issue any  Options  or  Convertible
          Securities or shall fix a record date for the determination of holders
          of any class of  securities  entitled to receive  any such  Options or
          Convertible  Securities,  then the maximum  number of shares of Common
          Stock (as set forth in the instrument  relating thereto without regard
          to any provision contained therein for a subsequent adjustment of such
          number)  issuable upon the exercise of such Options or, in the case of
          Convertible   Securities  and  Options  therefor,  the  conversion  or
          exchange  of  such  Convertible  Securities,  shall  be  deemed  to be
          Additional  Shares of Common Stock issued as of the time of such issue
          or, in case such a record date shall have been fixed,  as of the close
          of business on such record date,  provided that  Additional  Shares of
          Common  Stock  shall  not be deemed to have  been  issued  unless  the
          consideration  per share  (determined  pursuant to subsection  3(b)(v)
          hereof) of such  Additional  Shares of Common Stock would be less than
          the Exercise Price in effect on the date of and  immediately  prior to
          such issue,  or such  record  date,  as the case may be, and  provided
          further  that in any such  case in which  Additional  Shares of Common
          Stock are deemed to be issued:

                    (A) No further  adjustment  in the  Exercise  Price shall be
               made  upon the  subsequent  issue of  Convertible  Securities  or
               shares of Common  Stock  upon the  exercise  of such  Options  or
               conversion or exchange of such Convertible Securities;

                    (B) If such Options or Convertible Securities by their terms
               provide, with the passage of time or otherwise,  for any increase
               in the consideration  payable to the Company,  upon the exercise,
               conversion or exchange thereof,  the Exercise Price computed upon
               the original  issue  thereof (or upon the  occurrence of a record
               date with respect thereto),  and any subsequent adjustments based
               thereon,  shall,  upon any such increase becoming  effective,  be
               recomputed  to reflect such  increase  insofar as it affects such
               Options  or the  rights of  conversion  or  exchange  under  such
               Convertible Securities;


                                       -5-



                    (C) Upon the expiration or  termination  of any  unexercised
               Option,  the  Exercise  Price  shall not be  readjusted,  but the
               Additional  Shares of Common Stock deemed issued as the result of
               the original  issue of such Option shall not be deemed issued for
               the purposes of any subsequent adjustment of the Exercise Price;

                    (D) In the event of any  change  in the  number of shares of
               Common Stock  issuable upon the exercise,  conversion or exchange
               of any Option or Convertible Security, including, but not limited
               to, a change resulting from the anti-dilution provisions thereof,
               the Exercise  Price then in effect shall  forthwith be readjusted
               to such Exercise  Price as would have obtained had the adjustment
               which was made upon the  issuance of such  Option or  Convertible
               Security not  exercised  or  converted  prior to such change been
               made upon the basis of such change; and

                    (E) No  readjustment  pursuant  to  Clause  (B) or (D) above
               shall  have the effect of  increasing  the  Exercise  Price to an
               amount which  exceeds the lower of (i) the Exercise  Price on the
               original  adjustment  date, or (ii) the Exercise Price that would
               have resulted  from any issuances of Additional  Shares of Common
               Stock between the original  adjustment date and such readjustment
               date.

          (iv)  Adjustment of Exercise Price Upon Issuance of Additional  Shares
     of  Common  Stock.  In the event the  Company  shall at any time  after the
     Original  Issue Date issue  Additional  Shares of Common  Stock  (including
     Additional  Shares  of  Common  Stock  deemed  to  be  issued  pursuant  to
     subsection  3(b)(iii),  but  excluding  shares  issued  as  a  dividend  or
     distribution or upon a stock split or combination as provided in subsection
     3(c)), without consideration or for a consideration per share less than the
     Exercise  Price  in  effect  on the date of and  immediately  prior to such
     issue,  then and in such  event,  such  Exercise  Price  shall be  reduced,
     concurrently  with such issue, to a price  (calculated to the nearest cent)
     determined  by  multiplying  such  Exercise  Price by a  fraction,  (A) the
     numerator  of which  shall be (1) the  number of  shares  of  Common  Stock
     outstanding  immediately  prior to such issue plus (2) the number of shares
     of  Common  Stock  which  the  aggregate  consideration  received  or to be
     received by the Company for the total number of Additional Shares of Common
     Stock  so  issued  would  purchase  at  such  Exercise  Price;  and (B) the
     denominator  of  which  shall be the  number  of  shares  of  Common  Stock
     outstanding  immediately  prior  to such  issue  plus  the  number  of such
     Additional  Shares of Common Stock so issued;  provided  that,  (i) for the
     purpose of this  subsection  3(b)(iv),  all shares of Common Stock issuable
     upon  exercise  or  conversion   of  Options  or   Convertible   Securities
     outstanding  immediately  prior  to  such  issue  shall  be  deemed  to  be
     outstanding  (other than shares excluded from the definition of "Additional
     Shares of Common Stock" by virtue of clause (II) of subsection 3(b)(i)(D)),
     and (ii) the  number  of  shares  of  Common  Stock  deemed  issuable  upon
     conversion of such outstanding Options and Convertible Securities shall not
     give effect to any  adjustments to the conversion  price or conversion rate
     of


                                      -6-



such Options or Convertible Securities resulting from the issuance of Additional
Shares of Common Stock that is the subject of this calculation.

     Notwithstanding  the foregoing,  the applicable Exercise Price shall not be
so reduced at such time if the amount of such reduction  would be an amount less
than $.05,  but any such  amount  shall be carried  forward and  reduction  with
respect  thereto made at the time of and together with any subsequent  reduction
which,  together  with such  amount  and any other  amount or amounts so carried
forward, shall aggregate $.05 or more.

               (v)  Determination  of   Consideration.   For  purposes  of  this
          subsection  3(b),  the  consideration  received by the Company for the
          issue of any  Additional  Shares of Common  Stock shall be computed as
          follows:

                    (A) Cash and Property: Such consideration shall:

                         (I) insofar as it consists of cash,  be computed at the
                    aggregate of cash received by the Company, excluding amounts
                    paid or payable for accrued interest or accrued dividends;

                         (II)  insofar as it  consists  of  property  other than
                    cash,  be computed at the fair market  value  thereof at the
                    time of such issue, as determined in good faith by the Board
                    of Directors; and

                         (III) in the event  Additional  Shares of Common  Stock
                    are issued together with other shares or securities or other
                    assets of the Company for  consideration  which covers both,
                    be  the  proportion  of  such   consideration  so  received,
                    computed  as  provided  in clauses  (I) and (II)  above,  as
                    determined in good faith by the Board of Directors.

                    (B) Options and Convertible  Securities.  The  consideration
               per share received by the Company for Additional Shares of Common
               Stock  deemed  to  have  been  issued   pursuant  to   subsection
               3(b)(iii),  relating to Options and Convertible Securities, shall
               be determined by dividing

                         (x) the total amount, if any, received or receivable by
                    the Company as  consideration  for the issue of such Options
                    or Convertible Securities, plus the minimum aggregate amount
                    of additional consideration (as set forth in the instruments
                    relating thereto,  without regard to any provision contained
                    therein for a subsequent  adjustment of such  consideration)
                    payable to the Company  upon the exercise of such Options or
                    the conversion or exchange of such  Convertible  Securities,
                    or in the case of Options for  Convertible  Securities,  the
                    exercise of such Options for Convertible  Securities and the
                    conversion or exchange of such Convertible Securities, by


                                       -7-



                         (y) the  maximum  number of shares of Common  Stock (as
                    set  forth  in the  instruments  relating  thereto,  without
                    regard to any provision  contained  therein for a subsequent
                    adjustment  of such  number)  issuable  upon the exercise of
                    such  Options  or  the   conversion   or  exchange  of  such
                    Convertible Securities.

     (c)  Recapitalizations.  If  outstanding  shares of Common  Stock  shall be
subdivided  into a greater  number of shares or a dividend in Common Stock shall
be paid in respect of Common  Stock,  the Exercise  Price in effect  immediately
prior  to  such  subdivision  or at the  record  date  of  such  dividend  shall
simultaneously  with the  effectiveness of such subdivision or immediately after
the record date of such  dividend be  proportionately  reduced.  If  outstanding
shares of Common Stock shall be combined  into a smaller  number of shares,  the
Exercise  Price  in  effect   immediately  prior  to  such  combination   shall,
simultaneously  with the effectiveness of such combination,  be  proportionately
increased.

     (d)  Mergers,  etc.  If there shall  occur any  capital  reorganization  or
reclassification  of the  Common  Stock  (other  than a change in par value or a
subdivision  or combination  as provided for in subsection  3(c) above),  or any
consolidation  or merger of the Company with or into another  corporation,  or a
transfer of all or substantially all of the assets of the Company, then, as part
of any such reorganization, reclassification,  consolidation, merger or sale, as
the case may be, lawful provision shall be made so that the Registered Holder of
this Warrant shall have the right thereafter to receive upon the exercise hereof
the kind and amount of shares of stock or other  securities  or  property  which
such Registered Holder would have been entitled to receive if, immediately prior
to any such reorganization, reclassification,  consolidation, merger or sale, as
the case may be, such Registered  Holder had held the number of shares of Common
Stock which were then issuable  upon the exercise of this  Warrant.  In any such
case,  appropriate  adjustment  (as  reasonably  determined in good faith by the
Board of  Directors  of the  Company)  shall be made in the  application  of the
provisions set forth herein with respect to the rights and interests  thereafter
of the Registered Holder of this Warrant,  such that the provisions set forth in
this Section 3 (including  provisions with respect to adjustment of the Exercise
Price) shall thereafter be applicable,  as nearly as is reasonably  practicable,
in relation to any shares of stock or other  securities  or property  thereafter
deliverable upon the exercise of this Warrant.

     (e) Adjustment in Number of Warrant Shares. When any adjustment is required
to be made in the Exercise Price, the number of Warrant Shares  purchasable upon
the  exercise  of this  Warrant  shall be changed to the  number  determined  by
dividing (i) an amount equal to the number of shares  issuable upon the exercise
of this Warrant immediately prior to such adjustment, multiplied by the Exercise
Price in effect immediately prior to such adjustment, by (ii) the Exercise Price
in effect immediately after such adjustment.


                                       -8-



     (f)  Certificate of Adjustment.  When any adjustment is required to be made
pursuant to this Section 3, the Company shall  promptly  mail to the  Registered
Holder a certificate  setting forth the Exercise Price after such adjustment and
setting forth a brief  statement of the facts  requiring such  adjustment.  Such
certificate  shall  also  set  forth  the  kind  and  amount  of  stock or other
securities or property into which this Warrant  shall be  exercisable  following
such adjustment.

     4. Fractional  Shares.  The Company shall not be required upon the exercise
of this Warrant to issue any  fractional  shares,  but shall make an  adjustment
therefor  in cash on the  basis of the Fair  Market  Value  per  share of Common
Stock, as determined pursuant to subsection 2(b) above.

     5. Requirements for Transfer.

     (a) This Warrant and the Warrant  Shares  shall not be sold or  transferred
unless either (i) they first shall have been registered under the Securities Act
of 1933, as amended (the "Securities Act"), or (ii) the Company first shall have
been furnished with an opinion of legal counsel,  reasonably satisfactory to the
Company,  to  the  effect  that  such  sale  or  transfer  is  exempt  from  the
registration requirements of the Act.

     (b)  Notwithstanding  the foregoing,  no registration or opinion of counsel
shall  be  required  for  (i) a  transfer  by a  Registered  Holder  which  is a
partnership  to a  partner  of such  partnership  or a retired  partner  of such
partnership  who  retires  after the date  hereof,  or to the estate of any such
partner or retired partner, if the transferee agrees in writing to be subject to
the terms of this Section 5, (ii) a transfer  made in  accordance  with Rule 144
under the Act, or (iii) a transfer by a Registered Holder which is a corporation
to an  affiliate,  as  defined  under  Rule 144 of the  Securities  Act,  if the
transferee agrees in writing to be subject to the terms of this Section.

     (c)  Each  certificate  representing  Warrant  Shares  shall  bear a legend
substantially in the following form:

          "The  securities   represented  by  this  certificate  have  not  been
          registered  under the Securities Act of 1933, as amended,  and may not
          be offered,  sold or otherwise  transferred,  pledged or  hypothecated
          unless and until such  securities are registered  under such Act or an
          opinion of counsel  satisfactory  to the  Company is  obtained  to the
          effect that such registration is not required."


                                       -9-



The foregoing  legend shall be removed from the  certificates  representing  any
Warrant  Shares,  at the  request  of the holder  thereof,  at such time as they
become eligible for resale pursuant to Rule 144(k) under the Act.

     6. No  Impairment.  The Company  will not, by  amendment  of its charter or
through reorganization,  consolidation,  merger, dissolution,  sale of assets or
any other voluntary action, avoid or seek to avoid the observance or performance
of any of the terms of this Warrant,  but will at all times in good faith assist
in the  carrying  out of all such terms and in the taking of all such  action as
may be necessary or  appropriate in order to protect the rights of the holder of
this Warrant against impairment.

     7.  Liquidating  Dividends.  If the  Company  pays a  dividend  or  makes a
distribution on the Common Stock payable  otherwise than in cash out of earnings
or earned surplus  (determined in accordance with generally accepted  accounting
principles)  except for a stock  dividend  payable in shares of Common  Stock (a
"Liquidating  Dividend"),  then  the  Company  will  pay  or  distribute  to the
Registered Holder of this Warrant,  upon the exercise hereof, in addition to the
Warrant Shares issued upon such exercise,  the Liquidating  Dividend which would
have been paid to such  Registered  Holder if he had been the owner of record of
such Warrant Shares immediately prior to the date on which a record is taken for
such  Liquidating  Dividend or, if no record is taken,  the date as of which the
record holders of Common Stock entitled to such dividends or distribution are to
be determined.

     8. Optional Redemption.

     (a) At any time,  the Company may, at its option,  redeem all, but not less
than  all,  of the  Warrant  Shares  for  which the  Registered  Holder  has not
exercised its right to be issued (the  "Available  Warrant  Shares"),  by paying
$3.33 per Available  Warrant Share (subject to appropriate  adjustment for stock
splits,  stock  dividends,   combinations  or  other  similar  recapitalizations
affecting  such shares) in cash for each  Available  Warrant Share then redeemed
(hereinafter referred to as the "Redemption Price"); provided, however, that the
Registered  Holder may  immediately  exercise its Warrant or Warrants until such
time on or 15 days prior to the Redemption Date (as defined below).

     (b) At  least  15 days  prior  to the  date  fixed  for any  redemption  of
Available  Warrant Shares  (hereinafter  referred to as the "Redemption  Date"),
written  notice  shall be mailed,  by first class or  registered  mail,  postage
prepaid, to the Registered Holder,  notifying such holder of the election of the
Company to redeem such Available Warrant Shares,  specifying the Redemption Date
and calling upon the  Registered  Holder to  surrender  to the  Company,  in the
manner and at the place  designated,  its Warrant or Warrants,  representing the
Available Warrant Shares to be redeemed (such notice is hereinafter  referred to
as the "Redemption  Notice"). On or prior to the Redemption Date (subject to the
Registered Holder's right to exercise


                                      -10-




such  Warrants  prior to the  Redemption  Date),  the  Registered  Holder  shall
surrender its Warrant or Warrants  representing  Available Warrant Shares to the
Company, in the manner and at the place designated in the Redemption Notice, and
thereupon the  Redemption  Price of such shares shall be payable to the order of
the Registered Holder and each surrendered Warrant shall be cancelled.  From and
after the Redemption Date,  unless there shall have been a default in payment of
the Redemption Price (or the Registered  Holder has exercised the Warrants prior
to such Redemption  Date),  all rights of the Registered  Holder  designated for
redemption in the Redemption  Notice as the Registered  Holder (except the right
to receive the Redemption  Price without interest upon surrender of the Warrant)
shall cease with respect to the Warrant or Warrants  representing  the Available
Warrant Shares, and such Warrant or Warrants shall not thereafter be transferred
on the  books of the  Company  or be deemed to be  outstanding  for any  purpose
whatsoever.

     9. Notices of Record Date, etc. In case:

     (a) the Company  shall take a record of the holders of its Common Stock (or
other stock or  securities  at the time  deliverable  upon the  exercise of this
Warrant) for the purpose of  entitling or enabling  them to receive any dividend
or other distribution,  or to receive any right to subscribe for or purchase any
shares of stock of any class or any other  securities,  or to receive  any other
right; or

     (b) of any capital  reorganization of the Company,  any reclassification of
the capital  stock of the Company,  any  consolidation  or merger of the Company
with or into another  corporation (other than a consolidation or merger in which
the Company is the surviving  entity),  or any transfer of all or  substantially
all of the assets of the Company; or

     (c) of the voluntary or involuntary dissolution,  liquidation or winding-up
of the Company,  then,  and in each such case, the Company will mail or cause to
be mailed to the Registered Holder of this Warrant a notice  specifying,  as the
case may be,  (i) the date on which a record is to be taken for the  purpose  of
such dividend,  distribution  or right,  and stating the amount and character of
such dividend,  distribution  or right, or (ii) the effective date on which such
reorganization, reclassification,  consolidation, merger, transfer, dissolution,
liquidation or winding-up is to take place, and the time, if any is to be fixed,
as of which  the  holders  of record of  Common  Stock (or such  other  stock or
securities at the time  deliverable  upon the exercise of this Warrant) shall be
entitled  to  exchange  their  shares of Common  Stock (or such  other  stock or
securities)   for   securities   or  other   property   deliverable   upon  such
reorganization, reclassification,  consolidation, merger, transfer, dissolution,
liquidation  or  winding-up.  Such notice shall be mailed at least ten (10) days
prior to the  record  date or  effective  date for the event  specified  in such
notice.


                                      -11-



     10.  Reservation  of Stock.  The Company will at all times reserve and keep
available,  solely for issuance and delivery  upon the exercise of this Warrant,
such number of Warrant Shares and other stock,  securities and property, as from
time to time shall be issuable upon the exercise of this Warrant.

     11.  Exchange of Warrants.  Upon the surrender by the Registered  Holder of
any Warrant or  Warrants,  properly  endorsed,  to the Company at the  principal
office of the Company,  the Company will, subject to the provisions of Section 5
hereof, issue and deliver to or upon the order of such Registered Holder, at the
Company's  expense, a new Warrant or Warrants of like tenor, in the name of such
Registered  Holder or as such Registered Holder (upon payment by such Registered
Holder of any applicable transfer taxes) may direct, calling in the aggregate on
the face or faces thereof for the number of shares of Common Stock called for on
the face or faces of the Warrant or Warrants so surrendered.

     12.   Replacement  of  Warrants.   Upon  receipt  of  evidence   reasonably
satisfactory  to the Company of the loss,  theft,  destruction  or mutilation of
this Warrant and (in the case of loss, theft or destruction) upon delivery of an
indemnity agreement (with surety if reasonably required) in an amount reasonably
satisfactory to the Company,  or (in the case of mutilation)  upon surrender and
cancellation  of this Warrant,  the Company will issue,  in lieu thereof,  a new
Warrant of like tenor.

     13. Transfers, etc.

     (a) The Company will maintain a register containing the name and address of
the Registered  Holder of this Warrant.  Any Registered Holder may change its or
his  address as shown on the warrant  register by written  notice to the Company
requesting such change.

     (b) Subject to the  provisions  of Section 5 hereof,  this  Warrant and all
rights hereunder are  transferable,  in whole or in part, upon surrender of this
Warrant with a properly  executed  assignment (in the form of Exhibit II hereto)
at the principal office of the Company.

     (c) Until any transfer of this Warrant is made in the warrant register, the
Company may treat the  Registered  Holder of this Warrant as the absolute  owner
hereof for all  purposes;  provided,  however,  that if and when this Warrant is
properly  assigned in blank,  the Company  may (but shall not be  obligated  to)
treat  the  bearer  hereof  as the  absolute  owner  hereof  for  all  purposes,
notwithstanding any notice to the contrary.


                                      -12-



     14. Mailing of Notices,  etc. All notices and other communications from the
Company to the Registered  Holder of this Warrant shall be mailed by first-class
certified or registered mail,  postage prepaid,  to the address furnished to the
Company in writing by the last Registered  Holder of this Warrant who shall have
furnished  an  address  to  the  Company  in  writing.  All  notices  and  other
communications  from the  Registered  Holder of this  Warrant  or in  connection
herewith to the Company shall be mailed by  first-class  certified or registered
mail,  postage prepaid,  to the Company at its principal office set forth below.
If the Company should at any time change the location of its principal office to
a place other than as set forth below,  it shall give prompt  written  notice to
the  Registered  Holder of this Warrant and  thereafter  all  references in this
Warrant to the location of its principal  office at the particular time shall be
as so specified in such notice.

     15. No Rights as  Stockholder.  Until the  exercise  of this  Warrant,  the
Registered  Holder of this  Warrant  shall not have or  exercise  any  rights by
virtue hereof as a stockholder of the Company.

     16.  Change or Waiver.  Any term of this  Warrant  may be changed or waived
only by an instrument in writing  signed by the party against which  enforcement
of the change or waiver is sought.

     17.  Headings.  The  headings in this Warrant are for purposes of reference
only and shall not limit or  otherwise  affect the meaning of any  provision  of
this Warrant.

     18.  Governing  Law.  This  Warrant  will be governed by and  construed  in
accordance with the laws of Delaware.

     19. Registration Rights.

     (a) The Registered  Holder shall have the registration  rights with respect
to the  Warrant  Shares  as  specified  in  Section  9 of the  Second  Extension
Agreement.

     (b)  Furthermore,  the  Registered  Holder shall be entitled to "piggyback"
registration  rights  for so long as the  Registered  Holder  shall own  Warrant
Shares.  Whenever the Company  proposes to file a Registration  Statement (other
than  pursuant to  subsection  19(a) at any time and from time to time, it will,
prior to such  filing,  give  written  notice  to the  Registered  Holder of its
intention to do so and, upon the written request of the Registered  Holder given
within 20 days after the Company provides such notice (which request shall state
the intended  method of disposition  of such  Registrable  Shares),  the Company
shall use its best efforts to cause all Registrable Shares which the Company has
been requested by such Registered  Holder to register to be registered under the
Securities Act to the extent necessary to


                                      -13-



permit their sale or other  disposition in accordance with the intended  methods
of distribution specified in the request of the Registered Holder; provided that
the  Company  shall have the right to  postpone  or  withdraw  any  registration
effected pursuant to this subsection 19(b) without  obligation to the Registered
Holder or any  persons or entities  to which the rights  under this  Warrant are
transferred by the  Registered  Holder,  its  successors or assigns  pursuant to
Section 13 hereof.

     (c) In connection with any registration under subsection 19(b) involving an
underwriting,  the Company  shall not be  required  to include  any  Registrable
Shares in such  registration  unless the holders thereof accept the terms of the
underwriting as agreed upon between the Company and the underwriters selected by
it (provided that such terms must be consistent  with this  Warrant).  If in the
opinion of the  managing  underwriter  it is  appropriate  because of  marketing
factors  to limit  the  number  of  Registrable  Shares  to be  included  in the
offering, then the Company shall be required to include in the registration only
that  number of  Registrable  Shares,  if any,  which the  managing  underwriter
believes should be included therein.  If the number of Registrable  Shares to be
included in the offering in accordance with the foregoing is less than the total
number of shares which the holders of  Registrable  Shares have  requested to be
included, then the holders of Registrable Shares who have requested registration
and other  holders of securities  entitled to include them in such  registration
shall  participate in the registration pro rata based upon their total ownership
of shares of Common Stock (giving effect to the conversion  into Common Stock of
all securities convertible  thereinto).  If any holder would thus be entitled to
include more securities than such holder requested to be registered,  the excess
shall be  allocated  among  other  requesting  holders  pro  rata in the  manner
described in the preceding sentence.

     20. Registration Procedures. If and whenever the Company is required by the
provisions  of this  Warrant  to use to effect  the  registration  of any of the
Registrable Shares under the Securities Act, the Company shall:

          (a)  furnish to the  Registered  Holder  such  number of copies as the
     Registered Holder shall reasonably  request of the prospectus,  including a
     preliminary  prospectus  and any  amendments  or  supplements  thereto,  in
     conformity with the requirements of the Securities Act;

          (b) use its best efforts to register or qualify the Registrable Shares
     covered by the  Registration  Statement  under the securities  laws of such
     states  as  the  Registered  Holder  shall  reasonably  request;  provided,
     however,  that the Company  shall not be required in  connection  with this
     subsection  20(b) to qualify as a foreign  corporation or execute a general
     consent to service of process in any jurisdiction;

          (c)  promptly  notify  the  Registered  Holder,  if  the  Company  has
     delivered  preliminary or final  prospectuses to the Registered  Holder and
     after having


                                      -14-



     done so, the prospectus is amended to comply with the  requirements  of the
     Securities  Act and, if  requested by the Company,  the  Registered  Holder
     shall immediately cease making offers or sales of Registrable  Shares under
     the Registration  Statement and return all prospectuses to the Company. The
     Company  shall  promptly   provide  the  Registered   Holder  with  revised
     prospectuses  and,  following  receipt  of the  revised  prospectuses,  the
     Registered  Holder shall be free to resume  making  offers and sales of the
     Registrable Shares; and

          (d) pay the expenses  incurred by it in complying with its obligations
     under this Warrant in connection with  registration  rights,  including all
     registration  and filing  fees,  exchange  listing  fees,  expenses for the
     preparation of the  Registration  statement,  prospectus and any amendments
     and supplements thereto, printing and photocopy expenses, fees and expenses
     of counsel for the Company,  and fees and expenses of  accountants  for the
     Company, but excluding:  (i) selling commissions or underwriting  discounts
     incurred by the Registered  Holder in connection  with sales of Registrable
     Shares under the  Registration  Statement and (ii) the fees and expenses of
     any counsel retained by the Registered Holder.

     21. Requirements of Registered Holder. The Company shall not be required to
effect the  registration of any of the  Registrable  Shares under the Securities
Act pursuant to this Warrant unless:

          (a) the Registered  Holder owning such shares furnishes to the Company
     in  writing  such  information  regarding  such  Registered  Holder and the
     proposed  sale of  Registrable  Shares  by such  Registered  Holder  as the
     Company may reasonably  request in writing in connection with the filing of
     a Registration Statement or as shall be required in connection therewith by
     the Commission or any state securities law authorities; and

          (b) Such  Registered  Holder  shall have  provided  to the Company its
     written  agreement  that in the  event  of any  registration  of any of the
     Registrable Shares under the Securities Act pursuant to this Warrant,  each
     Registered Holder will indemnify the Company and its officers and directors
     and each person,  if any,  who controls any thereof  (within the meaning of
     the  Securities  Act)  against  any and all  claims,  losses,  damages  and
     liabilities (or actions in respect  thereof) arising out of or based on any
     untrue  statement  (or  alleged  untrue  statement)  of any  material  fact
     contained in any prospectus or other document incident to any registration,
     qualification  or  compliance  (or in any related  Registration  Statement,
     notification  or the like) or any omission  (or alleged  omission) to state
     therein any  material  fact  required to be stated  therein or necessary to
     make the statement therein not misleading,  and such Registered Holder will
     reimburse  the Company and each other person  indemnified  pursuant to this
     Section  21 for any legal and any other  expenses  reasonably  incurred  in
     connection with  investigating or defending any such claim,  loss,  damage,
     liability or action; provided, however, that this Section 21 shall apply


                                      -15-



     only if (and only to the extent  that) such  statement or omission was made
     in  reliance  upon  written  information  furnished  to the  Company  in an
     instrument  duly  executed  by such  Registered  Holder  and  stated  to be
     specifically  for use in such  prospectus  or other  document  (or  related
     Registration  Statement,  notification  or the  like) or any  amendment  or
     supplement  thereto;  and,  provided further that each Registered  Holder's
     liability  hereunder with respect to any particular  registration  shall be
     limited to an amount equal to the net proceeds  received by such Registered
     Holder from the Registrable  Securities  sold by such Registered  Holder in
     such registration.

     22.  Indemnification by Company. In the event of any registration of any of
the  Registrable  Shares under the Securities Act pursuant to this Warrant,  the
Company will indemnify each  Registered  Holder and each person who controls the
Registered Holder (within the meaning of the Securities Act) against any and all
claims,  losses, damages and liabilities (or actions in respect thereof) arising
out of or based on any untrue  statement  (or alleged  untrue  statement) of any
material  fact  contained in any  prospectus or other  document  incident to any
registration,  qualification  or  compliance  (or  in any  related  Registration
Statement,  notification  or the like) or any omission (or alleged  omission) to
state therein any material  fact  required to be stated  therein or necessary to
make the statements  therein not misleading,  or any violation by the Company of
any rule or regulation  promulgated  under the  Securities Act applicable to the
Company  and  relating  to any action or  inaction  required  of the  Company in
connection  with any such  registration,  qualification  or compliance,  and the
Company will reimburse each such Registered  Holder and  controlling  person for
any  legal  and any  other  expenses  reasonably  incurred  in  connection  with
investigating or defending any such claim,  loss,  damage,  liability or action;
provided,  however,  that the Company will not be liable in any such case to the
extent that any such claim,  loss, damage or liability arises out of or is based
on any untrue statement or omission based upon written information  furnished to
the  Company  in an  instrument  duly  executed  by such  Registered  Holder  or
controlling  person  and  specifically  for  use in  such  prospectus  or  other
document.


                                     IGI, INC.


                                     /s/ Edward B. Hager
                                     --------------------------------
                                     By: Edward B. Hager
                                     Title: Chief Executive Officer


                                      -16-



                                                                       EXHIBIT I


                                  PURCHASE FORM


To:_________________                                          Dated:____________


     The  undersigned,  pursuant  to the  provisions  set forth in the  attached
Warrant (No.  ___),  hereby  irrevocably  elects to purchase _____ shares of the
Common Stock covered by such Warrant.  The undersigned herewith makes payment of
$____________, representing the full Exercise Price for such shares at the price
per share  provided for in such  Warrant.  Such payment takes the form of (check
applicable box or boxes):

[_]  $______ in lawful money of the United States; and/or

[_]  The  cancellation of such portion of the attached Warrant as is exercisable
     for a total of _____  Warrant  Shares  (using a Fair Market Value of $_____
     per share for purposes of this calculation).


Signature:_____________________

                                                  Address:______________________

                                                          ______________________


                                      -17-



                                                                      EXHIBIT II


                                 ASSIGNMENT FORM


     FOR VALUE RECEIVED,  ________________________________________ hereby sells,
assigns and  transfers all of the rights of the  undersigned  under the attached
Warrant (No.  ____) with respect to the number of shares of Common Stock covered
thereby set forth below, unto:

Name of Assignee                     Address                       No. of Shares
- ----------------                     -------                       -------------



Dated:_____________________                Signature:___________________________

Dated:_____________________                Witness:_____________________________