As filed with the Securities and Exchange Commission
                                on May 26, 1999
                                                   Registration No. 333-________

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                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549

                                    FORM S-8
                          REGISTRATION STATEMENT UNDER
                           THE SECURITIES ACT OF 1933

                                    IGI, INC.
             (Exact Name of Registrant as Specified in its Charter)

           Delaware                                             01-0355758
(State or Other Jurisdiction of                              (I.R.S. Employer
Incorporation or Organization)                            Identification Number)

Wheat Road & Lincoln Avenue, Buena, New Jersey                     08310
   (Address of Principal Executive Offices)                      (Zip Code)

                                    IGI, INC.
                        1999 EMPLOYEE STOCK PURCHASE PLAN
                            (Full Title of the Plan)

                              Edward B. Hager, M.D.
                             Chief Executive Officer
                                    IGI, Inc.
                           Wheat Road & Lincoln Avenue
                             Buena, New Jersey 08310
                     (Name and Address of Agent for Service)

                                 (609) 697-1441
          (Telephone Number, Including Area Code, of Agent For Service)

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                                   CALCULATION OF REGISTRATION FEE
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Title of Securities      Amount to be       Offering Price          Aggregate           Amount of
 to be Registered         Registered           Per Share         Offering Price      Registration Fee
- -----------------------------------------------------------------------------------------------------
                                                                           
   Common Stock,        300,000 shares      $1.625 (1)          $487,500 (1)           $136.00
  $.01 par value
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(1)  Estimated solely for the purpose of calculating the registration fee, and
     based upon the average of the reported high and low prices of the
     Registrant's Common Stock on the American Stock Exchange on May 24, 1999
     in accordance with Rules 457(c) and 457(h) of the Securities Act of 1933.







PART I. INFORMATION REQUIRED IN THE SECTION 10(a) PROSPECTUS

     The information required by Part I is included in documents sent or given
to participants in the Registrant's 1999 Employee Stock Purchase Plan pursuant
to Rule 428(b)(1) of the Securities Act of 1933, as amended (the "Securities
Act").

PART II. INFORMATION REQUIRED IN THE REGISTRATION STATEMENT

     Item 3. Incorporation of Certain Documents by Reference

     The Registrant is subject to the informational and reporting requirements
of Sections 13(a), 13(c), 14 and 15(d) of the Securities Exchange Act of 1934,
as amended (the "Exchange Act"), and, in accordance therewith, files reports,
proxy statements and other information with the Securities and Exchange
Commission (the "Commission"). The following documents, which are filed with the
Commission, are incorporated in this Registration Statement by reference:

          (1) The Registrant's latest annual report filed pursuant to Section
     13(a) or 15(d) of the Exchange Act or the latest prospectus filed pursuant
     to Rule 424(b) under the Securities Act that contains audited financial
     statements for the Registrant's latest fiscal year for which such
     statements have been filed.

          (2) All other reports filed pursuant to Section 13(a) or 15(d) of the
     Exchange Act since the end of the fiscal year covered by the document
     referred to in (1) above.

          (3) The description of the Common Stock, $.01 par value per share (the
     "Common Stock"), contained in a registration statement filed under the
     Exchange Act, including any amendment or report filed for the purpose of
     updating such description.

     All documents subsequently filed by the Registrant pursuant to Sections
13(a), 13(c), 14 and 15(d) of the Exchange Act, prior to the filing of a
post-effective amendment which indicates that all shares of Common Stock offered
hereby have been sold or which deregisters all shares of Common Stock then
remaining unsold, shall be deemed to be incorporated by reference herein and to
be part hereof from the date of the filing of such documents.


     Item 4. Description of Securities

          Not applicable.

     Item 5. Interests of Named Experts and Counsel


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          Not applicable.

     Item 6. Indemnification of Directors and Officers

     Section 145 of the General Corporation Law of the State of Delaware
provides that a corporation has the power to indemnify a director, officer,
employee or agent of the corporation and certain other persons serving at the
request of the corporation in related capacities against amounts paid and
expenses incurred in connection with an action or proceeding to which he is or
is threatened to be made a party by reason of such position, if such person
shall have acted in good faith and in a manner he reasonably believed to be in
or not opposed to the best interests of the corporation, and, in any criminal
proceeding, if such person had no reasonable cause to believe his conduct was
unlawful, provided that, in the case of actions brought by or in the right of
the corporation, no indemnification shall be made with respect to any matter as
to which such person shall have been adjudged to be liable to the corporation
unless and only to the extent that the adjudicating court determines that such
indemnification is proper under the circumstances. The Registrant's Certificate
of Incorporation, as amended, provides that the Registrant shall indemnify any
and all persons whom it shall have the power to indemnify under Section 145 to
the fullest extent permitted by the Delaware General Corporation Law.

     The Registrant has a directors and officers liability policy that insures
the Registrant's officers and directors against certain liabilities.

     Item 7. Exemption from Registration Claimed

          Not applicable.

     Item 8. Exhibits

          The Exhibit Index immediately preceding the exhibits is incorporated
     herein by reference.

     Item 9. Undertakings

     1.   The Registrant hereby undertakes:

          (1) To file, during any period in which offers or sales are being
     made, a post-effective amendment to this Registration Statement:

               (i) To include any prospectus required by Section 10(a)(3) of the
          Securities Act;


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               (ii) To reflect in the prospectus any facts or events arising
          after the effective date of this Registration Statement (or the most
          recent post-effective amendment thereof) which, individually or in the
          aggregate, represent a fundamental change in the information set forth
          in this Registration Statement. Notwithstanding the foregoing, any
          increase or decrease in volume of securities offered (if the total
          dollar value of securities offered would not exceed that which was
          registered) and any deviation from the low or high end of the
          estimated maximum offering range may be reflected in the form of
          prospectus filed with the Securities and Exchange Commission pursuant
          to Rule 424(b) if, in the aggregate, the changes in volume and price
          represent no more than a 20 percent change in the maximum aggregate
          offering price set forth in the "Calculation of Registration Fee"
          table in the effective registration statement;

               (iii) To include any material information with respect to the
          plan of distribution not previously disclosed in this Registration
          Statement or any material change to such information in this
          Registration Statement;

provided, however, that paragraphs (1)(i) and (1)(ii) do not apply if the
information required to be included in a post-effective amendment by those
paragraphs is contained in periodic reports filed with or furnished to the
Commission by the Registrant pursuant to Section 13 or Section 15(d) of the
Exchange Act that are incorporated by reference in this Registration Statement.

          (2) That, for the purpose of determining any liability under the
     Securities Act, each such post-effective amendment shall be deemed to be a
     new Registration Statement relating to the securities offered therein, and
     the offering of such securities at that time shall be deemed to be the
     initial bona fide offering thereof.

          (3) To remove from registration by means of a post-effective amendment
     any of the securities being registered which remain unsold at the
     termination of the offering.

     2. The Registrant hereby undertakes that, for purposes of determining any
liability under the Securities Act, each filing of the Registrant's annual
report pursuant to Section 13(a) or Section 15(d) of the Exchange Act (and,
where applicable, each filing of an employee benefit plan's annual report
pursuant to Section 15(d) of the Exchange Act) that is incorporated by reference
in the Registration Statement shall be deemed to be a new Registration Statement
relating to the securities offered therein, and the offering of such securities
at that time shall be deemed to be the initial bona fide offering thereof.


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     3. Insofar as indemnification for liabilities arising under the Securities
Act may be permitted to directors, officers and controlling persons of the
Registrant pursuant to the foregoing provisions, or otherwise, the Registrant
has been advised that in the opinion of the Commission such indemnification is
against public policy as expressed in the Securities Act and is, therefore,
unenforceable. In the event that a claim for indemnification against such
liabilities (other than the payment by the Registrant of expenses incurred or
paid by a director, officer or controlling person of the Registrant in the
successful defense of any action, suit or proceeding) is asserted by such
director, officer or controlling person in connection with the securities being
registered, the Registrant will, unless in the opinion of its counsel the matter
has been settled by controlling precedent, submit to a court of appropriate
jurisdiction the question whether such indemnification by it is against public
policy as expressed in the Act and will be governed by the final adjudication of
such issue.


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                                   SIGNATURES

     Pursuant to the requirements of the Securities Act of 1933, the Registrant
certifies that it has reasonable grounds to believe that it meets all of the
requirements for filing on Form S-8 and has duly caused this Registration
Statement to be signed on its behalf by the undersigned, thereunto duly
authorized, in Buena, New Jersey on the 26th day of May, 1999.


                                        IGI, INC.


                                        /s/ Edward B. Hager, M.D.
                                        ------------------------------------
                                        Edward B. Hager, M.D.
                                        Chairman and Chief Executive Officer




                                POWER OF ATTORNEY

     We, the undersigned officers and directors of IGI, Inc., hereby severally
constitute and appoint Edward B. Hager, Robert E. McDaniel and Paul P. Brountas,
and each of them singly, our true and lawful attorneys with full power to them,
and each of them singly, to sign for us and in our names in the capacities
indicated below, the Registration Statement on Form S-8 filed herewith and any
and all subsequent amendments to said Registration Statement, and generally to
do all such things in our names and behalf in our capacities as officers and
directors to enable IGI, Inc. to comply with all requirements of the Securities
and Exchange Commission, hereby ratifying and confirming our signatures as they
may be signed by said attorneys, or any of them, to said Registration Statement
and any and all amendments thereto.


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     Pursuant to the requirements of the Securities Act of 1933, this
Registration Statement has been signed below by the following persons in the
capacities and on the dates indicated.


     Signature                             Title                         Date
     ---------                             -----                         ----

/s/ Edward B. Hager, M.D.             Chairman and Chief            May 26, 1999
- -----------------------------------   Executive Officer
Edward B. Hager, M.D.                 (Principal Executive
                                      Officer)

/s/ John F. Wall                      Senior Vice President and     May 26, 1999
- -----------------------------------   Chief Financial Officer
John F. Wall                          (Principal Financial and
                                      Accounting Officer)

                                      Director
- -----------------------------------
Terrence D. Daniels

/s/ Jane E. Hager                     Director                      May 26, 1999
- -----------------------------------
Jane E. Hager

/s/ Constantine L. Hampers, M.D.      Director                      May 26, 1999
- -----------------------------------
Constantine L. Hampers, M.D.

/s/ Terrence O'Donnell                Director                      May 26, 1999
- -----------------------------------
Terrence O'Donnell


/s/ Paul D. Paganucci                 Director                      May 26, 1999
- -----------------------------------
Paul D. Paganucci


/s/ Stephen J. Morris                 Director                      May 26, 1999
- -----------------------------------
Stephen J. Morris




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                                  Exhibit Index

Exhibit
Number            Description                                              Page
- ------            -----------                                              ----

4.1       Specimen stock certificate for shares of Common Stock,             *
          par value $.01 per share (incorporated by reference to
          Exhibit (4) to the Registrant's Annual Report on Form
          10-K for the fiscal year ended December 31, 1989, filed
          April 2, 1990)

5         Opinion of Hale and Dorr LLP

23.1      Consent of PricewaterhouseCoopers LLP

23.2      Consent of Hale and Dorr LLP (included in Exhibit 5)

24        Power of Attorney (included on the signature pages of
          this Registration Statement)

          *Incorporated herein by reference.



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