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          As filed with the Securities and Exchange Commission on April 3, 2000
                                                 Registration No. 333-__________
================================================================================

                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549

                             ----------------------

                                    FORM S-8
                             REGISTRATION STATEMENT
                                      UNDER
                           THE SECURITIES ACT OF 1933


                        INTEGRATED SILICON SOLUTION, INC.
             (Exact name of Registrant as specified in its charter)


                                      
        Delaware                                        77-0199971
- ------------------------                 ---------------------------------------
(State of Incorporation)                 (I.R.S. Employer Identification Number)


                                2231 Lawson Lane
                  --------------------------------------------
                              Santa Clara, CA 95054
                    (Address of Principal Executive Offices)

                             ----------------------

                        1993 EMPLOYEE STOCK PURCHASE PLAN
                            (Full title of the plans)

                             ----------------------

                                 Gary L. Fischer
                           Executive Vice President &
                             Chief Financial Officer
                        INTEGRATED SILICON SOLUTION, INC.
                                2231 Lawson Lane
                              Santa Clara, CA 95054
                     (Name and address of agent for service)
                                 (408) 588-0800
          (Telephone number, including area code, of agent for service)

                             ----------------------

                                    Copy to:
                              J. Robert Suffoletta
                     WILSON SONSINI GOODRICH & ROSATI, P.C.
                               650 Page Mill Road
                           Palo Alto, California 94304
                            Telephone: (650) 493-9300



                                          CALCULATION OF REGISTRATION FEE
- -------------------------------------------------------------------------------------------------------------------
                                                   AMOUNT      PROPOSED MAXIMUM    PROPOSED MAXIMUM      AMOUNT OF
           TITLE SECURITIES TO                     TO BE        OFFERING PRICE         AGGREGATE       REGISTRATION
              BE REGISTERED                      REGISTERED      PER SHARE(1)       OFFERING PRICE          FEE
- -------------------------------------------------------------------------------------------------------------------
                                                                                              
Common Stock to be issued under the 1993
   Employee Stock Purchase Plan                250,000 shares     $25.39375           $6,348,438          $ 1,873
                                    TOTAL:

- ---------------
(1)  Estimated in accordance with Rule 457(h) solely for the purpose of
     calculating the registration fee. The fee is based on $29.875, the average
     of the high and low prices per share of the Common Stock as reported on the
     Nasdaq National Market on March 23, 2000 multiplied by .85, as provided in
     the plan.

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                        INTEGRATED SILICON SOLUTION, INC.
                       REGISTRATION STATEMENT ON FORM S-8

                                     PART II

                 INFORMATION REQUIRED IN REGISTRATION STATEMENT

ITEM 3. INCORPORATION OF DOCUMENTS BY REFERENCE.

     There are hereby incorporated by reference in this Registration Statement
the following documents and information heretofore filed with the Securities and
Exchange Commission:

     1.   The Company's Annual Report on Form 10-K for the year ending September
30, 1999, filed pursuant to Section 13 of the Securities Exchange Act of 1934,
as amended (the "Exchange Act").

     2.   The Company's Quarterly Report on Form 10-Q for the quarter ending
December 31, 1999, filed pursuant to Section 13 of the Exchange Act.

     3.   The description of the Company's Common Stock contained in the
Company's Registration Statement on Form 8-A dated January 7, 1995, filed
pursuant to Section 12 of the Exchange Act, including any amendment or report
filed for the purpose of updating such description.

     All documents filed by the Company pursuant to Sections 13(a), 13(c), 14
and 15(d) of the Exchange Act on or after the date of this Registration
Statement and prior to the filing of a post-effective amendment which indicates
that all securities offered have been sold or which deregisters all securities
then remaining unsold shall be deemed to be incorporated by reference in this
Registration Statement and to be part hereof from the date of filing of such
documents.

ITEM 4. DESCRIPTION OF SECURITIES.

     Not applicable.

ITEM 5. INTERESTS OF NAMED EXPERTS AND COUNSEL.

     Counsel for the Company, Wilson Sonsini Goodrich & Rosati, P.C., 650 Page
Mill Road, Palo Alto, California 94304, has rendered an opinion as to the Common
Stock offered hereby. As of March 24, 2000, Jeffrey D. Saper, a member of Wilson
Sonsini Goodrich & Rosati, P.C. beneficially owned 20,459 shares of the
Company's Common Stock.

ITEM 6. INDEMNIFICATION OF DIRECTORS AND OFFICERS.

     The Company's Certificate of Incorporation limits the liability of
directors to the maximum extent permitted by Delaware law. Delaware law provides
that directors of a company will not be personally liable for monetary damages
for breach of their fiduciary duties as directors, except for liability (i) for
any breach of their duty of loyalty to the company or its stockholders, (ii) for
acts or omissions not in good faith or which involve intentional misconduct or
knowing violation of law, (iii) for unlawful payments or dividends or unlawful
stock repurchases or redemptions as provided Section 174 of Delaware General
Corporation Law or (iv) for transactions from which the director derived an
improper personal benefit.


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     The Company's Bylaws provide that the Company shall indemnify its officers
and directors and may indemnify its employees and other agents to the fullest
extent provided by Delaware law, including those circumstances where
indemnification would otherwise be discretionary under Delaware law. The Company
believes that indemnification under its Bylaws covers at least negligence on the
part of indemnified parties. The Bylaws authorize the use of indemnification
agreements and the Company has entered into such agreements with each of its
directors and officers.

     The Company carries officer and director liability insurance with respect
to certain matters, including matters arising under the Securities Act of 1933,
as amended (the "Securities Act").

     Delaware law does not permit a corporation to eliminate a director's duty
of care, and the provisions of the Company's Certificate of Incorporation have
no effect on the availability of equitable remedies such as injunction or
rescission, based upon a director's breach of the duty of care. Insofar as
indemnification for liabilities arising under the Securities Act may be
permitted to foregoing provisions and agreements, the Company has been informed
that in the opinion of the staff of the Commission such indemnification is
against public policy as expressed in the Securities Act and is therefore
unenforceable.

ITEM 7. EXEMPTION FROM REGISTRATION CLAIMED.

     Not Applicable.

ITEM 8. EXHIBITS.



EXHIBIT
NUMBER                                    DESCRIPTION
- -------        -----------------------------------------------------------------
            
  4.1          1993 Employee Stock Purchase Plan, as amended
  5.1          Opinion of counsel as to legality of securities being registered
 23.1          Consent of Ernst & Young LLP, Independent Auditors
 23.2          Consent of counsel (contained in Exhibit 5.1)
 24.1          Power of Attorney (see page II-4)



ITEM 9. UNDERTAKINGS.

     A.   The undersigned registrant hereby undertakes:

          (1)  To file, during any period in which offers or sales are being
made, a post-effective amendment to this registration statement to include any
material information with respect to the plan of distribution not previously
disclosed in the registration statement or any material change to such
information in the registration statement.

          (2)  That, for the purpose of determining any liability under the
Securities Act of 1933, as amended (the "Securities Act") each such
post-effective amendment shall be deemed to be a new registration statement
relating to the securities offered therein, and the offering of such securities
at that time shall be deemed to be the initial bona fide offering thereof.

          (3)  To remove from registration by means of a post-effective
amendment any of the securities being registered which remain unsold at the
termination of the offering.


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   4

     B.   The undersigned registrant hereby undertakes that, for purposes of
determining any liability under the Securities Act, each filing of the
registrant's annual report pursuant to Section 13(a) or Section 15(d) of the
Exchange Act (and, where applicable, each filing of an employee benefit plan's
annual report pursuant to Section 15(d) of the Exchange Act) that is
incorporated by reference in the registration statement shall be deemed to be a
new registration statement relating to the securities offered therein, and the
offering of such securities at that time shall be deemed to be the initial bona
fide offering thereof.

     C.   Insofar as indemnification for liabilities arising under the
Securities Act may be permitted to directors, officers and controlling persons
of the registrant pursuant to the foregoing provisions, or otherwise, the
registrant has been advised that in the opinion of the Securities and Exchange
Commission such indemnification is against public policy as expressed in the
Securities Act and is, therefore, unenforceable. In the event that a claim for
indemnification against such liabilities (other than the payment by the
registrant of expenses incurred or paid by a director, officer or controlling
person of the registrant in the successful defense of any action, suit or
proceeding) is asserted by such director, officer or controlling person in
connection with the securities being registered, the registrant will, unless in
the opinion of its counsel the matter has been settled by controlling precedent,
submit to a court of appropriate jurisdiction the question whether such
indemnification by it is against public policy as expressed in the Securities
Act and will be governed by the final adjudication of such issue.


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                                   SIGNATURES

     Pursuant to the requirements of the Securities Act, the registrant
certifies that it has reasonable grounds to believe that it meets all of the
requirements for filing on Form S-8 and has duly caused this Registration
Statement to be signed on its behalf by the undersigned, thereunto, duly
authorized, in the City of Santa Clara, State of California, on March 24, 2000.

                                        INTEGRATED SILICON SOLUTION, INC.

                                        By: /s/ JIMMY S.M. LEE
                                           -------------------------------------
                                           Jimmy S.M. Lee, President and Chief
                                           Executive Officer


                                POWER OF ATTORNEY

     KNOW ALL PERSONS BY THESE PRESENTS, that each person whose signature
appears below constitutes and appoints Jimmy S.M. Lee and Gary L. Fischer,
jointly and severally, his or her attorneys-in-fact, each with the power of
substitution, for him or her in any and all capacities, to sign any amendments
to this Registration Statement on Form S-8 and to file the same, with exhibits
thereto and other documents in connection therewith, with the Securities and
Exchange Commission, hereby ratifying and confirming all that each of said
attorneys-in-fact, or his substitution or substitutes, may do or cause to be
done by virtue hereof.

     Pursuant to the requirements of the Securities Act, this Registration
Statement has been signed on March 24, 2000 by the following persons in the
capacities indicated.



           SIGNATURE                                    TITLE
- -------------------------------    -----------------------------------------------
                                
/s/ JIMMY S.M. LEE
- -------------------------------    Director, President and Chief Executive Officer
Jimmy S.M. Lee                     (Principal Executive Officer)

/s/ GARY L. FISCHER                Executive Vice President and Chief Financial
- -------------------------------    Officer (Principal Financial and Principal
Gary L. Fischer                    Accounting Officer)

/s/ CHUN WIN WONG                  Director
- -------------------------------
Chun Win Wong

/s/ LIP-BU TAN                     Director
- -------------------------------
Lip-Bu Tan

/s/ PAULINE ALKER                  Director
- -------------------------------
Pauline Alker

/s/ HIDE L. TANIGAMI               Director
- -------------------------------
Hide L. Tanigami



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                                   SIGNATURES

Pursuant to the requirements of the Securities Act, the registrant certifies
that it has reasonable grounds to believe that it meets all of the requirements
for filing on Form S-8 and has duly caused this Registration Statement to be
signed on its behalf by the undersigned, thereunto, duly authorized, in the City
of Santa Clara, State of California, on March __, 2000.

                                        INTEGRATED SILICON SOLUTION, INC.

                                        By:
                                           -------------------------------------
                                           Jimmy S.M. Lee, President and Chief
                                           Executive Officer


                                POWER OF ATTORNEY

     KNOW ALL PERSONS BY THESE PRESENTS, that each person whose signature
appears below constitutes and appoints Jimmy S.M. Lee and Gary L. Fischer,
jointly and severally, his or her attorneys-in-fact, each with the power of
substitution, for him or her in any and all capacities, to sign any amendments
to this Registration Statement on Form S-8 and to file the same, with exhibits
thereto and other documents in connection therewith, with the Securities and
Exchange Commission, hereby ratifying and confirming all that each of said
attorneys-in-fact, or his substitution or substitutes, may do or cause to be
done by virtue hereof.

     Pursuant to the requirements of the Securities Act, this Registration
Statement has been signed on March __, 2000 by the following persons in the
capacities indicated.



           SIGNATURE                                    TITLE
- -------------------------------    -----------------------------------------------
                                

- -------------------------------    Director, President and Chief Executive Officer
Jimmy S.M. Lee                     (Principal Executive Officer)

                                   Executive Vice President and Chief Financial
- -------------------------------    Officer (Principal Financial and Principal
Gary L. Fischer                    Accounting Officer)

                                   Director
- -------------------------------
Chun Win Wong

                                   Director
- -------------------------------
Lip-Bu Tan

                                   Director
- -------------------------------
Pauline Alker

                                   Director
- -------------------------------
Hide L. Tanigami



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                                INDEX TO EXHIBITS



EXHIBIT
NUMBER                                    DESCRIPTION
- -------        -----------------------------------------------------------------
            
  4.1          1993 Employee Stock Purchase Plan, as amended
  5.1          Opinion of counsel as to legality of securities being registered
 23.1          Consent of Ernst & Young LLP, Independent Auditors
 23.2          Consent of counsel (contained in Exhibit 5.1)
 24.1          Power of Attorney (see page II-4)



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