Exhibit 99.1

                                  CERTIFICATION

        Pursuant to Section 906 of the Public Company Accounting Reform and
Investor Protection Act of 2002 (18 U.S.C.Section 1350, as adopted), Ernest
Mario, Ph.D., the Chief Executive Officer of IntraBiotics Pharmaceuticals, Inc.
(the "Company"), and Eric H. Bjerkholt, the Chief Financial Officer of the
Company, each hereby certifies that, to the best of his knowledge:

        1. The Company's Quarterly Report on Form 10-Q for the period ended
        September 30, 2002, to which this Certification is attached as Exhibit
        99.1 (the "Periodic Report"), fully complies with the requirements of
        Section 13(a) or Section 15(d) of the Securities Exchange Act of 1934,
        as amended; and

        2. The information contained in the Periodic Report fairly presents, in
        all material respects, the financial condition of the Company at the end
        of the period covered by the Periodic Report and results of operations
        of the Company for the period covered by the Periodic Report.


Dated:  November 14, 2002

/s/  Ernest Mario, Ph.D.                         /s/   Eric H. Bjerkholt
- -------------------------------                  -------------------------------
Ernest Mario, Ph.D.                              Eric H. Bjerkholt
Chief Executive Officer                          Chief Financial Officer