EXHIBIT 99.1

CONTACT:                                                   FOR IMMEDIATE RELEASE

Eric H. Bjerkholt (investors)
IntraBiotics Pharmaceuticals, Inc.
(650) 526-6840


     INTRABIOTICS TO LAUNCH PHASE II/III CLINICAL STUDY OF ISEGANAN HCL FOR
                     VENTILATOR-ASSOCIATED PNEUMONIA (VAP)

 HENRY J. FUCHS, MD PROMOTED TO CEO; UP TO $3.5MM FINANCING COMMITMENT SECURED,
                        SUBJECT TO SHAREHOLDER APPROVAL.

MOUNTAIN VIEW, CA - February 6, 2003. IntraBiotics Pharmaceuticals, Inc.
(NASDAQ: IBPI) today announced plans to launch a 500 patient Phase II/III
clinical study to investigate iseganan HCl in the prevention of
ventilator-associated pneumonia (VAP). The company recently concluded a
productive meeting with the Food and Drug Administration to discuss the
development of iseganan for VAP.

Ventilator-associated pneumonia is a common infection occurring among patients
in the intensive care unit. Patients who require artificial ventilation are
vulnerable to experiencing pneumonia as a consequence of the aspiration of
bacteria-laden saliva. Prior clinical trials using a variety of other
antibiotics have demonstrated that VAP can be prevented through prophylactic
decontamination of the oral cavity. Conventional antibiotics are not widely
prescribed to prevent VAP because of concerns for the development of antibiotic
resistance and because there are currently no approved therapeutics for the
prevention of VAP. As a consequence, patients who develop VAP incur extended
stays in the intensive care unit and increased hospital charges. In the United
States, over 400,000 patients are artificially ventilated each year and are
vulnerable to developing VAP because they require ventilation for at least 48
hours.

Iseganan is a novel antimicrobial peptide whose properties may be well suited
for use in preventing VAP. Iseganan kills a wide spectrum of bacteria known to
cause pneumonia. Additionally, iseganan has been shown to be well tolerated in
clinical studies in cancer patients, and to effect significant reductions in the
level of bacteria in the oral cavity of cancer patients as well as patients who
require artificial ventilation. In a previous Phase I/II study completed by
IntraBiotics in artificially ventilated patients, iseganan reduced the levels of
oral bacteria by more than 100-fold compared to pre-treatment baseline levels
after a single 9 mg oral-topical dose. Data from the coming Phase II/III trial
are expected in the second quarter of 2004.

In preparing for the upcoming launch of the Phase II/III clinical trial for VAP,
the company has secured up to $3.5 million of financing commitments, subject to
shareholder approval. When combined with existing cash, these proceeds are
expected to assure sufficient funding through the completion of the Phase II/III
VAP clinical trial and into the second half of 2004. The investors in the
financing include Tang Capital Partners, LP, Baker Brothers Investments and Dr.
Ernest Mario, the Company's Chairman. The financing will be in the form of
Series A Convertible Preferred Stock as well as warrants to purchase shares of
Common Stock and the company intends to file a proxy statement with the SEC as a
first step in the process of seeking shareholder approval for the transaction.

At the request of Dr. Mario, the Board of Directors has elected Henry J. Fuchs,
MD, to the position of Chief Executive Officer of the company. Previously, Dr.
Fuchs was President and Chief Operating Officer

of the company. Dr. Mario will continue as Chairman of the Board. "I felt it was
important for the company to be led by an expert clinician. I am pleased that
Dr. Fuchs has agreed to become the CEO to assure that our VAP clinical trial is
executed on schedule and within the planned budget. I look forward to continuing
my close association with IntraBiotics as Chairman of the Board," said Dr.
Mario.

IntraBiotics is also in the process of seeking shareholder approval to effect a
reverse split of its outstanding shares in the range of between 1-for-8 and
1-for-12, as may be determined by the Board after the shareholder approval, in
the effort to support the minimum bid price maintenance requirement for listing
on the Nasdaq National Market. The company expects to hold the shareholder
meeting to solicit the shareholder approval of the reverse stock split and the
financing, among other matters, late first quarter or early second quarter of
2003.

IntraBiotics will host a conference call and live web cast to discuss its
current operations and business plan and the terms of the financing. The
conference call and web cast is scheduled for Tuesday, February 11, 2003, at
11:00 a.m. ET / 10:00 a.m. CT / 9:00 a.m. MT / 8:00 a.m. PT.

The conference call can be accessed by dialing (913) 981-4912. Those who wish to
listen to the call may participate via live web cast at
www.shareholder.com/intrabiotics/medialist.cfm.

A replay of the teleconference will be available through February 14, 2003 and
can be accessed by dialing (719) 457-0820 or (888) 203-1112. The confirmation
code for the replay is 701844.

ABOUT INTRABIOTICS PHARMACEUTICALS, INC.

IntraBiotics Pharmaceuticals, Inc., is a biopharmaceutical company engaged in
the development of high-value anti-infectives, focused on solving medical
problems for patients who currently have few or no satisfactory alternatives.
Additional information is available at the company's website:
www.intrabiotics.com.

Certain statements in this press release contain forward-looking information and
are subject to risks and uncertainties, such as statements regarding product
development, clinical developments, the expected timing of clinical trial
completion, and projections of future expenses. As such, they are subject to the
occurrence of many events outside of IntraBiotics' control and are subject to
various risk factors that could cause IntraBiotics' results to differ materially
from those expressed in any forward-looking statement. The risk factors include,
without limitation, the inherent risks of product development failure;
uncertainty of the timing, cost, extent and results of clinical trials; and the
company's ability to raise capital through private or public financings when
needed or on acceptable terms. These and other risk factors are more fully
described in documents on file with the Securities and Exchange Commission
including, but not limited to, our Annual Report on Form 10-K for the year ended
December 31, 2001 and on Form 10-Q for the quarter ended September 30, 2002.

Additional Information about the Transactions and Where to Find It

IntraBiotics plans to file a proxy statement with the Securities and Exchange
Commission relating to a solicitation of proxies from its stockholders in
connection with a special meeting of stockholders of IntraBiotics to be held for
the purpose of voting on various matters including: (1) a reverse stock split of
the Company's outstanding common stock and (2) a potential private placement of
preferred stock to be issued to certain new and existing stockholders, including
Dr. Ernest Mario, the Chairman of IntraBiotics, and (3) certain other matters
(the "Transactions"). SECURITY HOLDERS ARE ADVISED TO READ THE PROXY STATEMENT
WHEN IT BECOMES AVAILABLE BECAUSE IT WILL CONTAIN IMPORTANT INFORMATION. The
proxy statement will be available for free at www.sec.gov. In addition,
investors and security holders may obtain free copies of the documents filed
with the SEC by IntraBiotics by contacting Joyce Bremer c/o IntraBiotics
Pharmaceuticals, Inc., P. O. Box 1720, Mountain View, California 94042, (650)
526-6800. You may also obtain a free copy of the proxy statement, when it
becomes available, by contacting Georgeson Shareholder Communications at (866)
216-0457.

IntraBiotics and its executive officers and directors may be deemed to be
participants in the solicitation of proxies from the stockholders of
IntraBiotics in favor of the transactions. A list of the names of IntraBiotics'
executive officers and directors, and a description of their respective
interests in IntraBiotics, are set forth in the proxy statement for IntraBiotics
2002 Annual Meeting of Stockholders, which was filed with the SEC on April 19,
2002, and in any documents subsequently filed by its directors and executive
officers under the Securities and Exchange Act of 1934, as amended.

If and to the extent that executive officers or directors of IntraBiotics will
receive any additional benefits in connection with the transactions that are
unknown as of the date of this filing, the details of such benefits will be
described in the proxy statement and security holders may obtain additional
information regarding the interests of IntraBiotics' executive officers and
directors in the transaction by reading the proxy statement when it becomes
available.