Exhibit 99.2

                            CERTIFICATION PURSUANT TO
                             18 U.S.C. SECTION 1350,
                             AS ADOPTED PURSUANT TO
                  SECTION 906 OF THE SARBANES-OXLEY ACT OF 2002


Pursuant to 18 U.S.C. Section 1350, as adopted pursuant to Section 906 of the
Sarbanes-Oxley Act of 2002, Remi Barbier, President and Chief Executive Officer
of Pain Therapeutics, Inc. (the "Company"), hereby certify that to the best of
my knowledge:

      1.    The Company's Annual Report on Form 10-K for the year ended December
            31, 2002, and to which this certification is attached as Exhibit
            99.1 (the "Annual Report"), fully complies with the requirements of
            Section 13 (a) or 15 (d) of the Securities Exchange Act of 1934, and

      2.    The information contained in the Annual Report fairly presents, in
            all material respects, the financial condition and results of
            operations of the Company.



Date:  March  17, 2003                    /s/ REMI BARBIER
                                          -------------------------------------
                                          Remi Barbier
                                          Chairman of the Board of Directors,
                                          President and Chief Executive Officer