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                                                                   EXHIBIT 10.31







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                         CALYPTE BIOMEDICAL CORPORATION


                       LOAN AND BRIDGE SECURITY AGREEMENT



________________________________________________________________________________







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                               TABLE OF CONTENTS



                                                                                                                       Page
                                                                                                                 
1.        DEFINITIONS AND CONSTRUCTION
          1.1       Definitions . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .  1
          1.2       Accounting Terms  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .  7

2.        LOAN AND TERMS OF PAYMENT . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .  7
          2.1       Bridge Facility . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .  7
          2.2       Interest Rates, Payments, and Calculations  . . . . . . . . . . . . . . . . . . . . . . . . . . . .  7
          2.3       Crediting Payments  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .  7
          2.4       Fees  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .  8
          2.5       Additional Costs  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .  8
          2.6       Term  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .  8

3.        CONDITIONS OF LOANS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .  8
          3.1       Conditions Precedent to Initial Advance . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .  8

4.        CREATION OF SECURITY INTEREST . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .  9

          4.1       Grant of Security Interest  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .  9
          4.2       Delivery of Additional Documentation Required . . . . . . . . . . . . . . . . . . . . . . . . . . .  9
          4.3       Right to Inspect  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .  9

5.        REPRESENTATIONS AND WARRANTIES  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .  9
          5.1       Due Organization and Qualification  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .  9
          5.2       Due Authorization; No Conflict  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 10
          5.3       No Prior Encumbrances . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 10
          5.4       Bona Fide Accounts  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 10
          5.5       Merchantable Inventory  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 10
          5.6       Name; Location of Chief Executive Office  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 10
          5.7       Litigation  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 10
          5.8       No Material Adverse Change in Financial Statements  . . . . . . . . . . . . . . . . . . . . . . . . 10
          5.9       Solvency  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 10
          5.10      Regulatory Compliance . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 10
          5.11      Environmental Condition . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 11
          5.12      Taxes . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 11
          5.13      Subsidiaries  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 11
          5.14      Government Consents . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 11
          5.15      Intellectual Property . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 11
          5.16      Full Disclosure . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 11

6.        AFFIRMATIVE COVENANTS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 11
          6.1       Good Standing . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 11
          6.2       Government Compliance . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 12
          6.3       Financial Statements, Reports, Certificates . . . . . . . . . . . . . . . . . . . . . . . . . . . . 12
          6.4       Inventory; Returns  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 12
          6.5       Taxes . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 12
          6.6       Insurance . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 12
          6.7       Principal Depository  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 13
          6.8       Cash and Cash Equivalents . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 13
          6.9       Further Assurances  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 13



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7.        NEGATIVE COVENANTS  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 13
          7.1       Dispositions  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 13
          7.2       Change in Business  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 13
          7.3       Mergers or Acquisitions . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 13
          7.4       Indebtedness  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 14
          7.5       Encumbrances  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 14
          7.6       Distributions . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 14
          7.7       Investments . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 14
          7.8       Transactions with Affiliates  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 14
          7.9       Subordinated Debt . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 14
          7.10      Inventory . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 14
          7.11      Compliance  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 14

8.        EVENTS OF DEFAULT . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 15
          8.1       Payment Default . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 15
          8.2       Covenant Default  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 15
          8.3       Material Adverse Change . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 15
          8.4       Attachment  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 15
          8.5       Insolvency  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 15
          8.6       Other Agreements  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 15
          8.7       Judgments . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 16
          8.8       Misrepresentations  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 16

9.        BANK'S RIGHTS AND REMEDIES. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 16
          9.1       Rights and Remedies . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 16
          9.2       Power of Attorney . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 17
          9.3       Accounts Collection . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 17
          9.4       Bank Expenses . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 17
          9.5       Bank's Liability for Collateral . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 17
          9.6       Remedies Cumulative . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 17
          9.7       Demand; Protest . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 18

10.       NOTICES . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 18

11.       CHOICE OF LAW AND VENUE; JURY TRIAL WAIVER. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 18

12.       GENERAL PROVISIONS. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 18
          12.1     Successors and Assigns . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 18
          12.2     Indemnification  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 19
          12.3     Time of Essence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 20
          12.4     Severability of Provisions . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 20
          12.5     Amendments in Writing, Integration . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 20
          12.6     Counterparts . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 20
          12.7     Survival . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 20
          12.8     Confidentiality  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 20






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         This LOAN AND SECURITY AGREEMENT is entered into as of December
8,1995, by and between SILICON VALLEY BANK ("Bank") and CALYPTE BIOMEDICAL
CORPORATION ("Borrower").


                                    RECITALS

         Borrower wishes to obtain credit from Bank, and Bank desires to extend
credit to Borrower.  This Agreement sets forth the terms on which Bank will
advance credit to Borrower, and Borrower will repay the amounts owing to Bank.


                                   AGREEMENT

         The parties agree as follows:

         1.       DEFINITIONS AND CONSTRUCTION

                 1.1      Definitions.  As used in this Agreement, the
following terms shall have the following definitions:

                 "Accounts" means all presently existing and hereafter arising
accounts, contract rights, and all other forms of obligations owing to Borrower
arising out of the sale or lease of goods (including, without limitation, the
licensing of software and other technology) or the rendering of services by
Borrower, whether or not earned by performance, and any and all credit
insurance, guaranties, and other security therefor, as well as all merchandise
returned to or reclaimed by Borrower and Borrower's Books relating to any of
the foregoing.

                 "Advance" means a cash advance under the Bridge Facility.

                 "Affiliate" means, with respect to any Person, any Person that
owns or controls directly or indirectly such Person, any Person that controls
or is controlled by or is under common control with such Person, and each of
such Person's senior executive officers, directors, and partners.

                 "Bank Expenses" means all: reasonable costs or expenses
(including reasonable attorneys' fees and expenses) incurred in connection with
the preparation, negotiation, administration, and enforcement of the Loan
Documents; and Bank's reasonable attorneys' fees and expenses incurred in
amending, enforcing or defending the Loan Documents, whether or not suit is
brought.

                 "Borrower's Books" means all of Borrower's books and records
including: ledgers; records concerning Borrower's assets or liabilities, the
Collateral, business operations or financial condition; and all computer
programs, or tape files, and the equipment, containing such information.

                 "Bridge Facility" means the facility under which Borrower may
request Bank to issue a cash advance, as specified in Section 2.1 hereof.

                 "Business Day" means any day that is not a Saturday, Sunday,
or other day on which banks in the State of California are authorized or
required to close.

                 "Closing Date" means the date of this Agreement.

                 "Code" means the California Uniform Commercial Code.





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                 "Collateral" means the property described on Exhibit A
attached hereto.

                 "Committed Line" means Two Million Dollars ($2,000,000).

                 "Contingent Obligation" means, as applied to any Person, any
direct or indirect liability, contingent or otherwise, of that Person with
respect to (i) any indebtedness, lease, dividend, letter of credit or other
obligation of another, including, without limitation, any such obligation
directly or indirectly guaranteed, endorsed, co-made or discounted or sold with
recourse by that Person, or in respect of which that Person is otherwise
directly or indirectly liable; (ii) any obligations with respect to undrawn
letters of credit issued for the account of that Person; and (iii) all
obligations arising under any interest rate, currency or commodity swap
agreement, interest rate cap agreement, interest rate collar agreement, or
other agreement or arrangement designated to protect a Person against
fluctuation in interest rates, currency exchange rates or commodity prices;
provided, however, that the term "Contingent Obligation" shall not include
endorsements for collection or deposit in the ordinary course of business.  The
amount of any Contingent Obligation shall be deemed to be an amount equal to
the stated or determined amount of the primary obligation in respect of which
such Contingent Obligation is made or, if not stated or determinable, the
maximum reasonably anticipated liability in respect thereof as determined by
such Person in good faith; provided, however, that such amount shall not in any
event exceed the maximum amount of the obligations under the guarantee or other
support arrangement.

                 "Daily Balance" means the amount of the Obligations owed at
the end of a given day.

                 "Equipment" means all present and future machinery, equipment,
tenant improvements, furniture, fixtures, vehicles, tools, parts and
attachments in which Borrower has any interest.

                 "Equity Event" means the sale of Borrower's equity securities
pursuant to a registration statement filed under the Securities Act of 1933, as
amended.

                 "ERISA" means the Employment Retirement Income Security Act of
1974, as amended, and the regulations thereunder.

                 "GAAP" means generally accepted accounting principles as in
effect from time to time.

                 "Indebtedness" means (a) all indebtedness for borrowed money
or the deferred purchase price of property or services, including without
limitation reimbursement and other obligations with respect to surety bonds and
letters of credit, (b) all obligations evidenced by notes, bonds, debentures or
similar instruments, (c) all capital lease obligations and (d) all Contingent
Obligations.

                 "Insolvency Proceeding" means any proceeding commenced by or
against any person or entity under any provision of the United States
Bankruptcy Code, as amended, or under any other bankruptcy or insolvency law,
including assignments for the benefit of creditors, formal or informal
moratoria, compositions, extension generally with its creditors, or proceedings
seeking reorganization, arrangement, or other relief.

                 "Inventory" means all present and future inventory in which
Borrower has any interest, including merchandise, raw materials, parts,
supplies, packing and shipping materials, work in process and finished products
intended for sale or lease or to be furnished under a contract of service, of
every kind and description now or at any time hereafter owned by or in the
custody or possession, actual or constructive, of Borrower, including such
inventory as is temporarily out of its





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custody or possession or in transit and including any returns upon any accounts
or other proceeds, including insurance proceeds, resulting from the sale or
disposition of any of the foregoing and any documents of title representing any
of the above, and Borrower's Books relating to any of the foregoing.

                 "Investment" means any beneficial ownership of (including
stock, partnership interest or other securities) any Person, or any loan,
advance or capital contribution to any Person.

                 "IRC" means the Internal Revenue Code of 1986, as amended, and
the regulations thereunder.

                 " Lien" means any mortgage, lien, deed of trust, security
interest or other encumbrance.

                 "Loan Documents" means, collectively, this Agreement, any note
or notes executed by Borrower, and any other agreement entered into between
Borrower and Bank in connection with this Agreement, all as amended or extended
from time to time.

                 "Material Adverse Effect" means a material adverse effect on
(i) the business operations or condition (financial or otherwise) of Borrower
and its Subsidiaries taken as a whole or (ii) the ability of Borrower to repay
the Obligations, or (iii) the Collateral or the priority of Bank's lien on the
Collateral, taken as a whole.

                 "Maturity Date" means March 5, 1996.

                 "Negotiable Collateral" means all of Borrower's present and
future letters of credit of which it is a beneficiary, notes, drafts,
instruments, securities, documents of title, and chattel paper, and Borrower's
Books relating to any of the foregoing.

                 "Obligations" means all debt, principal, interest, Bank
Expenses and other amounts owed to the Bank by Borrower pursuant to this
Agreement or any other agreement, whether absolute or contingent, due or to
become due, now existing or hereafter arising, including any interest that
accrues after the commencement of an Insolvency Proceeding and including any
debt, liability, or obligation owing from Borrower to others that Bank may have
obtained by assignment or otherwise.

                 "Periodic Payments" means all installments or similar
recurring payments that Borrower may now or hereafter become obligated to pay
to Bank pursuant to the terms and provisions of any instrument, or agreement
now or hereafter in existence between Borrower and Bank.

                 "Permitted Indebtedness" means:

                 (a)      Indebtedness of Borrower in favor of Bank arising
under this Agreement or any other Loan Document;

                 (b)      Existing Indebtedness disclosed on the Schedule;

                 (c)      Subordinated Debt;

                 (d)      Indebtedness to trade creditors and with respect to
surety bonds and similar obligations incurred in the ordinary course of
business;

                 (e)      Indebtedness of any Subsidiary to Borrower and
Contingent Obligations of any Subsidiary with respect to obligations of
Borrower (provided that the primary obligations are not prohibited hereby);
provided that the incurrence of such Indebtedness or





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Contingent Obligations, as the case may be, does not result in a violation of
Section 7.7 as a consequence of the provisos set forth in paragraph (d) of the
definition of "Permitted Investments";

                 (f)      Indebtedness of Borrower to any Subsidiary and
Contingent Obligations of Borrower with respect to obligations of any
Subsidiary (provided that the primary obligations are not prohibited hereby),
and Indebtedness of any Subsidiary to any other Subsidiary and Contingent
Obligations of any Subsidiary with respect to obligations of any other
Subsidiary (provided that the primary obligations are not prohibited hereby);

                 (g)      Indebtedness secured by Permitted Liens;

                 (h)      Other Indebtedness not otherwise permitted by Section
7.4 not exceeding Fifty Thousand Dollars ($50,000) in the aggregate outstanding
at any time;

                 (i)      Indebtedness by Borrower and its Subsidiaries
consisting of guarantees (and other credit support) of the obligations of
vendors and suppliers of Borrower or its Subsidiaries in respect of
transactions entered into in the ordinary course of business provided that such
guarantees (and other credit support) shall not at any time exceed Twenty-Five
Thousand Dollars ($25,000);

                 (j)      Additional capital leases or indebtedness incurred
solely to purchase equipment which is secured in accordance with clause (c) of
"Permitted Liens" below and is not in excess of the lesser of the purchase
price of such equipment or the fair market value of such equipment on the date
of acquisition, provided that the outstanding principal amount of such
Indebtedness shall not exceed One Hundred Thousand Dollars ($100,000); and

                 (k)      Extensions, refinancing, modifications, amendments
and restatements of any of items of Permitted Indebtedness (a) through (i)
above, provided that the principal amount thereof is not increased or the terms
thereof are not modified to impose more burdensome terms upon Borrower or its
Subsidiary, as the case may be.

                 "Permitted Investment" means:

                 (a)      Investments existing on the Closing Date disclosed in
the Schedule;

                 (b)      (i) marketable direct obligations issued or
unconditionally guaranteed by the United States of America or any agency or any
State thereof maturing within one (1) year from the date of acquisition
thereof, (ii) commercial paper maturing no more than one (1) year from the date
of creation thereof and currently having the highest rating obtainable from
either Standard & Poor's Corporation or Moody's Investors Service, Inc., and
(iii) certificates of deposit maturing no more than one (1) year from the date
of investment therein issued by Bank;

                 (c)      Investments consisting of the endorsement of
negotiable instruments for deposit or collection or similar transactions in the
ordinary course of business;

                 (d)      Investments (whether consisting of the purchase of
securities, loans, capital contributions, or otherwise) of Subsidiaries in or
to other Subsidiaries or in Borrower;

                 (e)      Investments consisting of receivables owing to
Borrower or its Subsidiaries by Persons and advances to customers or suppliers,
in each case, if created, acquired or made in the ordinary course of business;
provided that this paragraph (f) shall not apply to Investments owing by
Subsidiaries to Borrower;





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                 (f)      Investments consisting of (i) compensation of
employees, officers and directors of Borrower or its Subsidiaries so long as
the Board of Directors of Borrower determines that such compensation is in the
best interests of Borrower, (ii) travel advances, employee relocation loans and
other employee loans and advances in the ordinary course of business; (iii)
loans to employees, officers or directors relating to the purchase of equity
securities of Borrower or its Subsidiaries, (iv) other loans to officers and
employees approved by the Board of Directors in an aggregate amount not in
excess of Fifty Thousand Dollars ($50,000) outstanding at any time;

                 (g)      Investments (including debt obligations) received in
connection with the bankruptcy or reorganization of customers or suppliers and
in settlement of delinquent obligations of, and other disputes with, customers
or suppliers, arising in the ordinary course of business;

                 (h)      Investments pursuant to or arising under currency
agreements or interest rate agreements;

                 (i)      Investments consisting of notes receivable of, or
prepaid royalties and other credit extensions to, customers and suppliers who
are not Affiliates in the ordinary course of business; provided that this
paragraph (i) shall not apply to Investments by Borrower in any Subsidiary;

                 (j)      Investments constituting acquisitions permitted under
Section 7.3;

                 (k)      Investments consisting of deposit accounts of
Borrower in which Bank has a Lien prior to any other Lien;

                 (l)      Investments consisting of deposit accounts of any
Subsidiaries maintained in the ordinary course of business;

                 (m)      Investments accepted in connection with Transfers
permitted by Section 7.1; and

                 (n)      Other Investments aggregating not in excess of
Twenty-Five Thousand Dollars ($25,000) at any time.

                  "Permitted Liens" means the following:

                 (a)      Any Liens existing as of the date hereof and
disclosed in the Schedule or arising under this Agreement or the other Loan
Documents;

                 (b)      Liens for taxes, fees, assessments or other
governmental charges or levies, either not delinquent or being contested in
good faith by appropriate proceedings, provided the same have no priority over
any of Bank's security interests;

                 (C)      Liens (i) upon or in any equipment acquired or held
by Borrower or any of its Subsidiaries to secure the purchase price of such
equipment or indebtedness incurred solely for the purpose of financing the
acquisition of such equipment, or (ii) existing on such equipment at the time
of its acquisition, provided that the Lien is confined solely to the property
so acquired and improvements thereon, and the proceeds of such equipment;

                 (d)     Leases or subleases and license and sublicenses 
granted to others in the ordinary course of Borrower's or its Subsidiaries' 
business not interfering in any material respect with the business of Borrower 
and its Subsidiaries taken as a whole, and any interest or title of a lessor, 
licensor or under any lease or license;





                                       5
   9
                 (e)      Liens on assets (including the proceeds thereof and
accessions thereto) that existed at the time such assets were acquired by
Borrower or any Subsidiary (including Liens on assets of any corporation that
existed at the time it became or becomes a Subsidiary);

                 (f)      Liens on Equipment leased by Borrower or any
Subsidiary pursuant to an operating lease in the ordinary course of business
(including proceeds thereof and accessions thereto) incurred solely for the
purpose of financing the lease of such Equipment;

                 (g)      Liens arising from judgments, decrees or attachments
in circumstances not constituting an Event of Default under Section 8.7;

                 (h)      Easements, reservations, rights-of-way, restrictions,
minor defects or irregularities in title and other similar charges or
encumbrances affecting real property not interfering in any material respect
with the ordinary conduct of the business of Borrower and its Subsidiaries,
taken as a whole;

                 (i)      Liens in favor of customs and revenue authorities
arising as a matter of law to secure payment of customs duties in connection
with the importation of goods;

                 (j)      Liens which constitute rights of set-off of a
customary nature or bankers' Liens with respect to amounts on deposit, whether
arising by operation of law or by contract, in connection with arrangements
entered into with banks in the ordinary course of business; provided that with
respect to Liens on amounts on deposit owned by Borrower, such Liens shall not
be prior to the Lien of Bank;

                 (k)      Liens on insurance proceeds in favor of insurance
companies granted solely as security for financed premiums;

                 (l)      Earn-out and royalty obligations existing on the date
hereof or entered into in connection with an acquisition permitted by Section
7.3; and

                 (m)      Liens incurred in connection with the extension,
renewal or refinancing of the indebtedness secured by Liens of the type
described in clauses (a) through (c) above, provided that any extension,
renewal or replacement Lien shall be limited to the property encumbered by the
existing Lien and the principal amount of the indebtedness being extended,
renewed or refinanced does not increase.

                 "Person" means any individual, sole proprietorship,
partnership, limited liability company, joint venture, trust, unincorporated
organization, association, corporation, institution, public benefit
corporation, firm, joint stock company, estate, entity or governmental agency.

                 "Prime Rate" means the variable rate of interest, per annum,
most recently announced by Bank, as its "prime rate," whether or not such
announced rate is the lowest rate available from Bank.

                 " Responsible Officer" means each of the Chief Executive
Officer, the Chief Financial Officer and the Controller of Borrower.

                 "Schedule" means the schedule of exceptions attached hereto,
if any.

                 "Subordinated Debt" means any debt incurred by Borrower that
is subordinated to the debt owing by Borrower to Bank on terms acceptable to
Bank (and identified as being such by Borrower and Bank).





                                       6
   10
                 "Subsidiary" means any corporation or partnership in which (i)
any general partnership interest or (ii) more than 50% of the stock of which by
the terms thereof ordinary voting power to elect the Board of Directors,
managers or trustees of the entity shall, at the time as of which any
determination is being made, is owned by Borrower, either directly or through
an Affiliate.

                 1.2      Accounting Terms.  All accounting terms not
specifically defined herein shall be construed in accordance with GAAP and all
calculations made hereunder shall be made in accordance with GAAP.  When used
herein, the terms "financial statements" shall include the notes and schedules
thereto.

         2.      LOAN AND TERMS OF PAYMENT

                 2.1      Bridge Facility.  Subject to and upon the terms and
conditions of this Agreement, Bank agrees to make one (1) Advance to Borrower
in an aggregate amount not to exceed the Committed Line.  Bank will credit the
amount of the Advance to Borrower's deposit account.  The Bridge Facility shall
terminate on the Maturity Date, at which time the entire principal amount of
the Advance, all accrued interest, and other amounts due under this Agreement
shall be immediately due and payable.

                 2.2      Interest Rates, Payments, and Calculations.

                          (a)     Interest Rate.  Except as set forth in
Section 2.2(b), the Advance shall bear interest, on the average Daily Balance,
at a rate equal to three and one half (3.5) percentage points above the Prime
Rate.

                          (b)     Default Rate.  All Obligations shall bear
interest, from and after the occurrence of an Event of Default, at a rate equal
to five (5) percentage points above the interest rate applicable immediately
prior to the occurrence of the Event of Default.

                          (c)     Payments.  Interest hereunder shall be due
and payable on the fifth calendar day of each month during the term hereof.
Bank shall, at its option, charge such interest, all Bank Expenses, and all
Periodic Payments against any of Borrower's deposit accounts or against the
Committed Line, in which case those amounts shall thereafter accrue interest at
the rate then applicable hereunder.  Any interest not paid when due shall be
compounded by becoming a part of the Obligations, and such interest shall
thereafter accrue interest at the rate then applicable hereunder.

                          (d)     Computation.  In the event the Prime Rate is
changed from time to time hereafter, the applicable rate of interest hereunder
shall be increased or decreased effective as of 12:01 a.m. on the day the Prime
Rate is changed, by an amount equal to such change in the Prime Rate.  All
interest chargeable under the Loan Documents shall be computed on the basis of
a three hundred sixty (360) day year for the actual number of days elapsed.

                 2.3      Crediting Payments.  Prior to the occurrence of an
Event of Default, Bank shall credit a wire transfer of funds, check or other
item of payment to such deposit account or Obligation as Borrower specifies.
After the occurrence of an Event of Default, the receipt by Bank of any wire
transfer of funds, check, or other item of payment shall be immediately applied
to conditionally reduce Obligations, but shall not be considered a payment on
account unless such payment is of immediately available federal funds or unless
and until such check or other item of payment is honored when presented for
payment.  Notwithstanding anything to the contrary contained herein, any
payment (other than a wire transfer of immediately available funds) received by
Bank after 12:00 noon California time shall be deemed to have been received by
Bank as of the opening of business on the immediately following Business Day.
Whenever any payment to Bank under the Loan Documents would otherwise be due
(except by reason of acceleration) on a date that is not a Business Day, such





                                       7
   11
payment shall instead be due on the next Business Day, and additional fees or
interest, as the case may be, shall accrue and be payable for the period of
such extension.

                 2.4      Fees.  Borrower shall pay to Bank the following:

                          (a)     Facility Fee.  A Facility Fee equal to Twenty
Thousand Dollars ($20,000), half of which has been paid and half of which shall
be paid on the date hereof.  The entire Facility Fee shall be fully earned and
nonrefundable on the date hereof.  An additional fee of Twenty Thousand Dollars
($20,000) shall be due on the Business Day following the Maturity Date, if all
Obligations have not been satisfied in full by the Maturity Date.

                          (b)     Bank Expenses.  Upon the date hereof, all
Bank Expenses incurred through the date hereof, including reasonable attorneys'
fees and expenses (not to exceed Four Thousand Dollars ($4,000)), and after the
date hereof, all Bank Expenses upon receipt of an invoice therefor;

                 2.5      Additional Costs.  In case any law, regulation, treaty
or official directive or the interpretation or application thereof by any court
or any governmental authority charged with the administration thereof or the
compliance with any guideline or request of any central bank or other
governmental authority (whether or not having the force of law):

                          (a)      subjects Bank to any tax with respect to
payments of principal or interest or any other amounts payable hereunder by
Borrower or otherwise with respect to the transactions contemplated hereby
(except for taxes on the overall net income of Bank imposed by the United States
of America or any political subdivision thereof);

                          (b)      imposes, modifies or deems applicable any
deposit insurance, reserve, special deposit or similar requirement against
assets held by, or deposits in or for the account of, or loans by, Bank; or

                          (c)      imposes upon Bank any other condition with
respect to its performance under this Agreement,

and the result of any of the foregoing is to increase the cost to Bank, reduce
the income receivable by Bank or impose any expense upon Bank with respect to
any loans, Bank shall notify Borrower thereof.  Borrower agrees to pay to Bank
the amount of such increase in cost, reduction in income or additional expense
as and when such cost, reduction or expense is incurred or determined, upon
presentation by Bank of a statement of the amount and setting forth Bank's
calculation thereof, all in reasonable detail, which statement shall be deemed
true and correct absent manifest error; provided, however, that the Borrower
shall not be liable for any such amount attributable to any period prior to 180
day prior to the date of such certificate.

                 2.6     Term.  Subject to Section 12.7, this Agreement shall
become effective upon the date hereof and shall continue in full force and
effect for a term ending on the Maturity Date.  Notwithstanding termination,
Bank's Lien on the Collateral shall remain in effect for so long as any
Obligations (excluding Obligations under Sections 2.5 and 12.2 to the extent
they remain inchoate at the time outstanding payment Obligations are paid in
full) are outstanding.

          3.     CONDITIONS OF LOANS

                 3.1     Conditions Precedent to Initial Advance.  The
obligation of Bank to make the Advance is subject to the condition precedent
that:





                                       8
   12
                          (a)      after due diligence inquiry conducted by Bank
at Borrower's expense, and upon completion of audits conducted by Bank at
Borrower's expense, there shall have been no discovery of any facts that in
Bank's sole discretion would have a Material Adverse Effect; and

                          (b)      Bank shall have received, in form and
substance satisfactory to Bank, the following:

                                   (i)     this Agreement;

                                   (ii)    a certificate of the Secretary of
Borrower with respect to incumbency and resolutions authorizing the execution
and delivery of this Agreement;

                                   (iii)   insurance certificate;

                                   (iv)    financing statement (Form UCC-1);

                                   (v)     payment of the fees and Bank Expenses
then due specified in Section 2.5 hereof; and

                                   (vi)    such other documents, and completion
of such other matters, as Bank may reasonably deem necessary or appropriate.

         4.      CREATION OF SECURITY INTEREST

                 4.1      Grant of Security Interest.  Borrower grants to Bank
a continuing security interest in all presently existing and hereafter acquired
or arising Collateral in order to secure prompt repayment of any and all
Obligations and in order to secure prompt performance by Borrower of each of
its covenants and duties under the Loan Documents.  Except as set forth in the
Schedule, such security interest constitutes a valid, first priority security
interest in the presently existing Collateral, and will constitute a valid,
first priority security interest in Collateral acquired after the date hereof,
in each case, to the extent that a security interest in such Collateral can be
perfected by the filing of a financing statement, in the case of Collateral
consisting of instruments, documents, chattel paper or certificated securities,
to the extent that Bank takes possession of such Collateral.

                 4.2      Delivery of Additional Documentation Required.
Borrower shall from time to time execute and deliver to Bank, at the request of
Bank, all Negotiable Collateral, all financing statements and other documents
that Bank may reasonably request, in form satisfactory to Bank, to perfect and
continue perfected Bank's security interests in the Collateral and in order to
fully consummate all of the transactions contemplated under the Loan Documents.

                 4.3      Right to Inspect.  Bank (through any of its officers,
employees, or agents) shall have the right, upon reasonable prior notice, from
time to time during Borrower's usual business hours, to inspect Borrower's
Books and to make copies thereof and to check, test, and appraise the
Collateral in order to verify Borrower's financial condition or the amount,
condition of, or any other matter relating to, the Collateral.

          5.     REPRESENTATIONS AND WARRANTIES

                 Borrower represents and warrants as follows:


                 5.1      Due Organization and Qualification.  Borrower and
each Subsidiary is a corporation duly existing and in good standing under the
laws of its state of incorporation and qualified and licensed to do business
in, and is in good standing in, any state in which the conduct of





                                       9
   13
its business or its ownership of property requires that it be so qualified
except for states as to which any failure so to qualify would not have a
Material Adverse Effect.

                 5.2      Due Authorization; No Conflict.  The execution,
delivery, and performance of the Loan Documents are within Borrower's powers,
have been duly authorized, and are not in conflict with nor constitute a breach
of any provision contained in Borrower's Certificate of Incorporation or
Bylaws, nor will they constitute an event of default under any material
agreement to which Borrower is a party or by which Borrower is bound.  Borrower
is not in default under any agreement to which it is a party or by which it is
bound, which default would reasonably be expected to have a Material Adverse
Effect.

                 5.3      No Prior Encumbrances.  Borrower has good and
indefeasible title to the Collateral, free and clear of Liens, except for
Permitted Liens.

                 5.4      Bona Fide Accounts.  The Accounts are bona fide
existing obligations.  The property giving rise to such Accounts has been
delivered to the account debtor or to the account debtor's agent for immediate
shipment to and unconditional acceptance by the account debtor.

                 5.5      Merchantable Inventory.  All Inventory is in all
material respects of good and marketable quality, free from all material
defects.

                 5.6      Name; Location of Chief Executive Office.  Except as
disclosed in the Schedule, Borrower has not done business under any name other
than that specified on the signature page hereof.  The chief executive office
of Borrower is located at the address indicated in Section 10 hereof.

                 5.7      Litigation.  Except as set forth in the Schedule,
there are no actions or proceedings pending (or, to Borrower's knowledge,
threatened) by or against Borrower or any Subsidiary before any court or
administrative agency in which a likely adverse decision would reasonably be
expected to have a Material Adverse Effect or a material adverse effect on
Borrower's interest or Bank's security interest in the Collateral.

                 5.8      No Material Adverse Change in Financial Statements.
All consolidated financial statements related to Borrower and any Subsidiary
that have been delivered by Borrower to Bank fairly present in all material
respects Borrower's consolidated financial condition as of the date thereof and
Borrower's consolidated results of operations for the period then ended.  There
has not been a material adverse change in the consolidated financial condition
of Borrower since the date of the most recent of such financial statements
submitted to Bank.

                 5.9      Solvency.  Borrower is solvent and able to pay its
debts (including trade debts) as they mature.

                 5.10     Regulatory Compliance.  Borrower and each Subsidiary
has met the minimum funding requirements of ERISA with respect to any employee
benefit plans subject to ERISA.  No event has occurred resulting from
Borrower's failure to comply with ERISA that is reasonably likely to result in
Borrower's incurring any liability that would reasonably be expected to have a
Material Adverse Effect.  Borrower is not an "investment company" or a company
"controlled" by an "investment company" within the meaning of the Investment
Company Act of 1940.  Borrower is not engaged principally, or as one of the
important activities, in the business of extending credit for the purpose of
purchasing or carrying margin stock (within the meaning of Regulations G, T and
U of the Board of Governors of the Federal Reserve System).  Borrower has
complied with all the provisions of the Federal Fair Labor Standards Act.
Borrower has not violated any statutes, laws, ordinances or rules applicable to
it, violation of which could have a Material Adverse Effect.





                                       10
   14
                 5.11     Environmental Condition.  None of Borrower's or any
Subsidiary's properties or assets has ever been used by Borrower or any
Subsidiary or, to the best of Borrower's knowledge, by previous owners or
operators, in the disposal of, or to produce, store, handle, treat, release, or
transport, any hazardous waste or hazardous substance other than in accordance
with applicable law; to the best of Borrower's knowledge, none of Borrower's
properties or assets has ever been designated or identified in any manner
pursuant to any environmental protection statute as a hazardous waste or
hazardous substance disposal site, or a candidate for closure pursuant to any
environmental protection statute; no lien arising under any environmental
protection statute has attached to any revenues or to any real or personal
property owned by Borrower or any Subsidiary; and neither Borrower nor any
Subsidiary has received a summons, citation, notice, or directive from the
Environmental Protection Agency or any other federal, state or other
governmental agency concerning any action or omission by Borrower or any
Subsidiary resulting in the releasing, or otherwise disposing of hazardous
waste or hazardous substances into the environment.

                 5.12     Taxes.  Borrower and each Subsidiary has filed or
caused to be filed all material tax returns required to be filed, and has paid,
or has made adequate provision for the payment of, all taxes reflected therein.

                 5.13     Subsidiaries.  Borrower does not own any stock,
partnership interest or other equity securities of any Person, except for
Permitted Investments.

                 5.14     Government Consents.  Borrower and each Subsidiary
has obtained all consents, approvals and authorizations of, made all
declarations or filings with, and given all notices to, all governmental
authorities that are necessary for the continued operation of Borrower's
business as currently conducted except where the failure to obtain any such
consent, approval or authorization, to make any such declaration or filing or
to given any such notice would not reasonably be expected to have Material
Adverse Effect.

                 5.15     Intellectual Property.  To Borrower's knowledge,
Borrower possesses and owns, free of any material infringement or other
material claims by third parties, all trademarks, trade names, copyrights,
patent rights, patents, licenses that are used in the conduct of its business
as now operated.  To Borrower's knowledge, there is no material infringement by
others of any trademark, trade name, trade secret, service mark, patent,
copyright, license or other intellectual property right of Borrower.

                 5.16     Full Disclosure.  No representation, warranty or
other statement made by Borrower in any certificate or written statement
furnished to Bank by Borrower in connection with the transactions contemplated
by this Agreement, taken as a whole, contains any untrue statement of a
material fact or omits to state a material fact necessary in order to make
the statements contained in such certificates or statements not misleading (it
being recognized by Bank that the projections and forecasts provided by
Borrower are not be viewed as facts and that actual results during the period
or periods covered by any such projections and forecasts may differ from the
projected or forecasted results).

          6.     AFFIRMATIVE COVENANTS

                 Borrower covenants and agrees that, until payment in full of
all outstanding Obligations, and for so long as Bank may have any commitment to
make an Advance hereunder, Borrower shall do all of the following:

                 6.1      Good Standing.  Borrower shall maintain or cause to
be maintained its and each of its Subsidiaries' corporate existence and good
standing in its jurisdiction of incorporation and maintain qualification in
each jurisdiction in which the failure to so qualify would reasonably be
expected to have a Material Adverse Effect.  Borrower shall maintain, and shall
cause each of its





                                       11
   15
Subsidiaries to maintain, in force all licenses, approvals and agreements, the
loss of which would reasonably be expected to have a Material Adverse Effect.

                 6.2      Government Compliance.  Borrower shall meet, and
shall cause each Subsidiary to meet, the minimum funding requirements of ERISA
with respect to any employee benefit plans subject to ERISA.  Borrower shall
comply, and shall cause each Subsidiary to comply, with all statutes, laws,
ordinances and government rules and regulations to which it is subject,
noncompliance with which could have a Material Adverse Effect or a material
adverse effect on the Collateral or the priority of Bank's Lien on the
Collateral.

                 6.3      Financial Statements, Reports, Certificates.
Borrower shall deliver to Bank: (a)  as soon as available, but in any event
within thirty (30) days after the end of each month, a company prepared
consolidated balance sheet and income statement covering Borrower's
consolidated operations during such period, certified by a Responsible Officer;
(b) as soon as available, but in any event within ninety (90) days after the
end of Borrower's fiscal year, audited consolidated financial statements of
Borrower prepared in accordance with GAAP, consistently applied, together with
an unqualified opinion on such financial statements of an independent certified
public accounting firm reasonably acceptable to Bank; (c) within five (5) days
upon becoming available, copies of all statements, reports and notices sent or
made available generally by Borrower to its security holders or to any holders
of Subordinated Debt and, to the extent applicable, all reports on Form 8-K,
10-K and 10-Q (without exhibits) filed with the Securities and Exchange
Commission; (d) promptly upon receipt of notice thereof, a report of any legal
actions pending or threatened against Borrower or any Subsidiary that would
reasonably be expected to result in damages or costs to Borrower or any
Subsidiary of One Hundred Thousand Dollars ($100,000) or more; and (e) such
budgets, sales projections, operating plans or other financial information as
Bank may reasonably request from time to time.

         Borrower shall deliver to Bank with the monthly financial statements a
Compliance Certificate signed by a Responsible Officer in substantially the
form of Exhibit B hereto.

                 6.4      Inventory; Returns.  Borrower shall keep all
Inventory in good and marketable condition, free from all material defects.
Returns and allowances, if any, as between Borrower and its account debtors
shall be on the same basis and in accordance with the usual customary practices
of Borrower, as they exist at the time of the execution and delivery of this
Agreement.  Borrower shall promptly notify Bank of all returns and recoveries
and of all disputes and claims, where the return, recovery, dispute or claim
involves more than Fifty Thousand Dollars ($50,000).

                 6.5      Taxes.  Borrower shall make, and shall cause each
Subsidiary to make, due and timely payment or deposit of all material federal,
state, and local taxes, assessments, or contributions required of it by law,
and will execute and deliver to Bank, on demand, appropriate certificates
attesting to the payment or deposit thereof; and Borrower will make, and will
cause each Subsidiary to make, timely payment or deposit of all material tax
payments and withholding taxes required of it by applicable laws, including,
but not limited to, those laws concerning F.I.C.A., F.U.T.A., state disability,
and local, state, and federal income taxes, and will, upon request, furnish
Bank with proof satisfactory to Bank indicating that Borrower or a Subsidiary
has made such payments or deposits; provided that Borrower or a Subsidiary need
not make any payment if the amount or validity of such payment is contested in
good faith by appropriate proceedings and is reserved against (to the extent
required by GAAP) by Borrower.

                 6.6      Insurance.

                          (a)     Borrower, at its expense, shall keep the
Collateral insured against loss or damage by fire, theft, explosion,
sprinklers, and all other hazards and risks, and in such amounts, as ordinarily
insured against by other owners in similar businesses conducted in the
locations where





                                       12
   16
Borrower's business is conducted on the date hereof.  Borrower shall also
maintain insurance relating to Borrower's ownership and use of the Collateral
in amounts and of a type that are customary to businesses similar to
Borrower's.

                          (b)     All such policies of insurance shall be in
such form, with such companies, and in such amounts as reasonably satisfactory
to Bank.  All such policies of property insurance shall contain a lender's loss
payable endorsement, in a form satisfactory to Bank, showing Bank as an
additional loss payee thereof and all liability insurance policies shall show
the Bank as an additional insured, and shall specify that the insurer must give
at least twenty (20) days notice to Bank before canceling its policy for any
reason.  Upon Bank's request, Borrower shall deliver to Bank certified copies
of such policies of insurance and evidence of the payments of all premiums
therefor.  So long as no Event of Default has occurred and is continuing,
Borrower shall have the option of applying the proceeds of any casualty policy
to the replacement or repair of destroyed or damaged property; provided, that
after the occurrence and during the continuance of an Event of Default, all
proceeds payable under any such casualty policy shall, at the option of Bank,
be payable to Bank for application to the Obligations.

                 6.7      Principal Depository.  Borrower shall maintain its
principal depository and operating accounts with Bank.

                 6.8      Cash and Cash Equivalents.  Beginning November 30,
1995, Borrower shall maintain as of the last day of each month during the term
of this Agreement a balance of cash and cash equivalents of not less than Seven
Hundred Thousand Dollars ($700,000).

                 6.9      Further Assurances.  At any time and from time to
time Borrower shall execute and deliver such further instruments and take such
further action as may reasonably be requested by Bank to effect the purposes of
this Agreement.

         7.      NEGATIVE COVENANTS

                 Borrower covenants and agrees that, without the prior written
consent of Bank, which Bank may grant or withhold in its sole discretion, so
long as any credit hereunder shall be available and until payment in full of
the outstanding Obligations or for so long as Bank may have any commitment to
make any Advances, Borrower will not do any of the following:

                 7.1      Dispositions.  Convey, sell, lease, transfer or
otherwise dispose of (collectively, a "Transfer"), or permit any of its
Subsidiaries to Transfer, all or any part of its business or property, other
than: (i) Transfers of Inventory in the ordinary course of business; (ii)
Transfers of non-exclusive licenses and similar arrangements for the use of the
property of Borrower or its Subsidiaries; or (iii) Transfers of worn-out or
obsolete Equipment and (iv) Transfers which constitute liquidation of
Investments permitted under Section 7.7.

                 7.2      Change in Business.  Engage in any business, or
permit any of its Subsidiaries to engage in any business, other than the
businesses currently engaged in by Borrower and any business substantially
similar or related thereto (or incidental thereto), or suffer a material change
in Borrower's ownership, other than the sale by Borrower of equity securities
of Borrower.  Borrower will not, without thirty (30) days prior written
notification to Bank, relocate its chief executive office.

                 7.3      Mergers or Acquisitions.  Merge or consolidate, or
permit any of its Subsidiaries to merge or consolidate, with or into any other
business organization, or acquire, or permit any of its Subsidiaries to
acquire, all or substantially all of the capital stock or property of another
Person; provided, however, that this Section 7.3 shall not apply to
transactions among Borrower and its Subsidiaries in which Borrower is the
surviving entity or among its Subsidiaries, provided no Event of Default exists
before or immediately after giving effect to such transactions.





                                       13
   17
                 7.4      Indebtedness.  Create, incur, assume or be or remain
liable with respect to any Indebtedness, or permit any Subsidiary so to do,
other than Permitted Indebtedness.

                 7.5      Encumbrances.  Create, incur, assume or suffer to
exist any Lien with respect to any of its property (including, without
limitation, intellectual property), or assign or otherwise convey any right to
receive income, including the sale of any Accounts, or permit any of its
Subsidiaries so to do, except for Permitted Liens.

                 7.6      Distributions.  Pay any dividends or make any other
distribution or payment on account of or in redemption, retirement or purchase
of any capital stock except for repurchases of stock from former employees of
Borrower in accordance with the terms of repurchase or similar agreements
between Borrower and such employees in an aggregate amount in any fiscal year
not to exceed Fifty Thousand Dollars ($50,000).

                 7.7      Investments.  Directly or indirectly acquire or own,
or make any Investment in or to any Person, or permit any of its Subsidiaries
so to do, other than Permitted Investments.

                 7.8      Transactions with Affiliates.  Directly or indirectly
enter into or permit to exist any material transaction with any Affiliate of
Borrower except (i) for transactions that are in the ordinary course of
Borrower's business, upon fair and reasonable terms that are no less favorable
to Borrower than would be obtained in an arm's length transaction with a
nonaffiliated Person, (ii) transactions with a Subsidiary that are upon fair
and reasonable terms and transactions constituting Permitted Investments, and
(iii) transactions with Affiliates who in addition to being Affiliates are also
customers of the Borrower and who receive, as customers, terms more favorable
than the general public.

                 7.9      Subordinated Debt.  Make any payment in respect of
any Subordinated Debt, or permit any of its Subsidiaries to make any such
payment, except in compliance with the terms of such Subordinated Debt, or
amend any provision contained in any documentation relating to the Subordinated
Debt without Bank's prior written consent.

                 7.10     Inventory.  Store the Inventory with a bailee,
warehouseman, or similar party unless Bank has received a pledge of the
warehouse receipt covering such Inventory.  Except for Inventory sold in the
ordinary course of business and except for such other locations as Bank may
approve in writing, Borrower shall keep the Inventory only at the location set
forth in Section 10 hereof or in the Schedule and such other locations of which
Borrower gives Bank prior written notice and as to which Borrower signs and
files a financing statement where needed to perfect Bank's security interest.

         7.11    Compliance.  Become an "investment company" or become
controlled by an "investment company," within the meaning of the Investment
Company Act of 1940, or become principally engaged in, or undertake as one of
its important activities, the business of extending credit for the purpose of
purchasing or carrying margin stock, or use the proceeds of any Advance for
such purpose.  Fail to meet the minimum funding requirements of ERISA, permit a
Reportable Event or Prohibited Transaction, as defined in ERISA, to occur, fail
to comply with the Federal Fair Labor Standards Act or violate any law or
regulation, which violation could have a Material Adverse Effect or a material
adverse effect on the Collateral or the priority of Bank's Lien on the
Collateral, or permit any of its Subsidiaries to do any of the foregoing.





                                       14
   18
         8.      EVENTS OF DEFAULT

                 Any one or more of the following events shall constitute an
Event of Default by Borrower under this Agreement:

                 8.1      Payment Default.  If Borrower fails to pay the
principal of, or any interest on, any Advances when due and payable; or fails
to pay any portion of any other Obligations not constituting such principal or
interest, including without limitation Bank Expenses, within thirty (30) days
of receipt by Borrower of an invoice therefor;

                 8.2      Covenant Default.  If Borrower fails to perform any
obligation under any of Sections 6.7 or 6.8 or violates any of the covenants
contained in Article 7 of this Agreement, or fails or neglects to perform,
keep, or observe any other material term, provision, condition, covenant, or
agreement contained in this Agreement, in any of the Loan Documents, or in any
other present or future agreement between Borrower and Bank and as to any
default under such other term, provision, condition, covenant or agreement that
can be cured, has failed to cure such default within thirty (30) days after
Borrower receives notice thereof or any Responsible Officer of Borrower becomes
aware thereof; provided, however, that if the default cannot by its nature be
cured within the ten (10) day period or cannot after diligent attempts by
Borrower be cured within such ten (10) day period, and such default is likely
to be cured within a reasonable time, then Borrower shall have an additional
reasonable period (which shall not in any case exceed thirty (30) days) to
attempt to cure such default, and within such reasonable time period the
failure to have cured such default shall not be deemed an Event of Default
(provided that no Advances will be required to be made during such cure
period);

                 8.3      Material Adverse Change.  If there occurs a material
adverse change in Borrower's business or financial condition, or if there is a
material impairment of the prospect of repayment of any portion of the
Obligations or a material impairment of the value or priority of Bank's
security interests in the Collateral, and Borrower fails to cure such default
within ten (10) days after Borrower receives notice thereof.

                 8.4      Attachment.  If any material portion of Borrower's
assets is attached, seized, subjected to a writ or distress warrant, or is
levied upon, or comes into the possession of any trustee, receiver or person
acting in a similar capacity and such attachment, seizure, writ or distress
warrant or levy has not been removed, discharged or rescinded within thirty
(30) days, or if Borrower is enjoined, restrained, or in any way prevented by
court order from continuing to conduct all or any material part of its business
affairs, or if a judgment or other claim becomes a lien or encumbrance upon any
material portion of Borrower's assets, or if a notice of lien, levy, or
assessment is filed of record with respect to any of Borrower's assets by the
United States Government, or any department, agency, or instrumentality
thereof, or by any state, county, municipal, or governmental agency, and the
same is not paid within thirty (30) days after Borrower receives notice
thereof, provided that none of the foregoing shall constitute an Event of
Default where such action or event is stayed or an adequate bond has been
posted pending a good faith contest by Borrower (provided that no Advances will
be required to be made during such cure period);

                 8.5      Insolvency.  If Borrower becomes insolvent, or if an
Insolvency Proceeding is commenced by Borrower, or if an Insolvency Proceeding
is commenced against Borrower and is not dismissed or stayed within thirty (30)
days (provided that no Advances will be made prior to the dismissal of such
Insolvency Proceeding);

                 8.6      Other Agreements.  If there is a default in any
agreement to which Borrower is a party with a third party or parties resulting
in a right by such third party or parties, whether or not exercised, to
accelerate the maturity of any Indebtedness in an amount in excess of Fifty
Thousand Dollars ($50,000) or that would reasonably be expected to have a
Material Adverse Effect;





                                       15
   19
                 8.7      Judgments.  If a judgment or judgments for the
payment of money in an amount, individually or in the aggregate, of at least
One Hundred Thousand Dollars ($100,000) shall be rendered against Borrower and
shall remain unsatisfied and unstayed for a period of forty-five (45) days
(provided that no Advances will be made prior to the satisfaction or stay of
such judgment); or

                 8.8      Misrepresentations.  If any material
misrepresentation or material misstatement exists now or hereafter in any
warranty or representation set forth herein or in any certificate delivered to
Bank by any Responsible Officer pursuant to this Agreement or to induce Bank to
enter into this Agreement or any other Loan Document and, as to any such
misrepresentation or misstatement that can be cured, Borrower fails to make
that cure within ten (10) days after Borrower receives notice thereof.

         9.      BANK'S RIGHTS AND REMEDIES

                 9.1      Rights and Remedies.  Upon the occurrence and during
the continuance of an Event of Default, Bank may, at its election, without
notice of its election and without demand, do any one or more of the following,
all of which are authorized by Borrower:

                          (a)     Declare all Obligations, whether evidenced by
this Agreement, by any of the other Loan Documents, or otherwise, immediately
due and payable (provided that upon the occurrence of an Event of Default
described in Section 8.5 all Obligations shall become immediately due and
payable without any action by Bank);

                          (b)     Cease advancing money or extending credit to
or for the benefit of Borrower under this Agreement or under any other
agreement between Borrower and Bank;

                          (c)     Settle or adjust disputes and claims directly
with account debtors for amounts, upon terms and in whatever order that Bank
reasonably considers advisable;

                          (d)     Without notice to or demand upon Borrower,
make such payments and do such acts as Bank considers necessary or reasonable
to protect its security interest in the Collateral.  Borrower agrees to
assemble the Collateral if Bank so requires, and to make the Collateral
available to Bank as Bank may designate.  Borrower authorizes Bank to enter the
premises where the Collateral is located, to take and maintain possession of
the Collateral, or any part of it, and to pay, purchase, contest, or compromise
any encumbrance, charge, or lien which in Bank's determination appears to be
prior or superior to its security interest and to pay all expenses incurred in
connection therewith.  With respect to any of Borrower's owned premises,
Borrower hereby grants Bank a license to enter into possession of such premises
and to occupy the same, without charge, in order to exercise any of Bank's
rights or remedies provided herein, at law, in equity, or otherwise;

                          (e)     Without notice to Borrower set off and apply
to the Obligations any and all (i) balances and deposits of Borrower held by
Bank, or (ii) indebtedness at any time owing to or for the credit or the
account of Borrower held by Bank;

                          (f)     Ship, reclaim, recover, store, finish,
maintain, repair, prepare for sale, advertise for sale, and sell (in the manner
provided for herein) the Collateral.  Bank is hereby granted a license or other
right, solely pursuant to the provisions of this Section 9.1, to use, without
charge, Borrower's labels, patents, copyrights, rights of use of any name,
trade secrets, trade names, trademarks, service marks, and advertising matter,
or any property of a similar nature, as it pertains to the Collateral, in
completing production of, advertising for sale, and selling any Collateral and,
in connection with Bank's exercise of its rights under this Section 9.1,
Borrower's rights under all licenses and all franchise agreements shall inure
to Bank's benefit;





                                       16
   20
                          (g)     Sell the Collateral at either a public or
private sale, or both, by way of one or more contracts or transactions, for
cash or on terms, in such manner and at such places (including Borrower's
premises) as Bank determines is commercially reasonable;

                          (h)     Bank may credit bid and purchase at any
public sale; and

                          (i)     Any deficiency that exists after disposition
of the Collateral as provided above will be paid immediately by Borrower.

                 9.2      Power of Attorney.  Effective only upon the
occurrence and during the continuance of an Event of Default, Borrower hereby
irrevocably appoints Bank (and any of Bank's designated officers, or employees)
as Borrower's true and lawful attorney to: (a) send requests for verification
of Accounts or notify account debtors of Bank's security interest in the
Accounts; (b) endorse Borrower's name on any checks or other forms of payment
or security that may come into Bank's possession; (c) sign Borrower's name on
any invoice or bill of lading relating to any Account, drafts against account
debtors, schedules and assignments of Accounts, verifications of Accounts, and
notices to account debtors; (d) make, settle, and adjust all claims under and
decisions with respect to Borrower's policies of insurance; and (e) settle and
adjust disputes and claims respecting the accounts directly with account
debtors, for amounts and upon terms which Bank determines to be reasonable;
provided Bank may exercise such power of attorney to sign the name of Borrower
on any of the documents described in Section 4.2 regardless of whether an Event
of Default has occurred.  The appointment of Bank as Borrower's attorney in
fact, and each and every one of Bank's rights and powers, being coupled with an
interest, is irrevocable until all of the Obligations have been fully repaid
and Bank's obligation to provide Advances hereunder is terminated.

                 9.3      Accounts Collection.  Upon the occurrence and during
the continuation of an Event of Default, Bank may notify any Person owing funds
to Borrower of Bank's security interest in such funds.  Borrower shall collect
all amounts owing to Borrower for Bank, receive in trust all payments as Bank's
trustee, and immediately deliver such payments to Bank in their original form
as received from the account debtor, with proper endorsements for deposit.

                 9.4      Bank Expenses.  If Borrower fails to pay any amounts
or furnish any required proof of payment due to third persons or entities, as
required under the terms of this Agreement, then Bank may do any or all of the
following: (a) make payment of the same or any part thereof; or (b) obtain and
maintain insurance policies of the type discussed in Section 6.6 of this
Agreement, and take any action with respect to such policies as Bank deems
prudent.  Any amounts so paid or deposited by Bank shall constitute Bank
Expenses, shall be immediately due and payable, and shall bear interest at the
then applicable rate hereinabove provided, and shall be secured by the
Collateral.  Any payments made by Bank shall not constitute an agreement by
Bank to make similar payments in the future or a waiver by Bank of any Event of
Default under this Agreement.

                 9.5      Bank's Liability for Collateral.  So long as Bank
complies with its obligations under Section 9207 of the Code, Bank shall not in
any way or manner be liable or responsible for: (a) the safekeeping of the
Collateral; (b) any loss or damage thereto occurring or arising in any manner
or fashion from any cause; (c) any diminution in the value thereof; or (d) any
act or default of any carrier, warehouseman, bailee, forwarding agency, or
other person whomsoever.  Subject to the foregoing, all risk of loss, damage or
destruction of the Collateral shall be borne by Borrower.

                 9.6      Remedies Cumulative.  Bank's rights and remedies
under this Agreement, the Loan Documents, and all other agreements shall be
cumulative.  Bank shall have all other rights and remedies not inconsistent
herewith as provided under the Code, by law, or in equity.  No exercise by Bank
of one right or remedy shall be deemed an election, and no waiver by Bank of
any Event of Default on Borrower's part shall be deemed a continuing waiver.
No delay by Bank shall constitute a





                                       17
   21
waiver, election, or acquiescence by it.  No waiver by Bank shall be effective
unless made in a written document signed on behalf of Bank

                 9.7      Demand; Protest.  Borrower waives demand, protest,
notice of protest, notice of dishonor, notice of payment and nonpayment, notice
of any default, nonpayment at maturity, release, compromise, settlement,
extension, or renewal of accounts, documents, instruments, chattel paper, and
guarantees at any time held by Bank on which Borrower may in any way be liable.

         10.     NOTICES

                 Unless otherwise provided in this Agreement, all notices or
demands by any party relating to this Agreement or any other agreement entered
into in connection herewith shall be in writing and (except for financial
statements and other informational documents which may be sent by first-class
mail, postage prepaid) shall be personally delivered or sent by a recognized
overnight delivery service, certified mail, postage prepaid, return receipt
requested, or by telefacsimile to Borrower or to Bank, as the case may be, at
its addresses set forth below:

         If to Borrower:          Calypte Biomedical Corporation 
                                  1440 Fourth Street 
                                  Berkeley, CA 94710
                                  Attn:    Mr. Jack Davis
                                  FAX:     (510) 526-5381

         If to Bank:              Silicon Valley Bank 
                                  3003 Tasman Drive 
                                  Santa Clara, CA 95054
                                  Attn:    Ms. Mitzi Lazich
                                  FAX:     (408) 727-8728

         The parties hereto may change the address at which they are to receive
notices hereunder, by notice in writing in the foregoing manner given to the
other.

          11.    CHOICE OF LAW AND VENUE; JURY TRIAL WAIVER

                 This Agreement shall be governed by, and construed in
accordance with, the internal laws of the State of California, without regard
to principles of conflicts of law.  Each of Borrower and Bank hereby submits
to the exclusive jurisdiction of the state and Federal courts located in the
County of Santa Clara, State of California.  BORROWER AND BANK EACH HEREBY
WAIVE THEIR RESPECTIVE RIGHTS TO A JURY TRIAL OF ANY CLAIM OR CAUSE OF ACTION
BASED UPON OR ARISING OUT OF ANY OF THE LOAN DOCUMENTS OR ANY OF THE 
TRANSACTIONS CONTEMPLATED THEREIN, INCLUDING CONTRACT CLAIMS, TORT CLAIMS,
BREACH OF DUTY CLAIMS, AND ALL OTHER COMMON LAW OR STATUTORY CLAIMS.  EACH
PARTY RECOGNIZES AND AGREES THAT THE FOREGOING WAIVER CONSTITUTES A MATERIAL
INDUCEMENT FOR IT TO ENTER INTO THIS AGREEMENT.  EACH PARTY REPRESENTS AND
WARRANTS THAT IT HAS REVIEWED THIS WAIVER WITH ITS LEGAL COUNSEL AND THAT IT
KNOWINGLY AND VOLUNTARILY WAIVES ITS JURY TRIAL RIGHTS FOLLOWING CONSULTATION
WITH LEGAL COUNSEL.

          12.    GENERAL PROVISIONS

                 12.1     Successors and Assigns.

                          (a)     This Agreement shall bind and inure to the
benefit of the respective successors and permitted assigns of each of the
parties; provided, however, that neither this





                                       18
   22
Agreement nor any rights hereunder may be assigned by Borrower without Bank's
prior written consent, which consent may be granted or withheld in Bank's sole
discretion.  Bank shall have the right without the consent of or notice to
Borrower to sell, transfer, negotiate, or grant participations in all or any
part of, or any interest in Bank's obligations, rights and benefits hereunder.

                          (b)     Bank may sell, negotiate or grant
participations to other financial institutions in all or part of the
obligations of the Borrower outstanding under the Loan Agreements, without
notice to or the approval of Borrower; provided that any such sale, negotiation
or participation shall be in compliance with the applicable federal and state
securities laws and the other requirements of this Section 12.1.
Notwithstanding the sale, negotiation or grant of participations, Bank shall
remain solely responsible for the performance of its obligations under this
Agreement, Bank shall remain the holder of the Note for all purposes under this
Agreement and Borrower shall continue to deal solely and directly with Bank in
connection with this Agreement and the other Loan Documents.

                          (c)     The grant of a participation interest shall
be on such terms as the Bank determines are appropriate, provided only that (i)
the holder of such participation interest shall not have any of the rights of
Bank under this Agreement except, if the participation agreement so provides,
rights to demand the payment of costs of the type described in Section 2.7,
provided that the aggregate amount that the Borrower shall be required to pay
under Section 2.7 with respect to any ratable share of the Committed Line or
any Advance (including amounts paid to participants) shall not exceed the
amount that Borrower would have had to pay if no participation agreements had
been entered into, and (ii) the consent of the holder of such a participation
interest shall not be required for amendments or waivers of provisions of the
Loan Agreement other than those which (A) increase the amount of the Committed
Line, (B) extend the term of this Agreement, (C) decrease the rate of interest
or the amount of any fee or any other amount payable to Bank under this
Agreement, (D) reduce the principal amount payable under this Agreement, or (E)
extend the date fixed for the payment of principal or interest or any other
amount payable under this Agreement.

                          (d)     The Bank may assign, from time to time, all
or any portion of its pro rata share of the Committed Line and the Note to an
Affiliate of the Bank or, subject to the prior written approval of Borrower
(which approval will not be unreasonably withheld), to any other financial
institution; provided, that (i) the amount the Committed Line being assigned
pursuant to each such assignment shall in no event be less than One Million
Dollars ($1,000,000) and shall be an integral multiple of Two Hundred Fifty
Thousand Dollars ($250,000) and (ii) the parties to each such assignment shall
execute and deliver to Borrower an assignment agreement in a form reasonably
acceptable to each.  Upon such execution and delivery, from and after the
effective date specified in such assignment agreement (x) the assignee
thereunder shall be a party hereto and, to the extent that rights and
obligations hereunder have been assigned to it pursuant to such assignment
agreement, have the rights and obligations of a Bank hereunder and (y) Bank
shall, to the extent that rights and obligations hereunder have been assigned
by it pursuant to such assignment agreement, relinquish its rights and be
released from its obligations under this Agreement (other than pursuant to this
Section 12.1(d), and, in the case of an assignment agreement covering all or
the remaining portion of Bank's rights and obligations under this Agreement,
Bank shall cease to be a party hereto.  In the event of an assignment
hereunder, the parties agree to amend this Agreement to the extent necessary to
reflect the mechanical changes which are necessary to document such assignment
and which are standard for a multi-bank credit facility.  Each party shall bear
its own expenses (including without limitation attorneys' fees and costs) with
respect to such an amendment.

                 12.2     Indemnification.  Borrower shall defend, indemnify
and hold harmless Bank and its officers, employees, and agents against: (a) all
obligations, demands, claims, and liabilities claimed or asserted by any other
party in connection with the transactions contemplated by this Agreement; and
(b) all losses or Bank Expenses in any way suffered, incurred, or paid by Bank
as a result of or in any way arising out of, following, or consequential to
transactions between Bank and





                                       19
   23
Borrower whether under this Agreement, or otherwise (including without
limitation reasonable attorneys fees and expenses), except for losses caused by
Bank's gross negligence or willful misconduct.

                 12.3     Time of Essence.  Time is of the essence for the
performance of all obligations set forth in this Agreement.

                 12.4     Severability of Provisions.  Each provision of this
Agreement shall be severable from every other provision of this Agreement for
the purpose of determining the legal enforceability of any specific provision.

                 12.5     Amendments in Writing, Integration.  This Agreement
cannot be amended or terminated orally.  All prior agreements, understandings,
representations, warranties, and negotiations between the parties hereto with
respect to the subject matter of this Agreement, if any, are merged into this
Agreement and the Loan Documents.

                 12.6     Counterparts.  This Agreement may be executed in any
number of counterparts and by different parties on separate counterparts, each
of which, when executed and delivered, shall be deemed to be an original, and
all of which, when taken together, shall constitute but one and the same
Agreement.

                 12.7     Survival.  All covenants, representations and
warranties made in this Agreement shall continue in full force and effect so
long as any Obligations (excluding Obligations under Sections 2.6 and 12.2 to
the extent they remain inchoate at the time that outstanding payment
Obligations are paid in full) remain outstanding.  The obligations of Borrower
to indemnify Bank with respect to the expenses, damages, losses, costs and
liabilities described in Section 12.2 shall survive until all applicable
statute of limitations periods with respect to actions that may be brought
against Bank have run, provided that so long as the obligations set forth in
the first sentence of this Section 12.7 have been satisfied, and Bank has no
commitment to make any Advances or to make any other loans to Borrower, Bank
shall release all security interests granted hereunder and redeliver all
Collateral held by it in accordance with applicable law.

                 12.8     Confidentiality.  In handling any confidential
information Bank shall exercise the same degree of care that it exercises with
respect to its own proprietary information of the same types to maintain the
confidentiality of any non-public information thereby received or received
pursuant to this Agreement except that disclosure of such information may be
made (i) to the subsidiaries or affiliates of Bank in connection with their
present or prospective business relations with Borrower, (ii) to prospective
transferees or purchasers of any interest in the Loans, provided that they have
entered into a comparable confidentiality agreement in favor of Borrower and
have delivered a copy to Borrower, (iii) as required by law, regulations, rule
or order, subpoena, judicial order or similar order, (iv) as may be required in
connection with the examination, audit or similar investigation of Bank, and
(v) as Bank may deem appropriate in connection with the exercise of any
remedies under this Agreement.  Confidential information hereunder shall not
include information that either: (a) is in the public domain or in the
knowledge or possession of Bank when disclosed to Bank, or becomes part of the
public domain after disclosure to Bank through no fault of Bank; or (b) is
disclosed to the Bank by a third party, provided the Bank does not have actual
knowledge that such third party is prohibited from disclosing such information.
Notwithstanding any provision of this Agreement to the contrary, neither
Borrower nor any of its Subsidiaries will be required to disclose, permit the
inspection, examination, copying or making extracts of, or discussions of; any
document, information or other matter that (i) prior to the occurrence of an
Event of Default constitutes nonfinancial trade secrets, or (ii) in respect to
which disclosure to the Banks (or designated representative) is then prohibited
by (a) law, or (b) an agreement binding upon Borrower or any Subsidiary that
was not entered into by Borrower or such Subsidiary for the primary purpose of
concealing information from Banks.





                                       20
   24

         IN WITNESS WHEREOF, the parties hereto have caused this Agreement to
be executed as of the date first above written.



                                            CALYPTE BIOMEDICAL CORPORATION



                                            By:______________________________

                                            Title:______________________________


                                            SILICON VALLEY BANK

                                            By:______________________________

                                            Title:______________________________





                                       21
   25

                                   EXHIBIT A


         The Collateral shall consist of all right, title and interest of
Borrower in and to the following:

         (a)     All goods and equipment now owned or hereafter acquired,
including, without limitation, all machinery, fixtures, vehicles (including
motor vehicles and trailers), and any interest in any of the foregoing, and all
attachments, accessories, accessions, replacements, substitutions, additions,
and improvements to any of the foregoing, wherever located;

         (b)     All inventory, now owned or hereafter acquired, including,
without limitation, all merchandise, raw materials, parts, supplies, packing
and shipping materials, work in process and finished products including such
inventory as is temporarily out of Borrower's custody or possession or in
transit and including any returns upon any accounts or other proceeds,
including insurance proceeds, resulting from the sale or disposition of any of
the foregoing and any documents of title representing any of the above, and
Borrower's Books relating to any of the foregoing;

         (c)     All contract rights and general intangibles now owned or
hereafter acquired, including, without limitation, goodwill, trademarks,
service marks, trade styles, trade names, patents, patent applications, leases,
license agreements, franchise agreements, blueprints, drawings, purchase
orders, customer lists, route lists, infringements, claims, computer programs,
computer discs, computer tapes, literature, reports, catalogs, design rights,
income tax refunds, payments of insurance and rights to payment of any kind;

         (d)     All now existing and hereafter arising accounts, contract
rights, royalties, license rights and all other forms of obligations owing to
Borrower arising out of the sale or lease of goods, the licensing of technology
or the rendering of services by Borrower, whether or not earned by performance,
and any and all credit insurance, guaranties, and other security therefor, as
well as all merchandise returned to or reclaimed by Borrower and Borrower's
Books relating to any of the foregoing;

         (e)     All documents, cash, deposit accounts, securities (other than
securities of foreign Subsidiaries), letters of credit, certificates of
deposit, instruments and chattel paper now owned or hereafter acquired and
Borrower's Books relating to the foregoing;

         (f)     All copyright rights, copyright applications, copyright
registrations and like protections in each work of authorship and derivative
work thereof, whether published or unpublished, now owned or hereafter
acquired; all trade secret rights, including all rights to unpatented.
inventions, know-how, operating manuals, license rights and agreements and
confidential information, now owned or hereafter acquired; all claims for
damages by way of any past, present and future infringement of any of the
foregoing; and

         (g)     Any and all claims, rights and interests in any of the above
and all substitutions for, additions and accessions to and proceeds thereof.





                                       22
   26
                                   EXHIBIT B
                             COMPLIANCE CERTIFICATE



TO:              SILICON VALLEY BANK

FROM:            CALYPTE BIOMEDICAL CORPORATION

         The undersigned authorized officer of Calypte Biomedical Corporation
hereby certifies that in accordance with the terms and conditions of the Loan
and Security Agreement between Borrower and Bank (the "Agreement"), (i)
Borrower is in complete compliance for the period ending _____________ with 
all required covenants except as noted below and (ii) all representations and
warranties of Borrower stated in the Agreement are true and correct in all
material respects as of the date hereof.  Attached herewith are the required
documents supporting the above certification.  The Officer further certifies
that these are prepared in accordance with Generally Accepted Accounting
Principles (GAAP) and are consistently applied from one period to the next
except as explained in an accompanying letter or footnotes.

    PLEASE INDICATE COMPLIANCE STATUS BY CIRCLING YES/NO UNDER "COMPLIES" COLUMN



REPORTING COVENANT                                        REQUIRED                                          COMPLIES
                                                                                                            

Monthly financial statements                              Monthly within 30 days                             Yes     No
Annual (CPA Audited)                                      FYE within 90 days                                 Yes     No




FINANCIAL COVENANT                                        REQUIRED                  ACTUAL                   COMPLIES

                                                                                                      
Maintain on a Monthly Basis:
  Minimum Cash and Cash Equivalents                       $700,000                $                       Yes     No
                                                                                   ----------                       







                                                   
COMMENTS REGARDING EXCEPTIONS: See Attached.          BANK USE ONLY

                                                      Received by:_________________
Sincerely,                                                        AUTHORIZED SIGNER

______________________________                        Date:________________________
SIGNATURE
                                                      Verified:____________________
                                                                AUTHORIZED SIGNER
______________________________                        Date:________________________
TITLE

______________________________                 Compliance Status:     Yes    No
DATE




                                       23
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                       SCHEDULE OF PERMITTED INDEBTEDNESS























                                       24
   28
                     DISBURSEMENT REQUEST AND AUTHORIZATION


Borrower: Calypte Biomedical Corporation             Bank: Silicon Valley Bank
===============================================================================


LOAN TYPE.  This is a Variable Rate Bridge Loan of a principal amount up to
$2,000,000

PRIMARY PURPOSE OF LOAN.  The primary purpose of this loan is for business.

SPECIFIC PURPOSE.  The specific purpose of this loan is: Short Term Working
Capital.

DISBURSEMENT INSTRUCTIONS.  Borrower understands that no loan proceeds will 
be disbursed until all of Bank's conditions for making the loan have been
satisfied.  Please disburse the loan proceeds as follows:



                                                                                                          Bridge Loan
                                                                                                        
              Amount paid to Borrower directly:                                                            $2,000,000
              Undisbursed Funds                                                                                    $0

              Principal                                                                                    $2,000,000


CHARGES PAID IN CASH.  Borrower has paid or will pay in cash as agreed the
following charges:


                                                                                                          
              Prepaid Finance Charges Paid in Cash:                                                          $          
                                                                                                              ----------
                      $10,000    Loan Fee

              Other Charges Paid in Cash:                                                                    $__________
                      $          Outside Counsel Fees and Expenses (Estimate)
                       ----------                                            

              Total Charges Paid in Cash                                                                     $__________   
                                                                                                              ----------


AUTOMATIC PAYMENTS.  Borrower hereby authorizes Bank automatically to deduct
from Borrower's account numbered ______ the amount of any loan payment.  If 
the funds in the account are insufficient to cover any payment, Bank shall not 
be obligated to advance funds to cover the payment.

FINANCIAL CONDITION.  BY SIGNING THIS AUTHORIZATION, BORROWER REPRESENTS AND
WARRANTS TO BANK THAT THE INFORMATION PROVIDED ABOVE IS TRUE AND CORRECT AND
THAT THERE HAS BEEN NO ADVERSE CHANGE IN BORROWER'S FINANCIAL CONDITION AS
DISCLOSED IN BORROWER'S MOST RECENT FINANCIAL STATEMENT TO BANK.  THIS
AUTHORIZATION IS DATED AS OF DECEMBER _______1995.

BORROWER:

CALYPTE BIOMEDICAL CORPORATION


______________________________
Authorized Officer

================================================================================






   29
                         AGREEMENT TO PROVIDE INSURANCE


GRANTOR:   Calypte Biomedical Corporation     BANK:        Silicon Valley Bank

================================================================================




         INSURANCE REQUIREMENTS.  Calypte Biomedical Corporation ("Grantor")
understands that insurance coverage is required in connection with the
extending of a loan or the providing of other financial accommodations to
Grantor by Bank.  These requirements are set forth in the Loan Documents.  The
following minimum insurance coverages must be provided on the following
described collateral (the "Collateral"):

         Collateral:      All Inventory, Equipment and Fixtures.
         Type:            All risks, including fire, theft and liability.
         Amount:          Full insurable value.
         Basis:           Replacement value.
         Endorsements:    Loss payable clause to Bank with stipulation that
                          coverage will not be cancelled or diminished without
                          a minimum of twenty (20) days' prior written notice
                          to Bank.

         INSURANCE COMPANY.  Grantor may obtain insurance from any insurance
company Grantor may choose that is reasonably acceptable to Bank.  Grantor
understands that credit may not be denied solely because insurance was not
purchased through Bank.

         FAILURE TO PROVIDE INSURANCE.  Grantor agrees to deliver to Bank, on
or before closing, evidence of the required insurance as provided above, with
an effective date of December 8, 1995, or earlier.  Grantor acknowledges and
agrees that if Grantor fails to provide any required insurance or fails to
continue such insurance in force, Bank may do so at Grantor's expense as
provided in the Loan and Security Agreement.  The cost of such insurance, at
the option of Bank, shall be payable on demand or shall be added to the
indebtedness as provided in the security document.  GRANTOR ACKNOWLEDGES THAT
IF BANK SO PURCHASES ANY SUCH INSURANCE, THE INSURANCE WILL PROVIDE LIMITED
PROTECTION AGAINST PHYSICAL DAMAGE TO THE COLLATERAL, UP TO THE BALANCE OF THE
LOAN; HOWEVER, GRANTOR'S EQUITY IN THE COLLATERAL MAY NOT BE INSURED.  IN
ADDITION, THE INSURANCE MAY NOT PROVIDE ANY PUBLIC LIABILITY OR PROPERTY DAMAGE
INDEMNIFICATION AND MAY NOT MEET THE REQUIREMENTS OF ANY FINANCIAL
RESPONSIBILITY LAWS.

         AUTHORIZATION.  For purposes of insurance coverage on the Collateral,
Grantor authorizes Bank to provide to any person (including any insurance agent
or company) all information Bank deems appropriate, whether regarding the
Collateral, the loan or other financial accommodations, or both.

         GRANTOR ACKNOWLEDGES HAVING READ ALL THE PROVISIONS OF THIS AGREEMENT
TO PROVIDE INSURANCE AND AGREES TO ITS TERMS.  THIS AGREEMENT IS DATED DECEMBER
8,1995.

GRANTOR:

______________________________



X______________________________
Authorized Officer



                               FOR BANK USE ONLY
                             INSURANCE VERIFICATION

DATE:______________________________
PHONE:_____________________________

AGENT'S NAME:__________________________________________________________________
INSURANCE COMPANY:_____________________________________________________________
POLICY NUMBER:_________________________________________________________________
EFFECTIVE DATES:_______________________________________________________________
COMMENTS:______________________________________________________________________






   30
                        CORPORATE RESOLUTIONS TO BORROW

================================================================================

BORROWER:         CALYPTE BIOMEDICAL CORPORATION

================================================================================


         I, the undersigned Secretary or Assistant Secretary of Calypte
Biomedical Corporation (the "Corporation"), HEREBY CERTIFY that the Corporation
is organized and existing under and by virtue of the laws of the State of
California.

         I FURTHER CERTIFY that at a meeting of the Directors of the
Corporation (or by other duly authorized corporate action in lieu of a
meeting), duly called and held, at which a quorum was present and voting, the
following resolutions were adopted.

         BE IT RESOLVED, that ANY ONE (1) of the following named officers,
employees, or agents of this Corporation, whose actual signatures are shown
below:



         NAMES                               POSITIONS                                ACTUAL SIGNATURES
      ---------                              ---------                                -----------------
                                                                                
JACK DAVIS                                  PRESIDENT & CEO  
- --------------------                        --------------------                      --------------------
JOHN DI PIETRO                              CFO & VP FINANCE & SECRETARY    
- --------------------                        --------------------                      --------------------

- --------------------                        --------------------                      --------------------

- --------------------                        --------------------                      --------------------

- --------------------                        --------------------                      --------------------



acting for and on behalf of this Corporation and as its act and deed be, and
they hereby are, authorized and empowered:

         BORROW MONEY.  To borrow from time to time from Silicon Valley Bank
("Bank"), on such terms as may be agreed upon between the officers, employees,
or agents and Bank, such sum or sums of money as in their judgment should be
borrowed, without limitation, including such sums as are specified in that
certain Loan and Security Agreement dated as of December 8, 1995 (the "Loan
Agreement").

         EXECUTE NOTES.  To execute and deliver to Bank the Loan Agreement and
any promissory note or notes of the Corporation, on Lender's forms, at such
rates of interest and on such terms as may be agreed upon, evidencing the sums
of money so borrowed or any indebtedness of the Corporation to Bank, and also
to execute and deliver to Lender one or more renewals, extensions,
modifications, refinancings, consolidations, or substitutions for one or more
of the notes, or any portion of the notes.

         GRANT SECURITY.  To grant a security interest to Bank in the
Collateral described in the Loan Agreement, which security interest shall secure
all of the Corporation's Obligations, as described in the Loan Agreement.

         NEGOTIATE ITEMS.  To draw, endorse, and discount with Bank all drafts,
trade acceptances, promissory notes, or other evidences of indebtedness payable
to or belonging to the Corporation or in which the Corporation may have an
interest, and either to receive cash for the same or to cause such proceeds to
be credited to the account of the Corporation with Bank, or to cause such other
disposition of the proceeds derived therefrom as they may deem advisable.





                                       1
                                       
   31
         LETTERS OF CREDIT.  To execute letters of credit applications and
other related documents pertaining to Bank's issuance of letters of credit.

         FURTHER ACTS.  In the case of lines of credit, to designate additional
or alternate individuals as being authorized to request advances thereunder,
and in all cases, to do and perform such other acts and things, to pay any and
all fees and costs, and to execute and deliver such other documents and
agreements as they may in their discretion deem reasonably necessary or proper
in order to carry into effect the provisions of these Resolutions.

         BE IT FURTHER RESOLVED, that any and all acts authorized pursuant to
these resolutions and performed prior to the passage of these resolutions are
hereby ratified and approved, that these Resolutions shall remain in full force
and effect and Bank may rely on these Resolutions until written notice of their
revocation shall have been delivered to and received by Bank.  Any such notice
shall not affect any of the Corporation's agreements or commitments in effect
at the time notice is given.

         I FURTHER CERTIFY that the officers, employees, and agents named above
are duly elected, appointed, or employed by or for the Corporation, as the case
may be, and occupy the positions set forth opposite their respective names;
that the foregoing Resolutions now stand of record on the books of the
Corporation; and that the Resolutions are in full force and effect and have not
been modified or revoked in any manner whatsoever.

         IN WITNESS WHEREOF, I have hereunto set my hand on December __, 1995
and attest that the signatures set opposite the names listed above are their
genuine signatures.


                                                   CERTIFIED TO AND ATTESTED BY:


                                                 X______________________________



================================================================================






                                       2
   32
                         INVOICE FOR FEES AND EXPENSES

                                BORROWER:  CALYPTE BIOMEDICAL CORPORATION

                                LOAN OFFICER:      Mitzi Lazich

                                DATE:      December 7, 1995


                                                                                             
                                                      Loan Fees:                                 $20,000.00
                                                      Credit Reports:                                 35.00
                                                      UCC Search:                                    150.00
                                                      UCC Filing Fee:                                 20.00
                                                                                                 ----------
                                                      Total Fees:                                $20,205.00*
                                                      Less Payment
                                                      Received:                                   10,000.00
                                                                                                 ----------
                                                      TOTAL FEES DUE:                            $10,205.00



         *This is an estimate only, the actual expenses may vary. 
PLEASE INDICATE THE METHOD OF PAYMENT:

                 ( )      A check for the total amount is attached

                 ( )      Debit DDA #____________ for the total amount

                 ( )      Loan proceeds


CALYPTE BIOMEDICAL CORPORATION


______________________________                            ____________________
Authorized Signer                                         Date


SILICON VALLEY BANK


______________________________                            ____________________
Julie Schneider                                           Date





   33
                             STATE OF CALIFORNIA
           UNIFORM COMMERCIAL CODE--FINANCING STATEMENT--FORM UCC-1

 This financing Statement is presented for filing and will remain effective,
       with certain exceptions, for five years from the date of filing,
     pursuant to Section 9403 of the California Uniform Commercial Code.


                                                                                                       
- ----------------------------------------------------------------------------------------------------------------------------------
1. DEBTOR                                                                               1A. SOCIAL SECURITY OR FEDERAL TAX NO.
                CALYPTE BIOMEDICAL CORPORATION
- ----------------------------------------------------------------------------------------------------------------------------------
1B. MAILING ADDRESS                                                           1C. CITY, STATE                   1D. ZIP CODE
                1440 FOURTH STREET                                                BERKELEY, CA                      94710
- ----------------------------------------------------------------------------------------------------------------------------------
2. ADDITIONAL DEBTOR                                                                    2A. SOCIAL SECURITY OR FEDERAL TAX NO.

- ----------------------------------------------------------------------------------------------------------------------------------
2b. MAILING ADDRESS                                                           2C. CITY, STATE                   2D. ZIP CODE

- ----------------------------------------------------------------------------------------------------------------------------------
3. DEBTOR'S TRADE NAMES OR STYLES                                                       3A. FEDERAL TAX NUMBER

- ----------------------------------------------------------------------------------------------------------------------------------
4. SECURED PARTY                                                                        4A. FEDERAL TAX NO.
                SILICON VALLEY BANK
                3003 TASMAN DRIVE                                                           94-2875288
                SANTA CLARA, CA 95054
- ----------------------------------------------------------------------------------------------------------------------------------
5. ASSIGNEE OF SECURED PARTY                                                            5A. FEDERAL TAX NO.


- ----------------------------------------------------------------------------------------------------------------------------------
6. This FINANCING STATEMENT covers the following type of property:

        SEE EXHIBIT "A" ATTACHED HERETO AND MADE A PART HEREOF BY THIS REFERENCE.



- ----------------------------------------------------------------------------------------------------------------------------------
7A. [X]  PRODUCTS OF COLLATERAL ARE ALSO COVERED    7B. DEBTOR(S) SIGNATURE NOT REQUIRED IN ACCORDANCE WITH INSTRUCTION 5(a) ITEM:
                                                        [ ] (1)         [ ] (2)         [ ] (3)         [ ] (4)
- ----------------------------------------------------------------------------------------------------------------------------------
8. [ ]  DEBTOR IS A "TRANSMITTING UTILITY" IN ACCORDANCE WITH UCC SECTION 9105 (1) (o)
- ----------------------------------------------------------------------------------------------------------------------------------
9.                                      DATE:  12-07-1995       C       10. THIS SPACE FOR USE OF FILING OFFICER
       [SIG]                                                    O       (DATE, TIME, FILE NUMBER AND FILING OFFICER)
                                                                D
SIGNATURE(S) OF DEBTOR(S)                                       E
- ---------------------------------------------------------------------
CALYPTE BIOMEDICAL CORPORATION                                  1

- -------------------------------------------------------------   2

                                                                3

SIGNATURE(S) OF SECURED PARTY(IES)                              4
- -------------------------------------------------------------
SILICON VALLEY BANK                                             5

=============================================================   6
11. Return copy to:
                                                                7
        /                                       /
                SILICON VALLEY BANK                             8
                DOCUMENTATION/NC 661
                3003 TASMAN DRIVE                               9
                SANTA CLARA, CA 95054
        /                                       /               0
=============================================================

                        FORM UCC-1

==================================================================================================================================

   34
                             STATE OF CALIFORNIA
           UNIFORM COMMERCIAL CODE--FINANCING STATEMENT--FORM UCC-1

 This financing Statement is presented for filing and will remain effective,
       with certain exceptions, for five years from the date of filing,
     pursuant to Section 9403 of the California Uniform Commercial Code.


                                                                                                       
- ----------------------------------------------------------------------------------------------------------------------------------
1. DEBTOR                                                                               1A. SOCIAL SECURITY OR FEDERAL TAX NO.
                CALYPTE BIOMEDICAL CORPORATION
- ----------------------------------------------------------------------------------------------------------------------------------
1B. MAILING ADDRESS                                                           1C. CITY, STATE                   1D. ZIP CODE
                1440 FOURTH STREET                                                BERKELEY, CA                      94710
- ----------------------------------------------------------------------------------------------------------------------------------
2. ADDITIONAL DEBTOR                                                                    2A. SOCIAL SECURITY OR FEDERAL TAX NO.

- ----------------------------------------------------------------------------------------------------------------------------------
2b. MAILING ADDRESS                                                           2C. CITY, STATE                   2D. ZIP CODE

- ----------------------------------------------------------------------------------------------------------------------------------
3. DEBTOR'S TRADE NAMES OR STYLES                                                       3A. FEDERAL TAX NUMBER

- ----------------------------------------------------------------------------------------------------------------------------------
4. SECURED PARTY                                                                        4A. FEDERAL TAX NO.
                SILICON VALLEY BANK
                3003 TASMAN DRIVE                                                           94-2875288
                SANTA CLARA, CA 95054
- ----------------------------------------------------------------------------------------------------------------------------------
5. ASSIGNEE OF SECURED PARTY                                                            5A. FEDERAL TAX NO.


- ----------------------------------------------------------------------------------------------------------------------------------
6. This FINANCING STATEMENT covers the following type of property:

        SEE EXHIBIT "A" ATTACHED HERETO AND MADE A PART HEREOF BY THIS REFERENCE.



- ----------------------------------------------------------------------------------------------------------------------------------
7A. [X]  PRODUCTS OF COLLATERAL ARE ALSO COVERED    7B. DEBTOR(S) SIGNATURE NOT REQUIRED IN ACCORDANCE WITH INSTRUCTION 5(a) ITEM:
                                                        [ ] (1)         [ ] (2)         [ ] (3)         [ ] (4)
- ----------------------------------------------------------------------------------------------------------------------------------
8. [ ]  DEBTOR IS A "TRANSMITTING UTILITY" IN ACCORDANCE WITH UCC SECTION 9105 (1) (o)
- ----------------------------------------------------------------------------------------------------------------------------------
9.                                      DATE:  12-07-1995       C       10. THIS SPACE FOR USE OF FILING OFFICER
       [SIG]                                                    O       (DATE, TIME, FILE NUMBER AND FILING OFFICER)
                                                                D
SIGNATURE(S) OF DEBTOR(S)                                       E
- ---------------------------------------------------------------------
CALYPTE BIOMEDICAL CORPORATION                                  1

- -------------------------------------------------------------   2

                                                                3

SIGNATURE(S) OF SECURED PARTY(IES)                              4
- -------------------------------------------------------------
SILICON VALLEY BANK                                             5

=============================================================   6
11. Return copy to:
                                                                7
        /                                       /
                SILICON VALLEY BANK                             8
                DOCUMENTATION/NC 661
                3003 TASMAN DRIVE                               9
                SANTA CLARA, CA 95054
        /                                       /               0
=============================================================

                        FORM UCC-1

==================================================================================================================================

   35
                             STATE OF CALIFORNIA
           UNIFORM COMMERCIAL CODE--FINANCING STATEMENT--FORM UCC-1

 This financing Statement is presented for filing and will remain effective,
       with certain exceptions, for five years from the date of filing,
     pursuant to Section 9403 of the California Uniform Commercial Code.


                                                                                                       
- ----------------------------------------------------------------------------------------------------------------------------------
1. DEBTOR                                                                               1A. SOCIAL SECURITY OR FEDERAL TAX NO.
                CALYPTE BIOMEDICAL CORPORATION
- ----------------------------------------------------------------------------------------------------------------------------------
1B. MAILING ADDRESS                                                           1C. CITY, STATE                   1D. ZIP CODE
                1440 FOURTH STREET                                                BERKELEY, CA                      94710
- ----------------------------------------------------------------------------------------------------------------------------------
2. ADDITIONAL DEBTOR                                                                    2A. SOCIAL SECURITY OR FEDERAL TAX NO.

- ----------------------------------------------------------------------------------------------------------------------------------
2b. MAILING ADDRESS                                                           2C. CITY, STATE                   2D. ZIP CODE

- ----------------------------------------------------------------------------------------------------------------------------------
3. DEBTOR'S TRADE NAMES OR STYLES                                                       3A. FEDERAL TAX NUMBER

- ----------------------------------------------------------------------------------------------------------------------------------
4. SECURED PARTY                                                                        4A. FEDERAL TAX NO.
                SILICON VALLEY BANK
                3003 TASMAN DRIVE                                                           94-2875288
                SANTA CLARA, CA 95054
- ----------------------------------------------------------------------------------------------------------------------------------
5. ASSIGNEE OF SECURED PARTY                                                            5A. FEDERAL TAX NO.


- ----------------------------------------------------------------------------------------------------------------------------------
6. This FINANCING STATEMENT covers the following type of property:

        SEE EXHIBIT "A" ATTACHED HERETO AND MADE A PART HEREOF BY THIS REFERENCE.



- ----------------------------------------------------------------------------------------------------------------------------------
7A. [X]  PRODUCTS OF COLLATERAL ARE ALSO COVERED    7B. DEBTOR(S) SIGNATURE NOT REQUIRED IN ACCORDANCE WITH INSTRUCTION 5(a) ITEM:
                                                        [ ] (1)         [ ] (2)         [ ] (3)         [ ] (4)
- ----------------------------------------------------------------------------------------------------------------------------------
8. [ ]  DEBTOR IS A "TRANSMITTING UTILITY" IN ACCORDANCE WITH UCC SECTION 9105 (1) (o)
- ----------------------------------------------------------------------------------------------------------------------------------
9.                                      DATE:  12-07-1995       C       10. THIS SPACE FOR USE OF FILING OFFICER
       [SIG]                                                    O       (DATE, TIME, FILE NUMBER AND FILING OFFICER)
                                                                D
SIGNATURE(S) OF DEBTOR(S)                                       E
- ---------------------------------------------------------------------
CALYPTE BIOMEDICAL CORPORATION                                  1

- -------------------------------------------------------------   2

                                                                3

SIGNATURE(S) OF SECURED PARTY(IES)                              4
- -------------------------------------------------------------
SILICON VALLEY BANK                                             5

=============================================================   6
11. Return copy to:
                                                                7
        /                                       /
                SILICON VALLEY BANK                             8
                DOCUMENTATION/NC 661
                3003 TASMAN DRIVE                               9
                SANTA CLARA, CA 95054
        /                                       /               0
=============================================================

                        FORM UCC-1

==================================================================================================================================


   36
                             STATE OF CALIFORNIA
           UNIFORM COMMERCIAL CODE--FINANCING STATEMENT--FORM UCC-1

 This financing Statement is presented for filing and will remain effective,
       with certain exceptions, for five years from the date of filing,
     pursuant to Section 9403 of the California Uniform Commercial Code.


                                                                                                       
- ----------------------------------------------------------------------------------------------------------------------------------
1. DEBTOR                                                                               1A. SOCIAL SECURITY OR FEDERAL TAX NO.
                CALYPTE BIOMEDICAL CORPORATION
- ----------------------------------------------------------------------------------------------------------------------------------
1B. MAILING ADDRESS                                                           1C. CITY, STATE                   1D. ZIP CODE
                1440 FOURTH STREET                                                BERKELEY, CA                      94710
- ----------------------------------------------------------------------------------------------------------------------------------
2. ADDITIONAL DEBTOR                                                                    2A. SOCIAL SECURITY OR FEDERAL TAX NO.

- ----------------------------------------------------------------------------------------------------------------------------------
2b. MAILING ADDRESS                                                           2C. CITY, STATE                   2D. ZIP CODE

- ----------------------------------------------------------------------------------------------------------------------------------
3. DEBTOR'S TRADE NAMES OR STYLES                                                       3A. FEDERAL TAX NUMBER

- ----------------------------------------------------------------------------------------------------------------------------------
4. SECURED PARTY                                                                        4A. FEDERAL TAX NO.
                SILICON VALLEY BANK
                3003 TASMAN DRIVE                                                           94-2875288
                SANTA CLARA, CA 95054
- ----------------------------------------------------------------------------------------------------------------------------------
5. ASSIGNEE OF SECURED PARTY                                                            5A. FEDERAL TAX NO.


- ----------------------------------------------------------------------------------------------------------------------------------
6. This FINANCING STATEMENT covers the following type of property:

        SEE EXHIBIT "A" ATTACHED HERETO AND MADE A PART HEREOF BY THIS REFERENCE.



- ----------------------------------------------------------------------------------------------------------------------------------
7A. [X]  PRODUCTS OF COLLATERAL ARE ALSO COVERED    7B. DEBTOR(S) SIGNATURE NOT REQUIRED IN ACCORDANCE WITH INSTRUCTION 5(a) ITEM:
                                                        [ ] (1)         [ ] (2)         [ ] (3)         [ ] (4)
- ----------------------------------------------------------------------------------------------------------------------------------
8. [ ]  DEBTOR IS A "TRANSMITTING UTILITY" IN ACCORDANCE WITH UCC SECTION 9105 (1) (o)
- ----------------------------------------------------------------------------------------------------------------------------------
9.                                      DATE:  12-07-1995       C       10. THIS SPACE FOR USE OF FILING OFFICER
       [SIG]                                                    O       (DATE, TIME, FILE NUMBER AND FILING OFFICER)
                                                                D
SIGNATURE(S) OF DEBTOR(S)                                       E
- ---------------------------------------------------------------------
CALYPTE BIOMEDICAL CORPORATION                                  1

- -------------------------------------------------------------   2

                                                                3

SIGNATURE(S) OF SECURED PARTY(IES)                              4
- -------------------------------------------------------------
SILICON VALLEY BANK                                             5

=============================================================   6
11. Return copy to:
                                                                7
        /                                       /
                SILICON VALLEY BANK                             8
                DOCUMENTATION/NC 661
                3003 TASMAN DRIVE                               9
                SANTA CLARA, CA 95054
        /                                       /               0
=============================================================

                        FORM UCC-1

==================================================================================================================================


   37
                              SILICON VALLEY BANK
                            FUNDS TRANSFER AGREEMENT
                      SECURITY PROCEDURE SERVICE ADDENDUM

         The following contains a description of the security procedures
offered by Silicon Valley Bank ("Bank") to authenticate a Client's Payment
Order instructions.  Except as otherwise specified, these security procedures
are not designed to detect, and Bank has no obligation to detect, Client error
in the transmission or content of instructions for the Payment Order.

TELEPHONE-INITIATED PAYMENT ORDERS
DOMESTIC AND INTERNATIONAL

REPETITIVE PAYMENT ORDERS- PRIMARY SECURITY PROCEDURE

         All repetitive Payment Orders, including repetitive Payment Orders to
beneficiaries located outside the United States, may be telephone-initiated.
Bank's Primary Security Procedure is to require Client to provide the signature
of an Authorized Representative (as listed in the Authorized Representative
Addendum) on Client's Repetitive Transfer Request form other standard form
used by Bank to document repetitive transfer services.  Upon receiving the
signed Repetitive Transfer Request, Bank will verify the signature of the
Authorized Representative against the signature specimen on file with Bank and
perform a Call-Back to a different Authorized Representative to verify the
repetitive transfer information.  In addition, Bank will provide Client with a
Repetitive Payment Identification Code to be used when Client's Authorized
Representative initiates a Payment Order instruction by telephone.  Bank will
perform a Call-Back on every repetitive Payment Order to a different Authorized
Representative when a Repetitive Payment Order is initiated.  Client shall
maintain the highest level of security of the code utilized in connection with
the Security Procedures.  Client shall promptly notify Bank of any compromise
of security or unauthorized disclosure or use and shall promptly thereafter
confirm such information in writing to Bank.  Client will be responsible for
any liability, loss, or damage resulting from such breach of security or
unauthorized disclosure or use.

REPETITIVE PAYMENT ORDERS- SECONDARY SECURITY PROCEDURE

         The Secondary Procedure is identical to the Primary Procedure
described above except that the Client chooses not to use the added precaution
of a Call-Back.  Client waives Call-Back verification for all Repetitive
Payment Orders.

By initialing above, Client acknowledges that payment orders will be verified
by a security procedure which is a higher-risk procedure and Client agrees to
assume all liability for unauthorized payment orders confirmed in accordance
with the higher-risk security procedure. 

WRITTEN PAYMENT ORDERS
DOMESTIC AND INTERNATIONAL

NON-REPETITIVE PAYMENT ORDERS-PRIMARY SECURITY PROCEDURE

All non-repetitive Payment Orders, including non-repetitive Payment Orders to
beneficiaries located outside the United States, must be written.  All
repetitive Payment Orders, at the election of Client, may be in writing.
Written transfers (signed by an Authorized Representative as listed in this
Authorized Representative Addendum) shall be in a form acceptable to Bank and
delivered in person or by fax.  Bank will perform a signature comparison to
verify that the individual whose signature appears on the written transfer
request is an Authorized Representative.  In addition, Bank will telephone a
second Authorized Representative to authenticate the transfer request.





                                       1
   38

                              SILICON VALLEY BANK
                            FUNDS TRANSFER AGREEMENT
                      SECURITY PROCEDURE SERVICE ADDENDUM





         This Addendum must be signed by an individual or individuals,
authorized by the corporate resolution or bylaws to sign Funds Transfer
Agreements.

                         Calypte Biomedical Corporation
                 ______________________________________________
                             (Print Name of Client)


_________________________                             _________________________
(BY)  Jack Davis                                      (BY) John DiPietro



President & CEO                                       VP & CFO
_________________________                             _________________________
(TITLE)                                               (TITLE)


12/19/95                                              12/19/95
_________________________                             _________________________
(Date)                                                (Date)







                                        2