1 EXHIBIT 11.1 INCYTE PHARMACEUTICALS, INC. STATEMENT RE COMPUTATION OF EARNINGS (LOSS) PER SHARE (In thousands, except per share amounts) Three Months Ended Six Months Ended June 30, June 30, ------------------- ------------------- 1997 1996 1997 1996 ------- ------- ------- ------- Primary Earnings (Loss) Per Share - --------------------------------- Weighted average common shares outstanding during the period 10,518 10,104 10,486 10,069 Adjustment for dilutive effect of outstanding stock options 916 -- 957 -- ------- ------- ------ ------ Weighted average common and common equivalent shares used for primary earnings (loss) per share 11,434 10,104 11,443 10,069 ======= ======= ======= ======= Net income (loss) 1,942 (1,596) 2,923 (3,634) ======= ======= ======= ======= Net income (loss) per share $ 0.17 ($ 0.16) $ 0.26 ($ 0.36) ======= ======= ======= ======= Fully Diluted Earnings (Loss) Per Share - --------------------------------------- Weighted average common shares outstanding during the period 10,518 10,104 10,486 10,069 Adjustment for dilutive effect of outstanding stock options 1,013 -- 1,006 -- ------- ------- ------- ------- Weighted average common and common equivalent shares used for fully diluted earnings (loss) per share 11,531 10,104 11,492 10,069 ======= ======= ======= ======= Net income (loss) 1,942 (1,596) 2,923 (3,634) ======= ======= ======= ======= Net income (loss) per share $ 0.17 ($ 0.16) $ 0.25 ($ 0.36) ======= ======= ======= ======= Page 16 of 17