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                                                                     Exhibit 3.1
                                                                          PAGE 1
                               State of Delaware

                        Office of the Secretary of State
                        --------------------------------

        I, EDWARD J. FREEL, SECRETARY OF STATE OF THE STATE OF DELAWARE, DO
HEREBY CERTIFY THE ATTACHED IS A TRUE AND CORRECT COPY OF THE RESTATED
CERTIFICATE OF "SPECTRX, INC.", FILED IN THIS OFFICE ON THE SEVENTH DAY OF
JULY, A.D. 1997, AT 11:30 O'CLOCK A.M.

        A CERTIFIED COPY OF THIS CERTIFICATE HAS BEEN FORWARDED TO THE NEW
CASTLE COUNTY RECORDER OF DEEDS FOR RECORDING.


[STATE OF DELAWARE SEAL]                  /s/ EDWARD J. FREEL
                                          -----------------------------------
                                          Edward J. Freel, Secretary of State

                                          AUTHENTICATION: 8546376
                                                    DATE: 07-08-97
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                     RESTATED CERTIFICATE OF INCORPORATION
                                       OF
                                 SPECTRX, INC.

        SPECTRX, INC., a corporation organized and existing under the laws of
the State of Delaware, the original Certificate of Incorporation of which was
filed on October 27, 1992 hereby certifies that the following Restated
Certificate of Incorporation (i) has been duly adopted in accordance with the
provisions of Section 245 of the General Corporation Law, (ii) restates the
provisions of the Certificate of Incorporation of SpectRx, Inc. filed with the
Secretary of State of the State of Delaware on September 30, 1996 and (iii)
supersedes the original Certificate of Incorporation and all prior restatements
thereof and amendments thereto in their entirety.

                                   ARTICLE I

        The name of the corporation is SpectRx, Inc. (the "Corporation").

                                   ARTICLE II

        The address of the Corporation's registered office in the State of
Delaware is 1209 Orange Street, City of Wilmington, County of New Castle,
Delaware 19801. The name of its registered agent at such address is The
Corporation Trust Company.

                                  ARTICLE III

        The purpose of the Corporation is to engage in any lawful act or
activity for which corporations may be organized under the General Corporation
Law of Delaware.

                                   ARTICLE IV

        The Corporation is authorized to issue two classes of shares of stock to
be designated, respectively, Common Stock, $0.001 par value, and Preferred
Stock, $0.001 par value. The total number of shares that the Corporation is
authorized to issue is $5,000,000 shares. The number of shares of Common Stock
authorized is 50,000,000. The number of shares of Preferred authorized is
5,000,000.

        The Preferred Stock may be issued from time to time in one or more
series pursuant to a resolution or resolutions providing for such issue duly
adopted by the board of directors (authority to do so being hereby expressly
vested in the board). The board of directors is further authorized to determine
or alter the rights, preferences, privileges and restrictions granted to or
imposed upon any wholly unissued series of Preferred Stock and to fix the
number of shares of any series of Preferred
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Stock and the designation of any such series of Preferred Stock. The board of
directors, within the limits and restrictions stated in any resolution or
resolutions of the board of directors originally fixing the number of shares
constituting any series, may increase or decrease (but not below the number of
shares in any such series then outstanding) the number of shares of any series
subsequent to the issue of shares of that series.

        The authority of the board of directors with respect to each such class
or series shall include, without limitation of the foregoing, the right to
determine and fix:

                (a)     the distinctive designation of such class or series and
the number of shares to constitute such class or series;

                (b)     the rate at which dividends on the shares of such class
or series shall be declared and paid, or set aside for payment, whether
dividends at the rate so determined shall be cumulative or accruing, and whether
the shares of such class or series shall be entitled to any participating or
other dividends in addition to dividends at the rate so determined, and if so,
on what terms;

                (c)     the right or obligation, if any, of the corporation to
redeem shares of the particular class or series of Preferred Stock and, if
redeemable, the price, terms and manner of such redemption;

                (d)     the special and relative rights and preferences, if any,
and the amount or amounts per share, which the shares of such class or series of
Preferred Stock shall be entitled to receive upon any voluntary or involuntary
liquidation, dissolution or winding up of the Corporation;

                (e)     the terms and conditions, if any, upon which shares of
such class or series shall be convertible into, or exchangeable for, shares of
capital stock of any other class or series, including the price or prices or the
rate or rates of conversion or exchange and the terms of adjustment, if any;

                (f)     the obligation, if any, of the corporation to retire,
redeem or purchase shares of such class or series pursuant to a sinking fund or
fund of a similar nature or otherwise, and the terms and conditions of such
obligation;

                (g)     voting rights, if any, on the issuance of additional
shares of such class or series or any shares of any other class or series of
Preferred Stock;

                (h)     limitations, if any, on the issuance of additional
shares of such class or series or any shares of any other class or series of
Preferred Stock; and 

                (i)     such other preferences, powers, qualifications, special
or relative rights and privileges thereof as the board of directors of the
corporation, acting in accordance with this

                                      -2-
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Restated Certificate of Incorporation, may deem advisable and are not
inconsistent with law and the provisions of this Restated Certificate of
Incorporation.

                                   ARTICLE V

        The Corporation reserves the right to amend, alter, change, or repeal
any provision contained in this Certificate of Incorporation, in the manner now
or hereafter prescribed by statute, and all rights conferred upon the
stockholders herein are granted subject to this right.

                                   ARTICLE VI

        The Corporation is to have perpetual existence.

                                  ARTICLE VII

        1.      Limitation of Liability. To the fullest extent permitted by the
General Corporation Law of the State of Delaware as the same exists or as may
hereafter be amended, a director of the Corporation shall not be personally
liable to the Corporation or its stockholders for monetary damages for breach
of fiduciary duty as a director.

        2.      Indemnification. The Corporation may indemnify to the fullest
extent permitted by law any person made or threatened to be made a party to an
action or proceeding, whether criminal, civil, administrative or investigative,
by reason of the fact that such person or his or her testator or intestate is or
was a director, officer or employee of the Corporation, or any predecessor of
the Corporation, or serves or served at any other enterprise as a director,
officer or employee at the request of the Corporation or any predecessor to the
Corporation.

        3.      Amendments. Neither any amendment nor repeal of this Article
VII, nor the adoption of any provision of the Corporation's Certificate of
Incorporation inconsistent with this Article VII, shall eliminate or reduce
the effect of this Article VII, in respect of any matter occurring, or any
action or proceeding accruing or arising or that, but for this Article VII,
would accrue or arise, prior to such amendment, repeal, or adoption of an
inconsistent provision.

                                  ARTICLE VIII

        In the event any shares of Preferred Stock shall be redeemed or
converted pursuant to the terms hereof, the shares so converted or redeemed
shall not revert to the status of authorized but unissued shares, but instead
shall be canceled and shall not be re-issuable by the Corporation.




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                                   ARTICLE IX


      Holders of stock of any class or series of this corporation shall not be
entitled to cumulate their votes for the election of directors or any other
matter submitted to a vote of the stockholders.

                                   ARTICLE X


        1.   Number of Directors.  The number of directors which constitutes
the whole Board of Directors of the corporation shall be designated in the
Bylaws of the corporation.

        2.   Election of Directors.  Election of directors need not be by
written ballot unless the Bylaws of the corporation shall so provide.

                                   ARTICLE XI

        In furtherance and not in limitation of the powers conferred by
statute, the Board of Directors is expressly authorized to make, alter, amend
or repeal the Bylaws of the corporation.

                                  ARTICLE XII

        Immediately upon the closing of a public offering pursuant to an
effective registration statement under the Securities Act of 1933, as amended,
covering any of the corporation's securities (as that term is defined under the
Securities Act of 1933, as then in effect), no action shall be taken by the
stockholders of the corporation except at an annual or special meeting of the
stockholders called in accordance with the Bylaws of the corporation and no
action shall be taken by the stockholders by written consent.

                                  ARTICLE XIII

        Meetings of stockholders may be held within or without the State of
Delaware, as the Bylaws may provide.  The books of the Corporation may be kept
(subject to any provision contained in the statutes) outside of the State of
Delaware at such place or places as may be designated from time to time by the
Board of Directors or in the Bylaws of the Corporation.

        This Restated Certificate of Incorporation has been duly adopted by the
board of directors of the Corporation in accordance with the provisions of
Section 242 and 245 of the General Corporation Law of the State of Delaware, as
amended.

        The Restated Certificate of Incorporation restates and integrates and
further amends the provisions of the Corporation's Certificate of Incorporation.

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        IN WITNESS WHEREOF, SpectRx, Inc. has caused this certificate to be
signed by Mark A. Samuels, its President, and Thomas H. Muller, Jr., Secretary,
this 3rd day of July, 1997.



                                By:  /s/ MARK A. SAMUELS
                                   ------------------------------------
                                   Mark A. Samuels, President


                                Attest:  /s/ THOMAS H. MULLER
                                       --------------------------------
                                       Thomas H. Muller, Jr., Secretary