1
                                                                   EXHIBIT 10.38


                           GENELABS TECHNOLOGIES, INC.

                             1995 STOCK OPTION PLAN

                             Adopted April 14, 1995
                (As Amended May 30, 1996 and September 17, 1997)

        1. PURPOSE. This 1995 Stock Option Plan (this "Plan") is established as
a compensatory plan to attract, retain and provide equity incentives to selected
persons to promote the financial success of Genelabs Technologies, Inc., a
California corporation (the "Company"). Capitalized terms not previously defined
herein are defined in Section 17 of this Plan.

        2. TYPES OF OPTIONS AND SHARES. Options granted under this Plan (the
"Options") may be either (a) incentive stock options ("ISOs") within the meaning
of Section 422 of the Internal Revenue Code of 1986, as amended (the "Code"), or
(b) non-qualified stock options ("NQSOs"), as designated at the time of grant.
The shares of stock that may be purchased upon exercise of Options granted under
this Plan (the "Shares") are shares of the Common Stock of the Company.

        3. NUMBER OF SHARES. Shares of Common Stock remaining available for
future grants of stock options under the Company's 1985 Employee Stock Option
Plan (the "1985 Plan") and shares of Common Stock issuable upon exercise or
currently outstanding pursuant to the 1985 Plan that expire or become
unexercisable for any reason without having been exercised in full, will be
available for issuance under the Plan, subject to adjustment as provided in this
Plan. Upon adoption of the Plan by the Company's shareholders on June 2, 1995,
the number of shares of Common Stock reserved for issuance under this Plan was
3,912,889. On May 30, 1996, the Company's shareholders approved an amendment to
increase the aggregate number of shares that may be issued pursuant to options
granted under this Plan to 4,912,889 shares. At all times during the term of
this Plan, the Company shall reserve and keep available such number of Shares as
shall be required to satisfy the requirements of outstanding Options under this
Plan.

        4. ELIGIBILITY. Options may be granted to employees, directors,
consultants , officers, independent contractors and advisers (provided such
consultants, independent contractors and advisers render bona fide services not
in connection with the offer and sale of securities in a capital-raising
transaction) of the Company or any Parent, Subsidiary or Affiliate of the
Company. ISOs may be granted only to employees (including officers and directors
who are also employees) of the Company or a Parent or Subsidiary of the Company.
Non-Employee Directors shall only be eligible for grants of NQSOs pursuant to
Section 7. The Committee (as defined in Section 14) in its sole discretion shall
select the recipients of Options ("Optionees"). An Optionee may be granted more
than one Option under this Plan. No one Optionee shall be eligible to receive
more than 800,000 Shares at any time during the term of this Plan pursuant to
the grant of Options hereunder.

             5. TERMS AND CONDITIONS OF OPTIONS. For grants other than to
 Non-Employee Directors pursuant to Section 7, the Committee shall determine
 whether each Option is to be an ISO or an NQSO, the number of Shares subject to
 the Option, the exercise price of the Option, the period during which the
 Option may be exercised, and all other terms and conditions of the Option,
 subject to the following:

                                       -1

   2

                     (a) Form of Option Grant. Each Option granted under this
 Plan shall be evidenced by a written Stock Option Grant (the "Grant") in such
 form (which need not be the same for each Optionee) as the Committee shall from
 time to time approve, which Grant shall comply with and be subject to the terms
 and conditions of this Plan.

                     (b) Date of Grant. The date of grant of an Option shall be 
the date on which the Committee makes the determination to grant such Option 
unless otherwise specified by the Committee. The Grant representing the Option 
will be delivered to Optionee with a copy of this Plan within a reasonable time 
after the granting of the Option.

                     (c) Exercise Price. The exercise price of an Option shall 
be determined by the Committee on the date the Option is granted; provided that 
(i) the exercise price of an NQSO shall be not less than 85% of the Fair Market
Value of the Shares on the date the Option is granted; (ii) the exercise price
of an ISO shall be not less than 100% of the Fair Market Value of the Shares on
the date the Option is granted; and (iii) the exercise price of any ISO granted
to a person owning more than l0% of the total combined voting power of all
classes of stock of the Company or any Parent or Subsidiary of the Company ("Ten
Percent Shareholder") shall not be less than 110% of the Fair Market Value of
the Shares on the date the Option is granted.

                     (d) Exercise Period. Options shall be exercisable within 
the times or upon the events determined by the Committee as set forth in the 
Grant; provided, however, that no Option shall be exercisable after the 
expiration of ten (10) years from the date the Option is granted, and provided 
further that no ISO granted to a Ten Percent Shareholder shall be exercisable 
after the expiration of five (5) years from the date the Option is granted.

                     (e) Limitations on ISOs. The aggregate Fair Market Value  
(determined as of the time an Option is granted) of stock with respect to which 
ISOs are exercisable for the first time by an Optionee during any calendar year 
(under this Plan or under any other incentive stock option plan of the Company 
or any Parent or Subsidiary of the Company) shall not exceed $100,000. If the 
Fair Market Value of Shares with respect to which ISOs are exercisable for the 
first time by an Optionee during any calendar year exceeds $100,000, the Options
for the first $100,000 worth of Shares to become exercisable in such year shall 
be ISOs and the Options for the amount in excess of $100,000 that become
exercisable in that year shall be NQSOs. In the event that the Code or the
regulations promulgated thereunder are amended after the effective date of this
Plan to provide for a different limit on the Fair Market Value of Shares
permitted to be subject to ISOs, such different limit shall be incorporated
herein and shall apply to any Options granted after the effective date of such
amendment.

                     (f) Options Non-Transferable. Options granted under this 
Plan, and any interest therein, shall not be transferable or assignable by 
Optionee, and may not be made subject to execution, attachment or similar 
process, otherwise than by will or by the laws of descent and distribution, 
and shall be exercisable during the lifetime of Optionee only by Optionee; 
provided, however, that NQSOs may be transferred to such family members, trusts 
and charitable institutions as the Committee, in its sole discretion, shall 
approve at the time of the grant of such Option.


                                       -2

   3

                     (g) Assumed Options. In the event the Company assumes an 
option granted by another company, the terms and conditions of such option shall
remain unchanged (except the exercise price and the number and nature of shares
issuable upon exercise, which will be adjusted appropriately pursuant to Section
424(a) of the Code). In the event the Company elects to grant a new option
rather than assuming an existing option, such new option may be granted with a
similarly adjusted exercise price.

             6.      EXERCISE OF OPTIONS.

                     (a) Notice. Options may be exercised only by delivery to 
the Company of a written stock option exercise agreement (the "Exercise 
Agreement") in a form approved by the Committee (which need not be the same 
for each Optionee), stating the number of Shares being purchased, the 
restrictions imposed on the Shares, if any, and such representations and 
agreements regarding Optionee's investment intent and access to information, if 
any, as may be required by the Company to comply with applicable securities 
laws, together with payment in full of the exercise price for the number of 
Shares being purchased.

                     (b) Payment. Payment for the Shares may be made in cash 
(by check) or, where approved by the Committee in its sole discretion at the 
time of grant and where permitted by law: (i) by cancellation of indebtedness 
of the Company to the Optionee; (ii) by surrender of shares of Common Stock of 
the Company having a Fair Market Value equal to the applicable exercise price 
of the Options, that have been owned by Optionee for more than six (6) months 
(and which have been paid for within the meaning of Securities and Exchange
Commission ("SEC") Rule 144 and, if such Shares were purchased from the Company
by use of a promissory note, such note has been fully paid with respect to such
shares), or were obtained by Optionee in the open public market; (iii) by tender
of a full recourse promissory note having such terms as may be approved by the
Committee and bearing interest at a rate sufficient to avoid imputation of
income under Sections 483 and 1274 of the Code; (iv) by waiver of compensation
due or accrued to Optionee for services rendered; (v) provided that a public
market for the Company's stock exists, through a "same day sale" commitment from
Optionee and a broker-dealer that is a member of the National Association of
Securities Dealers (an "NASD Dealer") whereby Optionee irrevocably elects to
exercise the Option and to sell a portion of the Shares so purchased to pay for
the exercise price and whereby the NASD Dealer irrevocably commits upon receipt
of such Shares to forward the exercise price directly to the Company; (vi)
provided that a public market for the Company's stock exists, through a "margin"
commitment from Optionee and an NASD Dealer whereby Optionee irrevocably elects
to exercise the Option and to pledge the Shares so purchased to the NASD Dealer
in a margin account as security for a loan from the NASD Dealer in the amount of
the exercise price, and whereby the NASD Dealer irrevocably commits upon receipt
of such Shares to forward the exercise price directly to the Company; or (vii)
by any combination of the foregoing. Optionees who are not employees of the
Company shall not be entitled to purchase Shares with a promissory note unless
the note is adequately secured by collateral other than the Shares.

                     (c) Withholding Taxes. Prior to issuance of the Shares upon
exercise of an Option, Optionee shall pay or make adequate provision for any 
federal or state withholding obligations of the Company, if applicable.



                                       -3

   4

                     (d) Limitations on Exercise. Notwithstanding the exercise  
periods set forth in the Grant, exercise of an Option shall always be subject to
the following:

                        (i) If  Optionee  ceases to be  employed or retained by 
the Company or any Parent, Subsidiary or Affiliate of the Company for any reason
except death or disability, Optionee may exercise such Optionee's ISOs or NQSOs
to the extent (and only to the extent) that they would have been exercisable 
upon the date of termination, within three (3) months after the date of 
termination (or such shorter time period as may be specified in the Grant).

                       (ii) If  Optionee's employment or retention with the 
Company or any Parent, Subsidiary or Affiliate of the Company is terminated 
because of the death of Optionee or disability of Optionee within the meaning 
of Section 22(e)(3) of the Code, Optionee's ISOs or NQSOs may be exercised to 
the extent (and only to the extent) that they would have been exercisable by 
Optionee on the date of termination, by Optionee (or Optionee's legal 
representative) within twelve (12) months after the date of termination (or such
shorter time period as may be specified in the Grant), but in any event no later
than the expiration date of the ISOs.

                      (iii) The Committee shall have discretion to determine  
whether Optionee has ceased to be employed or retained by the Company or any 
Parent, Subsidiary or Affiliate of the Company and the effective date on which 
such employment terminated.

                       (iv) In the case of an Optionee who is a director, 
consultant, independent contractor or adviser, the Committee will have the 
discretion to determine whether Optionee is employed or retained by the Company 
or any Parent, Subsidiary or Affiliate of the Company pursuant to the foregoing 
Sections.

                        (v) The Committee may specify a reasonable minimum 
number of Shares that may be purchased on any exercise of an Option, provided 
that such minimum number will not prevent Optionee from exercising the full 
number of Shares as to which the Option is then exercisable.

                       (vi) An Option shall not be exercisable unless such 
exercise is in compliance with the Securities Act of 1933, as amended (the 
"Securities Act"), all applicable state securities laws and the requirements of 
any stock exchange or national market system upon which the Shares may then be 
listed, as they are in effect on the date of exercise. The Company shall be 
under no obligation to register the Shares with the SEC or to effect compliance 
with the registration, qualification or listing requirements of any state 
securities laws, stock exchange or national market system, and the Company 
shall have no liability for any inability or failure to do so.

             7.   OPTION GRANTS FOR NON-EMPLOYEE DIRECTORS

                     (a)Eligibility and Award Formula. Options may be granted
                        only to such Non-Employee Directors of the Company or
                        any Parent, Subsidiary or Affiliate of the Company as
                        the Committee shall select from time to time in its sole
                        discretion. Directors may be granted more than one
                        option under the Plan. 

                                       -4

   5

                        Each director, upon his or her first election to the 
                        Board, will be granted an option to purchase 20,000 
                        shares of the Company's Common Stock. At the Company's 
                        Annual Meeting of Shareholders following the second 
                        anniversary of his or her election to the Board, and at 
                        each subsequent Annual Meeting of Shareholders, each 
                        director will be granted an additional option to 
                        purchase 5,000 shares.

                    (b) Terms and Conditions of Options. The Committee shall 
                        determine the exercise  price of the Option, the period 
                        during which the Option may be exercised, and all other 
                        terms and conditions of the Option, subject to the 
                        following:

                            (i) Date of Grant. The date of grant of an Option
                                shall be the dates described in Section 7 (a)
                                above. The Grant representing the Option will be
                                delivered to the Optionee within a reasonable
                                time after the granting of the Option.

                           (ii) Exercise Price. The exercise price of an Option
                                shall be not less than the Fair Market Value of
                                the Shares at the time that the Option is
                                granted.

                          (iii) Exercise Period. Options shall be exercisable
                                as to 50% of the Shares on the first anniversary
                                of the date of grant and the remaining 50% on
                                the second anniversary thereof; provided
                                however, that no Option shall be exercisable
                                after the expiration of five years from the date
                                the Option is granted.

                           (iv) Limitation on Exercise. If the Optionee ceases
                                to be a director for any reason except death or
                                disability, Optionee may exercise his or her
                                options to the extent (and only to the extent)
                                that they would have been exercisable upon the
                                date of termination, within six (6) months after
                                the date of termination. If the Optionee ceases
                                to be a director because of death or disability,
                                Optionee (or Optionee's legal representative)
                                may exercise his or her options to the extent
                                (and only to the extent) that they would have
                                been exercisable upon the date of termination,
                                within twelve (12) months after the date of
                                termination.

             8. MODIFICATION, EXTENSION AND RENEWAL OF OPTIONS. The Committee
shall have the power to modify, extend or renew outstanding Options and to
authorize the grant of new Options in substitution therefor, provided that any
such action may not, without the written consent of Optionee, impair any rights
under any Option previously granted. Any outstanding ISO that is modified,
extended, renewed or otherwise altered shall be treated in accordance with
Section 424(h) of the Code. The Committee shall have the power to reduce the


                                       -5


   6



exercise price of outstanding Options without the consent of Optionees by a
written notice to the Optionees affected; provided, however, that the exercise
price per Share may not be reduced below the minimum exercise price that would
be permitted under Section 5(c) of this Plan for Options granted on the date the
action is taken to reduce the exercise price.

             9. PRIVILEGES OF STOCK OWNERSHIP. No Optionee shall have any of the
rights of a shareholder with respect to any Shares subject to an Option until
such Option is properly exercised. No adjustment shall be made for dividends or
distributions or other rights for which the record date is prior to such date,
except as provided in this Plan. Upon written request, the Company shall provide
to each Optionee a copy of the annual financial statements of the Company at
such time after the close of each fiscal year of the Company as such statements
are released by the Company to its common shareholders generally.

             10. NO OBLIGATION TO EMPLOY. Nothing in this Plan or any Option
granted under this Plan shall confer on any Optionee any right to continue in
the employ of, as a director of, or other relationship with, the Company or any
Parent, Subsidiary or Affiliate of the Company or limit in any way the right of
the Company or any Parent, Subsidiary or Affiliate of the Company to terminate
Optionee's employment or other relationship at any time, with or without cause.

             11. ADJUSTMENT OF OPTION SHARES. In the event that the number of
outstanding shares of Common Stock of the Company is changed by a stock
dividend, stock split, reverse stock split, combination, reclassification or
similar change in the capital structure of the Company without consideration, or
if a substantial portion of the assets of the Company are distributed, without
consideration in a spin-off or similar transaction, to the shareholders of the
Company, the number of Shares available under this Plan and the number of Shares
subject to outstanding Options and the exercise price per Share of such Options
shall be proportionately adjusted, subject to any required action by the Board
of Directors (the "Board") or shareholders of the Company and compliance with
applicable securities laws; provided, however, that a fractional share shall not
be issued upon exercise of any Option and any fractions of a Share that would
have resulted shall either be cashed out at Fair Market Value or the number of
Shares issuable under the Option shall be rounded up to the nearest whole
number, as determined by the Committee; and provided further that the exercise
price may not be decreased to below the par value, if any, for the Shares.

             12. ASSUMPTION OF OPTIONS BY SUCCESSORS. In the event of a
dissolution or liquidation of the Company, a merger in which the Company is not
the surviving corporation, a transaction in which 100% of the then-outstanding
voting stock is sold or otherwise transferred or the sale of substantially all
of the assets of the Company any or all outstanding Options shall,
notwithstanding any contrary terms of the Grant, accelerate and become
exercisable in full at least 10 days prior to (and shall expire on) the
consummation of such dissolution, liquidation, merger or sale of assets on such
conditions as the Committee shall determine unless the successor corporation
assume the outstanding options or substitutes substantially equivalent options.
The aggregate Fair Market Value of ISOs which first become exercisable in the
year of such dissolution, liquidation, merger or sale of assets cannot exceed
$100,000. Any remaining accelerated options shall be treated as NQSOs.


                                       -6


   7
            13. ADOPTION AND SHAREHOLDER APPROVAL. This Plan shall become
effective on the date that it is adopted by the Board of the Company. This Plan
shall be approved by the shareholders of the Company, in any manner permitted by
applicable corporate law, within twelve months before or after the date this
Plan is adopted by the Board. Upon the effective date of the Plan, the Board may
grant Options pursuant to this Plan; provided that, in the event that
shareholder approval is not obtained within the time period provided herein, all
Options granted hereunder shall terminate. No Option that is issued as a result
of any increase in the number of shares authorized to be issued under this Plan
shall be exercised prior to the time such increase has been approved by the
shareholders of the Company and all such Options granted pursuant to such
increase shall similarly terminate if such Shareholder approval is not obtained.

             14. ADMINISTRATION. This Plan may be administered by the Board or a
committee appointed by the Board (the "Committee"). As used in this Plan,
references to the "Committee" shall mean either such Committee or the Board if
no Committee has been established. If the Company is registered under the
Exchange Act and two or more members of the Board are Non-Employee Directors,
the Committee shall be comprised of at least two members of the Board, all of
whom are Non-Employee Directors. The interpretation by the Committee of any of
the provisions of this Plan or any Option granted under this Plan shall be final
and binding upon the Company and all persons having an interest in any Option or
any Shares purchased pursuant to an Option. The Committee may delegate to
officers of the Company the authority to grant Options under this Plan to
Optionees who are not officers or directors of the Company whose transactions in
the Company's Common Stock are subject to Section 16(b) of the Exchange Act.

             15. TERM OF PLAN. Options may be granted pursuant to this Plan from
time to time within a period of ten (10) years from the date on which this Plan
is adopted by the Board.

             16. AMENDMENT OR TERMINATION OF PLAN. The Committee may at any time
terminate or amend this Plan in any respect including (but not limited to)
amendment of any form of grant, exercise agreement or instrument to be executed
pursuant to this Plan; provided, however, that the Committee shall not, without
the approval of the shareholders of the Company, amend this Plan in any manner
that requires such shareholder approval pursuant to the Code or the regulations
promulgated thereunder as such provisions apply to ISO plans or pursuant to the
Exchange Act or Rule 16b-3 (or its successor) promulgated thereunder.17.

             17. CERTAIN DEFINITIONS. As used in this Plan, the following terms
             shall have the following meanings:

                     (a) "Parent" means any corporation (other than the Company)
in an unbroken chain of corporations ending with the Company if, at the time of 
the granting of the Option, each of such corporations other than the Company 
owns stock possessing 50% or more of the total combined voting power of all 
classes of stock in one of the other corporations in such chain.

                                       -7



   8



                     (b) "Subsidiary" means any corporation (other than the 
Company) in an unbroken chain of corporations beginning with the Company if, at 
the time of granting of the Option, each of the corporations other than the last
corporation in the unbroken chain owns stock possessing 50% or more of the total
combined voting power of all classes of stock in one of the other corporations 
in such chain.

                     (c) "Affiliate" means any corporation that directly, or 
indirectly through one or more intermediaries, controls or is controlled by, or 
is under common control with, another corporation, where "control" (including 
the terms "controlled by" and "under common control with") means the possession,
direct or indirect, of the power to cause the direction of the management and 
policies of the corporation, whether through the ownership of voting securities,
by contract or otherwise.

                     (d) "Fair Market Value" shall mean the fair market value of
the Shares as determined by the Committee from time to time in good faith. If a
public market exists for the Shares, the Fair Market Value shall be the average
of the last reported bid and asked prices for common stock of the Company on the
last trading day prior to the date of determination, or in the event the common
stock of the Company is listed on the Nasdaq National Market, the Fair Market
Value shall be the average of the high and low prices of the common stock on the
option grant date as quoted on the Nasdaq National Market and reported in the
Wall Street Journal.

                     (e) "Non-Employee Director" means a Director who either 
(i) is not a current Employee or Officer of the Company or its parent or 
subsidiary, does not receive compensation (directly or indirectly) from the 
Company or its parent or subsidiary for services rendered as a consultant or in 
any capacity other than as a Director (except for an amount as to which 
disclosure would not be required under Item 404(a) of Regulation S-K promulgated
pursuant to the Securities Act ("Regulation S-K")), does not possess an interest
in any other transaction as to which disclosure would be required under Item 
404(a) of Regulation S-K, and is not engaged in a business relationship as to 
which disclosure would be required under Item 404(b) of Regulation S-K; or 
(ii) is otherwise considered a "non-employee director" for purposes of 
Rule 16b-3.


                                      -8