1 Exhibit 10.82 FIRST AMENDMENT TO LEASE SCHEDULE MASTER PROPERTY LEASE AGREEMENT NO. 943 DATED MARCH 29, 1994 SCHEDULE NO. 3 DATED MARCH 29, 1994 The Initial Term of the Lease for the Units covered by the Schedule No. 3 to the Master Property Lease Agreement No. 943, is hereby extended beyond the original expiration date of August 31, 1997 of the Lease Schedule such that the lease term will continue through NOVEMBER 30, 1999. The rent per month during the extended term, beginning December 1, 1997 and continuing through November 30, 1999, shall be $3,472.30, plus applicable taxes. The rental payments during the extended lease term shall be made monthly in advance on the first day of each month, beginning on December 1, 1997. Section 6 of the Lease Schedule shall be replaced with the following new Section 6: Provided that the Lease has not been terminated and that no Event of Default or event which, with notice or lapse of time or both, would become an Event of Default shall have occurred and be continuing, and provided that all rents and other payments due under the Lease shall have been paid, title to the Units covered by the schedule for Special Equipment under the Lease shall pass to Lessee at the end of the extended lease term. Except as specifically amended hereby, Schedule No. 3 shall be and remain in full force and effect. This Amendment has been entered into, and is made a part of the above referenced Schedule, as of October 29, 1997. ARRIS PHARMACEUTICAL HAMBRECHT & QUIST CORPORATION GUARANTY FINANCE, LLC By: /s/ Frederick Ruegsegger By: /s/ Donald M. Campbell --------------------------- -------------------------- Name: Frederick Ruegsegger Name: Donald M. Campbell ------------------------- ------------------------ Title: VP & CFO Title: Chief Executive Officer ------------------------ ----------------------- First Amendment to Schedule No. 3 to Master Property Lease Agreement No. 943