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                                                                    Exhibit 10.5

                                 LEASE AGREEMENT

      This Lease Agreement is made this 12th day of December 1997, between
MYRIAD DEVELOPERS, L.C., an Iowa limited liability company, (the "LANDLORD") and
UROSURGE, INC., A Delaware corporation, (the "TENANT")

                                    Schedule


                               
NAME OF TENANT:                   UroSurge, Inc.
LOCATION OF BUILDING:             Oakdale Campus (Building 2)
                                  Coralville, Iowa
LEGAL DESCRIPTION:                A portion of Lot 4, Oakdale Research Park
                                  See attached.
DESCRIPTION OF LEASED             11,500 square feet located in the
PREMISES:                         center and east end of the Building.
TENANT'S USE OF PREMISES:         office space
RENTABLE SQUARE FEET:             11,500
ANNUAL BASE RENT:                 $96,600.00
MONTHLY RENT:                     $8,050
RATE PER SQUARE FOOT PER YEAR:    $8.40, plus additional rent, subject to adjustment
TERM OF LEASE:                    29 months with one five-year
                                  option to renew.
COMMENCEMENT DATE:                January 1, 1998
TOTAL RENTABLE SQUARE FOOTAGE
IN BUILDING:                      14,904
PROPORTIONATE SHARE OF TAXES,
INSURANCE, MAINTENANCE AND
OTHER EXPENSES:                   As set by Landlord.
REQUIRED DEPOSIT:                 None
PARKING:                          33 spaces surrounding the Building.
TERMINATION DATE OF LEASE:        29 months from commencement date subject to option.



LANDLORD -- MYRIAD DEVELOPERS, L.C.
            an Iowa limited liability company


            By  /s/ PATRICK H. MURPHY
                ------------------------------------
                MANAGER                      , AGENT
                -----------------------------


TENANT   -- UROSURGE, INC.
            A Delaware corporation


            By  [SIG]
                ------------------------------------
                PRES. & C.E.O.
                ------------------------------------


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      1. LEASING AGREEMENT AND TERM. Landlord hereby leases to Tenant, and 
Tenant hereby leases the Premises, from the Landlord for a term commencing
January 1, 1998, and terminating June 1, 2000 unless sooner terminated or
renewed according to the terms hereof. The Premises shall be occupied and used
by the Tenant only for the uses described herein.

      2. USE OF PREMISES. The Premises shall be occupied and used by the Tenant
only for those purposes and uses allowable hereunder. The Tenant's use, and this
Lease, are subject to the terms and conditions of a certain Land Lease entered
into on the 31st day of October 1994, by and between IOWA RESEARCH PARK
CORPORATION, as "Lessor" and MYRIAD DEVELOPERS, L.C., as "Lessee," a copy of
which is attached hereto. The Tenant represents that it has reviewed all
provisions contained therein, including those provisions applicable to the use
of the Building and Tenant covenants it shall comply with the terms and
conditions thereof applicable to Tenant. The Tenant hereby represents that the
Premises will be used for the following purposes: laboratory; business and
administrative; offices for research, development, marketing, and sales
activities; and light manufacturing. Any changes in said use shall be subject to
and in compliance with the provisions hereof.

      3. RENT. Tenant shall pay to Landlord at Landlord's office in the City of
Cedar Rapids, Iowa or to such other person or at such other place as directed
from time to time by notice to the Tenant from Landlord the annual base rent as
set forth in the Schedule in equal monthly installments as set forth in the
Schedule. Each monthly installment shall be payable in advance promptly on the
first day of each calendar month during the term of this Lease and shall bear
interest at the rate of 10 percent (10%) per annum from and after the l0th day
of the month if not then paid until the date when paid. If the term should
commence or terminate on a day other than the first day of the month, then the
rent for the first and last month shall be prorated for such fractional month.
All rent payable by Tenant hereunder shall be net to Landlord. All expenses and
obligations of every kind and nature whatsoever relating to the Building, which
may arise or become due during the term of this Lease including, but not limited
to, taxes, utilities, insurance, and maintenance shall be paid by the Tenant and
Tenant shall indemnify and hold the Landlord harmless from said expenses. This
Lease is a net Lease and Landlord shall have no expenses associated with the 
Building.

      4. ADDITIONAL RENT. In addition to the base rent provided for above and on
the schedule, the Tenant shall pay, as additional rent, the following:

            A.    Taxes and Special Assessments. The Tenant shall pay, as
                  additional rent, its proportionate share of the real estate
                  taxes accruing from the commencement date and all special
                  assessments due and payable during the Lease term, and a
                  prorated share of all taxes and special assessments becoming
                  payable after the termination of the Lease for

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                  periods during the term of the Lease, which amounts shall be
                  paid monthly with the base rent. The Landlord shall notify the
                  Tenant of any increases in taxes during the term of this
                  Lease. All other sums required to be paid by tenant hereunder
                  shall be deemed additional rent. Tenant's proportionate share
                  shall be rentable square feet (11,SOO square feet) divided by
                  total rentable square footage in the building (14,904 square
                  feet) times the actual taxes for building number two and taxes
                  for the associated parking.

            B.    Insurance. The Tenant shall pay and reimburse the Landlord,
                  upon request by the Landlord, its proportionate share of the
                  cost of insurance procured and maintained by the Landlord
                  hereunder as per section 11 of the Agreement based on the
                  square footage of the Leased Premises compared to the total
                  square footage of the Building. All sums requested hereunder
                  by the Landlord shall be paid by the Tenant within 15 days
                  thereof, or the Landlord has the right to require the Tenant
                  to pay one-twelfth of the cost of all insurance monthly with
                  the base rent. Tenant's proportionate share shall be rentable
                  square feet (11,500 square feet) divided by total rentable
                  square footage in the building (14,904 square feet) times the
                  cost of insurance procured and maintained by the Landlord as
                  described above.

            C.    Maintenance. The Tenant shall pay its proportionate share of
                  all the costs of maintaining, repairing, operating and
                  replacing all improvements to the real estate on which the
                  rental premises is located including, but not limited to,
                  parking lot, lighting, exterior maintenance of the Building,
                  hallways, entryways, heating, cooling, and ventilating
                  systems, any and all facilities and services provided to the
                  Building (except where the Tenant is responsible for all such
                  costs hereunder), snow removal, care of lawn and landscaping,
                  and utilities. The Tenant shall pay to the Landlord, upon
                  demand, monthly with all other sums due hereunder, Tenant's
                  proportionate share of all such maintenance costs incurred by
                  Landlord. Tenant's proportionate share shall be rentable
                  square feet (11,500 square feet) divided by total rentable
                  square footage in the Myriad Technology Plaza (currently
                  24,908 square feet), located on lot 4 of the Oakdale Research
                  Park, times maintenance costs for the complex; excluding
                  replacement of HVAC and EDPM roof for the complex

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                  buildings. Tenant shall also contribute a proportionate share
                  to reserve for replacement EDPM roof and HVAC. Tenants annual
                  share to reserve replacement EDPM roof and HVAC shall be
                  $3,570 to be paid monthly with all other sums due hereunder.

      5. Utilities. Landlord will furnish nonducted heating, ventilation and air
conditioning, telephone, electric service and plumbing as described in paragraph
19 hereof. Tenant will pay for all utility costs and charges during the lease
term with respect to the Premises upon demand by the Landlord. The Premises
shall be separately metered and the Tenant shall pay all such utility charges
directly to the provider.

      6. Services. Tenant shall keep the Premises clean, neat, and shall provide
its own janitor and cleaning services. Tenant will keep the windows clean inside
and keep the inner walls painted or washed to maintain a neat appearance.

      7. Parking. The Tenant for itself and its invitees and guests shall have
use of the space surrounding the Building which has been constructed by the
Landlord for parking purposes, subject to parking rights granted to other
tenants and their invitees. The Tenant shall have the exclusive use of 33
parking spaces requested by Tenant.

      8. Recording. Except for recording of a memorandum of this Lease which may
be accomplished only if approved by Landlord, nothing contained shall empower
Tenant to do any act which can, shall or may encumber the interest or title of
Landlord or its assignee in and to the ground or Building.

      9. Mortgage by Landlord. From time to time either before or after the
execution of this Lease and before the termination of the term thereof, Landlord
may execute a mortgage or trust deed in the nature of a mortgage of Landlord's
interest in the Building. IN SUCH EVENT:

            A.    If requested by the mortgagee or trustee, Tenant will
                  subordinate its interest in this Lease to said mortgage or
                  trust deed and will execute such subordination agreement or
                  agreements as may he reasonably required by said mortgagee or
                  trustee, provided, however, that so long as Tenant shall not
                  be in default under this Lease, its right of possession and
                  enjoyment of the Premises shall be and remain undisturbed and
                  unaffected by said mortgage or trust deed or by any
                  foreclosure proceedings thereunder, and any subordination
                  agreement executed pursuant to this paragraph shall contain
                  language specifically so providing.

            B.    Should such mortgage be foreclosed, the liability of the
                  mortgagee, trustee or purchaser at such

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                  foreclosure sale or the liability of a subsequent owner
                  designated as Landlord under this Lease, shall exist only so
                  long as such trustee, mortgagee, purchaser or owner is the
                  owner of the subject real estate and such liability shall not
                  continue or survive after further transfer of ownership.

            C.    Landlord agrees promptly to notify Tenant of the placing of
                  any mortgage or trust deed against the leasehold estate of
                  which the Building forms a part and Tenant agrees in the event
                  of any act or omission by Landlord which would give Tenant the
                  right to terminate this Lease or to claim a partial or total
                  eviction, Tenant shall not exercise any such right (i) until
                  it has notified in writing the holder of any mortgage which at
                  the time shall be a lien on the Building, if the name and
                  address of such holder shall previously have been furnished by
                  written notice to Tenant, of such act or omission, and (ii)
                  until a reasonable period, not exceeding thirty (30) days, for
                  commencing the remedying of such act or omission shall have
                  lapsed following the giving of such notice, and (iii) such
                  holder, with reasonable diligence shall not have so commenced
                  and continued to remedy such act or omission or to cause the
                  same to be remedied. During the period between the giving of
                  such notice and the remedying of such act or omission, the
                  rental herein recited shall be abated and apportioned to the
                  extent that any part of the Building shall be untenantable.

            D.    If such mortgage be foreclosed, upon request of the mortgagee
                  or trustee, Tenant will attorn to the purchaser at any
                  foreclosure sale thereunder and will execute such instruments
                  as may be necessary or appropriate to evidence such
                  attornment. Likewise Tenant will attorn to the leasehold
                  mortgagee in the event said leasehold mortgagee should ever
                  become the owner of the leasehold estate covered by its
                  mortgage or should become the owner of any new lease in
                  replacement or substitution of such leasehold estate.

      10. Certain Rights Reserved to the Landlord. The Landlord preserves the
following rights:

            A.    Occupancy. During the last one hundred twenty (120) days of
                  the term of this Lease, if during or prior to that time the
                  Tenant vacates the Premises,

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                  to decorate, remodel, repair, alter or otherwise prepare the
                  Premises for reoccupancy.

            B.    Pass keys. To have pass keys to the Premises for access to the
                  Premises in the event of emergencies requiring Landlord's
                  action to prevent or limit damages to the Building.

            C.    Access for Inspections. To have access for the purpose of
                  inspecting the condition of the Premises, at convenient times
                  and with reasonable advance notice provided to Tenant.

            D.    Show Building. To show the Premises to prospective tenants or
                  brokers during the last 120 days of the term of this Lease as
                  extended, and to prospective purchasers at all reasonable
                  times provided prior notice is given to Tenant in each case
                  and the Tenant's use and occupancy of the Premises shall not
                  be materially inconvenienced by any such action of the
                  Landlord.

            E.    Heavy Equipment. To approve the weight, size and location of
                  safes or heavy equipment of articles which articles may be
                  moved, in, about, or out of the Premises only at such times
                  and in such manner as Landlord shall approve and, in all
                  events, however, at Tenant's sole risk and responsibility.

      The Landlord may enter the Premises and may exercise any or all of the
foregoing rights hereby reserved without being deemed guilty of an eviction or
disturbance of the Tenant's use or possession and without being liable in any
manner to the Tenant.

      11. Liability Claims. Tenant waives all claims it may have against
Landlord, its agents or Employees for damage to person or property sustained by
Tenant or any occupant or other person resulting from any cause, except if
caused by the negligence of the Landlord, its agents or employees.

      Landlord shall carry fire and extended coverage insurance insuring the
full replacement value of the Premises provided by the Landlord, and Tenant
shall waive any rights of action against Landlord for loss or damage covered by
such insurance, and the policies shall permit such waiver. Tenant shall
reimburse the Landlord for the proportionate share of cost of said insurance and
all other insurance the Landlord deems necessary, as provided in paragraph 4
above. Tenant shall carry fire and extended coverage insurance insuring the full
replacement value of Tenant improvements in the Building and its interest in
furniture, and supplies, and Tenant shall waive any rights of action against
Landlord for loss or damage covered by such insurance, and the policies shall
permit such waiver.

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      Tenant will secure and maintain general liability insurance naming the
Tenant and Landlord as insureds from financially responsible insurance
companies. If Tenant occupies space in which there is exterior plate glass, then
Tenant shall be responsible for the damage, breakage or repair of such plate
glass. If any damage to the Building results from any act or neglect of the
Tenant, the Landlord may at the Landlord's option, without any obligation to do
so, repair such damage, and the Tenant shall thereupon pay to the Landlord the
total cost of such repairs and damages to the Building.

      The parties agree that Tenant shall maintain public liability insurance,
pursuant to the terms of this paragraph, with minimum limits of $1,000,000
aggregate and shall furnish the certificate to Landlord showing said insurance
is in full force and effect.

      12. Conditions of Building. During the term of this Lease, Tenant shall
maintain, at its sole cost, in good condition and repair, the Premises, all
leasehold improvements contained therein and all components including, but not
limited to utilities, heating, ventilating, and cooling systems, electrical and
plumbing, and plate glass for which the Tenant is responsible hereunder. In the
event the Tenant fails to maintain the Premises as required by this paragraph,
then the Landlord may restore the Premises in such condition, and the Tenant
shall pay the costs thereof. Failure of the Tenant to fulfill its obligations of
this paragraph, shall constitute a default hereunder. At the termination of the
lease, the Tenant shall return the Premises to the Landlord in good condition
and repair with reasonable wear and tear excepted, and, if the Tenant does not
default hereunder, the Tenant may remove any removable fixtures other than light
fixtures and other like equipment installed by the Tenant if, and only if, such
removals are done and good and workmanlike manner and if the Premises and all
surfaces are restored to conditions reasonably acceptable to the Landlord.

      13. Alterations. After construction of the Building by Landlord and
completion of fixtures and interior improvements by Tenant, Tenant shall not
make alterations in or additions to the Building unless Tenant has obtained
Landlord's written permission to do so, and subject to Tenant's not being in
default hereunder and subject to furnishing Landlord with acceptable plans and
specifications, the names and addresses of contractors, copies of contracts,
necessary permits and indemnifications as requested by the Landlord and lien
waivers as to any and all claims, costs, liabilities, and expenses which may
arise in connection with said alterations or additions. As a further condition
to Landlord's consent to said alterations or additions, Tenant shall advise all
subcontractors, suppliers, materialmen, and laborers that they shall not have
the right to file a Mechanic's Lien against the Building and property owned by
the Landlord. Whether the Tenant furnished the Landlord the foregoing or not,
the Tenant hereby agrees to hold the Landlord harmless from any and all
liabilities of every kind and description which may arise out of or be conducted
in any way with said alterations or additions. Before commencing any work in
connection

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with alterations or additions, the Tenant, if requested by Landlord, shall
furnish the Landlord with certificates of insurance from all contractors
performing labor or furnishing materials insuring the Landlord against any and
all liabilities which may arise out of or be connected in any way with said
additions or alterations. The Tenant shall pay the cost of all such alterations
and additions and also the cost of decorating the Premises occasioned by such
alterations and additions.

      Upon completing any alterations or additions, the Tenant, if requested by
Landlord, shall furnish the Landlord with contractors' affidavits and full and
final waiver of lien and receipted bills covering all labor and material
expended and used. All alterations and additions shall comply with all insurance
requirements and with all relevant laws, ordinances, or regulations of
municipalities, counties, state, and other governmental units or departments and
agencies thereof. All alterations and additions shall be constructed in a good
and workmanlike manner and only good grades of materials shall be used. All
additions, excepting removable fixtures other than light fixtures, shall become
the Landlord's property and shall remain upon the Premises at the termination of
this Lease by lapse of time or otherwise without compensation or allowance or
credit to the Tenant. If the Tenant does not remove the Tenant's fixed
furniture, equipment, machinery, fixtures, and all other items of personal
property of every kind and description from the Premises prior to the end of the
term, however ended, which the Tenant does not have the right to remove if it is
in default hereunder, then Tenant shall conclusively presumed to have conveyed
the same to the Landlord under this Lease as a bill of sale without further
payment or credit by Landlord to the Tenant. All structural changes made by
Tenant shall be restored to their original condition at the Tenant's expense if
Landlord so requests. Tenant's violation of any of the terms and conditions of
this numbered paragraph 13 shall constitute a default hereunder.

      14. Rules and Regulations. The Tenant shall abide by all reasonable rules
and regulations adopted by Landlord pertaining to the operation and management
of the Building. if any rules and regulations are contrary to the terms of this
Lease, the terms of the Lease shall govern.

      15. Damage or Destruction.

          A.   Damage or Destruction of Premises Provided by the Landlord. If
               the Premises or any part thereof shall be damaged or partially
               destroyed by fire or any other casualty, the Tenant shall
               promptly notify the Landlord, and the Landlord will repair or
               rebuild the Premises, except as hereinafter provided. The
               restoration shall commence within ninety (90) days from the date
               of damage or partial destruction, provided, however, the Landlord
               may be granted such extensions of time for the adjustment

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                  of insurance and the preparation of plans and specifications
                  as reasonably may be required.

                  No partial destruction or damage to the Premises or any part
                  thereof shall permit the Tenant to surrender this Lease or
                  relieve the Tenant from its obligations to pay rent or from
                  any other obligations hereunder. The Tenant waives any rights
                  now or in the future conferred upon it by statute or otherwise
                  to quit or surrender this Lease or to any rebate, refund,
                  suspension, diminution, abatement, or reduction of rent on
                  account of any partial destruction or damage to the Building.

                  If the Premises is totally destroyed by fire or any other
                  casualty, Tenant may elect to terminate this lease and
                  promptly notify the Landlord, in writing, within thirty (30)
                  days after the date of damage or destruction, and this Lease
                  shall thereupon terminate. In the event the Tenant does not
                  elect to terminate this Lease in case of total destruction,
                  then the Landlord shall repair or rebuild the Premises, using
                  any and all insurance proceeds therefor.

                  The Tenant hereby acknowledges that any and all insurance
                  proceeds payable upon damage or destruction to the Premises,
                  shall be payable to the Landlord and the Landlord may apply
                  and use said proceeds as it deems appropriate, in its sole
                  discretion.

            B.    Damage or Destruction of Tenant Interior Improvements. If the
                  Tenant-provided interior improvements thereof shall be damaged
                  or partially destroyed by fire or other casualty, the Tenant
                  shall notify the Landlord, and, at the Tenant's sole cost and
                  expense, and whether or not the insurance proceeds are
                  sufficient, restore, repair, replace, or rebuild such
                  Tenant-provided interior improvements. Said restoration shall
                  be at least equal in quality and class to the original
                  construction, shall be of a design approved in writing by the
                  Landlord, shall be performed pursuant to plans and
                  specifications approved by the Landlord and in accordance with
                  all procedures applicable to said work and all other
                  provisions of this Lease. The restoration shall be commenced
                  within ninety (90) days from the date of damage or partial
                  destruction; however, the Landlord may grant such extensions
                  of time for the adjustment of

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                  insurance and the preparation of plans and specifications as
                  reasonably may be required. if the Premises as provided by the
                  Landlord shall be totally destroyed, and the Tenant has not
                  terminated this lease as provided in section 15A, then
                  construction shall commence as soon as practicable after said
                  damage or destruction. The architect or engineer in charge of
                  restoration of Tenant provided interior improvements shall be
                  selected by the Tenant and approved in writing by the
                  Landlord. The Tenant shall diligently complete the
                  restoration.

                  No partial destruction or damage to the Tenant-provided
                  interior improvements shall permit the Tenant to surrender
                  this Lease or relieve the Tenant from its obligations to pay
                  rent or from any other obligations hereunder. The Tenant
                  waives any rights now or in the future conferred upon it by
                  stature or otherwise to quit or surrender this Lease or to any
                  rebate, refund, suspension, diminution, abatement, or
                  reduction of rent on account of any partial destruction or
                  damage to the Tenant provided interior improvements.

      16. Holding Over. If the Tenant retains possession of the Premises or any
part thereof, by lapse of time or otherwise, after the termination of this
Lease, the Tenant shall pay the Landlord rent at double the rate payable for the
year immediately preceding said holdover computed on per month basis, for the
time the Tenant thus remains in possession. The provisions of this paragraph do
not waive the Landlord's rights of re-entry or any other right hereunder. Any
retention of the Premises after the termination of this lease or any extension
thereof shall be considered as a month-to-month holdover unless otherwise agreed
to in writing by both parties.

      17. Landlord's Remedies. All rights and remedies of the Landlord herein
enumerated shall be cumulative, and this Lease shall not exclude any other right
or remedy allowed herein or by law. If any provision hereof shall be held
invalid or unenforceable, the remaining provisions hereof shall continue valid,
enforceable and applicable.

            A.    If the Tenant defaults in the payment of base rent, additional
                  rent, or with regard to the payment of any other sums due
                  hereunder and if said default is not remedied within ten (10)
                  days after written demand is made by Landlord, then in any
                  such event, Landlord may, if the Landlord so elects but not
                  otherwise, either forthwith terminate this Lease and the
                  Tenant's right to possession of the Premises, or, without
                  terminating this Lease, forthwith terminate the Tenant's right
                  to

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                  possession of the Premises and the Landlord may exercise any
                  and all remedies available to it under Iowa law, including but
                  not limited to, the foreclosure of its Landlord's lien against
                  all tangible personal property excepting property that is
                  confidential or otherwise proprietary in nature such as
                  patents, copyrights, trade secrets, software programs, data,
                  and the like of the Tenant maintained within the Building.

            B.    If the Tenant defaults in the prompt and full performance of
                  any other provision of this Lease; and if such default is not
                  remedied or prompt and full performance is not accomplished by
                  Tenant or Tenant has not promptly instituted and is not
                  vigorously pursuing such remedies as are necessary to rectify
                  such default within thirty days after written demand is made
                  by Landlord, or if the Tenant abandons the Premises, then and
                  in any such event, the Landlord may, if the Landlord so elects
                  but not otherwise, forthwith terminate this Lease and the
                  Tenant's right to the Premises or without terminating this
                  Lease, forthwith terminate the Tenant's right to possession of
                  the Premises and exercise any and all other remedies available
                  to the Landlord under Iowa law, including but not limited to
                  the foreclosure of its Landlord's lien as limited above.

            C.    Upon any termination of this Lease, whether by lapse of time
                  or otherwise, or upon termination of the Tenant's right to
                  possession without termination of the Lease, the Tenant shall
                  immediately surrender possession and vacate the Premises and
                  deliver possession thereof to the Landlord, and the Tenant
                  hereby grants to the Landlord full and free license to enter
                  the Premises with or without process of law, and to repossess
                  and remove any and all property therefrom using such force as
                  may be necessary, without being deemed guilty of trespass,
                  eviction, or forcible entry or detainer, and without
                  relinquishing the Landlord's right to rent or any other right
                  given to the Landlord hereunder or by operation of law.

            D.    Any and all property which may be removed from the Premises by
                  the Landlord pursuant to the authority of the Lease or of law,
                  to which the Tenant is or may be entitled may be handled,
                  removed and stored by the Landlord at the risk, cost and
                  expense of the Tenant, provided, however, that Landlord shall
                  use reasonable care and caution to prevent any,

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                  damage or loss to such property in removing and storing such
                  property. The Tenant shall pay to the Landlord, upon demand,
                  any and all reasonable expenses incurred in such removal and
                  all reasonable storage charges against such property as long
                  as the same shall be in the Landlord's possession or under the
                  Landlord's control. Any such property of the tenant not
                  removed from the Premises or retaken from storage by the
                  Tenant within 60 days after the end of the term, however,
                  terminated, or any extension thereof, shall be conclusively
                  deemed to have been forever abandoned by the Tenant.

            E.    If Tenant is adjudicated to be bankrupt or is found insolvent
                  in any court of record, or if a receiver or trustee for the
                  benefit of Tenant's creditors is appointed, Landlord at its
                  sole option may terminate this Lease without notice and shall
                  be entitled to damages as provided by law or the terms hereof,
                  provided, however, that such adjudication, finding or
                  appointment is not set aside within 30 days or an appeal
                  therefrom shall not be prosecuted within said 30 days and said
                  appeal is either pending or is concluded with the
                  determination that Tenant is not bankrupt or insolvent.

            F.    If Tenant should default under the terms of this Lease,
                  Landlord shall be entitled to all reasonable costs, charges,
                  expenses, and attorneys' fees incurred by Landlord in
                  connection therewith.

      18. Tenant's Remedies Upon Default. If the Landlord is in default in
performing any of the terms or provisions of this Lease and the Landlord fails
to cure such default within thirty (30) days after receipt of written notice
from the Tenant stating with particularity the nature and extent of the default
(provided the nature of the default is of a character as to require more than 30
days to cure, the Landlord shall have an additional reasonable period of time to
cure such default if the Landlord has commenced to cure such default within 30
days as is diligently pursuing the remedies or steps necessary to cure or
correct such default), the Tenant shall have the following rights and remedies,
which distinct and separate:

            A.    The Tenant may cure the default, and the Landlord shall
                  reimburse the Tenant, upon demand, for all the Tenant's direct
                  costs;

            D.    The Tenant shall have the right to exercise any and all rights
                  and remedies available to it under applicable laws.

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      19.   Basic Finish. The Landlord agrees to provide Tenant "shell" Premises
which will include the following basic interior finish:

            A.    Concrete floor.

            B.    Exterior walls with finish concrete masonry unit face.

            C.    Exterior windows and doors with glazing but no interior trim.

            D.    Warehouse level ambient light (approximately 10 foot candles).

            E.    A 200 amp 3 phase panel at approximately the center of the
                  north wall of the Building with the Tenant, at its own
                  expense, extending electrical service to the Leased Premises.

            P.    Plumbing services will be stubbed to the north wall of the
                  Building with the Tenant, at its own expense, extending
                  plumbing services to the Leased Premises.

            G.    The heating, venting, and air conditioning units will be in
                  place with some main runs but no secondary runs or defusers.

            H.    Exterior landscaping and parking will be in place.

      Landlord, at its sole cost, shall provide the above and such other
improvements as are shown by the plans and specifications prepared by John Rice,
R.A. dated August 29, 1994, and by this reference made a part hereof.

      All interior improvements shall be completed by the Tenant consistent with
floor plans, specifications, and descriptions of materials provided by the
Tenant to the Landlord, and to be approved by the Landlord. The Tenant shall
provide Landlord with plans and specifications for Tenant improvements to be
approved by Landlord which improvements shall be substantially completed within
90 days from the date Landlord releases the Premises to Tenant for construction
of Tenant improvements. The Landlord agrees to advance the costs of the Tenant's
improvements in an amount not to exceed $40,000.00 and the Tenant agrees to
repay said $40,000.00 as per the attached amortization schedule with three
percent interest per annum (amortization table attached) until all sums are paid
in full. The parties agree to execute all necessary notes, security agreements,
and financing statements to provide the Landlord with security agreements, and
financing statements to provide the Landlord with security for the repayment of
said sum.

   14

                                      -14-

      20. Option to Renew. The Tenant shall have one option to renew the term of
this lease for one five-year term, which term shall commence immediately upon
the expiration of the original term of this Lease. Said extension shall be upon
the same terms and conditions contained herein, except for the rental rate
described in this paragraph. In the event the Tenant desires to exercise its
option to renew this lease, the Tenant shall notify the Landlord, in writing,
not less than 120 days prior to the expiration of the term hereof. During the
option period the rent payable shall equal the rent described above, $96,600.00
annually, adjusted by the change in the Bureau of Labor Statistics Consumer
Price Index, U.S. City Average, All Urban Consumers (C.P.I.U.) for the month
immediately preceding the end of the initial lease term from the index
(expressed as a percentage or otherwise) for the month of October 1994. If
publication of that index is terminated, a substantially equivalent successor
thereto shall be used to determine the adjustment in rent during the option
period.

      21. Environmental Matters. Tenant shall comply with all applicable
environmental rules, regulations, and laws and the Tenant shall indemnify,
defend and hold Landlord and the Iowa Research Park Corporation harmless from
and against any and all claims, judgments, damages, penalties, fines, costs,
liabilities, and losses (including reasonable attorneys' fees), arising out of
a breach of or violation of any applicable environmental laws. The Tenant shall
not cause any hazardous material, as described by state or federal law, to be
used, generated, stored, or disposed of on, about, or under or transported to or
from the Building, without first receiving the landlord's written consent, which
consent may be withheld for any reason and revoked at any time. The Tenant
acknowledges that the Landlord shall have no liability with respect to
violations of the provisions of this paragraph.

      22. Subletting and Assignment. For purposes of this paragraph, any
transfer of stock, change in equity ownership within the Tenant or any change of
the Tenant's capital structure shall constitute an assignment or subletting,
with the exception of changes resulting from public offerings and other changes
where less than 49% of the Tenant's equity ownership has been transferred. With
the exception stated above, the Tenant shall not assign or sublet this Lease or
any part of the Building without the prior written consent of the Landlord,
which consent shall not be unreasonably withheld under the following conditions:

            A.    The assignee is at least as creditworthy, based upon financial
                  statements submitted to the Landlord, as the Tenant.

            B.    The assignee shall agree to abide by all the terms and
                  conditions of this Lease.

            C.    There shall be no defaults under the terms of this Lease at
                  that time.

   15

                                      -15-

      Any assignment or subletting by the Tenant contrary to the terms hereof
shall have the effect of accelerating all sums due hereunder during the
remaining term of this Agreement, and shall constitute a default hereunder,
thereby entitling Landlord to pursue any and all remedies available to it. No
assignment or sublease shall relieve the Tenant of its obligations hereunder.

      23. Notices. All notice to be given by one party to the other party under
this Lease shall be given in written form and mailed or delivered to the
following:

            A.    To the Landlord, 1400 Highway 13 S.E., Cedar Rapids, Iowa
                  52403-9803, or to such other person at such other address
                  designated by Notice sent to Tenant and after commencement of
                  the term of the address to which rent is payable.

            B.    To the Tenant at the place set forth in the Schedule until
                  Tenant takes possession of the Building, and thereafter at the
                  Building or at such other address designated by notice to the
                  Landlord.

      Mailed notices shall be sent by United States mail, Certified or
Registered, postage prepaid. Such notice shall be deemed to have been given upon
depositing in the United States mail.

      24. Quiet Possession. So long as Tenant shall observe and perform the
covenants and agreements binding on it hereunder, Tenant shall at all times
during the term herein granted peacefully and quietly have and enjoy the
possession of the Premises without any encumbrance or hindrance by, from or
through the Landlord, its successors or assigns.

      25. Miscellaneous.

            A.    Each provision hereof shall extend to and shall, as the case
                  may require, bind and inure to the benefit of the Landlord and
                  the Tenant and their respective heirs, legal representatives
                  and successors, and assigns.

            B.    All amounts owed to the Landlord hereunder, for which the date
                  of payment is not expressly fixed herein, shall be paid within
                  thirty (30) days from the date the Landlord renders statements
                  of account therefore and shall bear interest at the rate of
                  ten (10%) per annum thereafter until paid.

            C.    Tenant shall deliver to Landlord or to its mortgagee,
                  auditors, or prospective purchaser when requested by Landlord,
                  a certificate to the effect that Landlord is not in default
                  therein, or stating specifically any exceptions thereto.
                  Failure to

   16

                                      -16-

                  give such a certificate within two (2) weeks after written
                  request shall be conclusive evidence that the Lease is in full
                  force and effect and Landlord is not in default and Tenant
                  shall be estopped from asserting any defaults known to Tenant
                  at that time.

            D.    In the event that all or a substantial portion of the Premises
                  is taken by eminent domain so that the Premises cannot be
                  reasonably used by Tenant for the purposes for which it is
                  demised, then at the option of either party the Lease may be
                  terminated, effective as of the date of the taking. In this
                  event, the entire award shall be paid to and retained by
                  Landlord excepting however, that Tenant may receive therefrom
                  any portion paid on account of its moving expenses.

MYRIAD DEVELOPERS, L.C.                     UROSURGE, INC.
an Iowa limited liability company           a corporation

By /s/ PATRICK H. MURPHY                    By [SIG]
   -------------------------------             ---------------------------------
   LANDLORD                                    TENANT



   17
                               AMORTIZATION TABLE



                                                                    
Principal:             $40,000.00      Payment                        $ 1,486.00
Term:                          28      Monthly Rate:                        0.23%
Annual Rate:                 3.00%     Tot. Interest                  $ 1,461.32
Start Date:              02/01/98      Tot. Payments                  $40,000.00




           PAYMENT                      PRINCIPAL       EXTRA        PRINCIPAL
 PMT#       DATE         INTEREST        PORTION      PRINCIPAL       BALANCE
 ----    ----------      --------       ---------     ---------      ---------
                                                       
   1       02/01/98       101.92         1,383.08                    38,616.92
   2       03/01/98        88.87         1,396.13                    37,220.79
   3       04/01/98        94.84         1,390.16                    35,830.63
   4       05/01/98        88.35         1,396.65                    34,433.98
   5       06/01/98        87.74         1,397.26                    33,036.72
   6       07/01/98        81.46         1,403.54                    31,633.18
   7       08/01/98        80.60         1,404.40                    30,228.78
   8       09/01/98        77.02         1,407.98                    28,820.80
   9       10/01/98        71.06         1,413.94                    27,406.86
  10       11/01/98        69.83         1,415.17                    25,991.69
  11       12/01/98        64.09         1,420.91                    24,570.78
  12       01/01/99        62.61         1,422.39                    23,148.39
  13       02/01/99        58.98         1,426.02                    21,722.37
  14       03/01/99        51.78         1,433.22                    20,289.15
  15       04/01/99        51.70         1,433.30                    18,855.85
  16       05/01/99        46.49         1,438.51                    17,417.34
  17       06/01/99        44.38         1,440.62                    15,976.72
  18       07/01/99        39.39         1,445.61                    14,531.11
  19       08/01/99        37.02         1,447.98                    13,083.13
  20       09/01/99        33.34         1,451.66                    11,631.47
  21       10/01/99        28.68         1,456.32                    10,175.15
  22       11/01/99        25.93         1,459.07                     8,716.08
  23       12/01/99        21.49         1,463.51                     7,252.57
  24     01/01/2000        18.48         1,466.52                     5,786.05
  25     02/01/2000        14.74         1,470.26                     4,315.79
  26     03/01/2000         9.93         1,475.07                     2,840.72
  27     04/01/2000         7.24         1,477.76                     1,362.96
  28     05/01/2000         3.36         1,362.96                         0.00