EXHIBIT 32.2



                    CERTIFICATION OF VICE PRESIDENT FINANCE


Pursuant to 18 U.S.C. Section 1350, as created by Section 906 of the
Sarbanes-Oxley Act of 2002, the undersigned officer of Spectrum
Pharmaceuticals, Inc. (the "Company"), hereby certifies, to such officer's
knowledge, that:

            (i)         the accompanying Annual Report on Form 10-K of the
Company for the year ended December 31, 2003 (the "Report") fully complies with
the requirements of Section 13(a) or Section 15(d), as applicable, of the
Securities Exchange Act of 1934, as amended; and

            (ii)        the information contained in the Report fairly presents,
in all material respects, the financial condition and results of operations of
the Company.



Dated:  March 29, 2004                         /s/ SHYAM K. KUMARIA
                                               --------------------------------
                                               Shyam K. Kumaria
                                               Vice President Finance