1 EXHIBIT 23.1 CONSENT OF ERNST & YOUNG LLP, INDEPENDENT AUDITORS We consent to the reference to our firm under the caption "Experts" in Amendment No. 1 to the Registration Statement (Form S-3 No. 333-16371) and related Prospectus of DepoTech Corporation for the registration of 1,500,000 shares of its common stock and to the incorporation by reference therein of our report dated February 16 1996, with respect to the financial statements of DepoTech Corporation included in its Annual Report (Form 10-K) for the year ended December 31, 1995, filed with the Securities and Exchange Commission. ERNST & YOUNG LLP San Diego, California December 26, 1996