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                                                                    EXHIBIT 10.2
[BofA LOGO]
BANK OF AMERICA                                          BUSINESS LOAN AGREEMENT
NATIONAL TRUST AND SAVINGS ASSOCIATION

This Agreement dated as of June 9, ,1998 is between Bank of America National
Trust and Savings Association (the "Bank") and CHROMAVISION MEDICAL SYSTEMS,
INC. (the "Borrower").

1. LINE OF CREDIT AMOUNT AND TERMS.

1.1 LINE OF CREDIT AMOUNT.

(a)      During the availability period described below, the Bank will provide a
         line of credit to the Borrower. The amount of the line of credit (the
         "Commitment") is Five Million Dollars ($5,000,000).

(b)      This is a revolving line of credit. During the availability period, the
         Borrower may repay principal amounts and reborrow them.

(c)      The Borrower agrees not to permit the outstanding principal balance of
         the line of credit to exceed the Commitment.

1.2 AVAILABILITY PERIOD. The line of credit is available between the date of
this Agreement and May 30, 2000 (the "Expiration Date") unless the Borrower is
in default.

1.3 INTEREST RATE.

(a)      Unless the Borrower elects an optional interest rate as described
         below, the interest rate is the Bank's Reference Rate minus one quarter
         of one (.25) percentage point.

(b)      The Reference Rate is the rate of interest publicly announced from time
         to time by the Bank in San Francisco, California, as its Reference
         Rate. The Reference Rate is set by the Bank based on various factors,
         including the Bank's costs and desired return, general economic
         conditions and other factors, and is used as a reference point for
         pricing some loans. The Bank may price loans to its customers at,
         above, or below the Reference Rate. Any change in the Reference Rate
         will take effect at the opening of business on the day specified in the
         public announcement of a change in the Bank's Reference Rate.

1.4 REPAYMENT TERMS.

(a)      The Borrower will pay interest on April 1, 1998, and then monthly
         thereafter until payment in full of any principal outstanding under
         this line of credit.

(b)      The Borrower will repay in full all principal and any unpaid interest
         or other charges outstanding under this line of credit no later than
         the Expiration Date.

(c)      Any interest period for an optional interest rate (as described below)
         shall expire no later than the Expiration Date.

1.5 OPTIONAL INTEREST RATES. Instead of the interest rate based on the Bank's
Reference Rate, the Borrower may elect the optional interest rates listed below
during interest periods agreed to by the Bank and the Borrower. The optional
interest rates shall be subject to the terms and conditions described later in
this Agreement. Any principal amount bearing interest at an optional rate under
this Agreement is referred to as a "Portion." The following optional interest
rates are available:

(a)      the Short Term Base Rate plus 1.50 percentage points.

(b)      the LIBOR Rate plus 1.50 percentage points.

2. OPTIONAL INTEREST RATES.

2.1 OPTIONAL RATES. Each optional interest rate is a rate per year. Interest
will be paid on the last day of each interest period, and on the first day of
each month during the interest period. At the end of any interest period, the
interest rate will revert to the rate based on the Reference Rate, unless the
Borrower has designated another optional interest rate for the Portion. No
Portion will be converted to a different interest rate during the applicable
interest period. Upon the occurrence of an event of default under this
Agreement, the Bank may terminate the availability of optional interest rates
for interest periods commencing after the default occurs.

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2.2 SHORT TERM BASE RATE. The election of Short Term Fixed Rates shall be
subject to the following terms and requirements:

(a)      The "Short Term Fixed Rate" means the fixed interest rate the Bank and
         the Borrower agree will apply during the applicable interest period.

(b)      The "Short Term Base Rate" means the fixed interest rate per annum,
         determined solely by the Bank on the first day of the applicable
         interest period for the Portion, as the rate at which the Bank would be
         able to borrow funds in the Money Market in the amount of the Short
         Term Fixed Rate Portion and with an interest and principal payment
         schedule equal to the Short Term Fixed Rate Portion and for a term
         equal to the applicable interest period. The Short Term Base Rate shall
         include adjustments for reserve requirements, federal deposit
         insurance, and any other similar adjustment which the Bank deems
         appropriate. The Short Term Base Rate is the Bank's estimate only and
         the Bank is under no obligation to actually purchase or match funds for
         any transaction.

(c)      "Money Market" means one or more wholesale funding markets available to
         the Bank, including domestic negotiable certificates of deposit,
         eurodollar deposits, bank deposit notes or other appropriate money
         market instruments selected by the Bank.

(d)      The interest period during which the Short Term Fixed Rate will be in
         effect will be no shorter than 30 days and no longer than one year.

(e)      Each Short Term Fixed Rate Portion may be for any dollar amount.

(f)      Each prepayment of a Short Term Fixed Rate Portion, whether voluntary,
         by reason of acceleration or otherwise, will be accompanied by the
         amount of accrued interest on the amount prepaid, and a prepayment fee
         as described below. A "prepayment" is a payment of an amount on a date
         earlier than the scheduled payment date for such amount as required by
         this Agreement. The prepayment fee shall be equal to the amount (if
         any) by which:

         (i)      the additional interest which would have been payable during
                  the interest period on the amount prepaid had it not been
                  prepaid, exceeds

         (ii)     the interest which would have been recoverable by the Bank by
                  placing the amount prepaid on deposit in the Money Market for
                  a period starting on the date on which it was prepaid and
                  ending on the last day of the interest period for such Portion
                  (or the scheduled payment date for the amount prepaid, if
                  earlier).

2.3 LIBOR RATE. The election of LIBOR Rates shall be subject to the following
terms and requirements:

(a)      The interest period during which the LIBOR Rate will be in effect will
         be one, two, three, four, five, six, seven, eight, nine, ten, eleven,
         or twelve months. The first day of the interest period must be a day
         other than a Saturday or a Sunday on which the Bank is open for
         business in California, New York and London and dealing in offshore
         dollar (a "LIBOR Banking Day"). The last day of the interest period and
         the actual number of days during the interest period will be determined
         by the Bank using the practices of the London inter-bank market.

(b)      Each LIBOR Rate Portion may be for any dollar amount.

(c)      The "LIBOR Rate" means the interest rate determined by the following
         formula rounded upward to the nearest 1/100 of one percent. (All
         amounts in the calculation will be determined by the Bank as of the
         first day of the interest period.)

                 LIBOR Rate =     London Inter-Bank Offered Rate
                                  ------------------------------
                                  (1 .00 - Reserve Percentage)

         Where,

         (i)      "London Inter-Bank Offered Rate" means the interest rate at
                  which the Bank's London Branch, London, Great Britain, would
                  offer U.S. dollar deposits for the applicable interest period
                  to other major banks in the London inter-bank market at
                  approximately 11:00 a.m. London time two (2) London Banking
                  Days before the commencement of the interest period. A "London
                  Banking Day" is a day on which the Bank's London Branch is
                  open for business and dealing in offshore dollars.

         (ii)     "Reserve Percentage" means the total of the maximum reserve
                  percentages for determining the reserves to be maintained by
                  member banks of the Federal Reserve System for Eurocurrency
                  Liabilities, as defined in Federal Reserve Board Regulation D,
                  rounded upward to the nearest 1/100 of one percent. The
                  percentage will be


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                  expressed as a decimal, and will include, but not be limited
                  to, marginal, emergency, supplemental, special, and other
                  reserve percentages.

(d)      The Borrower shall irrevocably request a LIBOR Rate Portion no later
         than 12:00 noon San Francisco time on the LIBOR Banking Day preceding
         the day on which the London Inter-Bank Offered Rate will be set, as
         specified above. For example, if there are no intervening holidays or
         weekend days in any of the relevant locations, the request must be made
         at least three days before the LIBOR Rate takes effect.

(e)      The Borrower may not elect a LIBOR Rate with respect to any principal
         amount which is scheduled to be repaid before the last day of the
         applicable interest period.

(f)      Each prepayment of a LIBOR Rate Portion, whether voluntary, by reason
         of acceleration or otherwise, will be accompanied by the amount of
         accrued interest on the amount prepaid and a prepayment fee as
         described below. A "prepayment" is a payment of an amount on a date
         earlier than the scheduled payment date for such amount as required by
         this Agreement. The prepayment fee shall be equal to the amount (if
         any) by which:

         (i)      the additional interest which would have been payable during
                  the interest period on the amount prepaid had it not been
                  prepaid, exceeds

         (ii)     the interest which would have been recoverable by the Bank by
                  placing the amount prepaid on deposit in the domestic
                  certificate of deposit market, the eurodollar deposit market,
                  or other appropriate money market selected by the Bank, for a
                  period starting on the date on which it was prepaid and ending
                  on the last day of the interest period for such Portion (or
                  the scheduled payment date for the amount prepaid, if
                  earlier).

(g)      The Bank will have no obligation to accept an election for a LIBOR Rate
         Portion if any of the following described events has occurred and is
         continuing:

         (i)      Dollar deposits in the principal amount, and for periods equal
                  to the interest period, of a LIBOR Rate PorlJon are not
                  available in the London inter-bank market; or

         (ii)     the LIBOR Rate does not accurately reflect the cost of a LIBOR
                  Rate Portion.

3. EXPENSES

3.1 REIMBURSEMENT COSTS.

(a)      The Borrower agrees to reimburse the Bank for any expenses it incurs in
         the preparation of this Agreement and any agreement or instrument
         required by this Agreement. Expenses include, but are not limited to,
         reasonable attorneys' fees, including any allocated costs of the Bank's
         in-house counsel.

(b)      The Borrower agrees to reimburse the Bank for the cost of periodic
         audits of the collateral securing this Agreement, at such intervals as
         the Bank may reasonably require. The audits may be performed by
         employees of the Bank or by independent auditors.

4. PERSONAL PROPERTY COLLATERAL. The Borrower's obligations to the Bank under
this Agreement will be secured by personal property the Borrower now owns or
will own in the future as listed below. The collateral is further defined in
security agreement(s) executed by the Borrower.

(a)      Securities account number 01-40-403-0010320 (the "Account") owned by
         the Borrower and maintained by the Bank. The contents of the Account
         are subject to restrictions imposed by this and other agreements
         between the Bank and the Borrower. Regulation U of the Board of
         Governors of the Federal Reserve System places certain restrictions on
         loans secured by margin stock (as defined in the Regulation). The Bank
         and the Borrower shall comply with Regulation U. If any of the
         collateral is margin stock, the Borrower shall provide to the Bank a
         Form U-1 Purpose Statement. The Bank is prohibited from accepting as
         collateral certain Ineligible Securities while they are being
         underwritten or privately placed by BankAmerica Robertson Stephens
         ("BRS"). The Bank and the Borrower shall comply with these
         restrictions. BRS is a wholly-owned subsidiary of BankAmerica
         Corporation, and is a registered broker-dealer which is permitted to
         underwrite and deal in certain Ineligible Securities. "Ineligible
         Securities" means securities which may not be underwritten or dealt in
         by member banks of the Federal Reserve System under Section 16 of the
         Banking Act of 1933 (12 U.S.C. Section 24, Seventh), as amended.


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5. DISBURSEMENTS, PAYMENTS AND COSTS.

5.1 TELEPHONE AND TELEFAX AUTHORIZATION.

(a)      The Bank may honor telephone or telefax instructions for advances or
         repayments or for the designation of optional interest rates given by
         any one of the individuals authorized to sign loan agreements on behalf
         of the Borrower, or any other individual designated by any one of such
         authorized signers.

(b)      Advances will be deposited in and repayments will be withdrawn from the
         Borrower's account number 14178-03031, or such other of the Borrower's
         accounts with the Bank as designated in writing by the Borrower.

(c)      The Borrower indemnifies and excuses the Bank (including its officers,
         employees, and agents) from all liability, loss, and costs in
         connection with any act resulting from telephone or telefax
         instructions it reasonably believes are made by any individual
         authorized by the Borrower to give such instructions. This indemnity
         and excuse will survive this Agreement's termination.

5.2 DIRECT DEBIT. The Borrower agrees that interest and principal payments and
any fees will be deducted automatically on the due date from the Borrower's
account number 14178-03031, or such other of the Borrower's accounts with the
Bank as designated in writing by the Borrower. If there are insufficient funds
in the account on the date the Bank enters any debit authorized by this
Agreement, the debit will be reversed.

5.3 BANKING DAYS. Unless otherwise provided in this Agreement, a banking day is
a day other than a Saturday or a Sunday on which the Bank is open for business
in California. All payments and disbursements which would be due on a day which
is not a banking day will be due on the next banking day. All payments received
on a day which is not a banking day will be applied to the credit on the next
banking day.

5.4 ADDITIONAL COSTS. The Borrower will pay the Bank, on demand, for the Bank's
costs or losses arising from any statute or regulation, or any request or
requirement of a regulatory agency which is applicable to all national banks or
a class of all national banks. The costs and losses will be allocated to the
loan in a manner determined by the Bank, using any reasonable method. The costs
include the following: (a) any reserve or deposit requirements; and (b) any
capital requirements relating to the Bank's assets and commitments for credit.

5.5 INTEREST CALCULATION. Except as otherwise stated in this Agreement, all
interest and fees, if any, will be computed on the basis of a 360-day year and
the actual number of days elapsed. This results in more interest or a higher fee
than if a 365-day year is used. Instalments of principal which are not paid when
due under this Agreement shall continue to bear interest until paid.

5.6 DEFAULT RATE. Upon the occurrence and during the continuation of any default
under this Agreement, principal amounts outstanding under this Agreement will at
the option of the Bank bear interest at s rate which is two (2.00) percentage
points higher than the rate of interest otherwise provided under this Agreement.
This will not constitute a waiver of any default.


6. CONDITIONS. The Bank must receive any documents and other items it may
reasonably require, including but not limited to the following items, in form
and content acceptable to the Bank, before it is required to extend any credit
to the Borrower under this Agreement.

6.1 AUTHORIZATIONS. Evidence that the execution, delivery and performance by the
Borrower and each guarantor of this Agreement and any instrument or agreement
required under this Agreement have been duly authorized.

6.2 GOVERNING DOCUMENTS. A copy of the Borrower's articles of incorporation.

6.3 SECURITY AGREEMENTS. Signed original security agreements, assignments,
financing statements and fixture filings (together with collateral in which the
Bank requires a possessory security interest), and deeds of trust which the Bank
requires.

6.4 EVIDENCE OF PRIORITY. Evidence that security interests and liens in favor of
the Bank are valid, enforceable, and prior to all others' rights and interests,
except those the Bank consents to in writing.

6.5 CONDITIONS TO EACH ADVANCE. As additional prior conditions to the Bank's
obligation to make any advance under the line of credit, and notwithstanding any
provision to the contrary herein, Borrower shall have deposited into the Account
such additional Permitted Assets as are necessary to raise the market value of
the Account to at least one hundred eleven percent (111%) of the



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aggregate amount of all outstandings under the line of credit after giving
effect to the requested advance, and Bank shall have received from Short Term
Asset Management's ("STAM") facsimile or written confirmation (or such other
evidence as is satisfactory to Bank in its sole discretion) that the market
value of the Account meets such requirement.

7. REPRESENTATIONS AND WARRANTIES. When the Borrower signs this Agreement, and
until the Bank is repaid in full, the Borrower makes the following
representations and warranties. Each request for an extension of credit
constitutes a renewed representation:

7.1 ORGANIZATION OF BORROWER. The Borrower is a corporation duly formed and
existing under the laws of the state where organized.

7.2 AUTHORIZATION. This Agreement has been duly authorized and is enforceable
without conflict with any laws or any other obligation of the Borrower.

7.3 GOOD STANDING. In each state in which the Borrower does business, it is
properly licensed, in good standing, and, where required, in compliance with
fictitious name statutes.

7.4 LAWSUITS. There is no lawsuit, tax claim or other dispute pending or
threatened against the Borrower, which, if lost, would impair the Borrower's
financial condition or ability to repay the loan, except as have been disclosed
in writing to the Bank.

7.5 PERMITS, FRANCHISES. The Borrower possesses all permits, memberships,
franchises, contracts and licenses required and all trademark rights, trade name
rights, patent rights and fictitious name rights necessary to enable it to
conduct the business in which it is now engaged.

7.6 LOCATION OF BORROWER. The Borrower's place of business (or, if the Borrower
has more than one place of business, its chief executive office) is located at
the address listed under the Borrower's signature on this Agreement.

7.7 COLLATERAL ACCOUNT.

(a)      The Account consists solely of interests in the following:

         (i)      Liquidity Optimized General Investment Contracts established
                  with major insurance companies with quality ratings of at
                  least Al/P1 ("Acceptable LOGICs"); and

         (ii)     LateCash Bank Issues in Banks with quality ratings of at least
                  Al/P1 ("Acceptable LateCash").

(b)      The market value of the assets in the Account shall at all times be not
         less than one hundred eleven percent (111%) of the aggregate amount of
         all outstandings under the line of credit.

7.8 YEAR 2000 COMPLIANCE. The Borrower has implemented a comprehensive program
to address the "year 2000 problem" (that is, the risk that computer applications
may not be able to properly perform date-sensitive functions after December 31,
1999) and expects to resolve on a timely basis any material year 2000 problem.
The Borrower has also made inquiry of each supplier, vendor and customer of the
Borrower that is of material importance to the financial well-being of the
Borrower with respect to the "year 2000 problem". On the basis of that inquiry,
the Borrower believes that each such supplier, vendor and customer of the
Borrower will resolve any material year 2000 problem on a timely basis.

8. COVENANTS. The Borrower agrees, so long as credit is available under this
Agreement and until the Bank is repaid in full:

8.1 USE OF PROCEEDS. To use the proceeds of the credit only to bridge maturing
investment and cash flow requirements.

8.2 FINANCIAL INFORMATION. To provide the following financial information and
statements in form and content acceptable to the Bank, and such additional
information as requested by the Bank from time to time:

(a)      Within 90 days of the Borrower's fiscal year end, the Borrower's annual
         financial statements. These financial statements must be audited (with
         an opinion satisfactory to the Bank) by a certified public accountant
         ("CPA") acceptable to the Bank.

(b)      Within 60 days of the period's end, the Borrower's quarterly financial
         statements. These financial statements may be Borrower prepared.

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(c)      Within 30 days of each month end, the Borrower shall provide to the
         Bank copies of statements from STAM evidencing collateral with a value
         of at least one hundred eleven percent (111%) of the amount of all
         aggregate outstandings under the line of credit.

8.3 OTHER DEBTS. Not to have outstanding or incur any direct or contingent
liabilities (other than those to the Bank), or become liable for the liabilities
of others without the Bank's written consent. This does not prohibit:

(a)      Acquiring goods, supplies, or merchandise on normal trade credit.

(b)      Endorsing negotiable instruments received in the usual course of
         business.

(c)      Obtaining surety bonds in the usual course of business.

(d)      Liabilities in existence on the date of this Agreement disclosed in
         writing to the Bank in the Borrower's financial statement dated
         December 31, 1997.

(e)      Additional credit for a Three Million Dollar ($3,000,000) asset based
         line of credit.

8.4 OTHER LIENS. Not to create, assume, or allow any security interest or lien
(including judicial liens) on property the Borrower now or later owns, except:

(a)      Deeds of trust and security agreements in favor of the Bank.

(b)      Liens for taxes not yet due.

(c)      Liens to support line of credit as stated in paragraph 8.3(e) of this
         Agreement.

8.5 OUT OF DEBT PERIOD. To repay any advances in full, and not to draw any
additional advances on its revolving line of credit, for a period of at least
one (1) day in each fiscal quarter.

8.6 NOTICES TO BANK. To promptly notify the Bank in writing of:

(a)      any lawsuit over One Million Dollars ($1 ,O00,000) against the Borrower
         or any guarantor (or any trustor).

(b)      any substantial dispute between the Borrower or any guarantor (or any
         trustor) and any government authority.

(c)      any failure to comply with this Agreement.

(d)      any material adverse change in the Borrower's or any guarantor's (or
         any trustor's) business condition (financial or otherwise), operations,
         properties or prospects, or ability to repay the credit.

(e)      any change in the Borrower's name, legal structure, place of business,
         or chief executive office if the Borrower has more than one place of
         business.

8.7 AUDITS. To allow the Bank and its agents to examine, audit, and make copies
of any physical certificates and books and records concerning the collateral
securing this Agreement at any reasonable time. If any of the collateral, books,
or records are in the possession of a third party, the Borrower authorizes that
third party to permit the Bank or its agents to have access to perform
examinations or audits.

8.8 COMPLIANCE WITH LAWS. To comply with the laws (including any fictitious name
statute), regulations, and orders of any government body with authority over the
Borrower's business.

8.9 PERFECTION OF LIENS. To help the Bank perfect and protect its security
interests and liens, and reimburse it for related costs it incurs to protect its
security interests and liens.

8.10 INSURANCE. To maintain insurance as is usual for the business it is in.

8,11 ADDITIONAL NEGATIVE COVENANTS. Not to, without the Bank's written consent:

(a)      engage in any business activities substantially different from the
         Borrower's present business, 

(b)      liquidate or dissolve the Borrower's business.



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(c)      enter into any consolidation, merger, or other combination, or become a
         partner in a partnership, a member of a joint venture, or a member of a
         limited liability company, with the exception of the joint venture with
         Chiron Diagnostic, Inc.

(d)      sell, assign, lease, transfer or otherwise dispose of any assets for
         less than fair market value, or enter into any agreement to do so.

(e)      sell, assign, lease, transfer or otherwise dispose of all or a
         substantial part of the Borrower's business or the Borrower's assets.

(f)      enter into any sale and leaseback agreement covering any of its fixed
         or capital assets, with the exception of what is permitted under
         Paragraph 8.3(e) of this Agreement.

(g)      acquire or purchase a business or its assets

(h)      voluntarily suspend its business for more than one day (except for
         weekends and state or federal holidays).

(i)      acquire master notes or variable amount notes.

(j)      deposit, or direct or instruct BTAM or any other person to deposit, any
         assets into the Account other than Acceptable LOGICs and/or Acceptable
         LateCash (collectively, "Permitted Assets").

(k)      direct or instruct any other person to acquire for the Account, any
         master notes or variable amount notes.

8.12 VALUE OF COLLATERAL ACCOUNT. To maintain Permitted Assets in the Account
with a market value of not less than one hundred eleven percent (111%) of the
amount of all aggregate outstandings under the line of credit, and to
immediately add to the Account, as required to increase the market value of the
Account to at least 111% of the amount of all aggregate outstandings.

9. DEFAULT. If any of the following events occur, the Bank may do one or more of
the following: declare the Borrower in default, stop making any additional
credit available to the Borrower, and require the Borrower to repay its entire
debt immediately and without prior notice. If a bankruptcy petition is filed
with respect to the Borrower, the entire debt outstanding under this Agreement
will automatically become due immediately.

9.1 FAILURE TO PAY. The Borrower fails to make a payment under this Agreement
when due.

9.2 LIEN PRIORITY. The Bank fails to have an enforceable first lien (except for
any prior liens to which the Bank has consented in writing) on or security
interest in any property given as security for this Agreement (or any guaranty).

9.3 FALSE INFORMATION. The Borrower or any guarantor (or any trustor) has given
the Bank false or misleading information or representations.

9.4 BANKRUPTCY, RECEIVERS. The Borrower or any guarantor (or any trustor) or any
general partner of the Borrower files a bankruptcy petition, a bankruptcy
petition is filed against the Borrower or any guarantor (or any trustor) or any
general partner of the Borrower or the Borrower or any guarantor (or any
trustor) or any general partner of the Borrower makes a general assignment for
the benefit of creditors; or a receiver or similar official is appointed for the
Borrower's or any guarantor's (or any trustor's) business, or the business is
terminated or any guarantor is liquidated or dissolved.

9.5 LAWSUITS. Any lawsuit or lawsuits are filed against the Borrower or any
guarantor (or any trustor) in an aggregate amount of One Million Dollars
($1,000,000) or more in excess of any insurance coverage.

9.6 JUDGMENTS. Any judgments or arbitration awards are entered against the
Borrower or any guarantor (or any trustor), or the Borrower or any guarantor (or
any trustor) enters into any settlement agreements with respect to any
litigation or arbitration, in an aggregate amount of Five Hundred Thousand
Dollars ($500,000) or more in excess of any insurance coverage.

9.7 GOVERNMENT ACTION. Any government authority takes action that the Bank
believes materially adversely affects the Borrower's or any guarantor's (or any
trustor's) financial condition or ability to repay.

9.8 MATERIAL ADVERSE CHANGE. A material adverse change occurs, or is reasonably
likely to occur in the Borrower's or any guarantor's (or any trustor's) business
condition (financial or otherwise), operations, properties or prospects, or
ability to repay the credit.


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9.9 CROSS-DEFAULT. Any material default occurs under any agreement in connection
with any credit the Borrower or any guarantor (or any trustor) or any of the
Borrower's related entities or affiliates has obtained from anyone else or which
the Borrower or any guarantor (or any trustor) or any of the Borrower's related
entities or affiliates has guaranteed. If, in the Bank's opinion, the breach is
capable of being remedied, the breach will not be considered an event of default
under this Agreement for a period of 15 days after the date on which the Bank
gives written notice of the breach to the Borrower; provided, however, that the
Bank will not be obligated to extend any additional credit to the Borrower
during that period.

9.10 DEFAULT UNDER RELATED DOCUMENTS. Any guaranty, subordination agreement,
security agreement, deed of trust, or other document required by this Agreement
is violated or no longer in effect.

9.11 OTHER BANK AGREEMENTS. The Borrower or any guarantor (or any trustor) fails
to meet the conditions of, or fails to perform any obligation under any other
agreement the Borrower or any guarantor (or any trustor) has with the Bank or
any affiliate of the Bank.

9.12 OTHER BREACH UNDER AGREEMENT. The Borrower fails to meet the conditions of,
or fails to perform any obligation under, any term of this Agreement not
specifically referred to in this Article. This includes any failure or
anticipated failure by the Borrower to comply ~ any financial covenants set
forth in this Agreement, whether such failure is evidenced by financial
statements delivered to the Bank or is otherwise known to the Borrower or the
Bank.

10. ENFORCING THIS AGREEMENT; MISCELLANEOUS.

10.1 GAAP. Except as otherwise stated in this Agreement, all financial
information provided to the Bank and all financial covenants will be made under
generally accepted accounting principles, consistently applied.

10.2 CALIFORNIA LAW. This Agreement is governed by California law.

10.3 SUCCESSORS AND ASSIGNS. This Agreement is binding on the Borrower's and the
Bank's successors and assignees. The Borrower agrees that it may not assign this
Agreement without the Bank's prior consent.

10.4 ARBITRATION.

(a)      This paragraph concerns the resolution of any controversies or claims
         between the Borrower and the Bank, including but not limited to those
         that arise from:

         (i)      This Agreement (including any renewals, extensions or
                  modifications of this Agreement);

         (ii)     Any document, agreement or procedure related to or delivered
                  in connection with this Agreement;


         (iii)    Any violation of this Agreement; or

         (iv)     Any claims for damages resulting from any business conducted
                  between the Borrower and the Bank, including claims for injury
                  to persons, property or business interests (torts).

(b)      At the request of the Borrower or the Bank, any such controversies or
         claims will be settled by arbitration in accordance with the United
         States Arbitration Act. The United States Arbitration Act will apply
         even though this Agreement provides that it is governed by California
         law.

(c)      Arbitration proceedings will be administered by the American
         Arbitration Association and will be subject to its commercial rules of
         arbitration.

(d)      For purposes of the application of the statute of limitations, the
         filing of an arbitration pursuant to this paragraph is the equivalent
         of the filing of a lawsuit, and any claim or controversy which may be
         arbitrated under this paragraph is subject to any applicable statute of
         limitations. The arbitrators will have the authority to decide whether
         any such claim or controversy is barred by the statute of limitations
         and, if so, to dismiss the arbitration on that basis.

(e)      If there is a dispute as to whether an issue is arbitrable, the
         arbitrators will have the authority to resolve any such dispute.

(f)      The decision that results from an arbitration proceeding may be
         submitted to any authorized court of law to be confirmed and enforced.


                                      -8-

   9


(g)      The procedure described above will not apply if the controversy or
         claim, at the time of the proposed submission to arbitration, arises
         from or relates to an obligation to the Bank secured by real property
         located in California. In this case, both the Borrower and the Bank
         must consent to submission of the claim or controversy to arbitration.
         If both parties do not consent to arbitration, the controversy or claim
         will be settled as follows:

         (i)      The Borrower and the Bank will designate a referee (or a panel
                  of referees) selected under the auspices of the American
                  Arbitration Association in the same manner as arbitrators are
                  selected in Association-sponsored proceedings;

         (ii)     The designated referee (or the panel of referees) will be
                  appointed by a court as provided in California Code of Civil
                  Procedure Section 638 and the following related sections;

         (iii)    The referee (or the presiding referee of the panel) will be an
                  active attorney or a retired judge; and

         (iv)     The award that results from the decision of the referee (or
                  the panel) will be entered as a judgment in the court that
                  appointed the referee, in accordance with the provisions of
                  California Code of Civil Procedure Sections 644 and 645.

(h)      This provision does not limit the right of the Borrower or the Bank to:

         (i)      exercise self-help remedies such as setoff;

         (ii)     foreclose against or sell any real or personal property
                  collateral; or

         (iii)    act in a court of law, before, during or after the arbitration
                  proceeding to obtain:

                  (A)      an interim remedy; and/or

                  (B)      additional or supplementary remedies.

(i)      The pursuit of or a successful action for interim, additional or
         supplementary remedies, or the filing of a court action, does not
         constitute a waiver of the right of the Borrower or the Bank, including
         the suing party, to submit the controversy or claim to arbitration if
         the other party contests the lawsuit. However, if the controversy or
         claim arises from or relates to an obligation to the Bank which is
         secured by real property located in California at the time of the
         proposed submission to arbitration, this right is limited according to
         the provision above requiring the consent of both the Borrower and the
         Bank to seek resolution through arbitration.

(j)      If the Bank forecloses against any real property securing this
         Agreement, the Bank has the option to exercise the power of sale under
         the deed of trust or mortgage, or to proceed by judicial foreclosure.

10.5 SEVERABILITY; WAIVERS. If any part of this Agreement is not enforceable,
the rest of the Agreement may be enforced. The Bank retains all rights, even if
it makes a loan after default. If the Bank waives a default, it may enforce a
later default. Any consent or waiver under this Agreement must be in writing.

10.6 ATTORNEYS' FEES. The Borrower shall reimburse the Bank for any reasonable
costs and attorneys' fees incurred by the Bank in connection with the
enforcement or preservation of any rights or remedies under this Agreement and
any other documents executed in connection with this Agreement, and in
connection with any amendment, waiver, "workout" or restructuring under this
Agreement. In the event of a lawsuit or arbitration proceeding, the prevailing
party is entitled to recover costs and reasonable attorneys' fees incurred in
connection with the lawsuit or arbitration proceeding, as determined by the
court or arbitrator. In the event that any case is commenced by or against the
Borrower under the Bankruptcy Code (Title 11, United States Code) or any similar
or successor statute, the Bank is entitled to recover costs and reasonable
attorneys' fees incurred by the Bank related to the preservation, protection, or
enforcement of any rights of the Bank in such a case. As used in this paragraph,
"attorneys' fees" includes the allocated costs of the Bank's in-house counsel.

10,7 ONE AGREEMENT. This Agreement and any related security or other agreements
required by this Agreement, collectively:

(a)      represent the sum of the understandings and agreements between the Bank
         and the Borrower concerning this credit;

(b)      replace any prior oral or written agreements between the Bank and the
         Borrower concerning this credit; and

(c)      are intended by the Bank and the Borrower as the final, complete and
         exclusive statement of the terms agreed to by them.

                                      -9-

   10




In the event of any conflict between this Agreement and any other agreements
required by this Agreement, this Agreement will prevail.

10.8 INDEMNIFICATION. The Borrower will indemnify and hold the Bank harmless
from any loss, liability, damages, judgments, and costs of any kind relating to
or arising directly or indirectly out of

(a)      this Agreement or any document required hereunder,

(b)      any credit extended or committed by the Bank to the Borrower hereunder,
         and

(c)      any litigation or proceeding related to or arising out of this
         Agreement, any such document, or any such credit. This indemnity
         includes but is not limited to attorneys' fees (including the allocated
         cost of in-house counsel).

This indemnity extends to the Bank, its parent, subsidiaries and all of their
directors, officers, employees, agents, successors, attorneys, and assigns. This
indemnity will survive repayment of the Borrower's obligations to the Bank. All
sums due to the Bank hereunder shall be obligations of the Borrower, due and
payable immediately without demand.

This Agreement is executed as of the date stated at the top of the first page.



BANK OF AMERICA NATIONAL TRUST AND SAVINGS    CHROMAVISION MEDICAL SYSTEMS, INC.
ASSOCIATION

By /s/ BETSY BACKAM                           By /s/ DOUG HARRINGTON
   -------------------------------------         -------------------------------
Name: Betsy Backam                            Name: Doug Harrington
Title: Vice President                         Title: Chief Executive Officer
                                              

                                              By /s/ KEVIN O'BOYLE  
                                                 -------------------------------
                                              Name: Kevin O'Boyle
                                              Title: Vice President and     
                                                     Chief Financial Officer


Address where notices to Bank                  Address where notices to Borrower
are to be sent:                                are to be sent:

Century city regional Commercial Banking
  Office 01417                                 ---------------------------------
2049 Century Park East, Suite 200              33171  Paseo Cerveza
Los Angeles, California 90067                  San Juan Capistrano, California
                                               92675


                                      -10-

   11
[B of A LOGO]
Bank of America
National Trust and Savings Association

                               SECURITY AGREEMENT
                                  (Securities)

1. Grant of Security interest. As security for any and all Indebtedness (as
defined below) of ChromaVision Medical Systems, Inc. ("Debtor"), the undersigned
ChromaVision Medical Systems, Inc. ("Pledgor") hereby irrevocably and
unconditionally grants a security interest in and assigns and transfers to Bank
of America National Trust and Savings Association ("Bank") all property referred
to in Exhibit A attached hereto (the "Collateral").

2. Indebtedness. "Indebtedness" means all debts, obligations or liabilities now
or hereafter existing, absolute or contingent of Debtor or any one or more of
them to Bank, whether voluntary or involuntary, whether due or not due, or
whether incurred directly or indirectly or acquired by Bank by assignment or
otherwise. Unless otherwise agreed in writing, "indebtedness" shall not include
such debts, obligations or liabilities which are or may hereafter be "consumer
credit" subject to the disclosure requirements of the Federal Truth-in-Lending
law or any regulation promulgated thereunder.

3. Pledgor's Covenants. Pledgor covenants and warrants that unless compliance is
waived by Bank in writing:

(a) Pledgor owns the Collateral free and clear of any and all liens,
    encumbrances, or interests of any third parties other than the security
    interest of Bank, and will keep the Collateral free of all liens, claims,
    security interests and encumbrances of any kind or nature except the
    security interest of Bank.

(b) Pledgor will at all times maintain Collateral of a character and value
    satisfactory to Bank.

(c) Pledgor shall take all actions necessary from time to time to maintain the
    first priority and perfection of said security interest and shall not take
    any actions that would alter, impair or eliminate said priority or
    perfection.

(d) Pledgor agrees to pay prior to delinquency all taxes, charges, liens and
    assessments against the Collateral, and upon the failure of Pledgor to do
    so, Bank at its option may pay any of them and shall be the sole judge of
    the legality or validity thereof and the amount necessary to discharge the
    same.

(e) Pledgor will notify Bank in writing prior to any change in Pledgor's name,
    identity or business structure.

(f) Pledgor resides (if Pledgor is an individual), or Pledgor's chief executive
    office (if Pledgor is not an individual) is located, in the state specified
    on the signature page hereof. Pledgor shall give Bank at least thirty (30)
    days' notice before changing said state of residence or of its chief
    executive office.

4. Powers of Bank. At any time, without notice, and at the expense of Pledgor
and Debtor, Bank in its name or in the name of Pledgor may, but shall not be
obligated to:

(a) Collect by legal proceedings or otherwise, endorse, receive and receipt for
    all dividends, interest, principal payments and other sums now or hereafter
    payable upon or on account of the Collateral.

(b) Make any compromise or settlement it deems desirable or proper with
    reference to the Collateral.

(c) Insure, process and preserve the Collateral.

(d) Participate in any recapitalization, reclassification, reorganization,
    consolidation, redemption, stock split, merger or liquidation of any issuer
    of securities which constitute Collateral, and in connection therewith may
    deposit or surrender control of the Collateral, accept money or other
    property in exchange for the Collateral, and take such action as it deems
    proper in connection therewith, and any money or property received on
    account of or in exchange for the Collateral shall be applied to the
    Indebtedness or held by Bank thereafter as Collateral pursuant to the
    provisions hereof.

(e) Cause Collateral to be transferred to its name or to the name of its nominee
    or the name of a depository or its nominee.


                                      -1-
   12

(f) Obtain from any custodian or bailee holding the Collateral any and all
    information with respect to the Collateral, without any further consent of
    or notice to Pledgor.

(g) Exercise as to the Collateral all the rights, powers and remedies of an
    owner necessary to exercise its rights under this paragraph, but prior to
    any Event of Default under this Security Agreement, Bank shall not vote any
    securities constituting Collateral except as instructed by Pledgor.

Pledgor hereby appoints Bank its attorney-in-fact to carry out any of the powers
granted by this paragraph.

5. Events of Default. Any one or more of the following shall constitute an event
of default hereunder ("Event of Default") if it has not been cured to the Bank's
satisfaction on or before fifteen calendar days after the date Debtor receives
written notice thereof, in the case of the occurrence of items (a), (b) and/or
(d), below, or, in the case of the occurrence of any event described in items
(c), (e) and/or (f), below, fifteen calendar days after the occurrence thereof."

(a) Debtor fails to pay any Indebtedness when due, or breaches any other term of
    any agreement evidencing the Indebtedness.

(b) Pledgor breaches any term, provision, warranty or representation under this
    Security Agreement.

(c) Any custodian, receiver or trustee is appointed to take possession, custody
    or control of all or a substantial portion of the property of any Debtor or
    Pledgor or of any guarantor of any Indebtedness.

(d) Any Debtor, any Pledgor, or any guarantor of any Indebtedness becomes
    insolvent, or is generally not paying or admits in writing its inability to
    pay its debts as they become due, fails in business, makes a general
    assignment for the benefit of creditors, dies, becomes incompetent, or
    commences any case, proceeding or other action under any bankruptcy or other
    law for the relief of, or relating to, debtors.

(e) Any case, proceeding or other action is commenced against any Debtor, any
    Pledgor or any guarantor of any Indebtedness under any bankruptcy or other
    law for the relief of, or relating to, debtors.

(f) Any involuntary lien of any kind or character attaches to any Collateral.

(g) Any deterioration or impairment of the Collateral or any part thereof or any
    decline or depreciation in the value or market price thereof (whether actual
    or reasonably anticipated), which causes the Collateral in the good faith
    judgment of Bank to become unsatisfactory as to character or value.

6. Remedies. If an Event of Default occurs, Bank may do any one or more of the
following:

(a) Declare any Indebtedness immediately due and payable, without notice or
    demand.

(b) Exercise as to any or all of the Collateral all the rights, powers and
    remedies of an owner (including the right to vote any securities
    constituting Collateral).

(c) Enforce the security interest given hereunder pursuant to the Uniform
    Commercial Code and any other applicable law.

(d) Sell ail or any part of the Collateral at public or private sale, without
    demand, advertisement or notice, in such manner and order as Bank may elect.
    Bank may purchase the Collateral for its own account at any such sale.
    Pledgor acknowledges that Collateral may be sold at a loss to Pledgor, and
    that, in such event, Bank shall have no liability or responsibility to
    Pledgor for such loss.

(e) Enforce the security interest of Bank in any deposit account which is part
    of the Collateral by applying such account to the Indebtedness.

(f) Exercise any other remedy provided under this Security Agreement or by any
    applicable law. Pledgor acknowledges that all such rights and remedies are
    cumulative, and the exercise of any right or remedy shall not preclude the
    further exercise of any other right or remedy.


                                      -2-

   13


7. Waivers. Bank shall be under no duty or obligation whatsoever (a) to make or
give any presentment, demands for performances, notices of nonperformance,
protests, notices of protest or notices of dishonor in connection with any
obligations or evidences of indebtedness held by Bank as Collateral, or in
connection with any obligation or evidences of indebtedness which constitute in
whole or in part the Indebtedness, or (b) to give Pledgor notice of, or to
exercise, any subscription rights or privileges, any rights or privileges to
exchange, convert or redeem or any other rights or privileges relating to or
affecting any Collateral.

8. Additional Waivers. Pledgor waives any right to require Bank to (a) proceed
against any person, (b) proceed against or exhaust any collateral, or (c) pursue
any other remedy in Bank's power; and waives any defense arising by reason of
any disability or other defense of Debtor or any other person, or by reason of
the cessation from any cause whatsoever of the liability of Debtor or any other
person. Until the Indebtedness is paid in full, Pledgor waives any right of
subrogation, reimbursement, indemnification, and contribution (contractual,
statutory or otherwise), including without limitation any claim or right of
subrogation under the Bankruptcy Code (Title 11 of the U.S. Code) or any
successor statute, arising from the existence or performance of this Security
Agreement, and Pledgor waives any right to enforce any remedy which Bank now has
or may hereafter have against Debtor or against any other person and waives any
benefit of and any right to participate in any Collateral or security whatsoever
now or hereafter held by Bank. If any Pledgor is not also a Debtor with respect
to a specified indebtedness, such Pledgor authorizes Bank without notice or
demand and without affecting Pledgor's liability hereunder, from time to time
to: (a) renew, extend, accelerate or otherwise change the time for payment of or
otherwise change the terms of the Indebtedness or any part thereof, including
increase or decrease of the rate of interest thereon; (b) take and hold
security, other than the Collateral, for the payment of the Indebtedness or any
part thereof, and exchange, enforce, waive and release the Collateral or any
part thereof or any such other security; and (c) release or substitute Debtor or
any one or more of them, or any of the endorsers or guarantors of the
Indebtedness or any part thereof, or any other parties thereto.

9. Return of Collateral. Bank may at any time deliver the Collateral or any part
thereof to Pledgor and the receipt of Pledgor shall be a complete and full
acquittance for the Collateral so delivered, and Bank shall thereafter be
discharged from any liability or responsibility therefor.

10. Transfer of Collateral. Upon the transfer of all or any part of the
Indebtedness, Bank may transfer all or any part of the Collateral and shall be
fully discharged thereafter from all liability and responsibility with respect
to such Collateral so transferred, and the transferee shall be vested with all
the rights and powers of Bank hereunder with respect to such Collateral so
transferred; but with respect to any Collateral not so transferred Bank shall
retain all rights and powers hereby given.

11. Continuing Agreement. This is a continuing Security Agreement and all the
rights, powers and remedies hereunder shall apply to all past, present and
future Indebtedness of Debtor or any one or more of them to Bank, including that
arising under successive transactions which shall either continue the
Indebtedness, increase or decrease it, or from time to time create new
Indebtedness after all or any prior Indebtedness has been satisfied, and
notwithstanding the death, incapacity, cessation of business, dissolution or
bankruptcy of Debtor or any one or more of them, or any other event or
proceeding affecting Debtor or any one or more of them.

12. Continuing Powers. Until all Indebtedness shall have been paid in full, the
power of sale and all other rights, powers and remedies granted to Bank
hereunder shall continue to exist and may be exercised by Bank at the time
specified hereunder irrespective of the fact that the Indebtedness or any part
thereof may have become barred by any statute of limitations, or that the
personal liability of Debtor or any one or more of them may have ceased. Pledgor
waives the benefit of any statute of limitations as applied to this Security
Agreement.

13. Custody of Collateral. Bank may, in its discretion, hold some or all of the
Collateral in an account with a custody unit of Bank. Debtor shall reimburse
Bank for the usual custody charges and expenses of Bank's custody unit. Bank
may, in its sole discretion, retain the Collateral in physical form or with a
depository. Bank shall not be required to segregate the Collateral from other
securities owned by third parties. Debtor and Pledgor agree to be bound by the
rules, procedures, practices, liens and assessments of each depository used by
Bank. Bank shall not be liable for any loss to the Collateral resulting from
acts of God, war, civil commotion, fire, earthquake, or other disaster beyond
the reasonable control of Bank, or for any other loss or damage to the
Collateral unless shown to have arisen from Bank's intentional misconduct or
lack of reasonable care.

14. Conflict of Interest. In some cases, some or all of the Collateral may be
held by Bank pursuant to another agreement, other than this Security Agreement,
between Bank and Pledgor (the "Account Agreement"). Pledgor acknowledges that a
conflict may arise between Bank's obligations under the Account Agreement,
including any obligations to direct the Pledgor's investments or to provide
investment advice, and Bank's rights as a lender under this


                                      -3-


   14

Security Agreement. In such event, Pledgor expressly agrees that Bank's rights
as lender shall take precedence over Bank's obligations under the Account
Agreement. Pledgor agrees that all provisions of the Account Agreement that
directly or indirectly prohibit any extension of credit or the grant of a
security interest in the Collateral, or which are contrary to the provisions of
this Security Agreement, are hereby amended to the extent necessary to permit
this Security Agreement to be fully effective according to its terms.

15. Custody of Collateral at Bailee. If permitted by Bank, some or all of the
Collateral may be held at a broker or other bailee (the "Bailee"). Pledgor shall
pay to Bailee any charges or costs imposed by the Bailee. Pledgor at no time
shall request that Bailee release any Collateral to Pledgor, except as expressly
permitted by Bank. Bank may, at any time, require Bailee to do any or all of the
following: (a) disburse any or all of the Collateral to Bank; (b) allow Bank
(and not Pledgor) to exercise any rights relating to the Collateral; (c) sell
some or all of the Collateral and remit the sales proceeds (less Bailee's normal
sales charge) to Bank; and (d) buy and sell Collateral only upon the
instructions of Bank (and not Pledgor).

16. Indemnity ReRardinR Bailee. If Bank permits any of the Collateral to be
maintained at a Bailee, Pledgor hereby agrees to indemnify, defend and hold
harmless Bank, its successors and assigns and its directors, officers, employees
and agents, from and against any and all losses, liabilities, damages,
obligations, deficiencies, payments, costs and expenses (including, without
limitation, costs and expenses of any and all actions, suits, proceedings,
arbitrations, demands, assessments, judgments, settlements, compromises relating
thereto and reasonable attorneys' fees and disbursements in connection
therewith, and including allocated costs of in-house counsel) sustained or
incurred by Bank or any other indemnitee in any way arising from or related to
Bank's actions with respect to Bailee as contemplated herein or contemplated by
any agreement with or notice to Bailee, except such as are due to Bank's willful
misconduct or gross negligence.

17. Trading or Substitution of Collateral. Unless otherwise agreed by Bank, Bank
shall be under no obligation to permit any trading or substitution of the
Collateral or to permit the release of any Collateral or the proceeds thereof
until the Indebtedness has been paid in full.

18. Costs. All advances, charges, costs and expenses, including reasonable
attorneys' fees, incurred or paid by Bank in exercising any right, power or
remedy conferred by this Security Agreement or in the enforcement thereof, and
including the charges and expenses of Bank's custody unit or of any Bailee,
shall become a part of the Indebtedness secured hereunder and shall be paid to
Bank by Debtor and Pledgor immediately and without demand, with interest thereon
at an annual rate equal to the highest rate of interest of any Indebtedness
secured by this Security Agreement (or, if there is no such interest rate, at
the maximum interest rate permitted by law for interest on judgments). Such
costs and attorneys' fees shall include, without limitation, the allocated cost
of in-house counsel.

19. Miscellaneous.

(a) Any waiver, express or implied, of any provision hereunder and any delay or
    failure by Bank to enforce any provision shall not preclude Bank from
    enforcing any such provision thereafter.

(b) Pledgor and Debtor shall, at the request of Bank, execute such other
    agreements, documents, instruments, or financing statements in connection
    with this Security Agreement as Bank may reasonably deem necessary. Pledgor
    hereby appoints Bank as its attorney-in-fact with tull power and authority
    to (i) sign any financing statements which must be executed or filed to
    perfect or continue perfected our security interest in the Collateral, and
    (ii) file any such financing statements by electronic means with or without
    a signature as authorized er required by applicable law or filing
    procedures.

(c) This Security Agreement shall be governed by and construed according to the
    laws of the State of California, to the jurisdiction of which the parties
    hereto submit.

(d) Ail terms not defined herein are used as set forth in the Uniform Commercial
    Code.

(e) This Security Agreement shall benefit Bank's successors and assigns and
    shall bind Pledgor's successors and assigns.

(f) Pledgor shall immediately deliver to Bank (or the Bailee, if any) any
    Collateral now or hereafter in Pledgor's possession.

(g) In all cases where more than one party executes this Security Agreement, all
    words used herein in the singular shall be deemed to have been used in the
    plural where the context and construction so require, and the obligations
    and undertakings hereunder are joint and several.


                                      -4-

   15
In Witness Whereof Pledgor has executed this Security Agreement (by its duly
authorized officer, if Pledgor is not an individual), as of May 8, 1998.

                                       Pledgor:

                                       ChromaVision Medical Systems, Inc.


                                       /s/ DOUG HARRINGTON
                                       ------------------------------------
                                          Doug Harrington
                                          Chief Executive Officer

                                       /s/ KEVIN O'BOYLE
                                       ------------------------------------
                                           Kevin O'Boyle, Vice President, 
                                           and Chief Financial Officer

Pledgor's location (residence 
if Pledgor is an individual;
Chief Executive office if
Pledgor is not an individual)

33171 Paseo Cerveza
San Juan Capistrano, California 92675

Mailing address if different
than above:

- -----------------------------

- -----------------------------

- -----------------------------

If Pledgor's Taxpayer Identification
Number (TIN) to be used for tax reporting
purposes with respect to the Collateral
is 75-2649072

(Check if applicable)

[ ] The Pledgor is not a citizen or resident of the United States; is not a
    legal entity organized under the laws of the United States; and is not doing
    business in the United States.

                     ACKNOWLEDGEMENT AND CONSENT OF DEBTOR

If Debtor is different from Pledgor, such Debtor signs below to acknowledge and
consent to the terms of this Security Agreement.

                                                Debtor:

                                                /s/
                                                --------------------------------




                                      -5-
   16
                        EXHIBIT A TO FINANCING STATEMENT

Debtor:         ChromaVision Medical Systems, inc.
Secured Party:  Bank of America National Trust and Savings Association

                            DESCRIPTION OF COLLATERAL

(a) Account number 01-40-403-0010320 maintained by Bank in the name of Debtor or
    for the benefit of Debtor (or any one or more Debtor), and all successor and
    replacement accounts, regardless of the numbers of such accounts or the
    offices at which such accounts are maintained (the "Accounts") and all
    rights of Debtor in connection with the Accounts.

(b) All investment property, security entitlements, financial assets,
    certificated securities, uncertificated securities, money, deposit accounts,
    instruments, general intangibles, and all other investments or property of
    any sort now or hereafter held, maintained or administered in the Accounts,
    other than any interest in any master notes or variable amount notes.

(c) All rollovers, renewals or reinvestments of any of the foregoing property.

(d) All stock or conversion rights, rights to subscribe, liquidation dividends
    or preferences, stock dividends, dividends, rights to interest, interest
    payments, dividends paid in stock, new securities or other property which
    Debtor (or any one or more Debtor) is or may hereafter become entitled to
    receive on account of any of the foregoing property.

(e) The proceeds, increase and products of any of the foregoing or replacements
    thereof or substitutions therefor.


                                      -6-