SECURITIES AND EXCHANGE COMMISSION

                             Washington, D.C. 20549

                              --------------------

                                    FORM 8-K

                                 CURRENT REPORT

                       Pursuant to Section 13 or 15(d) of
                       the Securities Exchange Act of 1934

              Date of Report (Date of earliest event reported):

                               September 29, 2000

                                -----------------


                          ORASURE TECHNOLOGIES, INC.
            (Exact name of Registrant as specified in its charter)

         Delaware                    1-10492                  36-4370966
      (State or other              (Commission               (IRS Employer
       jurisdiction                 File No.)             Identification No.)
     of incorporation)

                             8505 SW Creekside Place
                          Beaverton, Oregon 97008-7108
               (Address of principal executive offices) (Zip code)

                                 (503) 641-6115
              (Registrant's telephone number, including area code)




Items 2.  Acquisition or Disposition of Assets

      On September  29, 2000,  STC  Technologies,  Inc., a Delaware  corporation
("STC"), and Epitope, Inc., an Oregon Corporation ("Epitope"),  were merged (the
"Mergers") into OraSure Technologies Inc. ("Registrant"), a new corporation that
was formed  under  Delaware  law solely for the  purposes of  combining  the two
companies  and  changing  the state of  incorporation  of Epitope from Oregon to
Delaware.  The companies were merged pursuant to that certain Agreement and Plan
of Merger, dated May 6, 2000 (the "Merger Agreement"), by and among Epitope, the
Registrant  and STC.  The  shareholders  of STC and Epitope  approved the Merger
Agreement on September 29, 2000.

      The Mergers are being accounted for as a "pooling of interests."

      The agreement is a $260 million all stock deal. As a result of the Mergers
(i) each share of STC common stock was converted  into the right to receive five
and two hundred ninety-six one thousandths (5.296) shares of Registrant's common
stock and (ii) each share of Epitope  common stock was converted  into the right
to receive one share of Registrant's common stock.

      Epitope and STC mailed a definitive joint proxy  statement/prospectus (the
"Joint Proxy  Statement/Prospectus")  to their respective stockholders on August
31, 2000,  which sets forth  certain  information  regarding  the  Mergers,  the
Registrant,  Epitope and STC,  including,  but not limited to, the manner of the
Mergers, the nature of any material  relationships  between Registrant,  Epitope
and STC or any officer or director of such  parties and the nature of  Epitope's
and STC' business. The Joint Proxy  Statement/Prospectus  is incorporated herein
as Exhibit 20.1. In addition, the foregoing summary is qualified in its entirety
by reference to the Merger  Agreement,  which is incorporated  herein as Exhibit
2.1.

      OraSure's common stock is registered under Section 12(g) of the Securities
Exchange Act of 1934, as amended (the "Exchange  Act").  OraSure is deemed to be
the successor to Epitope's prior Exchange Act registration,  under Rule 12g-3(a)
promulgated under the Exchange Act.

Item 5.  Other Events

      In connection with the Mergers,  the  Registrant's  board of directors was
reduced from nine to seven members. In addition,  six members of the board -- W.
Charles Armstrong,  Andrew S. Goldstein, G. Patrick Sheaffer, Robert J. Zollars,
Margaret  H.  Jordan and  Michael J.  Paxton --  resigned  as  directors  of the
Registrant.

      The Registrant's  articles of incorporation divides the board of directors
into three classes of directors,  with the directors  serving staggered terms of
three years and until their respective successors are duly elected and qualified
or until their respective earlier resignation or removal. The board of directors
presently is composed of six persons,  three of whom were  designated by Epitope
at the time of the Mergers and three of whom were  designated by STC at the time
of the Mergers. There remains one vacancy on the board.

      The six persons  presently  serving on the board of directors are Frank G.
Hausmann,  Roger L. Pringle,  Robert D. Thompson,  Michael G. Bolton, William W.
Crouse, and Michael J. Gausling.  Messrs.  Hausmann and Bolton are designated as
Class I directors and have been
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appointed to a term expiring at the time of the annual  meeting of  shareholders
in 2001.  Messrs.  Pringle and Crouse are  designated  as Class II directors and
have been  appointed  to a term  expiring  at the time of the annual  meeting of
shareholders in 2002. Messrs.  Thompson and Gausling are designated as Class III
directors  and have been  appointed to a term expiring at the time of the annual
meeting of shareholders in 2003.

Item 7.  Financial Statements and Exhibits

      (a)   Financial Statements of Businesses Acquired.

            The financial statements required by this Item 7(a) of Epitope as of
      September  30,  1999  and  1998  and for  each of the  three  years  ended
      September 30, 1999, 1998, and 1997, are  incorporated  herein by reference
      as Exhibit 20.2. The unaudited  financial  statements for the  nine-months
      ended June 30, 2000 and 1999,  are  incorporated  herein by  reference  to
      Exhibit 20.3.

            The  financial  statements  required  by this Item 7(a) of STC as of
      December 31, 1999 and 1998 and for each of the three years ended  December
      31, 1999, 1998 and 1997 together with unaudited  financial  statements for
      the six-months  ended June 30, 2000 and 1999, are  incorporated  herein by
      reference as Exhibit 20.4.

      (b)   Pro Forma Financial Information.

            The  unaudited  pro forma  balance  sheets  as of June 30,  2000 and
      September 30, 1999 and statements of operations for the nine-months  ended
      June 30, 2000 and 1999, and for the years ended  September 30, 1999,  1998
      and 1997,  required by this Item 7(b) are  incorporated  by  reference  as
      Exhibit 20.5

      (c)   Exhibits.

      Exhibit No.       Description

      Exhibit 2.1       Agreement and Plan of Merger,  dated May 6, 2000, by and
                        among Epitope,  Inc., OraSure Technologies,  Inc. (f/k/a
                        Edward Merger  Subsidiary,  Inc.) and STC  Technologies,
                        Inc. (filed with the Registrant's  Form S-4 Registration
                        Statement (File No.  333-39210) as ANNEX A thereto,  and
                        incorporated herein by reference).

      Exhibit 20.1      Joint Proxy Statement/Prospectus (filed as a part of the
                        Registrant's  Form S-4 Registration  Statement (File No.
                        333-39210) and incorporated herein by reference)..

      Exhibit 20.2      Audited financial  statements of Epitope as of September
                        30,  1999 and 1998 and for each of the three years ended
                        September 30, 1999, 1998, and 1997 (filed with Epitope's
                        Annual Report on Form 10-K for the year ended  September
                        30, 1999, and incorporated herein by reference).

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      Exhibit 20.3      Unaudited  financial   statements  of  Epitope  for  the
                        nine-months  ended June 30, 2000  (filed with  Epitope's
                        Quarterly Report on Form 10-Q for the nine-months  ended
                        June 30, 2000, and incorporated herein by reference).

      Exhibit 20.4      The financial  statements of STC as of December 31, 1999
                        and 1998 and for each of the three years ended  December
                        31,  1999,   1998  and  1997  together  with   unaudited
                        financial  statements for the six-months  ended June 30,
                        2000 and 1999 (filed as a part of the Registrant's  Form
                        S-4  Registration  Statement  (File No.  333-39210)  and
                        incorporated herein by reference).


      Exhibit 20.5      Unaudited pro forma  balance  sheets as of June 30, 2000
                        and September 30, 1999 and  statements of operations for
                        the  nine-months  ended June 30, 2000 and 1999,  and for
                        the years ended September 30, 1999, 1998 and 1997 (filed
                        as a part  of the  Registrant's  Form  S-4  Registration
                        Statement (File No.  333-39210) and incorporated  herein
                        by reference).

                                     SIGNATURES


      Pursuant to the  requirements of the Securities  Exchange Act of 1934, the
registrant  has duly  caused  this  report  to be  signed  on its  behalf by the
undersigned, hereunto duly authorized.

                                    ORASURE TECHNOLOGIES, INC.


Date:  October 13, 2000             By: /s/ Charles E. Bergeron
                                        --------------------
                                        Charles E. Bergeron



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                                  EXHIBIT INDEX


      Exhibit No.       Description

      Exhibit 2.1       Agreement and Plan of Merger,  dated May 6, 2000, by and
                        among Epitope,  Inc., OraSure Technologies,  Inc. (f/k/a
                        Edward Merger  Subsidiary,  Inc.) and STC  Technologies,
                        Inc. (filed with the Registrant's  Form S-4 Registration
                        Statement (File No.  333-39210) as ANNEX A thereto,  and
                        incorporated herein by reference).

      Exhibit 20.1      Joint Proxy Statement/Prospectus (filed as a part of the
                        Registrant's  Form S-4 Registration  Statement (File No.
                        333-39210) and incorporated herein by reference)..

      Exhibit 20.2      Audited financial  statements of Epitope as of September
                        30,  1999 and 1998 and for each of the three years ended
                        September 30, 1999, 1998, and 1997 (filed with Epitope's
                        Annual Report on Form 10-K for the year ended  September
                        30, 1999, and incorporated herein by reference).

      Exhibit 20.3      Unaudited  financial   statements  of  Epitope  for  the
                        nine-months  ended June 30, 2000  (filed with  Epitope's
                        Quarterly Report on Form 10-Q for the nine-months  ended
                        June 30, 2000, and incorporated herein by reference).

      Exhibit 20.4      The financial  statements of STC as of December 31, 1999
                        and 1998 and for each of the three years ended  December
                        31,  1999,   1998  and  1997  together  with   unaudited
                        financial  statements for the six-months  ended June 30,
                        2000 and 1999 (filed as a part of the Registrant's  Form
                        S-4  Registration  Statement  (File No.  333-39210)  and
                        incorporated herein by reference).


      Exhibit 20.5      Unaudited pro forma  balance  sheets as of June 30, 2000
                        and September 30, 1999 and  statements of operations for
                        the  nine-months  ended June 30, 2000 and 1999,  and for
                        the years ended September 30, 1999, 1998 and 1997 (filed
                        as a part  of the  Registrant's  Form  S-4  Registration
                        Statement (File No.  333-39210) and incorporated  herein
                        by reference).


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