ORASURE TECHNOLOGIES, INC.
                            MANAGEMENT INCENTIVE PLAN



ARTICLE I
                              OBJECTIVE OF THE PLAN

The purpose of this  Management  Incentive  Plan  ("Plan" or "MIP") is to reward
executives of ORASURE TECHNOLOGIES,  INC. (the "Company") for creating value for
the Company by maximizing financial performance against stated objectives.


ARTICLE II
                               PLAN ADMINISTRATION

The Plan is administered by the Board's Compensation Committee (the "Committee")
and all  matters  shall be  decided on by  general  consensus  as defined in the
Committee's Charter.

The Plan is an annual  program and is effective  January 1, 2001 and will remain
in effect until the Compensation Committee determines otherwise. A new Plan year
will commence on the first business day of the fiscal year.

ARTICLE III
                                  PARTICIPANTS

Generally  all active  managerial  employees  and above,  currently  meeting job
requirements,  shall be eligible to  participate in the Plan.  Participation  is
limited to those employees selected by the Compensation Committee to participate
in the Plan during each fiscal year.


ARTICLE IV
                             PERFORMANCE OBJECTIVES

Prior to or at the  beginning of each fiscal year,  the  Compensation  Committee
shall establish:

      (i)  performance  objectives  for  the  Company,  any  Subsidiary,  or any
business segment or unit of the Company, based upon such criteria as may be from
time to time considered by the Compensation Committee, and

      (ii) the award formula or matrix by which all bonuses under this Plan will
be calculated and determined for Compensation Committee review and approval.

The  maximum  bonus that may be awarded  under this Plan to any one  participant
shall be 200% of a participant's bonus target.


ARTICLE V
                               AWARD CALCULATIONS

Each Plan  participant  will be assigned a target  award that will be awarded if
the Company achieves its targeted performance goals. These target awards will be
leveraged up when




Company performance exceeds  expectations,  or down if Company performance falls
below expectations. Following are the target awards by position.

          CEO - 50%
          COO/CSO - 40%
          Senior Vice Presidents - 30%
          Vice Presidents - 20%
          Directors - 15%
          Managers - 5%

A  bonus  pool  will  be  funded  based  on the  Company's  performance  against
pre-established  SALES goals and  EARNINGS  PER SHARE (EPS) goals (see Table A).
For example,  per the approved budget,  in 2001 if Sales are $43 Million and the
EPS is $0.10 per share, then 100% of the incentive pool will be funded. The pool
is determined by aggregating  targeted awards for all participants.  Awards will
be  interpolated  for  performance  results  that fall  between  numbers  on the
Corporate Award Performance Matrix.

                                     TABLE A
                       Corporate Award Performance Matrix
              ----------------------------------------------------------
                                       EPS
              ----------------------------------------------------------
                       $.075        $.010       $.125         $.15
              ----------------------------------------------------------
              $51.6      125%         150%        175%         200%
              ----------------------------------------------------------
              $47.3      100%         125%        150%         175%
              ----------------------------------------------------------
     SALES    $43.0       75%         100%        125%         150%
              ----------------------------------------------------------
              $38.7       50%          75%        100%         125%
              ----------------------------------------------------------

After  the  Corporate  Award  pool is  determined,  managers  will then have the
opportunity to recommend adjustments to the CEO for each participant's Corporate
Award for Individual performance.  Awards for the CEO, COO, CSO, and CFO will be
based 75% on reaching  corporate  revenue  objectives  and 25% on  non-financial
objectives/measures. Awards for all other officers will be based 50% on reaching
corporate  objectives  and 50%  based on  non-financial  objectives.  All  other
individual performance will be based on a participant's performance rating under
the Company's performance evaluation program.  Awards may be adjusted up or down
up  to  50%  based  on  Individual  performance.  However  any  adjustment  must
ultimately result in a zero sum.

ARTICLE VI
                             ADMINISTRATIVE MATTERS

As soon as practicable  after each Plan year, the  Compensation  Committee shall
determine whether the Company,  any Subsidiary,  or any business segment or unit
of the Company attained their pre-established  performance objectives.  Assuming
such  performance  objectives are attained,  the  Compensation  Committee  shall
determine,  in its sole and exclusive  discretion,  whether any bonuses shall be
awarded for such Plan year. Such bonuses shall be awarded as soon as practicable
thereafter  and the Plan  participants  who are entitled to receive such bonuses
shall be promptly notified of the award thereof.

In  the  event  that a Plan  participant  transfers  in to a  position  that  is
designated as eligible for Plan participation, then any earned bonus in the Plan
year will be prorated as of the month in which the



transfer  occurred.  If a Plan  participant  transfers  into a position  that is
designated  not eligible for Plan  participation,  the employee will forfeit any
participation in the plan.

In  the  event  of  death,  permanent  disability,   retirement  or  involuntary
termination  without  cause,  unpaid  bonuses will be  calculated on a pro-rated
basis by taking  the  number of full  months,  including  the month in which the
terminating event occurred, and dividing those months by twelve.

In the event of voluntary termination or involuntary  termination for cause, the
Plan participant will forfeit any unpaid bonus earned under this Plan.

A Plan  participant  not employed by the Company or a Subsidiary on the last day
of the Plan  year  will  forfeit  his or her  earned  but  unpaid  bonus  unless
otherwise determined by the Compensation Committee.

ARTICLE VII
                             NO ENTITLEMENT TO BONUS

Plan  participants are entitled to a distribution  under this Plan only upon the
approval of the award by the Compensation  Committee and no Participant shall be
entitled to a bonus  under the Plan unless the bonus is based on the  attainment
of performance objectives defined under the Plan.

ARTICLE VIII
                              TERMINATION OF PLAN

The Compensation  Committee reserves the right to amend or terminate the Plan at
any time within thirty days written notice to Plan participants. In the event of
a Plan  termination,  Plan  participants  will continue to be eligible for bonus
awards,  if earned,  for the current Plan year.  Bonus awards will be calculated
from the date of the Plan  termination and payable as soon as practicable  after
the end of the Plan year.

ARTICLE IX
                      PARTICIPANT'S RIGHT OF ASSIGNABILITY

Participant  awards  shall  not  be  subject  to  assignment,  pledge  or  other
disposition,  nor shall such  amounts be  subject  to  garnishment,  attachment,
transfer by operation of law, or any legal process.

Nothing  contained  in this  Plan  shall  confer  upon  employees  any  right to
continued employment, nor interfere with the right of the Company to terminate a
participant's  employment from the Company.  Participation  in the Plan does not
confer rights to  participation in other Company  programs,  including annual or
long-term  incentive plans,  non-qualified  retirement or deferred  compensation
plans or other executive perquisite programs.