SECURITIES AND EXCHANGE COMMISSION

                             Washington, D.C. 20549

                                 --------------

                                    Form 8-K

                                 CURRENT REPORT

                       Pursuant to Section 13 or 15(d) of
                       the Securities Exchange Act of 1934

                Date of Report (Date of earliest event reported):

                                  July 28, 1997

                                 --------------

                                  EPITOPE, INC.
               (Exact name of Registrant as specified in charter)

                                     Oregon
                 (State or other jurisdiction of incorporation)

                                     1-10492
                              (Commission File No.)

                                   93-0779127
                        (IRS Employer Identification No.)

             8505 S.W. Creekside Place
                  Beaverton, Oregon                         97008
       (Address of principal executive offices)           (Zip Code)

               Registrant's telephone number, including area code:
                                 (503) 641-6115






Item 5.  Other Events.

                  On July 28, 1997,  Epitope,  Inc.  (the  "Company"),  issued a
press release announcing two significant corporate events.

                  The  Company  intends  to spin off its  Agritope  agricultural
biotechnology  unit, subject to obtaining  additional capital from investors and
strategic partners to support the unit's operation as a separate business and to
receipt of regulatory approval.

                  The Company will re-acquire from SmithKline Beecham plc ("SB")
all rights to the Company's patented oral fluid diagnostic  technology  pursuant
to termination of its Development, License and Supply Agreement with SB.

                  A copy of the press  release is attached as an exhibit to this
report.

Item 7.  Financial Statements, Pro Forma Financial Information and Exhibits.

                  (a)  Not applicable.

                  (b)  Not applicable.

                  (c)  Exhibits.

                  The  exhibit to this  report is listed in the exhibit  index
following the signature page.






                                   SIGNATURES

                  Pursuant to the requirements of the Securities Exchange Act of
1934,  the  Registrant has duly caused this report to be signed on its behalf by
the undersigned hereunto duly authorized.

                                      EPITOPE, INC.


Dated:  July 28, 1997                 By /s/ W. Charles Armstrong
                                         W. Charles Armstrong
                                         President and Chief Executive Officer






                                  EXHIBIT INDEX

99       Press release of Epitope, Inc., dated July 28, 1997.