SECURITIES AND EXCHANGE COMMISSION

                             Washington, D.C. 20549

                                -----------------

                                    FORM 8-K

                                 CURRENT REPORT

                       Pursuant to Section 13 or 15(d) of
                       the Securities Exchange Act of 1934

                Date of Report (Date of earliest event reported):

                                December 10, 1997

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                                  EPITOPE, INC.
               (Exact name of Registrant as specified in charter)

                                     Oregon
                 (State or other jurisdiction of incorporation)

                                     1-10492
                              (Commission File No.)

                                   93-0779127
                        (IRS Employer Identification No.)

         8505 S.W. Creekside Place
             Beaverton, Oregon                                    97008
    (Address of principal executive offices)                    (Zip Code)

               Registrant's telephone number, including area code:

                                 (503) 641-6115






Item 5.  Other Events.

                  On December 10, 1997,  Epitope,  Inc. (the "Company") issued a
press release  regarding a research and development  agreement between Agritope,
Inc., the Company's  wholly owned subsidiary  ("Agritope"),  and Vilmorin & Cie,
and a related agreement for sale of Agritope preferred stock to Vilmorin & Cie.

                  A copy of the press  release  is filed as an  exhibit  to this
report.


Item 7.  Financial Statements, Pro Forma Financial Information and Exhibits.

                  (a)      Not applicable.

                  (b)      Not applicable.

                  (c)      Exhibits.

The  exhibits  filed  herewith  are listed in the exhibit  index  following  the
signature page of this report.






                                   SIGNATURES

Pursuant  to the  requirements  of the  Securities  Exchange  Act of  1934,  the
Registrant  has duly  caused  this  report  to be  signed  on its  behalf by the
undersigned hereunto duly authorized.

                                  EPITOPE, INC.


Dated:  December 10, 1997         By: /s/ Gilbert N. Miller
                                  Gilbert N. Miller
                                  Executive Vice President and Chief Financial
                                  Officer







                                  EXHIBIT INDEX

99       Press release dated December 10, 1997.