SECURITIES AND EXCHANGE COMMISSION

                             Washington, D.C. 20549

                                -----------------

                                    FORM 8-K

                                 CURRENT REPORT

                       Pursuant to Section 13 or 15(d) of
                       the Securities Exchange Act of 1934

                Date of Report (Date of earliest event reported):

                                December 24, 1997

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                                  EPITOPE, INC.
               (Exact name of Registrant as specified in charter)

                                     Oregon
                 (State or other jurisdiction of incorporation)

                                     1-10492
                              (Commission File No.)

                                   93-0779127
                        (IRS Employer Identification No.)

     8505 S.W. Creekside Place                                     97008
           Beaverton, Oregon                                     (Zip Code)
  (Address of principal executive offices)

               Registrant's telephone number, including area code:

                                 (503) 641-6115









Item 5.        Other Events

               On  December  24 and  December  29,  1997,  Epitope,  Inc.  ("the
Company"),  issued  press  releases  announcing  that  the  record  date for the
spin-off of Agritope,  Inc., would be December 26, 1997 (the "Record Date"), and
providing other information regarding the spin-off. Copies of the press releases
are attached to this form as exhibits.

               Pursuant to resolutions  adopted by the Board of Directors of the
Company,  the Company also issued a dividend  distribution of one Right for each
outstanding  share of common stock,  no par value (the "Common  Stock"),  of the
Company to the  shareholders  of record at the close of  business  on the Record
Date.  Each Right  entitles the  registered  holder to purchase from the Company
1/1,000 of a share of Series A Junior Participating  Cumulative Preferred Stock,
no par  value  (the  "Preferred  Shares"),  at a  price  of $60 per  share  (the
"Purchase  Price"),  subject to  adjustment.  The  description  and terms of the
Rights are set forth in a Rights  Agreement dated December 15, 1997 (the "Rights
Agreement"),  between the Company and ChaseMellon Shareholder Services,  L.L.C.,
as Rights Agent (the "Rights Agent").

               Initially,  the  Rights  will be  attached  to all  Common  Stock
certificates representing shares then outstanding,  and no separate certificates
evidencing Rights ("Right Certificates") will be distributed.  Until the earlier
of the close of business on (i) the tenth day after a public announcement that a
person or group of affiliated or associated  persons  (other than the Company or
its employee benefit plans) (an "Acquiring Person"),  acquired,  or obtained the
right to acquire,  beneficial ownership of 15 percent or more of the outstanding
shares of Common  Stock and (ii) the tenth  business  day (or such later date as
may be determined by the Board of Directors)  after the  commencement of (or the
announcement  of an  intention  to make) a tender  offer or  exchange  offer the
consummation  of which would result in the  beneficial  ownership by a person or
group of 15  percent  or more of the  outstanding  shares of Common  Stock,  the
Rights will be evidenced,  with respect to any of the Common Stock  certificates
outstanding  as of the Record  Date,  by such  Common  Stock  certificates.  The
earlier of the dates  described  in clauses (i) and (ii) above is referred to as
the "Distribution Date."

               Until the Distribution  Date, the Rights will be transferred with
and only with the Common Stock. As long as the Rights are attached to the Common
Stock,  the  Company  will issue one Right with each share of Common  Stock that
becomes  outstanding so that all outstanding  shares will have attached  Rights.
Until the  Distribution  Date (or the earlier  redemption  or  expiration of the
Rights),  (i)  Common  Stock  certificates  issued  after the  Record  Date upon
transfer or new issuance of Common Stock will contain a legend incorporating the
Rights  Agreement  by  reference  and (ii) the  surrender  for  transfer  of any
certificates  evidencing  Common Stock will also  constitute the transfer of the
Rights associated with the Common Stock represented by such certificate. As soon
as practicable  following the  Distribution  Date,  Right  Certificates  will be
mailed to holders of record of


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the Common Stock as of the close of business on the  Distribution  Date and such
separate Right Certificates alone will evidence the Rights.

               The Rights are not exercisable  until the Distribution  Date. The
Rights will expire (i) at the close of business on December 26, 2007,  (ii) upon
exchange by the  Company  for Common  Stock as  described  below,  or (iii) upon
redemption by the Company as described below, whichever is earliest.

               In the event that any person becomes an Acquiring Person,  proper
provision  shall be made so that each  holder  of a Right  (except  as  provided
below) will  thereafter  have the right to receive upon  exercise that number of
shares of Common  Stock of the  Company  having a market  value of two times the
exercise  price of the Right.  No such  adjustment  to the Rights  will be made,
however,  if a person  becomes  an  Acquiring  Person  pursuant  to a tender  or
exchange offer for all outstanding Common Stock at a price and on terms that are
fair to and otherwise in the best interests of the Company and its shareholders,
as determined by a majority of the Board of Directors in the manner described in
the Rights Agreement (a "Qualifying Offer").

               In the event that, after any person becomes an Acquiring  Person,
the Company is acquired in a merger or other  business  combination  transaction
(other  than a  transaction  made  pursuant  to a  Qualifying  Offer and meeting
certain other requirements  described in the Rights Agreement),  or more than 50
percent of its assets or earning power is sold,  proper  provision shall be made
so that each holder of a Right (except as provided  below) will  thereafter have
the right to receive,  upon the exercise at the then current  exercise  price of
the Right,  that number of shares of common stock of the  acquiring or surviving
company having a market value of two times the exercise price of the Right.

               Following the  occurrence  of any of the events  described in the
preceding  two  paragraphs  (other  than those  events  relating  to  Qualifying
Offers),  any Rights that are or (under certain  circumstances  specified in the
Rights  Agreement)  were,  beneficially  owned  by any  Acquiring  Person  shall
immediately become null and void.

               The Purchase Price payable, and the number of Preferred Shares or
other securities or property  issuable,  upon exercise of the Rights are subject
to adjustment from time to time to prevent dilution.

               The Company is not required to issue fractional  Preferred Shares
other than  fractions in multiples of 1/1,000 of a share.  In lieu of fractional
Preferred Shares, an adjustment in cash may be made based on the market price of
the Preferred Shares on the last trading date prior to the date of exercise.

               At any time  prior to the tenth day  following  the first  public
announcement of the existence of an Acquiring Person, the Company may redeem the
Rights in whole, but


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not in part, at a price of $.01 per Right (the "Redemption Price").  Immediately
upon the action of the Board of Directors  ordering the redemption of the Rights
(or at such time and date thereafter as the Board of Directors may specify), the
right to exercise the Rights will terminate and the only right of the holders of
Rights will be to receive the Redemption Price.

               At any time after a person becomes an Acquiring  Person and prior
to the  acquisition  by  such  Acquiring  Person  of 50  percent  or more of the
outstanding  shares of Common Stock,  the Company may exchange the Rights (other
than Rights  beneficially  owned by such Acquiring  Person which became null and
void), in whole or in part, for Common Stock at the rate of one share per Right,
subject to adjustment.

               Until a Right is exercised,  the holder  thereof,  as such,  will
have no rights as a shareholder of the Company,  including,  without limitation,
the right to vote or to receive dividends.

               Prior to the time a  person  becomes  an  Acquiring  Person,  the
provisions  of the Rights  Agreement  may be amended in any manner.  Thereafter,
with certain  exceptions,  the provisions of the Rights Agreement may be amended
in order to cure any ambiguity,  defect or inconsistency,  to make changes which
do not  adversely  affect the  interests  of holders  of Rights  (excluding  the
interest of any  Acquiring  Person),  or to shorten or lengthen  any time period
under the Rights Agreement;  provided,  however, that no amendment to adjust the
time period  governing  redemption  shall be made at such time as the Rights are
not redeemable.

               The Rights have certain  anti-takeover  effects.  The Rights will
cause  substantial  dilution  to a person or group of persons  that  attempts to
acquire  the  Company,  other  than in a  transaction  approved  by the Board of
Directors  of the Company at a time when the Rights are  redeemable.  The Rights
should not interfere with any acquisition,  merger or other business combination
approved by the Board of Directors at a time when the Rights are redeemable.

               The Rights Agreement and the Restated  Articles of Incorporation,
as  amended,  setting  forth  the  terms of the  Preferred  Shares  are filed as
exhibits to this report and are incorporated herein by reference.  The foregoing
description  of the Rights does not purport to be complete  and is  qualified in
its entirety by reference to the Rights  Agreement and the Restated  Articles of
Incorporation, as amended.


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Item 7.        Financial  Statements,   Proforma  Financial   Information,   and
               Exhibits

               (c)     Exhibits.

               The  exhibits  filed  herewith  are listed in the  exhibit  index
following the signature page of this report.


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                                   SIGNATURES


               Pursuant to the  requirements  of the Securities  Exchange Act of
1934,  the  Registrant has duly caused this report to be signed on its behalf by
the undersigned hereunto duly authorized.

                                            EPITOPE, INC.



Dated:  December 29, 1997                   By: /s/ Charles E. Bergeron
                                                    Charles E. Bergeron
                                                    Vice President of Operations





                                  EXHIBIT INDEX


       3       Restated Articles of Incorporation,  as amended, of Epitope, Inc.
               Incorporated  by  reference  to  Exhibit  3  to  Epitope,  Inc.'s
               Registration  Statement on Form 8-A filed December 26, 1997 (File
               No. 000-15337) (the "Form 8-A").


       4       Rights Agreement dated as of December 15, 1997,  between Epitope,
               Inc., and ChaseMellon Shareholder Services,  L.L.C.  Incorporated
               by reference to Exhibit 4.1 to the Form 8-A.

      99.1     Description of Capital Stock of Epitope, Inc.

      99.2     Press  release issued December 24, 1997.

      99.3     Press release issued December 29, 1997.