1 AS FILED WITH THE SECURITIES AND EXCHANGE COMMISSION, ON DECEMBER 12, 2000 REGISTRATION NO. 333-____ - -------------------------------------------------------------------------------- SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 --------------------------- FORM S-8 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 --------------------------- CELL PATHWAYS, INC. (Exact Name of Registrant as Specified in its Charter) --------------------------- Delaware 23-2969600 (State or Other Jurisdiction of (I.R.S. Employer Identification No.) Incorporation or Organization) 702 Electronic Drive Horsham, PA 19044 (215) 706-3800 (Address of Principal Executive Offices) CELL PATHWAYS, INC. 1997 EQUITY INCENTIVE PLAN CELL PATHWAYS, INC. 1997 NON-EMPLOYEE DIRECTORS' STOCK OPTION PLAN CELL PATHWAYS, INC. EMPLOYEE STOCK PURCHASE PLAN TSENG LABS, INC. 1991 STOCK OPTION PLAN TSENG LABS, INC. 1991 SPECIAL DIRECTORS STOCK OPTION PLAN TSENG LABS, INC. 1995 STOCK OPTION PLAN (Full Title of the Plans) MARTHA E. MANNING, ESQUIRE Senior Vice President, General Counsel and Secretary Cell Pathways, Inc. 702 Electronic Drive Horsham, PA 19044 (215) 706-3800 (Name, Address and Telephone Number, Including Area Code, of Agent for Service) --------------------------- Copies To: Stephen A. Jannetta, Esq. Morgan, Lewis & Bockius LLP 1701 Market Street Philadelphia, PA 19103-2921 (215) 963-5000 CALCULATION OF REGISTRATION FEE TITLE PROPOSED MAXIMUM PROPOSED MAXIMUM OF SECURITIES TO AMOUNT OFFERING PRICE AGGREGATE BE REGISTERED(1) TO BE REGISTERED PER SHARE OFFERING PRICE AMOUNT OF REGISTRATION FEE - ---------------- ---------------- --------- -------------- -------------------------- Common Stock 3,250,015(2) $4.625 $15,031,319.37 $3,968.27 (par value $0.01) (1) Includes rights to purchase shares of the Registrant's Series A Junior Participating Stock pursuant to the Preferred Stock Purchase Rights Plan of Cell Pathways, Inc. No separate consideration is paid for these rights and, as a result, the registration fee for these rights is included in the fee for the Common Stock registered hereby. Pursuant to Rule 416 under the Securities Act of 1993, as amended (the "Securities Act"), this registration statement also covers such additional shares as may hereafter be offered or issued to prevent dilution resulting from stock splits, stock dividends, recapitalizations or certain other capital adjustments. (2) For purposes of calculating the registration fee on the shares of Common Stock being registered pursuant to this Registration Statement, the maximum offering price per share has been estimated at $4.625 based upon the average of the high and low prices of the Common Stock, as reported in the Nasdaq National Market on December 6, 2000. 2 INCORPORATION BY REFERENCE Pursuant to General Instruction E on Form S-8 under the Securities Act, the contents of the Registrant's Registration Statement on Form S-8 (Commission File No. 333-66701) is incorporated herein by reference. 3 ITEM 8: EXHIBITS Exhibit # Description - --------- ----------- 5 Opinion of Morgan, Lewis & Bockius LLP. 23.1 Consent of Morgan, Lewis & Bockius LLP (included in Exhibit 5). 23.2 Consent of Arthur Andersen LLP. 24 Power of Attorney (included in signature page). 99 Cell Pathways 1997 Equity Incentive Plan (as amended and restated). 4 SIGNATURES Pursuant to the requirements of the Securities Act of 1933, the Registrant certifies that it has reasonable grounds to believe that it meets all of the requirements for filing on Form S-8 and has duly caused this Registration Statement to be signed on its behalf by the undersigned, thereunto duly authorized, in the City of Horsham, Commonwealth of Pennsylvania, on this 12 day of December, 2000. CELL PATHWAYS, INC. By: /s/ Robert J. Towarnicki -------------------------------- Robert J. Towarnicki President and Chief Executive Officer KNOW ALL MEN BY THESE PRESENTS, that each person whose signature appears below hereby constitutes and appoints Robert J. Towarnicki and Martha E. Manning, and each of them, his or her true and lawful attorneys-in-fact and agents, with full power of substitution and resubstitution, for him or her and in his or her name, place and stead, in any and all capacities, to sign any and all amendments to this Registration Statement (including post-effective amendments to the Registration Statement), and to file the same, with all exhibits thereto, and any other documents in connection therewith, granting unto said attorneys-in-fact and agents full power and authority to do and perform each and every act and thing requisite and necessary to be done in and about the premises, as fully to all intents and purposes as he or she might or could do in person, hereby ratifying and confirming all that said attorneys-in-fact and agents, or their substitute or substitutes, may lawfully do or cause to be done by virtue hereof. Pursuant to the requirements of the Securities Act of 1933, as amended, this Registration Statement has been signed below by the following persons in the capacities and on the dates indicated. Signature Title Date - --------- ----- ---- /s/ Robert J. Towarnicki President, Chief Executive Officer December 12, 2000 - ------------------------ (Principal Executive Officer) and Robert J. Towarnicki Chairman of the Board of Directors /s/ Brian J. Hayden Chief Financial Officer, Vice December 12, 2000 - ------------------------ President -- Finance (Principal Brian J. Hayden Financial and Accounting Officer) 5 Signature Title Date - --------- ----- ---- /s/ William A. Boeger Director December 12, 2000 - ----------------------- William A. Boeger /s/ John J. Gibbons Director December 12, 2000 - ----------------------- John J. Gibbons /s/ Thomas M. Gibson Director December 12, 2000 - ----------------------- Thomas M. Gibson /s/ Judith A. Hemberger Director December 12, 2000 - ----------------------- Judith A. Hemberger /s/ Bruce R. Ross Director December 12, 2000 - ------------------------ Bruce R. Ross /s/ Rifat Pamukcu Director and Executive Vice President December 12, 2000 - ------------------------ -- Chief Scientific Officer Rifat Pamukcu /s/ Louis M. Weiner Director December 12, 2000 - ----------------------- Louis M. Weiner 6 EXHIBIT INDEX 5 Opinion of Morgan, Lewis & Bockius LLP. 23.1 Consent of Morgan, Lewis & Bockius LLP (included in Exhibit 5). 23.2 Consent of Arthur Andersen LLP. 24 Power of Attorney (included in signature page). 99 Cell Pathways 1997 Equity Incentive Plan (as amended and restated).