Exhibit 10.48

                                 PROMISSORY NOTE

$558,000.00                                                  NOVEMBER 20th, 2003

      FOR VALUE RECEIVED, DREW SCIENTIFIC, INC., a Texas corporation
("Borrower"), promises to pay to the order of TEXAS MEZZANINE FUND INC.
("Lender"), located at 351 West Jefferson Blvd., Suite 800, Dallas, Texas 75208,
or such other place as the holder of this Note may from time to time designate
in writing, the principal sum of Five Hundred Fifty-Eight Thousand and No/100
Dollars ($558,000.00), or so much thereof as may be advanced in lawful money of
the United States, with interest accruing on the unpaid principal balance from
time to time remaining unpaid prior to maturity as follows:

      1. Payments of Principal and Interest. The principal and interest of this
Note shall be payable as follows:

            (a) Interest on the Note shall accrue at the rate of 8.0% per annum
      (the "Base Rate"), subject to adjustment as provided for in subparagraph
      l(b) below, and shall be calculated at a daily rate equal to 1/360th of
      the annual percentage rate which this Note bears, based on the actual
      number of days elapsed.

            (b) On July 1, 2005, and thereafter on June 1 of each succeeding
      year thereafter, the interest rate on the Note shall be adjusted to a rate
      equal to the lesser of (i) the greater of the Base Rate or the Prime Rate
      (as hereafter defined) plus 4.0% (the "Stated Rate"), or (ii) the Maximum
      Rate (as hereafter defined). The "Prime Rate" is the rate published by the
      Wall Street Journal as the prime rate. If the Stated Rate at any time
      exceeds the Maximum Rate, the actual rate of interest to accrue on the
      unpaid principal amount of the Note will be limited to the Maximum Rate,
      but any subsequent reductions in the Stated Rate due to reductions in the
      Prime Rate will not reduce the interest rate payable upon the unpaid
      principal amount of the Note below the Maximum Rate until the total amount
      of interest accrued on this Note equals the amount of interest which would
      have accrued if the Stated Rate had at all times been in effect.

            (c) Installments equal to the amount of all accrued interest only
      shall be due and payable monthly commencing on the 1st day of January,
      2004, and on the 1st day of each consecutive month through and including
      June, 2004.

            (d) Installments of principal and interest in the amount of Fourteen
      Thousand Two Hundred and No/100 Dollars ($14,200.00) shall be due and
      payable monthly commencing on the 1st day of July, 2004, with a like
      installment due and payable on the first day of each succeeding month
      thereafter to maturity. All payments made as scheduled on this Note (i.e.,
      after deducting all other charges and impositions prescribed elsewhere in
      this Note or in documents securing payment of this Note) shall be applied,
      to the extent thereof, first to accrued but unpaid interest and the
      balance to unpaid principal.

      2. Maturity. This Note shall mature (i.e., all outstanding principal,
together with all accrued interest which has not been paid, shall be due and
payable in full) on June 1, 2008.

      3. Prepayment. For the purposes of this paragraph 3, the term "prepayment"
shall mean an event whereby the loan evidenced by this Note is voluntarily fully
satisfied prior to the maturity date and shall not include any payment after
default, any payment after the acceleration of this Note, any payment by any
sale under court order, foreclosure, power of sale or deed in lieu of
foreclosure, or any payment by sale or other method under any bankruptcy or
insolvency proceedings, or any prepayment due to the receipt of insurance
proceeds or condemnation awards. Borrower shall have the right to prepay all,
but not part, of the unpaid principal balance of this Note provided the
following conditions are satisfied:

            (a) Borrower is not in default under the terms of this Note, the
      Security Instrument (as defined below) or any other document evidencing,
      governing or securing the loan evidenced by this Note (collectively, the
      "Loan Documents").

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PROMISSORY NOTE - Page 1                             BORROWER _______________



            (b) Borrower has notified Lender in writing of its election and
      commitment to prepay at least thirty (30) days prior to the date the
      prepayment will be made (the "Prepayment Date"), with such notice to
      specify the Prepayment Date and the total amount of all sums to be paid.

            (c) Borrower pays Lender a prepayment fee equal to:

                  (i) Twenty Thousand and No/100 Dollars ($20,000.00) in the
            event prepayment occurs on or prior to March 31, 2005;

                  (ii) Fifteen Thousand and No/100 Dollars ($15,000.00) in the
            event prepayment occurs during the period commencing on April 1,
            2005 and ending March 31, 2006; and

                  (iii) Ten Thousand and No/100 Dollars ($10,000.00) in the
            event prepayment occurs during the period commencing on April 1,
            2006 and ending March 31, 2007.

      No prepayment fee shall be due in the event prepayment occurs on or after
      April 1, 2007.

            (d) Any prepayment of principal permitted hereunder shall be
      accompanied by payment of all unpaid accrued interest on this Note and all
      other sums then due and payable pursuant to this Note, the Security
      Instrument and any other Loan Document.

            (e) Borrower and Lender acknowledge and agree that if the unpaid
      principal balance of this Note is prepaid, then Lender shall receive the
      applicable prepayment fee as partial compensation for the cost to Lender
      of reinvesting the prepayment proceeds and for the loss to Lender of the
      contracted for return on the loan evidenced by this Note. Borrower and
      Lender further acknowledge and agree that the applicable prepayment fee is
      reasonable.

      4. Partial Payment. If Lender at any time receives or accepts payment from
or for the account of Borrower of less than the full amount when due on this
Note, such receipt or acceptance shall, unless Lender expressly agrees otherwise
in writing, be deemed a payment on account only, and shall not cure any default
existing by reason of failure to pay the full amount when due, nor preclude the
exercise of any remedy of Lender including, but not limited to, acceleration of
any unmatured portion hereof, or foreclosure on any security.

      5. Security Instrument. This Note is secured by, among other things, the
provisions of a certain Security Agreement (the "Security Instrument") dated of
even date herewith, executed by Borrower and covering the collateral more fully
described in the Security Instrument.

      6. Events of Default and Remedies. At the option of the holder of this
Note, the entire unpaid principal balance of, and all accrued interest on, this
Note shall immediately become due and payable upon the occurrence at any time of
any one or more of the following (herein referred to as an "Event of Default"):

            (a)   Borrower shall fail to pay the principal of or interest on
                  this Note as and when the same becomes due and payable in
                  accordance with the terms hereof, and such failure shall
                  continue for a period of ten (10) days after receipt of
                  written notice from Lender specifying such failure, provided,
                  however, that Lender shall be obligated to give only one (1)
                  such notice in any calendar year and, after the giving of such
                  one notice, Lender shall be entitled to exercise its remedies
                  upon any subsequent default occurring within such calendar
                  year without any requirement of notice; or

            (b)   Borrower or any other party shall fail to perform any other
                  covenant, condition, obligation or agreement set forth in this
                  Note, the Security Instrument or any other Loan Document,

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PROMISSORY NOTE - Page 2                         BORROWER _______________



                  other than as set forth in paragraph 6(a) above, and such
                  failure shall continue for a period of thirty (30) days after
                  receipt of written notice from Lender specifying such failure;
                  or

            (c)   There shall occur any default or event of default specified in
                  any Loan Document, other than as set forth in paragraphs 6(a)
                  and 6(b) above.

      If an Event of Default shall occur, Lender may (i) declare the entire
balance of this Note, principal and interest, immediately due and payable, (ii)
exercise any rights under the Security Instrument or any other right contained
in any other Loan Document, and (iii) exercise any other remedy provided by law
or equity. No remedy referred to herein is intended to be exclusive, but each
shall be cumulative, and the exercise or beginning of exercise by Lender of any
one or more of such remedies should not preclude the simultaneous or later
exercise of any or all of such remedies. Any failure of Lender to exercise any
rights or remedies available to Lender if an Event of Default should occur shall
not constitute a waiver of Lender's right to exercise such rights or remedies in
the event of any subsequent Event of Default.

      7. Past Due Interest and Late Charge. Lender may collect, to the extent
not proscribed by applicable law, a late charge for any payment of principal,
interest or any other sum due under the Loan Documents not made within ten (10)
days after its due date, such late charge to be in an amount equal to five
percent (5%) of the past due payment, provided that such late charge shall not,
when computed together with all other interest to be paid on the indebtedness
evidenced by this Note or indebtedness arising under any instrument securing the
payment hereof, exceed the Maximum Rate (as defined below). In addition, at
Lender's option, all past-due principal and, to the extent not proscribed by
applicable law, all past-due interest, shall bear interest at the Maximum Rate
or if applicable law shall not provide for a maximum nonusurious rate of
interest, at a rate per annum equal to eighteen percent (18%).

      8. Controlling Agreement. All agreements between Borrower and Lender,
whether now existing or hereafter arising and whether written or oral, are
hereby limited so that in no contingency or event whatsoever, whether by reason
of demand or acceleration of the maturity hereof or otherwise, shall the
interest contracted for, charged, received, paid or agreed to be paid to Lender
exceed interest computed at the Maximum Rate (as defined below). If, from any
circumstance whatsoever, interest would otherwise be payable to Lender in excess
of interest computed at the Maximum Rate, the interest payable to Lender shall
be reduced to interest computed at the Maximum Rate; and if from any
circumstance Lender shall ever receive anything of value deemed interest by
applicable law in excess of interest computed at the Maximum Rate, an amount
equal to any excessive interest shall be applied to the reduction of the
principal hereof and not to the payment of interest, or if such excessive
interest exceeds the unpaid balance of principal hereof, such excess shall be
refunded to the Borrower. All interest paid or agreed to be paid to Lender
shall, to the extent permitted by applicable law, be amortized, prorated,
allocated, and spread throughout the full period until payment in full of the
principal (including the period of any renewal or extension hereof) so that the
interest hereon for such full period shall not exceed interest computed at the
Maximum Rate. This section shall control all agreements between Borrower and
Lender. The term "Maximum Rate" shall mean the highest lawful rate of interest
applicable to the loan transaction evidenced by this Note taking into account
whichever of applicable federal law or Texas law permits the higher rate of
interest, and after also taking into consideration all compensation deemed
interest under applicable law.

      9. Waiver. Except as expressly otherwise provided for herein, Borrower and
all other parties now or hereafter liable or responsible for the payment of this
Note, whether as endorser, guarantor, surety or otherwise, severally waive
demand, presentment, presentment for payment, notice of intent to demand, notice
of nonpayment, notice of dishonor, diligence in collecting, grace, notice
(including notice of intent to accelerate and notice of acceleration) and
protest and consent to all renewals and extensions that from time to time may be
granted by the holder of this Note and to all partial payments herein, whether
before or after maturity. Borrower hereby further agrees that no act or omission
of Lender with reference to any property securing or intended to secure this
Note, including but not limited to failure to file or perfect any lien or
security interest, shall release the absolute obligation of Borrower and each
such endorser, guarantor or surety to pay this Note as and when due.

      10. Cumulative Rights. No delay on the part of Lender or other holder of
this Note in the exercise of any power or right under this Note, under the
Security Instrument, or under any other Loan Document, shall operate as a

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PROMISSORY NOTE - Page 3                           BORROWER _______________



waiver thereof, nor shall a single or partial exercise of any power or right
preclude other or further exercise thereof or exercise of any other power or
right. Enforcement by Lender or other holder of this Note of any security for
the payment hereof shall not constitute any election by it of remedies so as to
preclude the exercise of any other remedy available to it.

      11. Attorneys' Fees and Costs. If this Note or any installment or part
hereof is not paid when due and the same is placed in the hands of an attorney
for collection, or if this Note is collected by suit or through bankruptcy,
probate or other proceedings, Borrower agrees to pay the reasonable attorneys'
fees of the holder of this Note, together with all actual expenses of collection
and litigation and costs of court incurred by the holder of this Note.

      12. Notices. Any notice or demand required or to be given hereunder shall
be in writing, and shall be deemed to have been given and received when
deposited in a post office or official depository of the United States Postal
Service, sent by certified mail, postage prepaid, return receipt requested,
addressed as follows:

          If to Borrower:        Drew Scientific, Inc.
                                 4230 Shilling Way Dallas,
                                 Texas 75237
                                 Attn: Keith Drew

          If to Lender:          Texas Mezzanine Fund Inc.
                                 351 West Jefferson Blvd., Suite 800
                                 Dallas, Texas 75208
                                 Attn: Theresa Lee

The addresses set forth in this Note may be changed by any party by giving
notice of such change to the other party in the manner provided herein for
giving notice.

      13. Severability. In case any of the provisions of this Note shall for any
reason be held to be invalid, illegal or unenforceable, such invalidity,
illegality or unenforceability shall not affect any other provision hereof and
this Note shall be construed as if such invalid, illegal or unenforceable
provision had never been contained herein.

      14. GOVERNING LAW. THIS NOTE SHALL BE GOVERNED BY AND CONSTRUED IN
ACCORDANCE WITH THE LAWS OF THE STATE OF TEXAS AND THE LAWS OF THE UNITED STATES
APPLICABLE TO TRANSACTIONS IN TEXAS.

      15. JURISDICTION AND VENUE. ALL ACTS CONTEMPLATED BY THIS NOTE SHALL BE
PERFORMABLE IN DALLAS COUNTY, TEXAS, AND ALL SUMS PAYABLE UNDER THIS NOTE SHALL
BE PAYABLE IN DALLAS COUNTY, TEXAS. BORROWER HEREBY CONFIRMS AND AGREES THAT ALL
LEGAL ACTIONS INVOLVING THE VALIDITY OR ENFORCEMENT OF THIS NOTE SHALL HAVE
JURISDICTION AND VENUE IN DALLAS COUNTY, TEXAS.

      16. Headings. The headings of the paragraphs of this Note are inserted for
convenience only and shall not be deemed to constitute a part hereof.

      17. Successors and Assigns. This Note and all of the covenants, promises
and agreements contained herein shall be binding upon and shall inure to the
benefit of Borrower and Lender and their respective executors, administrators,
successors and assigns.

      18. Modification, Renewal and Extension. This Note is executed and
delivered by the Borrower in renewal and extension, but not in extinguishment,
of the unpaid indebtedness evidenced by, and in modification of the terms of
payment of, that certain Promissory Note dated August 3, 1999, in the stated
principal amount of $500,000.00, executed by MWI, Inc. (now known as Borrower
pursuant to those certain Articles of Amendment to the Articles of Incorporation

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PROMISSORY NOTE - Page 4                           BORROWER _______________



of MWI, Inc. filed with the Texas secretary of State's Office on November 7,
2002) and payable to the order of the Lender.

      19. FINAL AGREEMENT. THIS NOTE AND THE OTHER LOAN DOCUMENTS EXECUTED IN
CONNECTION WITH THE DISBURSEMENT OF FUNDS EVIDENCED BY THIS NOTE, REPRESENT THE
FINAL AGREEMENT BETWEEN THE PARTIES AND MAY NOT BE CONTRADICTED BY EVIDENCE OF
PRIOR, CONTEMPORANEOUS OR SUBSEQUENT ORAL AGREEMENTS OF THE PARTIES. THERE ARE
NO UNWRITTEN ORAL AGREEMENTS BETWEEN THE PARTIES.

                                           DREW SCIENTIFIC, INC.,
                                           a Texas corporation

                                           By: /s/ Keith Drew
                                               ----------------------
                                           Name: Keith Drew
                                           Title: President

PROMISSORY NOTE - Page 5